Clinical and internal medicine Books

Book SynopsisClinical psychologists and counsellors increasingly work with doctors, nurses, and medical therapists to implement psychological measures that increase the effectiveness, or mediate the ill effects, of medical treatment. This is a clear and concise guide to the body of knowledge in this field and to best practice in the clinical context.Trade Review"...offers an excellent introduction to the psychological aspects of healthcare..." (Journal of Health Psychology, Vol.16, No. 4, 2001) "...a well-written and lively book.." (British Journal of Health Psychology, September 2001) "This book could serve as a very useful basis for teaching a broad range of health professionals. Issues could then be picked up by course tutors to enable discussions of the more controversial areas and an opportunity for more in depth treatment of certain topics. Clinical and health psychologists would benefit from reading this book as an introduction to applied psychology in general medicine and surgery. Given the breadth of the book, most readers are going to find sections relevant to their own work and benefit from Peter Salmon's knowledge and experience of working in health care setting." (British Journal of Health Psychology, Sep 2001)Table of ContentsAPPLYING PSYCHOLOGY TO HEALTH CARE. Psychology Knowledge: Its Relevance and Limitations. Theories, Models and Objectives in Health Care. BECOMING ILL AND BEING ILL. Challenge, Stress and Coping. Psychobiology of Disease Processes: Heart Disease and Cancer. Psychology of Physical Symptoms. The Patient's Agenda: Beliefs and Intentions. The Psychological Impact of Physical Illness. Chronic Illness, Dying and Bereavement: Stages and Cycles of Adaptation. TREATMENT. Clinicians' Decisions and Patients' Adherence. Clinical Communication: Partnership and Opposition. Patient Empowerment: Information, Choice and Control. Hospitalization and Surgery. Psychological Treatment of Unexplained Physical Symptoms. Psychological Treatment of Physical Disease. Using Patients' Perspective to Evaluate Care. References. Index.

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Book SynopsisPapers presented at the second conference of the European Society for Philosophy of Medicine and Health Care. Topics addressed include resource allocation, medical malpractice, changes in clinical practice, the effects of social change and the place of values in health care.Table of ContentsChanging Values: Autonomy and Paternalism in Medicine andHealthcare. Commodities, Needs and Healthcare: A Communal Perspective. Changing Concepts of Medical Ethics. The Place of Values in Healthcare: Recurring Themes in thePhilosophy of Medicine. Building Networks: A Constructivist Perspective on Changes inMedicine and Healthcare. Medical Decision Analysis and the Coming Moral Crisis inHealthcare. Social Change and the Perception of Risks in MedicalPractice. Healthcare Needs, Values and Change. How Changed Values Influence Evaluative Concept. Changing Clinical Practice: A Case Study in Breast Cancer. Retrenchment and Values in a Health Organization. Hungarian Healthcare: A Challenge to Medical Values?. Medical Malpractice Phenomena: Signals for Changing Medical andHealthcare Values. Resource Allocation in Healthcare: The Role of the Courts. Changing Values and Changing Practice.

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Book SynopsisWhat is the philosophy of the NHS? What are these fundamental principles? Where do they come from and why are they so important? This book tackles each of these questions and more. Expresses the concept that the health service, armed with a substantial philosophy of health, should drive and control medicine. The central theme is that the theoretical and practical nature of health services can and must be contested.Table of ContentsA PURPOSEFUL ORGANIZATION?. The Manager's Problem. Purpose. Different Tribes?. FOUR NHS PRINCIPLES?. Need. Quality. Equality. Cost. FORTRESS NHS. Fortress NHS. Frustration. Options. Escape from the Fortress. Appendices. References and Footnotes. Index.

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Book SynopsisThis superlative text applies philosophical analysis to the daily problems of health service policy and practice. Provides readers with an understanding of the practical detail and the theoretical fundamentals of health reform.Table of ContentsPartial table of contents: The Logic of Health Reform (D. Seedhouse). INTERNATIONAL HEALTH REFORM. Health Care Reform in the United States (C. Hackler). Health Care Reform in the UK: Working for Patients? (D. Gladstone M. Goldsmith). Choosing Core Health Services in The Netherlands (H. Have). Reforming Health Care in South Africa (M. Simpson). BENEATH THE CRACKS--HEALTH REFORM AND SOCIAL JUSTICE. Going Off the Dole: A Prudential and Ethical Critique of the"Healthfare" State (S. Spicker). Health Reform and the Utopian Ideology of the New Right (M.Loughlin). Who Should Be Responsible for a Nation's Health? (V. Schubert-Lehnhardt) THE NEED FOR THEORY--A CASE STUDY IN THEPHILOSOPHY OF HEALTH PROMOTION. The Borders of Health Promotion (A. Cribb). Bad Faith and Victim-Blaming: The Limits of Health Promotion (C.Dougherty). Conclusion. Index.

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Book SynopsisAbout this book In recent years, a number of different spectroscopic techniques have been applied to the study of a wide range of biomedical topics.Table of ContentsWhole Cell Studies and Tissue Characterization by RamanSpectroscopy (G. Puppels & J. Greve). Optical Microspectroscopy and Imaging Analysis: Probing Drugs andMetal Ions in Living Cells (G. Sockalingum, et al.). Spectroscopic Studies of Drugs Used in Photodynamic Therapy (D.Phillips, et al.). Biomedical Applications of Raman Spectroscopy: Eye Lens Researchand Cardiovascular Diseases (N.-T. Yu, et al.). FTIR Spectroscopy in the Clinical Sciences (M. Jackson & H.Mantsch). EPR Spectroscopy of Biologically Relevant Free Radicals inCellular, Ex Vivo and In Vivo Systems (M. Davies & G.Timmins). Proton NMR Studies of Oxidative Stress in Disease (C. Spickett, etal.). Applications of High Resolution NMR Analysis to the Study ofInflammatory Diseases at the Molecular Level (M. Grootveld, etal.). Mass Spectroscopy in Structural Biology (R. Gallagher, etal.). Index.

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Book SynopsisThis volume provides health care professionals with a comprehensive but readable guide to the design, conduct and interpretation of health services research. It strips the research process of its technical jargon, illuminating the methods of research by an extensive use of real examples.Table of ContentsIntroduction to Health Services Research. The Foundations of Research. Developing the Research Question. Reviewing the Literature. Case Reports and Case Series. Surveys. Cohort Studies. Clinical Trials. Case-Control Studies. Other Methods of Research. Selecting the Method. Related Disciplines. Issues in Data Collection. Practical Issues in the Design and Conduct of Studies. Introduction to Data Analysis and Interpretation. Communicating the Findings. Index.

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Book SynopsisCoumarins: Biology, Applications and Mode of Action predominantly focuses on the parent compound, coumarin, and its main metabolite in humans, 7-hydroxycoumarin. It describes in detail every facet of these compounds including history, toxicology, chemistry, metabolism, analysis, clinical, veterinary and other applications, their roles as immunomodulatory agents and speculates on their mode of action.Table of ContentsPartial table of contents: History of the Development and Applications of Coumarin and Coumarin-related Compounds (I. Weinmann). The Chemistry and Occurrence of Coumarins (G. Keating & R. O'Kennedy). Coumarin as an Immunomodulator (G. Zlabinger). Mode of Action of Coumarin in the Treatment of Thermal Injuries (N. Piller). The Potential Role of Coumarins in the Therapy of Prostate Cancer (J. Mohler, et al.). Clinical and Biological Observations Associated with Coumarins (R. Thornes). Analysis of Coumarins (D. Bogan, et al.). Suggested Modes of Action of Coumarins and Some Comments on their Significance (R. O'Kennedy & R. Thornes). Index.

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Book SynopsisThis book summarises the current state of the art of our understanding of the problem of non-communicable diseases and their primary prevention. It aims to increase international awareness of the global burden of non-communicable diseases and in particular to highlight the trends in developing countries; evaluates the impact of changes in diet, nutrition and lifestyle that predispose to chronic non-communicable diseases in modern societies; shares knowledge of the growing problems on non-communicable diseases and experiences related to its prevention between health professionals of developing and developed countries; identifies and prioritises major research issues and suggest strategies to deal with the global epidemic of chronic non-communicable diseases.Trade Review"This book represents a well organized and edited report of the Sixth Annual Public Health Forum.... Surely, [the Forum] and this book...borrowing a sentence from the preface, have 'given a significant contribution to the...acceleration of action that is required to counter and reverse...diet-related NCD.'" (European Journal of Public Health, Vol. 9, No. 1, 1999)Table of ContentsOverview of Diet-Related Non-Communicable Diseases. Prenatal Influences on Disease in Later Life. Cardiovascular Disease and Diabetes in Migrants - Interactions Between Nutritional Changes and Genetic Background. Inequalities in Diet and Health Dietary Fats and Non-Communicable Diseases. Diet and Large Bowel Cancer. Interactions Between Diet and endogenous Hormones: Possible Role in Breast Cancer Assessing the Net Effect of Alcohol Consumption on Mortality. The Public Health Impact of Globalisation of Food Trade Some Aspects of Norwegian Nutrition and Food Policy Symposium: The Burgeoning Global Burden of Obesity. Workshop Reports Diet, Lifestyle and Chronic Disease: Lessons From Contrasting Worlds. Where Do We Go From Here in Public Health? Index.

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Book SynopsisCommunicable Disease Epidemiology and Control Edited by Norman Noah King''s College School of Medicine and Dentistry, London, UK, and Mary O''Mahony Public Health Laboratory Service, London, UK With the growing interest in communicable diseases and their control worldwide, largely due to new and re-emerging infections, there is a need for up-to-date information in this continually changing field. Timely and wide ranging, Communicable Disease: Epidemiology and Control addresses many of the contemporary issues and provides: * Detailed and concise examination of management issues, such as commissioning and contracting, setting up an incident room, and legal aspects * A practical approach * An examination of a wide spectrum of issues in communicable diseases, including cholera, tuberculosis, Helicobacter pylori, and sexually transmitted diseases This volume is an invaluable resource for microbiologists, epidemiologists and all professionals involved in public health.Table of ContentsEPIDEMIOLOGY. Global Trends in Communicable Disease Control (A. Cliff & P. Haggett). Recent Trends in the Epidemiology and Management of Sexually Transmitted Infections (I. Simms & A. Nicoll). The Global Resurgence of Cholera (E. Mintz, et al.). The Resurgence of Tuberculosis (J. Grange). The Epidemiology of Hantavirus Pulmonary Syndrome (R. Khabbaz & J. Childs). Consequences of Helicobacter pylori Infection (R. Feldman & D. Strachan). MANAGEMENT ISSUES. Commissioning and Contracting Issues in Communicable Disease Control (G. Duckworth & A. Cummins). Setting Up an Incident Room (E. Mitchell). Legal Aspects of Communicable Disease Control (M. Painter & J. Button). Surveillance of Infectious Disease in a Region (S. Palmer). Appendix. Index.

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Book SynopsisConducting GCP-Compliant Clinical Research Wendy Bohaychuk and Graham Ball Good Clinical Research Practices, UK and Canada The overall aim of this work is to provide a reference book which describes the general framework for conducting GCP-compliant clinical research, particularly pharmaceutical industry clinical research. Wendy Bohaychuk and Graham Ball run a consultancy, GCRP Ltd., which has conducted over 820 GCP audits involving more than 200 companies in the last 10 years. More than 5,000 individuals have been involved in their training courses to help people perform GCP-compliant clinical research. They have authored several books and articles including: Standard operating procedures for investigators Standard operating procedures for sponsors and CROs GCP - an indexed reference Drawing on their wealth of experience, they have produced this enlightening and practical reference work which fills an educational gap in the understanding of GCP atTable of ContentsThe Current Roles for Conducting Clinical Research - Setting up Clinical Studies - Ethical Considerations - Monitoring and Safety Reporting - Collecting Data with Integrity - Managing Study Medications/Devices - Final Stages in Clinical Studies.

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Book SynopsisVolume I is divided into two parts. Part B of volume I in theBen cao gang museries offers a translation of portions of chapter 3 and the complete chapter 4, devoted to pharmaceutical drugs for diseases. This volume is a continuation of volume I, part A. The first portion of chapter 3 is found in part A. TheBen cao gang muis a sixteenth-century Chinese encyclopedia of medical matter and natural history by Li Shizhen (15181593). The culmination of a sixteen-hundred-year history of Chinese medical and pharmaceutical literature, it is considered the most important and comprehensive book ever written in the history of Chinese medicine and remains an invaluable resource for researchers and practitioners. This nine-volume series reveals an almost two-millennia-long panorama of wide-ranging observations and sophisticated interpretations, ingenious manipulations, and practical applications of natural substances for the benefit of human health. Paul U. Unschuld's annotated translation of theBen cao gang mu, presented here with the original Chinese text, opens a rare window into viewing the people and culture of China's past.

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Book SynopsisThe first edition of this successful reader brought together key readings in the area of developmental cognitive neuroscience for students. Now updated in order to keep up with this fast moving field, the volume includes new readings illustrating recent developments along with updated versions of previous contributions.Trade Review"For child language researchers who wish to gain some background knowledge in this field, we reccommend this volume highly. This text is suitable for academics and students alike. It is an excellent source, and the associated teaching resources available on-line are well constructed and highly useful... The clarity and coherence of the overall argumements contained in the volume make the book a worthwhile component of any developmentalist's library." Vincent Reid & Tricia Striano, Cultural Ontogeny Group, Max Planck Institute for Evolutionary AnthropologyTable of ContentsContributors. Preface.. Part I: Perspectives on Development. Introduction. 1. Critique of the Modern Ethologists Attitude (Konard Lorenz). 2. The Problem of Change (Susan Oyama). 3. The Epigenetic System and the Development of Cognitive Functions (Jean Piaget). 4. From Gene to Organism: The Developing Individual as an Emergent, Interactional, Hierachical System (G. Gottlieb). Part II: Brain Maturation. Introduction. 5. General Principles of CNS Development (R .S. Nowakowski and N.L. Hayes). 6. Intrinsic and Extrinsic Determinants of Neocortial Parcellation: A Radical Unit Model (P. Rakic). 7. Positron Emission Tomography Study of Human Brain Functional Development (Harry T. Chugani, Michael E. Phelps and John C. Mazziotta). 8. Morphometric Study of Human Cerebral Cortex Developemt (Peter R. Huttenlocher). Part III: Brain Maturation and Cognition. Introduction. 9. The Development of Visual Attention: A Cognitive Neuroscience Perspective (Mark H. Johnson). 10. The Ontogeny of Human Memory: A Cognitive Neuroscience Perspective (C.A. Nelson). Part IV: Brain Plasticity. Introduction. 11. Experience and Brain Development (William T. Greenough, James E. Black and Christopher S. Wallace). 12. Do Cortical Areas Emerge from a Protocortex? (Dennis D. M. O'Leary). 13. Emergence of Order in Visual System Development (C.J. Shatz). Part V: Brain Plasticity and Cognition. Introduction. 14. Specificity and plasticity in Neurocognitive Development in Humans (H. Neville and D. Bavelier). 15. Linguistic, Cognitive, and Affective Development in Children with Pre- and Perinatal Focal Brain Injury: A Ten-Year Overview from the San Diego Longitudinal Project (Joan Stiles, Elizabeth A. Bates, Donna Thal, Doris A. Trauner, and Judy Reilly). 16. Cortical Plasticity Underlying Perceptual, Motor, and Cognitive Skill Development: Implications for Neurorehabilitation (Michael M. Merzenich, Beverly A. Wright, William Jenkins, Christina Xerri, Nancy Byl, Steve. Miller and Paula. Tallal). 17. The Instinct to Learn (Peter Marler). Part VI: Self Organization and Development. Introduction. 18. Self-Organization in Developmental Processes: Can system Approaches Work? (Esther Thelen). 19. Development Itself is the Key to Understanding Developmental Disorders. Annette Karmiloff-Smith). 20. Object Recognition and Sensitive Periods: A Computational Analysis of Visual Imprinting (Randall C. O’Reilly and Mark H. Johnson). Part VII: New Directions. Introduction. 21. Connectionism and the Study of Change: Elizabeth Bates and Jeffrey L. Elman). 22. A Model System for Studying the Role of Dopamine in Prefrontal Cortex During Early Development in Humans (Adele Diamond). 23. Genes and Brain: Individual Differences and Human Universals: Bruce F. Pennington). Name Index. Subject Index.

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Book Synopsisaeo an established bestseller which, in the new edition, is the only current text to give a modern coverage of the subject at this level aeo contains a large number of new illustrations and diagrams aeo covers the significant advances made in our current understanding of the eukaryotic genome.Table of ContentsChemical cytology of the microbial cell; Population growth and death; Substrate uptake and entry to the cell; Energy production; Monomer synthesis; Polymer synthesis and metabolism; Regulation; Growth of individual cells; Morphogenesis and differentiation; Further reading; Glossary; Index

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Book SynopsisThe first edition of An Aid to the MRCP Short Cases rapidly estabished itself as a classic and has sold over 25,000 copies. The aims of this revised and extended second edition are the same as those of the first: to provide a comprehensive guide for those preparing for the short cases section of the Membership of the Royal College of Physicians examination. The MRCP examination is a major hurdle for all trainee hospital physicians and has a failure rate of over 70%. The largest part of the book consists of 200 short cases that are presented in order of frequency of their occurrence in the examination (based on an extensive survey of successful candidates). The clinical features of each case are fully covered and supported by illustrations and photographs. The emphasis throughout the book is on examination technique and how to present the clinical information in the style that the examiners expect. In short, it is an indispensable guide for anyone pTrade Review"...this is an excellent book, giving good advice on how to become a skilled, thoughtful and knowledgeable physician and hence how to become a MRCP (UK)" Journal of the Royal College of Physicians of London, on the previous edition "The case-by-case approach is useful in preparing for Medicine finals. Together with the examination routines, the book becomes a kind of alternative textbook to conventional clinical examination books such as McCleods." 2nd Opinion, The Magazine of the Scottish Medical Schools "...an invaluable companion to undergraduates in medical finals. It is easy to filter out the more obscure cases but this being said, the vast majority of the information is relevant to House Officers-to-be. This book is excellent value for money; the buy is well worth it." Leech Y Gelen, University of Wales College of Medicine GazetteTable of ContentsPreface to the second edition ix Preface to the first edition xi Introduction xiii Section 1: Preparation 1 Section 2: Examination Routines 7 1 Heart 10 2 Abdomen 14 3 Fundi 18 4 Hands 20 5 Legs 24 6 Chest 28 7 Spot diagnosis 31 8 Eyes 35 9 Face 37 10 Arms 38 11 Neck 42 12 Ask questions 43 13 Pulse 46 14 Visual fields 48 15 Skin 49 16 Gait 51 17 Rash 53 18 Legs and arms 54 19 Cranial nerves 55 20 Thyroid status 58 Section 3: 200 Short Case Records 61 1 Diabetic retinopathy 65 2 Hepatosplenomegaly 69 3 Mitral stenosis (lone) 71 4 Rheumatoid hands 73 5 Mixed mitral valve disease 76 6 Dullness at the lung base 78 7 Splenomegaly (without hepatomegaly) 80 8 Optic atrophy 82 9 Chronic liver disease 84 10 Polycystic kidneys 86 11 Paget’s disease 87 12 Psoriatic arthropathy/psoriasis 90 13 Other combinations of mitral and aortic valve disease 93 14 Mixed aortic valve disease 94 15 Systemic sclerosis/CRST syndrome 96 16 Exophthalmos 98 17 Hepatomegaly (without splenomegaly) 101 18 Spastic paraparesis 102 19 Fibrosing alveolitis 103 20 Aortic incompetence (lone) 104 21 Hemiplegia 106 22 Old tuberculosis 108 23 Acromegaly 109 24 Aortic stenosis (lone) 112 25 Graves’ disease 114 26 Ocular palsy 117 27 Mitral incompetence (lone) 121 28 Motor neurone disease 123 29 Goitre 126 30 Ulnar nerve palsy 129 31 Visual field defect 131 32 Peripheral neuropathy 134 33 Hypertensive retinopathy 136 34 Resuscitation Annie 138 35 Cerebellar syndrome 142 36 Retinitis pigmentosa 144 37 Carcinoma of the bronchus 145 38 Parkinson’s disease 148 39 Chronic bronchitis and emphysema 150 40 Hypothyroidism 152 41 Osler–Weber–Rendu syndrome 155 42 Abdominal mass 157 43 Dystrophia myotonica 159 44 Bronchiectasis 161 45 Wasting of the small muscles of the hand 162 46 Generalized lymphadenopathy 165 47 Papilloedema 166 48 Diabetic foot 168 49 Nystagmus 171 50 Old choroiditis 174 51 Neurofibromatosis (von Recklinghausen’s disease) 176 52 Erythema nodosum 178 53 Horner’s syndrome 180 54 Old polio 182 55 Ankylosing spondylitis 184 56 Abnormal gait 186 57 Irregular pulse 189 58 Single palpable kidney 190 59 Ascites 191 60 Sturge–Weber syndrome 193 61 Necrobiosis lipoidica diabeticorum 195 62 Ventricular septal defect 197 63 Lower motor neurone VIIth nerve palsy 198 64 Clubbing 201 65 Retinal vein thrombosis 203 66 Eisenmenger’s syndrome 205 67 Crohn’s disease 207 68 Mitral valve prolapse 209 69 Cervical myelopathy 211 70 Patent ductus arteriosus 213 71 Tricuspid incompetence 214 72 Purpura 215 73 Xanthomata 218 74 Drug-induced extrapyramidal syndrome 220 75 Bilateral parotid enlargement/Mikulicz’s syndrome 221 76 Primary biliary cirrhosis 222 77 Lupus pernio 224 78 Muscular dystrophy 226 79 Prosthetic valves 228 80 Addison’s disease 229 81 Cushing’s syndrome 231 82 Friedreich’s ataxia 234 83 Peutz–Jeghers syndrome 236 84 Systemic lupus erythematosus 237 85 Superior vena cava obstruction 239 86 Vasculitis 241 87 Deep venous thrombosis/Baker’s cyst/cellulitis 244 88 Cor pulmonale 247 89 Myelinated nerve fibres 248 90 Charcot–Marie–Tooth disease 249 91 Cataracts 251 92 Idiopathic haemochromatosis 253 93 Chest infection/consolidation/pneumonia 255 94 Coarctation of the aorta 256 95 Bulbar palsy 257 96 Choreoathetosis 258 97 Dysarthria 260 98 Dysphasia 261 99 Ehlers–Danlos syndrome 263 100 Erythema ab igne 265 101 Marfan’s syndrome 267 102 Myasthenia gravis 269 103 Osteoarthrosis 272 104 Raised jugular venous pressure 274 105 Pretibial myxoedema 275 106 Retinal artery occlusion 277 107 Vitiligo 279 108 Tophaceous gout 282 109 Fallot’s tetralogy with a Blalock shunt 284 110 Slow pulse 285 111 Guillain–Barré syndrome (acute inflammatory demyelinating polyradiculopathy) 286 112 Pneumonectomy/lobectomy 288 113 Obesity/pickwickian syndrome 290 114 Dermatomyositis 293 115 Hypopituitarism 295 116 Swollen knee 297 117 Pseudobulbar palsy 299 118 Pemphigus/pemphigoid 300 119 Syringomyelia 303 120 Tuberculosis/apical consolidation 305 121 Rheumatoid lung 307 122 Tuberous sclerosis/adenoma sebaceum 308 123 Proximal myopathy 310 124 Pseudoxanthoma elasticum 311 125 Radiation burn on the chest 313 126 Subacute combined degeneration of the cord 314 127 Holmes–Adie–Moore syndrome 315 128 Peripheral vascular disease 316 129 Transplanted kidney 318 130 Glaucoma/peripheral field loss 320 131 Nephrotic syndrome 322 132 Jugular foramen syndrome 323 133 Herpes zoster 325 134 Henoch–Schönlein purpura 327 135 Polymyositis 329 136 Argyll Robertson pupils 330 137 Congenital syphilis 331 138 Carpal tunnel syndrome 333 139 Cerebellopontine angle lesion 335 140 Dextrocardia 336 141 Down’s syndrome 337 142 Gynaecomastia 338 143 Absent ankle jerks and extensor plantars 340 144 Lichen planus 341 145 Lateral popliteal (common peroneal) nerve palsy 343 146 Ptosis 345 147 Osteogenesis imperfecta 348 148 Pulmonary stenosis 349 149 Raynaud’s phenomenon 350 150 Turner’s syndrome 352 151 Mycosis fungoides 354 152 Morphoea 356 153 Laurence–Moon–Bardet–Biedl syndrome 358 154 Short stature 360 155 Pseudohypoparathyroidism 362 156 AIDS related 365 157 Porphyria 368 158 Lupus vulgaris 370 159 Cannon waves 372 160 Polycythaemia rubra vera 373 161 Asteroid hyalosis 374 162 Pernicious anaemia 375 163 Dermatitis herpetiformis 377 164 Urticaria pigmentosa (mastocytosis) 379 165 Pneumothorax 380 166 Tabes 381 167 Tylosis 383 168 Klippel–Feil syndrome 385 169 Pendred’s syndrome 387 170 Secondary syphilis 389 171 Ectodermal dysplasia 391 172 Old rickets 393 173 Partial lipodystrophy 395 174 Fabry’s disease 397 175 Subclavian-steal syndrome 399 176 Reiter’s syndrome/keratoderma blenorrhagica 401 177 Carcinoid syndrome 403 178 Infantile hemiplegia 404 179 Pulmonary incompetence 406 180 Hereditary spherocytosis 408 181 Juvenile chronic arthritis 409 182 Cystic fibrosis 411 183 Infective endocarditis 413 184 Malignant melanoma 415 185 Leg oedema 417 186 Acanthosis nigricans 419 187 Drusen 422 188 Yellow nail syndrome 423 189 Klinefelter’s syndrome/hypogonadism 424 190 Keratoacanthoma 428 191 Thalamic syndrome 429 192 Atrial septal defect 430 193 Pyoderma gangrenosum 431 194 Multiple sclerosis 433 195 Felty’s syndrome 435 196 Hypertrophic obstructive cardiomyopathy 436 197 Radial nerve palsy 437 198 Lateral medullary syndrome (Wallenberg’s syndrome) 438 199 Psychogenic/factitious 440 200 Normal 444 Section 4: Experiences Anecdotes Tips Facts and Figures Quotations 445 Experiences 447 The power and range of the candidate’s observations 449 The candidate’s examination technique 451 The clinical competence of the candidate 453 Common errors 454 Look first 455 Double pathology 456 Tell them of the expert that told you 456 Apologies accepted 457 ‘Even though I didn’t mean to say it—I did’ 457 Invigilator’s diaries 458 Fly on the wall—complete accounts 460 Ungentlemanly clinical methods 466 Some experiences written in the first person 466 Miscellaneous ‘pass’ experiences 467 You never know you’ve failed until the list is published 479 Survivors of the storm 483 Some ‘fail’ experiences 486 Downward spirals 491 Anecdotes 493 Some anecdotes in the first person 498 Useful tips 501 Facts and figures 502 Quotations 503 Adopt good bedside manners 503 Practise clinical examination and presentation 504 Get it right 505 Listen obey and do not stray 505 One wrong does not make one fail 506 If you say less they want more 506 If you know it—say it 506 Humility is more persuasive than self-righteousness 507 Keep cool: agitation generates aggression 507 Simple explanations raise simple questions 507 Think straight look smart and speak convincingly 508 You have seen it all before 508 Use your eyes first and most 508 Doing and forgetting 509 Examiners are different 509 Appendices 511 1 Checklists 513 2 Examination frequency of MRCP short cases 517 3 Examination frequency of examiners’ instructions 522 4 Pocket Snellen’s chart 524 5 Texidor’s twinge and related matters 525 6 Colour photographs of some MRCP short cases 527 7 Detailed contents of Section 4 544 Index 547

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Book SynopsisUsing images and anatomic illustrations, Rad Tech''s Guide to MRI: Imaging Procedures, Patient Care, and Safety provides the reader with a quick overview of MRI for quick reference and examination preparation. As part of the Rad Tech''s Guide Series, this volume features an overview of anatomy, imaging tips, scanning procedures, and the latest information on protocols--all in the context of patient care and safety. Each book in the Rad Tech''s Guide Series covers the essential basics for those preparing for their certifying examinations and those already in practice.Table of Contents1 Patient Care and Safety for Magnetic Resonance Imaging 1 Introduction to Patient Care and Safety for MRI 3 Screening Patients and Personnel 3 Ancillary Equipment and Implants 8 Assessing and Monitoring 19 Contrast Agents for MRI 21 Life-Threatening Situations 24 Safety Precautions for Placement of Electrical Conductors 24 Environmental Considerations Temperature and Humidity 25 Gauss Line and Magnetic Field Strength 25 Emergency Procedures 27 Quench 27 Evacuation 29 Biologic Considerations 29 Radio Frequency Fields 29 Static Field Strength 32 FDA Guidelines for State Magnetic Fields 35 Gradient Magnetic Fields (Time-Varying Magnetic Fields) 35 Future Safety Considerations 38 2 Introduction to Clinical MRI Procedures 41 Introduction to Clinical MR. 41 Patient Preparation for Clinical: MRI 42 Special Considerations for Pediatric Patients 43 Choosing the Right Protocol 43 Parameters for Image Contrast in MRI 44 Pulse Sequences 47 Parameters for Signal-to-Noise and Resolution 51 Creating Artifact-Free Images 53 Types of FDA-Approved Contrast Agents 55 3 Imaging Procedures: Head and Neck Imaging. 57 Introduction of Head and Neck MRI 57 Standard Protocols for Imaging of the Brain 58 Anatomy and Physiology of the Brain 60 Patient Set-Up and Positioning for Brain Imaging 64 Indicators for Contrast Agents for Brain Imaging 65 Indicators for High-Resolution Brain Imaging 67 4 Spine Imaging Procedures 71 Introduction to Spine Magnetic Resonance Imaging 71 Standard Protocols for Imaging the Spine 72 Additional Spine Sequences for High Resolution 74 Anatomy and Physiology of the Spine 74 Patient Set-Up and Positioning for Spine Imaging 76 Indicators for Contrast Agents for Spine Imaging 79 Cervical Spine Imaging 80 Thoracic Spine Imaging 80 Lumber Spine Imaging 82 5 Musculoskeletal Imaging Procedures 85 Introduction to Musculoskeletal Magnetic Resonance Imaging 86 Standard Protocols for Imaging the Musculoskeletal System 86 Patient Set-Up and Positioning for Musculoskeletal Imaging 90 Indicators for Contrast for Musculoskeletal Imaging 92 Standard Dose and Administration for Gadolinium 92 Magnetic Resonance Imaging of the Temporomandibular joint 93 Magnetic Resonance Imaging of the Upper Extremities 94 Magnetic Resonance Imaging of the Lower Extremities 101 6 Thorax Imaging Procedures. 111 Introduction to Thorax Magnetic Resonance Imaging 111 Standard Protocols for Imaging the Thorax 112 Patient Set-Up and Positioning for Thorax Imaging 116 Indicators for Contrast Agents for Thorax Imaging 121 Magnetic Resonance Imaging of the Breast 123 7 Abdomen Imaging Procedures 131 Introduction to Abdomen Magnetic Resonance Imaging 131 Standard Protocols for Imaging the Abdomen 132 Anatomy and Physiology of the Abdomen 136 Patient Set-Up and Positioning for Abdomen Imaging 138 Indicators for Contrast Agents for Abdomen Imaging 140 8 Pelvis Imaging Procedures 143 Introduction to Pelvis Magnetic Resonance Imaging 143 Standard Protocols for Imaging the Pelvis 144 Patient Set-Up and Positioning for Pelvis Imaging 144 Indicators for Contrast Agents for Pelvis Imaging 146 Standard Dose and Administration for Gadolinium 147 Standard Protocols for Female Pelvis MRI 147 Standard Protocols for Male Pelvis MRI 152 9 Vascular Imaging Procedures 155 Introduction to Vascular Magnetic Resonance Imaging 156 Flow Imaging: An Overview 156 Magnetic Resonance Angiography: An Overview 158 Body Magnetic Resonance Angiography Changes 163 Anatomy and Physiology of the Vascular System 166

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Book SynopsisPharmacovigilance from A to Z is an authoritative text focusing on the common questions and procedures involved in prescribed-drug monitoring. The alphabetized format provides an easy-to-use reference, while a separate section of the book guides the reader logically from topic to topic to form related chapters.Table of ContentsForeword. Introduction. Abbreviations. A. B. C. D. E. F. G. H. I. JKL. M. N. O. PQ. R. S. T. U. V. W. XYZ.

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Book SynopsisHelps veterinary nurses with various types of calculations. This book includes numerous worked examples to develop the reader's confidence in carrying out the procedures involved. It enables the reader to progress from an explanation of the arithmetic principles involved, to the application of these principles to useful veterinary calculations.Trade Review"every veterinary practice should keep a copy in its library, so that the practice nurses can remind themselves of how to work out calculations in their day-to-day work. This is a very readable book and one that I unreservedly recommend.” Veterinary Nursing Table of ContentsPreface. Disclaimer. Common Abbreviations Used in Text. Units, Conversion Factors and Related Medical Abbreviations. Basic Principles. Changing the Concentration of a Solution. Calculating Energy Requirements. Dosages - Oral Route. Dosages - Injections. Rehydration of the Patient. Fluid Therapy - Rates of Administration. Anaesthetic Gases - Flow Rates. Radiography. Value Added Tax (VAT). Examination Techniques. Index

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Book SynopsisThis revision of a popular title gives an overview of internal medicine, highly relevant as a study and clinical aid. Complex material is distilled and organized in a logical, succinct and accessible way, with integration of clinical, laboratory/imaging and therapeutic information. Extensively re-written with the assistance of two new authors, each chapter has been carefully reviewed. Up-to-date and portable, this little book caters to day-to-day clinical decision making, while also targeting postgraduate examination preparation. Each body system is dealt with in a separate chapter, with additional chapters on pharmacology and best evidence. In addition, material is further organized into clinical clues, pathophysiology, diagnosis, and treatment. For medical students and junior doctors this is an important study aid and clinical reference. For allied health practitioners it is a straightforward reference, which can be used in the office or on the wards. For established practTrade Review"Money extremely well spent, I would recommend it to anyone trying to pass finals at the moment." (Sphincter, Liverpool Medical Students' Society Magazine) "This is an excellent pocket-sized edition, which will prove to be invaluable in revision for the membership examinations.... A useful reference book, both for learning and revision. It achieves what many MCQ books fail to deliver - the complete answer, not just the reason why a stem is correct..." (Barts and the London Chronicle, Autumn 2000) "...It is tight-lipped. It neatly summarises each field/subject. It uses tables and bulleted sentences. It fits neatly into a pocket. It tells you nothing that isn't essential. It's about internal medicine. It does exactly what is says on the cover." (Black Bag - Bristol Medical School Gazette, 2000)Table of ContentsPreface. Acknowledgements. Abbreviations. 1 Epidemiology, sSatistics and Evaluation of the Literature. 2 Pharmacology. 3 Cardiology. 4 Respiratory Medicine. 5 Gastroenterology. 6 Hepatology. 7 Nephrology. 8 Neurology. 9 Endocrinology. 10 Haematology. 11 Oncology and palliative medicine. 12 Immunology and allergy. 13 Rheumatology. 14 Infectious diseases. 15 Medical dermatology. 16 Psychiatry. Index.

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Book SynopsisBotulinum toxin A is a remarkably versatile treatment with a steadily expanding list of indications, which include strabismus, hemifacial spasm, focal dystonias such as spasmodic torticollis, dysphonia and writer's cramp, as well as adult and childhood spasticity.Trade Review"...a comprehensive and succinct overview..." Hospital Update "...an essential companion..." JNNP "...a valuable tool...recommended..." Neuro-ophthalmologyTable of ContentsPART ONE: General. Chp 1. History and current applications of botulinum toxin *Moore & Naumann. Chp 2. The molecular basis of the activity of botulinum toxin. *Montecucco & Rosetto. Chp 3. General and clinical aspects of treatment with botulinum toxin. *Moore & Naumann. Chp 4. EMG and Imaging. *Poewe and Wissel. PART TWO: Disorders of Movement. Chp 5. Dystonia. *Brin. 5.1 Cranio-facial dystonia. *Brin. 5.2 Laryngeal and pharyngeal dystonia. *Blitzer, Sulica & Verhayden. 5.3 Cervial and axial (spinal) dystonia. *Benecke. 5.4 Limb and occupational dystonia (including non limb variants). *Sheean. Chp 6. Spasticity in adults: Introduction. *Gracies & Simpson. 6.1 Upper limbs and neck. *Gracies & Simpson. 6.2 Lower limbs. *Hefter. Chp. 7 Spasticity in children. *Graham, Heinen & Berweck. Chp 8. Other involuntary muscle activity - Tremor. *Findlay & Senanayake. Chp 9. Exotic movement disorder indications. *Jankowic & M Thomas. PART THREE: Autonomic Disorders. Chp 10. Disorders of secretion. *Naumann. Chp 11. Pelvic floor and gastrointestinal uses. *Jost. PART FOUR: Other Indications. Chp 12. Ophthalmic. *Lee. Chp 13. Pain. *Nurmikko. Chp 14. Cosmetic Use. *Lowe & Sommer. Chp 15. The future of neurotoxins. *Moore & Naumann

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Book SynopsisEdited by an orthopaedic surgeon and a haematologist who are leading specialists in the treatment of haemophilia, Inhibitors in Patients with Haemophilia reviews the different haemostatic products and protocols for the control of bleeding and surgery in haemophilic patients with inhibitors. The book draws together in a single volume all of the clinical issues involved in the treatment of inhibitors from numerous specialists worldwide. It will be an invaluable resource for all those treating inhibitors in people with haemophilia.Table of ContentsContributors. Preface. HAEMATOLOGY. 1 Natural history of inhibitor in severe haemophilia A and B: incidence and prevalence. Jeanne Lusher (USA). 2 Characterisation of inhibitors in congenital haemophilia. Kathelijne Peerlinck and Marc Jacquemin (Belgium). 3 Incidence and prevalence of inhibitors and type of blood product in haemophilia A. Christine Lee and Thynn Thynn Yee (UK). 4 Genetic basis of inhibitor development in severe haemophilia A and B. Edward Tuddenham (UK) and Johannes Oldenburg (Germany). . MANAGEMENT OF TREATMENT. 5 Therapeutic products: human FVIII, porcine FVIII, prothrombin complex concentrates, activated prothrombin complex concentrates and recombinant FVIIa. Thierry Lambert (France). 6 Methods: plasmapheresis and protein A immuno-adsorption. Eric Berntorp (Sweden). 7 Venous access in children with inhibitors. Rolf Ljund (Sweden). IMMUNETOLERANCE. 8 Immunetolerance: high dose regimen. Hans Brackmann and Thomas Wallny (Germany) (To be agreed). 9 Immunetolerance: low dose regimen. Eveline Mauser-Bunschotten (Netherlands). 10 Immunotolerance and choice of concentrates. Wolfgang Kreutz (Germany). 11 Immunetolerance regimen: the North America registry (To be agreed). Donna DiMichele (USA). . MEDICAL MANAGEMENT OF BLEEDING EPISODES. 12 Treatment of bleeding episodes in children. Joan Tusell (Spain). 13 General medical management of bleeding episodes: haemarthroses, muscle haematoma, mucocutaneous bleed, haematuria. Manuel Quintana (Spain). 14 Life- and limb-threatening bleeding episodes and intracranial bleeds. Sam Schulman (Sweden). . INHIBITORS IN HAEMOPHILIA B. 15 Inhibitors in haemophilia B patients. India Warrier (USA). 16 Inhibitors in mild/moderate haemophilia. Charles Hay (UK). 17 Acquired inhibitors to FVIII. Craig Kessler (USA). . MUSCULOSKELETAL ISSUES. 18 Pathogenesis of musculoskeletal complications of haemophilia. E C Rodriguez-Merchan (Spain). 19 Orthopaedic management of haemarthroses. E C Rodriguez-Merchan (Spain). 20 Synoviorthesis with Rifampicin. Horacio Caviglia (Argentina) and F Fernandez-Palazzi (Venezuela). 21 Radiosynoviorthesis. Eric Berntorp (Sweden). 22 Musculoskeletal MRI. Rachel Nuss and Jerome Wiedel (USA). 23 Iliopsoas haematomas and limb compartment syndromes. Michael Heim (Israel). 24 Pseudotumours. Marvin Gilbert (USA). 25 Haemophilia patients with inhibitors: a rheumatologist´s point of view. John York (Australia). 26 Rehabilitation. Felipe Querol and José Aznar (Spain). 27 Physiotherapy. Karen Beeton (UK). 28 Elective orthopaedic surgery in patients with high responding inhibitors-. Ivan Hvid, J Soballe and J Ingerslev (Denmark). . GENERAL SURGERY. 29 General and emergency surgery in patients with high responding inhibitors. Owen Smith & Barry White (Ireland). 30 Dental extractions. Uri Martinowitz (Israel). . PSYCHOSOCIAL ISSUES. 31 Psychological issues. Pilar Arranz (Spain). . 32 GENERAL STRATEGY FOR MANAGEMENT OF INHIBITOR PATIENTS. Inga Scharrer (Germany). Index

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Book SynopsisMedicine and Surgery is an exciting new book that contains the core information needed by medical students in the run up to exams. This is the only book available that covers both medicine and surgery. It encompasses all of the major systems and core subjects Every condition is discussed under the key headings of definition, epidemiology, aetiology, pathophysiology, clinical features, investigations, management and prognosis The content follows a very consistent and familiar style, so that information is easily accessible, digestible and memorable Each chapter opens with an overview of clinical method before discussing the most common conditions relevant to that speciality Medicine and Surgery: A Concise Textbook is written specifically for medical students as essential revision preparation, for junior doctors as a refresher on the wards and for other allied health professionals who want a quick remindTrade Review''I like the way the book goes through each disease using the same system of definition, aetiology etc. This makes it easier to learn….The content is exactly what the undergraduate brain needs” Final year student, University of OxfordTable of Contents1 Principles and Practice of Medicine and Surgery. 2 Cardiovascular System. 3 Respiratory System. 4 Gastrointestinal System. 5 Hepatic, Biliary & Pancreatic Systems. 6 Genitourinary Systems. 7 Nervous System. 8 Musculoskeletal System. 9Dermatology & Soft Tissues. 10 Breast Disorders. 11Endocrine System. 12 Haematological System. 13 Nutritional and Metabolic Disorders. 14 Genetic Syndromes. 15 Overdose, Poisoning and Addictions. Index

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Book SynopsisWith contributions from over 100 leading authorities within the fields of exercise physiology, clinical internal medicine, sports medicine and traumatology, this book offers comprehensive coverage of both basic science and clinical aspects of sports injury and physical activity.Trade Review"This book is a welcome addition to the field of sports medicine and nicely covers a wide range of topics. It provides up-to-date, practical, and theoretical information for those who study or take care of active populations. Busy clinicians will find this to be a helpful reference that they routinely consult."(Scott Paluska, MD, @Doody's Review Service)Table of ContentsSection 1: Basic science of physical activity and sports injuries - Principles of training. 1.1 Cardiovascular and respiratory adaptation to physical training. 1.2 Metabolism during exercise - energy expenditure, hormonal changes. 1.3 Skeletal muscle: physiology, training and repair after injury. 1.4 Neuromuscular aspects and joint neurophysiology in exercise - adaptive responses evoked by strength training. 1.5 Biomechanics of locomotion. 1.6 Connective tissue in ligaments, tendon and muscle: physiology and repair, and musculoskeletal flexibility 1.7 Cartilage tissue - loading and overloading. 1.8 Bone tissue -training and injury. Section 2: Aspects of human performance. 2.1 Recovery after training - inflammation, metabolism, and tissue repair, overtraining. 2.2 Principles of Rehabilitation following sports injuries. 2.3 Physical activity and environment. 2.4 Nutrition and fluid intake with training. 2.5 Ergogenic aids (doping) and pharmacological injury treatment. Section 3: Physical achievements vs sports injury. 3.1 Epidemiology and prevention of sports injuries. 3.2 Exercise as disease prevention. 3.3 Physical activity in the elderly. 3.4 Exercise in healthy children and in those who have a chronic disease. 3.5 Disabled individuals and exercise. Section 4: Exercise in acute and chronic medical diseases. 4.1 Athletes' heart - cardiovascular and peripheral vessel diseases. 4.2 Exercise and infectious diseases. 4.3 Osteoarthritis. 4.4 Exercise in the treatment of type 2 and 1 diabetes. 4.5 Asthma and chronic airway disease. 4.6 Amenorrhea, osteoporosis, and eating disorders in athletes. 4.7 Physical Activity and obesity. 4.8 Exercise in acute snd chronic medical conditions: gastrointestinal considerations. Section 5: Imaging in Sports Injuries. 5.1 Imaging in Sports Injuries. Section 6: Regional considerations. 6.1 Lower leg, ankle and foot. 6.2 Knee. 6.3 Athletic injuries to the hip, groin and pelvis. 6.4 Head injuries. 6.5 Spine. 6.6 Shoulder. 6.7 Elbow, wrist and hand. 6.8 Practical sports and medicine

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Book SynopsisSports concussions make headlines, but you don't have to be an NFL star to suffer traumatic brain injury. In Shaken Brain, Elizabeth Sandel, MD, shares stories and research from her decades treating and studying brain injuries. She explains what concussions do to our bodies, how to avoid them, and how to recover.Trade ReviewA fascinating page turner. Propelled by Dr. Sandel’s exceptional storytelling and clinical expertise, Shaken Brain sheds light on the myths and misunderstandings surrounding concussions, and their consequential impact on so many lives. -- Marilyn Spivack, cofounder and past President, Brain Injury Association of AmericaA thoroughly engaging and enlightening account, this book explores the often perplexing issues and controversies surrounding post-concussion symptoms. A vital read. -- Mel Glenn, MD, Spaulding Rehabilitation NetworkI was a doctor in 2002 when I suffered a traumatic brain injury. Even in my position, it was difficult to find information about post-concussive consequences and care. Shaken Brain fills in the gaps. Uniting clinical research, scientific data, and personal stories, this crucial resource is one that both physicians and their patients can look to for answers. -- Cheryle Sullivan, MD, author of Brain Injury Survival KitThe first step to improving concussion care is improving concussion education. Whether you’re an athlete, a parent, a medical professional, or none of the above, having the proper knowledge about what a concussion is and what to do when one is sustained can often be the difference between a quick recovery and a lengthy one. A book like Shaken Brain offers needed information. -- Brittni Souder, former soccer player and Board Member, PINK ConcussionsShaken Brain is frank, accessible, and authoritative—a crucial tool for sharing medical knowledge. Read this book if you are a traumatic brain injury survivor, a clinician, a family member, or simply interested in learning more about brain health. -- David Cifu, MD, Virginia Commonwealth University School of Medicine and the US Department of Veterans AffairsA physician with over 25 years’ experience studying and treating concussion details what happens in the human brain when it is injured, and how medical providers can help…Emphasizing that it isn’t just athletes who need to worry, Sandel examines the high incidence of concussion among certain vulnerable populations, including the very young, elderly, homeless or impoverished, and victims of child abuse or domestic violence. To that end, she looks at prevention as a public health issue…Her expertly presented and researched work will be invaluable for anyone concerned about concussions. * Publishers Weekly *I recommend Shaken Brain to anyone interested in a deeper, nuanced understanding of concussion/mild TBI. Dr. Sandel effortlessly conveys the information typically found in a textbook with the ease and style of a novelist. It is a valuable resource for patients who have experienced concussion and their families, as well as for the physicians, therapists, and scientists who have made it their life’s work to help them. -- John Leddy * Brain Injury *

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Book SynopsisIn the 1980s, a research team led by Parisian scientists identified several unique DNA sequences, or haplotypes, linked to sickle cell anemia in African populations. This title traces how this genetic discourse has blotted from view the roles that Senegalese patients and doctors have played in making sickle cell 'mild' in a social setting.Trade ReviewWinner of the 2014 Robert B. Textor and Family Prize for Excellence in Anticipatory Anthropology, American Anthropological Association Winner of the 2011 Amaury Talbot Prize for African Anthropology, Royal Anthropological Institute "Duana Fullwiley has produced an extraordinary work that incorporates the insights of anthropology as well as science and technology studies of genetics and race. It is also exceptional in its multi-sited focus on Senegal and France, since many similar studies of genetics have tended to focus on the US and Europe."--Elisha P. Renne, Anthropological Quarterly "The Enculturated Gene is the product of over ten years of research beginning in the late 1990s. The book is stunning in its scope and attention to a full range of issues, from discoveries in the lab to knowledge production in the clinic to global health responses... By elucidating ethnographically the contingencies that have produced the local and global health responses to sickle cell disease, Fullwiley shows us that health policy is as much a product of culture and subjectivity as affective responses to physical and existential pain."--Carolyn Rouse, Medical Anthropology QuarterlyTable of ContentsList of Illustrations viii Preface ix Acknowledgments xxv Chapter One: Introduction: The Powers of Association 1 Chapter Two: Healthy Sicklers with "Mild" Disease: Local Illness Aff ects and Population- Level Eff ects 45 Chapter Three: The Biosocial Politics of Plants and People 77 Chapter Four: Attitudes of Care 119 Chapter Five: Localized Biologies: Mapping Race and Sickle Cell Difference in French West Africa 158 Chapter Six: Ordering Illness: Heterozygous "Trait" Suff ering in the Land of the Mild Disease 197 Chapter Seven: The Work of Patient Advocacy 221 Conclusion: Economic and Health Futures amid Hope and Despair 250 Notes 275 References 307 Index 329

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Book SynopsisTrade Review"Winner of the 2018 Don K. Price Award, Science, Technology & Environmental Politics Section of the American Political Science Association""Winner of the 2018 Louis Brownlow Book Award, National Academy of Public Administration""Persuasive."---Carey Goldberg, WBUR's CommonHealth blog"The United States stands out among rich countries in resisting evidence-based medicine--not in theory, perhaps, but in practice. In this informative book, the authors, all political scientists, document this phenomenon and then consider why ordinary people, physicians, and politicians all resist public spending on research that would produce obvious benefits for everyone."---Richard N. Cooper, Foreign Affairs"Unhealthy Politics connects the dots in the complex relationships among physicians, medical societies, the public, and politicians. . . . Unhealthy Politics, in the end, is most convincing in describing the limited extent to which evidence can guide the activities of key actors. The irony is this: For those who wish to see evidence-based medicine implemented, more and better medical evidence might not be the answer. Rather, we need better evidence about how to implement what we already know."---Romana Hasnain-Wynia, Health Affairs"A remarkable example of the contribution that political science has to make to discussions of policy problems that have chiefly concerned other fields . . . . Patashnik, Gerber, and Dowling bring to bear not only a wealth of original survey evidence . . . but also a wealth of theoretical insights from the policy process and legislative politics literatures." * Journal of Politics *

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Book SynopsisThis enlightening and individualistic narrative traces the development of the BMA from its inception, through two world wars and the advent of the NHS

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Book SynopsisCovering both the pharmacological and the more controversial non-pharmacological management of pain relief, this comprehensive text, edited by an internationally renowned specialist, provides practical guidance to all involved in this aspect of labour care.

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Book SynopsisReviews various aspects of the investigation of neurological disease. This book features topics including: Neuropsychological assessment; Vision; Visual loss; Eye movements; Disorders of balance; Peripheral neuropathy; and, Muscle disease. It is intended as a reference for neurologists, neurosurgeons, and psychiatrists.Table of ContentsContributors; Introdution, R.A.C Hughes; Electroencephalography, C.D. Binnie, P.F. Prior; Imagining the head: the brain, Dr I. Mosley; Imagining the head: blood vessels, Dr. R. Sellar; Imagining the head: PET, Dr G.V. Sawle; Imagining the spinal cord, Dr J.M. Stevens; Intracranial pressure, Professor J.D. Pickard; Cerebrospinal fluid, Dr E.J. Thompson; Encephalography, Dr C. Binnie; Neuropsychological testing, Professor E. Warrington; Neuro-ophthalmology - visual disorders, Mr. M. Sanders; Neurotology, including eye movement disorders, Professor C. Kennard; Vestibulocerebellar abnormality, Dr A. Bronstein, Dr P. Rudege; Investigating peripheral neuropathy, Professor J.G. McLeod; Investigating muscle disease, Dr B.R.F. Lecky; Neurogenic bladder, Dr. C. Fowler; Metabolic disorders, Dr P.D. Swanson; Cerebrospinal fluid, E.J. Thompson; Multimodalmonitoring in neurointensive care, P.J. Kirkpatrick, M. Czosnyka, J.D. Pickard; Index

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Book SynopsisThis third, fully revised edition, brings the reader up to date with recent advances made in the study of disease at the molecular and cellular level, and examines the new possibilities for treatment. Subjects covered include methods used in molecular medicine and the polymerase chain reaction.Table of ContentsMolecular and cell biology in clinical medicine; methods in molecular medicine; the polymerase chain reaction - a tool for molecular medicine; an introduction to cells; stem cells in normal growth and disease; cell reproduction; apoptosis (programmed cell death); cell to cell and cell to matrix adhesion; how do receptors at the cell surface transmit signals to the cell interior?; membrane traffic, from cell to clinic; cytoskeleton and disease; the cell nucleus' gene regulation and transcription factors; genes and cancer; human congenital malformations - insights from molecular genetics; molecular genetics of common diseases; impact of molecular biology on clinical genetics; monoclonal antibodies in medicine; production and use of therapeutic agents; gene therapy.

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Book SynopsisTransport affects everyone - it enables access to social activities, employment, leisure, goods, and services. This report highlights the various ways in which transport policy affects health, considering not the more obvious effects but also other consequences of transport policy. It is for students, policy makers, town planners, and doctors.Table of ContentsIntroduction. Patterns of transport use in Great Britain. The health benefits of road transport policy. The health impact of road transport. Reducing health risks and increasing health benefits through transport policy. Towards road transport and health. References. Index.

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Book SynopsisA book which discusses the role of narrative in medicine from various angles, covering both theoretical and practical aspects. It includes real examples of patients' narratives, the use of narrative as a therapeutic tool, teaching narrative to students and the narrative medical record. It is aimed at General Practitioners and medical educators.Trade Review"Add NBM to your EBM and discard your medical mythology" - Journal of the Royal Society of MedicineTable of ContentsIntroduction. 1.Why study narrative?. 2.Turtles all the way down. Illness stories. 3.Themedian isn't the message. 4.The night my life changed. 5.The good bleed guide. 6.Stories of dying. 7.Have i got epilepsy or has it got me?. Filler: the conker tree. Narrative in medicine. 8.Pain narratives. 9.Following hte story: continuity of care in general practice. 10.Narrative and mental health. 11.Sirens, stray dogs and the narrative of hilda thomson. 12.The surgeon's narrative. Filler: pressuring mrs thomas to accept her treatment. Learning and teaching narrative. 13.Literature in medicine. 14.Teaching humanities in the undergraduate medical curriculum. 15.The golden narrative in british medicine. 16.Nursing, narrative and the moral imagination. Filler: Upwardly mobile. Understanding narrative in health care. 17.Stories that we hear and stories we tell. 18.Narrative in psychotherapy. 19.The narrative in medical record. 20.Anecdote in clinical practice. Filler: Dead notes. Broader perspectives on narrative in health care. 21.Narrative in medical ethics. 22.Cross cultural medical narratives: some case studies from latvia and siberia. 23.The narrative stream in medical negligence. 24.Narrative based medicine in an evidence based world. Filler: Dear tom

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Book SynopsisA comprehensive text from the leading transplant centres on the medical management of thoracic organ transplantation, covering the assessment of patients for possible transplantation, through to managing patients after transplantation including any possible complications and shared care aspects of long term managementTable of ContentsIdentification of the suitable heart transplant recipient. Identification of the suitable lung transplant recipient. Medical management of the potential donor. Cardiac transplantation. Choice of procedure and early post-operative management of the lung transplant recipient. Microbiology aspects of heart and heart-lung transplantation. Histopathology of heart and lung transplantation. General management of the heart transplant recipient. Cardiac complications following cardiac transplantation. General management of the lung recipient including aspects of postoperative shared care

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Book SynopsisThe aim of this work is to reduce the risks of medical treatment and enhance the safety of patients in all areas of healthcare. The first section discusses the incidence of harm to patients, while other sections examine features of the healthcare systems that are essential to safe practice.Trade Review"Recommended for all in health care because safety has always been an issue." (Eye News, 2011) "Therefore I believe that this book should be read by anyone involved in, or responsible for healthcare . . . This makes a compelling case to benefit from the safety and quality improvement approaches described in the book." (The Bulletin of the Royal College of Pathologists, 1 July 2011)Table of ContentsUnderstanding adverse events. Errors and adverse events in medicine. The development of risk management. Clinical governance. Reducing risks in obstetrics. Reducing risks in paediatrics. Risk management in anaesthesia. Risk management in surgery. Risk management in A&E medicine. Reducing risks in hospital general medicine. Risk management in clinical oncology. Risk management in psychiatry. Risk management in general practice. Communicating risk. Guidelines and pathways. The role of human factors engineering. Working time, stress and fatigue. Training and supervision. Teams, culture and managing risk. Creating and maintaining safe systems. Impementation of risk management. Clinical incident reporting. Investigation and analysis of adverse events. Caring for patients harmed by treatment. Supporting staff. Dealing with complaints. Resolving disputes. Claims management

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Book SynopsisThe first sustained UK textbook devoted to the newly-emerging Medical Humanities Focusing on the human experiences at the heart of medical care, health, illness, disability and suffering Exploring aspects of clinical medicine which are not captured by natural sciences Integrating a range of contributing humanities disciplines.Table of ContentsSection 1: Humanities Reflecting Society. The nature and role of the medical humanities. Society, community, well being. Evaluating the outcome of arts and health initiatives. Medical record as catalogues of experience. Section 2: Patients and Professionals. The consultation as Rubik's cube. The new genetics - re-telling and re-interpreting an old story. Poetry as a key for healthcare. Spirituality as an integral part of care. Section 3: Changing Attitudes. Portfolio learning. Creative arts in the medical curriculum. Memorials. Why medical humanities now?. Medical humanities - means, ends and evaluation. Section 4: Understanding Medical Knowledge. Validating the facts of experience in medicine. The humanities role. Philosophy's gaze

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Book SynopsisThis book provides a practical set of rules to guide and help trainee obstetricians and midwives to understand the concepts of labour ward management, treatments, and prevention of complications. Labour ward management is a vital tool in learning to secure safe outcomes for both mothers and babies.Table of ContentsIntroduction. Stages of Labour. Fetal Monitoring. Induction of Labour. Operative Deliveries. Complex Deliveries. - Breech Deliveries. - Twin Deliveries. - Shoulder Dystocia. - Preterm Deliveries. Obstetric Haemorrhage and Shock. Infection. Hypertension. Postnatal Problems. Conclusions

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Book SynopsisThis is a workbook for health professionals working with diabetic patients. It is based on the experiences of one group of health care workers in an inner city area. It illustrates how using individual patients'' stories can inform and help health care workers to understand and manage their patients'' difficulties better. In this way it has similar aims to the narrative based medicine books. It also provides the interactive learning element with suggested learning objectives, assignments and further reading in each unit.Table of ContentsAcknowledgements. Introduction. About this workbook. About the Diabetes Sharing Stories Project. About storytelling. About learning in groups. Group work objectives. Unit 1 Learning about diabetes care - where should we start?. Unit 2 The diagnosis of diabetes. Unit 3 Diabetes in the family. Unit 4 Check-ups and visits to the doctor. Unit 5 Medication. Unit 6 Supporting positive lifestyle choices. Unit 7 Loneliness and lack of support. Unit 8 Communicating across cultures. Unit 9 Educating and supporting other health professionals. Unit 10 Diabetes and women's health. Appendix: Template for writing up a story. Index.

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Book SynopsisGeneral practitioners and other primary care professionals have a leading role in contemporary health care, which Trisha Greenhalgh explores in this highly praised new text.Trade Review"Trish Greenhalgh is one of the international stars of general practice and a very clever thinker. This new book is a wonderful new resource for primary health care and general practice. Every general practice registrar should read this book and so should every general practice teacher and every primary care researcher."—Professor Michael Kidd, Head of the Department of General Practice, The University of Sydney and Immediate Past President of The Royal Australian College of General Practitioners "General practice in the U.K. is responsible for more patient care than ever before, and its input to medical training and research is at an all-time high. But its broadening roles and changing political context are at risk of causing an identity crisis. We are fortunate that Professor Trish Greenhalgh has brought her passion, intelligence and scholarship to bear on one of the key questions for health professionals today - what is the best of primary care about, and why is it essential for patients and doctors? She encourages debate while supporting and inspiring primary care, because she tells a modern story of a discipline whose purpose is valuable and which can rise to its new challenges. I am personally very glad to have read this timely and exciting book."—Amanda Howe, MA MD MEd FRCGP ILT(M), Professor of Primary Care & MB/BS Course Director Institute of Health University of East Anglia Norwich NR4 7TJ Norfolk "This book meets a real need for a lively, engaging and perceptive book that brings together the population with the individual perspective and describes the key concepts that underpin contemporary primary care with admirable clarity. This book deserves to become a classic and will be welcomed by enquiring undergraduates and postgraduates alike who want a book that will both challenge and inform."—Professor Andy Haines, Director, London School of Hygiene & Tropical Medicine, London, UK "This important new book by one of primary care's most accomplished authors sets out clearly the academic basis for further developments in primary health care. Health systems will only function effectively if they recognise the importance of high quality primary care so I strongly recommend this book to students, teachers, researchers, practitioners and policy makers."—Professor Martin Marshall, Deputy Chief Medical Officer, Department of HealthTable of ContentsAcknowledgements. Preface. Foreword. 1 Introduction. 1.1 What is primary (health) care? 1.2 What is academic study?. 1.3 What are theories – and why do we need them? 2 The 'ologies' (underpinning academic disciplines) of primary health care. 2.1 Biomedical sciences. 2.2 Epidemiology. 2.3 Psychology. 2.4 Sociology. 2.5 Anthropology. 2.6 Literary theory. 2.7 Philosophy and ethics. 2.8 Pedagogy. 3 Research methods for primary health care. 3.1 What is good research in primary health care? 3.2 Qualitative research. 3.3 Quantitative research. 3.4 Questionnaire research. 3.5 Participatory ('action') research. 3.6 Research data – and analysing it. 3.7 Critical appraisal of published research papers. 3.8 Systematic review. 3.9 Multi-level approaches to primary care problems. 4 The person who is ill. 4.1 The sick role. 4.2 The illness narrative. 4.3 Lifestyle choices and 'changing behaviour'. 4.4 Self-management. 4.5 Health literacy. 5 The primary care clinician. 5.1 The role of the generalist. 5.2 Clinical method I: rationalism and Bayes' theorem. 5.3 Clinical method II: humanism and intuition. 5.4 Clinical method III: the patient-centred method. 5.5 Influencing clinicians’ behaviour. 5.6 The ‘good’ clinician. 6 The clinical interaction. 6.1 The clinical interaction I: a psychological perspective. 6.2 The clinical interaction II: a sociolinguistic perspective. 6.3 The clinical interaction III: a psychodynamic perspective. 6.4 The clinical interaction IV: a literary perspective. 6.5 The interpreted consultation. 7 The family – or lack of one. 7.1 Family structure in the late modern world. 7.2 The mother–child relationship (or will any significant other do these days?) 7.3 Illness in the family – nature, nurture and culture. 7.4 Homelessness. 8 The population. 8.1 Describing disease in populations. 8.2 Explaining the ‘causes’ of disease. 8.3 Detecting disease in populations. 8.4 'Risk': an epidemiological can of worms? 9 The community. 9.1 Unpacking health inequalities I: deprivation. 9.2 Unpacking health inequalities II: social networks and social capital. 9.3 Unpacking health inequalities III: life course epidemiology and 'risk regulators'. 9.4 Developing healthy communities I: community oriented primary care. 9.5 Developing healthy communities II: participatory approaches. 10 Complex problems in a complex system. 10.1 Illness in the twenty-first century: chronicity, comorbidity and the need for coordination. 10.2 Coordinating care across professional and organisational boundaries. 10.3 The electronic patient record: a road map for seamless care? 10.4 The end of an era? 11 Quality. 11.1 Defining and measuring quality. 11.2 A rational biomedical perspective: evidence-based targets, planned change and criterion-based audit. 11.3 A narrative perspective: significant event audit. 11.4 A social learning perspective: peer review groups and quality circles. 11.5 A phenomenological perspective: the patient as mystery shopper. 11.6 A sociological perspective: Quality Team Development as organisational sensemaking. Index

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Book SynopsisExplores the intellectual basis of narrative in medicine. This book provides an interface between evidence based and patient centred medicine.Table of Contents1. The ethicality of narrative medicine. 2. Soldiers become casualties: doctor's accounts of the SARS epidemic. 3. Poems from the heart: living with heart failure. 4. performance narratives in the clinical world. 5. "I cut because it helps": narratives of self injury. 6. The DIPex project: collecting personal experiences. 7. Narratives of spirituality and religion in the end-of-life care. 8. The death of the narrator. 9. Narrative, emotion and understanding. 10. The voice of experience and the voice of the expert - can they speak to each other?. 11. Wounded or warrior? Stories of being or becoming deaf. 12. Narrative analysis and contested allogations of Munchausen syndrome by proxy. 13. Confounding the experts: the vindication of parental testimony in shaken baby syndrome. 14. Narratives of compound loss: parents' stories from the organ retention scandal. 15. The power of stories over statistics: lessons form neonatal jaundice and infant airplane safety. 16. Narratives of health inequality: interpreting the determinants of health. 17. Narratives of displacement and identity. 18. A thrice-told tale: new readings of an old story. 19. The role of stories and storytelling in organisational change efforts: a field study of an emerging "community of practice" within the UK National Health Service. 20. Meta-narrative mapping: a new approach to the systematic review of complex evidence. 21. How narratives work in psychiatric science: an example from the biological psychiatry of PTSD. 22. Storytelling policy: constructions of risk in proposals to reform UK mental health legislation. 23. The temporal construction of medical narratives

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Book SynopsisBrings you up to speed on recognising the symptoms of serious illnesses. This book provides information on diagnosis and action. It answers the express need of doctors to avoid making diagnostic errors.Trade Review"A must have [that] will surely come in handy, even if it saves just one patients life in the future.... Overall grade/score: 5/5." (Leicester Scrubs, January 2010) "This is a valuable and well-edited collection of potentially serious speciality-specific symptoms. It is highly informative and should alert the reader to the 'alarm bells' that may present in their clinical practice. The book should prove a valuable asset to the library of anyone involved in the practice of medicine including medical students, GPs and hospital doctors." (Annals Royal College of Surgeons of England, 2006)Table of ContentsList of contributors. Introduction. Acknowledgement. Abbreviations. Breast surgery. Cardiology. Cardiothoracic surgery. Care of the elderly. Dermatology. Endocrinology. ENT. Gastroenterology and colorectal surgery. Genito-urinary medicine. Gynaecology. Haematology. Heptology and hepatobiliary surgery. HIV medicine. Immunology. Metabolic medicine. Neurology. Neurosurgery. Obstetrics. Oncology. Ophthalmology. Oral and maxillofacial surgery. Orthopaedics. Paediatrics. Paediatric surgery. Plastic surgery. Psychiatry. Renal medicine. Respiratory medicine. Rheumatology. Transplantation. Upper GI surgery. Urology. Vascular surgery. Index

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Book SynopsisA detailed guide to the clinical trial process Content designed in consultation with doctors and patients who have taken part in trials Helps workers to discuss the pros and cons of participation with patients Allows patients to make well-informed decisions on whether to take part in a clinical trial.Table of ContentsChapter 1 Overview and Purpose of this Guide to Clinical Trials in the NHS. Overview and purpose of this guide. Who should use this guide to clinical trials in the NHS?. Chapter 2 Clinical Trials Explained. What are clinical trials?. Why are clinical trials needed?. Who is involved in a clinical trial?. How are clinical trials designed and approved?. Progression of a medical intervention through the clinical trial phases. Summary. Chapter 3 Clinical Trial Approval, Regulation and Funding. How are clinical trials approved and regulated?. Ethical approval. Informed consent. How are trials managed?. Who pays for a clinical trial?. Summary. Chapter 4 Understanding Clinical Trial Design and Results. Understanding randomisation and blinding in clinical trials. Understanding controls and placebos. Why are placebos used in clinical trials?. What about trials that are not controlled or blinded?. Understanding clinical trial results. Summary. Chapter 5 Questions About Clinical Trials: A Framework for Discussion. What are patients’ rights?. Why do patients take part in clinical trials?. Why do patients decline to take part in a clinical trial or withdraw from a clinical trial they are involved in?. How can patients be empowered during their involvement in a. clinical trial?. Will patients involved in clinical trials need extra help and support from. their carers?. What are the likely costs of and reimbursement for patients participating. in clinical trials?. Summary. Appendix A Finding Out About Clinical Trials that are Currently or Soon to be Recruiting. Appendix B ECRI Evidence Report: Patients’ Reasons for Participation in Clinical Trials and Effect of Trial Participation on Patient Outcomes. Glossary. Index

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Book Synopsis* A thoughtful and insightful textbook introduction to how health policy is made. * Pays attention to the social and political processes which structure what decisions are taken about health policy.Trade Review"This readable and accessible book provides many novel insights into the policy-making process, a broad span of well-chosen historical and contemporary health examples, and a range of perspectives to consider in relation to the analysis of health policy making."Health Sociology Review"This introductory text offers a novel approach to health policy making, challenging the conception of policy as a rational process. Written in an accessible style it is essential reading for undergraduate students of health policy."Jonathan Gabe, Royal Holloway, University of London "This book should be essential reading for any student interested in engaging with and critically reflecting on how health policy is shaped in contemporary society. Drawing on well chosen historical and contemporary examples, Making Health Policy engages with the complex, contingent, and contested arena of health policy making. Students will find the valuable insights provided in this book enormously useful in understanding contemporary and ongoing debates around the fashioning of health policy."Nick Emmel, University of Leeds "Alaszewski and Brown's historical reach and deep understanding of health policy going back 30 years makes this a highly readable, original, insightful and well-informed study that also manages to be remarkably up-to-date. Recommended reading for everyone interested in how health policy gets made and why it doesn't always happen as intended."David J. Hunter, Durham UniversityTable of ContentsPreface Introduction 1. What is health policy? Part 1 Rationality in policy making 2. Trying to achieve rational health policy: the search for appropriate knowledge and expertise 3. The competition for money and the limits of instrumental rationality 4. Power and influence in policy making: Policy communities and networks 5. The pressure of events: Disasters, inquiries and the dynamics of blame Part 2 The limits of rationality in policy making 6. Identifying health and social problems: Competition between interest groups and claims making 7. How does the nature of modern democracy shape the formation of health policy? 8. Ideology and policy: legitimating, bounding and framing 9. The impact of the media on health policy making Part 3 Conclusion 10. So how and why are health policies made? Some final comments References

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Book SynopsisSteadily increasing numbers of Americans have been diagnosed with asthma in recent years, attracting the attention of biomedical researchers, including those searching for a genetic link to the disease. The high rate of asthma among African American children has made race significant to this search for genetic predisposition. One of the primary sites for this research today is Barbados. The Caribbean nation is considered optimal because of its predominantly black population. At the same time, the government of Barbados has promoted the country for such research in an attempt to take part in the biomedical future.In Biomedical Ambiguity, Ian Whitmarsh describes how he followed a team of genetic researchers to Barbados, where he did fieldwork among not only the researchers but also government officials, medical professionals, and the families being tested. Whitmarsh reveals how state officials and medical professionals make the international biomedical research part of state caTrade ReviewWhitmarsh's investigation compels a rethinking of the biomedical stabilization of race and of enigmatic illnesses like asthma. His insight into the process by which race, genes, and environmental factors are negotiated in the Caribbean at the request of large corporations and scientific research teams is important. It will help the reader understand how such ideas, practices, and drugs are being marketed worldwide. -- Malcolm N. Blumenthal, MD * New England Journal of Medicine *

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Book SynopsisWhen Your Spouse Has a Stroke will relieve your burden and strengthen your partnership.Trade ReviewThis book is unique and clearly needed by many families of stroke survivors. -- Andreas R. Luft CardioPulse This book is a treasure that each caregiving spouse can mine for helpful suggestions and better ways of handling the kinds of issues we all face. -- Sandra M. Fowler PsycCRITIQUESTable of ContentsAcknowledgmentsPrologue: Setting the Stage for Life after StrokeIntroduction: When Stroke Moves In: How Stroke Affects You and Your Marriage1. The Secret Ingredient: Stroke and Social Support2. You Are the One: Balancing the Roles of Caregiver and Marriage Partner3. A Fine Romance: Sex and Intimacy after Stroke4. Give Me a Break: Support for the Caregiving Spouse5. In Sickness and in Health: Rebuilding Your Marriage after Stroke6. 'Til Death Do Us Part: Going the Distance with Your Spouse after StrokeEpilogue: From This Day On: The Future of CaregivingNotesResourcesIndex

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Book SynopsisPrecision medicine is rapidly becoming the standard-of-care for the treatment of cancer patients. Precision Medicine Oncology: A Primer is a concise review of the fundamental principles and applications of precision medicine, and intended for clinicians, particularly those working in the field of oncology.Table of ContentsPreface: Introduction to Precision Medicine Authors: Lorna Rodriguez-Rodriguez, MD, PhD, Kim M. Hirshfield, MD, PhD, Shridar Ganesan, MD, PhD Chapter I: Genomic Technology/Next-Generation Sequencing Authors: Hossein Khiabanian, PhD, Shridar Ganesan, MD, PhD, Kim M. Hirshfield, MD, PhD, Gregory Riedlinger, MD, PhD, Chapter II: The Precision Medicine Oncology Molecular Tumor Board: Interpreting and Applying Precision Medicine to Patient Care Authors: Shridar Ganesan, MD, PhD, Kim M. Hirshfield, MD, PhD, Gregory Riedlinger, MD, PhD, Lorna Rodriguez-Rodriguez, MD, PhD Chapter III: Clinical Research in Precision Medicine Oncology Authors: Kim M. Hirshfield, MD, PhD, Shridar Ganesan, MD, PhD Chapter IV: Infrastructures in Precision Medicine Oncology: Biobanks, Biomedical Informatics, and Big Data Authors: Shridar Ganesan, MD, PhD, Kim M. Hirshfield, MD, PhD Chapter V: Future Directions in Precision Medicine Oncology Authors: Shridar Ganesan, MD, PhD, Kim M. Hirshfield, MD, PhD, Lorna Rodriguez-Rodriguez, MD, PhD

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Book SynopsisThis book addresses consequences on the cardiovascular system that arise from iatrogenesis— the occurrence of untoward effects resulting from actions of health care providers, including medical errors, medical malpractice, practicing beyond one’s expertise, adverse effects of medication, unnecessary treatment, inappropriate screenings, and surgical errors.Table of ContentsTABLE OF CONTENTS Part I: MEDICAL HARM 1. The Concept and Spectrum of "Iatrogenicity" I. Gussak and J. Kostis 2. Iatrogenicity: Definition, History and Modern Context M. Gussak, I. Gussak, and J. Kostis 3. Epidemiology and Public Health Aspects and Implications: Regulatory, Legal and Ethical Dimensions of Iatrogenicity S. Jones and M. Gonzalez 4. Risk Management: The Medical Center Administration Perspective S. Jones and M. Gonzalez 5. Iatrogenicity from the Patient's Perspective J. Dobrzynski, S. Jones, and M. Gonzalez 6. A Naturopathic Perspective on Iatrogenesis C. Fleetwood Part II: IATROGENICITY OF CARDIOVASCULAR DURGS AND CARDIOVASCULAR TOXICITY OF NON-CARDIAC DRUGS 7. Clinical Manifestations of Acute and Chronic Drug-Induced Iatrogenic Cardiovascular Diseases and Syndromes I. Gussak, G. Yan, A. Jahangir, and J. Kostis 8. Drug-Induced Cardiac Arrhythmias and Sudden Cardiac Death A. Narichania, Y. Yokoyama, and W.K. Shen 9. Chemotherapy-Induced Cardiomyopathies E. Birati and B. Jessup 10. Iatrogenicity of Blood Pressure Mesaurement in the Diagnosis of Hypertension T. Giles, G. Sander, I. Gussak, and J. Kostis 11. Antihypertensive Drug-Induced Iatrogenic Cardiovascular Syndromes R. Kalaitzidis and G. Bakris 12. Iatrogenicity of Cardiovascular Drugs Associated with Cardiac and Non-Cardiac Toxicities: Antihypertensive Agents and Biologics E. Hermes-Desantis and J. Barone 13. Iatrogenic Aspects of Hypertension in Pregnancy: Focus on Preeclampsia C. Thomopoulos and T. Makris 14. Women and Iatrogenic Cardiovascular Disease: Menopausal Estrogen as the Prime Suspect G. Bachmann, M. Rees, and N. Phillips 15. Iatrogenic Aspects of Lipid-Lowering Agents, Thrombolytic, Antiplatelet, and Antithrombotic Agents C. Tsioufis, D. Konstantinidis, N. Vogiatzakis, and K. Dimitriadis 16. Iatrogenic Effects of ‘Urologic' Drugs on the Cardiovascular System K. Stavropoulos, C. Boutari, K. Imprialos, and M. Doumas 17. Iatrogencity and Antianginal Drugs A. Moreyra and W.J. Kostis 18. Anti-Diabetic Drugs and Cardiovascular Risk: Where Do We Stand? R. Kumar 19. Cardiovascular Iatrogenicity in Older Adults A. Khan, #. Ali, #. Iyengar, #. Hagiwara, #. Periyakoil, #. Patel, #. Malone Part III: IATROGENCITY OF DIAGNOSTIC AND THERAPEUTIC, INVASIVE AND NON-INVASIVE CARDIOVASCULAR INTERVENTION, DEVICES, AND SURGERIES 20. Iatrogenic Aspects of Non-Invasive and Invasive Diagnostic Methods in Interventional Cardiology C. Dösch, D. Loßnitzer, T. Papavassiliu 21. Iatrogenicity Associated with Interventional Treatment Modalities N.V. Pothineni, A. Garg, H. Paydak, and J.L. Mehta 22. Iatrogenicity of Diagnostic and Therapeutic, Invasive and Non-Invasive Cardiovascular Interventions, Devices and Surgeries M. Behnes, T. Becher, S. Baumann, and I. Akin 23. Iatrogenic Aspects in Cardiac Electrophysiology B. Rudic, E. Tülümen, and V. Liebe 24. Iatrogenic Aspects in Cardiac Device Therapy S. Röger and J. Kuschyk 25. Cardiovascular Iatrogencity of Respiratory Therapeutic Modalities M.S. Nolledo, P. Lerma and T.V. Santiago Part IV: IATROGENIC ASPECTS OF SPORT CARDIOLOGY AND LIFE-STYLE MODIFICATIONS 26. Professional Athletes G. Mancia 27. Sports Cardiology G. Campanile 28. Dangers of Lifestyle Modification Advice G. Campanile Part V: IATROGENICITY OF DIETARY SUPPLEMENTS, HERBAL PRODUCTS, AND OTHER NON-TRADITIONAL THERAPIES IN CARDIOVASCULAR MEDICINE 29. Safety of Over-the-Counter ‘Natural Substances’ and Vitamins: Side-effects and Contraindications S. Sultan, A. Jahangir, C. Ding, H. Cao, J.B. Kostis, I.B. Gussak, and A. Jahangir 30. Interactions Between Supplements and Prescription Medications S. Sultan, A. Jahangir, C. Ding, H. Cao, J.B. Kostis, I.B. Gussak, and A. Jahangir Acknowledgments Index

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Book SynopsisThis book addresses consequences on the cardiovascular system that arise from iatrogenesis— the occurrence of untoward effects resulting from actions of health care providers, including medical errors, medical malpractice, practicing beyond one’s expertise, adverse effects of medication, unnecessary treatment, inappropriate screenings, and surgical errors.Table of ContentsTABLE OF CONTENTS Part I: MEDICAL HARM 1. The Concept and Spectrum of "Iatrogenicity" I. Gussak and J. Kostis 2. Iatrogenicity: Definition, History and Modern Context M. Gussak, I. Gussak, and J. Kostis 3. Epidemiology and Public Health Aspects and Implications: Regulatory, Legal and Ethical Dimensions of Iatrogenicity S. Jones and M. Gonzalez 4. Risk Management: The Medical Center Administration Perspective S. Jones and M. Gonzalez 5. Iatrogenicity from the Patient's Perspective J. Dobrzynski, S. Jones, and M. Gonzalez 6. A Naturopathic Perspective on Iatrogenesis C. Fleetwood Part II: IATROGENICITY OF CARDIOVASCULAR DURGS AND CARDIOVASCULAR TOXICITY OF NON-CARDIAC DRUGS 7. Clinical Manifestations of Acute and Chronic Drug-Induced Iatrogenic Cardiovascular Diseases and Syndromes I. Gussak, G. Yan, A. Jahangir, and J. Kostis 8. Drug-Induced Cardiac Arrhythmias and Sudden Cardiac Death A. Narichania, Y. Yokoyama, and W.K. Shen 9. Chemotherapy-Induced Cardiomyopathies E. Birati and B. Jessup 10. Iatrogenicity of Blood Pressure Mesaurement in the Diagnosis of Hypertension T. Giles, G. Sander, I. Gussak, and J. Kostis 11. Antihypertensive Drug-Induced Iatrogenic Cardiovascular Syndromes R. Kalaitzidis and G. Bakris 12. Iatrogenicity of Cardiovascular Drugs Associated with Cardiac and Non-Cardiac Toxicities: Antihypertensive Agents and Biologics E. Hermes-Desantis and J. Barone 13. Iatrogenic Aspects of Hypertension in Pregnancy: Focus on Preeclampsia C. Thomopoulos and T. Makris 14. Women and Iatrogenic Cardiovascular Disease: Menopausal Estrogen as the Prime Suspect G. Bachmann, M. Rees, and N. Phillips 15. Iatrogenic Aspects of Lipid-Lowering Agents, Thrombolytic, Antiplatelet, and Antithrombotic Agents C. Tsioufis, D. Konstantinidis, N. Vogiatzakis, and K. Dimitriadis 16. Iatrogenic Effects of ‘Urologic' Drugs on the Cardiovascular System K. Stavropoulos, C. Boutari, K. Imprialos, and M. Doumas 17. Iatrogencity and Antianginal Drugs A. Moreyra and W.J. Kostis 18. Anti-Diabetic Drugs and Cardiovascular Risk: Where Do We Stand? R. Kumar 19. Cardiovascular Iatrogenicity in Older Adults A. Khan, #. Ali, #. Iyengar, #. Hagiwara, #. Periyakoil, #. Patel, #. Malone Part III: IATROGENCITY OF DIAGNOSTIC AND THERAPEUTIC, INVASIVE AND NON-INVASIVE CARDIOVASCULAR INTERVENTION, DEVICES, AND SURGERIES 20. Iatrogenic Aspects of Non-Invasive and Invasive Diagnostic Methods in Interventional Cardiology C. Dösch, D. Loßnitzer, T. Papavassiliu 21. Iatrogenicity Associated with Interventional Treatment Modalities N.V. Pothineni, A. Garg, H. Paydak, and J.L. Mehta 22. Iatrogenicity of Diagnostic and Therapeutic, Invasive and Non-Invasive Cardiovascular Interventions, Devices and Surgeries M. Behnes, T. Becher, S. Baumann, and I. Akin 23. Iatrogenic Aspects in Cardiac Electrophysiology B. Rudic, E. Tülümen, and V. Liebe 24. Iatrogenic Aspects in Cardiac Device Therapy S. Röger and J. Kuschyk 25. Cardiovascular Iatrogencity of Respiratory Therapeutic Modalities M.S. Nolledo, P. Lerma and T.V. Santiago Part IV: IATROGENIC ASPECTS OF SPORT CARDIOLOGY AND LIFE-STYLE MODIFICATIONS 26. Professional Athletes G. Mancia 27. Sports Cardiology G. Campanile 28. Dangers of Lifestyle Modification Advice G. Campanile Part V: IATROGENICITY OF DIETARY SUPPLEMENTS, HERBAL PRODUCTS, AND OTHER NON-TRADITIONAL THERAPIES IN CARDIOVASCULAR MEDICINE 29. Safety of Over-the-Counter ‘Natural Substances’ and Vitamins: Side-effects and Contraindications S. Sultan, A. Jahangir, C. Ding, H. Cao, J.B. Kostis, I.B. Gussak, and A. Jahangir 30. Interactions Between Supplements and Prescription Medications S. Sultan, A. Jahangir, C. Ding, H. Cao, J.B. Kostis, I.B. Gussak, and A. Jahangir Acknowledgments Index

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Book SynopsisHaving had the privilege of working throughout Africa, Asia, and Latin America, as well as in the great medical centers of Europe and the United States, the author presents the essential details for understanding pathogenesis, clinical manifestations, therapy, and prevention of the major tropical diseases.Trade Review"Diplomats who must deal with the after-effects of man-made and natural disasters are well aware that epidemic diseases flourish as societies collapse, and that more people usually die in such circumstances from preventable illnesses than from armed conflicts. This is an essential book for those who seek to restore peace and stability in war-torn and disaster areas. It considers the critical interrelationships of medicine and statesmanship, and it is one of the reasons why I have asked the author to serve as my Chief Adviser on Humanitarian and Public Health issues." -- -H.E. Nassir Al Nasser President, United Nations General Assembly, Sixty-sixth Session "This revised and expanded edition of Tropical Medicine: A Clinical Text reflects the personal experience of the author over many years of direct and intimate contact with countries in the Third World, ranging from those in Africa to those in South America. It has been the standard textbook used by many generations of both medical students and postgraduate physicians studying tropical medicine at the Royal College of Surgeons in Ireland and in other academic centers around the world. It is a practical and very readable textbook." -- -Herbert Gilles, M.D., C.M.G. Professor Emeritus, The Liverpool School of Tropical Medicine; Past President, The Royal Society of Tropical Medicine and Hygiene "... A 'must' for any medical collection. It provides a world history of tropical medicine approaches and comes from a doctor who himself has worked throughout the world in both Third World and developed countries." -California Bookwatch

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Book SynopsisFrom its initial clinical use, over 28 years ago, to its current extensive use (over 100,000 times annually in the US alone), balloon pump equipment has developed into sophisticated, computer--assisted technology for mechanically aiding circulation.Trade Review"...well written and well organized. It should be welcome as a reference text to the libraries of multidisciplinary teams caring for cardiac patients." --Canadian Journal of Surgery "This book presents a comprehensive and up to date review of the use of the intra-aortic balloon pump (IABP) ...The sections on balloon pump equipment, consoles and catheters, and the physiology of balloon pumping are all particularly good, and perhaps should be mandatory reading for all trainees in cardiac surgery, cardiac anesthesia, invasive cardiology and clinical perfusion. "It is a worthwhile addition to the library of a busy cardiovascular critical care unit in which IABPs are used frequently, and is a good reference text for anyone who is considering research involving the IABP." --Canadian Journal of AnesthesiaTable of ContentsSection I: Assisted Circulation. 1. The Principle of Circulatory Assist. 2. Pulsatile Assist Devices and Counterpulsation. Section II: Cardiac Function and Pathophysiology of Cardiac Failure. 3. Cardiac Function and Classification Of Cardiac Failure. 4. Cardiogenic Shock. Section III: The Intra-Aortic Balloon Pump. 5. Historical Background. 6. Balloon Pump Equipment. 7. Balloon Pump Consoles and Catheters. 8. Physiology of Balloon Pumping. 9. General Criteria, Contraindications and Guidelines for Balloon Pumping. 10. Methods of Insertion and Removal of Intra-Aortic Balloon Catheter. 11. Complications of Balloon Pumping. Section IV: Management of Patients on Intra-Aortic Balloon Pump. 12. Nursing Care Of Patients on Intra-Aortic Balloon Pump. 13. Hemodynamic Monitoring, Data Acquisition and Assessment of Efficacy of Diastolic Augmentation. 14. Pharmacologic Treatment. 15. Management of Patients on Intra-Aortic Balloon Pump in Special Situations. 16. Problems With Use of Balloon Pumping. 17. Weaning from Intra-Aortic Balloon Pump Assist. 18. System Management in Patients on Intra-Aortic Balloon Pump. 19. Ancillary Measures in Care of Patients on Intra-Aortic Balloon Pump. Section V: Indications for Use of Intra-Aortic Balloon Pump. 20. An Overview. 21. Intra-Aortic Balloon Pump for Coronary Artery Disease. 22. Balloon Pumping in Cardiogenic Shock. 22. Balloon Pumping in Cardiac Surgery. 23. Miscellaneous Indications for Balloon Pumping

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