Cardiovascular medicine Books

Book SynopsisThe fundamental premise of lifestyle medicine is that daily habits profoundly impact health and quality of life both in the short-term and long-term. Written by lifestyle medicine pioneer and cardiologist , Dr. James Rippe, this book provides a clinically oriented, evidence-based look into key lifestyle factors and how to prescribe them to individuals of all ages.Written for professionals working at all levels of medical and healthcare practice, this manual summarizes the major components of lifestyle medicine, from physical activity and nutrition to weight management and the avoidance of tobacco products. It includes clinical guidelines and practices for using lifestyle medicine principles to lower the risk of numerous chronic conditions. The manual also provides information on behavior change, approaches to lowering the risk of dementia, treatment of addictions and injury prevention.Features:Explains how lifestyle medicine can reduce the risk of heart disTable of ContentsContents Preface.......................................................................................................................ix Acknowledgments................................................................................................... xiii Author Bio.................................................................................................................xv Chapter 1 Lifestyle Challenges and Opportunities................................................1 Chapter 2 Nutrition in Lifestyle Medicine........................................................... 11 Chapter 3 Physical Activity and Health............................................................... 31 Chapter 4 Behavioral Change.............................................................................. 47 Chapter 5 Lifestyle Medicine and Cardiovascular Disease................................. 61 Chapter 6 Diabetes, Prediabetes, and Metabolic Syndrome................................ 75 Chapter 7 Cancer Prevention and Treatment.......................................................87 Chapter 8 Obesity and Weight Management..................................................... 103 Chapter 9 Pulmonary Medicine......................................................................... 121 Chapter 10 Obstetrics and Gynecology............................................................... 139 Chapter 11 Lifestyle Medicine and Brain Health................................................ 153 Chapter 12 Women’s Heath.................................................................................. 163 Chapter 13 Immunology and Infectious Disease................................................. 177 Chapter 14 Pediatrics........................................................................................... 185 Chapter 15 The Practice of Lifestyle Medicine...................................................203 Chapter 16 Lifestyle Medicine for the Older Adult Population........................... 215 Chapter 17 Heath Promotion...............................................................................223 Chapter 18 Injury Prevention............................................................................... 231 Chapter 19 Substance Abuse and Addiction........................................................ 243 Chapter 20 Public Policy and Environmental Support for Lifestyle Habits and Practices..................................................................................... 257 Chapter 21 Lifestyle Medicine around the World................................................269 Chapter 22 The Future of Lifestyle Medicine..................................................... 279 Index....................................................................................................................... 291

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Book SynopsisTable of ContentsInvasive Pulmonary Angiogram Performance and Interpretation in the Diagnosis of Pulmonary Thromboembolic Disease Catheter-Directed Thrombolysis or Catheter-Based Thrombectomy in Acute Pulmonary Embolism: Horses for Courses Mechanical Circulatory Support and Critical Care Management of High-Risk Acute Pulmonary Embolism Open Surgical Treatment of Acute and Chronic Pulmonary Embolism Cardiopulmonary Exercise Testing, Rehabilitation, and Exercise Training in Postpulmonary Embolism Technical Considerations for Performing Safe and Effective Balloon Pulmonary Angioplasty in Patients with Chronic Thromboembolic Pulmonary Hypertension The Evolution of Pulmonary Artery Denervation for Treatment of Pulmonary Arterial Hypertension Pulmonary Embolism Center of Excellence: Putting It All Together Unmet Needs and Future Direction for Pulmonary Embolism Interventions Evolving Role and Clinical Evidence in the Global Practice of Balloon Pulmonary Angioplasty Outpatient Follow-up of Pulmonary Embolism: Putting It all Together The Intersection of Pulmonary Vascular Disease and Hypoxia-Inducible Factors

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Book SynopsisGive your heart the best chance of carrying on beating for many years to come.Table of ContentsContents: Introduction 71 How your heart works 102 Common symptoms 173 Checking out your heart 234 Chest pain 335 Trouble with valves 496 Electrical problems (arrhythmias) 587 When the muscle malfunctions 698 High blood pressure (hypertension) 759 Looking after your heart 8710 Living with heart disease 99Appendix: Further sources of adviceand information 106

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Book SynopsisWe have all been hypoxic. Fetal tolerance for intrauterine hypoxia arises from evolutionarily conserved physiological mechanisms, the antecedents of which can be learned from diving mammals or species at high altitudes. Understanding fetal hypoxia leads to understanding the huge physiological shifts of neonatal transition and the dangers of perinatal hypoxia.This comprehensive volume of topical review articles by expert authors addresses the origins of hypoxia tolerance, the impact of oxygen on circulatory transition at birth, and the biochemistry of hypoxia in the pulmonary circuit, as well as the classification, diagnosis, and clinical management of hypoxic respiratory failure and persistent pulmonary hypertension in the term neonate.The goal of Hypoxic Respiratory Failure in the Newborn is to connect our understanding of hypoxia from animals in extreme environments, with how the human fetus handles its hypoxic environment; and why the human newborn sudTrade Review'This book elects to follow the thread of hypoxia, as an originating etiology and defining feature of neonatal pulmonary hypertension. It is a comprehensive and thematic volume of topical articles by world renowned authors, and has assembled all information pertinent to this topic in 38 chapters divided into 5 distinct sections, each marshalled by a dedicated co-editor. This strong interdisciplinary editorial team brings to bear complementary theoretical and practical expertise in different aspects of hypoxia and respiratory failure, and clearly a wide-ranging contact list – the book has over 80 contributing authors. Salient features of this book are helpful signaling pathway diagrams, conceptual illustrations, and synthesis figures by Satyan Lakshminrusimha.Reading the whole volume provides a satisfying continuous narrative of hypoxia through the evolutionary and developmental timeline, and deeper insight into what might appear to be only a superficial problem solved by turning up the oxygen dial. This book is therefore recommended to practicing clinicians as much as to scholars in this field of science.'Dr Kurt Stenmark'It is the most comprehensive discussion of this topic to be found anywhere in the literature. […] There are no comparable texts on this subject, although hypoxia and PPHN are discussed in every standard neonatal textbook. The five authors and the over 80 contributors are the world's research leaders in this topic and are to be congratulated on this superb publication.'Jay P. Goldsmith, MD (Tulane University School of Medicine), Doody EnterprisesTable of ContentsTable of Contents1. IntroductionPart 1: The Origins of Hypoxia Tolerance 2. The Human Fetus and Metabolic Adaptations to Hypoxia3. Hypoxia as a Neuroinflammatory Stimulus During Development4. Human Adaptations to High Altitude5. Fetal Llama Adaptation to Altitude in the Andean Altiplano6. Neonates of Burrowing and Hibernating Mammals: Metabolic and Respiratory Adaptations to Hypoxia7. Diving Response and Hypoxia in Deep Sea Mammals8. The Phylogeny and Ontogeny of Cardiorespiratory Coupling in Vertebrates and its Relevance to Non-Invasive Monitoring of the Human FetusPart 2: Fetal Hypoxia and Neonatal Transition9. Fetal and Neonatal Oxygen Environment10. Fetal Oxygenation During Maternal Hypoxic Illness11. Hemodynamics of the Circulatory Transition12. Oxygen During Postnatal StabilizationPart 3: Biology of Hypoxic Respiratory Failure in the Neonate13. Hypoxia and Pulmonary Artery Structure14. Animal Models of PPHN and Vasoconstrictor Signaling in Hypoxia15. Hypoxia and Endothelial Dysfunction in the Lung16. Effects of Hypoxia on Pulmonary Vascular Smooth Muscle Contraction and Relaxation17. Cellular Oxygen Sensing, Mitochondrial Oxygen Sensing and Reactive Oxygen Species18. Reactive Oxygen Species Signaling in Animal Models of Pulmonary Hypertension19. Hypoxia, Myocardial Metabolic Adaptation and Right Ventricular Performance20. Hypoxic Remodeling of Neonatal Pulmonary Artery and Myocardium21. Hypoxia-Induced Epigenetic Mechanisms of Pulmonary HypertensionPart 4: Hypoxia and Collateral Damage22. The Effects of Hypoxia Ischemia on the Term Brain, and A Strategic Approach23. Effects of Hypoxia on Cerebral Perfusion and the Blood-Brain Barrier24. Effects of Hypoxia on Airway, Alveolar Function and Respiration25. Hypoxic Respiratory Failure and the Neonatal Kidney26. The Effect of Hypoxia on Intestinal Function27. Effects of Hypoxia on Perinatal Drug Disposition28. Anesthetic Considerations for the Neonate with Hypoxic Respiratory FailurePart 5: Diagnosis and Management of Neonatal Hypoxic Respiratory Failure29. Epidemiology and Outcomes of Infants with Hypoxemic Respiratory Failure30. Clinical Evaluation of Hypoxic Respiratory Failure31. Diagnosis of Pulmonary Hypertension by Echocardiography32. Right Ventricular Performance and Ventricular Interdependence in Hypoxia33. Ventilation Strategies in Neonatal Hypoxemic Respiratory Failure34. Pulmonary Hypertension Phenotypes in the Newborn35. Special Consideration: HRF in Congenital Diaphragmatic Hernia36. Special Consideration: Hypoxemic Respiratory Failure Among Patients with Hypoxic Ischemic Encephalopathy37. Special Consideration: HRF in the Preterm38. Hypoxemic Respiratory Failure – Neonatal Cases

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Book SynopsisGeriatrics, Lifestyle Medicine and Healthy Aging: A Practical Guide is a book for those interested in promoting healthy aging through lifestyle approaches. The book is divided into three sections covering various aspects of lifestyle medicine for older individuals including general concepts of lifestyle medicine practices; lifestyle âœpillarsâ as applied to older adults; and of a broad range of target conditions of importance to older adults, and how a lifestyle medicine approach may impact them. Readers gain an understanding of how lifestyle medicine and geriatrics can work together to provide a holistic approach that fosters healthy aging throughout life.Features Research-supported analysis of the relevance of lifestyle medicine in geriatric populations. Evidence-based discussion of conditions that impact quality of life in older adults, including sarcopenia, incontinence, bone health, polypharmacy and falls, and how lifestyle medicine can prevent and treat such conditions. Edited by a leading expert in the fields of healthy aging, and lifestyle medicine in older adults.As part of the Lifestyle Medicine series edited by Dr. James M. Rippe, this book is useful to geriatric medicine clinicians who would like to increase the tools in their practice of caring for older adults; lifestyle medicine clinicians who want to understand how to effectively use lifestyle pillars to care for older adults; and anyone who is interested in their own, or a loved oneâs, healthy aging.

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Book SynopsisInterpreting an ECG correctly and working out what to do next can seem like a daunting task to the non-specialist, yet it is a skill that will be invaluable to any doctor, nurse or paramedic when evaluating the condition of a patient.Making Sense of the ECG has been written specifically with this in mind and, across multiple editions, has helped students and more experienced healthcare practitioners to identify and answer crucial questions, including:Are these abnormalities significant?How do I distinguish between VT and SVT?Does this patient have an acute coronary syndrome?How do I measure the QT interval?Should I refer this patient to a cardiologist?This popular, easy-to-read and easy-to-remember guide to the ECG as a tool for diagnosis and management has been fully updated in its sixth edition to reflect the latest guidelines, with new chapters added: âReading an ECG Recordingâ and 'Ten ECGs Not to Missâ.Key features:

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Book SynopsisRehabilitation is an essential part of the healthcare continuum and can benefit both the individual and the community. Physical Medicine and Rehabilitation addresses a vast group of health conditions including neurological, musculoskeletal, and cardiovascular, respiratory cases as well as sensory impairments developmental delays. Patients preparing for surgery, recovering from trauma, or receiving treatment for cancer can all benefit from rehabilitative programs to improve their health outcomes. Athletes and otherwise healthy individuals can also benefit from science of physical and sports medicine to improve performance and recovery time.This book provides a brief introduction to Physical Medicine and Rehabilitation and its historical and global context for readers interested in the role of design. It introduces various settings where rehabilitation can be provided and their relevant patient demographics, influential trends, and available research to paint a full picture for readers who wish to better understand this field. The book lays the groundwork for making design decisions by sharing available standards, project case studies, environment & behaviour literature, and applicable theories. Finally, it provides design and planning guidelines as well as trends that can impact future planning and design of environments that support rehabilitation programs. The book also highlights existing knowledge gaps the in design and planning of rehabilitation environments and provides a framework for environment & behavior researchers who wish to expand the field by addressing needs of patients, staff and families.

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Book SynopsisThere is a disconnect on how health professions perceive and treat the causes of upper airway conditions. Various comorbidities can result from sleep apnea, oxygen deprivation, and upper airway conditions. This book connects oropharyngeal structure to metabolic disease through the practice of teledontics. Teledontics as a new interdisciplinary integrative medical - dental approach for treatment of obstructive sleep apnea is emerging rapidly. It relates oxygen needs of the body in addition to other nutritional requirements focusing on how oxygen insufficiency can lead to multiple health comorbidities.

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Book SynopsisClinical Guide to Cardiology is a quick-reference resource, packed full of bullet points, diagrams, tables and algorithms for the key concepts and facts for important presentations and conditions within cardiology.Table of ContentsContributors, vii Acronyms and Abbreviations, viii About the Companion Website, xiv PART 1 Examination Techniques, 1 1. Examination Techniques, 3 PART 2 Approach to Presenting Complaints, 11 2. Chest Pain, 13 3. Shortness of Breath, 28 4. Loss of Consciousness, 47 5. Palpitations, 62 6. Cardiac Murmurs, 72 7. Shock, 92 8. Oedema, 106 PART 3 Conditions, 117 9. Acute Coronary Syndrome, 119 10. Stable Angina, 138 11. Heart Failure, 147 12. Infective Endocarditis, 160 13. Arrhythmias, 172 14. Valvular Heart Disease, 193 15. Cardiomyopathy, 214 16. Hypertension, 232 17. Pericardial Disease, 245 18. Congenital Heart Disease, 261 PART 4 Imaging, 277 19. Electrocardiogram, 279 20. Transoesophageal Echocardiogram, 293 21. Trans-Thoracic Echocardiogram, 299 22. Cardiac MRI, 306 23. Cardiac CT, 313 24. Cardiac Catheterization, 320 PART 5 Interventional Therapies, 327 25. Pacemakers and Implantable Cardiac Defibrillators, 329 26. Percutaneous Coronary Intervention and Angioplasty, 338 27. Valvuloplasty, 348 28. Transcatheter Aortic Valve Implantation, 352 29. Cardiac Ablation, 359 PART 6 Pharmacology, 365 30. Anti-Arrhythmic Agents, 367 31. Beta-Blockers, 375 32. Calcium-Channel Blockers, 380 33. Nitrates, 385 34. Drugs Targeting the Angiotensin Axis, 389 35. Diuretics, 393 36. Anticoagulants, 399 37. Antiplatelets, 409 38. Lipid Regulation, 414 Index, 417

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Book SynopsisTable of ContentsContributors vii Preface xii About the Companion Website xiii Part I Introduction to Cardiac Ultrasound Imaging 1 Ultrasound Physics 3Jan D’hooge, Olivier Villemain, and Luc L. Mertens 2 Instrumentation, Patient Preparation, and Patient Safety 21Stacey Drant and Vivekanand Allada 3 Segmental Approach to Congenital Heart Disease 34Tal Geva 4 The Normal Pediatric Echocardiogram 47Wyman W. Lai and Jacqueline Wheatley Part II Quantitative Methods 5 Structural Measurements and Adjustments for Growth 69Steven D. Colan and Leo Lopez 6 Hemodynamic Measurements 87Mark K. Friedberg and Olivier Villemain 7 Left Ventricular Systolic Function Assessment 116Luc L. Mertens and Mark K. Friedberg 8 Diastolic Ventricular Function Assessment 146Peter C. Frommelt 9 Right Ventricular Function 168Luc L. Mertens and Andreea Dragulescu Part III Anomalies of the Systemic and Pulmonary Veins, Septa, and Atrioventricular Junction 10 Pulmonary Venous Anomalies 189David W. Brown 11 Systemic Venous Anomalies 213Jill J. Savla and Michael D. Quartermain 12 Anomalies of the Atrial Septum 228Tal Geva 13 Ventricular Septal Defects 247Shobha Natarajan and Meryl S. Cohen 14 Ebstein Anomaly, Tricuspid Valve Dysplasia, and Right Atrial Anomalies 267Frank Cetta and Benjamin W. Eidem 15 Mitral Valve and Left Atrial Anomalies 280James C. Nielsen and Daniela Y. Rafii 16 Common Atrioventricular Canal Defects 297Meryl S. Cohen Part IV Anomalies of the Ventriculoarterial Junction and Great Arteries 17 Anomalies of the Right Ventricular Outflow Tract and Pulmonary Valve 321Matthew S. Lemler, Poonam P. Thankavel, and Claudio Ramaciotti 18 Pulmonary Atresia with Intact Ventricular Septum 340Jami C. Levine 19 Abnormalities of the Ductus Arteriosus and Pulmonary Arteries 360Elizabeth Caris and Bhawna Arya 20 Anomalies of the Left Ventricular Outflow Tract and Aortic Valve 382John M. Simpson and Owen I. Miller 21 Hypoplastic Left Heart Syndrome 405Brian R. White, David J. Goldberg, and Jack Rychik 22 Aortic Arch Anomalies: Coarctation of the Aorta and Interrupted Aortic Arch 430Jan Marek, Matthew Fenton, and Sachin Khambadkone 23 Tetralogy of Fallot 463Shubhika Srivastava, Ira A. Parness, and Tal Geva 24 Truncus Arteriosus and Aortopulmonary Window 492Timothy C. Slesnick, Ritu Sachdeva, Joe R. Kreeger, Maria A. Pernetz, and William L. Border 25 Transposition of the Great Arteries 508Xavier Iriart, Meryl S. Cohen, and Luc L. Mertens 26 Double‐Outlet Ventricle 534Leo Lopez, Kuberan Pushparajah, and Tal Geva 27 Physiologically “Corrected” Transposition of the Great Arteries 560Erwin Oechslin and Andreea Dragulescu Part V Miscellaneous Cardiovascular Lesions 28 Hearts with Functional Single Ventricle, Superior‐Inferior Ventricles, and Crisscross Heart 585David N. Schidlow and Stephen P. Sanders 29 Echocardiographic Assessment of Functional Single Ventricles after the Fontan Operation 616Marc Gewillig and Luc L. Mertens 30 Cardiac Malposition and Heterotaxy Syndrome 635Lindsay S. Rogers and Meryl S. Cohen 31 Congenital Anomalies of the Coronary Arteries 658Shubhika Srivastava and Piers C. A. Barker 32 Vascular Rings and Slings 685Andrew J. Powell 33 Connective Tissue Disorders 700Julie De Backer and Shaine A. Morris 34 Cardiac Masses 728Michele A. Frommelt and Rebecca S. Beroukhim Part VI Anomalies of the Ventricular Myocardium 35 Dilated Cardiomyopathy, Myocarditis, and Heart Transplantation 747Renee Margossian 36 Hypertrophic Cardiomyopathy 772Colin J. McMahon and Javier Ganame 37 Restrictive Cardiomyopathy and Pericardial Diseases 794Dale A. Burkett and Adel K. Younoszai 38 Other Anomalies of the Ventricular Myocardium 822Rebecca S. Beroukhim and Steven D. Colan Part VII Acquired Pediatric Heart Disease 39 Kawasaki Disease 845Kevin G. Friedman 40 Acute Rheumatic Fever and Rheumatic Heart Disease 856Meghan Zimmerman and Craig Sable 41 Infective Endocarditis 870Manfred Otto Vogt and Andreas Kuhn Part VIII Special Techniques and Topics 42 Transesophageal and Intraoperative Echocardiography 885Owen I. Miller and John M. Simpson 43 Pregnancy and Heart Disease 904Anne Marie Valente 44 Fetal Echocardiography 924Lindsay R. Freud and Lisa K. Hornberger 45 Echocardiographic Assessment of the Transitional Circulation 964Amir H. Ashrafi, Gabriel Altit, and Patrick J. McNamara 46 Echocardiographic Assessment of Pulmonary Hypertension 992Pei‐Ni Jone 47 The Role of Multimodality Cardiovascular Imaging 1011Pierangelo Renella, Wyman W. Lai, and Ashwin Prakash Index 1031

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Book SynopsisThe definitive guide to the clinical and scientific aspects of pulmonary medicineâfully updated with the latest advances in the fieldA Doody's Core Title for 2024 & 2023!Fishmanâs Pulmonary Diseases and Disorders delivers unparalleled coverage of pulmonary medicine. With nearly 2500 illustrations, 60 videos, and 22,000 references, this peerless, two-volume resource provides a comprehensive overview of the scientific basis of lung function in health and disease.Youâll find detailed coverage of the broad array of disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms, respiratory infections, and respiratory failure. In addition, youâll learn about all the latest advances, including molecular development of the lung, stem cells and respiratory disease, the genetics of pulmonary disease, the growth of personalized medicine, technical adv

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Book SynopsisPart of the new Clinical Approach series—which focuses on key topics in cardiology—this pragmatic, comprehensive guide is intended for residents, practitioners, advanced practice nurses, and physician assistants, and covers arterial, venous, and lymphatic diseases. Easy-to-read chapters are written by clinical experts in interventional cardiology, interventional radiology, vascular surgery, and podiatry, and begin with helpful quick-reference summaries. Includes up-to-date information on imaging, complications, and limb salvaging, as well as pharmacology therapies such as drug-coated stents. Clinical algorithms help you make well-informed diagnostic, treatment, and disease management decisions. Guidance on the most current equipment and technology designed to ensure patients are treated with the most efficacious modalities available. Includes illustrations, photos, and other images. Enhance Your eBook Reading Experience<

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Book SynopsisThere has been an exponential increase in the amount of information available on the pathophysiology and management of heart diseases. Meanwhile, understanding of the underlying pathology and physiology has deepened and broadened with new methodologies to monitor cardiac structure and function. These developments have led to an overwhelming amount of information available to students, trainees, and physicians. What is in short supply is a comprehensive yet concise and clear description of the important cardiac conditions and disorders, an approach to their management, and an easily consulted and well-indexed summary to be used at the bedside or in the clinic. This book addresses that need.Trade Review"This is an excellent reference for practicing clinicians and trainees in the various fields of medicine that are involved in the care of patients with cardiovascular disease." - Joseph A Randy Englert III, MD(Ochsner Clinic Foundation), Doody's Book Review ServiceTable of ContentsCardiac diagnostic assessment. Coronary artery disease and myocardial infarction. Heart failure. Valvular heart disease. Diseases of the pericardium and myocardium. Arrhythmias. Adult congenital heart disease and heart disease in pregnant women. Peripheral vascular disease. Cardiovascular risk factors and other heart diseases.

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Book SynopsisAn in-depth review by leading authorities of the latest therapies and techniques for rescuing persons in cardiac arrest. The authors explore the physiology behind current state-of-the-art clinical resuscitation and translate it into practical bedside recommendations, clinical tips, and expert techniques. Topics of interest include the epidemiology of sudden death, management of ventilation, chest compression technique training, public access defibrillation, drug delivery during CPR, the latest drug therapies, and cardiac arrest in disease, pregnancy, drowning, lightning strike, and trauma. The authors also review the major ongoing research in resuscitation science that will likely affect the next set of international resuscitation guidelines.

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Book SynopsisExpert advice on how to live fearlessly with atrial fibrillation Renowned cardiac electrophysiologist Dr. Aseem Desai has made it his mission to significantly improve the lives of those diagnosed with AFib. Patients, their family, friends, and caregivers are often misinformed about the latest AFib research, advancements, and treatments. Many patients live in constant fear of their condition, and Dr. Desai believes that the resultant stress directly impacts their health. Dr. Desai diminishes the worry and confusion that comes with an AFib diagnosis by presenting the latest medical information in a concise and positive way, offering hope and encouragement to patients and their loved ones. Dr. Desai seeks to empower and inspire patients by providing straightforward answers and options to deal with this complex disease. Readers will: • Be Informed about what AFib is, why it happens, and what to do after a diagnosis • Be Prepared to deal with the diagnosis and condition on mental and emotional levels • Be in Control by learning to monitor the disease to prevent progression Restart Your Heart delivers cutting-edge information, options, and solutions-a complete AFib toolbox-that will afford readers a newfound sense of comfort, confidence, and control.

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Book SynopsisReaders discover the"new cardiology and its cellular secrets" in the rescue, restoration, and renewal of cardiac health.

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Book SynopsisResolving the Cholesterol Controversy recounts the science and scientific personalities behind the chain of discoveries upon which the lipid hypothesis of atherosclerosis was built.The narrative covers a period of just under 100 years, starting with Anitschkow's experiments with cholesterol-fed rabbits in 1913, and recounts the endeavours and achievements of the leading actors in this protracted scientific drama. The cast is drawn from an extraordinary variety of scientific disciplines: pathology, biophysics, epidemiology, nutrition, cardiology, lipidology, genetics, microbiology, pharmacology, and clinical trial design. Most of the scientists believed that cholesterol played a causal role in atherosclerosis and cardiovascular disease, but there were some who dissented strongly from this conclusion.The breadth of scientific disciplines involved in proving the lipid hypothesis is matched by the geographical spread of the participants. Anitschkow worked in Russia, Endo discovered the first statin in Japan, their commercial development by Merck took place in the USA and evidence of benefit from lowering cholesterol came from trials conducted in Scandinavia and the UK. The subsequent meta-analysis of these statin trials in 2005 proved the validity of the lipid hypothesis beyond any doubt. The history of how this all came about and its impact upon health policy and medical practice is recalled here in Resolving the Cholesterol Controversy.

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Book SynopsisA unique reference book covering the relevant basic sciences of cardiac anatomy, physiology and pharmacology through to the initial clinical assessment and investigation. It covers the core curricula for paediatricians in training at all levels including the MRCPCH and DCH examinations. This book is relevant to paediatricians in training, general practitioners, emergency department staff and specialist nurses. General staff working in specialist regional cardiac centres and healthcare professionals involved in the care of children and young people will also find this essential resource extremely useful. 'The aim of this handbook is to provide a rapid and reliable reference to congenital and acquired cardiac problems. It is very well organised. provides a more detailed discussion of cardiac physiology and pathophysiology and a comprehensive guide to ECG interpretation. It should be of particular interest to paediatricians in training, including those studying for higher professional examinations, but it also provides a valuable source of reference for paediatricians already in practice.' From the Foreword by Dr Christopher WrenTable of ContentsForeword. Acknowledgements. Introduction. Royal College of Paediatrics and child health examination structure. Basic cardiac anatomy, physiology and pharmacology. Examination of the cardiovascular system. Interpretation of the paediatric ECG. Investigations for suspected cardiac disease. A-z of cardiac disorders and procedures. Hot topics: a quick reference guide. 10 common cardiac disorders. 10 common presenting complaints. Appendix (reference tables and normal values). Glossary. Index.

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Book SynopsisTitles in the Pocket Tutor series give practical guidance on subjects that medical students and foundation doctors need help with ‘on the go’, at a highly-affordable price that puts them within reach of those rotating through modular courses or working on attachment. Topics reflect information needs stemming from today’s integrated undergraduate and foundation courses: Common presentations Investigation options (e.g. ECG, imaging) Clinical and patient-orientated skills (e.g. examinations, history-taking) The highly-structured, bite-size content helps novices combat the ‘fear factor’ associated with day-to-day clinical training, and provides a detailed resource that students and junior doctors can carry in their pocket. Key points New edition of the best-selling title that breaks down a complex and daunting subject using clearly-labelled, full-page ECG traces and concise but informative text Revised text and brand-new ECG traces bring the new edition fully up-to-date New chapters cover electrolyte and homeostatic disorders, and normal variants Logical, sequential content: relevant basic science, then a guide to understanding a normal ECG and the building blocks of an abnormal ECG, before describing clinical disorders Table of ContentsChapter 1 First principles 1.1 Anatomy 1.2 Physiology 1.3 Electrical activity and the ECG Chapter 2 Understanding the normal ECG 2.1 Introduction 2.2 The limb leads 2.3 The chest leads 2.4 The lead orientation 2.5 ECG nomenclature Chapter 3 Interpreting the ECG: a six-step approach 3.1 Step 1: is there electrical activity? 3.2  Step 2: what is the QRS (ventricular) rate? 3.3 Step 3: is the rhythm regular? 3.4 Step 4: is the QRS narrow (normal) or broad? 3.5 Step 5: is there atrial electrical activity? 3.6 Step 6: how is the atrial activity related to the ventricular activity? 3.7 Glossary of distinct ECG signs Chapter 4 Bradyarrhythmias I: sinoatrial node dysfunction 4.1 Sinus bradycardia 4.2 Sinus pause with junctional escape beat Chapter 5 Bradyarrhythmias II: conduction abnormalities 5.1 First-degree atrioventricular block 5.2 Second-degree atrioventricular block: Mobitz type 1 or Wenckebach 5.3 Second-degree atrioventricular block: Mobitz type 2 5.4 Second-degree heart block: 2:1 atrioventricular block 5.5 Third-degree (complete) atrioventricular block: narrow QRS 5.6 Third-degree (complete) atrioventricular block: broad QRS 5.7 Right bundle branch block 5.8 Left bundle branch block Chapter 6 Ectopic beats 6.1 Atrial ectopic beats 6.2 Ventricular ectopic beats 6.3 Junctional ectopic beats Chapter 7 Atrial arrhythmias 7.1 Atrial tachycardia 7.2 Multifocal atrial tachycardia 7.3 Atrial flutter 7.4 Atrial fibrillation 7.5 Atrial fibrillation with left bundle branch block Chapter 8 Narrow-complex tachyarrhythmias (supraventricular tachycardias) 8.1 Atrioventricular nodal re-entrant tachycardia 8.2 Atrioventricular reciprocating tachycardia 8.3 Wolff–Parkinson–White syndrome: right-sided pathway 8.4 Wolff–Parkinson–White syndrome: left lateral pathway 8.5 Wolff–Parkinson–White syndrome: posterior pathway 8.6 Wolff–Parkinson–White syndrome plus atrial fibrillation Chapter 9 Broad-complex tachyarrhythmias 9.1 Monomorphic ventricular tachycardia 9.2 Polymorphic ventricular tachycardia 9.3 Torsade de points 9.4 Ventricular fibrillation 9.5 Supraventricular tachycardia with bundle branch block Chapter 10 Ischaemia and infarction 10.1 ST segment depression (cardiac ischaemia) 10.2 Acute myocardial ischaemia: T wave inversion and the LAD syndrome 10.3 ST segment elevation myocardial infarction: anterior0 10.4 ST segment elevation myocardial infarction: acute inferior 10.5 ST segment elevation myocardial infarction: posterior 10.6 Completed myocardial infarction Chapter 11 Inherited arrhythmia problems 11.1 Hypertrophic cardiomyopathy 11.2 Arrhythmogenic right ventricular dysplasia 11.3 Long QT syndrome 11.4 Brugada syndrome Chapter 12 Cardiac chamber dilation, strain and hypertrophy 12.1 Left ventricular hypertrophy 12.2 Right ventricular hypertrophy 12.3 Pulmonary embolus 12.4 Left atrial dilation 12.5 Right atrial dilation Chapter 13 Electrolyte and homeostasis disorders 13.1 Hyperkalaemia 13.2 Hypokalaemia 13.3 Hypercalcaemia 13.4 Hypocalcaemia 13.5 Hypothermia Chapter 14 Miscellaneous conditions and normal variants 14.1 Pericarditis 14.2 Pacemaker 14.3 Biventricular pacemaker 14.4 Early repolarisation pattern 14.5 Non-pathological Q waves

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Book SynopsisThis new edition has been completely revised to take in all the NICE, ESC and ESVS guidelines that have been updated over the last 5 years. It continues to couple a comprehensive overview with an attractive design and student-friendly layout to produce a book that is accessible, relevant and current. Written by an experienced author team, it covers all the cardiology a medical student should know. Each section of the book starts with an ‘In a Heartbeat’ box which provides a useful summary of what you need to learn; these also act as excellent exam revision tools. The book is interspersed with a variety of additional features to help you understand the subject: Exam Essentials boxes tell you what you must know about the topic Pro-tips give you key extra knowledge to further improve your understanding New What’s the Evidence? boxes describe the key trials influencing practice Why? boxes explain the pathophysiology and rationale behind certain decisions and processes Guidelines summarise the recent recommendations from key bodies to ensure you are up to date with best practice. Cardiology in a Heartbeat will help you understand and appreciate the subject, succeed in your exams, and serve your patients to the best of your ability. Trade ReviewThe examiner's tips are really useful too! ‘Really clear, interesting and informative. This book outlines the key details that every medical student should know, but also explains some of the more detailed aspects of each topic. The examiner's tips are really useful too!' Amazon reviewer Great simple, easy-to-read and user-friendly layout ‘Great simple, easy-to-read and user-friendly layout. Love the "pro-tip" and "why" sections. Overall a great book for your cardiology rotation!' Amazon reviewer Easy to read ‘So glad i chose this book to buy, easy to understand, up to date and very nicely presented!' Amazon reviewer An excellent guide to cardiology ‘An excellent guide to cardiology. Full of concise up-to-date information , in a very practical and easy to read format. I would definitely recommend it to anyone undergoing a cardiology rotation.' Amazon reviewer Five Stars ‘It is a useful resource for a nursing student at an affordable price.' Amazon reviewer Very Good ‘Scion publishing has already satisfied me a lot with their Medical Rheumatology book. Due to the positive experience I decided to give their Cardiology book a try. As a matter of fact I did not get disappointed! Very good introduction to all interesting topics in cardiology including their treatment and clinical approach. A book full of useful mnemonics and clear definitions of specific cardiologic terminology...' Amazon reviewer Excellent Cardiology Guide ‘A fantastic and up to date cardiology guide for undergraduate medical students and foundation doctors. Explains everything in simple ways but also provides detailed information using guidelines etc. Particularly useful for Scotland or students studying at Edinburgh Medical School.' Amazon reviewer Easy to understand and informative ‘I bought this book as my mum had a heart attack and I wanted to understand how the heart worked, what was going on and what could be done. It was really informative and I found it easy to understand, it was perhaps an unusual book to be sat reading on a cardiac ward but it helped me understand what was going on. I would thoroughly recommend this for anyone wanting to learn more about the heart and cardiology.' Amazon reviewer Table of ContentsList of Contributors; Preface to the Second Edition; Foreword to the First Edition; Acknowledgements; List of Abbreviations; How to Use this Book 1. Anatomy and Physiology of the Cardiovascular System 2. History Taking and Physical Examination 3. Cardiovascular Medicine: an Investigative Approach 4. The Electrocardiogram 5. Cardiac Pharmacology 6. Infection and Pericardial Disease 7. Atherosclerosis 8. Ischaemic Heart Disease 9. Acute Coronary Syndrome 10. Heart Failure 11. Arrhythmias 12. Valvular Heart Disease 13. Hypertension 14. Cardiomyopathy 15. Peripheral Vascular Disease 16. Congenital Heart Disease 17. Cardiovascular Emergencies References; Appendix A Pharmacology Rapid Review; Appendix B Differential Diagnosis of Chest Pain; Appendix C Figure Acknowledgements; Index

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Book SynopsisCovering the range of pathologies that emergency medicine physicians, hospitalists, and internal medicine physicians see daily, A Visual Guide to ECG Interpretation, Third Edition, helps you easily recognize key ECG patterns, test your diagnostic skills, and quickly identify potentially lethal cardiac conditions. Drs. Susan R. Wilcox and David F. M. Brown use a combination of vivid illustrations, detailed annotations, clinical cases, and ECGs to help you recognize and interpret significant features. On the following page, abnormal patterns are enlarged, highlighted in color, and briefly described. The ECGs are presented with and without annotations to better test your diagnostic skills. Features hundreds of illustrations with detailed annotations, notes on underlying conditions, and discussions of abnormalities that help demystify ECG interpretation Depicts critical pathologies for quick recognition, including hyperkalemia, coronary occlusion, and

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Book SynopsisChapter 1: Introduction.- Chapter 2: Genesis of Cardiac Voltage Charges.- Chapter 3: Conceptualizing Electrocardiographic Forces.- Chapter 4: Specific Electrocardiographic Abnormalities.- Chapter 5: Common Arrhythmias.

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a huge range and FREE tracked UK delivery on ALL orders.

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Book SynopsisThis book elucidates a number of new concepts on P-wave evaluation and QRS depolarization properties, and reports on several repolarization findings never covered in previous ECG books. The content is primarily based on case reports, some of which are compared in order to reveal their ostensibly small but significant differences. The book addresses a significant and lingering gap in ECG interpretation, which is the actual cause of many poor decisions in the diagnostic and therapeutic contexts. Further, the book has an interdisciplinary appeal, and will be of equal interest to professionals and scholars with an interest in cardiology and ECG interpretation. Trade Review“This is a detailed guide to understanding important ECG cases and the appropriate approach to each ECG interpretation.The book has many useful figures and it provides many references at the end of each chapter.” (Mohanad Hasan, Doody's Book Reviews, April 26, 2019)Table of Contents1 The P wave and PR study: how they may help during sinus rhythm in defining pathology.- 2 Forseeing future arrhythmic events.- 3 Interpreting correctly some clinical findings ( syncope etc).- 4 Evaluation during Tachycardias : where to choose and how may be a diagnostic great help.- 5 The value of PR , blocked P waves in interpreting supra or subhisian site of blocks.- 6 QRS analysis in the diagnosis of aberrant conduction: new insights.- 7 QRS analysis during sinus rhythm for clinical practice purposes.- 8 Ecg interpretation of the supraventricular arrhythmias diagnosis.- 9 The repolarization patterns mimicking acute ischemia and uncorrectly leading to hospitalization, coronaroarteriography and faulse diagnosis of ischemic heart disease.- 10 Pitfalls and errors in the monitorings systems: how is the most correct interpretation.- 11 Some critical traces coming from normal pts 10) Some critical traces coming from non cardiological pts.- 12 Final considerations.

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Book SynopsisAn echocardiogram uses sound waves to produce images of the heart. This common test allows a doctor to see the heart beating and pumping blood, and subsequently identify heart disease. This book is a complete guide to performing and interpreting an echocardiogram. 56 chapters describe both basic and advanced techniques for diagnosing different heart disorders. The second edition has been fully revised to provide clinicians with the latest developments and techniques in the field. Seven new chapters have been added to this edition covering echocardiography and artificial intelligence, hypertension, arrhythmogenic right ventricular dysplasia, Kawasaki disease, cardio-oncology, diabetes mellitus, and foetal echo. Dedicated chapters emphasise the role of echo in surgical procedures, and explore its use with electrophysiology – in patients with pacemakers and those undergoing cardiac resynchronisation therapy. The book is highly illustrated with many 2D and 3D echo images helping explain the descriptive text for each topic. The previous edition (9789352700929) published in 2017.Table of Contents Basics of Ultrasound Introduction to Doppler Echocardiography How to do Basic Trans Thoracic Echocardiography Performance of Transesophageal Echocardiography: Basic Principles and Views Chamber Quantification: Left Ventricle Chamber Quantification: Right Ventricle Chamber Quantification: Left Atrium and Right Atrium Echocardiography in Pulmonary Hypertension Diastolic Function Echocardiographic Evaluation of Mitral Valve Echocardiographic Evaluation of Mitral Stenosis Step-by-Step Evaluation of Mitral Regurgitation using Echocardiography Examination of Valves: Aortic valve Echocardiography in Aortic Stenosis Echocardiography in Aortic Regurgitation Echocardiographic Evaluation of the Aorta Echocardiography for Cardiac Prevention Echocardiographic Assessment of Pulmonary Valve Echocardiographic Assessment of Tricuspid Valve Prosthetic Heart Valve: Echocardiographic Evaluation Pulmonary Thromboembolism Tissue Doppler and Strain Imaging: Physical Principles and Clinical Applications Three-dimensional/Four-dimensional Echocardiography Coronary Artery Disease Stress Echocardiography for the Evaluation of Coronary Artery Disease Myocardial Contrast Echocardiography Hypertrophic Cardiomyopathy Echocardiography in Dilated Cardiomyopathy Restrictive Cardiomyopathy Role of Echocardiography in Diagnosis of Acute Rheumatic Fever Pericardium and Pericardial Diseases: An Echocardiographic Study Pediatric Transthoracic Echocardiography: Basic Views Echocardiographic Assessment of Acyanotic Congenital Heart Diseases Congenital Cyanotic Heart Disease Echo in Emergency Room Cardiac Tumors Echocardiography in Infective Endocarditis Cardiovascular Manifestations of Systemic Diseases Artifacts in Echocardiography Interventional and Fusion Echocardiography Echocardiography for Transcatheter Aortic Valve Replacement Echocardiography in Percutaneous Mitral Valve Interventions Intravascular Ultrasound Echocardiographic Examination of a Patient with Pacemaker Echocardiography in Cardiac Resynchronization Therapy Left Atrial Appendage Echocardiography for Interventions in Congenital Heart Diseases: Left-to-right Shunt Lesions Echocardiography in Operation Theatre Echocardiographic Practices in India: Legal Issues Artificial Intelligence & Echocardiography: Current Status and Future Perspective Status of Echocardiography in Hypertension Arrhythmogenic Right Ventricular Cardiomyopathy Role of 2-D Echo in Evaluation of Coronary Artery Disease in Kawasaki Disease Echocardiography in Cardio Oncology Echocardiographic Evaluation of Diabetes Mellitus Fetal Echocardiography

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Book SynopsisTable of Contents1. Lessons Learnt from History of Rheumatic Heart Diseases 2. Rheumatic Fever and Rheumatic Heart Disease: A 4-century Review with Special Reference to India 3. Epidemiology of Group a Streptococcal Infections, Rheumatic Fever, and Rheumatic Heart Disease 4. Can We Change the Epidemiological Trend of Rheumatic Heart Disease in India? 5. Etiopathogenesis and Management of Streptococcal Infection 6. Laboratory Diagnosis of Group A B-hemolytic Streptococcal Infections 7. Etiopathogenesis and Pathology of Carditis in Rheumatic Fever 8. Pathology of Chronic Rheumatic Heart Disease 9. Etiopathogenesis, Clinical Manifestations, and Diagnosis of Acute Rheumatic Fever 10. Cardiac Complications of Acute Rheumatic Fever 11. Role of Echocardiography in Diagnosis of Carditis in Acute Rheumatic Fever 12. Clinical Profile of Rheumatic Heart Disease 13. Role of Echocardiography in Rheumatic Heart Disease 14. Consensus and Controversies in the Management of Acute Rheumatic Fever: Introducing Armor to Prevent and Protect 15. Medical Management of Rheumatic Heart Disease and Management during Pregnancy, Noncardiac Surgery, and Infective Endocarditis 16. Echocardiographic Screening for Rheumatic Heart Disease 17. Prevention and Vaccine for Rheumatic Fever: How Far are We? 18. Natural History of Rheumatic Fever and Rheumatic Heart Disease 19. Nonsurgical Management of Rheumatic Heart Disease 20. Transcatheter Treatment of Rheumatic Mitral Stenosis in Pediatric Age Group 21. Surgical Management of Rheumatic Heart Disease 22. Rheumatic Fever, Rheumatic Heart Disease Registry, and Control Program

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Book SynopsisTable of Contents1. What is an Echo? 2. Conventional Echo 3. Color Doppler Echo 4. Echo Windows 5. Normal Views and Values 6. Newer Modalities in Echo 7. Ventricular Dysfunction 8. Cardiomyopathies 9. Coronary Artery Disease 10. Systemic Hypertension 11. Pulmonary Hypertension 12. Diseases of Aorta 13. Congenital Diseases 14. Valvular Diseases 15. Pericardial Diseases 16. Endocardial Diseases 17. Intracardiac Masses 18. Thromboembolic Diseases 19. Systemic Diseases

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Book SynopsisAn ECG, or electrocardiogram, is a simple test that records the rhythm and electrical activity of the heart. It is commonly used to detect abnormal heart rhythms and investigate the cause of chest pains. It is important for clinicians to recognise and interpret ECG patterns accurately to ensure correct diagnosis and effective treatment. The sixth edition of ECG Made Easy has been fully revised to provide trainees and clinicians with the latest advances in the field. Beginning with an overview of ECG terms, leads and normal values, the following sections present numerous abnormal ECG readings and the resulting diagnoses. The book concludes with interesting cases diagnosed with ECG as well as instruction on how to effectively report ECG findings. This updated edition includes a new chapter covering the use of ECG in a patient fitted with a pacemaker. Each chapter features illustrative diagrams, graphs and tables. The book includes online access to supplementary videos detailing the basics of electrocardiography. Key Points Fully revised, new edition presenting latest advances in ECG Features new chapter on ECG with a pacemaker Includes online access to supplementary videos on ECG techniques Previous edition (9789386150219) published in 2016 Table of Contents Nomenclature of ECG Deflections Electrocardiographic Leads Electrocardiography Grid and Normal Values Determination of Electrical Axis Determination of Heart Rate Abnormalities of the P Wave Abnormalities of QRS Complex Abnormalities of the T Wave Abnormalities of the U Wave Abnormalities of PR Segment Abnormalities of ST Segment Abnormalities of PR Interval Abnormalities of QT Interval Premature Beats in Regular Rhythm Pauses during Regular Rhythm Fast Regular Rhythm with Narrow QRS Normal Regular Rhythm with Narrow QRS Fast Irregular Rhythm with Narrow QRS Fast Regular Rhythm with Wide QRS Normal Regular Rhythm with Wide QRS Fast Irregular Rhythm with Bizarre QRS Slow Regular Rhythm with Narrow QRS Slow Irregular Rhythm with Narrow QRS Slow Regular Rhythm with Wide QRS ECG in Patient on Pacemaker Interesting Cases Diagnosed by ECG How to Report an ECG ECG Findings in Specific Situations Index

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Book SynopsisEchocardiography provides all the information you need on acho acquisition, interpretation, and reporting. It has a companion website with over 150 videos to aid understanding, and also follows international accreditation guidelines.Trade ReviewReview from previous edition Highly Commended in the Cardiology Category * BMA Book Awards 2013 *Table of ContentsSection 1 1: Maryam Alsharqi: Ultrasound 2: Transthoracic examination 3: Kenneth Chan, Jonathan Choy, Jamie Kitt, Elizabeth Orchard, Rizwan Sarwar, Michael Stewart, James Willis, and Arash Yavari: Transthoracic anatomy and pathology: Chambers and vessels 4: Lucy Hudsmith, Saul Meyerson, William Moody, Jim Newton, David Oxborough, Bushra Rana, Liam Ring, and Benoy Shah: Transthoracic anatomy and pathology: Valves 5: Claire Colebourn: Acute and critical care echocardiography Section 2 6: Gosia Wamil: Transoesophageal examination 7: Michaela Scheuermann-Freestone and Michael Stewart: Transoesophageal: Chambers and Vessels 8: Lucy Hudsmith, Saul Meyerson, William Moody, Jim Newton, Elizabeth Orchard, Susanna Price, Bushra Rana, Liam Ring, Benoy Shah, and Arash Yavari: Transoesophageal: Valves 9: Contrast echocardiography 10: Andreas Helfen, Tyler Lamb, and Rizwan Sarwar: Stress echocardiography and coronary artery sonography 11: Jim Newton: Interventional echocardiography 12: Congenital heart disease 13: Quality assurance, reporting, and normal ranges

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Book SynopsisPacked with questions and answers to prepare for ABIM certification and maintenance of certification (MOC) exams in interventional cardiology, Interventional Cardiology Board Review: 1400+ Questions and Answers, Fourth Edition, is your go-to resource for exam success. Drs. Debabrata Mukherjee, Richard A. Lange, and Saurav Chatterjee use a real-world, multiple-choice format that closely follows the exam blueprint, along with hundreds of images, tables, and all-new videos that mimic what you’ll encounter on the exam. Detailed answers and explanations for each question provide an excellent resource for review as well as improve your ability to provide effective, evidence-based patient care. 1,400 multiple-choice questions directly align with ABIM certification and maintenance of certification (MOC) exams in interventional cardiology All of the questions for this fourth edition are new and reflect recent advancements, including the latest cathet

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Book SynopsisThis new volume on the heart and great vessels has been expanded to become a comprehensive atlas of all cardiovascular disease, both neoplastic and non-neoplastic. In the spirit of prior editions, correlation of expertly curated pathology photographs and photomicrographs with clinical presentation, imaging and molecular genetics remains the cornerstone. The spectrum of cardiovascular disease, both congenital and acquired, is vast; accounting for the relative size of this fascicle. Every attempt has been made to focus on the clinically-relevant features of the diseases helping not only pathologists, but also providing cardiologists, radiologists, and surgeons a reference to understand the pathologic basis of the conditions they diagnose and treat each day. The authors have meticulously provided gross photographs that mirror (where possible) planar imaging techniques that will enable pathologic-radiologic correlation and facilitate a multidisciplinary approach to patient care. Free digital access available with every print purchase. See inside the book for more details.

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Book SynopsisThe rollicking memoir from the cardiologist turned legendary scientist and winner of the Nobel Prize that revels in the joy of science and discovery. Like Richard Feynman in the field of physics, Dr. Robert Lefkowitz is also known for being a larger-than-life character: a not-immodest, often self-deprecating, always entertaining raconteur. Indeed, when he received the Nobel Prize, the press corps in Sweden covered him intensively, describing him as “the happiest Laureate.” In addition to his time as a physician, from being a "yellow beret" in the public health corps with Dr. Anthony Fauci to his time as a cardiologist, and his extraordinary transition to biochemistry, which would lead to his Nobel Prize win, Dr. Lefkowitz has ignited passion and curiosity as a fabled mentor and teacher. But it's all in a day's work, as Lefkowitz reveals in A Funny Thing Happened on the Way to Stockholm, which is filled to the brim with anecdotes and energy, and gives us a glimpse into the life of one of today's leading scientists. Trade Review"Cardiologist-turned-biochemist, Robert Lefkowitz won the 2012 Nobel Prize in Chemistry for showing how adrenaline works through stimulation of specific receptors, with huge implications for drug discovery. Yet he calls himself 'an accidental scientist,' because he trained as a physician. Instead of being drafted to the Vietnam War, he served at the US National Institutes of Health. His autobiography is a vividly anecdotal account, influenced by a supervisor’s lesson that data do not tell a story: 'A story is something you impose on the data.'" -- Andrew Robinson * NATURE *“Lefkowitz unveils the teamwork, persistence, and labors of love that go into living a life of significance. By turns funny and moving, this book has the power to inspire.” -- Mike Krzyzewski, Head Coach, Men’s Basketball, Duke University"This vivid tale shines with personality. Rarely has science been treated with such a winning blend of humor and humanity." * Publishers Weekly *"Lefkowitz is an avid and inveterate storyteller. Told with humor and humility, what shines through most is his love of stories. His passion for science and discovery, for helping people, and for celebrating stories is infectious." * Booklist *“An engaging Nobel Prize-winning journey of a life in medicine and science. Joyous, insightful, and irreverent, Lefkowitz describes the enormous impediments to challenging established dogma and legendary elders as well as the art and satisfaction of mentoring young scientists. For both lay readers and professional scientists, this book presents a narrative that will delight and that offers a goldmine of wisdom.” -- Robert Horvitz, Ph.D., Massachusetts Institute of Technology, Investigator of the Howard Hughes Medical Institute; Nobel Prize in Physiology or Medicine (2002)“Lefkowitz’s life is testament to the joy of science. The book is a page-turner, a riveting account of a life well-lived. It is a story of stories, a tale of greatness.” -- Roger D. Kornberg, Ph.D., Stanford University, Nobel Prize in Chemistry (2006)“In this engaging and often rollicking tale, Bob Lefkowitz recounts how the Vietnam War transformed him from a dedicated young physician into an enthusiastic, ambitious, and highly successful scientist whose discoveries have altered our understanding of cell function and approaches to drug development. Arriving at a time when the need to convert physicians into scientists is greater than ever, this book can do more than just entertain and instruct: it can inspire young doctors to remake their careers.” -- Harold Varmus, M.D., Lewis Thomas University Professor, Weill Cornell Medicine; Nobel Prize in Physiology or Medicine (1989); Author of The Art and Politics of Science“More than just a heartwarming and thrilling chronicle of a great physician-scientist, Lefkowitz has written a story-based leadership guide for any aspiring mentor. A testament to the power of building enduring excellence by believing in, championing, and developing others.” -- Sanyin Siang, Leadership Coach and author of The Launch Book“A spell-binding memoir, packed with deep insights and charged with the thrill of discovery. This is a tale told from the pinnacle of human achievement, that also serves as a master-class in humility and overcoming tragedy—all interwoven with laugh-out-loud anecdotes. Lefkowitz is a brilliant and charming storyteller, with an indomitable passion for living, and wisdom for the ages.” -- Karl Deisseroth, M.D., Ph.D., Stanford University, Winner of the Kyoto Prize and the Heineken Prize; Author of Projections“In this entertaining book, Nobelist Bob Lefkowitz recounts how he became a passionate and renowned physician-scientist. He unveils the secret to his scientific stardom in a series of engrossing stories spanning his fifty-year career. No tale is left untold—many are amusing, some might raise a few eyebrows.” -- Joseph L. Goldstein, M.D., and Michael S. Brown, M.D., U.T. Southwestern Medical Center, Nobel Prizes in Physiology or Medicine (1985)“Lefkowitz provides joyous remembrance of his amazing career as a physician-scientist. Interlaced with vignettes of personal sacrifice, growth, and friendship is the story of the seminal discoveries that culminated in science’s highest award. A beautiful story of family, hard work, and steadfast optimism.” -- Christine Seidman, M.D., Professor, Harvard Medical School, Director, CV Genetics Center Brigham and Women’s Hospital“How does a brilliant young physician accidentally get hooked on research? Bob Lefkowitz's life-altering shift changed not only his life but the lives of hundreds of his trainees. From the dazzling way adrenaline controls critical body functions to the thrill of his Nobel Prize win, this engaging book will help you better understand how physician scientists dedicate their careers to understanding human biology and enhancing human health." -- P. Roy Vagelos, M.D., Retired Chairman and CEO, Merck & Co.; Chairman of the Board, Regeneron Pharmaceuticals“Lighthearted, yet profoundly personal and moving, Lefkowitz’s memoir shares the secret recipe for winning a Nobel prize—two parts genius, one part audacity in challenging authority, one part insightful and supportive mentoring, a splash of good luck, and ten parts resilience and persistence. Bob Lefkowitz is at the top of the list of the extraordinary cadre of physicians turned scientists who ushered in the modern biotechnology revolution.” -- Barry S. Coller, M.D., David Rockefeller Professor of Medicine, Rockefeller University, Physician-in Chief, Rockefeller University Hospital"The odds of a scrappy kid growing up in the Bronx winning a Nobel Prize are overwhelmingly small. How Bob Lefkowitz managed to do this is revealed in this delightfully rich and moving book allowing the reader to understand Bob’s intelligence, warmth, and complexity. If you read one book this year, choose this one. It will fill you with joy, hope, and give you a new friend.” -- Ralph Snyderman, M.D., Professor of Medicine, Chancellor Emeritus, Duke University“A blend of comedy, history, and tragedy, this book is much more than a delightfully amusing tale of a bright kid from the Bronx who ultimately wins a Nobel Prize. Bob Lefkowitz’s message is of the utmost importance. U.S. taxpayer dollars funded a unique cadre of young physicians—'the Yellow Berets’—whose discoveries have led to revolutionary therapies for heart disease, cancer, diabetes, impotence, neurodegeneration, HIV, and coronavirus, all while training the next generation of medical scientists. Reading this book shows that investments in science will continue to save the world.” -- Peter Agre, M.D., Professor and Director, Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health; Nobel Prize in Chemistry (2003)“Robert Lefkowitz’s memoir is a rollicking, absorbing read. It turns out many funny things happened on his way to Stockholm. Beautifully written, this book demonstrates the importance of humor, humility, and humanity in the pursuit of scientific discovery." -- Jerry Speyer, Chairman, Tishman-Speyer"A deeply personal perspective of events, people, thoughts, and actions that have created an era of major scientific breakthroughs. Full of insights and revelations about the milieu that underlies today’s biomedical revolution, from a key participant. Written with a candor and style that make Bob Lefkowitz’s life adventures as a physician-scientist a delight to read.” -- Stanley N. Cohen, M.D., Professor of Genetics and Medicine, Stanford University“Bob Lefkowitz is a legend in his own time. In addition to his clinical background as an MD and acknowledged scientific mettle resulting in a Nobel Prize, he is a renowned raconteur. Bob also has an excellent sense of humor, and these twin skills have made him a highly sought-after public speaker. They are both on vivid display in this highly readable and entertaining autobiography, which begins with his childhood in the Bronx and embraces his long and distinguished career.” -- Michael Rosbash, Ph.D., Peter Gruber Professor of Neuroscience, Brandeis University, Investigator of the Howard Hughes Medical Institute“Lefkowitz is not only a gifted scientist, but also a gifted story-teller. From the Yankees to Duke basketball to the game show Jeopardy through the upper echelons of science on his way to a Nobel Prize, he proves that science can be fun and rewarding for himself, the field, and his patients." -- Brian Druker, M.D., Director, Knight Cancer Institute, Oregon Health & Science University“Lefkowitz appreciates the power of storytelling, both at the bedside in making diagnoses and at the bench in generating hypotheses. Full of vignettes that are sometimes embarrassingly honest, at other times laugh-out-loud humorous, but always infused with his own special brew of humility and hubris. An informative and entertaining read.” -- Helen H. Hobbs, Investigator, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center“A tribute to teamwork that aims to inspire the young generation of scientists to take a similar journey. This book shows that making a breakthrough discovery, changing a paradigm, and using science as a tool to change people’s lives is possible, while also emphasizing that such achievements are not made by angels but by human beings like all of us.” -- Aaron Ciechanover, M.D., D.Sc., Technion, Israel Institute of Technology, Nobel Prize in Chemistry (2004)

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Book SynopsisThis textbook provides in depth learning for nurses specialising in caring for patients with coronary heart disease, heart failure, valvular disease, arrhythmias, congenital heart disease and inherited cardiovascular conditions.Table of ContentsSection 1 - The Centrality of Nursing within Cardiovascular Care 1: Guy De Backer, Ian Graham, María Teresa Lira, Laura Hayman, and Izabella Uchmanowicz: The epidemiology of cardiovascular disease 2: Maria Teresa Lira, Ercole Vellone, Donna Fitzsimons, Lisa Dullagan, and Julie Sanders: Delivering high quality cardiovascular care 3: Lis Neubeck, Jenni Jones, Izabella Uchmanowicz, Sue Koob, Catriona Jennings, Maria Teresa Lira, Shirley Ingram, and Donna Fitzsimons: Key considerations for continuing professional development and specialisation 4: Geraldine Lee, Gabrielle McKee, Andrea Protopapas, and Ian D Jones: Anatomy and Physiology of the Healthy Heart Section 2 - Holistic Nursing Care: Assessment, Intervention and Evaluation 5: Diane L. Carroll, Howard T Blanchard, Eleni Kletsiou, Felicity Astin, Alison Woolley, Jo Tillman, Ricardo Leal, Rosie Cervera-Jackson, and Ekaterini Lambrinou: Nursing assessment and care planning in the context of cardiovascular care 6: Valentino Oriolo, Margaret Cupples, Neil Angus, Susan Connolly, and Felicity Astin: Care of the patient with Coronary Heart Disease 7: Gerry Lee, Nina Fålun, Neil Angus, Jeroen Hendriks, Tone Norekval, and Donna Fitzsimons: Care of the patient with cardiac arrhythmias 8: Tone M Norekvål, Britt Borregaard, Tina B Hansen, Trine B Rasmussen, and Sandra B Lauck: Care of the patient with valvular heart disease 9: Jodie Ingles, Tootie Bueser, Pascal McKeown, Philip Moons, and Donna Fitzsimons: Care of the patient with inherited cardiac conditions and congenital diseases 10: Tiny Jaarsma, Anna Stromberg, Ekaterini Lambrinou, Andreas Protopapas, Loreena Hill, Ana Ljubas and David R Thompson: Care of the patient with heart failure 11: Catriona Jennings, Kathy Berra, Laura Hayman, Irene Gibson, Jennifer Jones, Alison Atrey, David R Thompson, Chantal F Ski, Mary Kerins, Tara Conboy, Lis Neubeck, Robyn Gallagher, and Sue Koob: Cardiovascular prevention and rehabilitation 12: Jan Keenan, Rani Khatib, Gabrielle McKee, Todd Ruppar and Franki Wilson: Pharmacology for Cardiovascular Nurses Section 3 - Professional Considerations for Nurses Working in Cardiovascular Care 13: Felicity Astin, Emma Harris, Lis Neubeck, Robyn Gallagher, and Jennifer Jones: Patient Education and communication 14: David R Thompson, Izabella Uchmanowicz, Jan Keenan, Rani Khatib, Loreena Hill, Ekaterini Lambrinou, Martha Kyriakou, and Lis Neubeck: Addressing the current challenges for the delivery of holistic care 15: David R Thompson, Lis Neubeck, and Robyn Gallagher: Looking forward: the future of cardiovascular care

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Book SynopsisTable of Contents1. Foreword2. Introduction and Implications for Effective Cholesterol Lowering3. Complementary Mechanisms for CVD4. Reducing Cholesterol and overall CVD risk5. Soy and lowered CVD risk6. Nuts and lowered CVD risk7. Plant Sterols and lowered CVD risk8. Viscous Fibers and lowered CVD risk9. Practical Advice10. Tips, Menus, and Recipes

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Book SynopsisCardiac catheterization and coronary angiography are both key components to routine cardiology practice. This new edition of Cardiac Catheterization and Coronary Intervention has been fully updated since the first edition, with new sections on primary percutaneous coronary intervention, trends in vascular access, bioabsorbable stents, optical coherence tomography, and more. Filled with over 150 clinical images and schematic illustrations, the handbook is an accessible ''how-to'' guide, designed to de-mystify complex cardiac catheterization investigations. Expanded to reflect developments in practice, this new edition also introduces a new chapter on the multidisciplinary team and their roles and responsibilities from pre- to post-procedural care and relevant training requirements.Containing detailed instructions on how to perform a comprehensive left and right heart catheterization procedure, choosing the correct catheter for coronary and graft angiography, and how to perform a diagnosTable of Contents1: Introduction 2: The team 3: Vascular access 4: Cardiac catheterization 5: Specific conditions 6: Coronary angiography 7: Coronary artery bypass graft angiography 8: Percutaneous coronary intervention 9: Additional procedures 10: Complications 11: Post procedure

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Book SynopsisTrade Review"This book is easy to read, and a treat for clinicians who look forward to treating patients with heart rhythm disorders. It is an ideal handbook, appropriately comprehensive while easy to read. It covers the basics of arrhythmia recognition as well as providing algorithms on the management of simple and complex arrhythmias. While the audience for the book is narrow, that is by intention, as it focuses on a very specific aspect of cardiology. It is an essential title for cardiologists and cardiology fellows who must diagnose and treat heart rhythm disorders daily." Reviewed by Mohammed A. Ahmed, DO (Ochsner Clinic Foundation)Table of ContentsChapter 1. Sinus Node - Normal and Abnormal Rhythms Chapter 2. Bradyarrhythmias - Conduction System Abnormalities Chapter 3. Ectopic Complexes and Rhythms Chapter 4. Tachycardia Chapter 5. Supraventricular Tachyarrhythmias Chapter 6. Ventricular Tachyarrhythmias Chapter 7. Cardiac Pacing and Pacemaker Rhythms Chapter 8. Implantable Cardioverter Defibrillators Chapter 9. Drug Effects and Electrolyte Disorders Chapter 10. Athletes and Arrhythmias Chapter 11. Evaluation of the Patient with Suspected Arrhythmias Chapter 12. Treatment of Arrhythmias Chapter 13. Management of Arrhythmias in Pregnancy

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Book SynopsisTrade Review"This book remains the flagship in this discipline from Elsevier. The quality of illustrations and overall organization have been retained from the second edition." -David J. Dries, MD (University of Minnesota Medical School) Doody's Score: 93-4 Stars!Table of ContentsSection I. Introduction 1. Evolution of the Coronary Care Unit: Past, Present, and Future 2. Ethical Issues of Care 3. Physical Examination Section II. Scientific Foundation of Cardiac Intensive Care 4. The Role of the Cardiovascular System in Coupling the External Environment to Cellular Respiration 5. Regulation of Cardiac Output 6. Coronary Physiology and Pathophysiology 7. Pathophysiology of Acute Coronary Syndromes: Plaque Rupture and Atherothrombosis 8. Regulation of Hemostasis and Thrombosis Section III. Coronary Artery Disease Acute Myocardial Infarction 9. Diagnosis of Acute Myocardial Infarction 10. Use of the Electrocardiogram in Acute Myocardial Infarction 11. Reperfusion Therapies for Acute ST- Elevation Myocardial Infarction 12. Adjunctive Pharmacologic Therapies in Acute Myocardial Infarction Complications of Acute Myocardial Infarction 13. Post-Myocardial Infarction Cardiogenic Shock 14. Right Ventricular Infarction 15. Mechanical Complications of Acute Myocardial Infarction 16. Supraventricular and Ventricular Arrhythmias in Acute Myocardial Infarction 17. Conduction Disturbances in Acute Myocardial Infarction Complications of Percutaneous Interventional Procedures Section IV. Noncoronary Diseases: Diagnosis and Management 18. Acute Heart Failure and Pulmonary Edema 19. Acute Fulminant Myocarditis 20. Stress (Takotsubo) Cardiomyopathy 21. Distributive Shock 22. Cardiorenal Syndrome 23. Sudden Cardiac Death 24. Diagnosis and Treatment of Ventricular Tachycardia 25. Diagnosis and Treatment of Unstable Supraventricular Tachycardia 26. Acute Presentations of Valvular Heart Disease 27. Hypertensive Emergencies 28. Acute Aortic Syndromes: Diagnosis and Management 29. Acute Pericardial Disease 30. Acute Respiratory Failure 31. Massive Acute Pulmonary Embolism 32. Pulmonary Hypertension 33. Hemodynamically Unstable Presentations of Congenital Heart Disease in Adults 34. Overdose of Cardiotoxic Drugs Section V. Pharmacologic Agents in the Cardiac Intensive Care Unit 35. Anticoagulation: Antithrombin Therapy 36. Anti-platelet Therapy 37. Inotropic and Vasoactive Agents 38. Intensive Diuresis and Ultrafiltration 39. Antiarrhythmic Electrophysiology and Pharmacotherapy 40. Analgesics, Tranquilizers, and Sedatives 41. Pharmacologic Interactions Section VI. Advanced Diagnostic and Therapeutic Techniques: Indications and Technical Considerations 42. Central Venous Access Procedures 43. Temporary Pacing 44. Pericardiocentesis 45. Invasive Hemodynamic Monitoring 46. Temporary Mechanical Circulatory Support Devices 47. Ventricular Assist Device Therapy in Advanced Heart Failure 48. Heart Transplantation for Advanced Heart Failure 49. Emergency Airway Management 50. Mechanical Ventilation 51. Cardiopulmonary Cerebral Resuscitation after Cardiac Arrest 52. Palliative Care

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Book SynopsisTable of Contents1. Anatomy and Physiology of the Heart 2. ECG Leads and Cardiac Monitoring 3. Components of the ECG Waveform 4. Step-by-Step ECG Interpretation 5. Sinus Rhythms 6. Atrial Rhythms 7. Junctional Rhythms 8. Ventricular Rhythms 9. Atrioventricular Blocks 10. Implanted Pacemaker Rhythms 11. Treatment of Rhythm Disturbances 12. The 12-Lead ECG: Leads and Axis 13. Bundle Branch and Fascicular Blocks 14. Hypertrophy, Electrolytes, and Other ECG Findings 15. Coronary Heart Disease and the 12-Lead ECG 16. ECG Diagnosis of Myocardial Infarction 17. Diagnosis and Treatment of Acute Coronary Syndromes Appendix A: Methods of Determining the QRS Axis Appendix B: Answers to Chapter Review Questions Appendix C: Rhythm Interpretation Self-Assessment Appendix D: Self-Assessment Answer Key Glossary

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Book SynopsisTrade Review"This book is a comprehensive study guide with multiple choice questions designed to accompany Braunwald's Heart Disease, 12th Edition, Libby et al. (Elsevier, 2022). The previous edition of this book was published in 2019." ©Doody's Review Service, 2023, Sathvika Reddy Gaddam, MD (East Tennessee State University Quillen College of Medicine)Table of ContentsSection 1: Fundamentals of Cardiovascular Disease; Genetics and Personalized Medicine; Evaluation of the Patient Section 2: Heart Failure; Arrhythmias, Sudden Death, and Syncope Section 3: Preventive Cardiology; Atherosclerotic Cardiovascular Disease Section 4: Diseases of Heart Valves, Myocardium, Pericardium, and Pulmonary Vascular Bed Section 5: Cardiovascular Disease in Special Populations; Cardiovascular Disease and Disorders of Other Organs

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Book SynopsisTrade Review"The authors have met their objective in providing the most current, high-quality content in an intelligible fashion. Overall, this book will be a valuable resource for its intended audience, as well as any medical professionals interested in CIEDs." ©Doody's Review Service, 2022, Madyson P Middleton, BS, MD Candidate (Middle Tennessee State University)Table of ContentsPacemakers Implantable Cardioverter-Defibrillators Cardiac Resynchronization Therapy Devices CIED Complications Novel CIEDs (S-ICD and leadless pacemaker) Implantable Cardiac Monitors

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Book SynopsisTable of ContentsPrehospitalization Symptom Perceptions, Lay Consultations, and Treatment-Seeking for Acute Decompensating Heart Failure: Implications for Nursing PracticeThe Perfect Storm: Barriers to Heart Failure Treatment OptimizationRole of Telemedicine in Improving Guideline-Directed Medical Treatment for Patients with Heart Failure During a PandemicDepression and Heart Failure Assessment, Treatment, and Interventions to Improve Self-Care BehaviorsTreating Sepsis in Patients with Heart FailureEducating Bachelor of Science in Nursing Students in Leadership Strategies Needed for Care Management and Disease Management for the Heart Failure Patient PopulationPrevention of Pressure Injury in Patients Hospitalized with Heart FailureImplementing Evidence-Based Motivational Interviewing Strategies in the Care of Patients with Heart FailureTranscatheter Aortic Valve Replacement Patient Care Improvements; It Takes a TeamSetting a Benchmark for Quality of Care: Update on Best Practices in Transcatheter Aortic Valve Replacement ProgramsTransition to Practice: Implementing Healthy Work Environment Standards through Nurse Resident-Led Evidence-based Practice Change in Transcatheter Aortic Valve Replacement Care on a Cardiac Telemetry Unit

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Book Synopsis

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