Biotechnology Books
CRC Press Biomolecular Crystallography Principles Practice
Book SynopsisSynthesizing over thirty years of advances into a comprehensive textbook, Biomolecular Crystallography describes the fundamentals, practices, and applications of protein crystallography. Deftly illustrated in full-color by the author, the text describes mathematical and physical concepts in accessible and accurate language. It distills key concepts for understanding the practice and analysis of protein crystal structures and contains examples of biologically-relevant molecules, complexes, and drug target structures.Biomolecular Crystallography will be a valuable resource for advanced undergraduate and graduate students and practitioners in structural biology, crystallography, and structural bioinformatics.Trade Review"Over the past 34 years Louise and I have often discussed the possibility of updating [Protein Crystallography]....However, this marvelous text by Bernhard Rupp provides everything that we could have done and more: indeed all that is required for the student of 2010. Biomolecular Crystallography is an impressive volume. Its 808 pages are beautifully written and wonderfully illustrated, many in colour....This book will be an essential part of the library of any department that claims to make contributions to modern biology....[and] a necessary addition also to the libraries of big pharmaceutical companies and small biotechs. This is a book to be enjoyed by all who wish to become structural biologists. I am also sure that many practicing structural biologists - even some who consider themselves mature - would do well to read its pages." - Tom Blundell, Journal of Applied Crystallography"It is a masterpiece. It is the book which the MX community has been waiting for and it is an absolute must-have for everybody in the field." - Acta CrystallographicaPRAISE FOR Biomolecular Crystallography:"Over the past 34 years Louise and I have often discussed the possibility of updating [Protein Crystallography]....However, this marvelous text by Bernhard Rupp provides everything that we could have done and more: indeed all that is required for the student of 2010. Biomolecular Crystallography is an impressive volume. Its 808 pages are beautifully written and wonderfully illustrated, many in colour....This book will be an essential part of the library of any department that claims to make contributions to modern biology....[and] a necessary addition also to the libraries of big pharmaceutical companies and small biotechs. This is a book to be enjoyed by all who wish to become structural biologists. I am also sure that many practicing structural biologists - even some who consider themselves mature - would do well to read its pages." - Tom Blundell, Journal of Applied Crystallography"It is a masterpiece. It is the book which the MX community has been waiting for and it is an absolute must-have for everybody in the field." - Acta Crystallographica"This is the book that molecular biologists and the crystallographic community have been waiting for." - Alexander McPherson, University of California at Irvine, USA'Biomolecular Crystallography is first and foremost a comprehensive reference text and laboratory manual for the practicing structural biologist, from the basics of biomolecular structure to modern advanced and powerful techniques in biomolecular structure determination, and analysis and application of structural information. Figures and graphs computed from new and original data are used extensively to help clarify important concepts, and derivations of all relevant mathematical and statistical principles—many of which have never been brought together in a single volume—are presented. This fulfils a long-felt need!' - Ian J. Tickle, Astex Therapeutics, Cambridge, UK'This thorough treatment of modern macromolecular X-ray crystallography combines a comprehensive coverage of the fundamentals with methodological details that are often omitted in introductory texts. It will be of value to anyone that works in macromolecular X-ray crystallography, particularly to graduate students or postdoctoral fellows who are mastering the technique.' - Mark Wilson, University of Nebraska, USA'Given the extraordinary progress in biomolecular crystallography, the challenge of providing a comprehensive and authoritative overview, starting from first principles, is formidable. Dr Rupp has, however, succeeded admirably.' - Brian Matthews, University of Oregon, USATable of ContentsPART I: FROM SEQUENCE TO CRYSTALS 1. Introduction: Preparing Your Study 2. Protein Structure 3. Protein Crystallization 4. Proteins for Crystallography PART II: FUNDAMENTALS OF PROTEIN CRYSTALLOGRAPHY 5. Crystal Geometry 6. Diffraction Basics 7. Statistics and Probability in Crystallography PART III: FROM CRYSTALS TO DATA 8. Instrumentation and Data Collection PART IV: DETERMINING YOUR STRUCTURE 9. Reconstruction of Electron Density and the Phase Problem 10. Experimental Phasing 11. Non-Crystallographic Symmetry and Molecular Replacement 12. Model Building and Refinement PART V: MAKING SENSE OF YOUR STRUCTURE 13. Structure Validation, Analysis, and Presentation
£131.34
Taylor & Francis Ltd Ethics for Bioengineering Scientists
Book SynopsisThis book introduces bioengineers and students who must generate and/or report scientific data to the ethical challenges they will face in preserving the integrity of their data. It provides the perspective of reaching ethical decisions via pathways that treat data as clients, to whom bioengineering scientists owe a responsibility that is an existential component of their professional identity. The initial chapters lay a historical, biological and philosophical foundation for ethics as a human activity, and data as a foundation of science. The middle chapters explore ethical challenges in lay, engineering, medical and bioengineering scientist settings. These chapters focus on micro-ethics, individual behavior, and cases that showcase the consequences of violating data integrity. Macro-ethics, policy, is dealt with in the Enrichment sections at the end of the chapters, with essay problems and subjects for debates (in a classroom setting). The book can be used for individual study, usTable of Contents1. Bioengineering and ethics: Objective data vs. subjective reason. 2. Does ethical behavior have a biological foundation? 3. Moral analysis: Philosophical foundations of ethical action. 4. Moral analysis: Deriving a moral decision. 5. Separating professional from lay ethics. 6. Engineering ethics. 7. Medical ethics. 8. Bioengineering scientist ethics. 9. Ethics of research with non-human animals. 10. Health professionals and historic human research ethics. 11. Health professionals and modern human research ethics. 12. Medical product development and the FDA. 13. Ethics of medical product failure and the courts. Appendix A: Suggested Debate format. Appendix B: Informed Consent. Appendix C: Advanced Care Directive. Appendix D: UCLA Policy 993. Appendix E: Significant events in the history of human experimentation. Appendix F: Examples for Safe Medical Devices Act report incidents.
£175.00
CRC Press Biofuels
Book SynopsisOffering a comprehensive overview of biofuels and bioenergy systems, Biofuels: Technologies, Policies, and Opportunities describes advances in technologies and global policies around biofuels as a renewable energy source. It discusses the basics of biofuel and bioenergy systems and current status and potential challenges in developed and developing countries. The book also highlights the questions that should be asked, available options, and processes (conventional and advanced) to enhance biofuel production. Details how technological interventions can influence the operation of an effective bioenergy system. Presents information regarding renewable energy directives and global policies related to energy chains, energy models, market status, and appropriateness of technology selection for different generations of biofuel generation. Covers socio-economic aspects and techno-economic feasibility as well as a detailed life cycle simulations (LCS) approach, revealing the real constraints being faced in the biofuels sector. Helps bioenergy professionals to prepare a roadmap for day-to-day operations. Describes recent advances such as biohythane, advanced oxidation process, and nanocatalyzed pretreatment for biofuel generation from wastewater. Addresses the most commonly discussed issues in the biofuel sector and the rationales underpinning them. Written for professionals, academic researchers, decision makers, and policymakers in the biofuel sector, this book provides readers with a wide-ranging review of current research and developments in the respective field.
£50.34
Taylor & Francis Ltd MultiPronged Omics Technologies to Understand
Book SynopsisCOVID-19 and Omics Technologies is a comprehensive, integrative assessment of recent information and knowledge collected on SARS-CoV-2 and COVID-19 during the pandemic based on omics technologies. It demonstrates how omics technologies could better investigate the infectious disease and propose solutions to the current concerns.The value of multi-omics technologies in understanding disease etiology and host response, discovering infection biomarkers and illness prediction, identifying vaccine candidates, discovering therapeutic targets, and tracing pathogen evolution is discussed in this book. These factors combine to make it a valuable resource to enhance understanding of both Omics technology and COVID-19 as a disease. The book covers the most recent understanding of COVID-19 and the applications of cutting-edge studies, making it accessible to a large multidisciplinary readership.The book explains how high-throughput technologies and systems biology might assist toTable of ContentsClinical and Epidemiological Context Of COVID-19. NGS technologies for detection of SARS-CoV-2 strains and mutations. Mass-spectrometry techniques for detection of COVID-19 viral and host proteins using naso-oropharyngeal swab and plasma. Targeted proteomic approaches in context of the COVID-19 pandemic. Metabolomics: Role in pathobiology and therapeutics of COVID-19. Protein microarrays for COVID-19 research: biomarker discovery, humoral response & vaccine targets. COVID-19 pathogenesis and host immune response. Putative role of multi-omics technologies in the investigation of the persistent effects of COVID-19 on vital human organs. Insights on interactomics driven drug repurposing to combat COVID-19. Spectroscopy methods for SARS-CoV-2 detection. Role of AI and ML in empowering and solving problems linked to COVID-19 pandemic.
£118.75
CRC Press Biofungicides EcoSafety and Future Trends
Book SynopsisThe current volume focuses on all the major concerns associated with the biofungicides and provides comprehensive knowledge of microbial and phytochemical fungicides, bioformulations, regulation as well as limitation of biofungicides, and their role in disease management in plants. The use of biofungicides as eco-friendly alternative to traditional synthetic fungicides is likely to play a major role in organic farming in the future.
£63.64
CRC Press Laboratory Manual for Biotechnology and
Book SynopsisProvides the basic laboratory skills and knowledge to pursue a career in biotechnology. Written by four biotechnology instructors with over 20 years of teaching experience, it incorporates instruction, exercises, and laboratory activities that the authors have been using and perfecting for years. These exercises and activities help students understand the fundamentals of working in a biotechnology laboratory. Building skills through an organized and systematic presentation of materials, procedures, and tasks, the manual explores overarching themes that relate to all biotechnology workplaces including forensic, clinical, quality control, environmental, and other testing laboratories.Features:â Provides clear instructions and step-by-step exercises to make learning the material easier for students. There are Lab Notes for Instructors in the Support Material (see tab below).â Emphasizes fundamental laboratory skills that prepare students for thTrade ReviewThis hefty, 1,171-page, paperback book is worth its weight in gold. What a fantastic reference for the various aspects of biotechnology. I loved the emphasis on the "relationship between proper fundamental practices and reproducibility," and the authors' steadfast commitment to providing a "solid grounding in basic, quality practices" essential for success in biotechnology.The sheer size and comprehensiveness of this book reinforces their introductory statement, "..'biotechnology' is not a synonym for 'molecular biology.'" Pretty much every possible test method used in a biotechnology setting (e.g., cell culture, chromatography, immunoassay) and their essential quality components (e.g., measurements such as weight and temperature; and solutions - love the declarative statement for section 24.1.1.2: "water is not pure") are described in great detail. Case studies accompany each chapter for the learners to test their retention and understanding. A nice inclusion is the section on regulatory affairs for learners to appreciate the challenges of bringing a biotechnology product to the consumer. This is a fabulous textbook. If you work in biotechnology, this should be on every workbench and administrative office (e.g., supervisors, regulatory, quality assurance) for easy reference and, most importantly, adherence toquality practices.Valerie L Ng, PhD MD(Alameda County Medical Center/Highland Hospital)Table of ContentsUNIT I SAFETY IN THE LABORATORYUnit Introduction SAFETY PART 1: CREATING A SAFE WORKPLACE Fundamental Principles Classroom Activity 1: Performing a Risk Assessment Classroom Activity 2: Exploring Safety-Related Government Web Sites Classroom Activity 3: Responding to Emergencies SAFETY PART 2: WORKING SAFELY WITH CHEMICALSFundamental Principles Classroom Activity 4: Understanding the Chemicals with Which You Work Classroom Activity 5: Personal Protection Laboratory Exercise 1: Tracking the Spread of Chemical Contamination Classroom Activity 6: Analyzing Safety Issues in a Laboratory Procedure SAFETY PART 3: WORKING SAFELY WITH BIOLOGICAL HAZARDSFundamental Principles Laboratory Exercise 2: Production of Bioaerosols and Factors Affecting Aerosol Production Unit Discussion Safety Contract, student copy Safety Contract, to turn in UNIT II DOCUMENTATION IN THE LABORATORY Unit Introduction Classroom Activity 7: Being an Auditor Laboratory Exercise 3: Keeping a Laboratory Notebook Classroom Activity 8: Writing and Following an SOP Unit Discussion UNIT III METROLOGY IN THE LABORATORY Unit Introduction Laboratory Exercise 4: Recording Measurements with the Correct Number of Significant Figures Classroom Activity 9: Constructing a Simple Balance Laboratory Exercise 5: Weight Measurements 1: Good Weighing Practices Laboratory Exercise 6: Weight Measurements 2: Performance Verification Laboratory Exercise 7: Volume Measurements 1: Proper Use of Volume Measuring Devices Laboratory Exercise 8: Volume Measurements 2: Performance Verification of a M Micropipette Laboratory Exercise 9: Measuring pH with Accuracy and Precision Unit Discussion UNIT IV SPECTROPHOTOMETRY AND THE MEASUREMENT OF LIGHT Unit Introduction Laboratory Exercise 10: Color and the Absorbance of Light Laboratory Exercise 11: Concentration, Absorbance, and Transmittance Laboratory Exercise 12: Preparing a Standard Curve With Food Coloring and Using it for Quantitation Classroom Activity 10: Beer’s Law and Calculating an Absorptivity Constant Laboratory Exercise 13: Determination of the Absorptivity Constant for ONP Unit Discussion UNIT V BIOLOGICAL SOLUTIONS Unit Introduction Classroom Activity 11: Getting Ready to Prepare Solutions with One Solute: Calculations Classroom Activity 12: Getting Ready to Prepare Solutions with One Solute: Ordering Chemicals Laboratory Exercise 14: Preparing Solutions with One Solute Laboratory Exercise 15: Preparing Solutions to the Correct Concentration Laboratory Exercise 16: Working with Buffers Laboratory Exercise 17: Preparing Breaking Buffer Laboratory Exercise 18: Preparing TE Buffer Laboratory Exercise 19: More Practice Making a Buffer Laboratory Exercise 20: Making a Quality Product in a Simulated Company Unit Discussion UNIT VI ASSAYS Unit Introduction Laboratory Exercise 21: Two Qualitative Assays Laboratory Exercise 22: UV Spectrophotometric Assay of DNA: Quantitative Application Laboratory Exercise 23: UV Spectrophotometric Assay of DNA and Proteins: Qualitative ApplicationsLaboratory Exercise 24: The Bradford Protein Assay: Learning the Assay Laboratory Exercise 25: The Bradford Protein Assay: Exploring Assay Verification Laboratory Exercise 26: The Beta-Galactosidase Enzyme Assay Laboratory Exercise 27: Comparing the Specific Activity of Two Preparations of Beta-GalactosidaseLaboratory Exercise 28: Using Spectrophotometry for Quality Control: Niacin Unit Discussion UNIT VII BIOLOGICAL SEPARATION METHODS Unit Introduction Classroom Activity 13: Planning for Separating Materials Using a Centrifuge Laboratory Exercise 29: Separation of Two Substances Based on Their Differential Affinities for Two Phases Laboratory Exercise 30: Separation and Identification of Dyes Using Paper Chromatography Laboratory Exercise 31: Separating Molecules by Agarose Gel Electrophoresis Laboratory Exercise 32: Using Agarose Gel Electrophoresis to Perform an Assay Laboratory Exercise 33: Optimizing Agarose Gel Electrophoresis Laboratory Exercise 34: Quantification of DNA by Agarose Gel Electrophoresis Laboratory Exercise 35: Introduction to Ion Exchange Column Chromatography Unit Discussion UNIT VIII GROWING CELLS Unit Introduction GROWING CELLS PART I: BACTERIAL CELLSLaboratory Exercise 36: Using a Compound Light Microscope Laboratory Exercise 37: Aseptic Technique on an Open Lab Bench Laboratory Exercise 38: Working with Bacteria on an Agar Substrate: Isolating Individual Colonies Laboratory Exercise 39: Gram Staining Laboratory Exercise 40: Preparing Phosphate-Buffered Saline Laboratory Exercise 41: The Aerobic Spread-Plate Method of Enumerating Colony- Forming UnitsLaboratory Exercise 42: Preparing a Growth Curve for E. coli GROWING CELLS PART 2: MAMMALIAN CELLSLaboratory Exercise 43: Aseptic Technique in a Biological Safety Cabinet Laboratory Exercise 44: Making Ham’s F12 Medium from Dehydrated Powder Laboratory Exercise 45: Examining, Photographing, and Feeding CHO Cells Laboratory Exercise 46: Counting Cells Using a Hemocytometer Laboratory Exercise 47: Subculturing CHO Cells Laboratory Exercise 48: Preparing a Growth Curve for CHO Cells Unit Discussion APPENDICES 1. Abbreviations and Acronyms Used in this Laboratory Manual 2. Glossary 3. Selected Bibliography 4. Brief Metric Review 5. Calculating Standard Deviation 6. Equipment, Supplies, and Reagents Required for Each Unit 7. Recipes and Preparation Notes
£71.99
Taylor & Francis Ltd Disinfection and Decontamination
Book SynopsisThis book describes various methods of decontamination and how the methods work. There is a discussion of the various cleaning and disinfection methods utilized, along with details of how to qualify these methods. It also describes new technologies that may be useful in the battle for decontamination across industries. Finally, this book provides a single resource on how one can address contamination issues for a variety of manufacturing processes and industries. Explores new technologies that may be useful in the battle for decontamination Examines various methods of decontamination and how the methods work Addresses contamination issues for a variety of manufacturing processes and industries Describes how to detect contaminants as well as how to deal with contaminants that are present Table of ContentsChapter 1 Introduction Chapter 2 Disinfectants and Biocides Chapter 3 Disinfecting Agents: The Art of Disinfection Chapter 4 The Microbiome and Its Usefulness to Decontamination/ Disinfection Practices Chapter 5 Disinfectant Qualification Testing Considerations for Critical Manufacturing Environments Chapter 6 Methods for Contamination Detection Chapter 7 Residue Removal in Cleanroom Environments Chapter 8 Microbiological Concerns in Non-Sterile Manufacturing Chapter 9 Preservatives and Why They Are Useful Chapter 10 The Problem of Burkholderia cepacia Complex (BCC) in Your Facility Chapter 11 What Is Mold and Why Is It Important? Chapter 12 Sterilization Methods
£45.99
Taylor & Francis Ltd Medical Devices and Human Engineering
Book SynopsisKnown as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.Medical Devices and Human Engineering, the second volume of the handbook, presents material from respected scientists with diverse backgrounds in biomedical sensors, medical instrumentation and devices, human performance engineering, rehabilitation engineering, and clinical engineering.More than three dozen specific topics are examined, including optical sensors, implantable cardiac pacemakers, electrosurgical devices, blood glucose monitoring, humancomputer interaction design, orthopedic prosthetics, clinical engineering program indicators, and virtual instruments in health care. The material is presented in a systematic manner and has been updated to rTable of ContentsBiomedical Sensors. Medical Instruments and Devices. Human Performance Engineering. Rehabilitation Engineering. Clinical Engineering.
£86.99
Taylor & Francis Ltd Biosimilars and Interchangeable Biologics
Book SynopsisWhat's the Deal with Biosimilars?Biosimilars are gaining momentum as new protein therapeutic candidates that can help fill a vital need in the healthcare industry. The biological drugs are produced by recombinant DNA technology that allows for large-scale production and an overall reduction time in costs and development. Part of a two-volume set that covers varying aspects of biosimilars, Biosimilars and Interchangeable Biologics: Strategic Elements explores the strategic planning side of biosimilar drugs and targets issues surrounding biosimilars that are linked to legal matters. This includes principal patents and intellectual property, regulatory pathways, and concerns about affordability on a global scale. It addresses the complexity of biosimilar products, and it discusses the utilization of biosimilars and related biological drugs in expanding world markets.Of specific interest to practitioners, researchers, and scientistsTable of ContentsIntroduction to Biosimilar and Interchangeable Products. Intellectual Property Issues for Biosimilars. European Regulatory Guidance. EMA-Approved Biosimilars. FDA Regulatory Guidance. ROW Regulatory Guidance. US Commercialization. Global Commercialization. Quality and Lifecycle Management.
£999.99
iUniverse Vagus Nerve Stimulation and Anxiety
Book Synopsis
£10.40
Syrawood Publishing House Bioengineering: Concepts and Applications
Book Synopsis
£87.00
ISTE Press Ltd - Elsevier Inc Multiscale Biomechanics
Book SynopsisMultiscale Biomechanics provides new insights on multiscale static and dynamic behavior of both soft and hard biological tissues, including bone, the intervertebral disk, biological membranes and tendons. The physiological aspects of bones and biological membranes are introduced, along with micromechanical models used to compute mechanical response. A modern account of continuum mechanics of growth and remodeling, generalized continuum models to capture internal lengths scales, and dedicated homogenization methods are provided to help the reader with the necessary theoretical foundations. Topics discussed include multiscale methods for fibrous media based on discrete homogenization, generalized continua constitutive models for bone, and a presentation of recent theoretical and numerical advances. In addition, a refresher on continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods is given in separate chapters. Numerical aspects are treated in detail, and simulations are presented to illustrate models. This book is intended for graduate students and researchers in biomechanics interested in the latest research developments, as well as those who wish to gain insight into the field of biomechanics.Table of ContentsPart 1. Theoretical Basis: Continuum Mechanics, Homogenization Methods, Thermodynamics of Growing Solid Bodies 1. Tensor Calculus Jean-François GANGHOFFER 2. Continuum Mechanics Jean-François GANGHOFFER 3. Constitutive Models of Soft and Hard Living Tissues Jean-François GANGHOFFER 4. Discrete Homogenization of Network Materials Jean-François GANGHOFFER and Khaled EL NADY 5. Mechanics and Thermodynamics of Volumetric and Surface Growth Jean-François GANGHOFFER Part 2. Multiscale Bone Mechanics 6. Micropolar Models of Trabecular Bone Jean-François GANGHOFFER and Ibrahim GODA 7. Size-Dependent Dynamic Behavior of Trabecular Bone Jean-François GANGHOFFER, Ibrahim GODA, Rachid RAHOUADJ 8. Prediction of Size Effects in Bone Brittle and Plastic Collapse Jean-François GANGHOFFER and Ibrahim GODA 9. Multiscale Aspects of Bone Internal and External Remodeling Jean-François GANGHOFFER and Ibrahim GODA 10. Integrated Remodeling to Fatigue Damage Model of Bone Jean-François GANGHOFFER and Ibrahim GODA Part 3. Mechanics of Soft Biological Tissues: The Intervertebral Disk, Biological Networks, Ligaments and Tendons 11. Micromechanics of the Intervertebral Disk Adrien BALDIT 12. Effective Mechanical Response of Biological Membranes Khaled EL NADY, Jean-François GANGHOFFER and Ibrahim GODA 13. Micromechanics of Ligaments and Tendons Cédric LAURENT
£111.75
Collective Ink Transhuman Citizen
Book SynopsisHow Far Would You Go to Stay Alive?
£15.29
Logos Press Building the Case for Biotechnology: Management
Book Synopsis
£999.99
Springer International Publishing AG Biotransformations in Organic Chemistry: A
Book SynopsisThis well-established textbook on biocatalysis provides a basis for undergraduate and graduate courses in modern organic chemistry, as well as a condensed introduction into this field. After a basic introduction into the use of biocatalysts—principles of stereoselective transformations, enzyme properties and kinetics—the different types of reactions are explained according to the 'reaction principle', such as hydrolysis, reduction, oxidation, C–C bond formation, etc. Special techniques, such as the use of enzymes in organic solvents, immobilization techniques, artificial enzymes and the design of cascade-reactions are treated in a separate section. A final chapter deals with the basic rules for the safe and practical handling of biocatalysts.The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective transformations for state-of-the-art synthetic organic chemistry. Over the last two decades, this methodology has become an indispensable tool for asymmetric synthesis, not only at the academic level, but also on an industrial scale. In this 7th edition new topics have been introduced which include alcohol and amine oxidases, amine dehydrogenases, imine reductases, haloalkane dehalogenases, ATP-independent phosphorylation, Michael-additions and cascade reactions. This new edition also emphasizes the use of enzymes in industrial biotransformations with practical examples.Table of Contents1 Introduction and Background Information1.1 Introduction..........................................................................................1.2 Common Prejudices Against Enzymes...............................................1.3 Advantages and Disadvantages of Biocatalysts..................................1.3.1 Advantages of Biocatalysts........................................................1.3.2 Disadvantages of Biocatalysts...................................................1.3.3 Isolated Enzymes vs. Whole Cell Systems.........................1.4 Enzyme Properties and Nomenclature...............................................1.4.1 Structural Biology in a Nutshell..............................1.4.2 Mechanistic Aspects of Enzyme Catalysis...........................1.4.3 Classification and Nomenclature............................................1.4.4 Coenzymes.......................................................................1.4.5 Enzyme Sources..............................................................References..... ................................................................................... 2 Biocatalytic Applications 2.1 Hydrolytic Reactions..........................................................................2.1.1 Mechanistic and Kinetic Aspects.............................................2.1.2 Hydrolysis of the Amide Bond................................................2.1.3 Ester Hydrolysis.......................................................................2.1.3.1 Esterases and Proteases.............................................2.1.3.2 Lipases.......................................................................2.1.3.3 Hydrolysis of Lactones.......................................................................2.1.4 Hydrolysis and Formation of Phosphate Esters......................2.1.5 Hydrolysis of Epoxides...........................................................2.1.6 Hydrolysis of Nitriles..............................................................2.2 Reduction Reactions..........................................................................2.2.1 Recycling of Cofactors............................................................2.2.2 Reduction of Aldehydes and Ketones Using Isolated Enzymes.....................................................2.2.3 Reduction of Aldehydes and Ketones Using Whole Cells....2.2.4 Reduction of C=N Bonds .......................2.2.5 Reduction of C=C-Bonds .......................2.3 Oxidation Reactions..........................................................................2.3.1 Oxidation of Alcohols and Aldehydes...................................2.3.2 Oxidation of Amines ...................................2.3.3 Oxygenation Reactions...........................................................2.3.3.1 Hydroxylation of Alkanes........................................2.3.3.2 Hydroxylation of Aromatic Compounds.................2.3.3.3 Epoxidation of Alkenes............................................2.3.3.4 Sulfoxidation Reactions............................................2.3.3.5 Baeyer-Villiger Reactions.........................................2.3.3.6 Formation of Hydroperoxides.............................................2.3.3.7 Dihydroxylation of Aromatic Compounds and Conjugated C=C Bonds...............2.3.4 Peroxidation Reactions............................................................2.4 Formation of Carbon-Carbon Bonds.................................................2.4.1 Aldol Reactions.......................................................................2.4.2 Thiamine-Dependent Acyloin and Benzoin Reactions.........2.5 Addition and Elimination Reactions.................................................2.5.1 Addition of Water........................................................2.5.2 Addition of Ammonia..........................................................2.5.3 Cyanohydrin Formation and Henry Reaction...........................................2.5.4 Michael-Type Additions............................................2.6 Transfer Reactions.............................................................2.6.1 Glycosyl Transfer Reactions..............................................2.6.1.1 Glycosyl Transferases........................................2.6.1.2 Glycoside phosphorylases and Trans-glycosidases........................................2.6.1.3 Glycosidases........................................2.6.2 Amino Transfer Reactions...................................................2.7 Halogenation and Dehalogenation Reactions...................................2.7.1 Halogenation...........................................................................2.7.2 Dehalogenation.......................................................................References....................................................................................... 3 Special Techniques 3.1 Enzymes in Organic Solvents..........................................................3.1.1 Ester Synthesis........................................................................3.1.2 Lactone Synthesis...................................................................3.1.3 Amide Synthesis.....................................................................3.1.4 Peptide Synthesis....................................................................3.1.5 Peracid Synthesis....................................................................3.1.6 Redox Reactions.....................................................................3.1.7 Medium Engineering...............................................................3.2 Cascade Reactions...............................................................3.3 Immobilization..................................................................................3.4 Artificial and Modified Enzymes.....................................................3.4.1 Artificial Enzyme Mimics.....................................................3.4.2 Modified Enzymes.......................................................... 3.4.2.1 Chemically Modified Enzymes................................3.4.2.2 Genetically Modified Enzymes................................3.4.3 Catalytic Antibodies................................................................References........................................................................................ 4 State of the Art and Outlook................................................................. 5 Appendix 5.1 Basic Rules for Handling Biocatalysts..............................................5.2 Abbreviations....................................................................................5.3 Suppliers of Enzymes.......................................................................5.4 Commonly Used Enzyme Preparations...........................................5.5 Major Culture Collections................................................................5.6 Pathogenic Bacteria and Fungi........................................................
£67.49
MP-WIS Uni of Wisconsin Biotechnology
Book SynopsisThis volume teaches 100 ""kanji"" that appear frequently in documents dealing with biotechnology and reviews the 365 ""kanji"" presented in ""Basic Technical Japanese"". The lessons are keyed to the final ten chapters of the latter, enabling students to use the two volumes together.
£24.95
John Wiley & Sons Medical Instrumentation
Book Synopsis
£187.20
Rlpg/Galleys Science Virtue and the Future of Humanity
Book SynopsisThis book is an accessible and profound introduction to the key issues facing our country in our biotechnological age. Leading public intellectuals bring to bear a wide and deep learning on particular issues of public policy and discuss the relationship between technological and moral progress that takes place over the course of a human life.Trade ReviewThis is a book about the future—the future of liberty, love, and learning in a scientific age. Ranging from the techno-utopian to the techno-wary, the authors explore the possible shape of the world to come. Can we expect an unbounded, creative future? Or is it true, as Abraham Lincoln said, that ‘This is a world of compensations,’ a world where both human and cosmic nature (not to mention divine justice) set limits and establish relations that have a logic all their own? If even robots need morality, as the AI theorists are beginning to realize, then we really are ‘stuck with virtue.’ This insightful and eloquent collection helps us think more deeply about permanence in the midst of change. -- Diana J. Schaub, Loyola University MarylandTable of ContentsIntroduction. Observations on American Liberty: My Report from the Front, Peter Augustine Lawler Chapter 1. Pensions and Health Care in an Aging Society, James C. Captretta Chapter 2. The Demographic Challenge to Entitlements: A Comment, Criticism, and Caveat, William English Chapter 3. An Earned Humility: Reflections on Professional Obligations to the Living Kidney Donor, Benjamin Hippen Chapter 4. The Science of Politics and the Conquest of Nature, Patrick J. Deneen Chapter 5. The Problem with 'Friendly' Artificial Intelligence, Adam Keiper and Ari N. Schulman Chapter 6. The Case for Enhancing People, Ronald Bailey Chapter 7. Justice without Foundations, Robert P. Kraynak Chapter 8. Blame It on My Genotype (if Not My Criminal Brain): Materialist Metaphysics and the Loss of Human Dignity, J. Daryl Charles Chapter 9. Libertarians vs. Liberal Learning, Peter Augustine Lawler Chapter 10. Machine Morality and Human Responsibility, Charles T. Rubin Chapter 11. Tocqueville on Technology, Benjamin Storey Chapter 12. The Place of Liberal Education in Contemporary Higher Education, Marc D. Guerra
£91.80
Rowman & Littlefield Publishers The Ethics of Food
Book SynopsisFood makes philosophers of us all. Death does the same . . . but death comes only once . . . and choices about food come many times each day. In The Ethics of Food, Gregory E. Pence brings together a collection of voices who share the view that the ethics of genetically modified food is among the most pressing societal questions of our time. This comprehensive collection addresses a broad range of subjects, including the meaning of food, moral analyses of vegetarianism and starvation, the safety and environmental risks of genetically modified food, issues of global food politics and the food industry, and the relationships among food, evolution, and human history. Will genetically modified food feed the poor or destroy the environment? Is it a threat to our health? Is the assumed healthfulness of organic food a myth or a reality? The answers to these and other questions are engagingly pursued in this substantive collection, the first of its kind to address the broad range of philosophiTrade ReviewAn excellent introduction for undergraduates. A broad range of problems is treated in an engaging and lucid manner. Nice bibliographies. -- Dr. S. N. Fratantaro, Providence CollegeNicely produced. * Food Science and Technology *Both the publishers and the editor are to be commended for bringing together such diverse viewpoints in one, easy-to-read volume. * Experimental Agriculture *The reader is led to compellingly consider the pressing issues of starvation, the consumption of meat and the benefits and dangers of genetically modified food. * Science and Theology News *Finally, we have a book that speaks to one of the most pressing, though under-examined, issues in our biotech age. Greg Pence has produced, again, a stimulating and timely text. Crisp and comprehensive in its approach, The Ethics of Food takes stock of the morally imperative questions surrounding food production, modification, and consumption, particularly their global impact upon ecosystems. The text offers a judicious menu of readings that articulate differing perspectives from various fields. Combining scholarship and access, this pioneering work insightfully underscores the ongoing tension between food biotechnologies and biodiversity, compelling us to move toward reasonable resolutions. -- Michael Brannigan, executive director, Center for the Study of Ethics, La Roche CollegeTable of ContentsPart 1 Part I: The Meaning of Food Chapter 2 A Thing Shared Chapter 3 How We Grow Food Reflects Our Virtues and Vices Part 4 Part II: Eating Meat Chapter 5 Animal Liberation and Vegetarianism Chapter 6 Meat Is Good for You Part 7 Part III: Starvation Chapter 8 Lifeboat Ethics: The Case against Helping the Poor Chapter 9 Golden Rice Is Fool's Gold Chapter 10 Are We Going Mad? Part 11 Part IV: Safety of Genetically Modified Foods Chapter 12 The Unholy Alliance Chapter 13 The FDA's Volte-Face on Food Biotech Chapter 14 Dr. Strangelunch: Why Should We Learn to Love Genetically Modified Food Part 15 Part V: Benefits / Dangers of Organic Food Chapter 16 Organically or Genetically Modified Food: Which Is Better? Chapter 17 The Benefits of Organic Food Part 18 Part VI: Genetically Modified Food and Environmental Risks Chapter 19 Genetic Engineering and Food Security Chapter 20 GM Is the Best Option We Have Part 21 Part VII: Food Biotechnology and Nature Chapter 22 Biotechnology's Negative Impact on World Agriculture Chapter 23 The Population / Diversity Paradox: Agricultural Efficiency to Save Wilderness Part 24 Part VIII: Global Food Politics and Economics Chapter 25 A Removable Feast Chapter 26 From Global to Local: Sowing the Seeds of Community Part 27 Part IX: The Food Industry Chapter 28 The Hamburger Bacteria Chapter 29 The United States Food Safety System
£107.10
Rowman & Littlefield Publishers The Ethics of Food
Book SynopsisFood makes philosophers of us all. Death does the same . . . but death comes only once . . . and choices about food come many times each day. In The Ethics of Food, Gregory E. Pence brings together a collection of voices who share the view that the ethics of genetically modified food is among the most pressing societal questions of our time. This comprehensive collection addresses a broad range of subjects, including the meaning of food, moral analyses of vegetarianism and starvation, the safety and environmental risks of genetically modified food, issues of global food politics and the food industry, and the relationships among food, evolution, and human history. Will genetically modified food feed the poor or destroy the environment? Is it a threat to our health? Is the assumed healthfulness of organic food a myth or a reality? The answers to these and other questions are engagingly pursued in this substantive collection, the first of its kind to address the broad range of philosophiTrade ReviewAn excellent introduction for undergraduates. A broad range of problems is treated in an engaging and lucid manner. Nice bibliographies. -- Dr. S. N. Fratantaro, Providence CollegeNicely produced. * Food Science and Technology *Both the publishers and the editor are to be commended for bringing together such diverse viewpoints in one, easy-to-read volume. * Experimental Agriculture *The reader is led to compellingly consider the pressing issues of starvation, the consumption of meat and the benefits and dangers of genetically modified food. * Science and Theology News *Finally, we have a book that speaks to one of the most pressing, though under-examined, issues in our biotech age. Greg Pence has produced, again, a stimulating and timely text. Crisp and comprehensive in its approach, The Ethics of Food takes stock of the morally imperative questions surrounding food production, modification, and consumption, particularly their global impact upon ecosystems. The text offers a judicious menu of readings that articulate differing perspectives from various fields. Combining scholarship and access, this pioneering work insightfully underscores the ongoing tension between food biotechnologies and biodiversity, compelling us to move toward reasonable resolutions. -- Michael Brannigan, executive director, Center for the Study of Ethics, La Roche CollegeTable of ContentsPart 1 Part I: The Meaning of Food Chapter 2 A Thing Shared Chapter 3 How We Grow Food Reflects Our Virtues and Vices Part 4 Part II: Eating Meat Chapter 5 Animal Liberation and Vegetarianism Chapter 6 Meat Is Good for You Part 7 Part III: Starvation Chapter 8 Lifeboat Ethics: The Case against Helping the Poor Chapter 9 Golden Rice Is Fool's Gold Chapter 10 Are We Going Mad? Part 11 Part IV: Safety of Genetically Modified Foods Chapter 12 The Unholy Alliance Chapter 13 The FDA's Volte-Face on Food Biotech Chapter 14 Dr. Strangelunch: Why Should We Learn to Love Genetically Modified Food Part 15 Part V: Benefits / Dangers of Organic Food Chapter 16 Organically or Genetically Modified Food: Which Is Better? Chapter 17 The Benefits of Organic Food Part 18 Part VI: Genetically Modified Food and Environmental Risks Chapter 19 Genetic Engineering and Food Security Chapter 20 GM Is the Best Option We Have Part 21 Part VII: Food Biotechnology and Nature Chapter 22 Biotechnology's Negative Impact on World Agriculture Chapter 23 The Population / Diversity Paradox: Agricultural Efficiency to Save Wilderness Part 24 Part VIII: Global Food Politics and Economics Chapter 25 A Removable Feast Chapter 26 From Global to Local: Sowing the Seeds of Community Part 27 Part IX: The Food Industry Chapter 28 The Hamburger Bacteria Chapter 29 The United States Food Safety System
£49.50
Rowman & Littlefield Publishers Ethical Issues in Biotechnology
Book SynopsisEthical Issues in Biotechnology is the first textbook of its kind, written collaboratively by a philosopher and a biologist to provide undergraduate students with a comprehensive, accessible introduction to the ethical and scientific fundamentals of biotechnology. Engaging the ethics and the science side by side, the text addresses pressing questions in agricultural, food, and animal biotechnology; human genetics; gene therapy; human cloning; and stem cell research. A general introduction to both the moral philosophy and fundamentals of genetics is enhanced throughout the text with section-specific introductions addressing the particular philosophical and scientific challenges posed by the topic under consideration. Diagrams and drawings, study cases, liberal use of practical examples, and suggestions for further reading make the text an ideal resource for a broad range of students interested in issues and questions lying at the intersection of philosophy and genetics.Trade ReviewThis will be the field-defining book for the ethics of biotechnology. It is the best one-volume guide to the issues currently being debated with respect to the new genetic technologies, and the only one that illuminates the connections between medical and agricultural applications. Teachers will use it in the classroom, but beyond that it should be thought of as an indispensable read for anyone who wants to be informed about science, ethics, and public policy. -- Paul B. Thompson, Michigan State University, W.K. Kellogg Professor of Agricultural, Food, and Community EthicsRichard Sherlock and John Morrey have developed a timely anthology on the ethical dimensions in biotechnology that is both scientifically sound and philosophically provocative. Engaging readings as well as a compendium of cases offer many formats for teachable dialogue between instructor and students. The questions—scientific, philosophical, political, legal, moral—examined through Ethical Issues in Biotechnology illustrate the urgent need for critical ethical scholarship in this rapidly emerging field. This anthology meets that need. -- Courtney S. Campbell, Oregon State UniversityThe most substantial and sophisticated treatment of biomedical ethics that I have come across recently, and a treatment that remains quite accessible to undergraduate students. -- Dr. S. N. Fratantaro, Providence CollegeIt is refreshingly atypical that the book does not just focus on human cloning or human genetic screening but takes on the whole topic of biotechnology. It is enterprising and clever to have a book edited collaboratively by a biologist and a philosopher, and the result is a balanced treatment. The readings have already been proven successful with students. With diagrams, study cases, examples, and suggestions for further research, the book is a comprehensive and well-expressed introduction to the science and ethics of biotechnology. * Research News and Opportunities In Science and Theology *All who are involved in ethics and biotechnology should be immensely grateful for [Sherlock and Morrey's] efforts. Balanced and teachable, Ethical Issues in Biotechnology is a valuable contribution to the field, and a must-have for those teaching either undergraduates enrolled in upper-level courses, or graduates students, across the disciplines of science and humanities. * Technology and Culture *Sherlock and Morrey cover a fascinating and engaging set of cutting edge issues. This work covers biotechnology in the broadest sense of the word, contains masterfully selected readings, and challenges the reader to think into the future. It should be very useful to college, graduate, and professional students. -- Steven Post, Case Western Reserve UniversityTable of ContentsChapter 1 Introduction Part 2 I. Fundamental Issues of Ethics and Biotechnology Chapter 3 How to Assess the Consequences of Genetic Engineering Chapter 4 Redesigning the World: Ethical Questions About Genetic Engineering Chapter 5 "Playing God" and Invoking a Perspective Chapter 6 Genetic Trespassing and Environmental Ethics Part 7 II. Agricultural Biotechnology Chapter 8 Differing Views of the Benefits and Risks of Agricultural Biotechnology Chapter 9 Risk and Risk Management Chapter 10 Journey to the Origin: Biological Integrity and Agriculture Chapter 11 Three Concepts of Genetic Trespassing Chapter 12 Ten Reasons Why Biotechnology Will Be Important to the Developing World Chapter 13 Ten Reasons Why Biotechnology Will Not Ensure Food Security, Protect the Environment, or Reduce Poverty in the Developing World Part 14 III. Food Biotechnology Chapter 15 The Scientific and Health Aspects of Genetically Modified Foods: Rapporteurs' Summary Chapter 16 The Safety of Foods Developed by Biotechnology Chapter 17 Hazards of Genetically Engineered Foods and Crops: Why We Need a Global Moratorium Chapter 18 Why We Need Labeling of Genetically Engineered Food Chapter 19 Ethical Issues in Food Biotechnology Part 20 IV. Animal Biotechnology Chapter 21 A Critical View of the Genetic Engineering of Farm Animals Chapter 22 The "Frankenstein Thing": The Moral Impact of Genetic Engineering of Agricultural Animals on Society and Future Science Chapter 23 On the Ethics of Using Animals for Human Benefit Chapter 24 The Case for the Use of Animals in Biomedical Research Chapter 25 Artificial Lives: Philosophical Dimensions of Farm Animal Biotechnology Chapter 26 Genetic Engineering as Animal Slavery Chapter 27 Uncertainty in Xenotransplantation: Individual Benefit versus Collective Risk Chapter 28 Critical Ethical Issues in Clinical Trials with Xenotransplants Part 29 V. Human Genetic Testing and Therapy Chapter 30 Social, Legal, and Ethical Implications of Genetic Testing Chapter 31 Genetic Links, Family Ties, and Social Bonds: Rights and Responsibilities in the Face of Genetic Knowledge Chapter 32 Privacy and the Control of Genetic Information Chapter 33 The Ethics of Somatic Cell Gene Therapy Chapter 34 Human Inheritable Genetic Modifications: Assessing Scientific, Ethical, Religious, and Policy Issues Chapter 35 Germ-Line Genetic Engineering and Moral Diversity: Moral Controversies in a Post-Christian World Part 36 VI. Human Cloning and Stem Cell Research Chapter 37 Human Cloning: Report and Recommendations of the Natioanl Bioethics Advisory Commission Chapter 38 The Wisdom of Repugnance Chapter 39 Genetic Encores: The Ethics of Human Cloning Chapter 40 Stem Cell Research and Applications: Findings and Recommendations Chapter 41 On Human Embryos and Stem Cell Research: An Appeal for Legally and Ethically Responsible Science and Public Policy Chapter 42 Suggestions for Further Study Chapter 43 Study Cases
£71.00
Institute of Physics Publishing Zerodimensional Carbon Nanomaterials
Book SynopsisThisbook covers the latest advances in zero-dimensional nanomaterials, with a focuson carbon quantum dots (CQDs) and graphene quantum dots (GQDs). Providing acomprehensive reference for researchers, postgraduates and industry practitionersworking on zero-dimensional carbon nanomaterials, this text brings together themost recently available data to support researchers in this rapidly developingfield.
£108.00
IOP Publishing Organ Printing Second Edition
Book Synopsis
£23.75
Institute of Physics Publishing Organ Printing Second Edition
Book Synopsis
£108.00
Institute of Physics Publishing Introduction to Pharmaceutical Biotechnology
Book Synopsis
£23.75
Ohio State University Press Bodies of Technology Womens Involvement with
Book Synopsis
£37.06
University of Alabama Press Brutes or Angels Human Possibility in the Age of
Book SynopsisBrutes or Angels provides basic information on a wide array of new technologies in the life sciences, along with the ethical issues raised by each.
£26.96
Royal Society of Chemistry Heat Capacities
Book SynopsisThe book contains the very latest information on all aspects of heat capacities related to liquids and vapours, either pure or mixed. The chapters, all written by knowledgeable experts in their respective fields, cover theory, experimental methods, and techniques (including speed of sound, photothermal techniques, brillouin scattering, scanning transitiometry, high resolution adiabatic scanning calorimetry), results on solutions, liquids, vapours, mixtures, electrolytes, critical regions, proteins, liquid crystals, polymers, reactions, effects of high pressure and phase changes. Experimental methods for the determination of heat capacities as well as theoretical aspects, including data correlation and prediction, are dealt with in detail. Of special importance are the contributions concerning heat capacities of dilute solutions, ultrasonics and hypersonics, critical behaviour and the influence of high pressure. This new book covers the wide range of topics in the field of heat capacitiTrade Review"This book features 22 chapters from an international team of acknowledged experts from a variety of disciplines who describe the current state of the art in heat capacities related to liquids, solutions and vapours." * JACS, 2010, 132, 18430 *The coverage by an international team of 35 authors, is wide-ranging This book will be welcomed by researchers in chemical thermodynamics in academia and in the chemical industry. * Journal of Thermal Analysis and Calorimetry - JOhn Dymond *Table of ContentsChapter 1: Heat Capacities: Introduction, Concepts and Selected Applications; Chapter 2: Calorimetric Methods for Measuring Heat Capacities of Liquids and Liquid Solutions; Chapter 3: An Exact Analysis of Conductive Heat Losses in a Flow Calorimeter for Heat capacity Measurement; Chapter 4: Excess Heat Capacities and Related Properties of Liquid mixtures; Chapter 5: Heat Capacity of Non-Electrolyte Solutions; Chapter 6: Heat Capacities and Related Properties of Vapours and Vapour Mixtures; Chapter 7: Heat Capacity of Electrolyte Solutions; Chapter 8: Scanning Transitiometry and its Use to Determine Heat Capacities of Liquids at High Pressures; Chapter 9: Chapter 9 Sound Speed Measurements and Heat Capacities of gases; Chapter 10: Speed of Sound Measurements and Heat Capacities of Liquid Systems at High Pressure; Chapter 11: Heat Capacities and Brillouin Scattering in Liquids; Chapter 12: Photothermal Techniques for Heat Capacities; Chapter 13: High Resolution Adiabatic Scanning Calorimetry and Heat Capacities; Chapter 14: Heat Capacities in the Critical Region; Chapter 15: Heat Capacity of Polymeric Systems; Chapter 16: Protein Heat Capacity; Chapter 17: Specific Heat in Liquid Crystals; Chapter 18: Heat Capacities and Phase Transitions for the Dynamic Chemical Systems: Conformers, Tautomers, Plastic Crystals and Ionic Liquids; Chapter 19: The Estimation of Heat Capacities of Pure Liquids; Chapter 20: Computer Simulation Studies of Heat Capacity Effects Associated with Hydrophobic Effects; Chapter 21: Partial Molar Heat Capacities of Gases Dissolved in Liquid; Chapter 22: Heat Capacities of Molten Salts
£114.00
Royal Society of Chemistry Dendrimers in Medicine and Biotechnology
Book SynopsisDendrimers are a new class of macromolecule increasingly used in the fields of synthetic organic chemistry, biology, medicine and biotechnology. Dendrimers in Medicine and Biotechnology: New Molecular Tools looks at this exciting and rapidly growing area of science. Using an interdisciplinary approach with particular emphasis on biological applications, the book discusses the relationship between the dendrimer molecular motif and its biological properties. A general introduction to the subject of dendrimers, including definitions of terms and symbols, is provided. Subsequent sections discuss topics including dendrimers in biological systems, dendrimers as drug delivery devices, dendrimers in diagnostics and dendrimer drugs. Throughout the book examples from current research are also provided. This book will appeal to a wide range of scientists, including non specialists who require an introduction to dendrimers, as well as those wishing to know more about the application of dendrimersTrade ReviewOverview of the state-of-the-art in a rapidly moving research.....be essential reading for graduates and academics involved in research in the area. * Chemistry and Industry, 6th November 2006 (David Smith) *"This book is, indeed, a very timely account of various aspects of the chemical and biological properties of dendrimers, which make them such a versatile tool both for fundamental research and applied biochemistry." "Dendrimers are still in their infancy, but they attract more and more attention of scientists from various disciplines, and this book will be a very helpful tool for those who are already well familiar or only starting to become acquainted with them." -- Natalia Nalivaeva, University of Leeds * The Biochemist Evolution website *Table of ContentsChapter 1: Dendrimers: Design, synthesis and chemical properties; 1.1: Introduction; 1.2: Terms and nomenclature in dendrimer chemistry; 1.3: Dendrimer design; 1.4: Dendrimer synthesis; 1.5: Physicochemical properties of dendrimers; 1.6: Summary; Chapter 2: Properties of dendrimers in biological systems; 2.1: Significance of multivalent binding in biological interactions; 2.2: Biocompatibility of dendrimers; 2.3: Summary; Chapter 3: Dendrimers as drug delivery devices; 3.1: Introduction; 3.2: Dendrimer hosts; 3.3: Covalently bound dendrimer conjugates; 3.4: Dendrimers as gene transfer reagents; 3.5: Summary; Chapter 4: Dendrimer drugs; 4.1: Introduction; 4.2: Antiviral dendrimers; 4.3: Antibacterial dendrimers; 4.4: Dendrimers in antitumor therapy; 4.5: Dendrimer in therapy of other diseases; 4.6: Dendrimer based vaccines; 4.7: Dendrimer interactions with proteins. Solubilisation of protein aggregates; 4.7: Summary; Chapter 5: Dendrimers in diagnostics; 5.1: Contrast agents based on dendrimers; 5.2: Fluorescence enhanced by dendrimers; 5.3: Dendrimers in bioassays; 5.4: Summary; Chapter 6: Dendrimers as biomimics; 6.1: Introduction; 6.2: Deddrimers as protein mimics; 6.3: Dendrimers as artificial enzymes; 6.4: Dendrimers as artificial antigens, antibodies and cell surfaces; 6.5: Summary;
£70.29
Royal Society of Chemistry Wheat Gluten
Book SynopsisBread, pasta, noodles ... some of the many ways in which humans consume wheat after processing has taken place. The gluten proteins of wheat grain, which determine the processing properties of wheat flour, have been the subject of intensive study for many years. The structures, genetics and functional properties of this unique group of proteins are the focus of this book. Providing a unique snapshot of the most exciting current research in the area, this wide-ranging book encompasses topics such as biotechnology; analysis, purification and characterization; quality testing; and environmental impacts. Contributions come from academia, government laboratories and industry throughout the world, and will be welcomed by practitioners in a variety of fields including the food, biological and agricultural sciences.Trade Review"... a valuable contribution to the literature of cereal science ..." * Food Science and Technology, Vol 15, Issue 4, p 65, 2001 *"... invaluable to researchers in wheat quality for keeping up to date." * Chemistry and Industry, Issue 1, 7 January 2002, p 18-19 *Table of ContentsGenetics and Quality Correlations; Biotechnology; Gluten Protein Analysis, Purification and Characterization; Disulphide Bonds and Redox Reactions; Improvers and Enzymic Modification; Quality Testing, Non-Food Uses; Viscoelasticity, Rheology and Mixing; Gluten Protein Synthesis during Grain Development and Effects of Nutrition and Environment; Non-Gluten Components; Subject Index.
£999.99
Royal Society of Chemistry Food Flavors and Chemistry
Book SynopsisFood may be nutritious, visually appealing and easy to prepare but if it does not possess desirable flavors, it will not be consumed. Food Flavors and Chemistry: Advances of the New Millennium primarily focuses on food flavors and their use in foods. Coverage also includes other important topics in food chemistry and production such as analytical methods, packaging, storage, safety and patents. Positive flavor notes are described, including ways of enhancing them in food. Conversely, methods for eliminating and reducing undesirable flavors are also proposed. Packaging aspects of foods, with respect to controlling sensory attributes, appearance and microbiological safety are discussed in detail. There is also a section concentrating on the most recent developments in dairy flavor chemistry. This book will be an important read for all postgraduate students, academics and industrial researchers wanting to keep abreast of food flavors and their chemistry.Trade Review"... a good buy for an academic or industry library, given its wide coverage." * Chemistry & Industry, Issue 2, p 21, 20 January 2003 *"... a valuable addition to the area of food flavour science ..." * Journal of the Science for Food and Agriculture, Vol 83, Issue 4, March 2003 *"... a vital acquisition for all those interested in food and flavour composition, stability and packaging ..." * Chromatographia, Vol 59, January 2004, p 141 *Table of ContentsOverview; Dairy and Wine Flavors; Composition; Formation of Flavors; Analysis; Antioxidants and Health; Quality; Subject Index.
£85.45
Taylor & Francis Ltd Nanomedicine
Book SynopsisThe book is an introduction to nanomedicine informed by a philosophical reflection about the domain and recent developments. It is an overview of the field, sketching out the main areas of current investment and research. The authors present some case-studies illustrating the different areas of research (nanopharmacy, theranostics and patient monitoring) as well as reflecting on the risks that accompany it, such as unanticipated impacts on human health and environmental toxicity. This introduction to a fast-growing field in modern medical research is of great interest to researchers working in many disciplines as well as the general public. In addition to an overview of the work currently ongoing, the authors critically assess these projects from an ethical and philosophical perspective.Key Features Provides an overview of nanomedicine Employs a reflective and coherent critical evaluation of the benefits and risks of nanomedicine Table of Contents Authors. Introduction. Nanopharmacy: What's New With the Nano? Theranostics: Toward a New Integrative Horizon. Health Under Surveillance. Genetic Nanomedicine. Toxicology of Nanomaterials: A New Toxicology? Organs on Chips, Miniaturization and Medical Specialties: The Different Logics of Nanomedicine. Regenerative Medicine: Mobilizing the Body's Own Repair Mechanisms: Conclusion. Glossary. Index.
£195.00
Wiley Biotechnology and Biopharmaceuticals
Book SynopsisBiotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs, Second Edition addresses the pivotal issues relating to translational science, including preclinical and clinical drug development, regulatory science, pharmaco-economics and cost-effectiveness considerations. The new edition also provides an update on new proteins and genetic medicines, the translational and integrated sciences that continue to fuel the innovations in medicine, as well as the new areas of therapeutic development including cancer vaccines, stem cell therapeutics, and cell-based therapies.Trade Review“Overall, this book provides a valuable resource that can be utilized as a quick look-up guide and, more importantly, as an educational tool that can be used in strategic planning. The presentation style provides comprehensive information amenable to a diverse audience.” (Clinical Infectious Diseases, 30 October 2014)Table of ContentsContributors xiii Foreword xv Preface xvii Preface to the First Edition xix Acknowledgments xxi Organization of the Book xxiii User Agreement xxv Part I Transforming Proteins and Genes into Drugs—The Science and the Art 1 1 Introduction to Biopharmaceuticals 3 Abstract 3 1.1 Background and Significance 4 1.2 Translation of Biotechnology for Developing Biopharmaceuticals 7 1.3 Historical Perspective of Pharmaceutical Biotechnology 8 1.4 Distinctions between Chemical Drugs Versus Biopharmaceuticals 8 1.5 Summary 10 2 Distinctions of Biologic Versus Small Molecule Platforms in Drug Development 13 Abstract 13 2.1 Introduction 14 2.2 Transforming New Molecules into Drugs: The Drug Development Process 14 2.3 Key Differences between Biotechnology and Chemical Products 16 2.4 Current Trends in Drug Development 18 2.5 Summary 22 3 Financing Biologic Drug Development 23 Abstract 23 3.1 Introduction 24 3.2 The Role of the Orphan Drug Act 27 3.3 Clinical Leverage Strategy in Accelerating Drug Development 30 3.4 Therapeutic Target Considerations 32 3.5 Evolving Trends 34 3.6 Summary 36 4 Application of Biotechnology in Drug Discovery and Early Development 39 Abstract 39 4.1 Introduction 40 4.2 Data Mining, Molecular Cloning, and Characterization 40 4.3 Optimization of Cell Expression Systems and Product Yield 50 4.4 Molecular Optimization 51 4.5 Proteins and Genes as Targets for Drug Discovery and Development 56 4.6 Summary 58 5 Large-Scale Production of Recombinant Proteins 63 Abstract 63 5.1 Introduction 64 5.2 Yield Optimization in Genetic Constructs and Host Cells 65 5.3 Large-Scale Cultivation of Host Cells 66 5.4 Downstream Processing and Purification 70 5.5 Quality Assurance and Quality Control 75 5.6 Summary 77 6 Clinical Pharmacology, Toxicology, and Therapeutic Dosage and Response 79 Abstract 79 6.1 Introduction 80 6.2 Clinical Pharmacology and Toxicology 80 6.3 Dose and Therapeutic Response 95 6.4 Dosage Form and Route of Administration 97 6.5 Summary 99 7 Clinical Evaluation and Regulatory Approval and Enforcement of Biopharmaceuticals 103 Abstract 103 7.1 Introduction: Biologic Drug Development and Approval 104 7.2 Licensing of Biological Products 104 7.3 Preclinical and Clinical Testing 107 7.4 FDA Review and Approval Process 114 7.5 Regulatory Enforcement 118 7.6 Globalization of Drug Approval (Chien*) 118 7.7 Summary 122 8 Pharmacoeconomics and Drug Pricing (Garrison*) 125 Abstract 125 8.1 Introduction: Pharmacoeconomics 126 8.2 Cost-Effectiveness: Assessing the Value of Biopharmaceuticals 126 8.3 The Cost of Developing Biopharmaceuticals 128 8.4 Pricing Biopharmaceuticals 131 8.5 Drug Development Incentives 133 8.6 Economics of Biosimilars 133 8.7 Economic Impact of Personalized Medicine 134 8.8 Summary and Future Challenges 135 Part II Therapeutic and Clinical Applications of Biopharmaceu ticals—Proteins and Nucleic Acids 137 9 Antibodies and Derivatives 139 Abstract 139 Section One 140 9.1 Molecular Characteristics and Therapeutic Applications 140 9.1.1 Introduction 140 9.1.2 Historical Perspective—Discovery, Classification, Biodistribution, and Physiological Characteristics of Antibody Molecules 140 9.1.3 Gamma Globulin and Hyperimmune Globulin 144 9.1.4 Monoclonal Antibodies—From Mouse, Mouse-Human Chimeric, Humanized, to Human Monoclonal Antibodies 145 9.1.5 Antibody Derivatives 147 9.1.6 Disposition of Antibodies 149 9.1.7 Extravascular Tissue Penetration 155 9.1.8 Mechanisms of Antibody Bioactivities 156 9.1.9 Antibody Conjugates 156 9.1.10 Antibodies and Derivatives in Development 158 9.1.11 Summary 159 Section Two 162 9.2 Antibodies and Derivatives Monographs List 162 9.3 Antibodies and Derivatives Monographs 163 10 Hematopoietic Growth and Coagulation Factors 211 Abstract 211 Section One 212 10.1 Molecular Characteristics and Therapeutic Applications 212 10.1.1 Introduction 212 10.1.2 Hematopoietic Growth and Coagulation Factors 212 10.1.3 Therapeutic Use of Hematopoietic Growth Factors (Molineux, Elliott*) 218 10.1.4 Therapeutic Use of Coagulation and Anticoagulation Factors 225 10.1.5 Summary 229 Section Two 231 10.2 Hematopoietic Growth and Coagulation Factors List 231 10.3 Hematopoietic Growth and Coagulation Factors Monographs 231 11 Cytokines and Interferons 251 Abstract 251 Section One 252 11.1 Molecular Characteristics and Therapeutic Applications 252 11.1.1 Introduction 252 11.1.2 Interleukins as Immunotherapeutics 252 11.1.3 Interferon Biology and Cancer Therapy (Tiu, Koon, Borden*) 256 11.1.4 Interferons as Antiviral Therapy 271 11.1.5 Interferons in Multiple Sclerosis 275 11.1.6 Summary 280 Section Two 288 11.2 Cytokines and Interferons Monographs List 288 11.3 Cytokines and Interferons Monographs 288 12 Hormones 307 Abstract 307 Section One 308 12.1 Molecular Characteristics and Therapeutic Applications 308 12.1.1 Introduction 308 12.1.2 Peptide Hormones and Clinical Significance 308 12.1.3 Therapeutic Application of Recombinant and Synthetic Hormones 309 12.1.4 Summary 318 Section Two 320 12.2 Hormones Monographs List 320 12.3 Hormones Monographs 320 13 Enzymes 357 Abstract 357 Section One 358 13.1 Molecular Characteristics and Therapeutic Applications 358 13.1.1 Introduction 358 13.1.2 Enzyme Replacement Therapy 359 13.1.3 Enzymes as Therapeutic Agents 365 13.1.4 Summary and Future Prospects 368 Section Two 370 13.2 Enzymes Monographs List 370 13.3 Enzymes Monographs 370 14 Vaccines (Hu, Ho*) 389 Abstract 389 Section One 390 14.1 Molecular Characteristics and Therapeutic Applications 390 14.1.1 Vaccines and Their Impact on Human Health 390 14.1.2 How Vaccines Work: Interplay among Immune System, Diseases, and Vaccines 393 14.1.3 Traditional Vaccine Approaches 394 14.1.4 Subcellular and Recombinant Subunit Vaccines 395 14.1.5 Vaccine Adjuvants 398 14.1.6 Mode and Route of Vaccine Delivery 400 14.1.7 Future Directions 403 14.1.8 Summary 405 Section Two 409 14.2 Vaccines Monographs List 409 14.3 Vaccines Monographs 409 15 Other Biopharmaceutical Products 417 Abstract 417 15.1 Other Biopharmaceutical Products Monographs List 418 15.2 Other Biopharmaceutical Products Monographs 418 Part III Future Directions 425 16 Advanced Drug Delivery 427 Abstract 427 16.1 Introduction 428 16.2 Drug Therapeutic Index and Clinical Impact 429 16.3 Routes of Therapeutic Protein Administration 430 16.4 Physiological and Mechanistic Approaches 436 16.5 Approaches Using Devices 458 16.6 Molecular Approaches 460 16.7 Summary 465 17 Advances in Personalized Medicine: Pharmacogenetics in Drug Therapy 471 Abstract 471 17.1 Introduction to Interindividual Variation 472 17.2 Historical Perspective on Pharmacogenetics in Drug Safety and Efficacy 473 17.3 Pharmacogenetics in Drug Disposition and Pharmacokinetics 478 17.4 Pharmacogenetics in Drug Effects and Pharmacodynamics 483 17.5 Individualized Gene-Based Medicine: A Mixed Blessing 487 17.6 Current and Future Prospects of Pharmacogenetics 490 17.7 Summary 492 18 Gene and Cell Therapy 495 Abstract 495 18.1 Overview 496 18.2 General Strategies in Gene and Cell Therapy 499 18.3 Gene and Cell Therapy for Select Medical Conditions 501 18.4 Gene Therapy Research, Development, and Clinical Use (Sullivan*) 506 18.5 Stem Cells in Regenerative Medicine and Diagnostics (Kelly*) 509 18.6 Summary 513 19 Integration of Discovery and Development: The Role of Genomics, Proteomics, and Metabolomics 517 Abstract 517 19.1 Overview 518 19.2 Integration of Discovery and Development of Therapeutic Candidates 520 19.3 Genomics: The First Link between Sequences and Drug Targets 521 19.4 Proteomics: From Sequences to Functions 524 19.5 Metabolomics: Metabolic Profile Elucidation 528 19.6 Integrating Genomic, Proteomic, and Metabolomic Tools to Accelerate Drug Development 530 19.7 Summary 532 20 Pharmacoeconomics, Outcome, and Health Technology Assessment Research in Drug Development 535 Abstract 535 20.1 Introduction: Health-Care Decisions and Health Outcomes 536 20.2 Integration of Pharmacoeconomic Outcome Research in Clinical Drug Development 538 20.3 Regional Differences in the Type of Evidence and Value Data Essential for Health-Care and Reimbursement Decisions 541 20.4 Biopharmaceutical Company Strategies 542 20.5 Summary 545 20.6 Acknowledgments 546 21 Future Prospects 547 Abstract 547 21.1 Progress and Benefits in Transforming Proteins and Genes into Biopharmaceuticals 548 21.2 Genomic Information Improves Safety and Production Cost of Biopharmaceuticals 548 21.3 The Business of Biopharmaceuticals and Economic Impacts 549 21.4 Influence of Biopharmaceuticals on Pharmaceutical Research, Development, and the Drug Industry 549 21.5 Public–Private Partnership in Financial and Regulatory Support to Improve Translational Success 550 21.6 Biopharmaceuticals and Public Health Benefits 551 21.7 Public Participation and Influence on Biopharmaceutical Development 551 21.8 Outlook 552 Appendix I. Dosage Form, Pharmacokinetics, and Disposition Data 555 Appendix II. Molecular Characteristics and Therapeutic Use 581 Appendix III. Nomenclature of Biotechnology Products 617 Appendix IV. Other Information 621 Index 633 Color plate section is located between pages 210 and 211.
£999.99
Springer New York Biophysics of RNAProtein Interactions A
Book SynopsisThis book addresses how proteins and RNA interact to carry out biological functions such as protein synthesis, regulation of gene expression, genome defense, liquid phase separation and more.The topics addressed in this volume will appeal to researchers in biophysics, biochemistry and structural biology.Table of ContentsPart 1: RNA Binding Proteins.- Chapter 1: How proteins recognize RNA.- Chapter 2: The interaction between L7Ae family of proteins and RNA kink turns.- Chapter 3: Evolving methods in defining the role of RNA in RNP assembly.- Chapter 4: Single-molecule studies of exonuclease: Following cleavage actions one step at a time.- Chapter 5: Fitting in the age of single-molecule experiments: A guide to maximum-likelihood estimation and its advantages.- Part II: Transcription and Translation.- Chapter 6: A single-molecule view on cellular and viral RNA synthesis.- Chapter 7: Single-Molecule Optical Tweezers Studies of Translation.- Part III: RNA-Guided Protein Machineries.- Chapter 8: Biophysical and biochemical approaches in the analysis of Argonaute-miRNA complexes.- Chapter 9: Biophysics of RNA-guided CRISPR immunity.- Chapter 10: Dynamics of MicroRNA Biogenesis.
£999.99
Lexington Books Science Virtue and the Future of Humanity
Book SynopsisScience, Virtue, and the Future of Humanity addresses each of the key public policy issues of our techno-future from the perspective of deeply informed and philosophically inclined public intellectuals. Among the issues addressed are the detachment of our idea of justice from any credible foundation; Tocqueville's prescience on how a cognitive elite might be the aristocracy to be most feared in our time; robotization and the possibility of being ruled by morally challenged robots; organ markets; the degradation of liberal education by obsessive techno-enthusiasm; biotechnology and biological determinism; the birth dearth and the inevitable erosion of our entitlements; the possibility that our techno-domination is basically an unfolding of the Lockean logic of our foundation; and the future of the free exercise of religion in an aggressively libertarian time. All in all, this book should provoke widespread discussion about the relationship between scientific/technological progress and tTrade ReviewThis is a book about the future—the future of liberty, love, and learning in a scientific age. Ranging from the techno-utopian to the techno-wary, the authors explore the possible shape of the world to come. Can we expect an unbounded, creative future? Or is it true, as Abraham Lincoln said, that ‘This is a world of compensations,’ a world where both human and cosmic nature (not to mention divine justice) set limits and establish relations that have a logic all their own? If even robots need morality, as the AI theorists are beginning to realize, then we really are ‘stuck with virtue.’ This insightful and eloquent collection helps us think more deeply about permanence in the midst of change. -- Diana J. Schaub, Loyola University MarylandTable of ContentsIntroduction. Observations on American Liberty: My Report from the Front, Peter Augustine Lawler Chapter 1. Pensions and Health Care in an Aging Society, James C. Captretta Chapter 2. The Demographic Challenge to Entitlements: A Comment, Criticism, and Caveat, William English Chapter 3. An Earned Humility: Reflections on Professional Obligations to the Living Kidney Donor, Benjamin Hippen Chapter 4. The Science of Politics and the Conquest of Nature, Patrick J. Deneen Chapter 5. The Problem with 'Friendly' Artificial Intelligence, Adam Keiper and Ari N. Schulman Chapter 6. The Case for Enhancing People, Ronald Bailey Chapter 7. Justice without Foundations, Robert P. Kraynak Chapter 8. Blame It on My Genotype (if Not My Criminal Brain): Materialist Metaphysics and the Loss of Human Dignity, J. Daryl Charles Chapter 9. Libertarians vs. Liberal Learning, Peter Augustine Lawler Chapter 10. Machine Morality and Human Responsibility, Charles T. Rubin Chapter 11. Tocqueville on Technology, Benjamin Storey Chapter 12. The Place of Liberal Education in Contemporary Higher Education, Marc D. Guerra
£40.50
Ivan R Dee, Inc Golems Among Us: How a Jewish Legend Can Help Us
Book SynopsisImagine a world where the normal human life span is 150 years, where worn-out vital organs are routinely replaced by spares, where after death you will retain consciousness for eternity in cyberspace, where nanotechnology will enable you to transform a plastic bottle into a filet mignon for you to share with your android spouse. Scientists anticipate such a world within a century. Even now many signs of such biotech "progress" are with us. Accelerating developments in genomics, reproductive biotechnology, bionics, artificial life, genetic engineering, and related fields are compelling us to reexamine our most deeply held beliefs about ourselves and our world. As we do, the figure of Victor Frankenstein and the monster he created looms large: many people today see our predicament through the lens of the Frankenstein story, whose lesson is that humans should not "play God" or tinker with the toolbox of nature, at the risk of tragedy and catastrophe. Yet there is an available alternative both to the Frankenstein vision and to the ebullient enthusiasm of those who anticipate a riskless future. It is the most famous and influential post-biblical Jewish legend, the story of the golem—the creation of an anthropoid by mystical and magical means. Retold and embellished in twentieth-century literature, art, music, drama, film, science, technology, and popular culture, the golem legend has become a metaphor for our times, a resource for applying the wisdom of the past to the perplexities of the present and the challenges of the future. In Golems Among Us, Byron Sherwin briefly traces the fascinating history of the golem legend in Western culture, then shows what lessons it holds for us in navigating a safe journey—philosophically, theologically, ethically, and in public policy—through the minefield of social and biological engineering in which we now stand.Trade ReviewI enjoyed reading Sherwin's book which provided me with new insight into the foundation for a Jewish perspective of biotechnology. Its style of writing is accessible to lay people as well as scientists and scholars in the humanities. A nice critique of different religion-based approaches to bioethical decisions. -- Lee M. Silver, Ph.D., Author of Remaking Eden; Professor of Molecular Biology & Public Affairs, Woodrow Wilson School of Public & InternationalGolems Among Us uses an ancient legend as a catalyst for a fascinating journey through laboratories, clinics, and courtrooms as we confront the impacts of cloning, genetic engineering, and the potential merger of man and machine. Byron Sherwin's compassion, humor, and intellect provide a moral compass to help us navigate through astonishing, promising, and sometimes perilous developments in biotechnology. -- Lori Andrews, Author of Future Perfect: Confronting Decisions About GeneticsTraces the golem story as a prelude to understanding the ways he finds it relevant to a number of modern issues. * Lerner News-Star *Fascinating…thoughtful, absorbing treatment.... Anyone looking to make intelligent decisions about the future would do well to read his work. * The Reporter *Sherwin does a valuable service for the reader in presenting these novel parallels between the golem and problems in biotechnology. * Foreword Reviews *This well–researched book looks at issues with which humanity needs to come to terms, both morally and ethically. * CHOICE *Provocative because it uses a legend about the creation of new beings as means for assessing all human power and potential. -- Martha B. Holstein and Rabbi Peter S. Knobel * Lancet *A fascinating example of applied Jewish philosophy.... We can find…new language for expressing our commtiment to social justice. * Jewish Currents *Enchanting.... A captivating and significant book that is appropriate for the layperson as well as the scientist. * Jewish Book World *Fascinating. * Judaism.Com *An important, unique work. * Naturalgenesis.Net Naturalgenesis.Net Naturalgenesis.Net *
£17.99
States Academic Press Genetic Analyses of Plant and Molecular
Book Synopsis
£112.27
States Academic Press Plant Biotechnology and Molecular Markers
Book Synopsis
£110.81
States Academic Press Materials Design and Clinical Perspectives in
Book Synopsis
£112.27
Callisto Reference Genetically Engineered Organisms: Environmental
Book Synopsis
£118.10
Syrawood Publishing House Biotechnology and Crop Improvement
Book Synopsis
£110.07
Syrawood Publishing House Handbook of Marine Biotechnology
Book Synopsis
£114.44
Anthem Press Structure, Agency and Biotechnology: The Case of
Book SynopsisStructure, Agency and Biotechnology argues for the significance of sociological theory and highlights the insights it can offer to the study of agricultural biotechnology. Cautioning against a simplistic reading of the GM controversy as merely a debate of science versus politics, Aristeidis Panagiotou suggests that the discussion should be embedded in the wider social, political, economic and cultural contexts. Structure, Agency and Biotechnology assesses the 2012 Rothamsted GM wheat trials and proposes that the tension underlying GM technology should be resolved through sustained dialogue, public involvement and broad scientific consensus.Trade Review“This work is both a sophisticated theoretical synthesis and a finely worked case illuminating a topic of profound importance: genetic modification. Panagiotou’s labors bring much-needed clarity to this complex and contested world, moving us well beyond the simple binaries of truth and politics, science and publics. It is recommended to those with an interest in the environment, policy and governance, risk, science and technology, and social theory.” —Steve Matthewman, Associate Professor, Head of Sociology, University of Auckland, New Zealand“This is a fascinating account of the intricacies of one of the most important GMO episodes in the UK. Yet, the greatest achievement of this book lies in its combining a detailed case-study, arguably the hallmark of STS scholarship, with the willingness to engage with contemporary macrosociological theory.” —Eve Seguin, Professor, Department of Political Science & Programme of Postgraduate Studies in Science, Technology and Society, Université du Québec à Montréal, Canada“This is a masterful piece of holistic sociological theory framing the study of a GM controversy. Revisiting structuration theory, Panagiotou offers a very rich discussion of the particularities anchored across different locations. His book presents a critical understanding of science and technology using sociological concepts and methodological bracketing.” —Dominique Vinck, Full Professor, STS Lab, University of Lausanne, SwitzerlandTable of ContentsAcknowledgements; List of Abbreviations; 1. A Holistic Approach to the GM Controversy; 2. Rethinking Science, Technology & Society Relations: Definitions, Boundaries and Underlying Theoretical Problems; 3. Science and Technology Studies: A Critical Overview of the Field; 4. Benton, Mouzelis, Stones: Some Key Advances in Contemporary Sociology; 5. A Holistic Framework for the Study of Agricultural Biotechnology 6. The Rothamsted GM Wheat Trials (I): Technology and Appropriation; 7. The Rothamsted GM Wheat Trials (II): Ideology; 8. What is the GM Controversy? Science, Politics and Prospects; 9. Conclusion; Notes; Bibliography; Index.
£63.00
Union Bridge Books Nanobiotechnology: Basic and Applied Aspects
Book Synopsis‘Nanobiotechnology, basic and applied aspects’ is expected to be of tremendous value to the group of scientists, involved in both basic and applied biology and engineering. The proposed book is a comprehensive compendium of basics of nanoscience and its application in biophysical and biomedical problems. The book describes a brief history and evolution of nanoscience in the first two chapters, which is interesting, and an enriched resource for the undergraduates of nanotechnology and biotechnology. The subsequent chapters gives an in-depth idea of different nanomaterials and their diverse biological applications such as bio-imaging, drug-development, drug-delivery, biosensors etc.. The book could also be immensely interesting for the geologists and naturalists, since it reports the occurrence of nanoparticles, which are derived from biological samples of human, and plants or of edaphic origin. In summary, the book proposed could be a reference or ready-reckoner in the undergraduate/college course-works in nanoscience and nano-biotechnology. It also gives a clear idea of different research directions in the field of nanobiotechnology.Table of ContentsPreface; Book Synopsis; Chapter 1: An Introduction to the Scope of Nanoscience and Nanotechnology — Indrani Roy and Arunava Goswami ; Chapter 2: Natural Nanoparticles — R. L. Brahmachary; Chapter 3: Biological Implications of Metallic Nanoparticles — Shilpi Banerjee, Dhriti Ranjan Saha and Dipankar Chakravorty; Chapter 4: Non-Metallic Nanoparticles and Their Biological Implications — Samrat Roy Choudhury and Arunava Goswami; Chapter 5: Magnetic Nanoparticles — Arindam Pramanik, Panchanan Pramanik; Chapter 6: Biological Implications of Polymer Nanocomposites — Abhijit Bandyopadhyay: Index.
£63.00
Imperial College Press Effective Technology Transfer In Biotechnology:
Book SynopsisBiotechnology is referred to as one of the key enabling technologies of the 21st century. It has the potential to offer solutions for a number of health and resource-based problems the world is facing, such as unmet medical needs and fossil fuel dependency. Considerable effort and investment has been expended in recent years to try and improve the outcomes of technology transfer in order to fulfill this potential.This book presents seventeen best-practice case studies on the topic of effective technology transfer in biotechnology. The selected case studies focus on technology transfer offices, funding models, incubators, education and clusters. Each presents an overview of an initiative that was deployed in Europe with the aim of supporting and stimulating the transfer of biotechnology discoveries and technologies from research laboratories to society. Readers are provided with a critical assessment of each initiative and policy makers, entrepreneurs, cluster managers and research institute managers will find inspiring lessons they can draw on when developing and implementing similar initiatives elsewhere.These cases are the product of research undertaken as part of the ETTBio (Effective Technology Transfer in Biotechnology) project, co-financed by the European Union (ERDF — European Regional Development Fund) and made possible by the INTERREG IVC Programme. ETTBio commenced in January 2012 and concluded in December 2014.
£93.10
Imperial College Press Anaerobic Biotechnology: Environmental Protection
Book SynopsisEnvironmental protection and resource recovery are two crucial issues facing our society in the 21st century. Anaerobic biotechnology has become widely accepted by the wastewater industry as the better alternative to the more conventional but costly aerobic process and tens of thousands of full-scale facilities using this technology have been installed worldwide in the past two decades. Anaerobic Biotechnology is the sequel to the well-received Environmental Anaerobic Technology: Applications and New Developments (2010) and compiles developments over the past five years. This volume contains contributions from 48 renowned experts from across the world, including Gatze Lettinga, laureate of the 2007 Tyler Prize and the 2009 Lee Kuan Yew Water Prize, and Perry McCarty, whose pioneering work laid the foundations for today's anaerobic biotechnology. This book is ideal for engineers and scientists working in the field, as well as decision-makers on energy and environmental policies.Table of ContentsFundamentals: Anaerobic Digestion: About Beauty and Consolation (Willy Verstraete* and Jo De Vrieze); Syntrophy in Anaerobic Digestion (Yoichi Kamagata); Microbial Community Involved in Anaerobic Purified Terephthalic Acid Treatment Process (Takashi Narihiro, Masaru K Nobu, Ran Mei, and Wen-Tso Liu*); State-of-the-Art Anaerobic Ammonium Oxidation (Anammox) Technology (Xiaoming Ji, Yu-Tzu Huang, Qian Wang, Giin Yu Amy Tan, Jih-Gaw Lin, and Po-Heng Lee*); Application of Metagenomics in Environmental Anaerobic Technology (Feng Ju, Herbert H P Fang and Tong Zhang*); Transformations and Impacts of Ammonia and Hydrogen Sulfide in Anaerobic Reactors (Yu-You Li* and Wei Qiao); Modelling Anaerobic Digestion Processes (Damien J Batstone* and Jorge Rodriguez); Applications: Microbial Fuel Cells: From Fundamentals to Wastewater Treatment Applications (Ningshengjie Gao, Keaton Larson Lesnik, Hakan Bermek and Hong Liu*); Development and Applications of Anaerobic Membrane Bioreactor in Japan (Yu-You Li*, Takuro Kobayashi and Shinichiro Wakahara); Anaerobic Fluidized Bed Membrane Bioreactor for the Treatment of Domestic Wastewater (Perry L McCarty, Jeonghwan Kim, Chungheon Shin, Po-Heng Lee and Jaeho Bae*); Development and Application of Anaerobic Technology for the Treatment of Chemical Effluents in Taiwan (Sheng-Shung Cheng*, Teh-Ming Liang, Ryninta Anatrya, and Wen-Tso Liu); Anaerobic Sewage Treatment in Latin America (Carlos A.L. Chernicharo, Jules B Van Lier*, Adalberto Noyola and Thiago B Ribeiro); Applications and Developments of Anaerobic Technology in China (K J Wang*, C P Wang, A J Wang, H Gong, B C Dong, H Xu, L W Deng and C Li); Challenges Towards Sustainability: Development of Anaerobic Digestion of Animal Waste: from Laboratory, Research and Commercial Farms to A Value-Added New Product (Jason C H Shih); Role of Anaerobic Digestion in Increasing the Energy Efficiency and Energy Output of Sugar Cane Distilleries (Adrianus van Haandel* and Jules B van Lier); With AnWT and AnDi-Systems towards a More Sustainable Society (Gatze Lettinga);
£133.20
Anthem Press Structure, Agency and Biotechnology: The Case of
Book SynopsisStructure, Agency and Biotechnology argues for the significance of sociological theory and highlights the insights it can offer to the study of agricultural biotechnology. Cautioning against a simplistic reading of the GM controversy as merely a debate of science versus politics, Aristeidis Panagiotou suggests that the discussion should be embedded in the wider social, political, economic and cultural contexts. Structure, Agency and Biotechnology assesses the 2012 Rothamsted GM wheat trials and proposes that the tension underlying GM technology should be resolved through sustained dialogue, public involvement and broad scientific consensus.Trade Review“This work is both a sophisticated theoretical synthesis and a finely worked case illuminating a topic of profound importance: genetic modification. Panagiotou’s labors bring much-needed clarity to this complex and contested world, moving us well beyond the simple binaries of truth and politics, science and publics. It is recommended to those with an interest in the environment, policy and governance, risk, science and technology, and social theory.” —Steve Matthewman, Associate Professor, Head of Sociology, University of Auckland, New Zealand“This is a fascinating account of the intricacies of one of the most important GMO episodes in the UK. Yet, the greatest achievement of this book lies in its combining a detailed case-study, arguably the hallmark of STS scholarship, with the willingness to engage with contemporary macrosociological theory.” —Eve Seguin, Professor, Department of Political Science & Programme of Postgraduate Studies in Science, Technology and Society, Université du Québec à Montréal, Canada“This is a masterful piece of holistic sociological theory framing the study of a GM controversy. Revisiting structuration theory, Panagiotou offers a very rich discussion of the particularities anchored across different locations. His book presents a critical understanding of science and technology using sociological concepts and methodological bracketing.” —Dominique Vinck, Full Professor, STS Lab, University of Lausanne, SwitzerlandTable of ContentsAcknowledgements; List of Abbreviations; 1. A Holistic Approach to the GM Controversy; 2. Rethinking Science, Technology & Society Relations: Definitions, Boundaries and Underlying Theoretical Problems; 3. Science and Technology Studies: A Critical Overview of the Field; 4. Benton, Mouzelis, Stones: Some Key Advances in Contemporary Sociology; 5. A Holistic Framework for the Study of Agricultural Biotechnology 6. The Rothamsted GM Wheat Trials (I): Technology and Appropriation; 7. The Rothamsted GM Wheat Trials (II): Ideology; 8. What is the GM Controversy? Science, Politics and Prospects; 9. Conclusion; Notes; Bibliography; Index.
£27.79
World Scientific Europe Ltd Engineering Microbial Metabolism For Chemical
Book SynopsisMicrobial metabolism refers to how microbes obtain energy and nutrients needed to live and reproduce. Its uses in chemical synthesis are multiple, and, when engineered, can provide reliable and reproducible reactions for application in industrial or biogeochemical processes.This book provides expert reviews and perspectives on how to engineer microbial metabolism for chemical synthesis. Major metabolic pathways or networks in microbial systems, including glycolysis, citric acid and photosynthesis, are briefly summarized. Following this, the metabolic engineering efforts of extending these pathways and networks for the biosynthesis of various chemicals are reviewed with the emphasis on the biochemical reactions and engineering strategies. The potential of these pathways for further metabolic engineering are also discussed. From graduate to professional level, cellular metabolism and metabolic engineering applications are introduced to the readers gradually and systematically, making it perfect for students, researchers and practitioners of chemistry, biochemistry and metabolic engineering.
£81.70
