Biotechnology Books

Book SynopsisSocial Emergency Medicine incorporates consideration of patients’ social needs and larger structural context into the practice of emergency care and related research. In doing so, the field explores the interplay of social forces and the emergency care system as they influence the well-being of individual patients and the broader community. Social Emergency Medicine recognizes that in many cases typical fixes such as prescriptions and follow-up visits are not enough; the need for housing, a safe neighborhood in which to exercise or socialize, or access to healthy food must be identified and addressed before patients’ health can be restored. While interest in the subject is growing rapidly, the field of Social Emergency Medicine to date has lacked a foundational text – a gap this book seeks to fill. This book includes foundational chapters on the salience of racism, gender and gender identity, immigration, language and literacy, and neighborhood to emergency care. It provides readers with knowledge and resources to assess and assist emergency department patients with social needs including but not limited to housing, food, economic opportunity, and transportation. Core emergency medicine content areas including violence and substance use are covered uniquely through the lens of Social Emergency Medicine. Each chapter provides background and research, implications and recommendations for practice from the bedside to the hospital/healthcare system and beyond, and case studies for teaching. Social Emergency Medicine: Principles and Practice is an essential resource for physicians and physician assistants, residents, medical students, nurses and nurse practitioners, social workers, hospital administrators, and other professionals who recognize that high-quality emergency care extends beyond the ambulance bay.Table of ContentsHistory of Social Emergency MedicinePublic Health, Population Health, and Health DisparitiesRace and RacismGender and Sexual IdentityImmigrationLanguage and LiteracyAccess to CareFrequent Emergency Department Use: A Social Emergency Medicine PerspectiveSubstance Use: A Social Emergency Medicine PerspectiveEducation and EmploymentFinancial InsecurityFood InsecurityHomelessnessHousing Instability and QualityTransportationLegal NeedsNeighborhoods and the Built EnvironmentViolenceFirearm InjuryIncarcerationHuman Trafficking.

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Book SynopsisThis book is the first comprehensive compilation of deliberations on whole genome sequencing of the diploid and tetraploid alfalfa genomes including sequence assembly, gene annotation, and comparative genomics with the model legume genome, functional genomics, and genomics of important agronomic characters. Other chapters describe the genetic diversity and germplasm collections of alfalfa, as well as development of genetic markers and genome-wide association and genomic selection for economical important traits, genome editing, genomics, and breeding targets to address current and future needs. Altogether, the book contains about 300 pages over 16 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers, and scientists in the academia and relevant private companies interested in genetics, breeding, pathology, physiology, molecular genetics and breeding, biotechnology, and structural and functional genomics. The work is also useful to seed and forage industries.Table of Contents

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Book SynopsisThis book serves as the first comprehensive compilation describing the breeding strategies and genetics and genomics of the coconut palm. It describes gene evolution of economically important traits such as oil biosynthesis, aroma and fragrance, disease-resistant genes and small RNAs-mediated gene regulation of coconut. Application of “omics” approaches in palms and the prospects of genome editing technologies in coconut are also discussed. The author list includes pioneers and experts in the field of coconut genomics. The book appeals to postgraduate students, researchers and industry players in the field of plantation crops in general and coconut in particular.Table of ContentsChapter 1. World Economic Importance.- Chapter 2. Botanical Study and Cytology.- Chapter 3. Germplasm Resources: Diversity and Conservation.- Chapter 4. Breeding Strategies.- Chapter 5. Characterization of Genetic Diversity Using Molecular Markers.- Chapter 6. Quantitative Trait Loci (QTL) and Association Mapping for Major Agronomic Traits.- Chapter 7. Palms in an ‘OMICS’ Era.- Chapter 8. Genome Sequencing, Transcriptomics, Proteomics and Metabolomics.- Chapter 9. Mitochondrial and Chloroplast Genomes.- Chapter 10. Endosperm Oil Biosynthesis: A Case Study for Trait Related Gene Evolution in Coconut.- Chapter 11. Aroma and Fragrance: A Case Study for Trait-Related Gene Evolution in Coconut.- Chapter 12. Resistance Gene Candidates (RGCs) in Coconut Palm: A Molecular Platform for the Genetic Improvement of Resistance to Pathogens.- Chapter 13. Epigenetics of Coconut Endosperm Development.- Chapter 14. Genome Editing: Prospects and Challenges.- Chapter 15. Coconut: The Tree Of Life- Endless Possibilities.

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Book SynopsisThis book serves as the first comprehensive compilation describing the breeding strategies and genetics and genomics of the coconut palm. It describes gene evolution of economically important traits such as oil biosynthesis, aroma and fragrance, disease-resistant genes and small RNAs-mediated gene regulation of coconut. Application of “omics” approaches in palms and the prospects of genome editing technologies in coconut are also discussed. The author list includes pioneers and experts in the field of coconut genomics. The book appeals to postgraduate students, researchers and industry players in the field of plantation crops in general and coconut in particular.Table of ContentsChapter 1. World Economic Importance.- Chapter 2. Botanical Study and Cytology.- Chapter 3. Germplasm Resources: Diversity and Conservation.- Chapter 4. Breeding Strategies.- Chapter 5. Characterization of Genetic Diversity Using Molecular Markers.- Chapter 6. Quantitative Trait Loci (QTL) and Association Mapping for Major Agronomic Traits.- Chapter 7. Palms in an ‘OMICS’ Era.- Chapter 8. Genome Sequencing, Transcriptomics, Proteomics and Metabolomics.- Chapter 9. Mitochondrial and Chloroplast Genomes.- Chapter 10. Endosperm Oil Biosynthesis: A Case Study for Trait Related Gene Evolution in Coconut.- Chapter 11. Aroma and Fragrance: A Case Study for Trait-Related Gene Evolution in Coconut.- Chapter 12. Resistance Gene Candidates (RGCs) in Coconut Palm: A Molecular Platform for the Genetic Improvement of Resistance to Pathogens.- Chapter 13. Epigenetics of Coconut Endosperm Development.- Chapter 14. Genome Editing: Prospects and Challenges.- Chapter 15. Coconut: The Tree Of Life- Endless Possibilities.

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Book SynopsisThis book is the first comprehensive compilation of knowledge on teak biology, ecology, clonal forestry, clonal registration, seed biology, and seed orchards. The teak genetic diversity, the sequenced genome, and transcriptomes from different tissues and their implications in modern tree improvement and material selection have been comprehensively discussed. The book also presents a narrative on wood characterization, wood chemistry, modern silviculture, growth and modelling, and economics of this valued tropical species. Altogether, the book contains about 200 pages over 16 chapters authored by globally reputed experts on the relevant field in this tropical tree. This book is useful to students, teachers, and scientists, and wood-based industries are interested in forestry, biology, seed orchards, breeding, genetic diversity, molecular genetics, in vitro culture, wood chemistry, and structural and functional genomics.Table of Contents

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Book SynopsisOver the past decade the world has seen the rise of the fascinating and diverse field currently recognized as nanotechnology. This book covers a broad spectrum of topics within nanotechnology, including synthesis techniques, various innovative characterization techniques, growth mechanisms of nanomaterials, the physics and chemistry of nanomaterials, diverse functionalization methods, and the various applications of nanomaterials in biology, therapeutics, energy, food science, and environmental science. It also discusses applications of nanostructured materials, integrative applications such as nano- and micro-electronic sensor devices, as well as agricultural and environmental remediation applications. The book also includes a discussion of advances in functionalized nanomaterials (0D, 1D, 2D and 3D) and covers the early stages of the development of functionalized nanostructures, considering the future for 2D nanomaterials and 3D objects. Additionally, it includes a chapter on nanomaterial research development that highlights work on the life-cycle analysis of nanostructured materials and toxicity aspects.This book proves useful for researchers and professionals working in the field of nanomaterials and green technology, as well as in the field of nanotechnology. It should be useful to students and specialized researchers in a number of disciplines ranging from biology, chemistry, and materials science to engineering and manufacturing in both academia and industry.Table of ContentsPrefaceChapter 1: Facile Synthesis of Silver Nanocoated Cotton Fabrics from Medicinal Plant Leaf Extract Against Nosocomial InfectionKalitha Parveen P. and Christobher S.PG Department of Zoology, Hajee Karutha Rowther Howdia College of Arts and Science, Uuthamapalayam. Tamil Nadu, IndiaNallamuthu Gounder Mahalingam College, Pollachi, Tamil Nadu, IndiaChapter 2: Biomimetic Synthesis of Silver Nanoparticles from Medicinal Plants and Its Impact on A431 Epidermoid Cancer Cell LinesChristobher S. and Kalitha Parveen P.Department of Zoology, Nallamuthu Gounder Mahalingam College, Pollachi, Tamil Nadu, IndiaHajee Karutha Rowther Howdia College of Arts and Science, Uuthamapalayam. Tamil Nadu, IndiaChapter 3: Role of Nanomaterials in Rheumatoid ArthritisHaripriya Kuchi Bhotla and Arun MeyyazhaganDept of Medicine, University of Perugia, Perugia, ItalyInternational Centre of Neuroscience and Genomic Medicine, 15165 Corunna, SpainChapter 4: Nanoparticles in Food Science and PackagingMohamed Yousuff, Mohamed Imran, Naxar Reehana et al.PG & Research Department of Zoology, Jamal Mohamed College (Autonomous), Tiruchirappalli, Tamil Nadu, IndiaChapter 5: Application of Nanomaterials in Heavy Metal Remediation and Pollution ControlMohamed Ibrahim Salahudeen, Kannan Maharajan and Panneer Selvam MohanaDepartment of Zoology, Jamal Mohamed College, Tiruchirappalli, Tamilnadu, 620020, IndiaChapter 6: Comparison of Biophysical Characters and Insecticidal Potential of Silver Nanoparticles Assisted by Citrus medica, Tagetes lemmonii and Tarenna asiatica ExtractsPeter KleinDepartment of Entomology, Kansas State University, Manhattan, United StatesChapter 7: Review on Recent Advanced Synthetic Methods of NanomaterialsAnnakodi Tamilarasan, Siva Daniel Ajay Samuel, Ravi Visvanand et al.Dept of Biotechnology, Rathnavel Subramaniam College of Arts and Science, Sulur, Coimbatore-641402, Tamil Nadu, IndiaChapter 8: Heterostructured Nanomaterials for Supercapacitor ApplicationsVetha Potheher, K. Prabha and M. RaziaDept of Physics, Anna University, Tiruchirappalli - 620024, Tamil Nadu, IndiaDepartment of Physics, Mother Teresa Women's University, Kodaikanal-624102,Tamil Nadu, IndiaDepartment of Biotechnology, Mother Teresa Women's University, Kodaikanal,Tamil Nadu, IndiaChapter 9: Rare Earthmetals, Transition Metals, Doped Metal Oxide NanoparticlesHaripriya Kuchi Bhotla and Arun MeyyazhaganDept of Medicine, University of Perugia, Perugia, ItalyInternational Centre of Neuroscience and Genomic Medicine, 15165 Corunna, SpainChapter 10: Biogenic Metallic Nanoparticles for Diagnosis and Treatment of Lung CancerUma Maheshwari Nallal V., K. Prabha, I. Vetha Potheher and M. RaziaDepartment of Biotechnology, Mother Teresa Women's University, Kodaikanal, Tamil Nadu, IndiaDepartment of Physics, Mother Teresa Women's University, Kodaikanal, Tamil Nadu, IndiaDepartment of Physics, Anna University, Tiruchirappalli, Tamil Nadu, IndiaChapter 11: Applicability of Nanomaterials in Microbial Fuel Cells as Cathode CatalystsVikash Kumar, Prasanta Pattanayak and Subrata HaitDepartment of Civil and Environmental Engineering, Indian Institute of Technology Patna, Bihar, IndiaDepartment of Polymer Science and Technology, University of Calcutta, Kolkata, West Bengal, IndiaChapter 12: Pollutant Removal from Coffee Industry Wastewater Using Polymer-Based Nano-Adsorbent as a Novel and Promising New Generation AdsorbentKashif Rasool and Dae Sung LeeDepartment of Environmental Engineering, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Republic of KoreaDepartment of Civil and Environmental Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of KoreaHamad Bin Khalifa University, Qatar Research Foundation, QatarChapter 13: A Review on the Application of Biogenic Metal Oxide Nanomaterials in Textile Wastewater TreatmentK.G. Ahila, C. Thamarai Selvi and M. VasanthyDepartment of Biotechnology, Udaya College of Arts and Science, Ammandivillai Kanyakumari, Tamil Nadu, IndiaDepartment of Biotechnology, Mother Teresa Women’s University, Kodaikanal, Tamil Nadu, IndiaDepartment of Environmental Biotechnology, Bhrathidasan University, Trichy, Tamil Nadu IndiaChapter 14: Advanced Two-Dimensional Transition Metal Carbides and Nitrides for Wastewater Treatment ApplicationsAsif Shahzad, Rida Fatima, Kashif Rasool and Dae Sung LeeDepartment of Environmental Engineering, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Republic of KoreaDepartment of Civil and Environmental Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul 04763, Republic of KoreaHamad Bin Khalifa University, Qatar Research Foundation, QatarChapter 15: Carbon Nanomaterials for the Remediation of Industrial EffluentsP.K. Selvi, P. Saranya, N. Vinayagamoorthy and S. SwarnalathaWaste Management Division, Central Pollution Control Board, Parivesh Bhawan East Arjun Nagar, Delhi, IndiaMinistry of Environment, Forest & Climate Change, Indira Paryavaran Bhawan, New Delhi, IndiaDept of Env. Health Engineering, Faculty of Public Health, Sri Ramachandra Institute of Higher Education & Research, Porur, ChennaiEnv. Science and Eng. Division, Central Leather Research Institute, Adyar, Chennai, IndiaChapter 16: Impact of Nanomaterials on Solid Waste ManagementRam K. Ganguly and Susanta K. ChakrabortyDepartment of Zoology, Vidyasagar University, Midnapore-721102, West Bengal, IndiaChapter 17: Agent Nanoencapsulation: A New Approach in Pest ManagementPeter KleinDepartment of Entomology, Kansas State University, Manhattan, United StatesChapter 18: Potential Applications of Nanomaterials in Agronomy: An African InsightHupenyu A. Mupambwa, Adornis D. Nciizah, Patrick Nyambo and Ernest DubeSam Nujoma Marine and Coastal Resources Research Centre, Sam Nujoma Campus, University of Namibia, Henties Bay, NamibiaAgricultural Research Council – Institute for Soil, Climate and Water, Pretoria, South AfricaDepartment of Agronomy, University of Fort Hare, Alice Campus, Alice, South AfricaSchool of Natural Resources Management, Nelson Mandela Metropolitan University, George Campus, South AfricaChapter 19: Application of Emerging Nanomaterials in Animal Origin Products and Packaging from IndonesiaAndi FebrisiantosaResearch Unit for Natural Product Technology (BPTBA)—Indonesian Institute of Sciences (LIPI), Yogyakarta 55861, IndonesiaBibliographyIndex

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Book SynopsisThis book provides updated and all-inclusive data and evidences for Moringa botany, cytogenetical analysis, genetic resources and diversity, classical genetics, traditional breeding, tissue culture, genetic transformation, whole-genome sequencing, comparative genomics and elucidation on applications of functional genomics, nanotechnology, bioinformatics, processing and value addition besides providing perspectives of medicinal and therapeutic properties of Moringa. Moringa gained global attention in the recent past owing to its unique blend of affordable nutraceutical and pharmaceutical compounds in all parts of the plants. Scientific literatures supporting its health benefits besides the studies on its utility in various fields are scattered on several reports. This book is written by renowned global subject experts by compiling and narrating it in a sober style.Table of Contents

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Book SynopsisThis book describes past and present advances in engineering materials for neural applications, with special emphasis on their usefulness for traumatic brain and spinal cord injuries. The book presents major physio-pathological features of traumatic injuries at the brain and spinal cord as examples of diseases hampering the central nervous tissue. By incorporating knowledge from the perspective of experts with diverse backgrounds, this book gives insight into the understanding of these multifaceted pathologies and the materials science approaches that aim to cure them. The interdisciplinary nature of this book makes it a perfect candidate for the interest of a broad audience, from clinicians working on neural diseases to scientists whose work focuses on the nervous tissue (neuroscientists) and/or materials science. Undergraduate and PhD students can also benefit from the knowledge and discussion included in this book.Table of Contents

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Book SynopsisThis book is the first volume in a three-volume set on Solid Waste Engineering and Management. It provides an introduction to the topic, and focuses on legislation, transportation, transfer station, characterization, mechanical volume reduction, measurement, combustion, incineration, composting, landfilling, and systems planning as it pertains to solid waste management. The three volumes comprehensively discuss various contemporary issues associated with solid waste pollution management, impacts on the environment and vulnerable human populations, and solutions to these problems. Table of ContentsChapter 1-Introduction to solid waste management.- Chapter 2-Legislation for solid waste management.- Chapter 3-Waste transportation and transfer station.- Chapter 4-Characterization and measurement of solid waste.- Chapter 5-Mechanical Volume Reduction.- Chapter 6-Combustion and Incineration.- Chapter 7- Composting processes.- Chapter 8-Sanitary landfill operation and management.- Chapter 9-Solid Waste Systems Planning.- Chapter 10-Practices of solid waste disposal.- Chapter 11-Landfilling and the Environmental Impacts.

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Book SynopsisWith the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.Table of ContentsFOREWORDProf. G. VeerabhadramPREFACEChapter 1: Introduction to active smart nanomaterials for biomedical applicationsJin-Chul KimKangwon National University, Chuncheon, South Korea Chapter 2: Cancer cell sensing and therapy using affinity tag-conjugated gold nanoparticlesAlle MadhusudhanKangwon National University, Chuncheon, South Korea Chapter 3: Gold nanoparticles enlighten the future of cancer theranosticsJianfeng GuoSchool of Pharmaceutical Sciences, Jilin University, 1266, Fujin Road, Changchun 130021, ChinaChapter 4: Recent advances in hydrogels smart drug delivery systems Sharif AhmadDepartment of Pharmacology, All India Institute of Medical Sciences, India Chapter 5: Carbon-based nanomaterials for biomedical applicationsKai YangState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, China Chapter 6: A new era of cancer treatment: carbon nanotubes as drug delivery toolsAlexander M SeifalianCentre for Nanotechnology and Regenerative Medicine, University, College London, London, UK Chapter 7: pH- and ion-sensitive materials for control drug delivery Takayuki YoshidaDrug Delivery, Pharmaceutical Research and Technology Labs, Astellas Pharma, Inc., 180 Ozumi, Yaizu, Shizuoka 425-0072, JapanChapter 8: Thermo-responsive polymers and their application as smart biomaterialsYukiko T. MatsunagaCenter for International Research on Integrative Biomedical Systems (CIBiS), The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, JapanChapter 9: Redox-responsive polymers and their application in drug delivery systemsJohn F. QuinnARC Centre of Excellence in Convergent Bio-Nano Science & Technology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Melbourne, Victoria 3052, AustraliaChapter 10: Recent strategies to explore the biomedical applications of nanocelluloseDinesh KumarKangwon National University, Chuncheon, South Korea Chapter 11: Tissue engineering using cellulose nanofibrils as Scaffold MaterialAndrew E. PellingSymbioticA, School of Human Sciences, University of Western Australia, Perth, WA, AustraliaChapter 12: Use of solid lipid nanoparticles to improve the oral bioavailability of poor soluble drugsDeepti PanditaDepartment of Pharmaceutics, Jan Nayak Ch. Devi Lal Memorial College of Pharmacy, Sirsa 125055, Haryana, IndiaChapter 13: Applications of dendrimers in drug delivery systemsE. BustosCentro de Investigacion y Desarrollo Tecnol ´ ogico en Electroqu ´ ´ımica S.C., Parque Tecnologico Quer ´ etaro s/n, Sanfandila, 76703 Pedro Escobedo, QRO, MexicoChapter 14: Liposomes for drug delivery: progress and problemsJin-Chul KimKangwon national University, Chuncheon, South KoreaChapter 15: Cubosome nanoparticles for enhanced delivery of anticancer drugJana B. NiederDepartment of Nanophotonics, Ultrafast Bio- and Nanophotonics Group, INL - International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga s/n, 4715-330, Braga, PortugalChapter 16: Layer‐by‐Layer assemblies for cancer diagnosis and treatment UMR CNRS/INPG 5628 (LMGP), 3 parvis Louis Néel, 38016 Grenoble, FranceChapter 17: Polymeric micelles for drug deliveryAfsanesh Lavasanifar University of Albert, Edmonton, Alberta T6G2N8, CanadaChapter 18: Role of plant-based materials/gums in developing drug delivery systems B. Sashidhar Rao Department of Biochemistry, Osmania University, Hyderabad, IndiaChapter 19: Ethosomes: A novel tool for drug delivery through the skinAmarachinta Padmanabha RaoChapter 20: Niosomes as nanoparticular drug carriers: fundamentals and recent applicationsNoufel SamedChapter 21: Graphene oxide nanosheets used in photothermal therapyHongjie Dai Department of Chemistry, Stanford University, Stanford, California 94305, United States Chapter 22: Metal doped carbon dots used in bio-imaging and cancer therapyJoydeep DasSchool of Chemistry, Shoolini University of Biotechnology and Management Sciences, Bajhol, PO Sultanpur, Solan, HP, 173229, IndiaBIBLIOGRAPHYGLOSSARYINDEX

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Book SynopsisThis open access textbook introduces the emerging field of Development Engineering and its constituent theories, methods, and applications. It is both a teaching text for students and a resource for researchers and practitioners engaged in the design and scaling of technologies for low-resource communities. The scope is broad, ranging from the development of mobile applications for low-literacy users to hardware and software solutions for providing electricity and water in remote settings. It is also highly interdisciplinary, drawing on methods and theory from the social sciences as well as engineering and the natural sciences.The opening section reviews the history of “technology-for-development” research, and presents a framework that formalizes this body of work and begins its transformation into an academic discipline. It identifies common challenges in development and explains the book’s iterative approach of “innovation, implementation, evaluation, adaptation.” Each of the next six thematic sections focuses on a different sector: energy and environment; market performance; education and labor; water, sanitation and health; digital governance; and connectivity. These thematic sections contain case studies from landmark research that directly integrates engineering innovation with technically rigorous methods from the social sciences. Each case study describes the design, evaluation, and/or scaling of a technology in the field and follows a single form, with common elements and discussion questions, to create continuity and pedagogical consistency. Together, they highlight successful solutions to development challenges, while also analyzing the rarely discussed failures. The book concludes by reiterating the core principles of development engineering illustrated in the case studies, highlighting common challenges that engineers and scientists will face in designing technology interventions that sustainably accelerate economic development.Development Engineering provides, for the first time, a coherent intellectual framework for attacking the challenges of poverty and global climate change through the design of better technologies. It offers the rigorous discipline needed to channel the energy of a new generation of scientists and engineers toward advancing social justice and improved living conditions in low-resource communities around the world.Table of ContentsPart I: A New Discipline: Development Engineering.-Chapter 1: The Role Of Technology In Development.- Chapter 2: The Development Engineering Framework: Innovate, Evaluate, Scale.-Chapter 3: Asking the Right Questions.-Part II: Water, Sanitation and Health.-Chapter 4: Advances In Water and Health Technologies.-Chapter 5: Case Study: Electrochemical Arsenic Remediation, India (Innovation).-Chapter 6: Case Study: Information For Intermittent Water Supply, India (Evaluation).-Chapter 7: Case Study: Mobile Phone Diagnostic Microscopy, Vietnam/Cameroon (Innovation, Scale).-Part III: Governance.- Chapter 8: Technologies for Governance And Accountability.-Chapter 9: Case Study: Sensors For Aid Accountability, Rwanda (Evaluation, Scale).-Chapter 10: Case Study: High Resolution Development Indicators, Afghanistan (Evaluation, Scale).-Chapter 11: Case Study: Monitoring For Elections And Public Service Delivery, Kenya (Evaluation, Scale).-Part IV: Energy and Resources.-Chapter 12: Advances in Energy & Environmental Technologies.-Chapter 13: Case Study: Economic Impacts Of Rural Electrification, Kenya (Evaluation, Scale).-Chapter 14: Case Study: Cool Joule: Flexible Energy Loads, Nicaragua (Innovation, Evaluation).-Chapter 15: Case Study: Cookstove Monitoring and Use In East Africa (Innovation, Evaluation).-Part V: Information.-Chapter 16: Information and Communications Technology For Development.-Chapter 17: Case Study: Community Cellular Networks, Philippines (Innovation, Evaluation).-Chapter 18: Case Study: ICT Solutions To Bring Telemedicine To Rural India (Innovation).-Chapter 19: Case Study: Platforms For Development Data (ODK/Mezuri) (Innovation, Scale).-PART VI: Markets (Incorporates Agriculture).-Chapter 20: Technologies To Improve Market Performance.-Chapter 21: Case Study: Ag Market Information Platforms, India (Innovation, Evaluation, Scale).-Chapter 22: Case Study: Agricultural Trading Platforms, Uganda (Innovation, Evaluation).-Chapter 23: Case Study: Inventory And Supply Chain Tracking, Sri Lanka (Evaluation).-PART VII: Human Capital (Incorporates Labor).-Chapter 24: Increasing the Productivity of Human Capital.-Chapter 25: Case Study: Electronic Job Search Platforms, India (Evaluation, Scale).-Chapter 26: Case Study: Customized E-Learning Innovations, India (Evaluation).-Chapter 27: Case Study: TBD (Evaluation).-PART VIII: Conclusion.-Chapter 28: Promising Directions in Development Engineering.

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Book SynopsisIn this edited volume, scientists from different disciplines discuss modern biotechnological processes and a knowledge-based bioeconomy. The authors base their arguments on ecological, economic, legal, social and ethical aspects. Moreover, they explore the opportunities, risks, and challenges of bioeconomic concepts and biotechnologies in many subject areas. The chapters consider land use, nature and environment, nutrition, technology and governance, energy, economy, law and regulation, as well as ethics. A special focus should be on new technologies and how they can be used, without compromising the ambitious goal of creating a more sustainable, but also fair world. To do justice to this broad array of topics, the editors frame all topics in overarching introductions and close the volume with final conclusions. Thereby this volume offers data and critical thoughts for any member of a Bioeconomy – be it from academia, the industry or public regulation.Table of ContentsPart I: Introduction and Overview1. Scientific Introduction [working title] (Ulrich Schurr) 2. Ethical Introduction [working title] (Dirk Lanzerath) Part II: Energy and Land Use 3. “Global Shifting Agriculture” and Bioeconomy: Challenges for the Sustainable Use of Global Land Resources (Jan Börner) 4. Sustainable Resources – From Plants to Products (Ralf Pude, C. Wever, T. Kraska) Part III: Nutrition and Food Ethics 5. Food as a Moral Problem (Birgit Beck) 6. Bioeconomy and Food Security: Moral Conflicts due to Climate Change and Population Growth (Patrick Hohlwegler) 7. Acceptance of Insects and In-Vitro-Meat as Sustainable Meat Substitute in Germany – In Search of Decisive Food-Psychological Influences (Florian Fiebelkorn, Jacqueline Dupont, Patrik Lammers) Part IV: Technology and Governance 8. Characteristics of Innovation in Bioeconomy (Max Mittenzwei) 9. Spatial Implications of the Leitmotif Shift from Biotechnology to Bioeconomy (Leonard Prochaska, Daniel Schiller) 10. Problem Structures of the Bioenergy Policy in the Power and Heating Sectors (Katrin Beer) 11. The Bioeconomy Transformation in the German Rheinische Revier – Stakeholders and Discourses in Media Coverage (Sandra Venghaus, Sophia Dieken, Maria Belka) Part V: Regulation and Economics 12. Bioeconomy and Genome Editing – Germany and the Netherlands in Comparison (Robin Siebert, Christian Herzig, Marc Birringer) 13. Monitoring and Measuring Bioeconomy (Maximilian Kardung) 14. Resource Sufficiency in a Sustainable Bioeconomy: A Predator-Prey Perspective (Lioudmila Chatalova) 15. Biotechnology and Law [working title] (Julian Kinderlerer) 16. Economics of Bioeconomy [working title] (Justus Wesseler) Part VI: Normativity and Ethics 17. Bioeconomy and Ethics (Bart Gremmen) 18. Bioeconomy: An Environmental-Ethical Perspective (Marion Stahl) 19. Conditions of an Ethically Responsible and Sustainable Bioeconomy Based on the Responsibility Ethics of Hans Jonas (Jana Schoop) 20. Bioeconomy as a Normative Concept of Resilience – Challenges and Chances (Sebastian Lenze) Part VII: Conclusions and Outlook 21. Bioeconomy: Challenges and Conflicts from an Interdisciplinary Perspective [working title] (Mandy Stake) 22. Bioeconomy: Challenges and Conflicts from a Philosophical, Socio-Political and Ethical Perspective [working title] (Christina Pinsdorf)

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Book SynopsisThis book is the first comprehensive compilation of the most up-to-date research in the genomics, transcriptomics, and breeding of pine species across Europe, North America, and Australia. With chapters on the state of the reference genomes, transposon function, genome-wide diversity, functional genomics, genomics of disease resistance, genomics of abiotic stress, and genomic selection, this book is a must-read for scientists, breeders, and students of plant genomics. The book contains 12 chapters over 300 pages authored by a group of world-renowned scientists in the field of pine genomics. Pines (Pinus) are the world’s most economically important forest tree species. The recent genome sequencing of several important pine species has paved the way for understanding their complex biology and helps future management and breeding efforts.Table of Contents

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Book SynopsisThis book examines issues relating to postsecondary transition from high school to college or competitive vocational settings for Autistic adolescents and young adults. It details the intervention and consultation services essential to prepare students for postsecondary life. The volume addresses the academic, social, self-regulation, and self-sufficiency skills that adolescents and young adults must develop to ensure a successful transition from high school to college and workplace. It focuses on the role of school psychologists in supporting Autistic students as they enter adulthood but is also relevant across numerous disciplines. Key topics addressed include: Using cognitive and neuropsychological assessment results to inform consultation about college entrance and vocational activities. Evaluating and strengthening academic skills for older Autistic adolescents who plan to enter college or workforce. Helping Autistic students increase their use of social, coping, and behavioral skills. Strengthening Autistic students’ use of self-management and self-sufficiency skills needed to independently perform required tasks in college and the workplace. Selecting an appropriate college and accessing available supports that match student needs. Assisting Autistic students and their families in accessing available services and developing skills that improve employment outcomes. Postsecondary Transition for College- or Career-Bound Autistic Students is a must-have resource for researchers, professors, and graduate students as well as clinicians and other professionals in clinical child and school psychology, special education, social work, developmental psychology, behavioral therapy/rehabilitation, child and adolescent psychiatry, and all interrelated disciplines.Table of ContentsChapter 1. Understanding Adolescents with High-Functioning ASD.- Chapter 2. Barriers to Successful Transition.- Chapter 3. Cognitive and Neuropsychological Assessment of Adolescents with High-Functioning ASD.- Chapter 4. Academic Assessment and Intervention for Adolescents with High-Functioning ASD.- Chapter 5. Social, Emotional, and Behavioral Assessment and School-Based Intervention for Adolescents with High Functioning ASD.- Chapter 6. Self-Management and Self-Sufficiency.- Chapter 7. College Students with ASD.- Chapter 8. Considering College Alternatives.- Chapter 9. Transition-Related Legal and Ethical Considerations.- Chapter 10. Transition Preparation: Providing Building-Level Supports in Middle and High Schools.- Chapter 11. Obtaining Appropriate Services in College.- Chapter 12. Obtaining Appropriate Services for the Workplace.- Chapter 13. Considerations for School Psychology University Faculty.

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Book SynopsisThis classroom-tested textbook will assist dental students with their academic research activities and help them to be competitive in today’s fast-growing research environment. It is designed as a core text for dental school classes such as Research Methodology and Scientific and Technical Writing, as well as Responsible Conduct of Research (RCR) training, but will also be a valuable resource for students and researchers in related fields, such as the medical sciences and biomedical engineering. The authors start the book by explaining key concepts and common approaches in dental research, both in basic science and clinical dentistry. They then familiarize readers with evidence-based research in dentistry and how to write a systematic review, explain the process of designing and presenting a proposal, discuss reporting results both in scientific and clinical research, and cover ethics in research, highlighting the significance of adherence to ethics both in animal as well as human studies.Table of ContentsIntroduction - Types of Dental Research.- Research Design.- Systematic Review and Evidence-Based Research in Dentistry.- Writing a Research Proposal.- The Scientific and Clinical Research Report.- Reference Management for Researchers.- Ethics in Research.

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Book SynopsisThis volume focuses on the biomedical aspects of inorganic polyphosphates, a family of unique bio-inorganic polymers.In recent years, great advances have been made in understanding the development, metabolism, and physiological role of inorganic polyphosphates. These energy-rich polymers, which consist of long chains of phosphate units, are evolutionary old molecules. The acidocalcisomes, conserved organelles from bacteria to humans, as well as the mitochondria play a central role in polyphosphate production and storage. Polyphosphates have been assigned multiple functions, some of which are closely related to medically important processes, such as blood coagulation and fibrinolysis, energy metabolism, cell cycle regulation, apoptosis, chaperon function, microvascularization, stress response, neurodegeneration and aging. The development of bioinspired polyphosphate particles, in combination with suitable hydrogel-forming polymers enabled the development of new strategies in regenerative medicine, in particular for hard and soft tissue repair, but also in drug delivery and antimicrobial defense. This book not only highlights the basic research in this area, but also discusses possible applications. Therefore, it appeals to scientists working in cell biology, biochemistry, and biomedicine and practicioners alike.Table of Contents1. Mitochondrial polyP production Prof. Dr. Andrey Y. Abramov, University College London, London, UKa.abramov@ucl.ac.uk 2. Polyphosphate in thrombosis and inflammation Prof. Dr. James H. Morrissey and Dr. Stephanie Smith, University of Michigan Medical School, Ann Arbor MI, USAjim@tf7.org or jhmorris@umich.edu3. Polyphosphate in mitochondrial energy metabolism and pathologyProf. Dr. Evgeny Pavlov, NYU College of Dentistry, New York NY, USAep37@nyu.edu4. Polyphosphate in plasma and human pathologies Prof. Dr. Felix Ruiz, Facultad de Medicina, Universidad de Cádiz, Cádiz, Spainfelix.ruiz@uca.es5. PolyP in neurodegeneration and agingProf. Dr. Maria E. Solesio, Rutgers University, Camden NJ, USAm.solesio@rutgers.edu6. Effects of polyphosphate on function of leukocytesDr. Patrick Suess, University of Michigan Medical School, Ann Arbor MI, USApsuess@med.umich.edu7. PolyP and Vtc complexProf. Dr. Andreas Mayer, University of Lausanne, Epalinges, Switzerlandandreas.mayer@unil.ch8. PolyP in antiviral protectionProf. Dr. Dr. h.c. Werner E. G. Müller, Prof. Dr. Xiaohong Wang, Prof. Dr. Dr. Heinz C. Schröder, University Medical Center of Johannes Gutenberg University Mainzwmueller@uni-mainz.de9. Polyphosphate in biomimetic implant materialsProf. Dr. Dr. Heinz C. Schröder, Prof. Dr. Xiaohong Wang, Prof. Dr. Dr. h.c. Werner E. G. Müller, University Medical Center of Johannes Gutenberg University Mainzwmueller@uni-mainz.de

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Book SynopsisThis 2nd book provides fundamental concepts and recent applications of biotechnological methods, such as genetic selection, breeding methods and genetic engineering tools. Biotechnology has remarkably improved the productivity of livestock by increasing the reproduction efficiency and decreasing the generation time. The chapters detail the mechanisms of methods for animal reproduction and breeding methods. This book focus on the impact of minerals, steroids metabolic stress, nutritional stress and anti-nutritional factors on the livestock reproduction.Table of ContentsPreface1. Impact of sex steroids on the stress response and welfare in female farm ruminantsAline Freitas-de-Melo and Rodolfo Ungerfeld2. Insights from proteomics in kidney disease diagnosis and various in vitro and in vivo experimental modelsVikram Patial, Garima Dadhich, and Rajiv Kumar3. Generation of gene edited pigsS. Navarro-Serna, C. Piñeiro-Silva, R Romar, J. Parrington, and J Gadea4. Dietary anti-nutritional factors and their roles in livestock nutritionSalma H. Abu Hafsa, Ayman A. Hassan, Mona M.MY. Elghandour, Alberto Barbabosa-Pliego, Miguel Mellado, and Abdelfattah Z.M. Salem5. Genetic engineering tools and techniques in livestock productionRanjitha H.B., Madhu Ramesh, Subhasmita Behera, Dhanesh ValiyaValappil, Suresh H. Basagoudanavar, and Anjum Sherasiya6. Mineral Ions in Regulation of Hypothalamic-Pituitary-Ovarian Axis Mustafa Hassan Jan, Harpreet Singh, and Shikha Kapil7. Molecular Insights of Compromised Female Reproduction in Ruminants under Metabolic and Nutritional StressS. Nandi, S. K Tripathi, PSP Gupta, and S. MondalIndex

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Book SynopsisAntibiotics, the backbone of modern clinical-medicine, are facing serious challenges from emerging antimicrobial-resistance (AMR), a complicated phenomenon expanding in bacterial species, from nosocomial to community origins, where microbes are no longer sensitive to a range of commonly used antibiotics. AMR has exploded in recent years and is posing a serious threat to human health and survival. This necessitates novel and effective ways of diagnosis, drug-delivery, and treatment; nanotechnology and advanced nanomaterials are hailed as a potent solution in containing AMR.The main thrust of this volume is to explain the most current research on the central theme of potential use of nano-approaches for diagnosis, detection, drug-delivery and as antimicrobial agents against drug-resistant pathogenic microbes. This book provides an integrated blend of basic and advanced information for students, scholars, scientists and practitioners, interested or already engaged in research in these areas. We have brought together leading international authors to present and highlight various aspects of nanotechnology in combating AMR in WHO-prioritized microbes. Topics range from advances in nanomaterial synthesis, characterization, functionalization and improvisation, as well as applications in sensing, diagnosis of AMR, and their therapeutic and drug-delivery potential against MDR and XDR microbial phenotypes.Table of Contents1 The History of Antibiotics Illumes the Future of Antimicrobial Peptides Administered Through Nano-Systems2 Current approaches and prospects of nanomaterials in rapid diagnosis of antimicrobial resistance3 Nanomaterials-mediated delivery of antimicrobial agents ‘The Nanocarriers’4 Nanoparticle functionalization: Approaches and applications5 Nano-adjuvants as effective next-generation antimicrobial agents6 Limiting antibiotic-resistant bacteria using multifunctional nanomaterials7 Microbial resistance mechanisms and potential of metal-organic framework in mitigation thereof8 Silver-based Nano-Formulations for Treating Antibiotic-Resistant Microbial Strains9 Gold Nanoparticles: A Lethal Nanoweapon against Multidrug Resistant Bacteria10 Antimicrobial Potentials of Zinc and Iron Oxide Nanoparticles11 Carbon Nanostructures for Fighting Antimicrobial Resistant Bacteria12 Nano-formulations against Multidrug Resistant Members of ESKAPE pathogens

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Book SynopsisMolecular farming is a biotechnological approach that includes the genetic adjustment of agricultural products to create proteins and chemicals for profitable and pharmaceutical purposes. Plant molecular farming describes the manufacture of recombinant proteins and other biologically active product in plants. This approach depends on a genetic transformation of plants that can be accomplished by the methods of stable gene transfer, such as gene transfer to nuclei and chloroplasts, and unstable transfer methods like viral vectors. The requirement for recombinant proteins in terms of quality, quantity, and diversity is increasing exponentially This demand is traditionally met by recombinant protein construction technologies and the engineering of orthodox expression systems based on bacteria or mammalian cell cultures. However, majority of developing countries cannot afford the high costs of medicine derived from such existing methods. Hence, we need to produce not only the new drugs but also the cheaper versions of those already present in the market. Plant molecular farming is considered as a cost-effective technology that has grown and advanced tremendously over the past two decades. This book summarizes the advances and challenges of plant molecular farming for all those who are working on or have an interest in this rapidly emerging area of research.Table of Contents​Chapter. 1. Molecular Farming in Plants: Introduction and ApplicationsChapter. 2. Tools and Techniques Used in Plant Molecular FarmingChapter. 3. Production of plant natural products in heterologous microbial speciesChapter. 4. Sustainable Manufacturing of Vaccines, Antibodies, and other PharmaceuticalsChapter. 5. Limitations, Biosafety, ethics, regulatory issues in molecular farming in plantsChapter. 6. Conclusion and Perspectives

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Book SynopsisAccess to food with enough calories and nutrients is a fundamental right of every human. The global population has exceeded 7.8 billion and is expected to pass 10 billion by 2055. Such rapid population increase presents a great challenge for food supply. More grain production is needed to provide basic calories for humans. Thus, it is crucial to produce 60-110% more food to fill the gap between food production and the demand of future generations.Meanwhile food nutritional values are of increasing interest to accommodate industrialized modern lives. The instability of food production caused by global climate change presents another great challenge. The global warming rate has become more rapid in recent decades, with more frequent extreme climate change including higher temperatures, drought, and floods. Our world faces various unprecedented scenarios such as rising temperatures, which causes melting glaciers and the resulting various biotic and abiotic stresses, ultimately leading to food scarcity. In these circumstances it is of utmost importance to examine the genetic basis and extensive utilization of germplasm to develop “climate resilient cultivars” through the application of plant breeding and biotechnological tools. Future crops must adapt to these new and unpredictable environments. Crop varieties resistant to biotic and abiotic stresses are also needed as plant disease, insects, drought, high- and low-temperature stresses are expected to be impacted by climate change. Thus, we need a food production system that can simultaneously satisfy societal demands and long-term development.Since the Green Revolution in the 1960s, farming has been heavily dependent on high input of nitrogen and pesticides. This leads to environmental pollution which is not sustainable in the long run. Therefore, a new breeding scheme is urgently needed to enable sustainable agriculture; including new strategies to develop varieties and crops that have high yield potential, high yield stability, and superior grain quality and nutrition while also using less consumption of water, fertilizer, and chemicals in light of environmental protection. While we face these challenges, we also have great opportunities, especially with flourishing developments in omics technologies. High-quality reference genomes are becoming available for a larger number of species, with some species having more than one reference genome. The genome-wide re-sequencing of diverse varieties enables the identification of core- and pan-genomes. An integration of omics data will enable a rapid and high-throughput identification of many genes simultaneously for a relevant trait. This will change our current research paradigm fundamentally from single gene analysis to pathway or network analysis. This will also expand our understanding of crop domestication and improvement. In addition, with the knowledge gained from omics data, in combination with new technologies like targeted gene editing, we can breed new varieties and crops for sustainable agriculture.Table of ContentsChapter. 1. The utilization of speed breeding and genome editing to achieve zero hungerChapter. 2. Multiomics approach for crop improvement under climate changeChapter. 3. The intervention of multi-omics approaches for developing abiotic stress resistance in cotton crops under climate changeChapter. 4. Big data revolution and machine learning to solve genetic mysteries in crop breedingChapter. 5. Applications of multi-omics approaches for food and nutritional securityChapter. 6. Applications of high throughput phenotypic phenomicsChapter. 7. Basil (Ocimum basilicum L.) : Botany, Genetic resource, Cultivation, Conservation, and Stress factorsChapter. 8. Multi-Omics Approaches for Breeding in Medicinal PlantsChapter. 9. Applications of some nanoparticles and responses of medicinal and aromatic plants under stress conditionsChapter. 10. Sustainable agriculture through technological innovationsChapter. 11. Sustainable Rice Production under Biotic and Abiotic Stress ChallengesChapter. 12. Emerging Techniques to Develop Biotic Stress Resistance in Fruits and VegetablesChapter. 13. Genome editing in crops to control insect pestsChapter. 14. CRISPR revolution in gene editing, targeting plant stress tolerance and physiologyChapter. 15. Genomics for Abiotic Stress Resistance in LegumesChapter. 16. Genetic and molecular factors modulating phosphorous use efficiency in plantsChapter. 17. Recent Trends in Genome Editing Technologies for Agricultural Crops ImprovementChapter. 18. Recent trends and applications of omics based knowledge to end global food hungerChapter. 19. Nutritional enhancement in horticultural crops by CRISPR/ Cas9: status and future prospectsChapter. 20. Physiological interventions of antioxidants in crop plants under multiple abiotic stressesChapter. 21. Proteomics and its scope to study salt stress tolerance in quinoaChapter. 22. Sustainable Cotton Production in Punjab: Failure and its Mitigating StrategiesChapter. 23. Biosafety and biosecurity in genetically modified crops

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Book Synopsis The dependency on animal biotechnology in livestock industries has been increased in the recent past. The livestock production research has witnessed remarkable developments on biotechnological methods to produce the elite animal breeds. The global animal food requirement has been steadily increasing, and animal production needs to be increased as per the global needs. This book covers various aspects of animal biotechnology such as, reproductive biotechnologies in sheep and goats, oogenesis and folliculogenesis and ovarian disorders. This book focusses the discussion on proteomics and metabolomics, and separate chapters were dedicated to discuss these topics. The proteomics studies of animal viruses were discussed in this book, and this would be helpful to understand animal viral pathogenesis. The applications of metabolomics in livestock were discussed with focus on data analysis, identification of unknown compounds. The purpose of this book is to provide the recent research trends, and convert all this information to usable guide to professionals, researchers and students who are working the research area of animal biotechnology. Table of Contents

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Book SynopsisDieses Buch befasst sich mit den Herausforderungen und Möglichkeiten von Open-Source- und kollaborativen Designansätzen und -strategien im biomedizinischen Bereich. Es bietet eine umfassende Reihe von bewährten Verfahren und Methoden, damit diese sicheren, innovativen und zertifizierbaren biomedizinischen Geräte die Patienten erreichen und erfolgreiche Lösungen für Probleme im Gesundheitswesen bieten. Die Kapitel sind so gegliedert, dass sie den gesamten Lebenszyklus von Open-Source-Medizintechnologien verfolgen. Die bereitgestellten Informationen sind äußerst praxisorientiert, da sie sich auf reale Studienfälle stützen, bei denen sich die Zusammenarbeit zwischen medizinischen Fachkräften, Ingenieuren und Technikern, Patienten und Patientenverbänden, politischen Entscheidungsträgern, Regulierungsbehörden und Bürgern als vorteilhaft erwiesen hat. Das Buch wird auch durch eine Online-Infrastruktur, UBORA, unterstützt, über die Open-Source-Medizinprodukte gemeinsam entwickelt und geteilt werden können, um die Medizintechnik zu demokratisieren und eine zugängliche biomedizintechnische Ausbildung zu fördern. Table of ContentsVorwort: Das UBORA-Projekt I. GRUNDLAGEN 1. Die medizinische Industrie: Gegenwärtige Situation, globale Gesundheitsprobleme und Ausblick 2. Allgemeine Überlegungen zur Entwicklung von Open-Source-Medizinprodukten 3. Systematische Bewertung des Bedarfs und Tragfähigkeitsanalysen II. ENTWURFSMETHODEN FÜR OPEN-SOURCE-MEDIZINPRODUKTE 4. Kreativitätsförderung: Kollaborative Designumgebungen und offene Innovation 5. Sicherheitsgerichtete Entwurfsmethoden für Open-Source-Medizinprodukte 6. Entwurf und Simulation von Open-Source-Medizinprodukten III. HERSTELLUNGSMETHODEN FÜR OPEN-SOURCE-MEDIZINPRODUKTE 7. Prototyping von Open-Source-Medizinprodukten 8. Herstellung von personalisierten Open-Source-Medizinprodukten 9. Massenproduktion von Open-Source-Medizinprodukten IV. MIT OPEN-SOURCE-MEDIZINPRODUKTEN WIRKLICH ETWAS BEWIRKEN 10. Open-Source-Zulassung und -Zertifizierung von Medizinprodukten 11. Vermarktung von Open-Source-Medizinprodukten: Management von Qualität und Lieferkette 12. Fragen im Zusammenhang mit der langfristigen Nachhaltigkeit von Open-Source-Medizinprodukten REFERENZEN ANHÄNGE

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Book SynopsisDieses Lehrbuch führt den Leser auf zugängliche und ansprechende Weise in die Grundlagen der Proteinexpression und -entwicklung ein. Verschiedene Fallstudien veranschaulichen jeden Schritt von der ersten Sequenzsuche in Online-Datenbanken über Plasmiddesign und molekulare Klonierungstechniken bis hin zur Proteinreinigung und -charakterisierung. Darüber hinaus erhält der Leser praktische Tipps für eine erfolgreiche Karriere als Proteiningenieur. Da das Protein-Engineering eine grundlegende Technik in fast allen molekularbiologischen Labors ist, richtet sich das Buch an fortgeschrittene Studenten und Doktoranden, die in der Molekularbiologie, Biotechnologie und verwandten wissenschaftlichen Bereichen arbeiten.Table of ContentsTeil I: Kapitel 1: Eine kurze Geschichte des Protein-EngineeringKapitel 2: Von der DNA zum funktionellen Protein - eine AuffrischungKapitel 3: Grundlegende Labor- und RechentechnikenTeil II:Kapitel 4: Strategien des Protein-EngineeringKapitel 5: Computergestützte Werkzeuge für das Protein-EngineeringKapitel 6: GenisolierungKapitel 7: Rationaler Entwurf Kapitel 8: Gezielte EvolutionKapitel 9: ProteinmodifikationTeil III:Kapitel 10: Berufsperspektiven eines ProteiningenieursKapitel 11: Gespräche mit Proteiningenieuren

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Book SynopsisThis volume “Cell Engineerring 11 - Biopharmaceutical Manufacturing: Progress, Trends and Challenges” is a source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation.The book comprises contributions of experts from academia and industry active in the field of cell culture development for the production of recombinant proteins, cell therapy and gene therapy, with consideration of Digital Twin´s and facility design. The knowledge and expertise of the authors cover disciplines like cell biology, engineering, biotechnology and biomedical sciences. Inevitably, some omissions will occur in the test, but the authors have sought to avoid duplications by extensive cross-referencing to chapters in other volumes of this series and elsewhere. We hope the volume provides a useful compendium of techniques for scientists in industrial and research laboratories active in this field.Table of ContentsPart I: Manufacturing of Recombinant Therapeutic Proteins.- Chapter 1. Single-Use Systems in Biopharmaceutical Manufacture: State of the Art and Recent Trends (Jossen et al.).- Chapter 2. Recent Developments in Bioprocess Monitoring Systems (Rahmatnejad et al.).- Chapter 3. Advances in Characterization of Industrial Bioreactors for Cell Culture Process (Fitschen et al.).- Chapter 4. Continuous Bioprocessing for Upstream Process - Perfusion Process (Chotteau et al.).- Chapter 5. Continuous Bioprocessing for Downstream (Gerstweiler).- Chapter 6. Towards Digital Twin for Biopharmaceutical Processes: Concept and Progress (Ding et al.).- Chapter 7. Integrated Process and Supply Chain Design and Optimization (Triantafyllou et al.).- Chapter 8. Production of Complex Proteins in Plants – From Farming to Manufacturing (Nausch et al.).- Chapter 9. Manufacturing of Recombinant Proteins Using Quality by Design (QbD) Methodology: Current Trend and Challenges (Shin and Landauer).- Chapter 10. Biopharma 4.0 for Biologics Manufacturing Under Pandemic Constraints (Schmidt et al.).- Chapter 11. Biopharma 4.0: Digital Technologies Driving Smart Manufacturing (Nargund et al.).- Part II: Manufacturing Aspects of Cell and Gene Therapy .- Chapter 12. Essential Aspects of Mesenchymal Stem Cell Manufacturing (Fleischhammer et al.).- Chapter 13. Towards a Continuous Production of Human Mesenchymal Stromal Cells in a Chemically Defined Medium: Opportunities and Challenges for a Robust and Scalable Expansion Process (Tasto and Salzig).- Chapter 14. Biomanufacturing Aspects of Gene Therapy (Warnock).- Chapter 15. Manufacturing and Quality of Advanced Therapeutics: Cellular Therapies, CAR-T and Gene Therapies (van den Bos et al.).

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Book SynopsisBiomechanical Homeostasis.- Mechano-Biology.- Growth and Remodeling of Coronary Vasculature.- Growth and Remodeling: Coronary Veins and Therapeutic Implications.- Growth and Remodeling: Network Flow Analysis.- Scaling Laws of Growth and Remodeling.- Design Rules for Treatment of Coronary Bifurcation Lesions.- Computational Fluid Dynamics of Coronary Artery Disease.- Hemodynamic Design of Coronary Graft.

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Book SynopsisThis reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.Table of ContentsSources.- Primary cells.- Chondrocytes.- Muscle cells.- ß-cells.- Schwann cells.- Cell lines for test systems.- Immortalized primary cells.- STEM.- Bone marrow derived.- Placenta derived cells.- Amnion.- in toto.- Placenta / Chorion.- Cord/Wharton cells.- Amniotic fluid cells.- Adipose derived cells.- Isolation enzymatic.- SVF.- Isolation non-enzymatic.- SVF.- ASC.- Perivascular / Angiogenic cells origin.- Multiple Sources.- Blood.- Olfactory mucosa.- Tendon.- iPS, ES or Transdifferentiation.- ESC.- Many sources and routes to iPS.- Needs for clinical application.- Tools for mechanistic studies.- HaploBank.- Autologous or Allogeneic.- Preconditioning.- Sorting.- Biophysical.- Chemical.- Transfection.- Aggregation.- Sheets.- Microaggregates.- Two level approach.- Modulation.- Growth factors.- miRNA.- Epigenetic approaches.- Biophysical.- Two level approach.- "Student-Teacher".- Coculture.- "Student-School".- Environmental Cues.- Application Routes.- Systemic.- Local.- Endogenous catching.- SDF-1-CXCR4 axis.- Cell Tracking.- Action.- Cell differentiation.- Cell-cell contact.- Secretome.- Learning from embryogenesis / evolution.- Basics of amphibian self regeneration.

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Book SynopsisSurface-Functionalized Ceramics Focused coverage of making and using functional ceramic materials for a wide variety of scientific and technical applications Surface-Functionalized Ceramics provides a comprehensive overview of surface functionalization approaches for ceramic materials, including alumina, zirconia, titania, and silica, and their uses as sensors, chemical, and biological probes, chromatographic supports for (bio)molecule purification and analysis, and adsorbents for toxic substances and pollutants. Overall, the text provides a broad picture of the enormous possibilities offered by surface functionalization and addresses the current challenges regarding surface analysis, characterization, and stability. As a well-rounded resource, the text points out opportunities of surface-functionalized ceramics, their issues such as achieving surface stability and complex analysis, and how to counter them. Edited by two experts in the field of advanced materials surfaces, Surface-Functionalized Ceramics covers topics such as: Processing methods for advanced ceramics, surface modification of ceramic materials, and methods for electrokinetic surface characteristics Surface imaging and chemical surface analysis using atomic force microscopy Surface chemical analysis and ceramic-enhanced analytics Biological and living matter-surface interactions including protein adsorption mechanisms as well as bacteria behavior in terms of biofilm formation and prevention for antibacterial applications Mesoporous silica and organosilica biosensors for water quality and environmental monitoring, plus ceramic-based adsorbents in bioproduct recovery and purification For professionals, researchers, and academics in the fields of materials science, biotechnology, biotechnological industry, environmental sciences, and ceramics industry, Surface-Functionalized Ceramics is a one-stop reference on the subject that provides different approaches to obtain surfaces of ceramic materials that perform desired functions.Table of ContentsIntroduction to Ceramic Materials Processing Methods for Advanced Ceramics Surface Modification of Ceramic Materials Surface Imaging and Structure Methods for Chemical Surface Analysis: Atomic Force Microscopy Surface Chemical Analysis of Ceramics and Ceramic-Enhanced Analytics Methods for Electrokinetic Surface Characteristics Functionalized Surfaces and Interactions with Biomolecules Bacteria-Surface Interactions: Biofilm Formation and Prevention Carbon Nanomaterials for Antibacterial Applications Mesoporous Silica and Organosilica Biosensors for Water Quality and Environmental Monitoring Ceramic-Based Adsorbents in Bioproduct Recovery and Purification

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Book SynopsisGives a comprehensive description on the biological model, basic physical models, fabrication/characterization of bioinspired materials and their functions.Table of ContentsPreface 1 Introduction of bio-inspired Structure Surfaces 1.1 Bionics is boosting advanced materials 1.2 Bio-inspired structural surfaces(BSS) 1.2.1 Definition and classification of BSS 1.2.2 Typical prototypes with structural surfaces 1.3 Characterization techniques and analysis methods of BSS 1.3.1 Preparation of biological prototypes 1.3.2 Characterization techniques of BSS 1.3.3 Analysis methods of BSS 1.4 Modeling and simulation methods of assistant bionic design 1.4.1 Translight method 1.4.2 FDTD method 1.4.3 Other modeling related methods 1.5 Design principles and fabrication methods of BSS 1.5.1 Design principles of BSS 1.5.2 Fabrication methods of BSS 1.5.3 Synthetic design and fabrication strategies of BSS 2 Bio-inspired antireflective (AR) surfaces 2.1 Definition and classification of AR materials 2.1.1 Antireflective coatings (ARCs) 2.1.2 Antireflective structures (ARSs) 2.1.3 Comprehensive comparison between ARCs and ARSs 2.2 Light trapping AR surfaces inspired by butterfly wings 2.2.1 AR mechanism of original butterfly wings 2.2.2 Fabrication of structural butterfly-inspired AR surfaces 2.2.3 Characterizations of butterfly-inspired AR surfaces 2.2.4 AR performance of butterfly-inspired structural surfaces 2.2.5 AR mechanism of butterfly-inspired structural surfaces 2.3 Transparent AR surfaces inspired by cicada wings 2.3.1 AR mechanism of original cicada wings 2.3.2 Fabrication of cicada-inspired AR surfaces 2.3.3 Characterizations of cicada-inspired AR surfaces 2.3.4 AR performance of cicada-inspired structural surfaces 2.3.5 AR mechanism of cicada-inspired structural surfaces 3 Bio-inspired antifogging (AF) surfaces 3.1 Wettability-induced AF theories 3.1.1 Smooth surfaces: Young model and the static contact angle 3.1.2 Wenzel model 3.1.3 Cassie-Baxter model 3.2 Dynamic wettability: Contact angle hysteresis and sliding angles 3.3 Definition and classification of AF surfaces 3.3.1 Superhydrophilic AF surfaces 3.3.2 Superhydrophobic AF surfaces 3.4 AF surfaces inspired by butterfly wings 3.4.1 Characterizations and analysis of original AF butterfly wings 3.4.2 Fabrication of butterfly-inspired AF surfaces 3.4.3 Characterizations and analysis of biomimetic AF monolayer film (BMF) 3.4.4 AF performance of butterfly-inspired MHPSs surfaces 3.4.5 AF mechanism of butterfly-inspired MHPSs surfaces 3.5 Structural AF surfaces inspired by mayfly compound eyes 3.5.1 AF mechanism of original compound eyes 3.5.2 Fabrication of superhydrophobic antifogging surfaces (SSASs) 3.5.3 Wettability and composition analysis of the SSASs 3.5.4 AF performance of the SSASs 3.5.5 AF mechanism of the SSASs 4 Structure color surfaces inspired by butterfly wings 4.1 Definition of structure color surfaces 4.2 Structure color surfaces on butterfly wings 4.2.1 Papilio palinurus butterfly wings 4.2.2 Morpho butterfly wings 4.3 Fabrication of the butterfly-inspired structure color materials 4.3.1 Sol-gel process 4.3.2 Soft lithography 4.3.3 Layer deposition techniques 4.3.4 Electron beam lithography 4.4 Applications of the structure color materials 5 Bio-inspired oil-water separation materials 5.1 Definition and classification of oil-water separation materials 5.1.1 Superhydrophobic-oleophilic materials 5.1.2 Underwater superoleophobic materials 5.1.3 Superhydrophilic-superoleophobic materials 5.1.4 Smart materials with switchable wettability 5.2 Oil-water separation materials inspired by butterfly wings 5.2.1 Characterizations of original butterfly wings 5.2.2 Design principle for butterfly-based oil-water separation materials 5.2.3 Fabrication of butterfly-inspired oil-water separation materials 5.2.4 Characterizations of butterfly-inspired oil-water separation materials 5.2.5 Performance of butterfly-inspired oil-water separation materials 5.3 Oil-water separation materials inspired by fish scales 5.3.1 Underwater superoleophobic performance on fish scales 5.3.2 Biomimetic design strategy for oil-water separation materials 5.3.3 Fabrication of fish-inspired oil-water separation materials 5.3.4 Characterizations of fish-inspired oil-water separation materials 5.3.5 Oil-water separation evaluation of fish-inspired structural materials 6 Bio-inspired responsive surfaces toward multiple organic vapors 6.1 Responsive performance of Morpho butterfly wings 6.1.1 Vapor responsive platform for responsive measurements 6.1.2 Responsive mechanism of butterfly wings toward incident angles 6.1.3 3D visible parameterized models of butterfly feature structures 6.2 Fabrication of butterfly-inspired structural responsive surfaces 6.3 Characterizations of butterfly-inspired structural responsive surfaces 6.3.1 Morphology characterizations 6.3.2 Composition characterizations 6.4 Responsive performance of BSS towards multiple organic vapors 6.4.1 Reflective spectra of BSS toward organic vapors 6.4.2 Responsive evaluation based on introduced sensitive corner 6.4.3 Responsive mechanism of the BSS 7 Prospect and Outlook Index

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Book SynopsisMit dem Standardwerk gewinnen Leser einen umfassenden Einblick in die diagnostische und therapeutische Medizintechnik, in das Life Science Engineering und wichtige angrenzende Gebiete. Die 5. Auflage wurde u. a. um Themen wie sportorthopädische Medizintechnik, Blutpräparate und Textilien für Implantate ergänzt. Die Zertifizierung für Medizintechnik, Kosmetik, Pharma und Nahrungsmittel nimmt erstmals umfassenden Raum ein und berücksichtigt damit die verschiedenen nationalen Regelungen, die für das Inverkehrbringen der jeweiligen Produkte gelten.Trade ReviewAus den Rezensionen zur 4. Auflage: "Dieses etablierte Lehrbuch über bioverträgliche Implantate bietet einen grundlegenden und umfassenden Einstieg in das Gebiet Medizintechnik. Es wendet sich vor allem an Studenten, Wissenschaftler und Ingenieure in Werkstoffkunde und biomedizinischer Technik, aber auch an Mediziner und Produktionstechniker …" (in: upgrade, 2007/2008, Issue 4, S. 49) "... Das Buch soll weiterhin ein modernes Nachschlage- und Unterrichtswerk eines besonders attraktiven Wachstumsgebietes bleiben." (in: medizin & technik, 2008, Issue 4, S. 75) "Das ... Fachbuch … wurde umfassend ergänzt und aktualisiert. Den Herausgebern … ist es sehr gut gelungen, Themen aus … der Medizintechnik und … Life Science anschaulich … praxisnah darzustellen. Hierbei werden Themen aus der Medizin mit technischen Inhalten anschaulich verknüpft und komplexe Sachverhalte gut verständlich dargestellt. … Das Fachbuch dient ... als Nachschlagewerk und fundierte lnformationsquelle ... Als Lehrhuch ermöglicht es den Studierenden einen schnellen Einstieg in komplexe medizinische und technische Sachverhalte. Das vorliegende Werk ist ein gelungenes Beispiel für Interdisziplinarität ..." (http://www.kunststoffe.de/ku/overview_bookshop.asp?task=4&isbn=978-3-540-74924-0) "... Das 800 Seiten starke Buch verschafft dem Leser eine solide Übersicht über die Medizintechnik. Seien es gesetzliche Komponenten wie das Medizinproduktegesetz, eine Übersicht mit Studien- und Ausbildungseinrichtungen der Medizintechnik oder eben der umfangreiche ‘spezielle Teil’ des Bandes, der Aufbau und Funktionsweise wichtigster medizinischer Geräte erläutert … Ärztliche Kunst und Technik gehen … eine Überzeugende Verbindung ein." (http://buchkatalog.de) "Die Medizintechnik hat sich mit ihrem hohen Innovationsgrad … zu einem äußerst vielschichtigen Gebiet entwickelt. Das spiegelt sich sehr anschaulich in der … 4. Auflage des Lehrbuchs ‘Medizintechnik‘ … Das Standardwerk … deckt nicht nur alle vertrauten Bereiche von Biokompatibilität bis zahnmedizinische Werkstoffe ab. In die erweiterte Auflage wurden … zahlreiche neue Kapitel aufgenommen … Ergänzt werden die technologischen Kapitel durch ökonomisch relevante Gesichtspunkte … Das Buch soll … nicht nur ein nützliches Nachschlagewerk für Lernende, Forscher und Entwickler sein, sondern auch jungen Firmengründern Anregung und Hilfestellung bieten." (Gewichtiger Überblick, in: meditec INTERNATIONAL, 2008, Issue 2, S. 31) "Das Standardwerk ... soll Praktikern aus Medizin und Technik als Nachschlagewerk und lnformationsquelle dienen. Die Grundlinien und Intentionen des Fachbuchs sind unverändert geblieben: Disziplinäre Betrachtung, lnterdisziplinarität durch Kommunikation, klinische und wirtschaftliche Relevanz." (in: medizin & technik, 2008, Issue 6, S. 95)Table of ContentsImpulse – Teil 1.- Editorial.- Grundlagen der Medizintechnik.- Biokompatibilität.- Biofunktionalität.- Sterilisation.- Biologische Grundlagen.- Zellen.- Blut.- Gewebe.- Immunsystem.- Werkstoffe in der Medizintechnik.- Biokompatible Metalle.- Biokompatible Polymere.- Biokompatible Keramische Werkstoffe.- Faserverbundwerkstoffe.- Textilverstärkte Kunststoffbauteile in funktionsintegrierender Leichtbauweise.- Radioaktive Biomaterialien.- Tissue Engineering / Stammzell Engineering.- Grundlagen des Tissue Engineering.- Mikroreaktortechnik für Tissue Engineering.- Electrospinning.- Tissue Engineering in der Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie.- Zellträgersysteme.- Stammzellen.- Blutpräparate und therapeutische Anwendung (Hämotherapie).- Magnetoseed – Vasculäres Tissue Engineering.- Prozesstechnologien für medizintechnische Entwicklungen.- Kunststoffverarbeitung für die Medizintechnik.- Spritzgießen.- Sonderverfahren des Spritzgießens.- Mikrospritzgießen.- Extrusion & Compoundierung.- Mikrospritzgießanlage ?-Ject mit Linearantrieb.- Extrusion von ein- und mehrlumigen Katheterschläuchen aus thermoplastischen Kunststoffen.- Reinraumtechnik für die Medizintechnik.- Cell 3D: Kunststoffschäume für dreidimensionale Zellkultivierung.- Systemlieferant und OEM Hersteller für die Medizintechnik und Pharmabranche.- Atmosphärisches Plasma in der Medizintechnik.- Dünne Beschichtungen auf Biomaterialien.- PVD-Beschichtungstechnologie.- Polymer-/Medikamentenbeschichtung von oberflächenstrukturierten metallischen Werkstoffen.- Titanisierung von Implantatoberflächen.- Mikrostrukturtechnik und Biomaterialien.- Oberflächenstrukturierung metallischer Werkstoffe, z. B. für stents.- Sticktechnologie für medizinische Textilien und Tissue Engineering.- Medizinische Textilien.- Wundversorgung.- Die Fadeninjektion.- Diagnostische Medizintechnik und minimalinvasive Verfahren.- Magnetresonanztomographie.- Medizinische Bildgebung.- Theragnostik: Diagnostische Systeme mit integrierter Therapie.- Endoskopie, minimal-invasive Chirurgie und navigierte Systeme.- Endoskopie, minimal invasive chirurgische und navigierte Verfahren in der Urologie.- Single-Use Instrumente in der endoskopischen Gastroenterologie.- Bildanalyse in Medizin und Biologie.- Blutdruckmessung.- Therapeutische Medizintechnik.- Stenting und technische Stentumgebung.- Kontrollierte therapeutische Systeme (Controlled drug delivery systems).- Chirurgisches Nahtmaterial und Nahttechniken.- Elektrische Phänomene des Körpers und ihre Detektion.- Technische Systeme für den Herzersatz und die Herzunterstützung.- Die Herz-Lungen-Maschine.- Herzklappenchirurgie.- Innovative Aortenklappenimplantation.- Minimalinvasive endovaskuläre Stent-Therapie bei Erkrankungen in der thorakalen Aorta.- Prothetischer Ersatz der thorakalen Aorta.- Chirurgie angeborener Herzfehler.- Endoskopische Entnahme der Bypassgefäße.- Homograft Bank in der Herzchirurgie.- Kalzifizierung biologischer Herzklappenprothesen.- Plastische und rekonstruktive Mund-, Kiefer- und Gesichtschirurgie – Technische Aspekte.- Grundlagen der Nieren- und Leberdialyse.- Degradable Implantate: Entwicklungsbeispiele.- Biokeramik für Anwendungen in der Orthopädie.- Hüftgelenks-Endoprothesen.- Aktuelle Entwicklungen – Orthopädische Implantate.- Entwicklung und aktueller Stand der Hüftendoprothetik.- Medizintechnik in der Tumororthopädie.- Implantate für den Bandscheibenersatz (Stand 1993).- Exoprothetik.- Neue Techniken in der Neurorehabilitation.- Sportorthopädische Medizintechnik.- Innovation durch Paradigmenwechsel – zur Bone Welding® Technologie.- Biomaterialien für die Knochenregeneration.- Einführung in die Hörgerätetechnik.- Funktionsersatz des Innenohres.- Transplantate und Implantate im Mittelohrbereich – Teil 1 (Stand 2002).- Implantate im Mittelohrbereich – Teil 2 (Ergänzungen 2007).- Implantate in der Augenheilkunde.- Implantate und Verfahren in der Augenheilkunde.- Dentalwerkstoffe und Dentalimplantate – Teil 1.- Dentalwerkstoffe und Dentalimplantate – Teil 2.- Biokompatible Implantate und Neuentwicklungen in der Gynäkologie.- Maschinengestütztes Operieren, Mechatronik und Robotik.- Apparativ-technische Ausstattung im Rettungs- und Notarztdienst.- Qualitätsmanagement in der Medizintechnik.- Qualitätsmanagementsysteme – Teil 1.- Qualitätsmanagement – Teil 2.- Haftung in der Medizintechnik.- TÜV – Zertifizierungen in der Life Science Branche.- Impulse – Teil 2.- Ökokompatible Werkstoffe.- Erweiterung der Biokompatibilität auf Ökosysteme und Werkstoffe.- Story I: Impella – Eine Erfolgsgeschichte mit Achterbahnfahrt.- Story II: Kommerzialisierung innovativer Technologien – das Beispiel der WoodWelding SA.- Strategische Planung in der Medizintechnik.- Venture Kapital und Life Science.- Patentierung und Patentlage.- Technologie-Management in der Medizintechnik.- KTI Initiative Medtech.- Rückwärtsintegration – Zu den Verhältnissen Gymnasium, Hochschule und Arbeitswelt.- Life-Science Praktika am Lehrstuhl für Medizintechnik der TU München.- Lithotripsie.

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