Biochemical engineering Books
Cambridge University Press Separation of Molecules Macromolecules and Particles
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£71.24
John Wiley & Sons Inc The Engineering of Human Joint Replacements
Book SynopsisSince the major pioneering of joint replacement surgery more than fifty years ago, much research and progress has been made in the field of arthroplasty with new insights into better materials, types of cement and bone-cell compatible coatings, and a better understanding of the causes of implant failure.Table of ContentsPreface xi 1 Introduction 1 References 5 2 Basic Anatomy 7 2.1 Terminology 7 2.2 Human Skeleton 8 2.3 Joints 10 2.4 Cartilage 10 2.5 Protein and Collagen 11 2.6 Human Bone 14 References 22 3 Anatomy of Joints 25 3.1 Shoulder 25 3.2 Elbow 29 3.3 Wrist 34 3.4 Finger 38 3.5 Hip 38 3.6 Knee 43 3.7 Ankle 49 3.8 Foot 52 3.9 Toe 52 3.10 Degradation of Joints 54 References 56 4 Methods of Inspection for Joint Replacements 59 4.1 Introduction 59 4.2 Gait Analysis 60 4.3 X-ray 61 4.4 Tomography and Computed Tomography (CT) 64 4.5 Radionuclide Scanning 66 4.6 Ultrasonography 66 4.7 Magnetic Resonance Imaging (MRI) 67 References 69 5 Materials in Human Joint Replacement 71 5.1 Introduction 71 5.2 Alloy Metals 71 5.3 Ceramics 79 5.4 Polymers 83 5.5 Joint Replacement Materials in Service 91 5.6 Nanomaterials 95 References 98 6 Methods of Manufacture of Joint Replacements 103 6.1 Introduction 103 6.2 Surface Finish 104 6.3 Tolerance 106 6.4 Wear and Friction 106 6.5 Machining 106 6.6 Forging 112 6.7 Casting 114 6.8 Manufacture of Polymer Parts 119 6.9 Surface Treatment 121 6.10 Surface Finishing of Implants 125 6.11 Manufacture of Joint Replacements 127 References 128 7 Computer-Aided Engineering in Joint Replacements 131 7.1 Introduction 131 7.2 Reverse Engineering 132 7.3 Solid Modelling 133 7.4 Finite Element Analysis (FEA) 137 7.5 Rapid Prototyping (RP) in Joint Replacement Manufacture 141 7.6 Computer-Aided Manufacture 145 7.7 Navigation 150 7.8 Robotics 153 References 162 8 Joint Replacement 167 8.1 Introduction 167 8.2 Shoulder 171 8.3 Elbow 175 8.4 Wrist 178 8.5 Fingers 180 8.6 Hip 183 8.7 Knee 191 8.8 Ankle 200 8.9 Foot and Toe 203 References 206 Index
£87.35
John Wiley and Sons Ltd Pharmaceutical Emulsions
Book SynopsisPharmaceutical Emulsions: A Drug Developer's Toolbag covers all the key aspects of pharmaceutical emulsions, starting from the fundamental scientific basics, to the pharmaceutical forms and the chemical tests for its application.Table of ContentsMathematical symbols (with normal units) xi Acronyms and abbreviations xiii Preface xv Acknowledgements xvii About the companion website xix I Product considerations: medicinal formulations 1 1 Historical perspective 5 1.1 Landmarks 5 1.2 Significant discoveries 7 1.3 Difficulties 8 1.4 Traditional uses 10 1.5 Product regulation 13 2 What is an emulsion? 15 2.1 States of matter 24 2.2 Summary thermodynamics 34 2.3 Interfacial tension and wetting 36 2.4 Shear and size reduction 46 2.5 Raw materials 47 3 Stability, metastability and instability 49 3.1 Stokes’ law 51 3.2 Derjaguin–Landau–Verwey–Overbeek (DLVO) theory 52 3.3 Interfacial rheology 56 4 Manufacture 63 4.1 Premixing 63 4.2 High-shear mixers and size reduction 64 4.3 Multiple and microemulsions 65 4.4 Hot melt (steriles) 65 4.5 Filling 66 II Forms, uses and applications: biopharmaceutics 67 5 Creams and ointments 69 5.1 Nutraceuticals and cosmeceuticals 71 5.2 Medicinals 71 6 Pastes and bases 77 6.1 Emolliency 77 6.2 Suppositories 78 6.3 Pessaries 79 7 IV colloids 81 7.1 Needle free 86 7.2 Ocular therapy 87 7.3 Cancer 88 7.4 Antimicrobials 90 7.5 Temperature-sensitive matrices and release forms 93 7.6 Targeted endosomal use 94 7.7 Solid lipid nanoparticles 95 7.8 Diagnostic emulsions 98 8 Transdermal patches: semisolids 99 8.1 Hormones 104 8.2 Analgesia 104 8.3 Anaesthesia 104 8.4 Nicotine 105 8.5 Inserts: vaginal rings 105 9 Gels 107 9.1 Micro- and nanogels 107 9.2 Semisolids 107 10 Implants 109 10.1 Plastics and glasses 109 10.2 Thermoresponsive materials 110 11 De novo science, sustainable novel products and platform applications 111 11.1 Tablets 113 11.2 Metered-dose inhalers 113 11.3 Blood substitutes 114 III Tests: chemistry to control the quality, efficacy and fitness for purpose of a product 117 12 Physicochemical properties 119 12.1 Thermal evaluation (differential scanning calorimetry) and lipid polymorphs 124 12.2 Drug form, log P and Lipinski rules 129 12.3 Skin and epithelial models 133 12.4 Drug delivery routes 134 13 Sizing and microscopy 137 13.1 ζ -potential 137 13.2 Hydrodynamic diameter 139 14 Rheology, texture, consistency and spreadability 141 14.1 Bulk properties 141 14.2 Solid-state and nanorheological properties 144 14.3 Interfacial properties 144 15 Quality control, process analytical technology and accelerated testing 149 15.1 Preformulation, high-throughput screening 150 15.2 Industrial concerns 151 15.3 Rancimat and other methods 152 Questions 155 Guide for readers 155 Specimen 'test' questions 155 Answers 168 References 173 Index 181
£102.08
McGraw-Hill Education Connect Access Card for Heat and Mass Transfer
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£121.22
McGraw-Hill Education Loose Leaf for Heat and Mass Transfer
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£174.60
McGraw-Hill Education Loose Leaf for Introduction to Chemical Processes
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£180.13
ISA Analytical Instrumentation
Book SynopsisThis treatment of process analytical technology, by a distinguished array of experts, chronicles over 50 years of process analyzer development - from its origin in the research laboratory at Ludwigshafen in the late 1930's to a dynamic worldwide technology in the early 1990s. Offering some theory and a lot of real-world, hands-on experience, this book is designed for field analyzer technicians, newly graduated engineers-in-training, and knowledgeable manufacturers application personnel. Included are drawings of sample systems that work and comments on ones that don't work. In addition, justifications and organization guidelines on process analyzer systems are presented. The volume describes analyzers from the systems side looking at implementation issues including justification, purchasing, training and validation. Specific analyzer types and the fundamentals of application for a variety of situations are explored. Contents: Introduction to This Technology Typical Analyzer Application Justifications Interfacing Analyzers With Systems Specification and Purchasing of Analyzers Calibration Considerations Training Aspects SPC/SQC for Analyzers Personnel and Organizational Issues Validation of Process Analyzers Sample Conditioning Systems Component Specific Analyzers Electrochemical Analyzers Compositional Analyzers Spectroscopic Analyzers Physical Property.
£161.60
Arcadia Publishing Inc. The Meriden Flint Glass Company An Abundance of
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£18.69
ISTE Ltd and John Wiley & Sons Inc Process Engineering and Industrial Management
Book SynopsisProcess Engineering, the science and art of transforming raw materials and energy into a vast array of commercial materials, was conceived at the end of the 19th Century. Its history in the role of the Process Industries has been quite honorable, and techniques and products have contributed to improve health, welfare and quality of life. Today, industrial enterprises, which are still a major source of wealth, have to deal with new challenges in a global world. They need to reconsider their strategy taking into account environmental constraints, social requirements, profit, competition, and resource depletion. “Systems thinking” is a prerequisite from process development at the lab level to good project management. New manufacturing concepts have to be considered, taking into account LCA, supply chain management, recycling, plant flexibility, continuous development, process intensification and innovation. This book combines experience from academia and industry in the field of industrialization, i.e. in all processes involved in the conversion of research into successful operations. Enterprises are facing major challenges in a world of fierce competition and globalization. Process engineering techniques provide Process Industries with the necessary tools to cope with these issues. The chapters of this book give a new approach to the management of technology, projects and manufacturing. Contents Part 1: The Company as of Today 1. The Industrial Company: its Purpose, History, Context, and its Tomorrow?, Jean-Pierre Dal Pont. 2. The Two Modes of Operation of the Company – Operational and Entrepreneurial, Jean-Pierre Dal Pont. 3. The Strategic Management of the Company: Industrial Aspects, Jean-Pierre Dal Pont. Part 2: Process Development and Industrialization 4. Chemical Engineering and Process Engineering, Jean-Pierre Dal Pont. 5. Foundations of Process Industrialization, Jean-François Joly. 6. The Industrialization Process: Preliminary Projects, Jean-Pierre Dal Pont and Michel Royer. 7. Lifecycle Analysis and Eco-Design: Innovation Tools for Sustainable Industrial Chemistry, Sylvain Caillol. 8. Methods for Design and Evaluation of Sustainable Processes and Industrial Systems, Catherine Azzaro-Pantel. 9. Project Management Techniques: Engineering, Jean-Pierre Dal Pont. Part 3: The Necessary Adaptation of the Company for the Future 10. Japanese Methods, Jean-Pierre Dal Pont. 11. Innovation in Chemical Engineering Industries, Oliver Potier and Mauricio Camargo. 12. The Place of Intensified Processes in the Plant of the Future, Laurent Falk. 13. Change Management, Jean-Pierre Dal Pont. 14. The Plant of the Future, Jean-Pierre Dal Pont.Table of ContentsForeword xv Richard DARTON Foreword xvii Jean PELIN Introduction xix Jean-Pierre DAL PONT Acknowledgments xxv PART 1: THE COMPANY AS OF TODAY 1 Chapter 1. The Industrial Company: its Purpose, History, Context, and its Tomorrow? 3 Jean-Pierre DAL PONT 1.1. Purpose, structure, typology 4 1.2. A centennial history 8 1.3. New challenges imposed by globalization and sustainable development 24 1.4. Our planet 32 1.5. The company of tomorrow. Some thoughts 45 1.6. Bibliography 49 Chapter 2. The Two Modes of Operation of the Company – Operational and Entrepreneurial 51 Jean-Pierre DAL PONT 2.1. Operational mode 53 2.2. Entrepreneurial mode, project management – the operational/entrepreneurial conflict 96 2.3. Bibliography 99 Chapter 3. The Strategic Management of the Company: Industrial Aspects 101 Jean-Pierre DAL PONT 3.1. Systemic view of the industrial company 102 3.2. Strategy and strategic analysis of the company 103 3.3. Development of the strategic plan: its deliverables 107 3.4. Technological choices and vocations 108 3.5. Bibliography 111 PART 2: PROCESS DEVELOPMENT AND INDUSTRIALIZATION 113 Chapter 4. Chemical Engineering and Process Engineering 115 Jean-Pierre DAL PONT 4.1. History of chemical engineering and process engineering 115 4.2. Process engineering 119 4.3. The chemical reactor 121 4.4. Bioreactors 126 4.5. Transportation and transfers 129 4.6. Unit operations 131 4.7. Separation processes: process engineering and the new challenges for life sciences 141 4.8. Acknowledgments 144 4.9. Bibliography 145 Chapter 5. Foundations of Process Industrialization 147 Jean-François JOLY 5.1. Introduction 147 5.2. The various stages of process development: from research to the foundations of industrialization 148 5.3. The pre-study (or pre-development process) 149 5.4. Development stage of the process 157 5.5. General conclusion 184 5.6. Bibliography 186 5.7. List of acronyms 188 Chapter 6. The Industrialization Process: Preliminary Projects 189 Jean-Pierre DAL PONT and Michel ROYER 6.1. Steps of industrialization 192 6.2. Bases of industrialization or process development 193 6.3. Feasibility study 194 6.4. Cost and typical duration of industrialization studies 198 6.5. Content of an industrialization project – conceptual engineering 199 6.6. Typical organization of an industrialization project 201 6.7. Business/industrial interface 202 6.8. Typology of industrialization projects 204 6.9. The industrial preliminary projects 205 6.10. Selection of production sites 209 6.11. The consideration of sustainability in the preliminary projects 210 6.12. Tips for conducting preliminary projects 215 6.13. Modification of the project scope 222 6.14. Host site 223 6.15. Reporting 228 6.16. Bibliography 232 Chapter 7. Lifecycle Analysis and Eco-Design: Innovation Tools for Sustainable Industrial Chemistry 233 Sylvain CAILLOL 7.1. Contextual elements 233 7.2. The chemical industry mobilized against upheavals 237 7.3. The lifecycle analysis, an eco-design tool – definitions and concepts 243 7.4. Innovation through eco-design 258 7.5. Limits of the tool 267 7.6. Conclusion: the future of eco-design 271 7.7. Bibliography 273 Chapter 8. Methods for Design and Evaluation of Sustainable Processes and Industrial Systems 275 Catherine AZZARO-PANTEL 8.1. Introduction 275 8.2. AIChE and IChemE metrics 279 8.3. Potential environmental impact index (waste reduction algorithm) 286 8.4. SPI (Sustainable Process Index) 292 8.5. Exergy as a thermodynamic base for a sustainable development metrics 294 8.6. Indicators resulting from a lifecycle assessment 294 8.7. Process design methods and sustainable systems 297 8.8. Conclusion 299 8.9. Bibliography 301 Chapter 9. Project Management Techniques: Engineering 307 Jean-Pierre DAL PONT 9.1. Engineer and engineering 307 9.2. Project organization 310 9.3. Management tools for industrial projects 314 9.4. The engineering project: from Process Engineering to the start of the facility 331 9.5. The amount of investment 346 9.6. Profitability on investment [DOR 81, MIK 10] 350 9.7. Conclusion 353 9.8. Bibliography 353 PART 3: THE NECESSARY ADAPTATION OF THE COMPANY FOR THE FUTURE 355 Chapter 10. Japanese Methods 357 Jean-Pierre DAL PONT 10.1. Japan from the Meiji era to now. The origin of the Japanese miracle 357 10.2. W.E. Deming and Japan 359 10.3. The Toyoda family – Taiichi Ohno – The Toyota Empire 362 10.4. Toyotism 363 10.5. The American response 368 10.6. Bibliography 369 Chapter 11. Innovation in Chemical Engineering Industries 371 Oliver POTIER and Mauricio CAMARGO 11.1. Definition of innovation 372 11.2. Field of innovation in the chemical engineering industry 376 11.3. The need for innovation 377 11.4. Methods for innovation in chemical engineering industry 380 11.5. Conclusion 395 11.6. Bibliography 396 Chapter 12. The Place of Intensified Processes in the Plant of the Future 401 Laurent FALK 12.1. Process intensification in the context of sustainable development 401 12.2. Main principles of intensification 404 12.3. Connection between intensification and miniaturization 408 12.4. Applications 414 12.5. New economic models implied by process intensification 416 12.6. Conclusion 429 12.7. Bibliography 430 Chapter 13. Change Management 437 Jean-Pierre DAL PONT 13.1. The company: adapt or die 438 13.2. The company: processes and know-how 438 13.3. Human aspects of change 444 13.4. Basic tools for change management 447 13.5. Changes and improvement of the industrial facility 454 13.6. Re-engineering, the American way 461 13.7. Conclusion 462 13.8. Bibliography 463 Chapter 14. The Plant of the Future 465 Jean-Pierre DAL PONT 14.1. Developed countries – companies – industrial firms 466 14.2. Typology of means of production 469 14.3. Product and plant design 473 14.4. Management of production and operations (MPO) 477 14.5. The IT revolution – IT management 479 14.6. And the individual? 480 14.7. Conclusion 481 14.8. Bibliography 482 List of Authors 485 Index 487
£180.45
ISTE Ltd and John Wiley & Sons Inc Grain Boundaries and Crystalline Plasticity
Book SynopsisThe main purpose of this book is to put forward the fundamental role of grain boundaries in the plasticity of crystalline materials. To understand this role requires a multi-scale approach to plasticity: starting from the atomic description of a grain boundary and its defects, moving on to the elemental interaction processes between dislocations and grain boundaries, and finally showing how the microscopic phenomena influence the macroscopic behaviors and constitutive laws. It involves bringing together physical, chemical and mechanical studies. The investigated properties are: deformation at low and high temperature, creep, fatigue and rupture.Table of ContentsPreface xi Chapter 1. Grain Boundary Structures and Defects 1 Jany THIBAULT-PENISSON and Louisette PRIESTER 1.1. Equilibrium structure of grain boundaries 1 1.2. Crystalline defects of grain boundaries 18 1.3. Conclusion 41 1.4. Bibliography 42 Chapter 2. Elementary Grain Boundary Deformation Mechanisms 47 Jean-Philippe COUZINIE and Louisette PRIESTER 2.1. Dislocation in close proximity to a grain boundary 48 2.2. Elastic interaction between dislocations and grain boundaries: image force 49 2.3. Short range (or core) interaction between dislocations and grain boundaries 52 2.4. Relaxation of stress fields associated with extrinsic dislocations 81 2.5. Relationships between elementary interface mechanisms and mechanical behaviors of materials 98 2.6. Bibliography 102 Chapter 3. Grain Boundaries in Cold Deformation 109 Colette REY, Denis SOLAS and Olivier FANDEUR 3.1. Introduction 109 3.2. Plastic compatibility and incompatibility of deformation at grain boundaries 111 3.3. Internal stresses in polycrystal grains 117 3.4. Modeling local mechanical fields using the finite element method (FEM)129 3.5. Hall-Petch’s law, geometrically necessary dislocations 139 3.6. Sub-grain boundaries and grain boundaries in deformation and recrystallization 145 3.7. Conclusion 155 3.8. Bibliography 156 Chapter 4. Creep and High Temperature Plasticity: Grain Boundary Dynamics 165 Sylvie LARTIGUE-KORINEK and Claude Paul CARRY 4.1. Introduction 165 4.2. Grain boundaries and grain growth 168 4.3. Grain boundaries and creep: mechanisms and phenomenological laws 174 4.4. Grain boundaries and superplasticity 197 4.5. Prospects: creep of nanograined materials 208 4.6. Bibliography 209 Chapter 5. Intergranular Fatigue 217 André PINEAU and Stephen ANTOLOVICH 5.1. Introduction 217 5.2. Low temperature intergranular fatigue 221 5.3. High temperature fatigue 252 5.4. Conclusion 271 5.5. Acknowledgements 272 5.6. Bibliography 272 Chapter 6. Intergranular Segregation and Crystalline Material Fracture 281 Anna FRACZKIEWICZ and Krzysztof WOLSKI 6.1. Grain boundaries and fracture 282 6.2. Intergranular segregation 286 6.3. Segregation and intergranular fracture 297 6.4. Intergranular fracture induced by liquid metals 308 6.5. General conclusion 320 6.6. Bibliography 321 APPENDICES 327 Appendix 1. Bicrystallography and Topological Characterization of Interfacial Defects 329 Sylvie LARTIGUE-KORINEK and Louisette PRIESTER Appendix 2. Appendices of Chapter 3 333 Colette REY, Denis SOLAS and Olivier FANDEUR List of Authors 341 Index 343
£167.15
Logos Verlag Berlin GmbH Adaptive Polynomial Tabulation: A Computationally
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£63.68
Logos Verlag Berlin GmbH Numerical Modeling of Emissions and
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£999.99
