Veterinary medicine Books

Book SynopsisThe latest edition of the seminal reference on the care and management of laboratory and research animals The newly revised ninth edition of The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals delivers an up-to-date and authoritative exploration on worldwide developments, current thinking, and best practices in the field of laboratory animal welfare science and technology. The gold standard in laboratory and captive animal care and management references, this latest edition continues the series' tradition of excellence by including brand-new chapters on ethical review, the care of aged animals, and fresh guidance on the care of mole rats, corvids, zebrafish, and decapods. The book offers introductory chapters covering a variety of areas of laboratory animal use, as well as chapters on the management and care of over 30 different taxa of animals commonly utilised in scientific procedures and research around the world. It also provides: A thorough introduction to the design of animal experiments, laboratory animal genetics, and the phenotyping of genetically modified miceComprehensive explorations of animal welfare assessment and the ethical review processPractical discussions of legislation and oversight of the conduct of research using animals from a global perspectiveIn-depth examinations of the planning, design, and construction of efficient animal facilities, special housing arrangements, and nutrition, feeding, and animal welfare The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals Ninth Edition is essential for laboratory animal scientists, veterinarians, animal care staff, animal care regulatory authorities, legislators, and professionals working in animal welfare non-governmental organizations.

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Book SynopsisDiscover a unique approach of combining descriptive anatomy with clinical information on the abdomen and pelvis of domestic mammals King's Applied Anatomy of the Abdomen and Pelvis of the Domestic Mammals delivers a thorough and accessible exploration of the abdominal and pelvic anatomy of domestic animals in a clinically relevant style. Designed as a refresher for veterinary students beginning to engage in clinical procedures, the book uses clinical illustration to teach the essential principles of how the abdomen and pelvis of domestic mammals are constructed. It covers core topics such as: Thorough introductions to the body wall, the mesenteries and ligaments of the abdomen and pelvis, and the gastrointestinal tract Explorations of the liver and the pancreas, the spleen and abdominal lymphatics, and the biology of digestion Practical discussions of the autonomic and somatic nerves of the abdomen and pelvis and the male and femTable of ContentsForeword xiii Preface xv Acknowledgements xvii About the Author xix About the Contributors xix About the Companion Website xxi 1 The Boundaries of the Abdomen 1 1.1 Introduction 1 1.2 The Diaphragm 1 1.3 The Layers of the Abdominal Wall 2 1.3.1 The skin 2 1.3.2 The subcutaneous fascia 2 1.3.3 The rectus abdominis muscle 2 1.3.4 External abdominal oblique muscle 3 1.3.5 Internal abdominal oblique muscle 5 1.3.6 Transverse abdominal muscle 6 1.3.7 Retroperitoneal fascia 7 1.3.8 Parietal peritoneum 8 1.4 The Sheath of the Rectus Abdominis Muscle 8 1.5 Clinical Importance of the Ventral Body Wall 8 1.6 The Inguinal Canal 9 1.7 Hernias 11 1.7.1 Inguinal hernia 11 1.7.2 Umbilical hernia 11 1.7.3 Perineal hernia 11 1.7.4 Diaphragmatic hernia 12 1.7.5 Post-operative hernia 12 2 Gastrointestinal Function 13 2.1 Introduction 13 2.2 Functions of the Alimentary Tract 13 2.2.1 Transport of food 13 2.2.2 Physical treatment of food 14 2.2.3 Chemical treatment of food 14 2.2.4 Absorption 15 2.3 Regions of the Alimentary Tract 15 2.4 Clinical Conditions Affecting Gastrointestinal Function 17 3 The Mesenteries, Ligaments and Omenta 19 3.1 The Greater Omentum 19 3.2 The Clinical Significance of the Greater Omentum 20 3.3 The Lesser Omentum 20 3.4 Ligaments 20 3.4.1 Abdominal ligaments 21 3.4.2 Pelvic ligaments 21 3.4.3 Pelvic ligaments – female 21 3.4.4 Pelvic ligaments – male 22 4 The Stomach 23 4.1 Overview of the Mammalian Stomach 23 4.2 Species Variations 23 4.2.1 Horse 23 4.2.2 Ox 25 4.2.3 Sheep 26 4.2.4 Pig 27 4.2.5 Dog 27 4.3 Clinical Conditions 28 4.3.1 Horse 28 4.3.2 Ox 28 4.3.3 Sheep 28 4.3.4 Pig 29 4.3.5 Dog 29 5 The Small Intestines 31 5.1 Duodenum, Jejunum and Ileum 31 5.2 Species Variations 32 5.2.1 Horse 32 5.2.2 Ox 33 5.2.3 Sheep 34 5.2.4 Pig 34 5.2.5 Dog 34 5.3 Clinical Conditions 36 5.3.1 Horse 36 5.3.2 Ox 36 5.3.3 Sheep 36 5.3.4 Pig 36 5.3.5 Dog 36 6 The Large Intestine 39 6.1 Overview 39 6.2 Species Variations 39 6.2.1 Horse 39 6.2.2 Ox 41 6.2.3 Sheep 42 6.2.4 Pig 42 6.2.5 Dog 43 6.3 Clinical Conditions 43 7 The Liver and Pancreas 45 7.1 The Liver 45 7.2 Anatomy of the Liver 45 7.3 Histology of the Liver 46 7.4 The Gall Bladder 46 7.5 Species Variations 47 7.5.1 Horse 47 7.5.2 Ruminants 47 7.5.3 Pig 48 7.5.4 Dog and Cat 49 7.6 The Pancreas 49 7.7 Clinical Conditions of the Liver and Pancreas 49 8 Arteries of the Abdomen and Pelvis 51 8.1 The Branches of the Abdominal Aorta 51 8.1.1 Coeliac artery 52 8.1.2 Cranial mesenteric artery 53 8.1.3 Phrenicoabdominal arteries 54 8.1.4 Renal arteries 54 8.1.5 Lumbar segmental arteries 55 8.1.6 Gonadal arteries 55 8.1.7 Caudal mesenteric artery 55 8.1.8 Deep circumflex iliac arteries 55 8.1.9 External iliac arteries 55 8.1.10 Internal iliac arteries 55 8.2 Species Variations 56 9 Veins of the Abdomen and Pelvis 57 9.1 Tributaries of the Caudal Vena Cava 57 9.1.1 Deep circumflex iliac veins 57 9.1.2 Lumbar veins 57 9.1.3 The gonadal veins 58 9.1.4 Renal veins 58 9.1.5 Phrenicoabdominal veins 58 9.1.6 Hepatic veins 59 9.1.7 Phrenic veins 59 9.2 The Hepatic Portal Vein 59 9.3 The Mammary Glands 59 9.3.1 Species variations 60 10 Lymphatics and the Spleen 63 10.1 The Lymphatic System 63 10.2 The Spleen 64 10.3 Species Variations 64 10.3.1 Horse 64 10.3.2 Ruminants 66 10.3.3 Pig 66 10.3.4 Carnivore 66 10.3.5 Whale 66 10.4 Clinical Conditions Affecting the Lymphatic System 66 11 The Nerves of the Abdomen and Pelvis 69 11.1 General Somatic Afferent Neurons 69 11.2 General Visceral Afferent Neurons 69 11.3 General Somatic Efferent Neurons 70 11.4 General Visceral Efferent Neurons 70 11.4.1 Sympathetic motor pathways 70 11.4.2 The prevertebral ganglia 73 11.4.3 Sympathetic transmitter substances 74 11.4.4 Pain pathways from the abdominal viscera 74 11.4.5 Parasympathetic motor pathways 74 11.5 Clinical Conditions 75 11.6 Regional Anaesthesia 77 11.6.1 Paravertebral anaesthesia 77 11.6.2 Pudendal nerve block 77 12 The Kidneys 79 12.1 Nitrogenous Excretion 79 12.2 Gross Anatomy of the Kidneys 80 12.3 Species Variations 81 12.3.1 Horse 81 12.3.2 Ox 82 12.3.3 Sheep 82 12.3.4 Pig 82 12.3.5 Dog/cat 82 12.4 Clinical Conditions of the Kidneys of the Domestic Mammals 82 12.5 Urinary Bladder and Urethra 83 12.6 Adrenal Gland 83 12.6.1 The blood supply of the adrenal gland 84 13 The Ovaries and Ovarian Bursae 85 13.1 The Ovary 85 13.2 Species Variations 86 13.2.1 Mare 86 13.2.2 Cow 87 13.2.3 Ewe 87 13.2.4 Sow 87 13.2.5 Bitch 87 13.2.6 Queen 88 13.3 The Ovarian Bursa 88 13.4 The Uterine Tube, also called the Fallopian Tube or the Oviduct 88 14 The Uterus, Uterine Tube, Vestibule and Vagina 89 14.1 The Uterine Cornu 89 14.1.1 Species variations 89 14.2 The Body of the Uterus 92 14.3 The Pregnant Uterus 93 14.3.1 Species variations 93 14.4 Placentation 94 14.4.1 The foetal membranes 95 14.5 The Cervix Uteri 95 14.5.1 Species variations 95 14.6 The Vagina 96 14.7 The Vestibule 97 14.7.1 Species variations 98 14.8 Clinical Conditions 99 15 The Mammalian Penis 101 15.1 The Penis 101 15.2 Erectile Tissue 101 15.2.1 Corpus spongiosum penis 101 15.2.2 Corpus cavernosum penis 102 15.3 The Muscles of the Penis 102 15.3.1 Retractor penis muscle 102 15.3.2 Ischiocavernosus muscle 102 15.3.3 Bulbospongiosus muscle 102 15.4 The Blood Supply and Venous Drainage of the Penis 103 15.5 Species Variations of the Penis 103 15.5.1 Horse 103 15.5.2 Ox 104 15.5.3 Sheep 105 15.5.4 Pig 107 15.5.5 Dog 109 15.5.6 Cat 110 15.6 The Prepuce 110 15.6.1 The muscles of the prepuce 111 15.6.2 The blood supply of the prepuce 111 15.6.3 Species variations of the prepuce 111 16 The Testes 113 16.1 The Anatomy of the Testes 113 16.2 Species Variations 113 16.3 The Scrotum 113 16.4 The Tissue Layers of the Testes and Scrotum 115 16.5 The Blood Supply and Drainage of the Testes 117 16.6 The Epididymis 118 16.7 Species Variations 118 16.7.1 Horse 118 16.7.2 Ruminant 118 16.7.3 Pig 118 16.7.4 Dog 118 16.8 The Descent of the Testes 118 16.9 Induction of Testicular Descent 121 17 The Accessory Sex Glands 123 17.1 The Accessory Glands 123 17.2 Prostate Gland 123 17.2.1 Species variations 123 17.3 Vesicular Glands 124 17.3.1 Species variations 124 17.4 Ampulla of the Ductus Deferens 125 17.5 Bulbourethral Glands 125 17.6 Clinical Conditions of the Accessory Glands 125 17.7 Anal Glands 125 18 Diagnostic Imaging of the Abdomen 127 18.1 Radiographic Anatomy 127 18.2 Specific Organs 128 18.2.1 The stomach 128 18.2.2 The spleen 129 18.2.3 The liver 129 18.2.4 The intestines 129 18.2.5 The kidneys 130 18.2.6 Urinary bladder 132 18.2.7 Urethra and prostate gland 132 18.3 Magnetic Resonance Imaging (MRI) 132 18.4 Computed Tomography 133 18.5 Ultrasonography 133 18.6 Diagnostic Imaging in Equine Patients 135 18.7 Diagnostic Imaging in Farm Animals 137 18.8 Laparoscopy in Dogs and Cats 139 Appendix 141 Bibliography 147 Index 149

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Book SynopsisAn essential guide to the health care of honey bees Honey Bee Medicine for the Veterinary Practitioner offers an authoritative guide to honey bee health and hive management. Designed for veterinarians and other professionals, the book presents information useful for answering commonly asked questions and for facilitating hive examinations. The book covers a wide range of topics including basic husbandry, equipment and safety, anatomy, genetics, the diagnosis and management of disease. It also includes up to date information on Varroa and other bee pests, introduces honey bee pharmacology and toxicology, and addresses native bee ecology. This new resource: Offers a guide to veterinary care of honey beesProvides information on basic husbandry, examination techniques, nutrition, and moreDiscusses how to successfully handle questions and 'hive calls'Includes helpful photographs, line drawings, tables, and graphs Written for veterinary practitioners, veterinary students, veterinary technicians, scientists, and apiarists, Honey Bee Medicine for the Veterinary Practitioner is a comprehensive and practical book on honey bee health.Trade Review“…this book will serve as an excellent guide. The illustrations and photos of this book are consistently brilliant and very useful, which makes the book a rich fund for giving lectures. The book probably covers all veterinarians (and other target groups, including beekeepers) need from such a compendium.” - Bee World, December 2021"This new book is a significant contribution to both the veterinary and beekeeping literature....Although primarily written for a North American readership, British/European veterinary professionals and beekeepers alike will find this 400-page professional textbook a valuable and comprehensive resource. The price tag is fairly high, but it is essential reading for anyone who is seriously interested in honey bee medicine and is a must-have for vet school and beekeeping association libraries." - Vet Record, July 2022"Overall, this textbook is a comprehensive summary of information pertaining to honey bee medicine, with the target audience being the veterinary practitioner. While this book may [be] slightly advanced for the first-time bee doctor just dipping their toes into the area of invertebrate medicine, the book provides supplemental resources for practitioners to build their knowledge-base. This is a thorough and reliable resource for veterinarians branching out into the honey bee industry." - Journal of Exotic Pet Medicine, January 2023Table of ContentsList of Contributors ix Acknowledgments xi Honey Bee Medicine: A One Health Challenge xiiTerry Ryan Kane Section I Biology and Medical Foundations 1 1 Looking to Nature to Solve the Health Crisis of Honey Bees 3Robin W. Radcliffe and Thomas D. Seeley 2 The Superorganism and Herd Health for the Honey Bee 21Robin W. Radcliffe 3 Honey Bee Anatomy 33Cynthia M. Faux 4 Physiology of the Honey Bee -- Principles for the Beekeeper and Veterinarian 41Rolfe M. Radcliffe 5 The Honey Bee Queen 55Randy Oliver 6 Honey Bee Strains 73Dewey M. Caron 7 Wild Bees: Diversity, Ecology, and Stresors of Non-Apis Bees 81Margarita M. López-Uribe 8 Honey Bee Nutrition 93Randy Oliver 9 Honey Bee Microbiota and the Physiology of Antimicrobial Resistance 125Kasie Raymann 10 Honey Bee Pharmacology 135Gigi Davidson Section II Beekeeping Principles for Veterinarians 149 11 Equipment and Safety 151Adam J. Ingrao 12 The Apiarist 167Katie Lee and Gary S. Reuter 13 Basics of Apiary Design 179Brandon K. Hopkins 14 Clinical Examination of a Honey Bee Hive 183Jerry Hayes 15 Veterinary Regulations 191Christopher J. Cripps 16 Medical Records 201Marcie Logsdon and Terry Ryan Kane Appendix 16.1A Veterinary -- Client Management Agreement 205 Appendix 16.1B Sample Hive Record 207 17 Epidemiology and Biosecurity 209Kristen K. Obbink and James A. Roth Appendix 17.A Beekeeping Biosecurity and Best Practices Checklist 217 Section III Honey Bee Diseases, Disorders, and Special Topics 219 18 Parasite Transmission Between Hives and Spillover to Non-Apis Pollinators 221Scott McArt 19 Colony Collapse Disorder and Honey Bee Health 229Jay D. Evans and Yanping (Judy) Chen 20 The Parasitic Mite Varroa destructor: History, Biology, Monitoring, and Management 235David T. Peck 21 Honey Bee Viral Diseases 253Esmaeil Amiri, Olav Rueppell, and David R. Tarpy 22 Honey Bee Bacterial Diseases 277Meghan Milbrath 23 Honey Bee Fungal Diseases 295Yanping (Judy) Chen and Jay D. Evans 24 Honey Bee Parasites and Pests 307Britteny Kyle 25 Pesticides 321Reed M. Johnson 26 Diagnostic Sampling 329Dan Wyns 27 Necropsy of a Hive 339Dewey M. Caron 28 Common Husbandry Issues 351Charlotte Hubbard 29 Queen Rearing and Bee Breeding 363Krispn Given 30 The Future Direction of Honey Bee Veterinary Medicine 367Jeffrey R. Applegate, Jr. Resources 369 Notes on Editors and Contributors 373 Index 379

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Book SynopsisSustainable Swine Nutrition As climate change continues to have a significant impact on the modern world, it is crucial to find alternative sources of energy and nutrients for swine production. The development of optimal feeding revolves around a multitude of considerationsgenetic variations in the pig, variability, availability, and stability of nutrients in feed ingredients, interactions among nutrients and non-nutritive factors, voluntary feed intake, physical (& social) environment of pigs, and more. Establishing the ideal network of factors will only grow in importance as humans assess the methods for our own food networks. Sustainable Swine Nutrition is a comprehensive book on swine nutrition, covering some fundamental aspects of nutritionnamely digestive physiology, water, protein or amino acids, lipids, carbohydrates, energy metabolism, vitamins, minerals, and nutrition and immunology. Providing the most up-to-date information on each of these areas, Table of ContentsContributors Preface Editor Part I Fundamental Nutrition Chapter 1 Digestive Physiology and Nutrition of SwineEugeni Roura, Maximiliano Mller, Roger Campbell, Michael Ryoo, and Marta Navarro Chapter 2 Water in Swine NutritionCharles M. Nyachoti, Alemu R. Hunde, and John F. Patience Chapter 3 Energy and Energy Metabolism in SwineJean Noblet, Etienne Labussière, David Renaudeau, and Jaap van Milgen Chapter 4 Lipids and Lipid Utilization in SwineWerner G. Bergen Chapter 5 Amino Acids and Amino Acid Utilization in SwineSai Zhang, Rodrigo Manjarin, and Nathalie L. Trottier Chapter 6 Carbohydrates and Carbohydrate Utilization in SwineKnud Erik Bach Knudsen, Helle Nygaard Lærke, and Henry Jørgensen Chapter 7 Vitamins and Vitamin Utilization in SwineJ. Jacques Matte and Charlotte Lauridsen Chapter 8 Minerals and Mineral Utilization in SwineGretchen M. Hill Chapter 9 Nutrition and Immunology in SwineLucas A. Rodrigues, Michael O. Wellington, Andrew G. Van Kessel, and Daniel A. Columbus Part II Nutrition for Successful and Sustainable Swine Production Chapter 10 Diet Formulation and Feeding ProgramsSung Woo Kim and Jeffrey A. Hansen Chapter 11 Cereal Grains, Cereal Grain Byproducts, and Alternative Energy SourcesRajesh Jha and Tofuko A. Woyengo Chapter 12 Major Protein Supplements in Swine DietsLee I. Chiba Chapter 13 Pulse Grains and Their Coproducts in Swine DietsLifang Wang, Eduardo Beltranena, and Ruurd T. Zijlstra Chapter 14 Fiber in Swine NutritionJ. Paola Lancheros, Charmaine D. Espinosa, Su A Lee, Maryane S. Oliveira, and Hans H. Stein Chapter 15 Anti-nutritional Factors in FeedstuffsTofuko A. Woyengo Chapter 16 Feed Processing Technology and Quality of FeedsChad B. Paulk and Charles R. Stark Chapter 17 Enzymes and Enzyme Supplementation of Swine DietsChan Sol Park and Olayiwola Adeola Chapter 18 Feed Additives in Swine DietsCormac J. O'Shea Chapter 19 Bioavailability of Amino Acids, Phosphorus, and OthersSu A Lee and Hans H. Stein Chapter 20 Swine Nutrition and EnvironmentMing Z. Fan, Brian J. Kerr, Steven Trabue, Xindi Yin, Zeyu Yang, and Weijun Wang Chapter 21 Swine Housing System, Behavior, and WelfarePeter J. Lammers, Mark S. Honeyman, Rachel Meredith Park, and Monique D. Pairis-Garcia Chapter 22 Feeding Reproducing Swine and Neonatal PigsLee J. Johnston Chapter 23 Feeding Weanling, Grower, and Finisher SwineRobert D. Goodband, Mariana B. Menegat, and Hayden E. Williams Chapter 24 Organic Swine Production and NutritionSandra A. Edwards Chapter 25 Swine Nutrition and Pork QualityJason K. Apple

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Book SynopsisThe newly revised Third Edition of Blackwell''s Five-Minute Veterinary Consult Clinical Companion: Small Animal Dentistry delivers an expertly edited quick-reference guide to all aspects of small animal dentistry. The book comprehensively describes new technologies and techniques as well as updated classifications and terminology. Readers willenjoy fast access to basic knowledge and detailed instructions for a wide variety of techniques in small animal dentistry. Newer technologies, like digital radiographs and advanced images, and newer techniques, like regional blocks, are combined with the latest in treatment information to provide readers with the most logically organized reference manual in the industry. The book's companion website offers video clips and client education handouts perfect for use in a busy veterinary practice. General practitioners will find this book to be a practical and indispensable resource. Readers will also enjoy: A thorTable of ContentsContributors Preface Acknowledgments Section I – Diagnostics Chapter 1 – Oral Examination and Charting Chapter 2 – Periodontal Probing Chapter 3 – Intraoral Radiology and Advanced Imaging Section II – Techniques Chapter 4 – Complete Dental Cleaning Chapter 5 – Periodontal Therapy Chapter 6 – Gingival Flaps Chapter 7 – Extraction Techniques Chapter 8 – Oral Pain Management Chapter 9 – Equipment, Instruments and Maintenance Section III - Oral/Dental Diseases – Developmental Oral/Dental Problems Chapter 10 – Persistent Deciduous Teeth Chapter 11 – Craniomandibular Osteopathy Chapter 12 – Enamel Hypocalcification Chapter 13 – Eruption Disruption Chapter 14 – Abnormal Tooth Number – Decreased Chapter 15 – Abnormal Tooth Number – Increased Chapter 16 – Abnormal Tooth Development and Structure Chapter 17 – Dentigerous Cysts Chapter 18 – Palatal Defects Chapter 19 – Malocclusions and Orthodontics Section IV – Acquired Oral/Dental Diseases – Periodontal Problems Chapter 20 – Periodontal Disease Chapter 21 – Gingival Enlargement Chapter 22 – Oronasal Fistula Chapter 23 – Stomatitis and Oral Ulceration Section V – Acquired Oral/Dental Diseases – Enamel and Dentin Problems Chapter 24 – Discolored Teeth Chapter 25 – Caries Chapter 26 – Attrition – Abrasion Section VI – Acquired Oral/Dental Diseases – Endodontic Problems Chapter 27 – Tooth Root Abscess Chapter 28 – Pulpitis Section VII – Acquired Oral/Dental Diseases – Neoplasia Chapter 29 – Odontogenic Tumors Chapter 30 – Odontoma Chapter 31 – Papillomatosis Chapter 32 – Melanocytic Tumors – Oral Chapter 33 – Fibrosarcoma Chapter 34 – Squamous Cell Carcinoma Chapter 35 – Malignant Tumors – Others Chapter 36 – Benign Masses and Lesions Section VIII – Acquired Oral/Dental Diseases – Trauma Chapter 37 – Tooth-Dentoalveolar Injuries Chapter 38 – Maxillary and Mandibular Fractures Chapter 39 – Temporomandibular Joint (TMJ) Disorders Section IX – Feline Oral/Dental Disease Chapter 40 – Tooth Resorption Chapter 41 – FCGS – Feline Chronic Gingivostomatitis Chapter 42 – Chronic Osteitis – Alveolitis Chapter 43 – Feline Infectious Diseases - Oral Involvement Section X – Special Categories Chapter 44 – Salivary Gland Disorders Chapter 45 – Other Soft Tissue Disorders Appendices Appendix A – The Use of Antibiotics in Veterinary Dentistry (AVDC Position Statement, accessed September 7, 2020) Appendix B - Companion Animal Dental Scaling Without Anesthesia (AVDC Position Statement, accessed September 7, 2020) Appendix C – American Veterinary Dental College Nomenclature Appendix D – Internet Resources Appendix E – Dental Home Care

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Book SynopsisA fully updated new edition of the only text solely focused on anesthesia of dogs and cats with co-existing disease The revised Second Edition of Canine and Feline Anesthesia and Co-Existing Disease expands and updates the only book solely dedicated to practical anesthetic techniques for dogs and cats with co-existing disease. The book now includes additional images in full color, new discussions of cutting-edge drugs and techniques, and updated chapters and information throughout. This text provides in-depth and clinically-useful information that can easily be incorporated into the progressive companion animal practice. It offers more than 200 new images and 4 new chapters focusing on urogenital concerns, genetic diseases, nociceptive disorders, and cardiopulmonary resuscitation and post-resuscitation care. It is intuitively organized by body system to allow for quick and easy reference. Key features: Presents concise, yet comprehensive anesthetTable of Contents1. Cardiovascular Disease Jonathan M. Congdon 2. Respiratory Disease Rebecca A. Johnson and David B. Brunson 3. Neurologic Disease Erin Wendt-Hornickle and Daniel Almeida 4. Hepatobiliary Disease Carrie A. Schroeder 5. Gastrointestinal Disease Juliana Peboni Figueiredo 6. Renal Disease Carrie A. Schroeder 7. Urogenital Concerns Carrie A. Davis 8. Perioperative Fluid, Electrolyte, and Acid-Base Disturbances Carolyn L. Kerr 9. Endocrine Disease Berit L. Fischer 10. Nutritional Disease Lindsey B.C. Snyder 11. Genetic Disease Tania Perez Jimenez 12. Anesthesia for Ophthalmic Patients Phillip Lerche 13. Oral and Maxillofacial Disorders Christopher J. Snyder and Jason W. Soukup 14. Hematologic Disorders Molly Shepard and Benjamin Brainard 15. Skin and Musculoskeletal Diseases Paulo V.M. Steagall 16. Infectious Disease Bradley T. Simon and Jusmeen Sarkar 17. Neoplastic Disease Verónica Salazar 18. Cesarean Section and Pregnancy Turi K. Aarnes and Melissa A. Murdock 19. Neonatal and Pediatric Concerns Anderson Fávaro da Cunha 20. Senior and Geriatric Concerns Anderson Fávaro da Cunha 21. Disorders Related to Trauma Andre Shih 22. Nociceptive Disorders Andrew Claude 23. Cardiopulmonary Resuscitation and Post-Cardiac Arrest (PCA) Care Thomas K. Day

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Book SynopsisEquine Neonatal Medicine A comprehensive guide to medical care for pregnant mares and neonatal foals Equine Neonatal Medicine offers an in-depth comprehensive reference for the clinical management of pregnant and periparturient mares and neonatal foals. Edited by leading experts in the field and written by experienced equine specialists, this textbook covers all aspects of providing veterinary care to mares and neonatal foals. Encompassing physiology, pathophysiology, theory, and practice, this textbook offers an authoritative, well-illustrated reference to equine perinatology. Topics covered include fetal monitoring, parturition, and peri-parturient disorders in the mare as well as diagnostic and therapeutic options for ill neonatal foals. The book: Covers aspects of veterinary care for the pregnant and peri-parturient mare and how to diagnose and treat the ill neonateDiscusses fetal monitoring and parturition, and peri-parturient disorders in the marePresents an exhaustive, detailed, and comprehensive reference for any veterinary practitioner involved with breeding management of horses and the care of neonatal foalsProvides a clinical perspective, including both theory and practiceFeatures more than 600 color images and diagrams to demonstrate the concepts discussed Equine Neonatal Medicine is an essential reference for any veterinary practitioner engaged with mares and foals, including specialists in equine medicine, equine and mixed animal practitioners, ambulatory practitioners, and veterinary students.

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Book SynopsisAn updated and comprehensive reference to pathology in every organ system in genetically modified mice The newly revised and thoroughly updated Second Edition of Pathology of Genetically Engineered and Other Mutant Mice delivers a comprehensive resource for pathologists and biomedical scientists tasked with identifying and understanding pathologic changes in genetically modified mice. The book is organized by body system, includes descriptions and explanations of a wide range of findings, as well as hundreds of color photographs illustrating both common and rare lesions that may be found in genetically engineered and wild type mice. The book is written by experienced veterinary and medical pathologists working in veterinary medical colleges, medical colleges, and research institutes. Covering the latest discoveries in mouse pathology resulting from advancements in biotechnology research over the last 30 years, this singular and accessible resource is a must-read for veterinary and mediTable of ContentsList of Contributors vii Preface and Acknowledgments x 1 Introduction to Mouse Pathology 1 Jerrold M. Ward, Peter Vogel, and John P. Sundberg 2 The Mouse Online: Open Mouse Biology and Pathology Data Resources for Biomedical Research 6 Dale A. Begley, Paul N. Schofield, and John P. Sundberg 3 Mouse Genetic Nomenclature: The Underpinning of Mouse Genetics 22 John P. Sundberg, Dale A. Begley, Melissa L. Berry, Michelle N. Perry, David Shaw, and Paul N. Schofield 4 Discovering and Validating Mouse Models of Human Diseases: The Cinderella Effect 39 John P. Sundberg, Jerrold M. Ward, Peter Vogel, and Paul N. Schofield 5 Embryos, Placentas, and Neonates 48 Brad Bolon and Jerrold M. Ward 6 Ciliopathies 72 Peter Vogel and Laura J. Janke 7 Hematopoietic and Lymphoid Tissues 82 Harm HogenEsch and John P. Sundberg 8 Mouse Hematolymphoid Neoplasms 97 Jerold E. Rehg 9 Immunodeficient and Humanized Mice 132 Sara F. Santagostino, Sébastien Monette, Alessandra Piersigilli, Virginia L. Godfrey, and Harm HogenEsch 10 Skin, Hair, and Nails 159 John P. Sundberg, Lloyd E. King, Jr, and Raoul V. Kuiper 11 Mammary Gland 213 Alexander D. Borowsky and Robert D. Cardiff 12 The Respiratory Tract 237 Jerrold M. Ward and John P. Sundberg 13 The Gastrointestinal Tract 259 Jerrold M. Ward, Piper M. Treuting, and M. Kay Washington 14 Cardiovascular System 284 Kathleen L. Gabrielson, Akash Behera, Polina Sysa-Shah, Tyler J. Creamer, and Timothy K. Cooper 15 Liver and Pancreas 307 Maria L.Z. Dagli, Lucas M. Chaible, and Katja Steiger 16 Neuromuscular System 336 Peter Vogel, Laura J. Janke, and Heather W. Sheppard 17 Endocrine System 355 Krista M. D. La Perle 18 Kidney and Urinary Bladder 378 Jeffrey B. Kopp, Avi Z. Rosenberg, Cory F. Brayton, Jeffrey I. Everitt, and Jerrold M. Ward 19 Female Reproductive System 403 Darlene Dixon and Alexander Yu. Nikitin (In Memory of Dr. Joel Mahler) 20 Male Reproductive System 431 Sue E. Knoblaugh, Hibret A. Adissu, Colin McKerlie, and Robert D. Cardiff 21 Nervous System 462 Jessica M. Snyder, Katherine N. Gibson-Corley, and Enrico Radaelli 22 Eye and Ear 493 Heather W. Sheppard, Laura J. Janke, Jerold E. Rehg, and Peter Vogel 23 Bones and Teeth 520 Peter Vogel, John P. Sundberg, and Cheryl Ackert-Bicknell Index 541

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Book SynopsisA fully updated new edition of thispractical guide to managing anesthesia in horsesand other equids, providingupdated and expanded informationina concise, easy-to-read format Manual of Equine Anesthesia and Analgesiaprovides practitioners and veterinary students withconcise, highly practicalguidance toanesthetizing horses,donkeys,and mules.Using a bulleted quick-reference format,this popularresourcecoversthebasic physiological and pharmacologicalprinciples ofanesthesia,patientpreparationandmonitoring,and the management of sedation andanesthesia. Chapters written by leading veterinary anesthesiologistscontain numerous clinical imagesandillustrations, case examples, tables, diagrams, andboxedsummaries ofimportantpoints. Now in full color, thesecondeditionfeatures extensivelyrevised andupdatedinformation throughout. Newsections coverchronic pain, management of horses undergoing MRI, ventilators, nerve blocks for reproductive surgery, muscle relaxants, variousnew drugs, paravertebralanesthTable of ContentsList of Contributors xi Preface xv Acknowledgments xvi 1 Preoperative Evaluation and Patient Preparation 1 The Risk of Equine Anesthesia 1 Tanya Duke-Novakovski Patient Preparation 5 Tanya Duke-Novakovski 2 Serum Chemistry and Hematology 8 Carla Sommardahl 3 The Cardiovascular System 19 Physiology of the Cardiovascular System 19 Tamara Grubb Evaluation of the Cardiovascular System 36 Daniel G. Kenney 4 The Respiratory System 50 Anatomy of the Equine Respiratory System 50 Robert Reed Physiology of the Respiratory System 55 Carolyn Kerr Evaluation of the Respiratory System 67 Tom Doherty Airway Management 68 Tom Doherty Tracheostomy 78 Tanner Snowden and Jim Schumacher 5 The Renal System 86 Natalie S. Chow 6 Neurophysiology and Neuroanesthesia 98 Tanya Duke-Novakovski 7 The Autonomic Nervous System 110 Christine Egger 8 Electrolyte and Fluid Therapy 119 Electrolytes 119 Rachel A. Reed Fluid Therapy 125 Christopher K. Smith 9 Acid-Base Physiology 137 Traditional Approach 137 Alex Valverde and Tom Doherty Physicochemical Approach 147 Diego E. Gomez and Alex Valverde 10 Hemostasis and Hemotherapy 155 Hemostasis 155 Kira L. Epstein Hemotherapy 162 Kira L. Epstein 11 Thermoregulation 173 Chiara E. Hampton 12 Pharmacology of Drugs Used in Equine Anesthesia 184 Phenothiazines 184 Alicia Skelding Butyrophenones 186 Alicia Skelding α2-Adrenergic Agonists 188 Alicia Skelding Opioids 196 Alicia Skelding Trazadone 205 Alicia Skelding Benzodiazepines 206 Alicia Skelding Guaifenesin 209 Alicia Skelding Ketamine 210 Alicia Skelding Tiletamine and Zolazepam (TZ) 213 Alicia Skelding Alfaxalone 214 Alicia Skelding Propofol 216 Alicia Skelding Barbiturates 218 Alicia Skelding Intravenous lidocaine 219 Patricia Queiroz-Williams Horse-related drug Regulations in Europe 222 Regula Bettschart-Wolfensberger and Simone K. Ringer 13 Inhalational Anesthetics 223 Rachel A. Reed 14 Local Anesthetics 232 Catherine M. Creighton and Leigh Lamont 15 Neuromuscular Blocking Agents in Horses 244 Manuel Martin-Flores and Daniel M. Sakai 16 Non-steroidal Anti-Inflammatory Drugs and Corticosteroids 250 Non-steroidal Anti-Inflammatory Drugs 250 Stephanie Kleine Corticosteroids 259 Stephanie Kleine 17 Anesthetic Machines and Equipment 266 Rachel A. Reed 18 Positioning the Anesthetized Horse 287 Hui Chu Lin 19 Monitoring the Anesthetized Horse 294 Monitoring the Central Nervous System 294 Joanna C. Murrell Cardiovascular Monitoring 300 Alanna N. Johnson Respiratory Monitoring 310 Alanna N. Johnson Anesthetic Agent Monitoring 323 Alanna N. Johnson Monitoring Temperature 324 Chiara E. Hampton Monitoring Neuromuscular Function 328 Manuel Martin-Flores and Daniel M. Sakai 20 Standing Sedation 333 Catherine M. Creighton 21 General Anesthesia Techniques 339 Regula Bettschart-Wolfensberger and Simone K. Ringer 22 Anesthesia of the Head and Neck 352 Anesthesia of the Head 352 Jim Schumacher, John Schumacher, and Ray Wilhite Maxillary Nerve Block in Donkeys 358 Usama Hagag Cervical Plexus Block 363 Luis Campoy 23 Anesthesia of the Eye 369 Daniel S. Ward 24 Anesthesia of the Limbs 376 Jim Schumacher, John Schumacher, and Ray Wilhite 25 Anesthesia of the Perineum and Testicle 396 Pudendal Nerve Block – Electrostimulation Technique 396 Kirsty Gallacher and Luiz Santos Pudendal Nerve Block – Blind Approach 399 Jim Schumacher Local Anesthesia for Castration 400 Philip D. Jones 26 Anesthesia of the Abdominal Wall 404 Thoracolumbar Paravertebral Block (TPVB) – Electrostimulation Technique 404 Luiz Santos and Kirsty Gallacher Paravertebral Nerve Block – Blind Technique 406 Alex Valverde Transversus Abdominis Plane Block 409 Alex Valverde and Flavio SA. Freitag Caudal Intercostal Block for Abdominal Surgery (CIBAS) 413 Benjamin Gingold 27 Epidural Analgesia and Anesthesia 416 Alex Valverde 28 Pathophysiology of Pain 425 Rachel A. Reed 29 Pain Recognition in Horses 431 Karina B. Gleerup, Casper Lindegaard, and Pia Haubro Andersen 30 Management of Pain 450 The Pharmacologic Approach to Pain Management 450 Rachel A. Reed Rehabilitation Modalities for Acute and Chronic Pain in Horses 456 Tena L. Ursini Equine Acupuncture 462 Neal Valk 31 Anesthesia of Foals 472 Tom Doherty and Alex Valverde 32 Anesthesia of Horses with Intestinal Emergencies (Colic) 494 Tom Doherty 33 Anesthesia of the Geriatric Horse 501 Reza M. Seddighi 34 Anesthesia and Pregnancy 511 Lydia Donaldson 35 Anesthesia for Equine Imaging 522 Carrie A. Davis 36 Anesthesia of Donkeys and Mules 543 Anatomic, Physiologic, and Behavioral Differences 543 Suzanne L. Burnham Sedation and Anesthesia of Donkeys and Mules 548 Tom Doherty Donkey Pain Assessment Scales 552 Machteld van Dierendonck and Thijs van Loon 37 Remote Capture of Equids 565 Nigel Caulkett 38 Complications 573 Intraoperative Hypotension 573 Christopher K. Smith and Tom Doherty Intraoperative Hypertension 580 Tom Doherty Hypoxia and Hypoxemia 582 Rachel A. Reed Hypercarbia 588 Tom Doherty Pulmonary Edema as a Consequence of Airway Obstruction 590 Tom Doherty Endotoxemia 592 Tom Doherty Postanesthetic Myopathy 594 Krista B. Mitchell Neuropathy 599 Rachel A. Reed Hyperkalemic Periodic Paralysis (HYPP) 604 Alanna N. Johnson and Rachel A. Reed Malignant Hyperthermia 609 Alanna N. Johnson and Rachel A. Reed Delayed Awakening and Recovery 611 Tom Doherty Paraphimosis and Priaprism 614 Meggan Graves and Jim Schumacher Anaphylactic and Anaphylactoid Reactions 621 Rachel A. Reed Intra-carotid and Perivascular Injections 624 Rachel A. Reed Equine Cardiopulmonary Resuscitation 627 Genevieve Bussieres 39 Recovery from Anesthesia 633 Bernd Driessen 40 Euthanasia 653 Ron Jones and Tom Doherty Index 661

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Book SynopsisA clinical quick-reference guide to managing toxicants in horses Blackwell's Five-Minute Veterinary Consult Clinical Companion: Equine Toxicology provides crucial information for managing toxicants in horses in a quick-reference format. The book begins with foundational information on clinical toxicology, including emergency management, antidotes, sample analysis, and necropsy. It then discusses specific toxicant categories and toxicants of concern, organized alphabetically for fast access in emergency situations. The identically formatted topics offer key information relevant to managing toxicants in horses, plus clinical photographs depicting plants and drugs to help clinicians and students identify toxicants. A companion website presents the figures from the book for download in PowerPoint. This book is the ideal clinical resource for busy practitioners seeking immediate access to life-saving information in time-sensitive emergencies. It places all the information the reader needs to manage toxicants in horses at their fingertips, with full color images and concise bullet points. Blackwell's Five-Minute Veterinary Consult Clinical Companion: Equine Toxicology features: A thorough introduction to emergency management of the poisoned equine patient, as well as general principles of toxicants, antidotes, lab sample analysis, and necropsy analysisAn exploration of specific toxins and toxicants, including illicit and pharmaceutical drugs, envenomations, insecticides, herbicides, and farm chemicalsPractical discussions of metal, mycotoxin, rodenticide, and plant toxicology in horsesIn-depth discussion of intoxication by poisonous trees and miscellaneous toxins, like carbon monoxide, nitrates, nitrites, salt, smoke, and tropical materials Blackwell's Five-Minute Veterinary Consult Clinical Companion: Equine Toxicology is an indispensable reference for veterinary clinicians and students dealing with equine medicine, as well as for anyone seeking concise and comprehensive information about equine toxicology.Table of ContentsContributors List SECTION 1 CLINICAL TOXICOLOGY Chapter 1 Forensic Investigation of Equine Intoxications Chapter 2 Necropsy Analysis Chapter 3 Laboratory Testing Considerations Chapter 4 Treating an Intoxicated Animal: Antidotes and Therapeutic Medications Chapter 5 Compounded Medications SECTION 2 SPECIFIC TOXINS AND TOXICANTS Drugs: Illicit and Recreational Chapter 6 Cobalt Chapter 7 Cocaine Chapter 8 Dermorphin Chapter 9 Growth Hormones and Secretagogues Chapter 10 Marijuana Chapter 11 Methamphetamine and Amphetamine Chapter 12 Opioids Chapter 13 Selected Androgen (SARMS) and Estrogen (SERMS) Receptor Modulators Chapter 14 Synthetic Cannabinoids Drugs: Prescription Chapter 15 Antipsychotic Agents – Reserpine and Fluphenazine Chapter 16 Benzodiazepines Chapter 17 Beta2 Agonists – Clenbuterol and Albuterol Chapter 18 Bisphosphonates Chapter 19 Gabapentin Chapter 20 Iodine Chapter 21 Medroxyprogesterone Chapter 22 Methylxanthines: Caffeine, theobromine, theophylline Chapter 23 Nonsteroidal Anti-inflammatory Drugs (NSAIDS) Chapter 24 Thyroxine (Levothyroxine) Chapter 25 Vitamin D (calciferol) Insecticides, Herbicides and Farm Chemicals Chapter 26 Amitraz Chapter 27 Cholinesterase Inhibiting Carbamate Pesticides Chapter 28 Cholinesterase Inhibiting Organophosphate Pesticides Chapter 29 Fertilizers – nitrates, urea, phosphates and others Chapter 30 Herbicides Chapter 31 Paraquat and Diquat Chapter 32 Pentachlorophenol (PCP) Chapter 33 Pyrethroid and Pyrethrin Insecticides Ionophores and Growth Promotants Chapter 34 Ionophores Chapter 35 Ractopamine Chapter 36 Zilpaterol Metals Chapter 37 Arsenic Chapter 38 Fluoride Chapter 39 Iron Chapter 40 Lead Chapter 41 Selenium Mycotoxins / Fungus Chapter 42 Aflatoxins Chapter 43 Fescue (Endophyte-infected tall fescue) Chapter 44 Fumonisins Chapter 45 Fusaria Chapter 46 Slaframine Chapter 47 Tremorgenic Mycotoxins Other Toxins Chapter 48 Clostridium Botulinum toxin Chapter 49 Cyanide Chapter 50 Sodium Chloride (Salt) Plants and Biotoxins Chapter 51 Alsike clover (Trifolium hybridum) Chapter 52 Blue-Green algae (Cyanobacteria) Chapter 53 Cardiotoxic plants Chapter 54 Day blooming Jessamine (Cestrum spp.) Chapter 55 Death camus (Zigadenus spp.) Chapter 56 Hemlocks (Conium maculatum and Cicuta spp.) Chapter 57 Hoary alyssum (Berteroa incana) Chapter 58 Jimsonweed (Datura spp.) Chapter 59 Kleingrass (Panicum coloratum) Chapter 60 Lantana (Lantana camara) Chapter 61 Locoweeds (Astragalus spp. and Oxytropis spp.) Chapter 62 Narrow leaf milkweed (Asclepias fascicularis) Chapter 63 Nightshades (Solanum spp.) Chapter 64 Oleander (Nerium oleander and Cascabela thevetia) Chapter 65 Pyrrolizidine Alkaloids Chapter 66 Rayless goldenrod (Isocoma pluriflora) Chapter 67 Rhododendrons Chapter 68 Sudangrass (Sorghum spp.) Chapter 69 Tansy ragwort (Jacobea vulgaris) Chapter 70 White snake root (Ageratina altissima) Chapter 71 Yellowstar thistle / Russian knapweed (Centaurea solstitialis / Acroptilon repens) Chapter 72 Yew (Taxus spp.) Rodenticides Chapter 73 Anticoagulants Chapter 74 Bromethalin Chapter 75 Cholecalciferol Chapter 76 Phosphides Chapter 77 Sodium fluoroacetate (Compound 1080) Chapter 78 Strychnine Toxic Gases Chapter 79 Air Contaminants – CO, NH3, H2S Chapter 80 Smoke Trees Chapter 81 Black locust (Robinia pseudoacacia) Chapter 82 Black walnut (Juglans nigra) Chapter 83 Box elder (Acer negundo) Chapter 84 Oak (Quercus spp.) Chapter 85 Red maple (Acer rubrum) Zootoxins Chapter 86 Blister Beetles (Epicauta spp. and Pyrota spp.) Chapter 87 Snakes – Crotalids (pit vipers) Chapter 88 Snakes – Elapids (coral snakes) Chapter 89 Spiders – Brown recluse spider and black widow spider Section 3 Reference Material Appendix 1 Abbreviations Appendix 2 Herbicides Appendix 3 Information Resources for Toxicology INDEX

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Book SynopsisA completely revised and updated reference for farm animal anesthesia, sedation, and pain management The newly revised Second Edition of Farm Animal Anesthesia: Cattle, Small Ruminants, Camelids, and Pigs is a practical and easy-to-use manual for techniques associated with anesthesia and pain management in farm animal species. The new edition incorporates advances in surgical and diagnostic techniques, with the latest drugs and equipment, updated images, and new technique descriptions added throughout the book. Farm Animal Anesthesia offers additional and updated information on drug combinations and anesthetic techniques relevant to small ruminants and potbellied pigs, reflecting their growing popularity. New chapters and topics on paralytic drugs for complete muscle relaxation, use of ventilators for advanced and complex surgeries, updated local and regional anesthetic techniques, and comprehensive standing surgery and diagnostic procedures have bTable of ContentsContributing Authors Preface Chapter 1. Preanesthetic ConsiderationsHuiChu Lin Positioning Ruminal tympany Regurgitation Salivation Malignant hyperthermia Differences in sensitivity to anesthetics Preanesthetic preparation References Chapter 2. Commonly Used PreanestheticsHuiChu Lin Acepromazine (phenothiazine derivatives) Droperidol and azaperone (butyrophenone derivatives) Detomidine, dexmedetomidine, medetomidine, romifidine, and xylazine (α2 agonists) Atipamezole, tolazoline, yohimbine, and vatinoxan (α2 antagonists) Diazepam and midazolam (benzodiazepine derivatives) Chloral hydrate References Chapter 3. Standing Sedation and Chemical RestraintHuiChu Lin Cattle Small ruminants and camelids Swine References Chapter 4. Injectable Anesthetics and Field AnesthesiaHuiChu Lin Injectable anesthetics Ketamine Telazol Alfaxalone Guaifenesin Field anesthesia Cattle Small ruminants and camelids Swine References Chapter 5. Neuromuscular Blocking AgentsStuart Clark-Price Physiology of the neuromuscular junction Mechanism of action of NMBA Depolarizing neuromuscular blocking agents Non-depolarizing neuromuscular blocking agents Clinically useful NMBA Atracurium Cis-atracurium Vecuronium Rocuronium Monitoring of NMBA action Reversal of NMBA References Chapter 6. Inhalation Anesthesia and Use of VentilatorHuiChu Lin Cattle Small ruminants and camelids Swine Use of Ventilators References Chapter 7. Perioperative Monitoring and Management of ComplicationsHuiChu Lin Perioperative monitoring Supportive fluid therapy Positioning Recovery Perioperative complications Regurgitation and aspiration pneumonia Airway obstruction Ruminal tympany/bloat Salivation Hypoventilation Cardiac arrhythmias Hypotension Hypothermia Malignant hyperthermia Postanesthetic neuromyopathy Cardiovascular collapse References Chapter 8. Local and Regional Anesthetic TechniquesJessica Rush and Jenna Stockler Local anesthetic agents Anesthesia for dehorning Anesthesia for the eye and eyelids Nasal anesthesia Anesthesia for reproductive procedures and for cessation of straining Caudal epidural anesthesia Continuous caudal epidural anesthesia Internal pudendal nerve block Dorsal penile nerve block Sacral paravertebral nerve block Lumbosacral epidural anesthesia Anesthesia for laparotomy Line block Inverted L block Proximal paravertebral block Distal paravertebral block Anesthesia for udder and teats Anesthesia of the limbs Castration References Chapter 9. Anesthetic Management of Specific ProceduresBenjamin Newcomer Urogenital surgery in the male Castration Penile papilloma Persistent frenulum Penile translocation Epididymectomy Vasectomy Urogenital surgery in the female Cesarean section Ovariectomy Vaginal prolapse Perineal laceration Surgical disorders of the abdomen Laparotomy Disorders of the forestomachs Displacements and volvulus of the abomasum Small intestine disorders (intussusception, intestinal volvulus, intestinal obstruction) Urolithiasis and bladder rupture Umbilical hernias Musculoskeletal indications Dehorning Claw amputation and facilitated ankylosis Excision of interdigital fibromas Teeth Floating Tail docking Rectal prolapse Wounds, lumps, bumps, and abscesses Wound management Ocular squamous cell carcinoma Enucleation Entropion Abscess removal for caseous lymphadenitis References Chapter 10. Pain Management for Farm AnimalsHuiChu Lin Local anesthetics Systemic pain management Opioid analgesics Nonsteroidal anti-inflammatory drugs Alpha-2 agonists Ketamine Gabapentin Drug combinations for pain management Constant rate infusion Local or regional analgesia Caudal epidural analgesia Lumbosacral epidural anesthesia Intra-articular analgesia References Chapter 11. Fluid TherapyManuel F. Chamorro and Paul H. Walz General considerations Physiology of body fluids Patient assessment Fluid and electrolyte therapy in the perioperative period Quantity and rate of fluid administration Fluid type selection Fluid therapy in cases of calf diarrhea Fluid therapy in cases of acute ruminal acidosis (grain overload) Fluid therapy in cases of Hepatic lipidosis/Ketosis/Pregnancy toxemia Fluid therapy in cases of abomasal and small intestinal disorders Fluid therapy for cases of sepsis (septic peritonitis, septic omphalitis, etc.) Fluid therapy in cases of urinary tract obstruction/rupture Whole blood transfusions Method of administration Monitoring fluid administration References Chapter 12. Regulatory and Legal Considerations of Anesthetics and Analgesics Used in Food Producing AnimalsThomas Passler Alpha-2 agonists and antagonists Barbiturates Benzodiazepines Dissociative anesthetics Local anesthetics Opioids Non-steroidal anti-inflammatory drugs (NSAIDs) Phenothiazine Derivatives Propofol References ­­13. Euthanasia of Farm AnimalsThomas Passler Considerations prior to Euthanasia The Process of Euthanasia Methods of euthanasia Injectable euthanasia agents Physical methods Adjunctive and other methods of euthanasia Considerations Subsequent to Euthanasia References

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Book SynopsisDiagnostics and Therapy in Veterinary Dermatologypresentsthoroughcoverage of thelatest discoveries, drugs, and treatmentsfordermatologicconditions in animals. Chapters written byexperts in each respective areaofveterinarydermatologycontain up-to-date information onnewdiagnostic tools and tests,autoimmune diseases, parasitic and fungal infections,medical management of acute and chronicconditions, alternativedermatologictherapies,and more. Offering practicalsolutions forbothspecialist and general practice veterinarians dealing with dermatology cases, thiswide-rangingresource alsoaddressesantibiotic resistanceand misuse, theavailability of foods for elimination diet trials,problems with genericdrugs,emerging infectious diseases,and otherimportantproblemscurrentlyfacing the profession.Throughout the text,veterinary practitionersare provided with real-world guidance onimprovinghowtheywork uptheirdermatology casesand strengtheningcommunication between the primary care veterinarian and the dermatologist.Edited by aleadingboard-certifieddermatologist, thisvolume: Focuses on cats and dogsIncludesnumeroushigh-quality clinical photographsillustrating allkeyconceptsCoverstopics such ashow to use your nursing staff to the fullest,theOne Healthmovement, and howchanging climateisincreasing thespread ofcertain dermatologicdiseasesDiscusses approaches forbuildingabetter working relationship between clients, primary care veterinarians and dermatologistsProvides insights on the future of technology in the diagnosis and treatment of dermatologic diseases Covering the very latest developments in the field,Diagnostics and Therapy in Veterinary Dermatologyis essential reading for veterinary dermatologists, veterinary students, and any veterinary general practitioner with a dermatology caseload.Table of ContentsForeword Acknowledgments List of contributors Chapter 1: The skin as an immune organ Domenico Santoro and Megan Boyd Chapter 2: How to get the most out of your dermatologic history and examination Michelle Woodward O’Gorman Chapter 3: New diagnostic tools and tests for dermatology Amelia White Chapter 4: When, where, and how to biopsy skin Dawn Logas Chapter 5: Antibiotic-resistant staphylococcal infections Christine L. Cain Chapter 6: Fungal and oomycete infections Darcie Kunder Chapter 7: Parasitic infections Catlin Contreary Chapter 8: Emerging infectious diseases in veterinary dermatology Ana Milena Carmona-Gil Chapter 9: Canine hypersensitivities Rosanna Marsella Chapter 10: Feline hypersensitivities Cecilia Friberg Chapter 11: Common and emerging autoimmune diseases Rebekah Westermeyer Chapter 12: Endocrine and metabolic diseases with dermatologic manifestations Katherine Doerr Chapter 13: Medical management of acute and chronic otitis Dawn Logas Chapter 14: What is the difference between brand name, generic, and compounded drugs? Mark G. Papich Chapter 15: Topical therapies Dawn Logas Chapter 16: Antibiotic resistance Leah D. Blondeau and Joseph M. Blondeau Chapter 17: Omega-3 fatty acids: What’s new? Dawn Logas Chapter 18: Immunopharmacology Domenico Santoro and Megan Boyd Chapter 19: Allergen-specific immunotherapy Natalie Gedon and Ralf Mueller Chapter 20: Biologic therapies for dermatologic use Valerie Fadok Chapter 21: Use of lasers in dermatology Jason B. Pieper Chapter 22: Unconventional and plant-based therapies Dawn Logas Chapter 23: Sedation, anesthesia, and pain management in small animal dermatology Luisito S. Pablo Chapter 24: How your nursing staff can improve efficiency and compliance in the management of dermatologic cases Judy Lethbridge Chapter 25: Communication between the client, primary care practitioner, and dermatologist JoAnn Stewart Chapter 26: The future of technology and computers in veterinary medicine Ceara Byrne and Jacob Logas Index

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Book SynopsisImplement an effective and efficient inventory management system in your veterinary practice using this practical and concrete guidance Inventory Management for Veterinary Professionals provides a thorough introduction to the logistics of effective and efficient veterinary inventory management. Designed for any employee of a veterinary practice, the book covers strategies and tactics for all major aspects of inventory management. It provides veterinary professionals with a practical roadmap for this key business operation, with stories drawing on the author's experience to provide a real-world perspective. Emphasizing both the how' and the why' of developing effective inventory management systems, it's an indispensable tool for veterinary professionals at every level of practice. Taking a holistic approach to setting up, maintaining, and optimizing an inventory system, the book begins by describing the theory and strategies for inventory management, then discusses how to incorporate this knowledge into practice. Inventory Management for Veterinary Professionals offers: Detailed discussion of topics including the flow of inventory through the practice, forecasting, ordering, troubleshooting, and moreAdvice on how to receive and restock, organize, price, and sell inventoryGuidance on how to set up an inventory action planA chapter on setting and executing inventory management protocols around controlled substancesA companion website with additional tools, resources, and self-assessment questions Inventory Management for Veterinary Professionals is ideal for any veterinary professional, including practice managers, receptionists, assistants, technicians, and practice owners.

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Book SynopsisCanine Internal Medicine A thorough yet concise guide to diagnosing and managing canine medical conditions The newly revised Fourth Edition of Notes on Canine Internal Medicine delivers a comprehensive guide to the diagnosis of common and uncommon medical conditions in dogs. Written to act as a practical and fast-access subject reference for veterinary practitioners and students, Notes on Canine Internal Medicine encourages physicians to take a logical and evidence-based approach to canine medicine. Divided into five sections, the first four are dedicated to clinical presentations, physical and laboratory abnormalities, and new to this edition imaging patterns. It concludes with a section on the organ systems of canines, providing a robust summary of how to diagnose and manage common specific conditions of each system. This new edition includes: A thorough introduction to the clinical presentations of a variety of presenting complaints, with both common and uncommon causes of each complaint and a logical diagnostic approachIn-depth examinations of common and uncommon physical problems, with a complete diagnostic approach including lab results and key imaging findings that aid in diagnosisComprehensive explorations of laboratory abnormalities in haematology, serum biochemistry, and urinalysisPractical discussions of diagnostic imaging patterns, including plain radiographic, ultrasonographic, contrast radiographic, and cross-sectional imaging Notes on Canine Internal Medicine Fourth Edition is designed to be a useful resource for all veterinary clinicians; as a handy point of reference for veterinary students, recently graduated veterinary surgeons and those returning to work after career breaks, but also for experienced veterinary surgeons dealing with particularly difficult or challenging cases.Table of ContentsPreface xvii Acknowledgements xix Using this book xxi Commonly used abbreviations xxii Section 1 Presenting Complaints 1 1.1 Abortion 3 1.2 Alopecia 4 1.3 Altered behaviour 7 1.4 Altered consciousness 10 1.5 Anorexia/hyporexia/inappetence 12 1.6 Anosmia 14 1.7 Anuria/oliguria 15 1.8 Ataxia 17 1.9 Bleeding 19 1.10 Blindness 21 1.11 Constipation 23 1.12 Corneal opacity 25 1.13 Coughing 26 1.14 Deafness 29 1.15 Diarrhoea 30 1.15.1 Acute diarrhoea 31 1.15.2 Chronic diarrhoea 34 1.16 Drooling 38 1.17 Dysphagia 39 1.18 Dyspnoea/tachypnoea 41 1.19 Dysuria 44 1.20 Dystocia 46 1.21 Epistaxis 48 1.22 Exercise intolerance 49 1.23 Faecal incontinence 51 1.24 Flatulence/borborygmi 52 1.25 Haematemesis 54 1.26 Haematochezia 55 1.27 Haematuria and discoloured urine 57 1.28 Haemoptysis 60 1.29 Halitosis 61 1.30 Head tilt 62 1.31 Melaena 64 1.32 Nasal discharge 66 1.33 Nystagmus 67 1.34 Paresis/paralysis 69 1.35 Perinatal death 70 1.36 Polyphagia 72 1.37 Polyuria/polydipsia (PU/PD) 73 1.38 Preputial discharge 77 1.39 Pruritus 78 1.40 Red eye (and pink eye) 80 1.41 Regurgitation 81 1.42 Seizures 84 1.43 Sneezing 86 1.44 Stiffness, joint swelling and generalised lameness 87 1.45 Stunting 89 1.46 Tenesmus and dyschezia 91 1.47 Tremors 92 1.48 Urinary incontinence 94 1.49 Vomiting 96 1.50 Vulval discharge 98 1.51 Weakness, collapse and syncope 100 1.52 Weight gain/obesity 104 1.53 Weight loss 105 Section 2 Physical Abnormalities 109 2.1 Abdominal enlargement 111 2.2 Abdominal masses 113 2.3 Abnormal lung sounds 115 2.4 Arrhythmias 118 2.5 Ascites 121 2.6 Cyanosis 124 2.7 Eye lesions 126 2.8 Hepatomegaly 129 2.9 Horner’s syndrome 131 2.10 Hypertension 133 2.11 Hypotension 134 2.12 Hypothermia 135 2.13 Icterus/jaundice 136 2.14 Lymphadenopathy 139 2.15 Murmur 140 2.16 Oral masses 141 2.17 Pain 142 2.17.1 Abdominal pain 142 2.17.2 Generalised pain 146 2.18 Pallor 147 2.19 Perineal lesions 148 2.20 Peripheral oedema 149 2.21 Pleural effusion 151 2.22 Pneumothorax 154 2.23 Prostatomegaly 154 2.24 Pulse abnormalities156 2.25 Pyrexia and hyperthermia 158 2.26 Skin lesions 160 2.27 Skin pigmentation changes 167 2.28 Splenomegaly 169 2.29 Stomatitis 171 2.30 Stridor and stertor 172 Section 3 Laboratory Abnormalities 175 3a Biochemical tests 177 3.1 Acid–base 177 3.2 Ammonia 178 3.3 Amylase and lipase 179 3.4 Azotaemia 180 3.5 Bile acids 181 3.6 Bilirubin 182 3.7 Calcium 182 3.7.1 Hypercalcaemia 182 3.7.2 Hypocalcaemia 183 3.8 Cardiac biomarkers 184 3.8.1 N- terminal pro B-type natriuretic peptide (NT-proBNP) 184 3.8.2 Troponin I 185 3.9 Chloride 186 3.9.1 Hyperchloraemia 186 3.9.2 Hypochloraemia 186 3.10 Cobalamin 187 3.11 Cortisol (basal) 188 3.12 Creatine kinase 189 3.13 Creatinine 189 3.14 C- reactive protein (CRP)190 3.15 Folate 191 3.16 Fructosamine 191 3.17 Glucose 192 3.17.1 Hyperglycaemia 192 3.17.2 Hypoglycaemia 193 3.18 Iron profile 194 3.19 Lipids 195 3.19.1 Hyperlipidaemia and hypercholesterolaemia 195 3.19.2 Hypocholesterolaemia 196 3.20 Liver enzymes 196 3.20.1 Hepatocellular marker enzymes 196 3.20.1A Alanine aminotransferase (ALT)197 3.20.1B Aspartate aminotransferase (AST)197 3.20.1C Other hepatocellular enzymes 197 3.20.2 Cholestatic marker enzymes 197 3.20.2A Alkaline phosphatase (ALP or ALKP)198 3.20.2B Gamma- glutamyl transferase (GGT)198 3.21 Pancreatic lipase (cPL)198 3.22 Phosphate 199 3.22.1 Hyperphosphataemia 199 3.22.2 Hypophosphataemia 200 3.23 Potassium 200 3.23.1 Hyperkalaemia 200 3.23.2 Hypokalaemia 201 3.24 Sodium 202 3.24.1 Hypernatraemia 202 3.24.2 Hyponatraemia 202 3.25 Symmetric dimethylarginine (SDMA)203 3.26 Thyroid hormone 204 3.27 Total protein (albumin and globulin) 206 3.27.1 Hyperproteinaemia 206 3.27.1A Hyperalbuminaemia 206 3.27.1B Hyperglobulinaemia 206 3.27.2 Hypoproteinaemia 207 3.27.2A Hypoalbuminaemia 207 3.27.2B Hypoglobulinaemia 207 3.28 Trypsin- like immunoreactivity (TLI)208 3.29 Urea 208 3b Haematology 210 3.30 Red blood cells (RBCs)210 3.30.1 Anaemia 210 3.30.2 Erythrocytosis 213 3.31 Platelets 214 3.31.1 Thrombocytopenia 214 3.31.2 Thrombocytosis 215 3.32 White blood cells (WBCs)216 3.32.1 Leukocytosis 216 3.32.2 Leukopenia 217 3.33 Pancytopenia 218 3c Urinalysis 219 3.34 Biochemical analysis 219 3.34.1 Protein 219 3.34.2 Bilirubin 219 3.34.3 Glucose 219 3.34.4 Haem 220 3.34.5 Ketones 220 3.35 Sediment 220 3.35.1 Red blood cells 220 3.35.2 White blood cells 220 3.35.3 Epithelial cells 221 3.35.4 Crystals 221 3.35.5 Tubular casts 221 3.35.6 Waxy cast 221 3.36 Urine protein: creatinine (UPC) ratio 221 3.37 Urine specific gravity (USG)222 Section 4 Imaging Patterns 223 4.1 Abdomen 225 4.1.1 Radiography 225 4.1.1A Abdominal enlargement and mass(es) 225 4.1.1b Calcification (bone/mineral density) 225 4.1.1c Extra- intestinal gas 228 4.1.1D Gas dilation of GI tract229 4.1.1e Loss of contrast/peritoneal detail/serosal detail 230 4.1.1f Metal densities 230 4.1.1G Organ displacement 231 4.1.1H Organomegaly or change in shape 231 4.1.2 Ultrasound 232 4.1.2A Free abdominal fluid 232 4.1.2b Lymphadenopathy – mesenteric/inguinal/sublumbar 232 4.2 Bone 234 4.2.1 Bone deformities 234 4.2.2 Bone density changes 234 4.2.2A Decreased bone density (osteopenia) 234 4.2.2b Increased bone density 235 4.2.3 Bone lucencies and proliferative lesions 236 4.3 Thorax 239 4.3.1 Alveolar pattern 239 4.3.2 Bronchial pattern 239 4.3.3 Changes in cardiac outline and pulmonary vasculature 240 4.3.4 Interstitial pattern 244 4.3.5 Loss of detail 245 Section 5 Organ Systems 247 5.1 Alimentary system 249 5.1.1 Oropharynx 252 5.1.1A Craniomandibular osteopathy 252 5.1.1b Cricopharyneal achalasia 253 5.1.1C Masticatory myositis 253 5.1.1D Oral neoplasia 254 5.1.1e Stomatitis 255 5.1.2 Salivary glands 255 5.1.2A Hypersialosis/salivary gland infarction/sialoadenitis 256 5.1.3 Oesophagus 256 5.1.3A Foreign body 257 5.1.3b Megaoesophagus (MO) 258 5.1.3C Oesophagitis 261 5.1.3D Sliding hiatal hernia 262 5.1.3e Stricture 263 5.1.4 Stomach 264 5.1.4A Acute gastritis 265 5.1.4b Chronic gastritis 267 5.1.4C Gastric carcinoma 268 5.1.4D Gastric dilatation-volvulus (GDV) 269 5.1.4e Delayed gastric emptying 270 5.1.4f Gastric ulcer 272 5.1.5 Small intestine 273 5.1.5.1 Acute small intestinal diseases 274 5.1.5.1A Acute enteritis 275 5.1.5.1b Acute haemorrhagic diarrhoea syndrome (AHDS)/ haemorrhagic gastroenteritis (HGE) 276 5.1.5.1C Bacterial enteritis 277 5.1.5.1D Parvovirosis 278 5.1.5.1e Small intestinal obstruction 280 5.1.5.2 Chronic small intestinal diseases 281 5.1.5.2A Alimentary lymphoma (AL) 282 5.1.5.2b Antibiotic-responsive diarrhoea (ARD) 283 5.1.5.2C Chronic inflammatory enteropathy (CIE) 285 5.1.5.2D Dietary sensitivity 287 5.1.5.2e Intestinal parasitism 288 5.1.5.2f Intestinal protozoal infections 291 5.1.5.2G Lymphangiectasia 292 5.1.6 Large intestine 293 5.1.6A Acute colitis 294 5.1.6b Chronic colitis 295 5.1.6C Constipation 297 5.1.6D Granulomatous (histiocytic ulcerative) colitis 298 5.1.6e Large intestinal neoplasia 298 5.1.7 Pancreas 299 5.1.7A Acute pancreatitis 300 5.1.7b Chronic pancreatitis 302 5.1.7C Exocrine pancreatic insufficiency (EPI) 303 5.2 Cardiovascular system 305 5.2.1 Acquired cardiac diseases 310 5.2.1A Arrhythmogenic right ventricular cardiomyopathy (ARVC) 310 5.2.1b Dilated cardiomyopathy (DCM) 311 5.2.1C Heartworm disease/dirofilariasis 314 5.2.1D Myxomatous mitral valve disease 316 5.2.2 Congenital cardiac diseases 318 5.2.2A Aortic stenosis 318 5.2.2b Mitral valve dysplasia 319 5.2.2C Patent ductus arteriosus 321 5.2.2D Pulmonic stenosis 322 5.2.2e Tetralogy of fallot 324 5.2.2f Tricuspid dysplasia 325 5.2.2G Ventricular septal defect 326 5.2.3 Congestive heart failure (CHF) 328 5.2.3A Left-sided congestive heart failure 330 5.2.3b Right-sided congestive heart failure 331 5.2.4 Arrhythmias 332 5.2.4.1 Bradyarrhythmias 333 5.2.4.1A Atrial standstill 333 5.2.4.1b Atrioventricular (AV) block 333 5.2.4.1C Sinus bradycardia 336 5.2.4.1D Sinus arrest 336 5.2.4.1e Sick sinus syndrome 336 5.2.4.2 Tachyarrhythmias 337 5.2.4.2A Sinus tachycardia 337 5.2.4.2b Supraventricular tachyarrhythmias 338 5.2.4.2C Ventricular tachyarrhythmias 340 5.2.5 Pericardial diseases 343 5.2.5.A Pericardial effusion 343 5.2.5.B Peritoneal pericardial diaphragmatic hernia (PPDH) 346 5.3 Endocrine system 347 5.3.1 Diabetes insipidus (DI) 347 5.3.2 Diabetes mellitus (DM) 350 5.3.3 Growth hormone disorders 354 5.3.3A Acromegaly (hypersomatotropism) 354 5.3.3b Pituitary dwarfism 355 5.3.4 Adrenal gland disorders 356 5.3.4A Hyperadrenocorticism (HAC) 356 5.3.4b Hypoadrenocorticism (Addison’s disease) 360 5.3.5 Hypothyroidism 364 5.3.6 Insulinoma 367 5.3.7 Parathyroid diseases 368 5.3.7A Primary hyperparathyroidism (PHPT) 368 5.3.7b Hypoparathyroidism 369 5.4 Haemopoietic system 371 5.4.1 Anaemia of chronic kidney disease (CKD) 371 5.4.2 Immune-mediated haemolytic anaemia (IMHA) 373 5.4.3 Iron-deficiency anaemia 377 5.4.4 Lymphoid leukaemia 378 5.4.5 Other haemopoietic neoplasms 379 5.4.6 Leukopenia 380 5.4.7 Thrombosis 380 5.5 Haemostatic system 383 5.5.1 Anticoagulant rodenticide poisoning 386 5.5.2 Disseminated intravascular coagulation (DIC) 388 5.5.3 Factor VIII deficiency (haemophilia A) 390 5.5.4 Hyperfibrinolysis 391 5.5.5 Immune-mediated thrombocytopenia (IMTP) 392 5.5.6 von Willebrand disease 393 5.5.7 Vasculitis 395 5.6 Hepatobiliary system 397 5.6.1 Chronic hepatitis (CH)/cirrhosis 399 5.6.2 Cholangitis/cholangiohepatitis 400 5.6.3 Cholecystitis 401 5.6.4 Congenital porto-systemic shunt (PSS) 402 5.6.5 Copper-associated chronic hepatitis 404 5.6.6 Extra-hepatic bile duct obstruction (EHBDO) 404 5.6.7 Gall bladder mucocoele 405 5.6.8 Hepatic neoplasia 407 5.6.9 Infectious canine hepatitis 408 5.6.10 Nodular hyperplasia 408 5.6.11 Portal vein hypoplasia (PVH) 409 5.6.11A Microvascular dysplasia (MVD) 409 5.6.11b Non-cirrhotic portal hypertension/juvenile hepatic fibrosis 410 5.6.12 Steroid hepatopathy 410 5.6.13 Vacuolar/reactive hepatopathy 411 5.7 Immune system 413 5.7.1 (Auto)immune-mediated disorders 414 5.7.1.1 Immune-mediated polyarthritis (IMPA) 414 5.7.1.2 Immunodeficiency 415 5.7.1.2A Canine leukocyte adhesion deficiency (CLAD) 416 5.7.1.2B Cyclic haematopoiesis (cyclic neutropenia) 416 5.7.1.2C Hereditary selective cobalamin malabsorption (Imerslund-Gräsbeck syndrome) 417 5.7.1.2D Immunoglobulin deficiency 417 5.7.1.2E Trapped neutrophil syndrome 418 5.7.1.3 Lymphadenitis 418 5.7.1.4 Systemic lupus erythematosus (SLE) 420 5.7.2 Neoplasia of immune cells 420 5.7.2.1 Lymphoma 420 5.7.2.2 Mast cell tumour (MCT) 422 5.7.2.3 Multiple myeloma 424 5.7.2.4 Thymoma 424 5.8 Neurological system 427 5.8.1 Cerebrovascular disease 429 5.8.2 Corticosteroid-responsive tremor syndrome 430 5.8.3 Hydrocephalus 431 5.8.4 Idiopathic epilepsy 431 5.8.5 Idiopathic head tremor 433 5.8.6 Idiopathic vestibular disease 434 5.8.7 Infectious diseases affecting the nervous system 435 5.8.8 Movement disorders 436 5.8.9 Meningoencephalitis of unknown origin (MUO) 437 5.8.10 Myasthenia gravis (MG) 438 5.8.11 Neoplasia of the neurological system 439 5.8.12 Polyradiculoneuritis 441 5.8.13 Steroid-responsive meningitis-arteritis (SRMA) 442 5.9 Reproductive system 445 5.9.1 Mammary gland disease 445 5.9.1a Mastitis 446 5.9.1b Mammary neoplasia 446 5.9.2 Ovarian remnant syndrome 447 5.9.3 Prostatic disease 448 5.9.4 Pseudocyesis (false pregnancy) 449 5.9.5 Pyometra 450 5.9.6 Testicular neoplasia 451 5.9.7 Vaginitis 452 5.10 Respiratory system 455 5.10.1 Nasal disorders 457 5.10.1A Chronic idiopathic rhinitis 457 5.10.1b Sinonasal aspergillosis (fungal rhinitis) 458 5.10.2 Upper-airway disorders 459 5.10.2A Brachycephalic obstructive airway syndrome (BOAS) 459 5.10.2b Infectious tracheobronchitis 460 5.10.2C Laryngeal paralysis 461 5.10.2D Tracheal collapse 462 5.10.2e Tracheobronchial foreign body 464 5.10.3 Lower-airway disorders 464 5.10.3A Chronic bronchitis 465 5.10.3b Eosinophilic bronchopneumopathy 465 5.10.3C Lungworm (Angiostronglylus vasorum)466 5.10.4 Pulmonary parenchymal disease 468 5.10.4A Pneumonia 468 5.10.4b Non-cardiogenic pulmonary oedema 469 5.10.4C Pulmonary fibrosis 470 5.10.4D Pulmonary neoplasia 471 5.10.5 Pleural space disease 473 5.10.5A Idiopathic chylothorax 473 5.10.5b Pneumothorax 474 5.10.5C Pyothorax 475 5.11 Systemic infections 477 5.11.1 Anaplasmosis 479 5.11.2 Babesiosis 480 5.11.3 Borreliosis (Lyme Disease) 481 5.11.4 Brucellosis 482 5.11.5 Distemper 484 5.11.6 Ehrlichiosis 485 5.11.7 Hepatozoonosis 486 5.11.8 Leishmaniosis 487 5.11.9 Leptospirosis 489 5.11.10 Neosporosis 491 5.11.11 Rabies 492 5.11.12 Toxoplasmosis 493 5.12 Urinary system 495 5.12.1 Kidney diseases 495 5.12.1A Acute kidney injury 497 5.12.1b Chronic kidney disease 499 5.12.1C Glomerular disorders 501 5.12.1D Pyelonephritis 503 5.12.1e Renal tubular disorders 504 5.12.2 Lower urinary tract diseases 506 5.12.2A Functional disorders of urination 507 5.12.2b Neoplasia of the urinary system 508 5.12.2C Urethritis 509 5.12.2D Urinary tract infection (UTI) 510 5.12.2e Urolithiasis 511 Abbreviations 513 Index 519

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Book SynopsisPATHOGENESIS OF BACTERIAL INFECTIONS IN ANIMALS Comprehensive review of the major bacterial pathogens of animals, focusing on the current understanding of how they cause disease Pathogenesis of Bacterial Infections in Animals, Fifth Edition is a specialist reference that provides a comprehensive review of bacterial pathogens in animals and their complex interplay with disease processes, offering a complete understanding of how bacteria cause disease in animals. It covers the many recent advances in the field including the newest taxonomies. In this revised and long anticipated fifth edition, additional introductory chapters have been added to set the material in context, and more figures added to integrate and improve understanding and comprehension throughout the text. A companion website presents the figures from the book in PowerPoint and references. This detailed reference includes novel approaches to controlling bacterial pathogens in the light of growing concerns about antimicTrade Review"The book is well-produced and a useful update on bacterial pathogenesis from a genomics standpoint. It belongs in the diagnostic laboratory, and not just on the bacteriologist’s shelf." - Journal of Veterinary Diagnostic Investigation, 2023, Vol. 35(2) 217–218Table of ContentsPreface xv List of Contributors xvii About the Companion Website xxv 1 Themes in Bacterial Pathogenesis 1John F. Prescott Introduction 1 The Basic Elements of Bacterial Pathogenesis 1 Concepts of Bacterial Virulence are Being Refined 5 Host–Pathogen Communications are Critical 9 Pathogenesis in the Post-Genomic Era 11 Gaps in Knowledge and Anticipated Directions 13 References 13 2 Evolution of Bacterial Pathogens 15Patrick Boerlin What are Pathogens and How Do They Emerge? 15 Bacterial Fitness and Virulence 17 Sources of Genetic Diversity, Population Structure, and Genome Plasticity 18 Pathogenicity Islands 20 Bacteriophages and Their Role in Pathogen Evolution and Virulence 22 Examples of Virulence Evolution 23 Gaps in Knowledge and Anticipated Directions 27 References 28 3 Understanding Pathogenesis Through Pathogenomics and Bioinformatics 32Gregorio Iraola and John D. Boyce Introduction 32 How Mutations Generate Bacterial Diversity 34 Genome Sequencing Technologies 36 Genome Assembly 38 Gene Prediction and Annotation 39 Defining Prokaryotic Species from Genomes 41 The Pangenome Concept, Reconstruction, and Comparative Analyses 41 Phylogenomics and Genome-Wide Association Studies 42 Functional Genomics for Understanding Host–Pathogen Interactions 44 Reverse Vaccinology 48 Gaps in Knowledge and Anticipated Directions 51 References 52 4 Experimental Approaches to Understanding Pathogenesis 57Francesca L. Short and Janet I. MacInnes Introduction 57 Testing Koch’s Postulates 57 Virulence Factors and Main Steps in Pathogenesis 58 Molecular Koch’s Postulates 60 Refining Animal Usage 60 Experimental Approaches for Virulence Factor Discovery and Validation 62 Approaches for Virulence Factor Discovery 63 Gene Disruption Approaches for Virulence Factor Discovery 71 Bringing It All Together: Validation and Further Characterization of Virulence Factors 73 Two Stories of Virulence Factor Discovery and Characterization: Pasteurella multocida Capsule, and Mycoplasma bovis Adhesins 74 Gaps in Knowledge and Anticipated Directions 75 References 76 5 Subversion of the Immune Response by Bacterial Pathogens 79Douglas C. Hodgins, Raveendra R. Kulkarni, and Patricia E. Shewen Introduction 79 Subversion of Innate Responses 80 Subversion of Adaptive Immunity 85 Manipulation of Cell Fate 88 Non-Coding RNA and Host-Pathogen Interactions 91 Epigenetic and Genetic Modulation 92 Gaps in Knowledge and Anticipated Directions 94 References 94 6 Chinks in the Armor 99Allison C. Leonard, Celine Stoica, and Georgina Cox Introduction 99 Virulence Factors: Pathogenesis-Based Targets to Combat Bacterial Pathogens 99 Targeting Bacterial Host Cell Adhesion and Biofilm Formation 100 Quorum Sensing Inhibition 104 Interfering with Two-Component Regulatory Systems 105 Inhibiting Bacterial Motility 106 Toxin Neutralization 107 Inhibitors of Bacterial Secretion Systems 107 Targeting Nutrient Acquisition: Starving the Pathogen 110 Antivirulence Phage Therapy 111 Bacterial Drug Efflux Pumps as Pathogenesis-Based Antibacterial Targets 112 Gaps in Knowledge and Anticipated Directions 112 References 113 7 Escherichia coli 117John M. Fairbrother and Carlton L. Gyles Introduction 117 Pathotypes of E. coli and Associated Disease and Pathological Changes in Animals 119 Virulence Factors of Pathogenic E. coli 126 Pathogenesis of Enterotoxigenic E. coli 141 Pathogenesis of Enteropathogenic E. coli Disease 144 Pathogenesis of Shiga Toxin-Producing E. coli Disease 146 Pathogenesis of Extraintestinal Pathogenic E. coli Infections 149 Gaps in Knowledge and Anticipated Directions 156 References 157 8 Salmonella 162Paul A. Barrow, Michael A. Jones, Kate C. Mellor, and Nick R. Thomson Introduction 162 Characteristics of the Organism 162 Types of Disease and Pathologic Changes 167 Salmonella Infections in Different Major Farmed Animal Species 169 Virulence Factors 174 Pathogenesis 179 Immunity to Infection and its Manipulation by Salmonella 186 Antimicrobial Resistance 190 Gaps in Knowledge and Anticipated Directions 191 References 192 9 Yersinia 200Anne-Sophie Le Guern and Javier Pizarro-Cerdá Introduction 200 Characteristics of the Organism 200 Pathogenic Species 200 Taxonomy 201 Major Virulence Factors of the Highly Pathogenic Yersinia 203 Yersinia pestis 205 Yersinia pseudotuberculosis and Yersinia enterocolitica 209 Yersinia ruckeri 213 Yersinia entomophaga 213 Control of Yersinia Infections 214 Gaps in Knowledge and Anticipated Directions 214 References 215 10 Pasteurella 221Marina Harper, Thomas R. Smallman, and John D. Boyce Introduction 221 Characteristics of the Organism 221 Source of Infection: Ecology, Evolution, and Epidemiology 223 Types of Disease and Pathologic Changes 223 Virulence Factors and Pathogenomics 225 Regulation of Virulence 233 Pathogenesis 235 Immunity 236 Control 238 Gaps in Knowledge and Anticipated Directions 239 References 239 11 Mannheimia and Bibersteinia 244Jeff L. Caswell and Charles J. Czuprynski Introduction 244 Characteristics of the Organism 244 Pathogenic Species 245 Source of Infection: Ecology, Evolution, and Epidemiology 245 Types of Disease and Pathologic Changes 247 Virulence Factors and Pathogenomics 249 Regulation of Virulence 250 Pathogenesis 251 Immunity 254 Control 254 Gaps in Knowledge and Anticipated Directions 255 References 256 12 Actinobacillus 262Janine T. Bossé, Adina R. Bujold, and Lu Li Introduction 262 Actinobacillus pleuropneumoniae 262 Actinobacillus lignieresii 277 Actinobacillus equuli 278 Actinobacillus suis 279 Gaps in Knowledge and Future Directions 281 References 283 13 Other Pasteurellaceae: Avibacterium, Bibersteinia, Gallibacterium, Glaesserella, and Histophilus 290Anders M. Bojesen, Virginia Aragon, and Pat J. Blackall Introduction 290 Avibacterium 290 Bibersteinia 292 Gallibacterium 295 Glaesserella parasuis 301 Histophilus 309 References 311 14 Pseudomonas 318Erin L. Westman, Véronique L. Taylor, and Joseph S. Lam Introduction 318 Characteristics of the Organism 318 Pathogenic Species 319 Sources of Infection: Ecology, Evolution, and Epidemiology 320 Types of Disease and Pathologic Changes 320 Virulence Factors and Pathogenomics 321 Pathogenesis 328 Immunity 330 Control, Prevention, and Treatment 331 Gaps in Knowledge and Anticipated Directions 335 References 337 15 Moraxella 344John A. Angelos Introduction 344 Infectious Bovine Keratoconjunctivitis 344 Pathogenesis of Moraxella bovis Infection 346 Immunity 352 Control 354 Gaps in Knowledge and Future Directions 354 References 355 16 Brucella 361Clayton C. Caswell, Angela Arenas-Gamboa, and Jeff T. Foster Introduction 361 Characteristics of the Organism 361 Pathogenic Species 362 Source of Infection: Ecology, Evolution, and Epidemiology 362 Types of Disease and Pathologic Changes 363 Virulence Factors 366 Regulation of Virulence 368 Pathogenomics 369 Pathogenesis 370 Immunity 370 Control 371 Gaps in Knowledge and Anticipated Directions 371 References 372 17 Bordetella 376Colleen J. Sedney, Tracy L. Nicholson, and Eric T. Harvill Introduction 376 Characteristics of the Organisms 376 Pathogenic Species 377 Source of Infection: Ecology and Epidemiology 379 Types of Disease and Pathologic Changes 380 Virulence Factors 380 Regulation of Virulence 385 Pathogenesis 385 Immunity 385 Control 387 Gaps in Knowledge and Anticipated Directions 389 References 389 18 Campylobacter 393Zuowei Wu, Orhan Sahin, and Qijing Zhang Introduction 393 Diseases, Etiology, and Ecology 394 Clinical Observations and Pathologic Changes 397 Pathogenesis and Virulence Factors 398 Pathogenomics and Evolution 402 Immunity 405 Control 406 Gaps in Knowledge and Future Directions 407 References 408 19 Helicobacter 413Chloë De Witte, Helena Berlamont, and Freddy Haesebrouck Introduction 413 Gastric Helicobacters 413 Enterohepatic Helicobacters 425 Gaps in Knowledge and Future Directions 426 References 427 20 Chlamydia and Coxiella 433Martina Jelocnik, Wilhelmina M. Huston, and Hayley J. Newton Introduction 433 Chlamydiae 433 Characteristics of the Organism 433 Source of Infection: Ecology, Evolution and Epidemiology 436 Types of Disease and Pathologic Changes 436 Pathogenesis 442 Immunity and Control 442 Gaps in Knowledge and Anticipated Directions 443 Coxiella burnetii 443 Characteristics of the Organism 444 Source of Infection: Ecology, Evolution and Epidemiology 445 Types of Disease and Pathologic Changes 445 Virulence Factors and Pathogenomics 447 Immunity and Control 448 Gaps in Knowledge and Anticipated Directions 449 References 449 21 Rickettsiales 456Jere W. McBride, Roman R. Ganta, and David H. Walker Introduction 456 Family Anaplasmataceae 457 Anaplasma Species 457 Ehrlichia Species 463 Neorickettsia Species 474 Family Rickettsiaceae 476 Rickettsia Species 476 References 480 22 Lawsonia intracellularis 486Roberto M. C. Guedes, Fabio A. Vannucci, and Connie J. Gebhart Introduction 486 Characteristics of the Organism 486 Sources of Infection: Ecology and Epidemiology 489 Types of Disease and Pathologic Changes 490 Virulence Factors and Pathogenomics 491 Pathogenesis 492 Immunity 496 Control 497 Gaps in Knowledge and Anticipated Directions 497 References 498 23 Leptospira 502Cyrille Goarant, Ben Adler, and Alejandro de la Peña Moctezuma Introduction 502 Characteristics of the Organism 502 Leptospira Species 505 Source of Infection: Ecology, Evolution, and Epidemiology 505 Clinical Presentation and Signs 511 Virulence Factors and Pathogenomics 511 Regulation of Virulence 514 Pathogenesis 514 Immunity 516 Control 518 Gaps in Knowledge and Anticipated Directions 518 References 519 24 Brachyspira 528Joseph E. Rubin and Judith Rohde Introduction 528 Characteristics of the Organism 528 Pathogenic Species and Disease Associations 529 Source of Infection: Ecology, Evolution, and Epidemiology 530 Virulence Factors and Pathogenomics 531 Pathogenesis 531 Immunity 537 Control 538 Gaps in Knowledge and Anticipated Directions 538 References 539 25 Staphylococcus 543Amy C. Pickering, Andreas F. Haag, José R. Penades, and J. Ross Fitzgerald Introduction 543 Characteristics of the Organism 543 Pathogenic Species 544 Staphylococcus aureus Infections in Cattle 546 Staphylococcus aureus Infections in Poultry 551 Staphylococcus aureus Infections in Rabbits 553 Staphylococcus hyicus Infections in Pigs 554 Staphylococcus pseudintermedius Infections in Dogs 556 Gaps in Knowledge and Future Directions 559 References 560 26 Streptococcus 565John F. Timoney Introduction 565 Characteristics of the Organism 565 Pathogenic Species 565 Streptococcus agalactiae 567 Streptococcus dysgalactiae 569 Streptococcus uberis 570 Streptococcus equi 571 Streptococcus zooepidemicus 577 Streptococcus canis 579 Streptococcus suis 580 Gaps in Knowledge and Anticipated Directions 583 References 583 27 Bacillus anthracis 588Joachim Frey Introduction 588 Characteristics of the Organism: Taxonomy and Phylogeny 588 Source and Spread of the Infection: Ecology, Evolution, and Epidemiology 591 Types of Disease and Pathologic Changes 592 Virulence Factors and Pathogenomics 594 Regulation of Virulence 595 Pathogenesis 596 Immunity and Vaccines 598 Control and Prevention of Anthrax 598 Gaps in Knowledge and Anticipated Directions 600 References 601 28 Enteric Clostridia 607Evelien Dierick, Evy Goossens, John F. Prescott, Richard Ducatelle, and Filip Van Immerseel Introduction 607 Clostridium perfringens 607 Characteristics of the Organism 607 Pathogenic Types 608 Sources of Infections: Ecology, Evolution and Epidemiology 608 Types of Disease and Pathologic Changes 611 Virulence Factors 616 Regulation of Virulence 622 The Pathogenesis of Clostridium perfringens Enteric Disease 622 Control 625 Gaps in Knowledge and Anticipated Directions 625 Clostridioides difficile 626 Characteristics of the Organism 626 Source of Infection: Ecology, Evolution and Epidemiology 626 Types of Disease and Pathologic Changes 627 Disease 627 Virulence Factors and Pathogenomics 627 Regulation of Virulence 628 Pathogenesis 629 Immunity 630 Control 630 Gaps in Knowledge and Anticipated Directions 630 Other Enteric Clostridia 630 References 631 29 Histotoxic Clostridia 635Andrew N. Rycroft Introduction 635 Characteristics of the Organisms 635 Source of Infection and Basic Pathogenesis 636 Pathogenic Species 636 Clostridium septicum (Malignant Edema/Gas Gangrene) 638 Clostridium chauvoei (Blackleg) 639 Paeniclostridium sordellii 640 Clostridium novyi Type B (Black Disease/Bighead) 642 Clostridium haemolyticum 643 Clostridium perfringens 644 Control 645 Gaps in Knowledge and Future Directions 645 References 646 30 Neurotoxic Clostridia 648Michel R. Popoff Introduction 648 Characteristic of the Organisms 648 Clostridium botulinum 648 Clostridium tetani 650 Sources of Infection: Ecology and Epidemiology 652 Diseases 656 Botulism 656 Tetanus 657 Virulence Factors 658 Pathogenesis 659 Control 663 References 664 31 Mycoplasmas 667Pollob K. Shil, Nadeeka K. Wawegama, Glenn F. Browning, Amir H. Noormohammadi, and Marc S. Marenda Introduction 667 Characteristics of the Organisms 667 Pathogenic Species 668 Source of Infection: Ecology, Evolution, and Epidemiology 668 Virulence Factors and Pathogenomics 670 Regulation of Virulence 674 Types of Disease and Pathologic Changes 674 Pathogenesis 680 Immunity 688 Control 690 Gaps in Knowledge and Anticipated Directions 690 References 691 32 Corynebacterium, Arcanobacterium, and Trueperella 701Thiago D. Barral, Ricardo W. Portela, Núbia Seyffert, and Robert J. Moore Corynebacterium 701 Corynebacterium pseudotuberculosis 701 Bovine Pyelonephritis Caused by Corynebacterium Species 706 Other Animal Pathogenic Corynebacterium Species 706 Arcanobacterium 707 Trueperella 709 Gaps in Knowledge and Future Directions 710 References 710 33 Rhodococcus equi 715José A. Vázquez-Boland, Macarena G. Sanz, and John F. Prescott Introduction 715 Characteristics of the Organism 715 Source of Infection and Epidemiology 717 Types of Disease and Pathologic Changes 720 Virulence Factors 721 Evolution of Rhodococcus equi Virulence 723 Pathogenesis 724 Immunity 726 Treatment and Control 728 Gaps in Knowledge and Anticipated Directions 730 References 731 34 Mycobacterium 736Karren M. Plain, Karen Stevenson, Richard J. Whittington, and Nathalie Winter Introduction 736 Characteristics of the Organism 736 Sources of Infection 738 Source of Infection: Evolution and Epidemiology 739 Virulence Factors and Pathogenomics 740 Regulation of Virulence 742 Types of Disease 743 Pathogenesis 744 Adaptive Immunity and Mycobacterial Pathogenesis 748 Control 750 Gaps in Knowledge and Anticipated Directions 750 References 752 35 Gram-Negative Anaerobes 757John F. Prescott Introduction 757 General Bacterial Pathogenesis Aspects 757 Fusobacterium 759 Bacteroides 763 Prevotella and Porphyromonas 764 Dichelobacter nodosus 765 Treponema 767 Gaps in Knowledge and Anticipated Developments 768 References 768 Index 773

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Book SynopsisInterpretation of the Electrocardiogram in Small Animals Explore this easy-to-follow clinical manual on how to interpret electrocardiograms in canine and feline patientsInterpretation of the Electrocardiogram in Small Animals delivers a simplified and accessible approach to electrocardiography interpretation for veterinarians treating dogs and cats. This practical manual covers a comprehensive list of arrhythmias and associated phenomena using an easy-to-follow format, with hundreds of electrocardiograms and ladder diagrams supporting the text. The book focuses on the clinical applications of electrocardiographic interpretation, with less emphasis on physics and subcellular mechanisms, making the book a useful patient-side resource. Interpretation of the Electrocardiogram in Small Animals offers readers an up-to-date understanding and knowledge of common and rare phenomena alike. Beginning with a description of the single cardiac cycle as illustrated by surface EKG, the book moves Table of ContentsMain Introduction Part I: The P-QRS-T: Introduction Chapter 1 The P-QRS-T: The Basics Chapter 2 The P-QRS-T: Some Abnormalities Chapter 3 The P-QRS-T: Trouble Part II: Aberrancy: Introduction Chapter 4 Atrial Aberrancy Chapter 5 Right Bundle Branch Block 1) Left Bundle Branch Block 2) Fascicular Blocks 3) Wide Complex Supraventricular Tachycardia and Interventricular Conduction Disturbances Part III: Arrhythmias: Introduction Sinoatrial Arrhythmias: Introduction 4) Sinoatrial Bradyarrhythmias 5) Sinoatrial Block 6) Sick Sinus Syndrome 7) Sinoatrial Tachyarrhyhmias Atrial Arrhythmias: Introduction 8) Atrial Bradyarrhythmias 9) Atrial Extrasystoles 10) Atrial Tachycardia 11) Bypass-Tract Mediated Supraventricular Tachycardia 12) Atrial Flutter 13) Atrial Fibrillation Junctional Arrhythmias: Introduction 14) Junctional Bradyarrhythmias 15) Atrioventricular Block 16) Junctional Extrasystoles 17) Junctional Tachycardia Ventricular Arrhythmias: Introduction 18) Ventricular Bradyarrhythmias 19) Ventricular Extrasystoles 20) Ventricular Tachycardia, Flutter and Fibrillation Part IV: Pacemakers: Introduction 21) Pacemakers: The Basics 22) Pacemakers: Some Abnormalities 23) Pacemakers: Trouble Individual Chapter Subsections: Chapter 1 The P-QRS-T: The Basics Leads Waveforms/intervals Amplitudes Paper speeds Mean electrical axis False poling Situs Inversus Chapter 2 The P-QRS-T: Some Abnormalities P pulmonale/right atrial abnormality P pseudo-pulmonale P mitrale/left atrial abnormality Interratrial conduction defect P pseudo-mitrale P biatriale/biatrial abnormality P pseudo-biatriale Right ventricular hypertrophy/right axis deviation Left ventricular hypertrophy/left axis deviation Biventricular hypertrophy Horizontal axis Vertical axis Indeterminant axis Early repolarization Chapter 3 The P-QRS-T: Trouble P-R segment changes Q-T segment changes The prolonged QRS Hyperkalemia Hypokalemia Other changes calcium magnesium Q-Ti prolongation hypothermia Digoxin effects Cushing’s response S-T segment elevation/depression myocardial infarction/ischemic changes Low-voltage QRS Electrical alternans Pericarditis Chapter 4 Atrial Aberrancy Interatrial/Intra-atrial block Chung’s phenomenon Atrial ectopy Chapter 5 Right Bundle Branch Block Incomplete right bundle branch block Ashman’s phenomenon/2nd-in-a-row anomaly Rate-dependent and intermittent right bundle branch block Complete right bundle branch block Chapter 6 Left Bundle Branch Block Incomplete left bundle branch block Rate-dependent and intermittent left bundle branch block Complete left bundle branch block Chapter 7 Fascicular Blocks Left anterior fascicular block Left medial fascicular block Left posterior fascicular block Bilateral bundle branch block Bifascicular block Masquerading bundle branch block Trifascicular block Arborization block Chapter 8 Wide Complex Supraventricular Tachycardia and Interventricular Conduction Disturbances Wide complex supraventricular tachycardia Interventricular conduction disturbances Chapter 9 Sinoatrial Bradyarrhythmias Sinus bradycardia Sinus arrhythmia Non-phasic sinus arrhythmia Phasic sinus arrhythmia Respiratory sinus arrhythmia Wandering pacemaker Non-respiratory phasic sinus arrhythmia Ventriculophasic sinus arrhythmia Sinus bigeminy Sinoatrial escape-capture bigeminy Sinus pause Sinus arrest Asystole Chapter 10 Sinoatrial Block Type I 2nd degree sinoatrial block Type II 2nd degree sinoatrial block Chapter 11 Sick Sinus Syndrome Overdrive suppression Sinus nodal dysfunction Bradycardia variant Tachycardia-bradycardia variant Chapter 12 Sinoatrial Tachyarrhythmias Sinoatrial extrasystoles Reciprocation Parasystole Sinus tachycardia Sinus nodal reentrant tachycardia Chapter 13 Atrial Bradyarrhythmias Atrial escape beats Atrial escape-capture bigeminy Atrial escape rhythm Atrial standstill Hyperkalemia Sinoventricular rhythm Atrial muscular dystrophy Chapter 14 Atrial Extrasystoles Atrial premature complexes Right atrial premature complexes Left atrial premature complexes Multifocal atrial premature complexes Resetting Resetting with a pause Interpolation Atrial bigeminy Atrial trigeminy Atrial premature complexes with aberrancy Supernormal excitation Non-conducted atrial premature complexes Atrial fusion Reciprocation Parasystole Chapter 15 Atrial Tachycardia Accelerated atrial rhythm Automatic atrial tachycardia Interratrial reentrant tachycardia Atrial dissociation Chapter 16 Bypass-Tract Mediated Supraventricular Tachycardia Ventricular pre-excitation and accessory pathways Ventricular fusion Atrial echo Atrioventricular reentrant tachycardia Orthodromic Antidromic Chapter 17 Atrial Flutter Atrial flutter Type I atrial flutter typical reverse typical/atypical Type II atrial flutter (“true atypical”) Atrioventricular block Artifacts Chapter 18 Atrial fibrillation Atrial fibrillation Aberrancy Ashman’s phenomenon Ventricular ectopics Rule of bigeminy Atrioventricular dissociation Concealed conduction Chapter 19 Junctional Bradyarrhythmias Junctional escape beats Junctional escape-capture bigeminy Junctional escape rhythm Rule of reset Reciprocation Junctional dissociation (double junctional rhythms) Ventriculophasic junctional arrhythmia Chapter 20 Atrioventricular Block 1st degree atrioventricular block (incomplete atrioventricular block with long P-Ri) 2nd degree atrioventricular block (incomplete atrioventricular block) Type I 2nd degree atrioventricular block Low grade Typical Wenckebach periodicity Atypical Wenckebach periodicity 2:1 Wenckebach High grade Type II 2nd degree atrioventricular block Low grade 2:1 Mobitz High grade Block/acceleration dissociation Paroxysmal atrioventricular block 3rd degree atrioventricular block (complete atrioventricular block) Junctional escape Ventricular escape Atrioventricular dissociation Ventriculoatrial block Exit block Chapter 21 Junctional Extrasystoles Junctional premature complexes Resetting Resetting with a pause Interpolation Junctional bigeminy Junctional trigeminy Junctional premature complexes with aberrancy Non-conducted junctional premature complexes Concealed conduction Atrial fusion Reciprocation Parasystole Chapter 22 Junctional Tachycardia Accelerated junctional rhythm Isorhythmic dissociation Accrochage Synchrony Automatic junctional tachycardia Atrioventricular nodal reentrant tachycardia Orthodromic Antidromic Chapter 23 Ventricular Bradyarrhythmias Ventricular escape beats Ventricular escape-capture bigeminy Ventricular escape rhythm Electromechanical dissociation Asystole Chapter 24 Ventricular Extrasystoles Ventricular premature complexes Right ventricular premature complexes Left ventricular premature complexes Compensatory pause Compensatory-like pause Interpolation Post-extrasystolic aberrancy Ventricular bigeminy The Rule of bigeminy Ventricular trigeminy Ventricular quadrigeminy and pentageminy Concealed conduction (“non-conducted ventricular premature complexes”) Concealed ventricular bigeminy Concealed ventricular trigeminy Ventricular fusion Ventriculoatrial conduction and reciprocation Atrial fusion Parasystole Chapter 25 Ventricular Tachycardia, Flutter and Fibrillation Accelerated idioventricular rhythm Atrioventricular dissociation Isorhythmic dissociation Accrochage Synchrony Ventriculoatrial association and accelerated ventricular rhythm Polymorphic and bidirectional accelerated idioventricular rhythm Ventricular tachycardia Left ventricular tachycardia Fascicular ventricular tachycardia Bidirectional ventricular tachycardia Right ventricular tachycardia Right ventricular outflow tract tachycardia Bundle branch reentrant ventricular tachycardia Ventriculoatrial block Double tachycardia Polymorphic ventricular tachycardia Torsades de pointes Ventricular flutter Ventricular fibrillo-flutter/ventricular dissociation Ventricular fibrillation Chapter 26 Pacemakers: The Basics Indications Unipolar vs. bipolar Modes Endocardial/transvenous vs. epicardial leads MEA of the paced QRS Chapter 27 Pacemakers: Some Abnormalities Concealed conduction VA conduction Paced fusion complexes Paced pseudofusion complexes Paced reciprocal complexes Chapter 28 Pacemakers: Trouble Undersensing Oversensing Failure to capture Battery depletion Pacemaker-mediated tachycardia Pacemaker syndrome

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Book SynopsisDrug Compounding for Veterinary Professionals Safely, effectively, and legally tailor drug treatments to the needs of your specific veterinary patients with this accessible guide Drug Compounding for Veterinary Professionals provides an accessible, easy-to-use guide to all aspects of prescribing individualized mixtures of medications in veterinary practice. Its emphasis on practical knowledge and its discussion of both in-house and external options make it a comprehensive introduction to using compounded medications in animals. It guides practitioners through every step of the process, from formulating a compound to working with outside pharmacists. The book presents guidance on how to get more information on current regulations, consider the risks and benefits, develop formulations, and more. Drug Compounding for Veterinary Professionals readers will also find: Figures and line drawings illustrating effective compounding techniques and conceptsAn emphasis on practical knowledge for Table of ContentsForeword xi Preface xiii List of Acronyms xiv About the Companion Website xvi Introduction xvii 1 Compounding Regulations 1 Organizations and Regulatory Agencies Involved with Compounding 3 Food and Drug Administration 3 United States Pharmacopeia 3 Drug Enforcement Administration 5 State Boards of Pharmacy 6 State Veterinary Boards 6 Compliance Policy Guides and Guidance for Industry Documents 6 What Is Compounding? 7 The Food, Drug, and Cosmetic Act 9 Animal Medicinal Drug Use Clarification Act 9 Preparing Compounds from an Approved Product or a Pure Drug Powder 10 Federal Versus State Law 11 Office Use Compounding 12 Drug Quality and Security Act 13 Finding Additional Information 13 2 Risk–Benefit Analysis of Compounded Medications 17 Benefits of Compounded Products 17 Dosage Form 17 Flavoring 20 Dosage Strength 20 Eliminating Ingredients 21 Availability Issues 22 Appropriate Use of Compounded Medications 22 FDA-Approved Drugs 23 Compounded Medication Risks 25 Compounded (USP) Versus Manufactured (cGMP) 26 Risks Associated with Compounded Medications – A Look at the Literature 28 Studies Showing Incorrect Potency 28 Studies Showing Lack of Stability 31 Studies Showing Lack of Efficacy 31 Risks Associated with Specific Types of Compounds 32 Active Ingredient Source Decisions 34 Patient-Specific Compounding Versus Office Use Compounding 35 Adverse Event Reporting 36 Identifying Potential Formulation Issues 37 Drug Recalls 38 Selecting a Compounding Pharmacy 39 Client Education 40 Reducing Risk in Practice 40 Conclusion 41 3 Beyond-Use Dating 45 Factors Considered When Assigning BUDs and Expiration Dates 45 USP Default BUDs 48 Stability Studies 49 Evaluating Stability Studies 50 Determining BUDs for In-House Formulations 51 BUD Considerations When Prescribing Compounded Medications 52 Conclusion 53 4 Identifying High-Quality Compounding Pharmacies 55 Case Study 1 55 Case Study 2 58 What to Evaluate 59 General Practices 59 Staff Skill Level 61 Familiarity with Veterinary Medicine 61 Pharmacy Culture 61 Ways to Evaluate Compounding Pharmacies 62 Looking Beyond the Pharmacy’s Website 63 What to Look for on a Tour 65 Questions to Ask the Pharmacist in Charge 65 Conclusion 67 5 Formulation Development 69 Dosage Forms 69 Oral Administration 69 Oral Solutions 69 Oral Suspensions 70 Oral Syrups 70 Oral Capsules 71 Oral Tablets 72 Oral Treats 73 Oral Emulsions 73 Oral Pastes 74 Oral Powders 74 Transdermal Administration 74 Topical Administration 75 Topical Solutions 75 Topical Ointments 76 Topical Shampoos 76 Topical Mousses 76 Topical Emulsions 76 Topical Creams 77 Topical Gels 77 Otic Administration 77 Otic Solutions 77 Otic Suspensions 77 Otic Ointments 78 Other Routes of Administration 78 Rectal Solutions 78 Intranasal Solutions 78 Injectable Preparations 78 Ophthalmic Preparations 79 Ingredients 79 Ingredient Selection 79 Solubility 81 Partition Coefficient 82 Density 83 Water Activity 83 pH 83 Chelators 84 Antioxidants 84 Preservatives 84 Flavors, Coating Agents, and Sweeteners 85 Coloring Agents 87 Salt Forms 87 Organic Salts 88 Inorganic Salts 88 Common Excipients by Dosage Form 89 Oral Liquid Medications 89 Oral Solid Medications 89 Emulsions 91 Transdermal Medications 91 Cream, Gel, and Ointment Medications 91 Hazardous Drugs 92 Beyond-Use Dates 92 Formulation Resources 93 Calculations 93 Measurements Used in Compounding 96 Displacement Factor 96 Capsules: Packing Statistics 98 Packing Statistic of Drug 98 Average Weight of Ingredients 98 Percentage of Drug per Capsule Using Bulk Powder 98 Percentage of Drug per Capsule Using Manufactured Tablets 99 Percentage/Amount of Filler per Capsule 101 Conversion to Grams 101 Compounding Formulations to Avoid 102 Formulation Development Process 103 Developing a Compounding Formula: Example 1 (USP Compounding Compendium) 104 Developing a Compounding Formula: Example 2 (Stability-Indicating Assay) 106 Compounding Formulation Assessment 108 6 Compounding in House 111 Documentation 111 Master Formulation Record 111 Compounding Record 111 Formulation Record Components 112 Quality Assurance and Quality Control 116 Labeling 118 Packaging and Storage 119 Compounding Techniques 120 Trituration 120 Sifting 121 Geometric Dilution 121 Wetting 121 Colored Tracers 122 Equipment 122 Mortars and Pestles 124 Glassware 125 Containers 125 Scales 127 Spatulas and Measuring Devices 129 Equipment Cleaning 129 Training 130 Formulation Instructions 132 Species-Specific Information 135 Flavoring 135 Toxicities 136 Potency Designations 138 Feasibility for a Veterinary Clinic 139 Index 141

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Book SynopsisApractical guide to interpreting sperm morphology of domestic animals Sperm Morphology of Domestic Animals is a concise, clinically-oriented resource for discovering any impairment to fertility caused by sperm anomalies in domesticated animals. As a bench-side reference, the book examines common sperm defects, their causes, and their prognosis for fertility. An easy-to-use reference, it is organized according to the placement of the deformity in the sperm to increase the speed of consultation, and to help with diagnosing fertility issues. Focusing particularly on the bull, stud horse, boar, ram, buck, and dog, it contains hundreds of high-quality color images accompanied by brief descriptions for additional diagnostic help. Readers will find: An easy-to-use reference work that is suitable for use next to the microscopeOrganization according to location of abnormalityHundreds if high-quality color images for easy comparisonBrief descriptions accompanying each photo, for additional diagnostic help An ideal resource for veterinarians, andrologists, and veterinary students, Sperm Morphology of Domestic Animals fills a gap in current reproductive medicine resources with detailed information that is easy to consult.Table of ContentsPreface ix About the Companion Website x Introduction 1 Section I Head Abnormalities 11 1 Pyriform and Tapered Heads 13 2 Nuclear Vacuolation, Including the Diadem Defect 20 3 Macrocephalic and Microcephalic Sperm 29 4 Rolled Head–Nuclear Crest–Giant Head Syndrome 32 5 Abnormal DNA Condensation 34 6 Acrosome Abnormalities 36 7 Normal Detached Heads and Free Abnormal Heads 44 8 Decapitated Sperm Defect 47 Section II Midpiece Abnormalities 49 9 Proximal Cytoplasmic Droplet 51 10 Pseudodroplet 58 11 Mitochondrial Sheath Defects 59 12 Corkscrew Sperm Defect 65 13 Dag Defect 68 14 Distal Midpiece Reflex 72 15 Bowed Midpieces 78 16 Distal Droplets 79 17 Abaxial Midpieces 82 Section III Tail (Principal Piece) Abnormalities 85 18 Tail Stump Defect 87 19 Coiled Principal Pieces 90 20 Double Forms and Accessory Tails 93 21 Bent Principal Pieces 97 22 Short Tail Defect 99 Section IV Aberrations of Stains and Other Cells in the Ejaculate 101 23 Aberrations Due to Staining 103 24 Aberrations Due to Cold Shock 106 25 Round Cells in the Ejaculate 107 26 Teratoids 110 27 Medussa “Cells” 112 28 Aberrations of Semen Quality 113 References 116 Index 125

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Book SynopsisVeterinary Oral Diagnostic Imaging Complete reference on using diagnostic imaging in veterinary dentistry and interpreting diagnostic images in dogs, cats, exotic pets, zoological animals, and horses Veterinary Oral Diagnostic Imaging offers veterinary clinicians a complete guide to using diagnostic imaging for common dentistry and oral surgery procedures in a veterinary practice. It provides guidance on positioning, techniques, and interpreting diagnostic images in the oral cavity, with more than 600 high-quality dental diagnostic images showing both normal anatomy and pathology for comparison. Focusing on dental radiography in dogs, cats, exotic pets, zoological animals, and horses, the book also includes advanced modalities such as MRI, CT, and cone beam CT. Veterinary Oral Diagnostic Imaging covers: History, physiology, and indications for diagnostic imaging of the oral cavity, with information on the history of diagnostic imaging and radiographic image creationDigital dental radiographic positioning and image labeling, covering the parallel technique, bisecting angle, radiographic positioning errors, and labial mountingInterpretation of anatomy, covering normal radiographic anatomy, dentition and tooth numbers, deciduous and permanent teeth of canine and feline patients, eruption patterns and common and uncommon radiographic pathology observed in these animalsStandard imaging, radiographic anatomy, and interpretation of equine patients, as well as exotic pocket pets and zoological animals Focusing on the fundamentals of dental radiographic imaging, interpretation, and applications to the oral cavity, Veterinary Oral Diagnostic Imaging is an essential resource for any veterinarian providing dental services as part of their practice, along with veterinary students and interns.Table of ContentsList of Contributors xv Preface xvii Acknowledgements xix 1 History, Physiology, Modality Options, and Safety for Diagnostic Imaging of the Oral Cavity 1 Brenda L. Mulherin History of Diagnostic Imaging 1 Discovery of X-rays 1 Developing of Safety Measures 1 Shortening of Exposure Time 1 Glass Plates to Film 2 Progression to Digital 2 Philosophy of Diagnostic Imaging 2 Choosing the Appropriate Modality 2 Ability to Interpret Findings 3 Radiographic Indications 3 Documentation of Disease 3 Value of Full-Mouth Radiography 3 American Animal Hospital Association Guidelines Regarding Dental Radiography 3 Intraoral Dental Radiographic Equipment 3 Generators 3 Wall-Mounted Units 4 Handheld Units 4 Mobile Units/Castor-Mounted Units 4 Film 4 Standard Film 5 Digital Image Acquisition 6 Radiographic Imaging 7 Basic Unit of an X-ray 7 Milliamperes (mA), Kilovoltage Peak (kVp), and Exposure Time 8 Radiographic Densities 9 Radiopaque 9 Radiolucent 10 Digital Image Creation 10 Creation of a Digital Image 10 Digital Imaging and Communications in Medicine Format (DICOM) 10 Pixels 10 Advanced Imaging Modalities 10 Computed Tomography 10 Cone Beam Computed Tomography (CBCT) 12 Magnetic Resonance Imaging 13 Definitions Relating to Imaging Modalities 13 Sagittal Plane 13 Transverse Plane 13 Dorsal Plane 14 Computed Tomography Window Width and Window Level 14 Window Width 15 Window Level 15 Other Common Viewing Windows 16 Bone Window 16 Soft Tissue Window 16 Radiation Safety 16 Radiation Safety Apparel 16 Collimation 16 As Low As Reasonably Achievable (ALARA) 17 Time, Distance, and Shielding 17 Time 17 Distance 17 Shielding 17 Radiation Safety Equipment Inspection 17 Protective Apparel 17 Care of Radiation Safety Equipment 18 Radiation Safety Inspection Protocol 19 References 20 2 Digital Dental Radiographic Positioning and Image Labeling 23 Brenda L. Mulherin and Chad Lothamer Benefits to Proper Positioning 23 Practicing Techniques 23 Use of Position Indicating Device (PID) 23 Positioning Techniques 24 Patient Positioning 24 Sternal Recumbency 25 Dorsal Recumbency 25 Lateral Recumbency 25 Sensor/Phosphor Plate/Film Placement 26 Basic Positioning of Sensor 27 Eliminating Unused Film Space 29 Visualization of the Crown and Space Apical to Root 29 Intraoral Parallel Technique 30 Ideal Radiographic Technique 30 Placement of Sensor for Parallel Technique 31 Size Matters 31 Alternative Positioning 32 Parallel Technique for Cats 32 Intraoral Bisecting Angle Technique 32 Plane of the Tooth, Plane of the Film, and the Angle that Bisects 32 Shadow Game: Elongation, Foreshortening, and the Bisecting Angle 32 Axis of the Sensor, the Tooth, and the PID 33 Positioning of the Patient Matters 35 Anatomical Variations 36 Uses of the Bisecting Angle Technique 36 Occlusal Radiographic Technique 37 Feline Maxillary Premolar and Molar Teeth 37 Extraoral Technique 37 “Almost Parallel” or “Near Parallel” Technique 39 Localization of the Palatal Roots 39 Techniques for Imaging Caudal Teeth in Small Patients 43 Technique Errors 44 Foreshortening and Elongation 44 Cone Cutting 46 Missing the Apex 47 Overexposed or Underexposed 49 Artifacts 50 Repeat Radiographs 51 Conclusion 52 References 53 3 Interpretation of Normal Radiographic Anatomy 55 Brenda L. Mulherin Value of Intraoral Radiographic Imaging 55 Quality of Images 56 Exposure Artifacts 56 Positioning Techniques 56 Parallel Technique 56 Bisecting Angle Technique 56 Positioning Artifacts 56 Elongation 56 Foreshortening 56 Cone Cutting 56 Missing the Apex 57 Mounting of Standard Dental Radiographs 57 Types of Mounting 57 Labial Mounting 57 Lingual Mounting 57 Labial Mounting of Standard Dental Radiographic Film 57 Lingual Mounting of Standard Radiographic Film 57 Digital Radiographic Mounting 58 Labial Mounting-Positioning of Teeth 59 Determining Maxilla from Mandible 59 Determining Right from Left 59 Modified Triadan Numbering System 62 Deciduous versus Permanent Teeth 65 Eruption Patterns 65 Mixed Dentition 66 Interpretation of Images 70 Tooth Root Numbers 75 Maxillary Teeth 75 Mandibular Teeth 77 Evaluation of the Structures 82 Crown 84 Root 90 Bone 105 Interpretation of Radiographic Shadows 105 Nomenclature 107 Where to Begin? 109 Conclusion 110 References 117 4 Interpretation of Common Oral Pathology in the Canine Patient 119 Brenda L. Mulherin and Chanda Miles Periodontal Disease 119 Stages of PD 120 Types of Bone Loss 123 Horizontal Bone Loss 123 Vertical Bone Loss 123 Furcation Bone Loss 124 Supernumerary Roots and Teeth 129 Canine Tooth Resorption 131 Types of Tooth Resorption 132 External Tooth Resorption 132 External Surface Resorption 132 Internal Tooth Resorption 134 Treatment of Tooth Resorption 134 Odontogenic Cysts 135 Dentigerous Cysts 135 Periapical Cysts 137 Treatment for Odontogenic Cysts 138 Tooth Fractures 138 Root Fractures 142 Retained Tooth Roots 142 Endodontic Disease 143 Etiology 143 Radiographic Signs of Endodontic Disease 148 Widened PDL Space 148 Loss of Lamina Dura 148 Periapical Lucency 148 External and Internal Root Resorption 149 Widened Pulp Canal 150 Pulp Canal Calcification 150 Apical Periodontitis 151 Acute Apical Abscess 151 Chronic Apical Abscess 152 Endodontic Therapy 154 Root Canal Therapy 154 Vital Pulp Therapy 156 Attrition and Abrasion 157 Eruption Abnormalities 159 Persistent Deciduous Teeth 159 Unerupted Teeth 162 Abnormal Eruption 163 Conclusion 165 References 165 5 Interpretation of Common Pathology in the Feline Patient 167 Brenda L. Mulherin and Chanda Miles Periodontal Disease 167 Types of Bone Loss 168 Buccal Alveolar Expansile Osteitis (BAEO) 168 Tooth Resorption 168 Stages and Types of Feline Tooth Resorption 177 Stages of Tooth Resorption 177 Types of Tooth Resorption 180 Criteria for Performing Crown Amputation/Intentional Root Retention 180 Supraeruption/Extrusion 185 Osteomyelitis and Osteitis 185 Retained Tooth Roots 187 Endodontic Disease 187 Conclusion 190 References 198 6 Oral Surgery: Neoplasia and Cystic Conditions 199 Megan Mickelson Radiographic Indications of Neoplasia (Benign and Malignant) 199 Benign Oral Tumors 200 Canine Acanthomatous Ameloblastoma (CAA) 200 Peripheral Odontogenic Fibroma (POF) 200 Feline Inductive Odontogenic Tumor (FIOT) 201 Malignant Oral Tumors 201 Nontonsillar Squamous Cell Carcinoma (SCC) 201 Papillary Squamous Cell Carcinoma (PSCC) 203 Oral Malignant Melanoma (MM) 204 Fibrosarcoma (FSA) 206 Osteosarcoma (OSA) 206 Multilobular Osteochondrosarcoma (MLO) 208 Radiographic Indications of Cystic Conditions 209 Dentigerous Cyst 209 Radicular Cyst 212 Canine Furcation Cyst 213 Surgical Ciliated Cyst 213 Lateral Periodontal Cyst 213 Odontogenic Keratocyst (OKC)/Canine Odontogenic Parakeratinized Cyst (COPC) 216 Compound and Complex Odontomas 216 Limitations of Dental Radiography for Neoplasia 216 Conclusion 230 References 230 7 Interpretation of Uncommon Pathology in the Canine and Feline Patient 235 Brenda Mulherin, Chanda Miles, and Michael Congiusta Introduction 235 Uncommon Conditions with Predilection for Canine Patients 235 Craniomandibular Osteopathy (CMO) 235 Idiopathic Calvarial Hyperostosis 237 Periostitis Ossificans (PO) 237 Malformed Roots/Root Hypoplasia 238 Dens Invaginatus/Dens in Dente 240 Uncommon Conditions Observed in both Canine and Feline Patients 245 Masticatory Myositis 245 Pulp Stones and Denticles 246 Osteosclerosis 247 Renal Secondary Hyperparathyroidism 248 Enamel Pearls 253 Uncommon Conditions with Predilection for Feline Patients 253 Dentition Abnormalities 253 Fused Roots 254 Supernumerary Roots 256 Supernumerary Teeth 257 Abnormal Eruption 257 Unerupted Teeth 258 Patellar Fracture and Dental Anomaly Syndrome (PADS) or Knees and Teeth Syndrome 258 Conclusion 262 Acknowledgment 262 References 262 8 Diagnostic Imaging of Exotic Pet Mammals and Zoo Animals 265 June Olds Dental Diagnostic Imaging for Nontraditional (Exotic) Animals 265 General Considerations for Exotic Companion Mammals 266 Restraint 266 Knowledge of Normal Anatomy 266 General Positioning and Projection Recommendations 267 Standard Radiography 267 Standard Radiographic Positions 267 Intraoral Radiographs 272 Intraoral Films Used Extraorally 275 Magnification Techniques 275 Anatomical Variations 275 Rabbits 275 Guinea Pigs and Chinchillas 276 Rats, Mice, Hamsters, Gerbils, and Other Commonly Kept Rodent Pets 283 Ferrets 287 African Pygmy Hedgehogs 287 Sugar Gliders 289 Prairie Dogs (Cyomys ludovicianus) 293 Captive Nondomestic or “Wild” Mammals 293 Nonhuman Primates 293 Carnivores 297 Radiographic Positioning and Techniques in Captive Animals 297 Animal Training 300 Other Dental Conditions in Zoologic Animals 304 Trauma 304 Attrition 304 Macropod Progressive Periodontal Disease (MPPD) 304 Molar Progression 308 Advanced Diagnostic Imaging in Exotic Pet Mammals and Zoo Animals 308 Standard Computed Tomography 308 Cone Beam Computed Tomography 312 Micro-computed Tomography 316 Considerations for Computed Tomography 321 Conclusion 326 Acknowledgment 327 References 327 9 Diagnostic Imaging and Interpretation of the Equine Patient 331 Joan Howard, Molly Rice, Kara Frerichs, and Beatrice Sponseller Introduction to Equine Dental Radiographs 331 Radiation Safety 332 Radiographic Systems 332 Direct Digital Radiographic System (DR) 332 Computed Tomography 332 Standard Radiographic System 332 Radiographic Technique 332 Guidelines for Radiographic Views 332 Concepts to Understand 332 Directing the Primary Beam Through the Interproximal Spaces 333 Open Mouth Oblique Cheek Teeth Projections 334 Radiographic Views 334 Lateral View 334 Dorsoventral View 336 Dorsal Ventral Oblique Projection of the Maxillary Cheek Teeth 338 Ventral Dorsal Oblique Projection of the Maxillary Cheek Teeth 340 Ventral Dorsal Oblique Projection of the Mandibular Cheek Teeth 340 Dorsal Ventral Oblique Projection of the Mandibular Cheek Teeth 340 Occlusal Intraoral View of the Maxillary Incisors and Canines 340 Occlusal Intraoral View of the Mandibular Incisors and Canines 343 Evaluation of an Image 346 Labial Mounting 346 Radiographic Anatomy 347 Radiographic Changes in Dental Disease 350 Equine Odontoclastic Tooth Resorption and Hypercementosis (EOTRH) 352 Apical Infections 353 Periodontal Disease 354 Sinusitis 356 Neoplasia 357 Other Suggested Abnormalities to be Radiographed 358 Conclusion 360 Acknowledgment 372 References 372 10 Advanced Imaging of the Oral Cavity 373 Stephanie Goldschmidt Introduction to the Use of Advanced Imaging Techniques in the Maxillofacial Region 373 Magnetic Resonance Imaging (MRI) 373 Technical Principles of MRI 373 T1- and T2-Weighted Sequences 374 Other MRI Sequences 375 Indications for Use of MRI over CT in the Maxillofacial Region 376 Temporomandibular Joint Disease (TMD) 376 Salivary Gland Disease 376 Abnormalities in the Muscles of Mastication and Inability to Open/Close the Mouth 376 Conclusions on the Clinical Indication for Use of MRI 377 Computed Tomography (CT) 379 Technical Principles of Multidetector CT (MDCT) Scanners 380 Technical Principles of Cone Beam CT (CBCT) Scanners 382 Viewing CT Images 383 Differences in Image Characteristics Between CBCT and MDCT 387 Spatial Resolution 387 Soft Tissue Imaging 387 Artifacts 389 Other Impactful Differences in Practical Use Between MDCT and CBCT 389 Indications for Use of Either MDCT or CBCT in the Maxillofacial Region 389 Maxillofacial Trauma 389 Bony Pathology 390 Osteomyelitis/Osteonecrosis 390 Fibro-Osseous Disease 390 Osseous Neoplasia 391 Clefts 392 Indications for Multidetector CT only (not CBCT) in the Maxillofacial Region 395 Oral Neoplasia with a Soft Tissue Component 395 Soft Tissue Pathology 395 Indications for CBCT only (not MDCT) in the Maxillofacial Region 395 Dentoalveolar Trauma 396 Periodontal Disease 396 Endodontic Disease 396 Tooth Resorption 399 Diagnosis and Treatment of Missing Teeth 401 Conclusions on the Clinical Indication for Use of CBCT Versus MDCT 402 References 402 Index 407

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Book SynopsisTable of ContentsList of Contributors xxi Acknowledgments xxiii About the Companion Website xxiv Part I Core Concepts 1 1 Introduction 3 Pierce, BA, MTS, PhD References 5 Further Reading 5 2 What Is Animal Hospice and Palliative Care? 6 Amir Shanan, DVM and Tamara Shearer, MS, DVM, CCRP, CVPP, CVA, MSTCVM Introduction 6 History of Animal Hospice 8 Scientific and Philosophical Roots 8 Early Beginnings 9 Organization and Recognition 10 Animal Hospice and Human Hospice 12 Ethical and Legal Differences 12 Economic Differences 13 Summary 14 References 14 3 The Interdisciplinary Team 16 Tammy Wynn, MHA, LISW, RVT, CHPT and Amir Shanan, DVM Interdisciplinary Teams in Human Hospice and Palliative Care 16 Interdisciplinary Teams (IDT) in Animal Hospice and Palliative Care 17 Operating a Successful Interdisciplinary Team 18 Common Mission and Vision 18 Team members, Their Roles, and Responsibilities 19 Effective Communication and Collaboration 22 Summary 25 References 25 4 Quality of Life Assessments 26 Jessica Pierce, BA, MTS, PhD and Amir Shanan, DVM What are Quality of Life Assessments and Why are they Important in End- of- Life Care? 26 Definitions of Quality of Life 26 Quality of Life and Well- being 27 Quality of Life Assessments and Euthanasia Decisions 28 The Importance of Context in Quality of Life Assessment 28 Quality of Life and Patient- Centered Care 29 Physical Discomfort, Emotional Distress, Pain, and Suffering 30 Coping and Adaptation 32 Measuring Quality of Life in Animal Patients 33 A Variety of Approaches to QOL 34 McMillan’s Affect Balance Model 35 Weighing Positive and Negative Affect at the End of Life 36 Quality of Life Assessment Tools 36 Quality of Life Assessment Over Time 38 Summary 40 References 40 Further Reading 42 5 Recognizing Distress 44 Emma K. Grigg, PhD, CAAB, Suzanne Hetts, PhD, CAAB, and Amir Shanan, DVM Stress, Distress, Emotions, and Suffering 44 The Stress Response 44 What Is Distress? 45 Behavioral Needs of Dogs and Cats 46 Assessing Quality of Life in Nonhuman Animals 47 Relevance to Animal Hospice and Palliative Care (AHPC) 48 Are Humans Adept at Recognizing Emotional States in Animals? 49 Body Language of Fear, Anxiety, and Pain 49 Fear- and Discomfort- Related Body Postures Commonly Observed in Dogs and Cats 49 Pain- Related Facial Expressions Commonly Observed in Dogs and Cats 51 Relevance to Animal Hospice and Palliative Care (AHPC) 52 Changes in Behavioral Patterns as Indicators of Pain and Distress 53 Do Animals “Hide” their Pain? 53 Decreased Response to and Engagement with their Surroundings 54 Unusual Patterns of Movement or Positioning 55 Focused Attention to One Specific Body Part 56 Displacement Behaviors 56 Can Sick Animals Suffer from Boredom? 56 Relevance to Animal Hospice and Palliative Care (AHPC) 57 End- of- Life Decisions 57 Conclusion 58 References 58 6 Balancing Efficacy of Treatments Against Burdens of Care 62 Kristina August, DVM, GDVWHM, CHPV Establishing the Goals of Care 63 Assessing Efficacy and Burdens of Medical Treatment 66 Assessment of Treatment Efficacy 66 Appetite and Hydration Needs at the End of Life 66 Emotional Well- Being 67 Animal Individual Preferences 67 Do- Not- Resuscitate and “Advance Directives” 67 Assessment of Treatment Burden 68 Assessing Diagnostic Procedures 69 Adverse Events: Treatment- Related Consequences 70 Steroids and End- of- Life Care 71 Adverse Events: Indirect Consequences of Medical Care 71 Assessing the Burdens of Caregiving 72 Conclusion 73 References 73 7 Ethical Decision- Making in Animal Hospice and Palliative Care 76 Jessica Pierce, BA, MTS, PhD and Amir Shanan, DVM A Method for Moral Decision- Making 77 Part 1: Clinical Considerations and Their Moral Dimensions 77 Part 2: Patient Considerations: How the Animal Feels and What the Animal Wants 78 Understanding What Animals Want 79 Will to Live 79 Respecting What Animals Want 80 Suffering 80 Part 3: Human Factors Influencing Moral Decision- Making 83 Providing Adequate Information 85 Guiding Client Decision- Making: How Much Is Too Much? 86 Guiding the Choice between Euthanasia and Continued Palliative Care 88 Societal Ethics and the Role of Cultural Values 90 Ethical Business Practices 91 Moral Stress, Decisional Regret, and Mental Health 91 Conclusion: Finding the Path of Least Regrets 92 References 93 8 Supportive Relationships: Veterinarians and Animal Hospice Providers’ Nonmedical Roles 95 Amir Shanan, DVM and Laurel Lagoni, MS Defining the Nonmedical Roles of Veterinary Professionals and Other Animal Hospice Providers (except licensed mental health professionals) 98 The Role of Source of Support 98 The Role of Educator 100 The Role of Facilitator 100 The Role of Resource and Referral Guide 101 Resources 101 Extended Services 102 Limiting the Role of Animal Hospice Veterinary Professionals and Other Providers (except licensed mental health professionals) 102 Know Thyself, Healer 105 Conclusion 105 Grief Support Resources 106 Memorials and Grief Support Resources 106 Counselors and Grief Support 106 Grief Support Training 106 Books for Caregivers 106 Books for Veterinarians 107 References 107 9 Management and Administration: Business Models 108 Kathleen Cooney, DVM, MS, CHPV, CCFP Guidelines for Animal Hospice and Palliative Care Practice 108 Service Delivery Models 109 Model 9.1 Hospice in the Veterinary Hospital Setting 110 Model 9.2 Hospice with Specialized Mobile Veterinarians 112 Model 9.3 Animal Hospice Case Managers 113 Model 9.4 Animal Hospice Sanctuaries/Rescues 114 Practicalities of Starting an Animal Hospice Service 114 Telehealth as a Bridging Component for all Models 117 Conclusion 118 References 119 Part II Patient Care 121 10 Cancers in Dogs and Cats 123 Alice Villalobos, DVM, FNAP and Betsy Hershey, DVM, DACVIM (Oncology), CVA Approach to End- of- Life Cancer Patients 124 Tumors of the Skin and Soft Tissues 124 Canine Lymphoma 125 Head and Neck Cancer 126 Oropharyngeal and Neck Tumors in Dogs and Cats 126 Nasal Passage Cancer 127 Brain Tumors 127 Cancer of the Skeletal System 128 Abdominal Tumors 129 Hemangiosarcoma in Dogs 129 Transitional Cell Carcinoma 129 Hepatic, Pancreatic, Intestinal, Adrenal, and Renal Cancer 130 Chest Cavity Tumors 130 Palliative Cancer Medicine 131 Advances in Noninvasive Technology for the Diagnosis of Cancer 134 Summary 135 Conflicts of Interest 135 References 135 11 Integrative Therapies for Palliative Care of the Veterinary Cancer Patient 138 Betsy Hershey, DVM, DACVIM (Oncology), CVA Nutrition and Food Therapy 138 Herbs and Supplements 141 Herbal Supplements 141 Antioxidants 143 Medicinal Mushrooms 143 B Vitamins 143 Digestive Enzymes 144 Probiotics 144 Vitamin d 144 Omega- 3 Polyunsaturated Fatty Acids (PUFAS) 145 Curcumin 145 High Dose IV Vitamin C Therapy 145 Acupuncture 146 Manual Massage Therapies 147 Energy Therapy (Biofield Therapy) 148 Sound Therapy 148 Reiki, Therapeutic Touch, and Healing Touch Therapies 148 Ozone Therapy 148 Hyperbaric Oxygen Therapy 150 Cannabis and Cannabidiol (CBD) Oil 151 Essential Oils 154 Homeopathy and Homotoxicology 155 Chiropractic 156 Photobiomodulation Therapy (PBM) 157 Summary 158 References 158 12 Chronic Kidney Disease 163 Shea Cox, DVM, CHPV, CVPP and Christie Cornelius, DVM, CHPV Description of Disease 163 Disease Trajectory 163 Clinical Manifestations of Disease 163 Management 164 Management of Factors that Accelerate Chronic Kidney Disease Progression 164 Dehydration 164 Nonregenerative Anemia 164 Systemic Hypertension 165 Proteinuria and Activation of the Renin–Angiotensin–Aldosterone System 165 Renal Secondary Hyperparathyroidism 165 Symptomatic, Supportive, and Palliative Therapies 166 Oral Ulcerations and Uremic Gastritis 166 Nausea/Vomiting 166 Constipation/Obstipation 167 Loss of Appetite 167 Urinary Tract Infection 167 Hyperphosphatemia 168 Hypokalemia 168 Seizures 168 Dietary Considerations 168 Other Comfort Measures 168 Conclusion 168 References 169 13 Congestive Heart Failure 171 Shea Cox, DVM, CHPV, CVPP and Christie Cornelius, DVM, CHPV Description of Disease 171 Disease Trajectory 171 Clinical Manifestations of Disease 171 Palliative Management 172 Pulmonary Edema/Cardiac Function 172 Diuretics 173 Ace Inhibitors 173 Positive Lonotrope, Vasodilator 174 Calcium Channel Blocker 174 Pleural and Abdominal Effusion 174 Hypokalemia 174 Prerenal Azotemia 174 Balancing Renal and Cardiac Disease 174 Coughing 175 Respiratory Distress 175 Aortic Thromboembolism 175 Dietary Considerations 176 Heart- Gut Interactions in Heart Failure 176 Other Considerations 176 Conclusion 176 References 176 14 Respiratory Distress 178 Cheryl Braswell, DVM, DACVECC, CHPV, CHT-V, CVPP Airway Collapse 178 Description 178 Trajectory/Prognosis 179 Manifestations 179 Management 179 Pharmacologic 179 Physical 179 Nutritional 180 Surgery 180 Brachycephalic Airway Obstruction Syndrome 180 Description 180 Trajectory/Prognosis 180 Manifestations 181 Management 181 Pharmacologic 181 Physical 181 Nutrition 181 Surgery 181 Airway Inflammation 181 Description 181 Trajectory/Prognosis 182 Manifestations 182 Management 182 Pharmacologic 182 Physical 183 Nutritional 183 Pneumonia 183 Description 183 Trajectory/Prognosis 183 Manifestations 183 Management 183 Pharmacologic 183 Physical 184 Nutritional 184 The Suffering of Dyspnea: Palliative Care 184 References 185 15 Gastrointestinal Conditions 186 Shea Cox, DVM, CHPV, CVPP and Christie Cornelius, DVM, CHPV Inflammatory Bowel Disease 186 Description of Disease 186 Disease Trajectory 186 Clinical Manifestations of Disease 186 Palliative Management 186 Medical Support 186 Immunosuppressive Therapy 186 Antibiotic Therapy 187 Additional Support Therapy 187 Nutritional Support 188 Fecal Microbial Transplantation (FMT): The Ultimate Probiotic 188 Pancreatitis 188 Description of Disease 188 Disease Trajectory 188 Clinical Manifestations of Disease 189 Palliative Management 189 Medical Support 189 Analgesia 189 Antiemetics 189 Antibacterials 189 Immunosuppressants 189 Subcutaneous Fluid Therapy 189 Nutritional Support 189 Cholangitis/Cholangiohepatitis Syndrome 190 Description of Disease 190 Disease Trajectory 190 Clinical Manifestations of Disease 190 Palliative Management 190 Medical Support 190 Antimicrobial Therapy 190 Immunosuppressive Therapy 190 Analgesia 191 Antiemetics 191 Support Therapy 191 Subcutaneous Fluid Therapy 191 Nutritional Support 191 Conclusion 191 References 191 16 Musculoskeletal Disorders 193 Tamara Shearer, MS, DVM, CCRP, CVPP, CVA, MSTCVM Osteoarthritis 193 Description 193 Trajectory/Prognosis 194 Manifestations 194 Management 195 Cranial Cruciate Ligament Pathology 197 Description 197 Trajectory/Prognosis 197 Manifestations 197 Management 197 Medical Management 198 Surgical Management 198 Strains, Sprains, and Myofascial Pain 199 Description 199 Trajectory/Prognosis 199 Manifestations 199 Management 199 Coxofemoral Luxation 200 Description 200 Trajectory/Prognosis 200 Manifestations 200 Management 200 Fractures 201 Description 201 Trajectory/Prognosis 201 Manifestations 201 Management 201 Conclusion 201 References 202 17 Nervous System Disease 204 Tamara Shearer, MS, DVM, CCRP, CVPP, CVA, MSTCVM Intervertebral Disc Disease 204 Description 204 Trajectory/Prognosis 205 Manifestations 205 Management 206 Cervical Spondylomyelopathy 207 Description 207 Trajectory/Prognosis 208 Manifestations 208 Management 208 Fibrocartilagenous Embolic Myelopathy 208 Description 208 Trajectory/Prognosis 209 Manifestations 209 Management 209 Vestibular Disorders 209 Description 209 Trajectory/Prognosis 210 Manifestations 210 Management 210 Laryngeal Paralysis/Geriatric Onset Laryngeal Paralysis Polyneuropathy 211 Description 211 Trajectory/Prognosis 211 Manifestations 211 Management 211 Degenerative Myelopathy 212 Description 212 Trajectory/Prognosis 213 Manifestations 213 Management 213 Disorders of Micturition/Urination 214 Description 214 Trajectory/Prognosis 214 Manifestations 214 Management 214 Bladder Is Difficult or Cannot Be Expressed 215 Bladder Can Be Expressed with Effort 215 Straining to Urinate with Spurts of Urine Produced 215 Bladder Easily Expressed with Continuous Leakage 216 Urine Leakage when Urine Accumulates 216 Ancillary Therapies for Micturition Disorders 216 Conclusion 216 References 216 18 Cognitive Dysfunction 219 Tamara Shearer, MS, DVM, CCRP, CVPP, CVA, MSTCVM Description 219 Trajectory/Prognosis 220 Manifestations 220 Management 221 Client Education and Prevention 221 Behavior Modification and Environmental Enhancement 221 Diet Modification 222 Supplements 222 Alternative Care 223 Pharmaceutical Interventions 223 Conclusion 224 References 225 19 Pharmacology Interventions for Symptom Management 227 Shea Cox, DVM, CHPV, CVPP Introduction 227 Pain 227 Clinical Signs of Pain 227 Behavioral Indicators of Pain 227 Pharmacology for Pain Management 228 Nonsteroidal Anti- Inflammatory Drugs 228 Glucocorticoids 229 Acetaminophen 229 Opioids 229 Tricyclic Antidepressants 231 Serotonin- Norepinephrine Reuptake Inhibitors 232 Anticonvulsants 232 N- methyl- d- aspartate Receptor Antagonists 232 Monoclonal antibodies 233 Pharmacologic Protocols 233 Assessing Response to Treatment 234 Anxiety 234 Dysphoria 236 Weakness or Fatigue 237 Respiratory Symptoms 237 Dyspnea 237 Cough 239 Nausea and Vomiting 239 Anorexia and Cachexia 240 Dehydration 241 Constipation 241 Oral Health 242 Ulcers 242 Dry Mouth (Xerostomia) 242 Conclusion 242 References 242 20 Physical Medicine and Rehabilitation for Hospice and Palliative Care Patients 245 Tamara Shearer, MS, DVM, CCRP, CVPP, CVA, MSTCVM Physical Medicine vs. Physical Rehabilitation 245 Considerations for Physical Medicine with Hospice and Palliative Care Patients 245 Assistive Devices: Priority in Hospice Care 247 Slings and Harnesses 247 Straps and Bands 248 Protective Footwear 248 Support of Joints: Orthotic Devices 249 Support for Paralysis/Pararesis: Carts and Drag Bags 250 Four Simple but Important Manual Therapies and Therapeutic Exercises 250 Range of Motion 250 Assisted Standing and Walking 251 Proprioceptive and Balance Techniques 251 Massage and/or Tui-na 252 The Role of Acupuncture for Hospice and Palliative Care Patients 252 Innovative and Noninvasive Techniques 254 Kinesiology Taping 254 Extracorporeal Magnetotransduction Therapy: EMTT 257 Extracorporeal Shockwave Therapy 257 Targeted Pulsed Electromagnetic Field Therapy 258 Other Therapeutic Modalities for Hospice and Palliative Care Patients 259 Thermal Modalities 259 Photobiomodulation Therapy (also known as Laser Therapy) 260 Pulsed Signal Therapy 261 Electrotherapy 261 Therapeutic Ultrasound 262 Manual Therapy/Medical Manipulation/Chiropractic Care 262 Conclusion 263 References 263 21 Integrative Medicine in Animal Hospice and Palliative Care 265 Kristina August, DVM, GDVWHM, CHPV Terms 265 Going Mainstream 266 Safety and Adverse Reactions 267 Healing Philosophies 268 Nutritional Supplements 269 Herbal Medicine 269 Essential Oils 271 Other Therapies 272 Ensuring Quality of Life 273 Reliable Choices and Client Education 273 Conclusion 274 Educational Opportunities 274 References 274 22 Nursing Care for Seriously III Animals: Art and Techniques 278 Shea Cox, DVM, CHPV, CVPP and Mary Ellen Goldberg, CVT, LVT, SRA-retired, CCRVN, CVPP, VTS-lab animal-retired, VTS-Physical Rehabilitation-retired, VTS-anesthesia/analgesia-Honorary Introduction 278 Nurses’ Medical Roles 279 Intake 279 Planning of Care 279 Ongoing Monitoring and Assessments 279 Frequency of Assessments 279 Parameters of Assessments 279 Assessment of Pain 280 Pain Scales 280 Assessment of Other Signs of Discomfort 282 Assessment for Dehydration 282 Assessment of Medication Administration 282 Assessment of Mobility 282 Assessment of Mental and Emotional Status 283 Delivery of Care: Nursing Care Considerations 284 Comfort for the Patient 284 Oral and Ocular Comfort 284 Nutrition 286 Hydration 287 Treating Fluid Deficit (Dehydration) 287 Maintenance Fluids Administration 288 Calculating Fluid Deficit 288 Hygiene 288 Bedding 288 Environment 289 Mobility 289 Range of Motion (ROM) 289 Transitions 290 Standby Assisted Standing 290 Weight Shifting Exercises 290 Assisted Standing Exercises 290 Aids for Assisted Standing 290 Mobility Carts 290 Nursing Care for Recumbent Patients 290 Urination 291 Defecation 291 Respiration 291 Skin Care 292 Mobilizing the Recumbent Patient 292 Nurses as Advocates and Educators 292 Nurses’ Role as Advocates for Patient and for the Caregiver 293 Nurses’ Role as Educators 293 Awareness of Signs of Pain 294 Hygiene and Safety 294 Death and Dying 295 Conclusion 295 References 296 Further Reading 298 23 Comfort Care During Active Dying 299 Gail Pope and Amir Shanan, DVM Natural Death and Euthanasia 299 Goals of Caring for the Dying Patient 301 Advance Preparation and Education of Caregivers and Hospice Team 301 Desirable Environment of Care 302 Prognostication 303 Changes During Early and Late Stages of Active Dying 303 Available Information 303 Changes During Early Stages of Active Dying 303 Physical Changes 303 Behavioral Changes 304 Indications of Pain 304 Changes During Late Stages of Active Dying 305 Behavior, Sleeping Pattern, Responsiveness 305 Respiration 305 Eyes, Mucus Membranes, Jaw, and Extremities 306 Muscle Twitching, Stretching, and the Agonal Position 306 Odor 306 Summary 306 At the Time of Death 306 The Different Types of Active Death 308 Managing Clinical Signs During Active Dying 309 Management of Pain 309 Management of Anxiety and Agitation 310 Fatigue and Weakness 310 Loss of Ability to Swallow 311 Respiration 311 Cardiac Dysfunction and Renal Failure 311 Diminished Skin Vitality 311 Mucosal and Conjunctival Care 312 Incontinence 312 Administration of Medications, Fluids, and Food 312 Administration of Fluids 313 Administration of Food 314 Administration of Medications 314 Summary 315 References 315 24 Euthanasia in Animal End- of- Life Care 318 Kathleen Cooney, DVM, CHPV, DACAW Decision- Making for the Animal Hospice Patient 318 Advance Preparation and Education of the Professional Team 319 Advance Preparation and Education of Caregivers and Family 321 Euthanasia Setting: Desirable Environment of Care 323 Euthanasia Techniques and Criteria 324 Intravenous Injection 325 Intracardiac Injection 325 Intraperitoneal Injection 327 Intrahepatic Injection 328 Intrarenal Injections 329 Variability and Unpredictability 330 References 331 Part III Caregiver Needs: Providing Support 333 25 Caregivers’ Emotional Burden: Understanding, Acknowledging, and Addressing Caregivers’ Emotional Burden 335 Amir Shanan, DVM Caregiving Experience 336 The Mental Health Impact of Caregiving 339 Supporting caregivers’ Emotional Needs 340 The Role of a Licensed Mental Health Professional 343 Qualified Mental Health Professionals 345 Summary 346 References 347 26 Caregiver Burden in the Companion Animal Owner 349 Mary Beth Spitznagel, PhD and Mark D. Carlson, DVM What Is Caregiver Burden? 349 A Word About Research Data, the Terminology Used, and this Article’s Audience 349 Caregiver Burden Is Present in Owners of Seriously Ill Companion Animals 350 How Caregiver Burden Differs from Other Client Experiences in this Context 350 How Does Caregiver Burden Affect the Veterinary Client? 351 Impact of Caregiver Burden on the Client 351 Impact of Caregiver Burden on the Patient 352 Research- Based Suggestions for Interacting with the Burdened Owner 352 Understand the Owner’s Perspective 352 Collaborate on the Care Approach 353 Lighten the Load 353 One Size Does Not Fit All: Toward Individualized Client Interactions 354 Interacting with the Distressed Client 354 Interacting with the Resilient Client 355 Interacting with the Non- Distressed Client 355 Interacting with the “Other Influences” Client 355 More than Compassion Fatigue: When Client Burden Transfers to the Clinician 355 The Burden Transfer DANCE 356 Conclusions 357 References 357 27 Addressing Spiritual Needs of Caregivers 360 Carol Rowehl, LVT, MAR, STM Spiritual Needs of Caregivers 361 Spiritual Distress 362 Taking a Spiritual History 363 When to Call in the Experts (and Who Are the Experts?) 364 Spiritual Questions Unique to Veterinary Practice and Hospice and Palliative Care 366 Including a Chaplain on the Interdisciplinary Veterinary/Hospice Team 367 Resources 370 References 371 28 Factors Contributing to the Decision to Euthanize Pet Dogs and Cats 374 Nathaniel Cook, DVM, CVA, CVFT, CTPEP and Beth Marchitelli, DVM, MS Introduction 374 Pet Factors: Symptoms and Clinical Signs that Affect Quality of Life 374 Appetite and Weight Loss 375 Appetite 375 Weight Loss 377 Elimination Disorders 377 Impaired Mobility 379 Sensory and Cognitive Decline 380 Dyspnea and Respiratory Compromise 381 Perception of Pain 382 Pet Factors: Severe Illness Diagnosis 382 Cancer 382 Organ Failure: Congestive Heart Failure 383 Endocrine Disorders: Diabetes Mellitus 384 Pet Owner Factors: Psychosocial Factors of Caregiving 384 Conclusion 385 References 385 29 Supporting Other Needs 389 Shea Cox, DVM, CHPV, CVPP and Mary Ellen Goldberg, CVT, LVT, SRA-retired, CCRVN, CVPP VTS-lab animal-retired, VTS-Physical Rehabilitation-retired, VTS-anesthesia/analgesia-Honorary Caring for the Caregiver: Addressing Emotional and Physical Needs 389 Maintaining Self- Care 390 Maintain Personal Nutrition and Sleep 390 Engage in Exercise 390 Make Time for Relaxation 390 Time Considerations of Hospice Care 391 Managing Time Commitments of Care 391 Tips for Balancing Caregiving with Ongoing Responsibilities 391 Understanding the Physical Labor of Care 391 Utilizing Proper Body Mechanics During Delivery of Care 392 Environmental Considerations of Hospice Care 393 Assessment of the Physical Space 393 Household and Environmental Modifications 393 Financial Considerations of Hospice Care 393 Cost of Medications 394 Cost of Diagnostics 394 Cost of Other Healthcare Providers 394 Cost of Environmental Modifications 394 Cost of End- of- Life Care 394 Helping to Defer Costs of Hospice Care 395 Pet Health Insurance 395 Equipment Rental, Recycling, and Reduced Cost Programs 395 Creating a Memorial Fund 395 Creating a Donation Bank 395 References 396 Further Reading 396 30 Aftercare 398 Coleen A. Ellis, CT, CPLP Hospice Options and Accompanying Rituals 398 Emotional Support: Honoring the Journey 401 Assisting Children, Other Pets, and Family Members in Their Journey 402 After- Death Care Options 402 Summary 406 References 406 Index 407

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Book SynopsisComprehensive reference describing in-depth anatomy and histology of the domestic chicken, depicted through high quality macro- and micro-photographs Anatomy and Histology of the Domestic Chicken is a state-of-the-art atlas of avian anatomy that provides a complete collection of both original gross anatomy and histology photographs and texts of all body systems of the birds based on the domestic chicken to depict anatomic features. Using cutting-edge technology to create visualizations of anatomic structures, this exhaustive reference includes both gross anatomical structures/organs and their histological details next to each other. This approach enables readers to understand the macro- and micro-pictures of each organ/structure under study. The text includes a total of more than 200 high-resolution, high quality color images and diagrams. Written by two highly qualified professors with significant experience in the field, Anatomy and Histology of the Domestic Chicken includes information on: External features of the body, including regions, features, ornaments, shape, feathers, skin, and the uropygial gland Musculoskeletal characteristics including cartilage and bone formation and classification, as well as flight and ambulatory muscles Digestive system, including the beak, esophagus, crop, proventriculus, ventriculus, intestines, and accessory glands Respiratory system, including external nares, nasal cavity, trachea, upper larynx, syrinx, lungs, and air sacs Urinary system, including kidneys and the ureter, cloaca-urodeum, and genital system, covering differences between males and females Endocrine system, including pituitary, pineal, adrenal, pancreas, thyroid, and parathyroid glands Nervous system with central and peripheral divisions and sense organs including eye and ear Lymphatic system, with descriptions of the primary and secondary lymphatic organs Egg anatomy and development of the chick embryo Applied anatomical concepts important for clinical maneuvers and necropsy With comprehensive coverage of the subject and highly detailed photographs included throughout the text, Anatomy and Histology of the Domestic Chicken is an indispensable resource for breeders, veterinarians, researchers, avian biologists, pathologists, and students in animal sciences and veterinary fields.

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Book SynopsisEducational Principles and Practice in Veterinary Medicine An in-depth, veterinary-centered reference to the discipline of education Educational Principles and Practice in Veterinary Medicine provides a detailed, comprehensive reference to the discipline of education both broadly and as it relates to veterinary medicine. Written for veterinary faculty members, instructors, and educators in other health professions, the book offers an in-depth examination of knowledge and skills related to veterinary education. It discusses educational theory, how people learn, the structure and function of higher education, and educational technologies, among many other topics of importance. Sections cover educational leadership; professional development for faculty; research methods and study design; administration; outcomes and assessment; accreditation; and the roles of the professional program instructor. Educational Principles and Practice in Veterinary Medicine: Provides a detailed exposition to the discipline of education, encompassing both theory and practiceCovers essential topics such as educational theory, the structure and function of higher education, and educational technologies, all tailored to veterinary educationActs as a reference to education-related knowledge and skills, with an emphasis on how these topics relate to veterinary medicineSupports veterinary faculty and instructors interested in taking their knowledge and skills to the next level Educational Principles and Practice in Veterinary Medicine offers veterinary faculty and instructors a complete resource for understanding the field of education and improving their skills and knowledge.

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Book Synopsis

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Book SynopsisPRINCIPLES OF GOAT DISEASE AND PREVENTION Learn to diagnose, treat, and clinically manage a wide variety of diseases in goats?? In Principles of Goat Disease and Prevention, veterinary medicine expert Dr. Tanmoy Rana delivers a singularly informative resource covering infectious diseases affecting ruminant animals. The book offers key insights into the most important aspects of common and unusual diseases affecting goats, providing clinical management best practices for veterinary practitioners engaged in the diagnosis and treatment of ruminant diseases.?? The author explains ruminant disease, as well as its diagnosis and treatment, systematically, explaining the etiopathogenesis of various pathogens, clinical symptoms, disease prevention and control, and the most recent advances in identifying and treating diseases in goats. Readers will also find: A thorough introduction to managing nutrition in goatsComprehensive explorations of the handling and restraining of goats for the purpose Table of ContentsContributors xxiii Preface xxvii Acknowledgments xxix 1 Introduction 1 K. Justin Davis, Sunita Choudhary, and Tanmoy Rana 1.1 Introduction 1 1.2 Global Distribution 1 1.3 Advantages of Goat Rearing 1 1.4 Goat Milk and Products 2 1.5 Chevon 3 1.6 Fiber and Other Products 4 1.7 Goat Production System 4 1.8 Constraints in Goat Farming 4 1.9 Economics of Disease in Goats 4 1.10 Goat Diseases and Public Health 5 1.11 Prevention of Disease 5 Multiple-Choice Questions 6 References 7 2 Nutrition and Management of Goats 9 Rohit Kumar 2.1 Essential Nutrients for Goats 9 2.1.1 Protein 9 2.1.2 Carbohydrates 9 2.1.3 Fats 10 2.7 Conclusion 18 Multiple-Choice Questions 18 References 19 Further Reading 19 3 Handling and Restraining of Goats 21 Falguni Mridha 3.1 Purposes of Handling and Restraining 21 3.2 Basics of Animal Behavior Associated with Handling 21 3.2.1 Experience of Handler 22 Multiple-Choice Questions 28 References 30 4 Clinical Findings of Diseases of Goats 33 Sunita Choudhary, K. Justin Davis, G.K. Chetan Kumar, and Pratishtha Sharma 4.1 Diagnosis of Skin Diseases by Clinical Findings 33 4.1.1 Pruritus 33 4.1.2 Hyperkeratosis 34 4.1.3 Abscesses, Nodules, Scales, and Crust 34 4.1.4 Alopecia 34 4.1.5 Pigmentary Changes 35 Multiple-Choice Questions 45 References 47 5 Collection, Preservation, Processing, and Dispatch of Clinical Material of Goats 49 Gauri A. Chandratre 5.1 Why Are Samples Collected? 49 5.2 Who Should Collect the Samples? 50 5.3 Sample Collection and Emergency Preparedness 50 5.4 Various Samples and Sample Collection Methods from Diseased Goats 50 Multiple-Choice Questions 60 References 61 6 Parasitic Diseases of Goats 63 G.K. Chetan Kumar 6.1 Common Trematode Diseases of Goats 63 6.1.1 Fasciolosis 63 6.1.2 Dicrocoeliosis in Goats 65 6.1.3 Paramphistomiasis in Goats 66 6.2 Common Tapeworm Diseases of Goats 67 Multiple-Choice Questions 76 References 77 7 Mycoplasma, Rickettsia, and Chlamydia Diseases of Goats 79 Ranjani Rajasekaran, Hridya Susan Varughese, Padmanath Krishnan, and Panikkaparambil Shilpa 7.1 Mycoplasma 79 7.1.1 Contagious Caprine Pleuropneumonia 79 7.1.1.1 History 79 Multiple-Choice Questions 91 References 93 Further Readings 93 Mycoplasma 93 Rickettsia 94 Chlamydia 94 8 Bacterial Diseases of Goats 95 Vipin Maurya 8.1 Anthrax 95 8.1.1 Etiology 95 8.1.2 Clinical Features 95 Multiple-Choice Questions 109 References 110 9 Fungal Diseases of Goats 111 Pardeep Sharma and Tanmoy Rana 9.1 Fundamentals of Fungal Diseases of Goats 111 9.2 Dermatophytosis in the Goat: Ringworm, Tinea 111 9.2.1 Etiology 111 9.9 Conclusion 124 Multiple-Choice Questions 124 References 125 10 Viral Diseases of Goats 127 Abha Tikoo, Savleen Kour, and Rajesh Agrawal 10.1 Peste des Petits Ruminants 127 10.2 Goat Pox 128 10.3 Foot and Mouth Disease 130 10.4 Caprine Arthritis and Encephalitis 131 10.5 Rabies 132 Multiple-Choice Questions 133 References 134 11 Transboundary, Emerging, and Exotic Diseases of Goats 137 Subir Singh 11.1 Peste des Petits Ruminants 138 11.1.1 Etiology and Epidemiology 139 11.1.2 Transmission 140 11.1.3 Clinical Findings 140 11.6 Conclusion 152 Multiple-Choice Questions 152 References 153 12 Production Diseases of Goats 155 Gaurav Charaya, Jasleen Kaur, Chinmoy Maji, and Tanmoy Rana 12.1 Body Condition Scoring in Goats and Its Significance in Relation to Production Diseases 155 12.2 Factors Affecting Nutritional Requirements in Goats 155 12.3 Major Production Diseases Encountered in Goats 156 Multiple-Choice Questions 163 References 164 Further Reading 164 13 Poisoning in Goats 165 Kamlesh A. Sadariya, Shailesh K. Bhavsar, and Tamanna H. Solanki 13.1 Toxic Plant Poisoning 166 13.1.1 Lantana camara Poisoning 167 13.1.2 Cyanogenic Glycoside/Cyanide Poisoning 168 13.1.3 Subabul Poisoning 168 13.11 Conclusion 176 Multiple-Choice Questions 177 References 178 14 Genetic Diseases of Goats 183 Simant Kumar Nanda 14.1 Congenital Abnormalities 184 14.1.1 Congenital Abnormalities of Joints and the Skeleton 184 14.1.2 Akabane Virus (Bunyavirus) 184 14.1.3 Hereditary Chondrodysplasia (Spider Lamb Syndrome) 185 14.18 Conclusion 193 Multiple-Choice Questions 193 References 194 15 Protozoan Diseases in Goats 195 Vikrant Sudan, Deepak Sumbria, and Rabjot Kour 15.1 Babesiosis 195 15.1.1 Life Cycle 195 15.1.2 Pathogenesis 196 15.1.3 Symptoms 196 Multiple-Choice Questions 204 References 205 16 Metabolic Diseases in Goats 207 Antônio C.L. Câmara and Benito Soto-Blanco 16.1 Polioencephalomalacia 207 16.1.1 Etiology 207 16.1.2 Clinical Signs 208 16.1.3 Ancillary Diagnostic Tests 208 Multiple-Choice Questions 218 References 219 17 Nutritional Deficiency Diseases in Goats 221 Chinmoy Maji, Suman Biswas, and Jasleen Kaur 17.1 Deficiency of Water 221 17.2 Deficiency of Energy 222 17.3 Deficiency of Protein 223 Multiple-Choice Questions 233 References 234 18 Diagnostic Techniques in Goats 237 Mohammad I. Yatoo, Oveas R. Parray, Rather I. Ul Haq, and Mohsina Mushtaq 18.1 Diagnosis of Infectious Diseases 237 18.1.1 Case History 237 18.1.2 Clinical Signs 237 18.1.3 Physical Examination 237 Multiple-Choice Questions 248 References 249 19 Management of Pain from Surgery and Lameness in Goats 251 Joe S. Smith and Pierre-Yves Mulon 19.1 Pathophysiology of Pain 251 19.2 Arthritis 251 19.3 Recognition of Pain 252 19.4 Analgesics Available 252 19.4.1 Non-steroidal Anti-inflammatory Drugs 252 19.4.1.1 Flunixin Meglumine 255 19.4.1.2 Meloxicam 255 19.4.1.3 Other Non-steroidal Anti-inflammatory Drugs 255 19.4.2 Opioids 255 19.4.2.1 Morphine 256 19.4.2.2 Butorphanol 256 19.4.2.3 Fentanyl 256 19.4.2.4 Other Opioids 256 19.4.3 α 2 Adrenergic Agonists 256 19.4.4 Ketamine 257 19.4.5 Gabapentin 258 19.5 Non-pharmacological Therapies 258 19.6 Regulatory Concerns 258 19.7 Strategies for Analgesia in Goats 258 19.7.1 Preoperative Analgesia 258 19.7.2 Epidural 258 19.7.3 Regional Local Anesthesia 260 19.7.4 Topical Agents 261 19.8 Management of Osteoarthritis 261 19.9 Future Directions 261 19.10 Conclusion 262 Multiple-Choice Questions 262 References 264 20 Antimicrobial Resistance in Goat Production Practices 267 Bhupamani Das, Kruti Debnath Mandal, Abhinav Suthar and Chinmoy Maji 20.1 Causes of Antimicrobial Resistance 267 20.1.1 Indiscriminate Use of Drugs 267 20.1.2 Unchecked Antimicrobial Dosage 268 20.1.3 Inadequate Diagnostics 268 20.1.4 Veterinary Practitioners 268 20.1.5 Poor Hygiene and Sanitation Practices 268 20.1.6 Lack of Effective Preventive and Control Strategies 269 20.1.7 Poor Surveillance and Monitoring 269 20.2 Types of Antimicrobial Resistance 269 20.2.1 Natural Resistance 269 20.2.2 Acquired Resistance 269 20.2.3 Side Resistance 270 20.2.4 Cross-Resistance 270 20.2.5 Multiple Resistance or Multiple Drug Resistance 270 20.3 Mechanism of Antimicrobial Resistance 270 20.3.1 Natural Resistance 270 20.3.1.1 Permeability Barrier 270 20.3.1.2 Biofilm Formation 271 20.3.2 Acquired Resistance 271 20.3.2.1 Vertical Gene Transfer 271 20.3.2.2 Horizontal Gene Transfer 271 20.4 Barriers to Effective Surveillance of Antimicrobial Resistance 273 20.5 Present Status of Antimicrobial Resistance in Goat Production Practices 279 20.6 Conclusion 279 Multiple-Choice Questions 279 References 280 21 Prevention and Control Strategy in Combating Diseases of Goats 285 Amita Tiwari, Shivangi Udainiya, and Tanmoy Rana 21.1 Control of Infectious Diseases 285 21.1.1 Biosecurity Measures 285 21.1.2 Vaccination 288 21.2 Control of Endoparasites/Internal Parasites 290 21.2.1 Nematodes 290 21.2.2 Cestodes 290 21.2.3 Trematodes 290 21.2.4 Lungworms 291 21.2.5 Deworming Schedule for Goats 291 21.2.6 Common Measures for Control of Endoparasites 291 21.3 Control of Ectoparasites/External Parasites 292 21.3.1 Ticks 292 21.3.1.1 Treatment, Prevention, and Control of Ticks 293 21.3.2 Lice 293 21.3.2.1 Treatment and Control of Lice Infestation 293 21.3.3 Mites 293 21.3.3.1 Psoroptic Mange 293 21.3.3.2 Sarcoptic Mange 294 21.3.3.3 Demodectic Mange 294 21.3.3.4 Control and Treatment Strategy for Mange Mites 294 21.4 Control of Protozoal Infections 294 21.4.1 Coccidiosis 294 21.4.1.1 Treatment and Control of Coccidiosis 294 21.4.2 Cryptosporidiosis 295 21.4.3 Toxoplasmosis 296 21.5 Diseases of Nutrition and Metabolism 296 21.5.1 Mineral Deficiencies 296 21.5.2 Vitamin Deficiencies 296 21.5.3 Milk Fever 296 21.5.4 Grass Tetany 297 21.5.5 Ruminal Acidosis 297 21.6 Poisonous Plants 297 21.7 Pregnancy Toxemia 297 Multiple-Choice Questions 298 References 298 Answers 299 Index 321

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Book Synopsis* Published as part of the prestigious Wiley-Blackwell UFAW Animal Welfare series. * A complete and balanced overview of the issues surrounding the use of animals in scientific research, with a focus on animal welfare implications and ethics of animals in research.Trade Review“To me, overall this is a very good book that provides a balanced view of the issues around animal welfare. It is a good read.” (Laboratory Animal Practitioner, 1 May 2015) “This book is geared toward members of institutional animal care and use committees, researchers, and veterinarians and is a practical guide for discussions pertaining to the welfare of animals used in research.” (JAVMA, 15 December 2014) “To me, overall this is a very good book that provides a balanced view of the issues around animal welfare. It is a good read.” (Laboratory Animal Practitioner, 1 October 2014) “Overall, the factual description of how animals are used in research balanced by the author’s personal experiences and perspective makes this book highly readable. ‘The Welfare of Animals used in Research’ is a great addition, which will be essential reading for those working with laboratory animals and of general interest to those new to the field.” (Veterinary Record, 12 July 2014)"Overall, this book is a welcome arrival to a debate that is too often split between misrepresentative arguments recycled from activist websites on one side and defensive responses dumbing down the complexity of scientific discovery on the other. I recommend it to anyone who believes the debate over animal research is of sufficient importance to be worth being well-informed." (Australian Veterinary Journal, 7 July 2016)Table of ContentsForeword vii Preface ix Dedication and Acknowledgements xi 1 Introduction 1 1.1 Reasons for Using Animals in Research 1 1.2 Where Animal Research is Carried Out 3 1.3 Numbers of Animals Used 4 1.4 Harmful and Harmless Research 6 1.5 How Much Suffering is Caused by Research? 7 1.6 Attitudes to Animal Experimentation 9 1.7 The Moral Imperative 18 1.8 Trust in the System 22 2 The Use of Legislative and Other Controls on Animal Research to Meet Public Expectations and Improve Animal Welfare 26 2.1 Introduction 26 2.2 Levels of Control 29 2.3 Scope of Controls 37 2.4 Systems for Ethical Review and Authorisation 42 2.5 Performance and Engineering Standards 45 2.6 Roles and Responsibility 50 2.7 Legislation and Licences 51 2.8 Enforcement and Failure to Comply 52 3 Animal Rights and Animal Welfare: Philosophy and Science 58 3.1 Introduction 58 3.2 Animal Rights and Animal Welfare: Making a Distinction 59 3.3 Animal Welfare Science 63 3.4 Funding and Promoting Animal Welfare Research 85 3.5 The Benefits of Animal Welfare Science 86 4 Species Choice and Animal Welfare 88 4.1 Introduction 88 4.2 Consciousness/Sentience: Evidence for Protecting Particular Taxa 89 4.3 Are Some Species Capable of Suffering More Than Others? Neurological Complexity and Capacity to Suffer 104 4.4 Beastly Bias in Practice 108 4.5 An Evolutionary Approach to Assessing Suffering 120 5 The Harm–Benefit Judgement 123 5.1 Introduction 123 5.2 Who Should Be Involved? 126 5.3 Factors To Be Considered in Harm–Benefit Decisions 129 5.4 Decision Tools 154 5.5 The Requirement for Ethical Review 157 6 Improving the Welfare of Animals Used in Research: The 3Rs 159 6.1 Introduction: The Origins of the 3Rs 159 6.2 Replacement 163 6.3 Reduction 169 6.4 Refinement 175 6.5 Conflicts Between the 3Rs 201 6.6 Training 202 6.7 Sources of Information on the 3Rs 203 7 Science and Animal Welfare: A Partnership 205 7.1 Replacement Methods: Scientific and Other Advantages 205 7.2 Reduction: Scientific and Other Advantages 209 7.3 Refinement: Scientific and Other Advantages 210 7.4 Changes in Laboratory Animal Science and Challenges for the Future? 219 7.5 Maintaining the Momentum 223 7.6 Conclusion 224 References 226 Glossary 259 Index 262

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Book SynopsisThe application of evidence-based veterinary medicine (EBVM) can assist in improving and optimising the diagnosis, prognosis, control, treatment and ultimately the welfare of animals. It can also provide the user with a methodology for appropriate, patient orientated life-long, self-directed, learning. To practise evidence-based veterinary medicine we require a range of skills that we may not have. This book explains what evidence-based veterinary medicine is and shows how it can be applied to veterinary practice to improve the quality of care for patients and provide informed choices for owners. It provides the reader with a toolkit of skills necessary to practise evidence-based veterinary medicine. This book is aimed at practitioners but will be of interest to veterinary surgeons at any stage of their training or career wishing to learn about EBVM.Trade Review"It addresses an emerging topic, which has 'been around' in human medicine for several years. The topic has yet to be taken up widely in veterinary medicine." "I would suspect that most US veterinary school libraries would purchase a copy as well as the obvious UK market." Mike Thrusfield, Royal (Dick) School of Veterinary Medicine, Edinburgh. "An overview of this topic is timely, especially as it is forming part of the undergraduate curriculum." John Innes, Orthopaedic Specialist, University of Bristol. "An interesting and understandable presentation introducing the relatively novel concept of EBVM." Lab Animal News (US)Table of ContentsPreface. Acknowledgements. 1. Introduction. 2. Turning Information Needs into Questions. 3. Sources of Information. 4. Searching for Evidence. 5. Research Studies. 6. Appraising the Evidence. 7. Diagnosis. 8. Clinical Diagnostic Decision Support (CDDSSs). 9. Decision Analysis, Models and Economics as Evidence. 10. EBVM: Education and Future Needs. Glossary. Bibliography. Answers to Review Questions. Index

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Book SynopsisSuitable for both laboratory personnel and zoo workers, this book discusses the care of primates in captivity.Trade Review"This book covers all aspects of primate care and management, in the laboratory and environment and zoos. It covers the welfare and ethics of primate captivitiy, housing, husbandry, environmental enrichment, nutritional requirements, breeding issues, primate diseases, transportation and quarantine procedures. This book would be of use to veterinarians and those who work with or who are involved in the care of captive primates." (CAB Abstracts, 2005) "This book is a good source of reference for people working with primates or starting off a collection. There has been a lack of up-to-date concise books on this topic and the Handbook of Primate Husbandry and Welfare fills this niche." (Primate Eye, Official Journal of Primate Society of Great Britain, 2005) "The book is a useful compendium of information on health, nutrition, housing, and management of the most commonly used primates in biomedical and behavioural research... it should be on the shelf of every animal facility that houses nonhuman primates" (International Journal of Primatology, April 2006) "Thorough guide to the…care of laboratory and zoo-held monkeys…useful introduction into the mainly diverse and interconnected issues surrounding care and management of primates in captivity." (Journal of Wildlife Diseases)Table of ContentsPreface vii Acknowledgements viii 1 Primates: Their characteristics and relationship with man 1 What is a primate? 1 Primate characteristics 3 Why are primates special? 6 Ethical considerations of animals in captivity 8 Legal considerations 11 Further reading 12 2 The physical environment 15 Considerations in accommodation design 15 Indoor/outdoor/combination facilities? 22 Environmental conditions 24 Waste management 29 Further research needed 29 Further reading 30 3 Staff management and health and safety 33 Selection of staff 33 Training of staff 33 Health and safety issues 33 Lone working 41 Employee security 41 Further reading 41 4 Nutrition 43 Natural feeding ecology 43 Diet formulation and processing 45 Energy requirements 45 Carbohydrate, protein and fat 46 Minerals and vitamins 48 Water 49 Supplements 50 Different life stages 51 Hand rearing of infants 55 Further reading 57 5 Physical well-being 59 Assessment of physical health 59 Quarantine programme 67 Health-screening programme 68 Common infectious diseases 73 Husbandry-related diseases 89 Sedation of primates 92 Further reading 92 6 Psychological well-being 99 Strategy for psychological well-being 99 Environmental enrichment 100 Assessment of psychological health 111 Further reading 112 7 Training of primates 115 Why train primates? 115 Sociality and psychological well-being in primates 116 Primate behaviour 120 Modification of behaviour 121 Further reading 128 8 Breeding 129 Group systems and sizes 129 Primate fertility 132 Natural suppression of fertility 134 Reproductive cycles 137 Artificial control of reproduction 138 Pregnancy diagnosis 139 Parturition 139 Lactation and weaning 141 Breeding lifespan 143 Selection of breeding males 144 Further reading 145 9 Sourcing and transporting primates 149 Background 149 Transportation 152 Provision during transport 157 Post-move monitoring 158 Further reading 160 Index 163

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Book SynopsisThere has been a recent explosion of active concern in matters of animal welfare. The science behind animal welfare has progressed significantly, new codes of practice and legislation have come into to being, and innovative methods to assess welfare schemes for food production have emerged. Part of a major animal welfare series, Animal Welfare: Limping Towards Eden is John Webster''s new and groundbreaking work on animal welfare. Building on his first book, the highly acclaimed Animal Welfare: A Cool Eye Towards Eden, it not only critically reviews areas of development, but looks to how animal welfare can be improved in the future. Special consideration is given to: Defining animal welfare (''fit and happy'') and establishing a systematic approach for its evaluation (the ''five freedoms''); Providing a sound ethical framework that affords proper respect to animals within the broader context of our duties as citizens to the welTrade Review"Professor Webster remains at all times the epitome of credibility" "The book quickly offers remedies in the form of practical and realistic hope, conveyed with an honest, personal and at times amusing style." Veterinary Record, 2005 Table of ContentsPreface. Acknowledgements. 1. Introduction: Facts and Values. 2. Challenge and Response. 3. Sentience, Sense and Sufferering. 4. Husbandry and Welfare on the Farm: Assessment and Assurance. 5. Animals for Food: Indutrialized Farming, Pigs and Poultry. 6. Animals for Food: Cattle and Other Ruminants. 7. Animals for Food: Handling, Transport and Slaughter. 8. Animals for Science and Biotechnology. 9. Animals for Sport. 10. Animals as Pets. 11. Limping Towards Eden: Stepping Stones. Further Reading. Index.

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Book SynopsisThe Sciences of Animal Welfare analyses the diverse, interconnecting subjects which constitute this fascinating multidisciplinary field, whilst also considering the limitations and benefits of those subjects to the development and future of Animal Welfare Science.Trade Review"The book is appropriately organized and clearly written, and there are abundant reference citations. Each chapter starts with a detailed outline to quickly guide readers to the paragraph of interest. " (Vet Med Today, 15 June 2010) "Provides a clearly reasoned and thorough theoretical framework for the evaluation and solution of animal welfare problems in the highly technological environment in which many veterinarians work. Veterinarians, managers, and technicians involved with intensive animal care and use programs in any setting will find this book extremely valuable... The book requires readers to pay close attention, but it will reward them with a valuable new perspective and approach to solving critical problems." (JAVMA, June 2010) "Provides a solid foundation for understanding and developing perspective on issues of animal welfare which have previously been addressed by varied facets of society in a more abstract manner. The authors present their well-informed opinions but advocate strongly as well for the application of objective measurement techniques and evidence-based approaches to inform the evolution of the field. The use of summary phrases to introduce each new thought or section is an outstanding approach to presenting the information, which other books would do well to adopt." (Doody's, February 2010)Table of ContentsForeword. Preface. Acknowledgements. Part 1 Introduction. 1 Focus of Animal Welfare. Part 2 Paths from the Past. 2 Agricultural Sciences and Animal Welfare: Crop Production and Animal Production. 3 Veterinary Science and Animal Welfare. 4 Genetics, Biotechnology and Animal Breeding: Mixed Blessings. Part 3 Assessment of Animal Welfare. 5 Animal Welfare, Grading Compromise and Mitigating Suffering. 6 Standardized Behavioural Testing in Non-Verbal Humans and Other Animals. Part 4 Human Inputs and Animal Welfare. 7 Human–Animal Interactions and Animal Welfare. 8 Environmental Enrichment: Studying the Nature of Nurture. 9 Social Contexts of Animal Welfare. Part 5 Thinking Outside the Box. 10 Integrated Perspectives: Sleep, Developmental Stage and Animal Welfare. 11 The Wider Context of Animal Welfare Science. References. Index.

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Book SynopsisThe first accessible reference on carrying out veterinary clinical research, covering all the core research methods as well as aspects specific to veterinary medicine. Written for veterinary clinicians, students and researchers who need to learn about research methodology. Special attention is given to ethical and legal issues.Trade Review“Any college-level collection strong in veterinary science needs a handbook [on] how to carry out clinical research … [this book] fits that bill … .Outstanding survey.” California Bookwatch “The first accessible information on how to carry out veterinary clinical research. Covering all the core research methods as well as aspects specific to veterinary medicine. Special attention is given to ethical and legal issues … .This is useful as an introduction to clinical research and as a quick reference for sample size determination.” Doody's ReviewsTable of ContentsForeword. 1. Introduction. 1.1 What Is Veterinary Clinical Research?. 1.2 What Is The ‘Scientific Method’?. 1.3 Errors And Truth. 1.4 Why Do We Perform Veterinary Clinical Research?. 1.5 Research From Practice. References. 2. Establishing The Hypothesis. 2.1 What Is The Question?. 2.2 What Are The Characteristics Of A Good Research Question?. 2.3 Selecting The Research Questions. 2.4 The Hypothesis. 2.5 The Question Doesn’t Translate Into A Hypothesis. 2.6 Initial Study Design. 2.7 Problems With The Research Question And Study Design. Further Reading. Mcqs. Answers To Mcqs. 3. Sampling, Subject Selection Criteria And Recruitment. 3.1 Introduction. 3.2 Surveys. 3.3 Observational Clinical Studies And Clinical Trials. 3.4 The Calculation Of Sample Size. 3.5 Summary. Reference. Further Reading. Mcqs. Answers To Mcqs. 4. Variables. 4.1 Introduction. 4.2 Types Of Variable. 4.3 Measurement Scales. 4.4 Precision And Accuracy. 4.5 Summary. Further Reading. Mcqs. Answers To Mcqs. 5. Introducing Statistics: Preparing To Make A Sample Size Estimation. 5.1 Introduction. 5.2 Statistical Principles. 5.3 Testing For Statistical Significance. 5.4 Other Statistical Tests And Choosing The Appropriate Statistical Test. Reference. Further Reading. Mcqs. Answers To Mcqs. 6. How Many Animals/Patients Are Needed? Estimating The Sample Size. 6.1 Introduction. 6.2 Producing The Sample Size Estimate. 6.3 Sample Size Required Per Group For The Comparison Of Two Means. 6.4 Sample Size Required Per Group For The Comparison Of Multiple Means. 6.5 Sample Size Required Per Group For The Comparison Of Two Proportions. 6.6 Sample Size Techniques For Analytic Studies And Experiments. 6.7 Further Considerations When Estimating Sample Size. References. Further Reading. Mcqs. Answers To Mcqs. Appendix 6.1: Tables Estimating Sample Size Group For Comparing Two Proportions. Appendix 6.2 Tables For Estimating The Sample Sizes When Comparing The Means From Two Groups. Appendix 6.3 Tables For Estimating The Sample Size To Obtain The Value Of A Proportion. Appendix 6.4 Table For Estimating A Sample Size To Obtain A Value For A Continuous Variable With A Particular Confidence Width. Appendix 6.5 Tables For Estimating Sample Sizes For Studies Determining If Correlation Coefficients Differ From Zero. 7. Observational Studies: Cohort Studies. 7.1 Introduction. 7.2 Cohort Studies. 7.3 Prospective Cohort Studies. 7.4 Retrospective Cohort Studies. 7.5 Combined Prospective And Retrospective Survival Cohort Studies Across Time Andplace. 7.6 Nested Case-Control And Case Cohort Studies. 7.7 Multiple-Cohort Studies. 7.8 Planning A Cohort Study. 7.9 Cohort Studies And Prognosis. 7.10 Summary. References. Further Reading. Mcqs. Answers To Mcqs. 8. Cross-Sectional And Case-Control Studies. 8.1 Introduction. 8.2 Cross-Sectional Studies (Prevalence Studies). 8.3 Case-Control (Retrospective) Studies. 8.4 Clinical Questions, Evidence And Experimental Design. 8.5 Summary. References. Further Reading. Mcqs. Answers To Mcqs. 9. Clinical Randomized Controlled Trials. 9.1 Introduction. 9.2 Randomized Controlled Trials. 9.3 Cross-Over Designs. 9.4 Factorial Design Trials. 9.5 Features Of Randomized Clinical Trials. 9.6 Poorly Controlled Or Uncontrolled Trials. 9.7 Protocols. 9.8 Summary. References. Further Reading. Mcqs. Answers To Mcqs. 10. Studies On Diagnostic Tests. 10.1 Introduction. 10.2 Measuring The Specificity, Sensitivity And Prevalence. 10.3 Tests With Continuous Measures. 10.4 Studies That Compare Two Tests To Find Out Which Is Better. 10.5 Prognostic Tests. 10.6 Studies Of Test Reproducibility (Precision). 10.7 Studies On The Impact Of A Test On Patient Outcomes. 10.8 Studies On The Feasibility, Costs And Additional Risks Of Tests. 10.9 Summary Of Clinical Test Study Designs. 10.10 Sources Of Bias In The Evaluation Of Diagnostic Tests. 10.11 Checklist For Studies Of Diagnostic Tests. 10.12 Examples. 10.13 Summary. References. Further Reading. Mcqs. Answers To Mcqs. 11. Designing Questionnaires. 11.1 Introduction. 11.2 Designing A Good Questionnaire. 11.3 Designing Good Questions. 11.4 Design And Structure Of The Questionnaire Forms. 11.5 Reply-Paid Envelope. 11.6 The Covering Letter. 11.7 Pilot Testing. 11.8 Maximizing Response. 11.9 Follow-Up Letters. 11.10 Administration Of The Questionnaire. 11.11 Validation. 11.12 How Things Can Go Wrong. References. Further Reading. Mcqs. Answers To Mcqs. 12. Study Implementation. 12.1 Pilot Studies And Pretesting. 12.2 Quality Control. 12.3 Revising The Protocol Once The Study Has Begun. Further Reading. Mcqs. Answers To Mcqs. 13. Data Management. 13.1 General Considerations. 13.2 Computing Requirements. 13.3 Planning The Management Of Data. 13.4 Definition Or Coding Of Variables. Further Reading. Mcqs. Answers To Mcqs. 14. Writing A Research Protocol And Applying For Funding. 14.1 Writing A Proposal. 14.2 The Elements Of A Proposal. 14.3 What Are The Characteristics Of A Good Proposal?. 14.4 What Happens Once The Proposal Has Been Sent?. 14.5 Sources Of Funding. Further Reading. 15. Writing And Reviewing Scientific Papers. 15.1 Introduction. 15.2 Writing Scientific Papers. 15.3 The Structure Of A Scientific Paper. 15.4 Selecting A Journal. 15.5 Instructions To Authors. 15.6 The Peer Review Process. 15.7 Copyright And Proofs. References. Further Reading. Mcqs. Answers To Mcqs. 16. Ethical And Legal Considerations. 16.1 Ethical Considerations. 16.2 Ethical Principles. 16.3 Ethical Review. 16.4 Informed Consent. 16.5 Criteria For Informed Decision Making. 16.6 Practical Guidelines On Obtaining Consent And Avoiding Problems. 16.7 Other Ethical Issues. 16.8 Data Protection Legislation And Confidentiality. 16.9 The Animals (Scientific Procedures) Act 1986. 16.10 Veterinary Medicines Directorate Animal Test Certificates. References. Further Reading. Mcqs. Answers To Mcqs. 17. Systematic Reviews, Meta-Analysis, Critically Appraised Topics, Decision Analysis, Case Series And Case Reports. 17.1 Systematic Reviews And Meta-Analysis. 17.2 Critically Appraised Topics. 17.3 Decision Analysis. 17.4 Case Series And Case Reports. References. Further Reading. Mcqs. Answers To Mcqs. Index

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Book SynopsisThe second edition of Anaesthetic and Sedative Techniques for Aquatic Animals provided the fisheries and aquaculture industry with vital information on the use of sedation and anaesthetics in the avoidance of stress and physical damage, which can easily be caused by crowding, capture, handling, transportation and release. Now fully revised and expanded, the third edition has maintained its accessible format and incorporates much new emphasis on: Fish pain and welfare: a rapidly developing area of interest and debate Anaesthesia and legislation: with an international perspective Personnel involved in the aquaculture industry including fish farmers, fish veterinarians, fisheries scientists and fish biologists along with small animal veterinarians, animal laboratory managers and government and regulatory personnel will find this book a valuable and practical resource.Trade Review"The authors have written a useful, compact handbook on the anaesthesia and sedation of aquatic animals." Aquaculture InternationalTable of Contents1. Introduction. 2. Defining stress in aquatic animals. 3. Pain in aquatic animals. . 4. The nature of anaesthesia, sedation and analgesia. . 5. The features of anaesthetic agents and their legal use. . 6. Anaesthesia and Legislation. . 7. Factors affecting the response of aquatic ectotherms to anaesthesia. . 8. Anaesthesia of fish. I. Inhalation anaesthesia. . 9. Anaesthesia of fish. II. Inhalation anaesthesia using gases. . 10. Anaesthesia of fish. III. Parenteral and oral anaesthesia. . 11. Anaesthesia of fish. IV. Non chemical methods. . 12. Anaesthesia of Aquatic Invertebrates. . 13. Anaesthesia of Amphibians and Reptiles. 14. Transportation and anaesthesia. 15. Concluding remarks

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Book SynopsisWhilst financial success can provide a short term basis for our motivation and well-being, long term satisfaction is only likely to be achieved if there is harmony between our personal values and goals and our professional objectives, and we are content with the place that our profession occupies within our lives. Bradley Viner What does success in veterinary practice mean to you and how do you hope to achieve it? Going much further than a practice management book, Success in Veterinary Practice will help you to find your answers to the big questions: How will you achieve your goals in your veterinary career? How do you uphold your professional values in a commercial world? How can you improve your work-life balance? Bradley Viner guides you on the development and application of skills and traits needed to improve the quality of care that your practice offers to your clients and patients, the working Trade Review"This book does a good job of gearing the information towards veterinarians and it is useful in helping veterinarians discover what is important to them and how to get the most out of their professional careers and personal lives." (Doody's, 18 November 2011) "SUCCESS IN VETERINARY PRACTICE: MAXIMIZING CLINICAL OUTCOMES AND PERSONAL WELL-BEING provides would-be vets and libraries catering to them a fine survey of what is meant by success in veterinary practice. From setting and achieving goals in a veterinary career to improving work/life balance and changing management techniques for better outcome, this is a dual survey of professional ethics and well-being and is a 'must' for students and new veterinary office practitioners alike." (California Bookwatch, January 2011)"The book encourages veterinary practitioners to adopt a holistic approach to achieving life-long success in veterinary practice, rather than simply focusing on the traditional balance sheet, which only takes into account profit and loss, dollars and cents. It is refreshing to read a text that links the two ideals of successful practice and personal wellbeing, rather than simply linking success to a positive balance sheet." (Australian Veterinary Journal, November 2010) "Due to its ability to engage the reader and encourage free thought, rather than spoon feeding pure data, a wide array of experience levels are ably catered for, which means a veteran practice partner can gain just as much from reading this volume as a relative novice." (Veterinary Record, August 2010) "The book is thought-provoking with many useful insights that can help practitioners." (Veterinary Practice, June 2010) Table of ContentsAcknowledgements. Introduction. Chapter 1 Caring about Quality. Chapter 2 Personal Well-Being. Chapter 3 Beliefs, Values, Goals and Motivation. Chapter 4 Improving Clinical Performance. Chapter 5 Good Communications. Chapter 6 Effective Leadership. Chapter 7 Postgraduate Learning. Chapter 8 The Reflective Practitioner. Chapter 9 The Secrets of Success. References. Index.

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Book SynopsisLadybirds are probably the best known predators of aphids and coccids in the world, though this greatly underestimates the diversity of their biology. Maximising their impact on their prey is an important element in modern conservation biological control of indigenous natural enemies in contrast to the classical approach of releasing alien species.Trade Review“The style in which this book is written encourages a response, and invites readers to draw their own conclusions. The inclusion of the final chapter (Chapter 12, Recent progress and possible future trends in the study of Coccinellidae) is particularly welcome. Coccinellid research is a dynamic field and the authors are emphatic in their hope that the information presented in this text will provide inspiration for further research into the specific biology and ecology of these beetles. For me, reading this book has stimulated a great deal of thought.” (Austral Ecology, 1 October 2013) “This is a very well illustrated and authoritative account, with an excellent set of authors and a very full range of topics . . . Overall this is a rich mine of information and full of important and fascinating detail and it has much to be admired.” (British Ecological Society Bulletin, 1 August 2013) “In summary, this is a comprehensive, well-written, very thoroughly referenced and clearly laid out book . . . The authors and three editors are congratulated for producing what will no doubt be the seminal work on the Coccinellidae for years to come.” (Journal of Insect Conservation, 15 August 2012) Table of ContentsDetailed contents, ix Contributors, xvii Preface, xviii Introduction, xix Taxonomic glossary, xx 1. PHYLOGENY AND CLASSIFICATION, 1 Oldrich Nedve¡d and Ivo Kovár¡ 2. GENETIC STUDIES, 13 John J. Sloggett and Alois Hone¡k 3. LIFE HISTORY AND DEVELOPMENT, 54 Oldrich Nedve¡d and Alois Hone¡k 4. DISTRIBUTION AND HABITATS, 110 Alois Hone¡k 5. FOOD RELATIONSHIPS, 141 Ivo Hodek and Edward W. Evans 6. DIAPAUSE/DORMANCY, 275 Ivo Hodek 7. INTRAGUILD INTERACTIONS, 343 Éric Lucas 8. NATURAL ENEMIES OF LADYBIRD BEETLES, 375 Piotr Ceryngier, Helen E. Roy and Remy L. Poland 9. COCCINELLIDS AND SEMIOCHEMICALS, 444 Jan Pettersson 10. QUANTIFYING THE IMPACT OF COCCINELLIDS ON THEIR PREY, 465 J. P. Michaud and James D. Harwood 11. COCCINELLIDS IN BIOLOGICAL CONTROL, 488 J. P. Michaud 12. RECENT PROGRESS AND POSSIBLE FUTURE TRENDS IN THE STUDY OF COCCINELLIDAE, 520 Helmut F. van Emden and Ivo Hodek Appendix: List of Genera in Tribes and Subfamilies, 526 Oldrich Nedve¡d and Ivo Kovár¡ Subject index, 532 Colour plate pages fall between pp. 250 and pp. 251

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Book SynopsisNutritional Management of Hospitalized Small Animals offers veterinarians, veterinary students and technicians a comprehensive reference to the latest information relating to the principles and practice of nutritional support in small animals that require hospitalization.Trade Review“In short, this book is a succinct, clearly written reference guide that describes patient selection, pathophysiology, and criteria for initiating nutritional support and determining the most appropriate dietary characteristics for each patient .” (Journal of the American Veterinary Medical Association, 15 December 2015) “Critique: Comprised of twenty-three specialized articles ranging from Kathryn E. Michel's 'Nutritional Assessment in Small Animals'; to Iveta Becvarova's 'Tube Feeding in Small Animals: Diet Selection and Preparation'; to Lisa P. Weeth's 'Appetite Stimulants in Dogs and Cats'; to 'Nutritional Support in Exotic Pet Species' by Jeleen A. Briscoe, La Toya Latney, and Cailin R. Heinze, "Nutritional Management of Hospitalized Small Animals" will prove to be an invaluable contribution to professional, animal clinic, and academic library Veterinarian Medicine reference collections and supplemental studies reading lists.” (Midwest Book Review, 1 October 2015) “An essential read for those who are serious about their in-patients!.” (Vet Nurses Today, 1 October 2015)"No veterinary hospital or technician overseeing nutrition should be without this invaluable guide, which packs the latest information and research into discussions of best practices." (Donovan's Literary Services 2016)Table of ContentsContributors vii Preface ix Acknowledgements xi 1 Nutritional assessment in small animals 1 Kathryn E. Michel 2 Estimating energy requirements of small animal patients 7 Daniel L. Chan 3 Routes of nutritional support in small animals 14 Sally Perea 4 Nasoesophageal feeding tubes in dogs and cats 21 Isuru Gajanayake 5 Esophagostomy feeding tubes in dogs and cats 29 Laura Eirmann 6 Gastrostomy feeding tubes in dogs and cats 41 Isuru Gajanayake and Daniel L. Chan 7 Jejunostomy feeding tubes in dogs and cats 54 F. A. (Tony) Mann and Robert C. Backus 8 Minimally invasive placement of postpyloric feeding tubes 65 Matthew W. Beal 9 Tube feeding in small animals: diet selection and preparation 80 Iveta Becvarova 10 Intravenous access for parenteral nutrition in small animals 92 Sophie Adamantos 11 Parenteral nutrition in small animals 100 Daniel L. Chan and Lisa M. Freeman 12 Pathophysiology and clinical approach to malnutrition in dogs and cats 117 Jason W. Gagne and Joseph J. Wakshlag 13 Appetite stimulants in dogs and cats 128 Lisa P. Weeth 14 Adverse food reactions in small animals 136 Cecilia Villaverde and Marta Hervera 15 Nutritional management of short bowel syndrome in dogs and cats 152 Daniel L. Chan 16 Refeeding syndrome in small animals 159 Daniel L. Chan 17 Feeding small animal patients with gastrointestinal motility disorders 165 Karin Allenspach and Daniel L. Chan 18 Immune modulating nutrients in small animals 172 Daniel L. Chan 19 Nutritional management of superficial necrolytic dermatitis in dogs 183 Andrea V. Volk and Ross Bond 20 Nutritional support in acute kidney injury in dogs and cats 193 Denise A. Elliott 21 Nutritional support in hepatic failure in dogs and cats 199 Renee M. Streeter and Joseph J. Wakshlag 22 Nutritional management of the septic patient 210 Daniel L. Chan 23 Nutritional support during acute pancreatitis 219 Kristine B. Jensen and Daniel L. Chan 24 Nutritional support in the mechanically ventilated small animal patient 228 Daniel L. Chan 25 Nutritional support in exotic pet species 234 Jeleen A. Briscoe, La’Toya Latney and Cailin R. Heinze Index 247

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Book SynopsisThe son of a Black mother and white father overcomes family trauma to find the courage of compassion in veterinary practice Rising to accept a prestigious award, Jody Lulich wondered what to say. Explain how he’d been attracted to veterinary medicine? Describe how caring for helpless, voiceless animals in his own shame and pain provided a lifeline, a chance to heal himself as well? Lulich tells his story in In the Company of Grace, a memoir about finding courage in compassion and strength in healing—and power in finally confronting the darkness of his youth.Lulich’s white father and Black mother met at a civil rights rally, but love was no defense against their personal demons. His mother’s suicide, in his presence when he was nine years old, and his sometimes brutal father’s subsequent withdrawal set Lulich on a course from the South Side of Chicago to the Tuskegee School of Veterinary Medicine in Alabama to an endowed chair at the University of Minnesota, forever searching for the approval and affection that success could not deliver. Though shadowed by troubling secrets, his memoir also features scenes of surprising light and promise—of the neighbors who take him in, a brother’s unlikely effort to save Christmas, his mother’s memories of the family’s charmed early days, bright moments (and many curious details) of veterinary practice. Most consequentially, at Tuskegee Lulich rents a room in the home of a seventy-five-year-old Black woman named Grace, whose wholehearted adoption of him—and her own stories of the Jim Crow era—finally gives him a sense of belonging and possibility.Completing his book amid the furor over George Floyd’s murder, Lulich reflects on all the ways that race has shaped his life. In the Company of Grace is a moving testament to the power of compassion in the face of seemingly overwhelming circumstances.Trade Review "In the Company of Grace is haunting and powerful. Jody Lulich has written an absorbing meditation on his lifelong journey from a helpless child who witnesses his beloved mother take her own life, to finding acceptance through the unconditional love of an elderly woman and redemption in caring for animals. An unforgettable and inspiring memoir."—Carolyn Holbrook, author of Tell Me Your Names and I Will Testify "Despite suffering true tragedies as a child, Jody Lulich grew up to be a veterinarian who shows deep compassion to both people and animals. His devotion to his mentor and mother figure, Grace Hooks, inspires admiration and an understanding of a true loving relationship. Don't miss this remarkable book."—Laura Shaine Cunningham, author of Sleeping Arrangements "Lulich's memoir is raw, introspective, and honest."—Insight News

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Book SynopsisVeterinary medicine has undergone sweeping changes in the last few decades. Women now account for 55 percent of the active veterinarians in the field, and nearly 80 percent of veterinary students are women. However, average salaries have dropped as this shift has occurred, and even with women in the vast majority, only 25 percent of leadership roles are held by women.These trends point to gender-based inequality that veterinary medicine, a profession that tilts so heavily toward women, is struggling to address. How will the profession respond? What will this mean for our students and schools? What will it mean for our pets entrusted to veterinarian care? Who has succeeded in these situations? Who is taking action to lead change? What can we learn from them to lead the pack in our lives?Leaders of the Pack, by Julie Kumble and Dr. Donald Smith, explores key themes in leadership and highlights women in veterinary medicine whose stories embody those themes. In it, Kumble and Smith cull over three years of interviews to profile a wide variety of women as they share triumphs and challenges, lucky as well as tough breaks, and the sound advice and words that inspired them to take their careers in unanticipated directions. By sharing unique stories that illuminate different paths to leadership and reflecting on best practices through commentary and research, Leaders of the Pack will allow more female leaders to create wider pathways to the top of their profession.

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Book SynopsisThe very mention of Afghanistan conjures images of war, international power politics, the opium trade, and widespread corruption. Yet the untold story of Afghanistan's seemingly endless misfortune is the disruptive impact that prolonged conflict has had on ordinary rural Afghans, their culture, and the timeless relationship they share with their land and animals. In rural Afghanistan, when animals die, livelihoods are lost, families and communities suffer, and people may perish. That Sheep May Safely Graze details a determined effort, in the midst of war, to bring essential veterinary services to an agrarian society that depends day in and day out on the well-being and productivity of its animals, but which, because of decades of war and the disintegration of civil society, had no reliable access to even the most basic animal health care. The book describes how, in the face of many obstacles, a dedicated group of Afghan and expatriate veterinarians working for a small non governmental organization (NGO) in Kabul was able to create a national network of over 400 veterinary field units staffed by over 600 veterinary para professionals. These paravets were selected by their own communities and then trained and outfitted by the NGO so that nearly every district in the country that needed basic veterinary services now has reliable access to such services.Most notably, over a decade after its inception and with Afghanistan still in free fall, this private sector, district-based animal health program remains vitally active. The community-based veterinary para professionals continue to provide quality services to farmers and herders, protecting their animals from the ravages of disease and improving their livelihoods, despite the political upheavals and instability that continue to plague the country. The elements contributing to this sustainability and their application to programs for improved veterinary service delivery in developing countries beyond Afghanistan are described in the narrative.Table of Contents Foreword Introduction Abbreviations 1. Go See the Warlord 2. Unexpected Destination 3. Negotiating with the Taliban 4. USAID Comes Back to Afghanistan 5. Going to Kabul 6. Introductions 7. Dinner Conversations 8. Starting Up the RAMP 9. Reality Check 10. Veterinarians in Name Only 11. Street Life 12. Unexpected Adventures at the Ministry of Planning 13. Hiring Dr. Nasseri 14. Veterinary Scavenger Hunt 15. Off to the Zoo 16. Ramping Up 17. Aerial View 18. Samaruddin 19. Growing Pains 20. Cold Chain 21. Progress Report 22. At Home in Kabul 23. The Graduates 24. Life at the Office 25. A Raft of Problems 26. The French Connection 27. On Target 28. A Paravet in Parliament 29. Torah! Torah! Torah! 30. Sliding Down the RAMP 31. Goodbye RAMP, Hello ASAP 32. Hints of Trouble to Come 33. The Ambassador 34. Sorrow in September 35. First Annual Convention 36. Front Row Seat 37. Return to Kabul 38. Dr. Noor Jahan 39. Jinns 40. Bombproofing 41. No Dairy Farmers Here 42. Who Are You Again? 43. Too Close for Comfort 44. Afghanization 45. Ahmad Nasir's Cow 46. ASAP Claptrap 47. A Civil Military Affair 48. Hostile Takeover Attempt 49. Good Dollars, Bad Dollars 50. Letting Go 51. Encounter in Tiangi Pass 52. Yankees Cap 53. Teamwork 54. What Were They Thinking? 55. Return 56. Dreams Deferred 57. Coming Full Circle Epilogue: Lessons Learned and Applied Acknowledgments Bibliography Notes Index

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Book SynopsisPioneer Science and the Great Plagues covers the century when infectious plagues - anthrax, tuberculosis, tetanus, plague, smallpox, and polio - were conquered, and details the important role that veterinary scientists played. The narrative is driven by astonishing events that centered on animal disease: the influenza pandemic of 1872, discovery of the causes of anthrax and tuberculosis in the 1880s, conquest of Texas cattle fever and then yellow fever, German anthrax attacks on the United States during World War I, the tuberculin war of 1931, Japanese biological warfare in the 1940s, and today's bioterror dangers. Veterinary science in the rural Midwest arose from agriculture, but in urban Philadelphia it came from medicine; similar differences occurred in Canada between Toronto and Montreal. As land-grant colleges were established after the American Civil War, individual states followed divergent pathways in supporting veterinary science. Some employed a trade school curriculum that taught agriculturalists to empirically treat animal diseases and others emphasized a curriculum tied to science. This pattern continued for a century, but today some institutions have moved back to the trade school philosophy. Avoiding lessons of the 1910 Flexner Report on medical education reform, university-associated veterinary schools are being approved that do not have control of their own veterinary hospitals, diagnostic laboratories, and research institutes - components that are critical for training students in science. Underlying this change were twin idiosyncrasies of culture - disbelief in science and distrust of government - that spawned scientology, creationism, anti-vaccination movements, and other anti-science scams. As new infectious plagues continue to arise, Pioneer Science and the Great Plagues details the strategies we learned defeating plagues from 1860 to 1960 - and the essential role veterinary science played. To defeat the plagues of today it is essential we avoid the digital cocoon of disbelief in science and cultural stasis now threatening progress.Table of Contents Preface Acknowledgments Part I. Prologue 1. The Veterinary Schools of Europe 2. Edward Jenner: Zoologist, Physician, Pioneer 3. William Dick: From Farrier to Veterinarian in Edinburgh 4. The Science Giants of 1860: Pasteur, Virchow, and Darwin 5. Robert Koch: Game Change Part II. Farrier to Veterinarian 6. Emigrants West: Ohio Country, Iowa Territory, and Tejas 7. The Canadian Midwest: Divergence of Lower and Upper Canada 8. Pioneers in the Midwest Frontier: Physicians in Veterinary Practice 9. New Plagues, Civil War, and the United States Department of Agriculture 10. Agriculture and Veterinary Science in the Midwest Part III. Pioneering Veterinary Education 11. Urban East Versus Rural West: Montreal and New York Diss Toronto and Iowa 12. The Pioneer State Colleges: Iowa, Ohio, Pennsylvania, and Cornell 13. Plagues and the Bureau of Animal Industry 14. Bacteriology in the Heartland 15. The 1890s: Horse Markets and Enrollments Drop Part iv. Livestock and Veterinarians Go West 16. Private Veterinary Schools: Chicago, Kansas City, and Indianapolis 17. Public Veterinary Schools: The Second-Generation Pioneers 18. The Bureau of Animal Industry and Hog Cholera 19. Veterinary Education, Charles Stange, and the Flexner Report 20. World War I: Biowarfare, Prejudice, and the U.S. ArmyVeterinary Corps Part v. Ascendance 21. Agricultural Depression Amidst a National Boom: The 1920s 22. 1929: Prelude to Bad Times 23. Public Health and Distrust of Government: The Tuberculin War 24. A Depression Paradox: Culture and Science 25. New Deal: Discoveries in Infectious Disease Part vi. Duty Required 26. War: The Home Front 27. Veterinary Corps and Bioterror 28. Postwar Investigations of Enemy Biological Warfare 29. Prelude to the Science Revolution 30. The Atomic Age Part vii. Transformation 31. New Programs, New Laboratories: Malaria, Polio, and New Viruses 32. Comparative Medicine: Models for Leukemia 33. Grassroots Mandates: The National Research Centers for Livestock Diseases 34. Old Plagues in the Wild: The National Wildlife Centers 35. New Plagues: Scrapie, Mad Cow Disease, and the Prion Part VIII. Epilogue 36. The Farm Crises of 1980–1995: Distrust of Science 37. The Gender Shift 38. Biopolitics 39. Bioterror, Anthrax, and the National Animal Health Networks 40. Anti-Science Scams and Keys to Progress Appendixes Notes Index

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Book SynopsisMicro-organisms and their activities are vitally important to virtually all processes on Earth. Micro-organisms matter because they affect every aspect of our lives – they are in us, on us and around us. Microbiology is the study of all living organisms that are too small to be visible with the naked eye. This includes bacteria, archaea, viruses, fungi, prions, protozoa and algae, collectively known as `microbes’. These microbes play key roles in nutrient cycling, biodegradation/biodeterioration, climate change, food spoilage, the cause and control of disease, and biotechnology. Microbes influence all living things and contribute to all manner of chemical and physical processes. Because these activities are so diverse, the science of microbiology is multidisciplinary, calling on the skills and knowledge of individuals specializing in many different fields of life science, environmental science, and engineering. Microbiology arose, and continues to profit from, several previously independent scientific and medical disciplines, including bacteriology, virology, public health science, clinical microbiology, immunology, parasitology, vaccinology, and a host of other areas of inquiry. The field of Veterinary Microbiology comprises the study of four big areas, bacteria, virus, fungi and parasites. Veterinary Microbiology is concerned with microbial (bacterial, fungal, viral) diseases of domesticated vertebrate animals (livestock, companion animals, fur-bearing animals, game, poultry, fish) that supply food, other useful products or companionship. This book will only concentrate on bacteria. An Introduction about reservoirs, and bacterial pathogenesis is given in Section 1. Intracellular bacteria (Chlamydia and Mycoplasma) that can cause different diseases depending on species and host are discussed in Sections 2 and 3. The next Section (Section 4) is dedicated to Staphylococcus aureus that cause Respiratory disease. Listeria monocytogenes, a Foodborne bacteria, is discussed in Section 5. Sections 6 to 11 are about different agents of disease (Tularemia, Tuberculosis, Botulism, Abortion and Q fever, respectively). The next 3 Sections (Sections 12 to 14) concentrate on tick-borne bacteria (Borrelia, Rickttesia, Anaplasma and Ehrlichia). Section 15 discusses Corynebacterium an emerging bacteria. Most of this bacteria are zoonotic, they can infect both humans and animals, Section 16 focuses on the study of zoonoses.

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Book SynopsisThis ethnography explores the Ngoma healing tradition as practised in eastern Mpumalanga, South Africa. ‘Bungoma’ is an active philosophical system and healing practice consisting of multiple strands that is basedon the notion that humans are intrinsically exposed to each other; while this is the cause of illness, it is also the condition for the possibility of healing. This healing seeks to protect the ‘exposed being’ from harm through augmenting the self. Unlike Western medicine, it does not seek to cure physical ailments but aims to prevent suffering by allowing patients to transform their personal narratives of self. Like Western medicine, it is empirical and is presented as ‘local knowledge’ that amounts to a practical anthropology of human conflict and the environment. The book examines this anthropology through political, economic, interpretive and environmental lenses and seeks to bring its therapeutic applications into relation with global academic anthropology.Trade Review"Healing the Exposed Being is a scholarly, rich and engaging account of the complex and individualised knowledge systems and passages of influence that shape sangoma practices in South Africa. Thornton's descriptions of and insight into the philosophies, rituals, and objects of the sangoma, and the ancestors, spirits and others beings with whom they work, change our view of these healers as custodians of the living, advisers, philosophers and guardians. The book is essential reading for anyone interested in health and illness in the region." - Lenore Manderson, Distinguished Professor of Public Health and Medical Anthropology, University of the Witwatersrand.

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Book SynopsisThere are many ongoing debates within and about the subject of animal welfare. This book distils some of the major themes of current debate into one volume, edited by internationally known names in the field of animal welfare. Each chapter is written by one or more leading experts who discuss, in an even-handed way, a provocative topic that will be of interest to anyone concerned with animal welfare. Issues covered include tail docking, farm animal production, neutering of feral cats and the need to conserve habitats of native wild animals in the face of threats from non-native species. Chapters address the different values and priorities involved in dealing with these issues, including scientific and more explicit ethical approaches. Each chapter ends with questions for discussion that may help readers to engage with these dilemmas.Trade Review"The strength of this book is the comprehensive use of scientific literature to encourage the reader to develop a global perspective on animal sentience and question our treatment of animals. Each chapter is followed by a summary of the chapter and'Questions for Discussion'. These discussion questions would be ideal for students of animal welfare and ethics." - Australian Veterinary Journal Volume 92, No 12, December 2014Table of ContentsI: Preface 1: Introduction: values, dilemmas and solutions II: Dilemmas within animal welfare 2: Tales about tails: is the mutilation of animals justifiable in their best interests or ours? 3: Fat companions: understanding the welfare effects of obesity in cats and dogs 4: Welfare and quantity of life III: Animal welfare and social priorities 5: Improving farm animal welfare: is evolution or revolution needed in production systems? 6: Whom should we eat? Why veal can be better for welfare than chicken 7: Public health and animal welfare IV: Animal welfare and conservation 8: Balancing the need for conservation and the welfare of individual animals 9: Value conflicts in feral cat management: trap-neuter-return or trap-euthanize? V: Conceptual dilemmas 10: Alone or together: a risk assessment approach to group housing 11: What is suffering in animals?

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Book SynopsisVeterinarians often come into contact with the law in cases of animal cruelty, domestic animal and wildlife crimes, and human crimes with an animal element. This book provides practical information and training on how to operate within a crime scene. It covers the tests that may need to be carried out, collecting evidence, preparing reports and giving evidence in court as an expert witness. Concentrating on the basic principles and background knowledge needed, the book includes hair, blood and bite mark analysis as well as an overview of firearms injury. It explores wider concepts such as the human-animal bond and one health, going on to give practical guidance and numerous case studies, which bring the book to life and into the real world of the busy crime scene. Practical Veterinary Forensics is an indispensable guide to all veterinarians working in cases of animal cruelty, abuse and crimes against animals. It is essential for welfare organizations, animal shelters and those requiring an introduction to veterinary forensic science.Table of Contents1: Introduction: What is Veterinary Forensics? 2: Forensic Philosophy 3: Law & Animals 4: Forensic Science and Applications to One Health 5: Evidence Collection and Gathering: The Living Evidence 6: Forensic Examination of Animal Hair 7: Firearms and Ballistics 8: Blood and Blood Pattern Analysis 9: Understanding the Nature of Document Evidence 10: Forensic Toxicology 11: Bitemark Analysis 12: Report Writing 13: The Human-Animal Interaction

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Book SynopsisTrade is an inevitable part of human activity and evolution, but when it involves animals there are important ethical issues that have to be considered. Animal trade is often for economic reasons only, and may be hard to justify ethically. There are significant welfare and environmental costs to animals and human society that must be carefully evaluated before such a trade is sanctioned. Controversial and thought-provoking, this text focuses on the trade in live and dead animals and animal parts. It examines the facts and figures to quantify the scope of the animal trade, concentrating mainly on farm animals, but also covering captive wildlife and companion animals. The book describes welfare, environmental, economic and cultural issues around this trade, debating important ethical considerations for everyone that uses or is otherwise involved with animals, especially people in animal welfare.Table of Contents1: The history of animal trade 2: Trade policies for animal products 3: Trade wars, sanctions and discrimination 4: Trade in meat 5: Trade in some key animal products: dairy, wool and fur 6: Trade in live farm animals 7: Disease transmission and biodiversity loss through the trade in farm animals 8: Trade in horses, cats and dogs 9: Trade in wildlife and exotic species 10: The future of animal trade

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Book SynopsisBehaviour problems are a significant cause of companion animal relinquishment and euthanasia. This book provides up to date information about animal behaviour as well as practical advice on how veterinary practice professionals can manage undesirable animal behaviour and give down to earth, appropriate and trusted advice to owners. This book: Covers the important aspects of behaviour in dogs, cats, rabbits and rodents, parrots and birds, as well as how this behaviour has adapted to the domestic environment. Discusses the role of the veterinary practice in improving the emotional experience of animals attending the veterinary practice, including practice design, socialisation classes for young animals and effective communication with owners. Covers the clinical decision-making process in managing the signs of undesirable behaviour, appropriately handling pets in the practice to minimise distress, as well as: behavioural first aid, referral to a specialist, medical influences on behaviour and decisions about euthanasia.This practical and accessible book gives all the essential information needed by veterinary professionals in order to advise clients on the behaviour and well-being of animals in their care.

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Evidence-based, yet entirely practical, this important new text builds upon the basics of neuroscience to describe the links between olfaction and animal behaviour, and the effects of odours in animal welfare. Animals use smells in a multitude of ways: to orientate themselves, to create social bonds, to recognise food, to initiate reproduction, and to avoid predators and imminent threats such as fire. Starting from the scientific basis of olfaction and odour perception, the book covers pheromones and behavioural tests, before describing the role of olfaction in feeding behaviour, reproduction, disease detection, and animal housing. The book: · is written in an evidence-based way, yet with an easy-to-understand style, making it accessible to non-experts · focuses on animals managed by humans, i.e. farm, zoo, lab and companion species · is illustrated by in-depth research examples of many different species This is a captivating introduction to the world of smells, suitable for advanced students, researchers, and teachers of applied ethology, animal welfare and veterinary science.

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Book SynopsisContemporary and challenging, this thought-provoking book outlines a number of the key dilemmas in animal welfare for today's, and tomorrow's, world. The issues discussed range from the welfare of hunted animals, to debates around intensive farming versus sustainability, and the effects of climate and environmental change. The book explores the effects of fences on wild animals and human impacts on carrion animals; the impacts of tourism on animal welfare; philosophical questions about speciesism; and the quality and quantity of animal lives. The welfare impacts of human-animal interactions are explored, including human impacts on marine mammals, fish, wildlife, and companion and farm animals. Animal Welfare in a Changing World provides: Concise, opinion-based views on important issues in animal welfare by world experts and key opinion leaders. Pieces based on experience, which balance evidence-based approaches and the welfare impacts of direct engagement through training, campaigning and education. A wide-ranging collection of examples and descriptions of animal welfare topics which outline dilemmas in the real world, that are sometimes challenging, and not always comfortable reading. This is a 'must-read' book for animal and veterinary scientists, ethologists, policy and opinion leaders, NGOs, conservation biologists and anyone who feels passionately about the welfare of animalsTable of Contents1: Habitat Loss: Changing How Animals Think? 2: Whale Entanglement – a 21st-century Challenge in the Ocean 3: The Welfare Effects of PCBs in the Ocean 4: The Fence – the Welfare Implications of the Loss of the True Wild 5: Trophy Hunting and Animal Welfare 6: Carry on Carrion: the Fall of the Scavenger 7: Restoring What We Have Destroyed: Animal Welfare Aspects of Wildlife Conservation, Reintroduction and Rewilding Programmes 8: Intensification – the Pressures of Volume 9: Welfare Challenges: Feedlot Cattle 10: Public Opinion and the Retailer: Driving Forces in Animal Welfare? 11: Vertebrate/Invertebrate – When Do We Start Caring? 12: Animal Welfare at Slaughter – a Level Global Playing Field? 13: Precision Livestock Farming: the Future of Livestock Welfare Monitoring and Management? 14: The Paradoxical World of the Dog 15: Animal Experience of Domestication 16: Better to Have Lived and Lost – the Concept of a Life Worth Living 17: If Fishes Feel Pain, What Should We Do? 18: Anthropomorphism: Faulty Thinking or Useful Tool? 19: Speciesism 20: Longevity and Brevity – Is Death a Welfare Issue? 21: Promises and Challenges of Big Data Associated With Automated Dairy Cow Welfare Assessment 22: Animal Welfare: Information in a Changing World 23: Licensed to Harm 24: Animal Watching in Tourism 25: The Rise of the Inclusive Approach to Change in Animal Welfare 26: Animal Welfare Protection in the Face of Shrinking Public Resource

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Book SynopsisContemporary and challenging, this thought-provoking book outlines a number of the key dilemmas in animal welfare for today's, and tomorrow's, world. The issues discussed range from the welfare of hunted animals, to debates around intensive farming versus sustainability, and the effects of climate and environmental change. The book explores the effects of fences on wild animals and human impacts on carrion animals; the impacts of tourism on animal welfare; philosophical questions about speciesism; and the quality and quantity of animal lives. The welfare impacts of human-animal interactions are explored, including human impacts on marine mammals, fish, wildlife, and companion and farm animals. Animal Welfare in a Changing World provides: Concise, opinion-based views on important issues in animal welfare by world experts and key opinion leaders. Pieces based on experience, which balance evidence-based approaches and the welfare impacts of direct engagement through training, campaigning and education. A wide-ranging collection of examples and descriptions of animal welfare topics which outline dilemmas in the real world, that are sometimes challenging, and not always comfortable reading. This is a 'must-read' book for animal and veterinary scientists, ethologists, policy and opinion leaders, NGOs, conservation biologists and anyone who feels passionately about the welfare of animalsTable of Contents1: Habitat Loss: Changing How Animals Think? 2: Whale Entanglement – a 21st-century Challenge in the Ocean 3: The Welfare Effects of PCBs in the Ocean 4: The Fence – the Welfare Implications of the Loss of the True Wild 5: Trophy Hunting and Animal Welfare 6: Carry on Carrion: the Fall of the Scavenger 7: Restoring What We Have Destroyed: Animal Welfare Aspects of Wildlife Conservation, Reintroduction and Rewilding Programmes 8: Intensification – the Pressures of Volume 9: Welfare Challenges: Feedlot Cattle 10: Public Opinion and the Retailer: Driving Forces in Animal Welfare? 11: Vertebrate/Invertebrate – When Do We Start Caring? 12: Animal Welfare at Slaughter – a Level Global Playing Field? 13: Precision Livestock Farming: the Future of Livestock Welfare Monitoring and Management? 14: The Paradoxical World of the Dog 15: Animal Experience of Domestication 16: Better to Have Lived and Lost – the Concept of a Life Worth Living 17: If Fishes Feel Pain, What Should We Do? 18: Anthropomorphism: Faulty Thinking or Useful Tool? 19: Speciesism 20: Longevity and Brevity – Is Death a Welfare Issue? 21: Promises and Challenges of Big Data Associated With Automated Dairy Cow Welfare Assessment 22: Animal Welfare: Information in a Changing World 23: Licensed to Harm 24: Animal Watching in Tourism 25: The Rise of the Inclusive Approach to Change in Animal Welfare 26: Animal Welfare Protection in the Face of Shrinking Public Resource

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Book SynopsisIf a pet has a flea problem, you're probably trying to solve it. Unfortunately, flea infestations are very difficult to eliminate! Thankfully, we now know more about the biology and treatment of fleas than ever before, which has led to safe, effective, and affordable treatments, both on pets and in the home environment. This book provides an easy introduction to fleas for pet owners and the veterinary professionals advising them, to help effectively prevent, control and treat infestations. Detailing the most effective treatment and prevention options, the book: Provides accessible and easy to understand information as commonly asked questions and answers. Describes the changes in animal and human health when flea infestations occur. Includes practical advice pitched at a level for both owners and veterinary nurses. Top 100 Question and Answers About Fleas covers all the important facts you need to know about fleas in an easy question and answer format. Informative and interesting, it is an invaluable aid in your quest to provide the best quality of life to beloved pets.Table of Contents-: Preface 1: Basics of Fleas 2: Fleas and Pets 3: Fleas and People 4: Sorting Out Flea Problems -: Take Home Message -: Bibliography

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