Urology and urogenital medicine Books

Book SynopsisThis fully updated volume explores recently improved avenues to study urothelial carcinomas.Table of ContentsPart I: Molecular Characterization 1. Scoring Systems for Immunohistochemistry in Urothelial Carcinoma Mark-Sebastian Bösherz, Iryna V. Samarska, and Nadine Therese Gaisa 2. A Panel-Based Method for the Reproduction of Distinct Molecular Subtype Classifications of Muscle-Invasive Urothelial Bladder Cancer Csilla Olah and Tibor Szarvas 3. Analysis of Mutational Signatures Using the mutSignatures R Library Damiano Fantini and Joshua J. Meeks 4. A Drug Repurposing Pipeline Based on Bladder Cancer Integrated Proteotranscriptomics Signatures Marika Mokou, Shaman Narayanasamy, Rafael Stroggilos, Irina-Afrodita Balaur, Antonia Vlahou, Harald Mischak, and Maria Frantzi 5. Characterization of Native COMPASS Complex in Urothelial Carcinoma Cells by Size Exclusion Chromatography Christoph Peter, Wolfgang A. Schulz, and Patcharawalai Whongsiri Part II: Urothelial Carcinogenesis 6. Reconstructing Phylogenetic Relationship in Bladder Cancer: A Methodological Overview Lancelot Seillier and Martin Peifer 7. Using Sister Chromatid Exchange Assay to Detect Homologous Recombination Deficiency in Epigenetically Deregulated Urothelial Carcinoma Cells Theodoros Rampias and Apostolos Klinakis 8. Identification of STAG2 Mutant Bladder Cancers by Immunohistochemistry Youngrok Park, Alana Lelo, Brent Harris, Deborah L. Berry, Krysta Chaldekas, Jung-Sik Kim, and Todd Waldman Part III: Cellular and Animal Models 9. Genome-Wide CRISPR Screening for the Identification of Therapy-Resistance-Associated Genes in Urothelial Carcinoma Klaus Mantwill and Roman Nawroth 10. Tissue Slice Culture and Analysis of Tumor-Associated Hyaluronan in Urothelial Carcinoma William Donelan, Paul L. Crispen, and Sergei Kusmartsev Part IV: Biomarkers 11. NGS-Based Tumor-Informed Analysis of Circulating Tumor DNA Iver Nordentoft, Karin Birkenkamp-Demtröder, and Lars Dyrskjøt 12. Considering the Effects of Modern Point-of-Care Urine Biomarker Assays in Follow-Up of Patients with High-Risk Non-Muscle Invasive Bladder Cancer Thorsten H. Ecke, Natalya Benderska-Söder, Ekkehardt Bismarck, Bas W.G. van Rhijn, Tilman Todenhöfer, and Bernd J. Schmitz-Dräger 13. Simplex Droplet Digital PCR Assays for the Detection of TERT Promoter Mutations in Urine Samples for the Non-Invasive Diagnosis of Urothelial Cancer Maria Zvereva, Md Ismail Hosen, Nathalie Forey, Mahdi Sheikh, Caroline Kannengiesser, Ibrahima Ba, Arnaud Manel, Emmanuel Vian, and Florence Le Calvez-Kelm 14. Predictive Biomarkers of Response to Neoadjuvant Therapy in Muscle Invasive Bladder Cancer Jussi Nikkola and Peter Black 15. Assessment of PD-L1 Status in Urothelial Cancer Veronika Bahlinger, Arndt Hartmann, and Markus Eckstein Part V: Therapy Development 16. Epigenetic Priming and Development of New Combination Therapy Approaches Sarah Meneceur, Camilla M. Grunewald, Günter Niegisch, and Michèle. J. Hoffmann 17. Evaluation of FGFR Alteration Status in Urothelial Tumors Veronika Bahlinger, Markus Eckstein, Arndt Hartmann, and Robert Stöhr 18. Antibody-Drug-Conjugates (ADC): A Novel Treatment Option in Urothelial Carcinoma Günter Niegisch 19. Intravesical Infusion of Oncolytic Virus CG0070 in the Treatment of Bladder Cancer Paola Grandi, Andrea Darilek, Anay Moscu, Anu Pradhan, and Roger Li 20. Analysis of ICAM-1 Expression on Bladder Carcinoma Cell Lines and Infectivity and Oncolysis by Coxsackie Virus A21 Kate Relph, Mehreen Arif, Hardev Pandha, Nicola Annels, and Guy R. Simpson

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Book SynopsisSexual and Reproductive Health at a Glance provides a highly-illustrated, visual introduction to all aspects of sexual and reproductive health, from basic clinical examination skills to the management of acute Sexually Transmitted Infections (STIs) and unplanned pregnancy.Table of ContentsPreface vii Acknowledgements viii Abbreviations ix How to use your textbook xi About the companion website xii 1 Sexual and reproductive health fundamentals 2 Part 1 Principles of sexual and reproductive health 1 Part 2 Contraception 11 Part 3 Sexual health 43 2 Combined hormonal contraception 12 3 Progestogen-only contraceptives 16 4 Intrauterine contraception 22 5 Barrier methods 26 6 Fertility awareness methods 28 7 Emergency contraception 30 8 Male and female sterilization 32 9 Contraception for specific groups of individuals 36 10 Chlamydia trachomatis 44 11 Gonorrhoea and non-gonococcal urethritis 46 12 Vaginal discharge 50 13 Bacterial vaginosis 52 14 Vulvovaginal candidiasis 54 15 Trichomonas vaginalis 56 16 Syphilis 58 17 Genital herpes 64 18 Genital ulcers: tropical infections 68 19 Epididymo-orchitis and sexually-acquired reactive arthritis 72 20 Molluscum contagiosum and normal genital lumps 74 21 Anogenital warts and human papilloma virus infection 76 22 Genital infestations 80 23 Anogenital dermatoses 82 24 Viral hepatitis A, B and C 84 25 HIV 86 26 Sexual assault 90 Part 4 Reproductive health 93 27 Abortion 94 28 Abnormal uterine bleeding 100 29 Menstrual problems 102 30 Gynaecological problems in SRH 104 31 Pelvic inflammatory disease 106 32 Menopause 108 33 Sexual problems 110 Index 112

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Book SynopsisUrology Lecture Notes contains all the essential knowledge for medical students, junior doctors and early-stage trainees involved in urology placements or urological surgery. With a strong emphasis on clinical presentation, procedures and surgery, it provides an accessible, conversational guide to all the situations likely to be encountered on the wards.Key features include:Extensive illustration to clearly demonstrate relevant procedures, conditions, and physiologyImportant information flagged up in key pointsSelf-assessment MCQs to test and help consolidate knowledgeWhether you are preparing for your first urology rotation or looking for a quick reference to all aspects of the system, Urology Lecture Notes provides key support to all students, junior doctors and trainees involved in this specialty.Table of ContentsPreface vi Acknowledgements vii Part 1 Meet the patient 1 Assessment of the urological patient: History and examination 3 2 Assessment of the urological patient: Urinalysis_and imaging 17 Part 2 The kidneys and adrenal gland 3 The kidney: Embryology, developmental errors and cystic disease 33 4 Kidney trauma 45 5 Kidney infections and inflammation 50 6 Urinary tract calculi 58 7 Kidney neoplasms 73 8 The renal pelvis and ureter 92 9 The adrenal gland 110 Part 3 The bladder and urethra 10 The bladder: Structure, function and investigations 117 11 Bladder infections and inflammation 128 12 Disorders of bladder function 134 13 Bladder cancer 150 Part 4 The prostate gland 14 Benign disorders of the prostate gland 169 15 Prostate cancer 185 Part 5 Male genitalia 16 The urethra 209 17 The penis 228 18 The testicle 245 19 Male infertility 270 Part 6 Additional therapeutic modalities 20 Radiotherapy 281 21 Minimally invasive urology 285 Appendix A: ECOG performance status 294 Appendix B: TNM classification of malignant tumours 295 Appendix C: Response evaluation criteria in solid tumours 297 Appendix D: The Clavien–Dindo classification of surgical complications 300 Appendix E: Adverse effects of cancer treatment 302 Appendix F: Urinary catheters 303 Appendix G: Evidence_based medicine 308 Multiple choice questions 309 Answers 315 Index 321

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Book SynopsisABC of Sexual Health ABC of Sexual Health provides a comprehensive overview of this important, but difficult subject and includes reading resources as well as information on professional societies, patient groups and online resources. Fully revised and expanded to cover a range of new content and topics including psychological, urological, gynaecological, endocrinological and psychiatric aspects of sexual health, the effects of medication, sexual dysfunction, sexual orientation, gender identity, paraphilias, forensic sexology, dermatoses, and psychosexual therapy and education. ABC of Sexual Health is a practical guide for all general practitioners, family physicians, trainees and medical students wanting to improve communicating, examining and managing patients with sexual health problems. About the ABC series The new ABC series has been thoroughly updated, offering a fresh look, layout and features throughout, helping you to access information and deliverTable of ContentsSeries Foreword, vii Contributors, ix 1 Psychosexual Development, 1 Brian Daines 2 Physical Aspects of Sexual Development, 4 Woet L. Gianotten 3 Anatomy and Physiology in the Male, 7 Roy J. Levin 4 Anatomy and Physiology in the Female, 12 Roy J. Levin 5 The Sexual History and Formulation, 16 Julie A. Fitter 6 The Clinical Examination of Men and Women, 21 David Goldmeier 7 Male Dermatoses, 24 Manu Shah and Chris Bunker 8 Female Dermatoses, 30 Ruth Murphy 9 Investigation and Management of Endocrine Disorders Affecting Sexuality, 34 T. Hugh Jones 10 Investigations in Sexual Medicine for Women and Men with Sexual Health Problems, 38 Irwin Goldstein and Kevan Wylie 11 Definition and Diagnosis of Sexual Problems, 43 Johannes Bitzer 12 Psychiatric Disorders and Sexuality (Including Trauma and Abuse), 47 Richard Balon 13 Medication and Sexual Dysfunction, 51 John Dean 14 Problems of Sexual Desire in Men, 55 Yacov Reisman and Francesca Tripodi 15 Problems of Sexual Desire and Arousal in Women, 59 Lori A. Brotto and Ellen T.M. Laan 16 Erectile Dysfunction, 68 Geoffrey Hackett 17 Problems of Ejaculation and Orgasm in the Male, 73 Marcel D. Waldinger 18 Problems of Orgasm in the Female, 77 Sharon J. Parish 19 Sexual Pain Disorders–Male and Female, 81 Melissa A. Farmer, Seth Davis and Yitzchak M. Binik 20 Ageing and Sexuality, 86 Alison K. Wood and Ross Runciman 21 Paraphilia Behaviour and Disorders, 90 Kevan Wylie 22 Impulsive/Compulsive Sexual Behaviour, 93 Eli Coleman 23 Forensic Sexology, 96 Don Grubin 24 Ethnic and Cultural Aspects of Sexuality, 101 Sara Nasserzadeh 25 Concerns Arising from Sexual Orientation, Practices and Behaviours, 104 Dominic Davies 26 Gender Dysphoria and Transgender Health, 108 Lin Fraser and Gail A. Knudson 27 Psychosexual Therapy and Couples Therapy, 112 Trudy Hannington 28 Bibliotherapy and Internet-based Programmes for Sexual Problems, 118 Jacques van Lankveld and Fraukje E.F. Mevissen 29 Sexual Pleasure, 121 Sue Newsome Index, 125

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Book SynopsisManaging urologic cancer by preserving, as opposed to removing, affected tissue, is rapidly becoming the favoured choice for urologists and oncologists. Discover all available options and how to achieve the best possible patient management with this expert guide to the area. The editor, Mark Schoenberg, is an internationally-renown expert in this exciting new area and has recruited an outstanding team featuring some of the leading urologists/oncologists in North America and Europe to assist him.Table of ContentsList of Contributors xiii Preface xvii Cancer Genetics, Cancer Biology, and Tumor Growth and Metastasis: The Interaction of Cancer and Its Host Environment 1Mark C. Markowski and Kenneth J. Pienta Renal Cell Carcinoma 1 Bladder Cancer 3 Prostate Cancer 6 References 12 Pathological Basis of Tumor Characterization: Cytopathology, Surgical Pathology, and How Histo]Morphology Informs Treatment Decision Making 19Oleksandr N. Kryvenko and Fadi Brimo The Kidney 23 The Urothelium 27 The Testis 29 References 30 The Immunobiology of Tumor Ablation 33Rafi Kabarriti and Chandan Guha Manipulating the Immune System to Fight Cancer 33 Can We Take Advantage of Ablative Therapies to Activate the Immune System? 34 Immunomodulatory Properties of HIFU 35 Immunomodulatory Properties of Cryotherapy 36 Immunomodulatory Properties of Radiation Therapy 37 References 38 Computed Tomography of Urologic Malignancies: The Role of MDCT in Renal Cell Carcinoma and Transitional Cell Carcinoma 41Siva P. Raman and Elliot K. Fishman Introduction 41 MDCT Protocol Design 41 Three]Dimensional Reconstructions 44 Neoplasms of the Intrarenal Collecting Systems, Ureters, and Bladder 45 Solid Renal Parenchymal Lesions 49 Conclusion 55 References 55 MRI and Metabolic Imaging 59Louise Dickinson, Francesco Fraioli, Athar Haroon, and Clare Allen Magnetic Resonance Imaging 59 MRI Sequences 59 Clinical Applications of MRI for Prostate Cancer 61 Clinical Applications of MRI for Renal Cancer 63 Clinical Applications of MRI for Bladder Cancer 64 New Advances in MRI 65 Metabolic Imaging 66 Clinical Applications of PET–CT for Prostate Cancer 69 Active Surveillance for Low]Risk Prostate Cancer 113Laurence Klotz Introduction and Background 113 Rationale 113 Genetic Features of Low]Grade Prostate Cancer 114 Metastatic Potential 115 Limitations of PSA Kinetics 116 Role of MRI 116 Implications for Patient Management 117 Eligibility for Surveillance 118 Outcome of Surveillance 119 Modeling 119 AS in Practice 121 Conclusions 121 References 122 Tissue]Preserving Surgical Approaches in Urologic Oncology: The Therapeutic Mechanism for Tumor Ablation 127Ganesh Kartha and J. Stephen Jones Introduction 127 Cryoablation: Extreme Cold for Tumor Necrosis 128 Conclusion 130 References 130 Focal Therapy for Prostate Cancer: An Evidence]Based Approach to Tissue]Preserving Strategies 133Kara L. Watts, Yaalini Shanmugabavan, Victoria Chernyak, and Hashim Uddin Ahmed Introduction 133 Key Concepts in FT for PCa 134 Tissue]Preserving FTs 135 Cryotherapy 135 HIFU 137 Salvage Focal/Hemiablation HIFU 140 IRE 141 Radiation 142 Additional Therapies 143 Implications for Research 144 Conclusions 144 References 145 The Modern Basis for Nephron]Sparing Surgery in Patients with Renal Cancer: Biologic Heterogeneity, the Significance of Tumor Biopsy, and the Changing Roles of Partial Nephrectomy and Tumor Ablation 151Jeffrey J. Tomaszewski, Robert G. Uzzo, and David Y.T. Chen Introduction 151 Principal Treatment Options for SRMs and the Basis for Nephron Preservation 152 Comparative Effectiveness of Radical versus NSS 153 Rationale for Ablative Therapies 154 Treatment Trends for Stage I RCC 157 The Role of RMB 158 Challenges Posed by Intratumoral Heterogeneity 161 Conclusions 161 References 162 Bladder]Preserving Strategies in the Treatment of Urothelial Cancer: The Disease Spectrum and the Dawn of Molecular Surgical Guidance 169Stephan Kruck and Arnulf Stenzl Augmented Cystoscopy 170 Fiber]Optic Probe Technology 171 Conclusion 172 References 172 Image]Guided Thermal Ablation of Adrenal Malignancies 175Kyungmouk Steve Lee, Bradley B. Pua, and Stephen B. Solomon Introduction 175 Clinical Results 175 Preprocedural Evaluation 176 Technical Considerations 178 RFA 178 Microwave Ablation 179 Cryoablation 180 Complications 180 Follow]up 181 Conclusion 182 References 182 Managing Penile Cancer: Integrating Tissue Preservation, Energy]Based Therapeutics, and Surgical Reconstruction 185Arthur L. Burnett Introduction 185 Description 186 Diagnosis and Staging 186 Treatment 189 References 193 Testis Cancer: Testis]Sparing Cancer Surgery 199Nilay M. Gandhi and Pravin K. Rao Introduction 199 Imaging of Testicular Tumors 199 Bilateral Tumors 201 The Advent of Testis]Sparing Surgery 201 Concerns about TSS 201 Indications for TSS 204 Preoperative Considerations and Surgical Technique 204 Postoperative Care and Follow]Up 207 Considerations Regarding Surgical Technique 207 Outcomes of TSS 208 Summary 209 References 210 Nanotechnology: An Evolution in Tissue Preservation and Focal]Targeted Oncologic Therapy 213Kara L. Watts and Joshua M. Stern Introduction 213 Introduction to Nanotechnology 214 Types of Nanoparticles 214 Delivery and Use of Nanoparticles 217 Nanotechnology in Prostate Cancer 219 Imaging in Prostate Cancer 219 Therapeutics in Prostate Cancer 221 Nanotechnology in Renal Cancer 223 Nanotechnology in Other Urologic Cancers 224 Limitations of Nanoparticles 224 Future Directions and Conclusions 225 References 226 Trial Design Issues in the Study of Focal Therapy in Prostate and Kidney Cancer 233John B. Eifler and David F. Penson Issues around Endpoints in Studies of Focal Therapy 234 Issues around Defining the Study Population and the Control Arms of Comparative Studies in Focal Therapy 237 Issues around Selecting the Optimal Study Design in Focal Therapy 238 Conclusion 238 References 239 Index 000

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Book SynopsisA Clinical Guide to Urologic Emergencies A Clinical Guide to Urologic EmergenciesAn ageing population and a predicted shortfall in the number of urologists means that, increasingly, the management of complex urological problems will fall to hospital emergency departments and the surgeries of primary care physicians. With many doctors and medical students now having less exposure to urology, there is a real and urgent need for accessible and practical guidance in managing urologic emergencies. A Clinical Guide to Urologic Emergencies offers practical guidance to the best practices in diagnosis, treatment and management of patients with urgent urological conditions. Designed to be an extremely useful tool to consult in the clinical setting, it will be a vital source of information and guidance for all clinicians, irrespective of their level of urologic knowledge. Edited by an outstanding international editor team, this book is particularly aimed at physicians, advanced practice proviTable of ContentsContributors Preface SECTION 1 Upper Urinary Tract 1 Blunt Renal Injuries Lindsay Hampson and Nnenaya Mmonu 2 Penetrating Renal Trauma – A Civilian and Military Perspective Jonathan Wingate 3 Renal Infections Brusabhanu Nayak, Nitin Srivastava, and Rajeev Kumar 4 Acute Kidney Stone Management Justin S. Ahn and Jonathan D. Harper 5 Traumatic Adrenal Hemorrhage Hong Truong and Bradley D. Figler 6 External Ureteral Trauma Humberto G. Villarreal and Steven J. Hudak 7 Iatrogenic Ureteral injury Haruaki Kato, Kazuyoshi Iijima, Tomohiko Oguchi, Seiji Yano SECTION 2 Lower Urinary Tract 8 Bladder Injuries Yosuke Nakajima 9 TRAUMATIC URETHRAL INJURIES Laura G. Velarde and Reynaldo G. Gómez 10 Acute management of urethral stricture Akio Horiguchi 11 PROSTATITIS AND PROSTATIC ABSCESS Hunter Wessells SECTION 3 External Genitalia 12 Fournier’s Gangrene Kosuke Kitamura and Shigeo Horie 13 Traumatic Penile Injuries Ariel Fredrick and Alex J. Vann 14 Priapism Akash A. Kapadia, Kevin Ostrowski and Thomas J. Walsh 15 Traumatic Scrotal and Testicular Injuries Marios Hadjipavlou and Davendra Sharm 16 Testicular Torsion Alexander J. Skokan and Dana A. Weiss 17 Epididymitis and Orchitis Norman Zambrano SECTION 4 Pediatric 18 Urologic Neonatal Emergencies Nicolas Fernandez and Nayib Fakih Index

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Book SynopsisThe most comprehensive textbook in the field edited by the founding father of endourology returns for a new edition. In full colour throughout and packed with surgical teaching videos, this is an essential purchase for all urologists wishing to master their skills.Table of ContentsList of Contributors Foreword Preface About the Companion Website Volume 1 Section 1 Basic Principles 1 Care and Sterilization of InstrumentsCarol Olsen 2 Radiation Safety During Diagnosis and TreatmentYasser A. Noureldin & Sero Andonian 3 Enhanced Endoscopic ImagingGhalib A. Jibara & Michael E. Lipkin 4 Preoperative Antibiotics and Prevention of Sepsis in Urologic Endoscopic SurgeryManish N. Patel & Jorge Gutierrez-Aceves 5 Management of the Anticoagulated PatientZeph Okeke Section 2 Percutaneous Renal Surgery Part 1 Perioperative Considerations 6 Surgical Anatomy of the Kidney for Endourological ProceduresFrancisco J.B. Sampaio 7 Nephrolithometric Scoring Systems for Percutaneous NephrolithotomyRoshan Patel, Daniel J. Lama, & Zhamshid Okhunov 8 Pathophysiology of Urinary Tract ObstructionFrederick A. Gulmi & Diane Felsen 9 Organizing the Endourological Operating RoomRavindra B. Sabnis, Abhishek Singh, & Shashikant Mishra 10 Endoscopic Training/SimulationZichen Zhao & Robert M. Sweet Part 2 Patient Positioning for Percutaneous Access 11 Patient Positioning, the Supine Position, and the Rationale of ECIRSCesare M. Scoffone & Cecilia M. Cracco 12 Prone, Lateral, and Flexed: Patient Positioning for Percutaneous NephrolithotomyRobert J. Sowerby, A. Andrew Ray, & R. John D’A. Honey Part 3 Imaging for Access 13 Percutaneous Nephrolithotomy Access Under Fluoroscopic ControlNorberto O. Bernardo & Maximiliano Lopez Silva 14 Dyna-CT-Guided versus Standard CT-Guided Renal AccessManuel Ritter & Maurice-Stephan Michel 15 Endoscopically Guided Percutaneous Renal AccessZhamshid Okhunov, Kamaljot S. Kaler, Simone Vernez, Rahul Dutta, Jaime Landman, & Ralph V. Clayman 16 Percutaneous Nephrolithotomy Access Under UltrasoundMahesh R. Desai & Arvind P. Ganpule 17 New Concepts of Renal Access: iPad, GPS, and OthersEstevao Lima, Pedro L. Rodrigues, Marie-Claire Rassweiler-Seyfried, & Joao L. Vilaca Part 4 Selection of Access and Dilation 18 Percutaneous Nephrolithotomy: Upper Pole AccessDavis P. Viprakasit & Nicole L. Miller 19 Percutaneous Nephrolithotomy Access Without Image GuidanceArthur D. Smith 20 Percutaneous Nephrolithotomy Access: RoboticMichelle Jo Semins, Dan Stoianovici, & Brian R. Matlaga 21 Dilation of the Nephrostomy TractPeter Alken Part 5 Stone Removal 22 Rigid and Flexible NephroscopyTimothy Y. Tran & Mantu Gupta 23 Percutaneous Antegrade UreteroscopyBurak Turna, Umit Eskidemir, & Oktay Nazli 24 Small-caliber Percutaneous Nephrolithotomy: Mini, UMP, and Micro-PercJanak D. Desai & Arkadiusz Miernik 25 Percutaneous Nephrolithotomy: Special Problems with StaghornsMonica A. Farcas & Kenneth T. Pace 26 Percutaneous Nephrolithotomy: Stone Extraction and LithotripsySamir Derisavifard & Arthur D. Smith 27 Percutaneous Nephrolithotomy in ChildrenAdam S. Howe, Jordan S. Gitlin, & R. John D’A. Honey Part 6 Other Uses of Nephrostomy Access 28 Percutaneous Nephrolithotomy of Calyceal Diverticula, Infundibular Stenosis, and Simple CystsNadya E. York & James E. Lingeman 29 Percutaneous Instillation of Chemolytic, Chemotherapeutic, and Antifungal AgentsMohamed A. Elkoushy, Philippe D. Violette, & Sero Andonian 30 Percutaneous Treatment of Ureteropelvic Junction ObstructionMichael W. Sourial, Bodo E. Knudsen, & Paul J. Van Cangh 31 Percutaneous Management of Upper Tract Urothelial CarcinomaShu Pan & Piruz Motamedinia Part 7 Exit Strategy and Complications 32 The Access-related Complications of Percutaneous NephrolithotomyVinaya Vasudevan, Zeph Okeke, & Arthur D. Smith 33 Hemorrhagic Complications Associated with Percutaneous NephrolithotomySriram V. Eleswarapu & David A. Leavitt 34 Diagnosis and Management of Thoracic Complications of Percutaneous Renal SurgeryJohn R. Bell & Stephen Y. Nakada 35 Bowel and Other Organ Injuries with Percutaneous NephrolithotomyJohn J. Knoedler, Matthew T. Gettman, & Chad J. Fleming 36 Exit Strategies After Percutaneous NephrolithotomyDamien M. Bolton & Derek B. Hennessey 37 Problems with Residual StonesNoah E. Canvasser & Margaret S. Pearle Section 3 Ureteroscopy Part 1 General Principles 38 Ureteral AnatomyGary Faerber, Amir H. Lebastchi, & Rita P. Jen 39 Rigid UreteroscopesOmar M. Aboumarzouk & Francis X. Keeley, Jr. 40 Flexible UreteroscopesVincent G. Bird & John M. Shields 41 Rigid Ureteroscope with Flexible Tip and Special InstrumentationYinghao Sun & Xiaofeng Gao 42 Digital UreteroscopesMurat Binbay & Burak Ucpinar 43 Ureteroscopy Working InstrumentsRenato N. Pedro & Manoj Monga 44 Access to the Ureter: Rigid UreteroscopyJose De La Cerda, III & Timothy Y. Tseng 45 Access to the Ureter: Flexible UreteroscopyOjas Shah & Mark V. Silva 46 Ureteroscopy Energy SourcesDaniel A. Wollin & Glenn M. Preminger 47 Ureteroscopic Management of Ureteral CalculiCharles U. Nottingham, Melanie A. Adamsky, Richard J. Fantus, & Glenn S. Gerber 48 Ureteroscopic Management of Renal CalculiSteeve Doizi & Olivier Traxer 49 Diagnostic UreteroscopyHendrik Heers & Benjamin W. Turney 50 Ureteroscopic Diagnosis and Treatment of Upper Urinary Tract NeoplasmsScott G. Hubosky & Demetrius H. Bagley Part 2 Ureteroscopic Management of Ureteral Obstruction 51 Retrograde EndopyelotomyWeil R. Lai & Raju Thomas 52 Endoscopic Management of Mid-ureteral ObstructionSamuel Abourbih & D. Duane Baldwin 53 Endoscopic Management of Distal Ureteral StricturesMichael Zhang, Ali Fathollahi, Joel Hillesohn, & Majid Eshghi 54 Endoscopic Management of Ureteroenteric StricturesThomas Masterson & Robert Marcovich 55 Ureterorenoscopy: Ureteral Stents and Postoperative CareBen H. Chew, Anthony Emmott, Dirk Lange, & Ryan F. Paterson 56 Ureteroscopy ComplicationsJoel E. Abbott & Roger L. Sur 57 Retrograde Intrarenal Surgery in the Future: RoboticsAnup Patel Section 4 Shock-Wave Lithotripsy 58 Physics of Shock-wave LithotripsyAndreas Neisius & Pei Zhong 59 Lithotripsy SystemsGeert G. Tailly 60 Shock-wave Lithotripsy of Renal CalculiBrian H. Eisner & Naren Nimmagadda 61 Shock-wave Lithotripsy of Ureteral CalculiThomas Tailly & Hassan Razvi 62 Complications of Shock-wave LithotripsyChristian Turk & Aleš Petřik Section 5 Stone Management in Urology Part 1 General Principles 63 Natural History of StonesJohann P. Ingimarsson & Amy E. Krambeck 64 Initial Choice of Therapy in the Stone PatientPeter L. Steinberg & David M. Hoenig 65 Management of Urolithiasis in PregnancyHusain Alenezi & John D. Denstedt 66 Management of Renal Colic and Triage in the Emergency DepartmentMarius C. Conradie Part 2 Management of Stones in Abnormal Situations 67 Management of Stones in Horseshoe KidneysChandra Shekhar Biyani & Adrian D. Joyce 68 Pelvic KidneysWin Shun Lai, Vidhush K. Yarlagadda, & Dean G. Assimos 69 Management of Stone Disease in Renal Transplant KidneysBrian Duty & Michael Lam 70 Stones in Urinary DiversionsBodo E. Knudsen & Michael W. Sourial 71 Management of Stones in ObesityOmer L. Tuncay & Cenk Acar Part 3 Cost-effectiveness and Long-term Stenting 72 Cost-effective Strategies for Stone ManagementJustin I. Friedlander & Eric M. Ghiraldi 73 Long-term Stenting of the UreterPanagiotis Kallidonis, Wissam Kamal, Dimitrios Kotsiris, Dimitrios Karnabatidis, & Evangelos Liatsikos Volume 2 Section 6 Laparoscopy and Robotic Surgery Part 1 General Principles 74 New Surgical RoboticsAlabdulaali Ibrahim & Koon Ho Rha 75 Training and Credentialing Laparoscopic and Robotic SurgeryDomenico Veneziano & David M. Hananel 76 Patient Preparation and Operating Room Setup for Laparoscopic and Robotic SurgeryWeil R. Lai & Benjamin R. Lee 77 Patient Preparation and Operating Room Setup for Robotic SurgeryDima Raskolnikov, Mahir Maruf, & Arvin K. George 78 Physiologic Considerations in Laparoscopic and Robotic SurgeryAdam G. Kaplan & Michael N. Ferrandino 79 Anesthetic Management During Laparoscopic/Robotic SurgeryJudith Aronsohn, Oonagh Dowling, & Greg Palleschi Part 2 Instrumentation, Access, and Exit 80 Laparoscopic Surgery: Basic InstrumentationOrnob Roy 81 Robotic Surgery: Basic Instrumentation and TroubleshootingWooju Jeong, Mouafak Tourojman, & Craig G. Rogers 82 Minimally Invasive Reconstructive Techniques: Suture, Staple, and Clip TechnologyAli Abdel Raheem & Koon Ho Rha 83 Transperitoneal Access and Trocar PlacementAngelo Territo & Alberto Breda 84 Retroperitoneal Access and Trocar PlacementLambros Stamatakis & Soroush Rais-Bahrami 85 Basic Hand-assisted Laparoscopic TechniquesSapan N. Ambani & J. Stuart Wolf, Jr. 86 Laparoscopic Exit: Specimen Removal, Closure, and DrainageFernando J. Kim, Riccardo Autorino, & Rodrigo Donalisio da Silva Part 3 Complications 87 Complications in Urologic LaparoscopyDavid Canes, Camilo Giedelman, & Rene J. Sotelo 88 Complications of Laparoscopy Including RoboticsFriedrich-Carl von Rundstedt, Marcelo Chen, & Richard E. Link Part 4 Laparoscopy/Robotics for Malignant Disease 89 Pelvic LymphadenectomyMarc D. Manganiello & Andrew A. Wagner 90 Endoscopic Subcutaneous Modified Inguinal Lymph Node Dissection for Squamous Cell Carcinoma of the PenisJay T. Bishoff & Kefu Du 91 Laparoscopic and Robotic Retroperitoneal Lymph Node DissectionJames R. Porter 92 Laparoscopic Radical NephrectomySimpa S. Salami 93 Robotic Partial Nephrectomy: Advancements and InnovationsSameer Chopra, Mehar Bains, & Inderbir S. Gill 94 Intraoperative Assessment of Tumor Resection MarginsIlan Z. Kafka & Timothy D. Averch 95 Laparoscopic Radical NephroureterectomyWayland J. Wu & Jessica E. Kreshover 96 Laparoscopic and Robotic Radical Cystectomy in Males and FemalesDouglas S. Scherr, David M. Golombos, & Abimbola Ayangbesan 97 Robot-assisted Laparoscopic Partial CystectomyManish A. Vira & Paras H. Shah 98 Laparoscopic Cystoprostatectomy with Intracorporeal Ileal ConduitAlvin C. Goh, Brian J. Miles, & Arun Rai 99 Laparoscopic/Robotic Continent DiversionChristopher R. Reynolds & Ashok K. Hemal 100 Laparoscopic Radical ProstatectomyJens Rassweiler, Giovannalberto Pini, Marcel Fiedler, Ali Serdar Goezen, & Dogu Teber 101 Robot-assisted Laparoscopic Radical ProstatectomyZeyad Schwen & Misop Han 102 Optimizing Outcomes During Laparoscopic and Robot-assisted Radical ProstatectomyMatthew Goland-Van Ryn, Daniel Rosen, Thomas Bessede, & Ashutosh Tewari Part 5 Laparoscopy/Robotics for Benign Disease 103 Laparoscopic and Robotic Reconstructive Ureteral Surgery: Basic PrinciplesAaron C. Weinberg, Yuka Yamaguchi, Lee C. Zhao, & Michael D. Stifelman 104 Laparoscopic Applications to Renal Calculus DiseaseChristopher S. Han & Sammy E. Elsamra 105 Laparoscopic Treatment of Renal Cysts and DiverticulaSalvatore Micali, Eugenio Martorana, Giacomo Maria Pirola, & Giampaolo Bianchi 106 Laparoscopic and Robotic Techniques for Management of Pelvic Organ ProlapseSandeep Gurram & Farzeen Firoozi 107 Laparoscopic and Robotic Techniques for Repair of Female Genitourinary FistulasChad Baxter & Vishnukamal Golla 108 Laparoscopic, Laparoendoscopic Single-site, and Robot-assisted Living Donor NephrectomyGanesh Sivarajan & Ravi Munver 109 Robotic Kidney TransplantationRajesh Ahlawat, Sohrab Arora, & Mani Menon 110 Minimally Invasive Surgery for Benign Prostate Disease: Laparoscopic and Robotic TechniquesMark Ferretti, Amul Bhalodi, & John Phillips 111 Laparoscopic AdrenalectomyTadashi Matsuda, Hidefumi Kinoshita, Yoshihide Kawasaki, & Akira Miyajima 112 Laparoscopic and Robotic Surgery of the Seminal VesiclesEric H. Kim, R. Sherburne Figenshau, & Gerald L. Andriole 113 Modern Techniques in Abdominal Wall Hernia Repair: a Guide for the Practicing EndourologistDouglas K. Held 114 Robot-assisted Vasectomy ReversalParviz K. Kavoussi Part 6 Laparoscopy/Robotics in Children 115 Laparoscopic Considerations in ChildrenRajeev Chaudhry, Michelle Yu, & Michael C. Ost 116 Laparoscopic and Robotic Pyeloplasty in ChildrenKai-wen Chuang 117 Lower Ureteral Reconstruction: Robotic SurgeryS. Duke Herrell 118 Laparoscopic Management of the Undescended TesticleBrian A. VanderBrink 119 Laparoscopic VaricocelectomyBradley A. Morganstern & Lane S. Palmer Part 7 Laparoscopy and Robotics: LESS and NOTES 120 Laparoendoscopic Single-site Surgery: Ports, Access, and InstrumentationNoah E. Canvasser & Jeffrey A. Cadeddu 121 Laparoendoscopic Single-site Upper Tract SurgeryChristian Tabib, Geoffrey Gaunay, & Lee Richstone 122 Robotic Laparoendoscopic Single-site Lower Tract SurgeryDaniel Ramirez, Matthew J. Maurice, & Jihad H. Kaouk Section 7 Image-Guided Diagnostics and Therapeutics Part 1 Upper Tract 123 Diagnosis of Renal Masses: RadiologicalGail S. Smith, Carolyn K. Donaldson, & Richard M. Gore 124 Renal Mass BiopsyM. Pilar Laguna & Jean de la Rosette 125 Radiofrequency Ablation of Renal TumorsRyan L. Steinberg & Chad R. Tracy 126 Percutaneous Cryoablation of Renal MassesDavid N. Siegel & Alok A. Anand Part 2 Angio-embolization in Urology 127 Gonadal Vein EmbolizationPratik A. Shukla, Gajan Sivananthan, & Ardeshir R. Rastinehad 128 Renal Angiography and EmbolizationIgor Lobko & Anthony D. Mohabir 129 Selective Arterial Prostate EmbolizationRobert C. Blue, Aaron M. Fischman, & Ardeshir R. Rastinehad Part 3 Focal Therapy Lower Tract 130 The Role and Methodology of Multiparametric MRI and Fusion-guided Biopsy in the Management of Prostate Cancer PatientsRaju R. Chelluri, Arvin K. George, Joseph A. Baiocco, Baris Turkbey, & Peter A. Pinto 131 Focal Therapy of Prostate CancerKae Jack Tay & Thomas J. Polascik 132 Focal Laser Ablation for Carcinoma of ProstateTonye A. Jones, Shyam Natarajan, & Leonard S. Marks 133 Image-guided Prostate BrachytherapyMichael R. Folkert, Neil B. Desai, & Yoshiya Yamada 134 Image-guided External Beam RadiotherapyBrett Cox, Lucille Lee, & Louis Potters 135 High-intensity Focused Ultrasound of the ProstateEdward J. Bass, Mark Emberton, & Hashim U. Ahmed 136 Cryotherapy of the ProstateDaniel B. Rukstalis 137 Cryosurgical Ablation of the ProstateRajan Ramanathan, Yaw A. Nyame, & J. Stephen Jones 138 Contrast-enhanced Ultrasound in UrologyRogier R. Wildeboer, Jean de la Rosette, Massimo Mischi, & Hessel Wijkstra 139 Principles of Prostate Magnetic Resonance ImagingSonia Gaur, Baris Turkbey, & Peter L. Choyke 140 Male Lower Urinary Tract Symptoms and AssessmentHenry Tran, Matthew P. Rutman, Doreen E. Chung, & Jerry G. Blaivas 141 Office-based Cystoscopy: Continued AdvancesJudson D. Davies & Sam S. Chang 142 Equipment Setup and Patient HandoutsJohn R. Schwabe, Amanda P. Hughes, Crystal R. Combs, & Gopal H. Badlani 143 Local Anesthesia for Minimally Invasive Treatment of the Prostate in the Office SettingArun Rai & Ricardo R. Gonzalez 144 Laser in Benign Prostatic Hyperplasia Treatment: Basic PrinciplesChristopher Netsch, Bilal Chughtai, Alexis E. Te, Ahmed M. Elshal, Mostafa M. Elhilali, & Andreas J. Gross 145 Holmium Laser Therapy of the ProstateAhmed M. Elshal & Mostafa M. Elhilali 146 532 nm High-power Transurethral Laser ProstatectomyBilal Chughtai, Dominique Thomas, & Alexis E. Te 147 Thulium LasersAndreas J. Gross & Christopher Netsch 148 The Prostatic Urethral Lift Procedure Using UroLift Implants: Novel, Minimally Invasive Therapy for Benign Prostatic HyperplasiaDaniel B. Rukstalis 149 Goals and Expectations of Ablation Techniques and Emerging Therapies for Benign Prostatic Hyperplasia: An EditorialCatriona I. MacRae & Peter J. Gilling 150 Monopolar Transurethral Resection of ProstateMadhu S. Agrawal & Dilip K. Mishra 151 Ablation of Prostate: Bipolar ResectionJaspreet S. Sandhu 152 Bipolar Vaporization of the ProstateAhmet Karakeci, Kyle Richards, & Gopal H. Badlani 153 Single Port for Prostate SurgeryRene J. Sotelo, Oscar D. Martin Garzon, Camilo Giedelman, Fatima Z. Husain, & Mihir Desai 154 Bladder Injections for Refractory Overactive Bladder: Intra- and Transvesical ProceduresAdam Althaus & Anurag K. Das 155 STING Procedure for RefluxSteve J. Hodges 156 Minimally Invasive Therapy for Bladder Pain Syndrome (Interstitial Cystitis)Ricardo Palmerola, Sandeep Gurram, & Robert Moldwin 157 New Techniques for Resecting Bladder TumorsAlexey G. Martov, Dmitry V. Ergakov, Nikolay A. Baykov, & Zhamshid Okhunov 158 Incision: Endoscopic Management of Urethral StenosesGerald H. Jordan & Kurt A. McCammon 159 Endoscopic Management of Bladder Neck Contracture Following Radical ProstatectomySusan MacDonald, R. Caleb Kovell, Joseph Tortora, & Ryan P. Terlecki 160 Single-incision SlingsMichael J. Kennelly & Dina A. Bastawros 161 Bioinjectables for Stress Urinary IncontinenceRyan Dobbs, Simone Crivellaro, & John J. Smith III 162 Midurethral Slings for the Treatment of Female Stress Urinary IncontinenceAlice Drain & Victor W. Nitti 163 Maxi/Pubovaginal SlingGopal H. Badlani & Joao P. Zambon 164 Mesh Complications Associated with Vaginal Prolapse SurgeryJeffrey S. Schachar & G. Willy Davila 165 Male Slings for Treatment of Post-prostatectomy IncontinenceAjay K. Singla & Nirmish Singla 166 NeuromodulationDayron Rodriguez & Anurag K. Das Index

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Book SynopsisEffective problem-solving approach using cases actually encountered in clinical practice!.Table of ContentsList of Contributors. Preface. 1 Pediatric Nephrology. 2 Perinatal Urology. 3 Urodynamics. 4 Hypospadias and Related Conditions. 5 Testicular disorders. 6 Epispadias, Bladder and Cloacal Exstrophy. 7 Vesicoureteric Reflux. 8 Congenital Anomalies- Kidney and Ureter. 9 Congenital Anomalies- Bladder and Urethra. 10 Genitourinary Trauma. 11 Office Pediatric Urology. 12 Neuropathic Bladder and Bowel. 13 Pediatric Urinary Stone Disease. 14 Genitourinary Tumours. 15 Female Genital Anomalies. 16 Urinary Tract Infections. 17 Ambiguous Genetalia and Intersex Disorders. Index.

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Book SynopsisThe new international standard reference work for sexual medicine * Written under the auspices of the International Society for Sexual Medicine, (www. issm.Table of ContentsList of contributors. Preface. Foreword. 1. Preclinical Research and Animal Models in Sexual Medicine. François Giuliano, Kevin McKenna, Balasubramanian Srilatha, James G. Pfaus. 2. Psychologic and Interpersonal Aspects and their Management. Stanley E. Althof, Raymond Rosen, Eusebio Rubio-Aurioles, Carolyn Earle, Marie Chevret-Measson. 3. Anatomy and Physiology of Erection. Hartmut Porst, Ira D. Sharlip. 4. History and Epidemiology of Male Sexual Dysfunction. Hartmut Porst, Ira D. Sharlip. 5. Etiology and Risk Factors of Erectile Dysfunction. Hussein Ghanem, Hartmut Porst. 6. Diagnosis of Erectile Dysfunction. Allen D. Seftel. 7. Oral Pharmacotherapy of Erectile Dysfunction. Hartmut Porst. 8. Self-Injection, Trans-Urethral and Topical Therapy in Erectile Dysfunction. Hartmut Porst, Ganesan Adaikan. 9. Future Aspects of Pharmacotherapy in Erectile Dysfunction. Hartmut Porst. 10. Future Treatment Aspects of Erectile Dysfunction: Gene Therapy and Tissue. Engineering. Wayne J.G. Hellstrom. 11. Vacuum Constriction Devices. Sidney Glina, Hartmut Porst. 12. Surgical Treatment of Erectile Dysfunction. Vascular Surgery of the Penis. Michael Sohn. Penile Prosthetic Surgery. Michael Sohn, Antonio Martín-Morales. 13. Hypoactive Sexual Desire in Men. Eusebio Rubio-Aurioles. 14. Peyronie’s Disease. Pathophysiology and Medical Management. Ajay Nehra. Surgical Treatment of Peyronie’s Disease. John Mulhall. 15. Priapism. Pathophysiology and Non-Surgical Management. Ajay Nehra. Surgical Management of Priapism. John Mulhall. 16. Ejaculatory Disorders. Chris G. McMahon, Marcel Waldinger, David Rowland, Pierre Assalian, Young Chan Kim, Amado Bechara, Alan Riley. 17. Radical Pelvic Surgery-Associated Sexual Dysfunction. John Mulhall, Sidney Glina. 18. Hormones, Metabolism, Aging and Men’s Health. Jacques Buvat, Ridwan Shabsigh, André Guay, Louis Gooren, Luiz Otavio Torres,. Eric Meuleman. Introduction to Female Sexual Disorders. Alessandra Graziottin. 19. Anatomy and Physiology of Women’s Sexual Function. Alessandra Graziottin, Annamaria Giraldi. 20. Classification, Etiology, and Key Issues in Female Sexual Disorders. Alessandra Graziottin, Lorraine Dennerstein, Jeanne L. Alexander, Annamaria Giraldi, Beverly Whipple. 21. Sexual Desire Disorders in Women. Lorraine Dennerstein, Jeanne L. Alexander, Alessandra Graziottin. 22. Sexual Aversion Disorders in Women. Linda Banner, Beverly Whipple, Alessandra Graziottin. 23. Sexual Arousal Disorders in Women. Annamaria Giraldi, Alessandra Graziottin. 24. Orgasmic Disorders in Women. Beverly Whipple, Alessandra Graziottin. 25. Sexual Pain Disorders: Dyspareunia and Vaginismus. Alessandra Graziottin. 26. Iatrogenic and Post-Traumatic Female Sexual Disorder. Alessandra Graziottin. 27. Hormonal Therapy after Menopause. Alessandra Graziottin. Female Sexual Disorders: Future Trends and Conclusions. Alessandra Graziottin, Beverly Whipple, Lorraine Dennerstein, Jeanne L. Alexander, Linda Banner, Annamaria Giraldi. 28. Cardiovascular Issues in Male and Female Sexual Dysfunction. Graham Jackson, Adolph Hutter. Index

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Book SynopsisThis book comprehensively reviews the potential of focal therapy and discusses why the changing face of prostate cancer warrants a change in the way we treat men with the disease. It deals with the mechanisms by which disease can be localized within the gland and then the different technologies used for focal ablation.Trade Review“Whilst the book is not designed to represent a daily reference guide for the majority of the urological fraternity, it clearly does what it sets out to do; provide an up-to-date and comprehensive analysis of a treatment option that perhaps one day we will routinely consider alongside active surveillance and robotic surgery.” (Urology News, 1 November 2012)Fokaltherapie bedeutet Heilung und Organerhalt bei Männern mit lokal begrenztem Prostatakarzinom. Von einem internationalen Team führender Urologen, Onkologen, Radiologen und Pathologen geschrieben, bietet dieses Handbuch einen umfassenden evidenzbasierten Überblick über diese aufsehenerregende neue Therapieform.Table of ContentsContributor List, vii Preface, xi Section I Is there a role for Focal Therapy in Localised Prostate Cancer?, 1 1 The Rationale for Focal Therapy of Prostate Cancer, 3 Cole Davis, Matthew Cooperberg, and Peter R. Carroll 2 Factors That Affect Patients' Choice of Treatment, 11 Deb Feldman-Stewart and Michael D. Brundage 3 Histological Trends and the Index Lesion in Localized Prostate Cancer, 17 Vladimir Mouraviev, Thomas Wheeler, and Thomas J. Polascik 4 Selection Criteria for Prostate Cancer Focal Therapy, 29 Rajat K. Jain, Timothy K. Ito, and Samir S. Taneja Section II How can we accurately locate cancer within the gland?, 37 5 Localisation of Cancer within the Gland: Biopsy Strategies, 39 Winston E Barzell and Rodrigo Pinochet 6 Localisation of Cancer within the Gland: Ultrasound Imaging, 47 Ulrich Scheipers 7 Localization of Cancer within the Prostate: Dynamic Contrast-Enhanced MRI, 55 Philippe Puech, Anwar Padhani, Laurent Lemaitre, Nacim Betrouni, Pierre Colin, and Arnauld Villers 8 Localization of Cancer within the Gland: Diffusion-Weighted Magnetic Resonance Imaging of the Prostate, 66 Sophie F Riches, Nina Tunariu, and Nandita M deSouza 9 The future of Molecular and Biomolecular Imaging in Prostate Cancer, 75 Michael S. Gee and Mukesh G. Harisinghani Section III How can we create discrete tissue necrosis?, 85 10 Energies for Focal Ablation: Cryoablation, 87 John F. Ward 11 Focal Salvage Cryoablation in Recurrent Prostate Cancer, 98 Katsuto Shinohara 12 High-Intensity Focused Ultrasound, 106 Hashim Uddin Ahmed and Mark Emberton 13 Energies for Focal Ablation: Photodynamic Therapy, 114 Caroline M. Moore, Nimalan Arumainayagam and Mark Emberton 14 Focal Therapy for Prostate Cancer Using Radiation, 126 Irving Kaplan, Elizabeth Genega and Neil Rofsky 15 Image Registration and Fusion for Image-Guided Focal Ablation, 132 Dean Barratt and David Hawkes Section IV How can we determine the success of Focal Therapy? , 143 16 Determining Success of Focal Therapy: Biochemical and Biopsy Strategies, 145 Al Barqawi, Paul Maroni, and David Crawford 17 Determining Success of Focal Therapy: Imaging, 153 Alex Kirkham and Clare Allen 18 Evaluating Focal Therapy: Future Perspectives, 170 Hashim Uddin Ahmed and Mark Emberton Index, 179 Colour plate section can be found facing page 116

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Book SynopsisA Woman's Guide to Pelvic Health encourages women to address their pelvic floor issues and reclaim their lives.Trade ReviewThe authors combine an upbeat, positive tone with detailed, understandable descriptions of pelvic floor disorders and treatment options. Highly recommended for any woman suffering from one of these disorders. Library JournalTable of ContentsForeword, by Jill Grimes, M.D.AcknowledgmentsChapter 1. Anatomy and Pelvic Floor HealthIs This You?What's Happening with Your Pelvic Floor?What Is Your Pelvic Floor IQ?Meet Your Pelvic FloorChapter 2. Stress Urinary IncontinenceMy Story: Recovery from Stress Urinary IncontinenceStress Urinary Incontinence: No Laughing MatterWhat You Need to Know about Stress Urinary IncontinenceChapter 3. Overactive Bladder and Urge Urinary IncontinenceMy Story: Recovery from Overactive Bladder and Urge Urinary IncontinenceOveractive Bladder and Urge Urinary Incontinence: The Surprising FloodWhat You Need to Know about Overactive Bladder and Urge Urinary IncontinenceChapter 4. Mixed Urinary IncontinenceMy Story: Recovery from Mixed Urinary IncontinenceMixed Urinary Incontinence: The Best and Worst of Both WorldsWhat You Need to Know about Mixed Urinary IncontinenceChapter 5. Pelvic Organ ProlapseMy Story: Recovery from Pelvic Organ ProlapsePelvic Organ Prolapse: The Name Says It AllWhat You Need to Know about Pelvic Organ ProlapseChapter 6. Decreased Sexual SensationMy Story: Recovery from Decreased Sexual SensationDecreased Sexual Sensation: You Can Do Something about ItWhat You Need to Know about Decreased Sexual SensationChapter 7. At-Home Pelvic Floor Muscle Exercise ProgramWhy Pelvic Floor Muscle Exercise Programs Sometimes FailA Pelvic Floor Muscle Exercise Program That WorksPelvic Floor Muscle Exercises Really Are EffectivePelvic Floor Muscle Exercise Program RequirementsHow to Do a Correct Pelvic Floor Muscle ContractionTesting Phase: Test the Strength of Your Pelvic Floor MusclesThe Five F's of a Fit Pelvic FloorFrequently Asked Questions about the Five F's ProgramF#1. Focused and Fast Pelvic Floor Muscle ContractionsF#2. Functional Pelvic Floor Muscle ContractionsF#3. Freedom Pelvic Floor Muscle ContractionsF#4. Fun Pelvic Floor Muscle Contractions (in theBedroom)F#5. Future Pelvic Floor Muscle ContractionsChapter 8. Additional Conservative TreatmentsPelvic Floor Retraining Guided by a Specialist (plusBiofeedback)MedicationBehavior and Diet Modifications Plus Weight ManagementAcupuncturePercutaneous Tibial Nerve StimulationVaginal PessariesUrethral DilationChapter 9. Surgical SolutionsGeneral Principles and Precautions with Transvaginal SurgeryGeneral Considerations for Incontinence SurgeriesTransobturator TapeTension-Free Vaginal TapePubovaginal Sling ProceduresBurch ProcedureMarshall-Marchetti-Krantz ProcedureGeneral Considerations for Pelvic Organ Prolapse SurgeriesCystocele RepairRectocele RepairEnterocele RepairVaginal Vault Repair, or Sacral ColpopexyUterine Suspension ProceduresHysterectomySacral NeuromodulationAdditional ResourcesReferencesIndex

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Book SynopsisProstate cancer is the most common cancer in men in the UK and US and the second most common worldwide. The ABC of Prostate Cancer provides fully illustrated guidance on the treatment and management of prostate cancer. It covers the biology, anatomy, and pathology of prostate cancer, screening, and active surveillance and monitoring.Table of ContentsContributors vii Foreword ix 1 Applied Anatomy of the Prostate 1Prasanna Sooriakumaran Karl-Dietrich Sievert Abhishek Srivastava and Ashutosh Tewari 2 Pathology of Prostate Cancer 5Murali Varma and Ashish Chandra 3 Biology of Prostate Cancer 8R. William G. Watson and John M. Fitzpatrick 4 Prostate Cancer Diagnosis 11Robin Weston Anthony J. Costello and Declan G. Murphy 5 Imaging of Prostate Cancer 14James Halls and Uday Patel 6 Screening for Prostate Cancer 18Richard J. Bryant and Freddie C. Hamdy 7 Active Surveillance 22Judith Dockray Pardeep Kumar Lars Holmberg and Gordon Muir 8 Open Radical Prostatectomy 25Wim van Haute and Hein van Poppel 9 Laparoscopic Radical Prostatectomy 29Pardeep Kumar and Declan Cahill 10 Robotic Radical Prostatectomy 33Ben Challacombe and Jim Peabody 11 Prostate Brachytherapy 37Peter Acher and Rick Popert 12 HIFU 40Louise Dickinson Hashim U. Ahmed and Mark Emberton 13 Cryotherapy for Prostate Cancer 44Alastair Henderson and John Davies 14 Advances in External Beam Radiotherapy 48David Landau Nadia Walsh and Asad Qureshi 15 Recent Advances in Hormonal Therapy 51Heather Payne Reena Davda and Mark R. Feneley 16 Management of Castration-Resistant Prostate Cancer 54Roger S. Kirby Prokar Dasgupta and John M. Fitzpatrick 17 Immunology of Prostate Cancer 57Oussama Elhage Christine Galustian Richard Smith and Prokar Dasgupta 18 New Approaches to Prostate Cancer 63Megan S. Schober Roger S. Kirby and Prokar Dasgupta Index 67

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Book SynopsisA huge number of new technologies have been introduced in recent years to aid in this diagnostic pathway in the form of urine tests, blood tests and imaging modalities. The book focuses on the diagnostic pathways involved, bringing together international leaders in the field who describe the current status of urological investigation.Table of Contents1. Prostate Specific Antigen (PSA).- 2. Prostate Biopsy and Management of a Rising PSA Post Initial Biopsy.- 3. Abnormal Digital Rectal Examination.- 4. Imaging of the Prostate.- 5. Haematuria.- 6. Haematospermia.- 7. Diagnostic Techniques in Male LUTS/BPE.- 8. Storage Lower Urinary Tract Syndromes: Evaluation and Investigations.- 9. Urinary Incontinence.- 10. Recurrent Urinary Tract Infections in Adults.- 11. Loin Pain.- 12. Recurrent Stone Formation.- 13. Testicular Mass and Acute Testicular Pain.- 14. Penile Curvature.- 15. Erectile Dysfunction.- 16. OAT Syndrome.- 17. Male Hypogonadism and Cryptorchidism.- 18. Renal Trauma.- 19. Penoscrotal Trauma.- Enterovesical Fistulae and Pneumaturia.

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Book SynopsisGrab your copy of The 5-Minute Urology Consult, 3e for rapid-fire reference in the clinic. This essential, easy-to-read text was designed to aid in the diagnosis and treatment of urologic problems quickly and efficiently. Engineered for crystal clarity, and chock-full of information and action items, the “5-Minute Consult” series includes facts and recommendations as informed by the most current data available, sourced from actual patient consultations and further reviewed by top academics and physicians.An invaluable resource for urologists, this book is perfect for the busy specialist or practitioner who deals with urologic conditions on a daily basis, as well as residents and fellows prepping for their certification exams.Features:Topics include adult and pediatric urology, and the subspecialties of urologic oncology, endourology, female urology, neurourology, andrology, infectious diseases, and renal transplantatTrade Review'undoubtedly one of the most useful for urologists, regardless of their career level''a considerable amount of practical information in this high-quality work 'European Urology Today – June/July 2015

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Book SynopsisMale urogenital glands (also named male accessory sex glands) have received relatively little attention from electron microscopists, with the possible exception of the prostate gland. Moreover, even though comparative studies have clearly shown that these glands exhibit species-dependent features, very few studies, scattered over various publications, are available on the urogenital glands of man. This volume, the 11th of the series on Electron Microscopy in Biology and Medicine, presents an unprecedented collection of information on the functional microanatomy and cytoarchitecture of these organs in humans. Through the integration of transmission and scanning electron microscopy with a variety of modern techniques, it documents the most important aspects of the histophysiology of these glands from their development to some pathologicalTable of ContentsPreface. 1. Normal and abnormal development of human male accessory sex glands; F. Sinowatz, P. Kellokumpu-Lehtinen, W. Amselgruber. 2. Role of mesenchymal-epithelial interactions in normal and abnormal development of male urogenital glands; G. Cunha. 3. The epithelium of the distal portion of the human spermatic pathway: seminal vesicle, ampulla ductus deferentis, ejaculatory duct; A. Riva, G. Aumüller. 4. Secretion and endocytosis in the seminal vesicles; L. Mata. 5. Functional morphology of prostate gland; G. Aumüller, J. Seitz, A. Riva. 6. Female prostatic glands. A comparative study; L.J.A. Di Dio. 7. Histochemistry and electron microscopy for diagnosis of prostatic cancer; C. Capella, B. Frigerio, G. Finzi, M. Salvadore, A. Bono. 8. A review of the ultrastructure of human prostatic and urethral endocrine-paracrine cells and neuroendocrine differentiation in prostatic carcinoma; K.L. De Mesy Jensen, P.A. Di Sant'agnese. 9. The human bulbourethral and urethral glands; F. Testa-Riva, T. Congiu, A. De Lisa, P.M. Motta. 10. ABH and Lewis antigens in human male accessory sex glands; M. Cossu, M.S. Lantini, R. Migliari. 11. Autonomic innervation of the human male accessory sex glands; A. Vaalasti. Index.

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Book SynopsisThe volume closes with a new comprehensive appendix of preferred instruments.With broad contributions by international authorities in reconstructive urologic surgery, Advanced Male Urethral and Genital Reconstructive Surgery, Second Edition is a valuable resource for all urologists, from residents to reconstructive surgeons.Trade ReviewFrom the reviews of the second edition:“Experts in the field provide comprehensive reviews of important topics in complex urethral and genital reconstructive surgery in this book. … This book is well suited for residents, fellows, and junior attendings who have an interest and experience in urethral and genital reconstruction. … This will be a useful and frequently referenced book in any reconstructive urologist’s library.” (Bradley D. Figler, Doody’s Book Reviews, February, 2014)Table of Contents Ch.1: General Technical Considerations, Instrumentation and Decision Making in Urethroplasty Surgery Steven B. Brandes Ch.2: Male Urethra and External Genitalia Peter A. Humphrey Ch.3: Vascular Anatomy of Genital Skin and the Urethra: Implications for Urethral Reconstruction Steven B. Brandes Ch.4: Lichen Sclerosis Ramón Virasoro, Gerald H. Jordan Ch.5: Imaging of the Male Urethra Nirvikar Dahiya, Christine M. Peterson, Christine O. Menias, Cary L. Siegel Ch.6: Practical Plastic Surgery: Techniques for the Reconstructive Urologist Hema J Thakar, Daniel D Dugi, III Ch.7: The Epidemiology, Clinical Presentation and Economic Burden of Urethral Stricture Keith Rourke Ch.8: Etiology, Histology, and Classification of Urethral Stricture Disease Sean Elliot, Steven B. Brandes Ch.9: Urethrotomy and other Minimally Invasive Interventions for Urethral Stricture Chris F. Heyns Ch.10: Endourethral Prostheses for Urethral Stricture Daniel Yachia, Zeljko Markovic Ch.11: Fossa Navicaris and Meatal Reconstruction Noel A. Armenakas Ch.12: Stricture Excision and Primary Anastomosis for Anterior Urethral Strictures Reynaldo G. Gomez Ch.13: Oral Mucosal Graft Urethroplasty Guido Barbagli, Salvadore Sansalome Ch.14: Lingual Grafts Alchiede Simonato, Andrea Gregori Ch.15: The Augmented Anastomotic Urethroplasty Michael L. Guralnick, R. Corey O'Connor Ch.16: Penile Skin Flaps for Urethral Reconstruction Benjamin N. Breyer, Jack W. McAninch Ch.17: Panurethral Strictures Carlos Guidice Ch.18: The Application of Muscular, Myocutaneous, and Fasciocutaneous Flaps as Adjuncts in Complex Refractory Urethral Disorders Leonard N. Zinman, Jill C. Buckley Ch.19: Posterior Urethral Strictures Steven B. Brandes Ch.20: Staged Urethroplasty Chris McClung, Hunter Wessells Ch.21: Complications of Urethroplasty Ofer Shenfeld Ch.22: Postprostatectomy Strictures Margit Fisch, Daniel Pfalzgraf, C. Phillip Reiss Ch.23: Radiotherapy induced Urethral Strictures: Urethroplasty and Minimally Invasive Methods Steven B. Brandes Ch.24: Complex Urinary Fistulas of the Posterior Urethra and Bladder Steven B. Brandes Ch.25: Reconstruction of Failed Urethroplasty Steve J. Hudak, Allen F. Morey Ch.26: Urethral Stent Complications and Methods for Explantation Jill C. Buckley Ch.27: Reoperative Hypospadias Surgery and Management of Complications Douglas E. Coplen Ch.28: Follow-up Strategies after Urethral Stricture Treatment Chris F. Heyns Ch.29: Urethral Rest as Precursor for Urethroplasty Steve J. Hudak, Allen F. Morey Ch.30: The Use of Patient Reported Outcome Measures in Men with Urethral Stricture Disease Lee C. Zhao, Chris M Gonzalez Ch.31: Reconstruction of Synchrous Urethral Strictures Steve J. Hudak, Allen F. Morey Ch.32: Perineal Urethrostomy Drew Peterson Ch.33: Double Overlapping Buccal Grafts Enzo Palminteri, Elisa Berdondini Ch.34: Reconstruction and Salvage of Failed Male Urethral Slings Jack M Zuckerman, Kurt McCammon Ch.35: Primary and Secondary Reconstruction of the Neophallus Urethra Miroslav L. Djordjevic Ch.36: Artificial Urinary Sphincters: Reoperative Techniques and Management of Complications Landon Trost, Daniel Elliott Ch.37: Pediatric Urethral Strictures Michael H. Johnson, Steven B Brandes and Douglas E. Coplen Ch.38: The Buried Penis in Adults Richard Santucci, Mang Chen Ch.39: Genital Skin Loss and Scrotal Reconstruction Dan Rosenstein Ch.40: Surgery for Priapism Arthur Burnett, Ifeanyichuku Anusionwu Ch.41: Penile Skin Grafting and Resurfacing of the Glans Giulio Garaffa, Salvatore Sansalone, David John Ralph Ch.42: Peyronie's Disease Reconstruction: Simple and Complex Laurence A Levine, Stephen M. Larsen Ch.43: New Advances in Penile Implant Surgery Steven K Wilson, John D Terrell Ch.44: Penile Fracture Jack Mydlo, Leo Doumanian Ch.45: Muscle, Nerve and Vascular Sparing Techniques in Anterior Urethroplasty Sanjay B. Kulkarni, Pankaj M Joshi Ch.46: Tissue Engineering of the Urethra: The Basics, Current Concept, and the Future Ryan P. Terlecki, Anthony Atala Ch.47: Non-transecting bulbar urethroplasty A R Mundy, Daniela E. Andrich Ch.48: Vascular Surgery For Erectile Dysfunction Jacqueline D. Villalta, Tom F. Lue Ch.49: Penile and Inguinal Reconstruction and Tissue Preservation for Penile Cancer Steven B. Brandes, Jairam R Eswara Ch.50: Post Prostatectomy Incontinence (evaluation and practical urodynamics) H. Henry Lai, Timothy B Boone

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Book SynopsisThe sixth edition of The Kelalis-King-Belman Textbook of Clinical Pediatric Urology presents state-of-the-art knowledge and common-sense practice in all areas of clinical pediatric urology in a single, easily accessible volume. Clinical in orientation and practical in presentation, it covers every disorder and disease, diagnostic method, and appropriate treatment in pediatric urology from the embryo onwards. Widely acknowledged as the leading reference in the field, the book is essential reading for all practitioners who deal with urological disorders of childhood, whether trainees, residents or experienced specialists. The book begins with chapters on evaluating the patient and general principles of pediatric urology, including the use of advanced diagnostic imaging techniques and the increasing importance of minimally invasive surgical techniques. It then proceeds through the entire urinary tract from adrenal gland to external genitalia, discussing anatomy, normal Trade ReviewPraise for the previous edition:"I suspect this is the bible for paediatric urologists... it should be available in every urology department"—Urology News"Lots of good illustrations, clinical images and radiology. It has some very strong chapters on reconstructive surgery and duplex anomalies, and some interesting chapters on office ultrasonography and upper tract urodynamics. …I think that this book will be a worthy addition to most departmental libraries."—Journal of Pediatric Urology"This is a standard textbook. Paediatric urologists will want their own copies. Departments of paediatric surgery and nephrology need a departmental copy, and hospital libraries can easily justify the outlay of a book, if their institution looks after children."—Pediatrics and Child Health"Exhaustive and authoritative... This is the definitive text, well written by authorities in the field. Anyone with a primary or peripheral interest in pediatric urology should buy it and study it." —Journal of Urology"This book should have a place in the library of every pediatric urologist and other urologists who care for children. It also should be an essential resource for urologists and pediatric urologists in training. The latest edition is comprehensive, well written, and deftly illustrated. The expert contributors provide the most up-to-date advances, treatments, and opinions in the field." -Harry Koo, MD (Hackensack University Medical Center)Praise for the previous edition:"I suspect this is the bible for paediatric urologists... it should be available in every urology department"—Urology News"Lots of good illustrations, clinical images and radiology. It has some very strong chapters on reconstructive surgery and duplex anomalies, and some interesting chapters on office ultrasonography and upper tract urodynamics. …I think that this book will be a worthy addition to most departmental libraries."—Journal of Pediatric Urology"This is a standard textbook. Paediatric urologists will want their own copies. Departments of paediatric surgery and nephrology need a departmental copy, and hospital libraries can easily justify the outlay of a book, if their institution looks after children."—Pediatrics and Child Health"Exhaustive and authoritative... This is the definitive text, well written by authorities in the field. Anyone with a primary or peripheral interest in pediatric urology should buy it and study it." —Journal of UrologyTable of ContentsEvaluation of the Pediatric Urologic Patient. History & Physical Examination of the Child. Laboratory Assessment of the Pediatric Urologic Patient. Fetal Urology and Prenatal Diagnosis. In-Office Ultrasonography. Pediatric Renal Nuclear Medicine. Prenatal and Postnatal Urologic Emergencies. Urinary Tract Infections in Children. Fungal, Parasitic and Other Inflammatory Disease of the Genitourinary Tract. Anesthesia and Pain Management for the Pediatric Urology Patient. Office Pediatric Urology. Principles of Minimally Invasive Surgery. Pediatric Fluid Management. Problems with Transitional Care. Embryology of the Genitourinary Tract. The Adrenal. Adrenal or Suprarenal Gland Development. Radiologic Assessment of the Adrenal. Adrenal Tumors and Functional Consequences. Surgery of the Adrenal in Pediatric Patients. The Kidney. Basic Science of the Kidney. Renal Vasculature and Kidney. Renal Anomalies. Fetal and Neonatal Renal Function. Cystic Kidney Disease. Acute Kidney Injury. Renal Transplantation. Renal Calculus Disease. Endourology for Stone Disease. Renal Parenchymal Imaging in Children. Assessment of Renal Obstructive Disorders: Ultrasound, Nuclear Medicine, and Magnetic Resonance Imaging. Ureteropelvic Junction Obstruction and Multicystic Dysplastic Kidney: Surgical Management. Laparoscopic Nephrectomy and Pyeloplasty. Wilm's Tumor. Surgical Approaches for Pediatric and Adolescent Renal Tumors. Upper Urinary Tract Trauma. The Ureter. The Ureter. Ureteral Development. The Imaging of Reflux and Ureteral Disease. Ureteral Anomalies and their Surgical Management. Megaureter. Ureteral Duplication Anomalies: Ectopic Ureters and Ureteroceles. Laparoscopic Management of Duplication Anomalies. Vesicoureteral Reflux: Etiology - Anatomical and Functional. Non-Surgical Management of Vesicoureteral Reflux. Surgery for Vesicoureteral Reflux. Minimally Invasive Approaches to Correct Primary Vesicoureteral Reflux. Injection Therapy for Vesicoureteral Reflux. The Bladder and Prostate. Basic Science of Prostatic Development. Basic Science of the Urinary Bladder. Embryology of the Anterior Abdominal Wall, Bladder, and Proximal Urethra. Radiologic Assessment of Bladder Disorders. Urodynamic of the Lower and Upper Urinary Tract. Neurologic Control of Storage and Voiding. Neurogenic Voiding Dysfunction and Functional Voiding Disorders: Evaluation and Non-Surgical Management . Non Neurogenic Daytime Incontinence and Nocturnal Enuresis. Constipation and Lower Urinary Tract Symptoms. Operations for the Weak Bladder Outlet. Bladder Augmentation: Current and Future Techniques. Urinary diversion. The Malone Antegrade Continence Enema (MACE). Minimally Invasive Approaches to Lower Urinary Tract Reconstruction. Genitourinary Rhabdomyosarcoma and Other Bladder Tumours. Exstrophy and Epispadias. Unusual Conditions of the Bladder: Including Bladder Trauma, Urachal Anomalies, and Bladder Diverticula. Posterior Urethral Values. Prune Belly Syndrome. Surgical Excision of Urachal Anomalies. Urethra, External Genitalia and Retroperitoneum. Basic Science of the Genitalia. Basic Science of the Testis. Gonads, Genital Ducts and Genitalia. Disorders of Sexual Differentiation. Anorectal Malformation and Cloaca . Surgery for Intersex Disorders and Urogenital Sinus. Hypospadias. Pediatric Urethral Trauma and Stricture. Abnormalities of the Penis and Scrotum. Penile Replacement Surgery. Hernia, Hydroceles, Testicular Torsion and Varicocele. Minimally Invasive Management of Inguinal Hernias. Surgical Management of the Undescended Testis. Cryptorchidism. Testicular and Paratesticular Tumors in Children. Tumors of the Retroperitoneum. Tissue Engineering for Pediatric Urology. Study Designs and Hierarchy of Evidence.

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Book SynopsisSenior investigators internationally have here collaborated to produce an international reference work. Each contributor provides critical and thought provoking concepts and ideas based on the latest developments in their field. The result is a must read and timely reference work for investigators who are interested in how spermatogenesis is currently understood and which are the most promising avenues for future research; an Introduction sets the context for the chapter and points out the relevance of the research for basic research scientists and clinicians.Trade Review"This is a remarkable addition to the field of spermatogenesis, furthering ourunderstanding of meiosis and new developments in the conversion of earlyspermatocytes to haploid spermatids, a process clinically relevant to thetreatment of nonobstructive azoospermia. It uniquely addresses the contemporarychallenges of environmental spermatotoxins."Irvin H Hirsch, MD (Thomas Jefferson University)Table of ContentsPreface Contributors 1. Golgi apparatus regulation of differentiation: A case study for male germ cells of the rat testis Louis Hermo, Regiana L. Oliveira, Charles E. Smith, Catherine E. Au, and John J. M. Bergeron2. Androgen regulation of spermatogenesis William H. Walker3. Testicular immunoregulation: The role of Tyro3, Axl, and Mer receptor tyrosine kinases and pattern recognition receptors Fei Wang, Qian Jiang, and Daishu Han4. Inflammation and Spermatogenesis Maria Susana Theas, Patricia Verónica Jacobo, Cecilia Valeria Pérez, Vanesa Anabella Guazzone, and Livia Lustig5. Junctional adhesion molecule (JAM) family: Recent findings and their role and regulation in spermatogenesis Kun Huang and Wing-Yee Lui6. Sertoli cell immune regulation within the testis Gurvinder Kaur, Kandis Wright, Robin Hannah Greer, Karl Mueller, Allan Haynes, and Jannette M. Dufour7. The mitotic phase of spermatogenesis: Recent advances and perspectives Kin Lam Fok and Hsiao Chang Chan8. Genetics of mammalian meiosis Fang Yang and P. Jeremy Wang9. Roles of membrane and nuclear estrogen receptors in spermatogenesis Paul S. Cooke, Manjunatha K. Nanjappa, Sergei G. Tevosian, and Rex A. Hess10. Regulation of fertility and infertility in humans Nahid Punjani, Ryan Flannigan, and Peter N. Schlegel11. Male infertility: Evaluation and treatment Ryan Flannigan and Marc Goldstein12. Effects of chemical pollutants on spermatogenesis and implications in male infertility Chris KC Wong13. Advances in our understanding of human spermatogenesis Qing Wen, Elizabeth I. Tang, Tito Jesus, Bruno Silvestrini, and C. Yan Cheng14. A look into the testis as a reservoir for HIV and ZIKV—A reproductive biologist’s perspective Elizabeth I. Tang, Christopher L. Robinson, Chi Nok Chong, Shuibing Chen, and C. Yan Cheng15. Cytoskeletons (F-actin) and spermatogenesis Liza O’Donnell and Peter G. Stanton16. Roles of mTOR signaling in spermatogenesis Lan Ye and Ke Zheng17. Does planar cell polarity matter during spermatogenesis? Linxi Li, Haiqi Chen, Qingquan Lian, Ren-Shan Ge, and C. Yan Cheng18. Computational characterization and integrative analysis of proteins involved in Spermatogenesis Pranitha Jenardhanan, Manivel Panneerselvam, and Premendu P. Mathur19. Effects of chemical exposures on testis cell-cell interactions and endocrine function Rachel C. Knight, Jennifer R. Panizzi, and Benson T. Akingbemi20. Environmental toxicants on Leydig cell function Leping Ye, Xiaoheng Li, Xiaomin Chen, Qingquan Lian, and Ren-Shan GeIndex

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Book SynopsisPreterm birth (PTB) is defined as delivery before 37 weeks of gestation. Chapter One focuses on important aspects regarding potential risk factors, potential complications, and clinical analyses of PTB. Chapter Two summarizes the basic confounders that may indeed affect prolongation interval based on findings of both prospective and large retrospective series of tertiary centres. Chapter Three offers new approaches to diminish the deleterious impacts of preterm birth, such as neonatal death and the development of cerebral palsy. Chapter Four discusses the burden of late foetal mortality (LFM) in perinatal assistance.

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Book SynopsisThis book is intended for urologists and pathologists who practice in an office setting. In this setting, bladder and prostate diseases are most commonly encountered. Therefore, bladder and prostate biopsy and urine cytology specimens are frequently obtained by urologists, which require pathologists assistance to interpret. In the office setting, communication between urologists and pathologists becomes feasible, which is paramount for accurate diagnosis and better patient management. For this purpose, this book includes clinically relevant information for pathologists, concise pathology terminology, and diagnostic tests for urologists. This book describes the common clinical and pathological entities, and is written in a bullet format for easy and quick reference. For visual review, over 150 diagrams, histologic images, and other images are included. The first and second chapters describe bladder and prostate diseases, focusing on clinical-pathological correlation. Therefore, this book is also useful for pathology and urology residents in training, in preparation for board examination(s), or as a refresher reference for recertification. The third chapter is dedicated to office-based pathology laboratory services, which outlines laboratory instrumentation, procedures, and regulatory requirements. This information is useful for urologists and pathologists who are involved in the management of an office-based pathology laboratory. Finally, I greatly appreciate Josephine Wu DDS, Esq. and Miao Cui MD, MS, who contributed to this excellent third chapter.

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Book SynopsisManual Therapy for the Prostate presents a comprehensive guide to the prostate that includes manual treatment procedures designed to resolve common prostate issues. Based on author Jean-Pierre Barral’s clinical practice and his innovative theory of visceral manipulation, the book provides a structured framework rooted in anatomy and physiology. By precisely applying manual techniques to the prostate and surrounding structures, practitioners can successfully treat prostate problems and help patients avoid surgical procedures or medication.Featuring detailed, full-color anatomy illustrations throughout, the book begins with a discussion of the anatomical structure and function of the prostate. Causes of prostate dysfunction are revealed, including predisposing factors such as age, ethnicity, stress level, diet, and tobacco and alcohol usage. The book explores the signs, symptoms, prevention, and allopathic treatments for disease and dysfunction of the prostate. Examination and manual treatment protocols, contraindications and precautions, and the various goals the practitioner is working to achieve are clearly described. Explaining how all pelvic structures have links with the rest of the body, the book concludes by demonstrating how the entire body is interconnected and elucidating the influence of stress and emotional issues in prostate dysfunction.

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Book SynopsisIn The Garden of Fertility, certified fertility educator Katie Singer explains how easy it is to chart your fertility signals to determine when you are fertile and when you are not. Her Fertility Awareness method can be used to safely and effectively prevent or help achieve pregnancy, as well as monitor gynecological health. Singer offers practical information, illuminated with insightful personal stories, for every woman who wants to learn to live in concert with her body and to take care of her reproductive health naturally.The Garden of Fertility provides: Directions (and blank charts) for charting your fertility signals Instructions for preventing pregnancy naturally – a method virtually as effective as the Pill, with none of its side effects. Guidelines for timing intercourse to enhance your chances of conceiving without drugs or hormones Information to help you use your charts to gauge your reproductive health – to determine whether you’re ovulating; if you have a thyroid problem, low progesterone levels, or a propensity for PCOS or miscarriage; or if you’re pregnant Nutritional and nonmedical strategies for strengthening your gynecological health Clear descriptions of reproductive anatomy, hormonal changes throughout the menstrual cycle, and how conception occurs

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Book SynopsisBladder cancer is the fourth most common type of cancer in men and the eighth most common in women. This book includes within its scope the prevention, risk factors, symptoms, diagnosis, treatment, and rehabilitation of bladder cancer. Leading-edge scientific research from throughout the world is presented.

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Book SynopsisProstate cancer is the most common type of cancer in men (other than skin cancer). Of all the men who are diagnosed with cancer each year, more than one-fourth have prostate cancer. This book includes within its scope the prevention, risk factors, symptoms, diagnosis, treatment, and rehabilitation of prostate cancer. Leading-edge scientific research from throughout the world is presented.

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Book SynopsisTestosterone is a steroid hormone from the androgen group. Testosterone is primarily secreted in the testes of males and the ovaries of females although small amounts are secreted by the adrenal glands. It is the principal male sex hormone and an anabolic steroid. In both males and females, it plays key roles in health and well-being. Examples include enhanced libido, energy, immune function, and protection against osteoporosis. On average, the adult male body produces about twenty times the amount of testosterone that an adult female''s body does. This book presents new and important research in this field from around the world.

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Book SynopsisThe world-wide prevalence of sexually transmitted infections (STIs) is a cause of concern for the public and health organisations. Young age of sexual debut, breakdown of relationships, travel, mobility, relationship explorations, social instability, between other socio-economic factors, contribute to the loss monogamous sexual relationships. The resultant multiplicity of sexual relationships predispose to STIs. The Sexually Transmitted Infections book provides an overall practical account for the benefit of generalists and Primary Care physicians, who would encounter the patients'' problems first. The emphasis on clinical issues, drawing from the author''s 30 years of progressive clinical experience in Primary Care, Urology, Obstetrics and Gynaecology and Venereology, share expertise with those intending to specialise. Patients who wish to acquire unbiased in depth knowledge about sexually transmitted infections, will find answers to their questions. Many of these questions were asked times and times again by patients who shared similar concerns and anxieties. The book covers a wide range of clinical practices and facilities and addresses areas of low resource settings, which will make the account relevant to developing primary health units.

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Book SynopsisThe reproductive system and all of its functions related to sex, conception, pregnancy and delivery, all actions aimed at keeping it functioning optimally and free from diseases and harmful traditional practices are explored in this book.

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Book SynopsisThis book seeks to provide a general medical audience with a picture of the current state of play with regards to the evaluation and treatment of patients with erectile dysfunction. The authors aim to cover everything from the primary care approach to addressing the issue, through the important psychological causes and consequences of erectile dysfunction, the new diagnostic techniques involved in assessing the problem, the complex interplay between vascular and neurological disorders, as well as problems relating to hormonal disruption and diabetes.

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Book SynopsisMonopolar transurethral resection still represents the standard endoscopic treatment approach in benign prostatic enlargement related to lower urinary tract obstruction. The method gained acknowledgement as a first choice therapeutic modality in medium size benign prostatic hyperplasia (BPH) treatment and the majority of clinical research regarded it as such. Endoscopic vaporization was introduced while trying to maintain therapeutic efficacy while reducing the peri- and post-operative morbidity, and it was easily adopted, as it required no special equipment or surgical skills. This book examines endoscopic vaporization in lower urinary tract pathology, from monopolar to plasma. The present publication follows the interest this treatment has gathered as well as the inevitable downfall when facing the test of time as well as the less flattering comparison to other methods.

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Book SynopsisThis book with its most comprehensive and illuminating chapters covers all the relevant areas of hemodialysis practice including access for hemodialysis, hemodialysis modeling and membranes, timing of hemodialysis, infections in hemodialysis, the application of hemodialysis in extra-renal disease, the various formats of hemodialysis from nocturnal through SLED to apheresis and the wearable artificial kidney, convective hemodialysis methodologies, and various clinical aspects of hemodialysis including protein-calorie-malnutrition, inflammation, haemoglobin stability and sleep disorders in ESRD patients and so on. Furthermore, the inclusion of such new topics as the syndrome of rapid-onset end stage renal disease (SORO-ESRD), and the place of reduced HBV testing among ESRD patients in regions with less de novo HBV incidence to cut down on costs of delivery of hemodialysis care without loss of quality of care, are new paradigms that would play stronger roles in hemodialysis care, well into the 21st century.

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Book SynopsisThis book presents review articles in the study of genitourinary medicine. Topics include basic research that investigates the epigenetic mechanisms in urogenital cancers; the role of matrix metalloproteinases in urothelial cancers; the role of toll-like receptor genes in prostate cancers; recent emerging and novel treatment modalities in advanced metastatic renal cell and bladder carcinomas; novel mouse models for studying malformations in the genitourinary tract; the role of tissue engineering in genitourinary regenerative medicine; and clinical management of patients with Vesicoureteric reflux. Apart from the very well-known Wilms tumour (a form of paediatric hereditary kidney tumours), little is known about paediatric nephritic syndrome and their genetic causes and clinical manifestations. Hence, a special chapter has been included that describes the recent genetic technologies that identify gene mutations in patients with paediatric nephritic syndrome. The specific gene mutations found in these patients are often associated with rapid renal failures, disease progression and poor survival outcome. Each of the articles presented by authors from all over the world are renowned and experts in their own field of research. The authors are based either in research and/or a clinical setting and the articles are only a summary of the view points of each of these authors.

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Book SynopsisIn the last few years, there has been a significant volume of research published in the field of urinary dysfunction. Urinary incontinence can affect both men and women of all age-groups with varying degrees of severity. It is becoming an increasingly dominant health care issue with enormous economic burden and places considerable impact on the overall quality of life, impairing several areas with physical, social, emotional and sexual limitations. This up-to-date and exhaustively written textbook addresses a very difficult, underestimated, and probably inadequately considered clinical subject. This book provides comprehensive information on urinary incontinence and is primarily intended for medical practitioners, residents and medical students for daily practice. However the general public will find this book easy to read and provides ample information that is useful in understanding urinary incontinence.

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Book SynopsisLearn the fundamental principles and clinical applications of the diagnostic and risk assessment imaging test of choice for prostate cancer: prostate MRI Although prostate cancer is the second leading cause of cancer death in men in the USA, it can be treated successfully if detected early. Disease management has gradually changed to a paradigm that relies on close monitoring through active surveillance in select patients, as well as ongoing refinements in treatment interventions, including minimally invasive procedures. This has resulted in a critical need for a more exacting methodology for performing targeted biopsies, assessing risk levels, and devising treatment strategies. Prostate MRI has emerged as the most precise, state-of-the-art imaging modality for prostate cancer diagnosis and management, thereby creating an immediate demand for radiologists to become proficient in its use. Conceived and edited by a leading authority, with contributions from renowned experts in the field, MRI of the Prostate: A Practical Approach is the first book to tackle this important topic. It provides an overview of the fundamentals of prostate MRI acquisition, interpretation, and reporting. Readers will benefit from a wide range of insightful perspectives gleaned from years of hands-on experience. Key Highlights Prostate Imaging Reporting and Data System (PI-RADS) for prostate MRI interpretation and cancer risk scoring Clinical pearls on the optimization and application of prostate MRI for risk assessment, disease staging, MRI-targeted biopsy, recurrent disease, and active surveillance The emerging utilization of PET and PET/MRI for primary prostate cancer evaluation More than 700 illustrations with one entirely image-based chapter featuring educational case studies Radiologists will learn how to optimally perform and interpret prostate MRI, and referring physicians will learn to integrate it into day-to-day practice. This book is an essential resource for radiologists and radiology residents, as well as urologists, oncologists, MRI technicians, and other medical practitioners who treat patients with genitourinary disorders.Table of Contents1 Introduction to Prostate Cancer: Clinical Considerations 2 Prostate Cancer Pathology 3 Introduction to Prostate MRI Protocols: Hardware, T2-Weighted Imaging and MR Spectroscopy 4 Diffusion-Weighted Imaging of the Prostate 5 Dynamic Contrast-Enhanced MRI of the Prostate 6 Prostate Imaging–Reporting and Data System (PI-RADS) 7 Prostate Cancer Staging and Surgical Planning 8 Post-Treatment Follow-Up and Assessment for Recurrence 9 Prebiopsy MRI and MRI-Targeted Biopsy 10 MRI and Active Surveillance 11 PET/CT and PET/MR Imaging Evaluation of Prostate Cancer 12 Teaching Atlas of Instructional and Interesting Cases

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Book SynopsisAlbuminuria may not only serve as an early marker of advanced disease, but may also serve as a predictor of disease progression and poor outcome. This fact makes this book very crucial and timely. The book is composed of ten chapters written by experts from seven different countries. It is well classified to serve its purpose, divided in three broad sections. The first section deals with the clinical evaluation and implications of albuminuria. It also covers the molecular, cellular and biochemical basis of albuminuria. The second section is geared towards albuminuria noted in special clinical conditions; diabetic nephropathy, cardiovascular diseases, resistant hypertension and following renal transplantation and exercise. The third and final section covers albuminuria among the extremes of age; both the paediatric and the fastest growing elderly group.

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Book SynopsisThis book is a cumulative work that covers ureteral anatomy, physiology, and disorders. It aims to highlight the ureters by bringing together national and international experts in their respective fields to discuss ureteral pathology and management of ureteral disease. Chapters discussing ureteral trauma, injury, obstruction, stones, cancers, surgeries, and tissue engineering will enhance patient care and introduce us to the future of ureteral surgery. At the very least, this book will improve overall medical knowledge on these often ignored but vital urinary structures.

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Book SynopsisThis book contains all you need to know about the prostate from its anatomy to the most recent sophisticated robotic technical procedures. This book provides a comprehensive understandable account of benign and malignant prostate conditions, and is designed to be undemanding yet thorough and informative. Medical students will find this book useful because of its concise, easy-to-follow format, in addition to its depth and breadth of knowledge. Interns and residents, as well as practising physicians and family doctors will consider it an efficient and current reference. Each chapter is self contained to make it easier to obtain information about a particular topic without having to refer to the whole book. The book is superbly illustrated throughout in order to enhance the clarity and understanding of the contents. Over 1500 references are cited for those who wish to have a more in-depth insight. The text and references are up to-date and include the most recent innovations, ensuring that the manuscript will remain relevant for some years to come. More than 30 qualified medical practitioners have contributed to the authorship about aspects with which they are clinically involved on a regular daily basis. Some are renowned experts in their field. The book contains 15 chapters. Six chapters are devoted to the benign prostate and provide practical advice regarding diagnosis and treatment. The remaining nine chapters are devoted to the detection, diagnosis, prognosis, treatment and outcomes of prostatic cancer, which is the most common tumour found in men.

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Book SynopsisUrinary tract infections (UTI) are one of the most common bacterial infections seen. Episodes of UTI can effectively be treated with antibiotics, often given on an empirical basis. In this book, the authors present current research in UTI''s. Topics discussed in this compilation include the antibiotic and non-antibiotic methods of prophylaxis for recurrent UTI''s; UTI''s in children; virulence factors of uropathogenic Escherichia coli and their role in development of UTI''s; and the treatment for UTI''s due to multidrug-resistant bacteria.

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