Urology and urogenital medicine Books

Book SynopsisTrade ReviewDoody's Core Titles® 2022 "This surgical atlas will continue to serve as the go-to resource for urologists preparing for minimally invasive urologic surgical procedures." ©Doody's Review Service, 2022, Mihir S Shah, MD (Thomas Jefferson University) Doody's Score: 4 Stars!Table of Contents1.Patient Preparation and Positioning for Laparoscopic and Robotic Urologic Surgery 2.Laparoscopic/Robotic Camera and Lens Systems 3.Basic Instrumentation 4.Stapling and Reconstruction 5.The da Vinci Surgical System 6.Considerations for the Assistant 7.Anesthetic Considerations for Laparoscopic and Robotic-Assisted Surgery 8.Insufflators and the Pneumoperitoneum 9.Ports and Establishing Access into the Peritoneal Cavity 10.Retroperitoneal Access 11.Exiting the Abdomen and Closure Techniques 12.Complications of Laparoscopic and Robotic-Assisted Surgery 13.Laparoscopic and Robotic-Assisted Laparoscopic Pelvic Lymph Node Dissection 14.Laparoscopic and Robotic-Assisted Retroperitoneal Lymph Node Dissection 15.Endoscopic Subcutaneous Modified Inguinal Lymph Node Dissection for Squamous Cell Carcinoma of the Penis 16.Laparoscopic Simple Nephrectomy 17.Laparoscopic Radical Nephrectomy 18.Nephroureterectomy 19.Laparoscopic Partial Nephrectomy 20.Laparoscopic Live Donor Nephrectomy 21.Laparoscopic Renal Cyst Decortication 22.Laparoscopic Renal Biopsy 23.Laparoscopic and Percutaneous Delivery of Renal Ablative Technology 24.Minimally Invasive Renal Recipient Surgery 25.Laparoscopic Pyeloplasty 26.Ureterolysis 27.Laparoscopic and Robotic-Assisted Ureteral Reimplantation 28.Laparoscopic/Robotic Boari Flap Ureteral Reimplantation 29.Laparoscopic Appendiceal Onlay Flap and Bowel Reconfiguration for Complex Ureteral Stricture Reconstruction 30.Buccal Mucosa Graft for Ureteral Strictures 31.Pyelolithotomy and Ureterolithotomy 32.Robotic-Assisted and Laparoscopic Simple Prostatectomy 33.Transperitoneal Radical Prostatectomy 34.Preperitoneal Robotic-Assisted Radical Prostatectomy 35.Robotic-Assisted Radical Cystectomy 36.Robotic-Assisted Intracorporeal Ileal Conduit 37.Continent Urinary Diversion 38.Robotic-Assisted Laparoscopic Partial Cystectomy 39.NOTES-Assisted Laparoscopic Transvesical Bladder Diverticulectomy 40.Laparoscopic Adrenalectomy 41.Partial Adrenalectomy 42.Laparoscopic Orchiopexy 43.Laparoscopic Orchiectomy 44.Laparoscopic Varicocelectomy 45.Laparoscopic Denervation for Chronic Testicular Pain

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Book SynopsisThis book acquaints the clinicians with the most frequent problems that may occur after kidney transplantation. It deals with the most worrying extra-renal complications that may affect the kidney transplant recipient, namely infection, cardiovascular disease and malignancy.Table of Contents1. Man's Universe of Symbols 2. Human Values in a Changing World 3. Comments on Aggression 4. Systems Perspectives on the Problem of Mental Illness 5. A Definition of the Symbol 6. An Etymology of Symbolism 7. The Evolutionary Origins of Symbolism 8. The Mind-Body Problem: A New View 9. General Theory of Systems: Application to Psychology 10. Toward a Generalized Theoretical Model for Psychology 11. Problems of Education in America 12. On Interdisciplinary Study

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a huge range and FREE tracked UK delivery on ALL orders.

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a huge range and FREE tracked UK delivery on ALL orders.

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Book SynopsisSenior investigators internationally have here collaborated to produce an international reference work. Each contributor provides critical and thought provoking concepts and ideas based on the latest developments in their field. The result is a must read and timely reference work for investigators who are interested in how spermatogenesis is currently understood and which are the most promising avenues for future research; an Introduction sets the context for the chapter and points out the relevance of the research for basic research scientists and clinicians.Trade Review"This is a remarkable addition to the field of spermatogenesis, furthering ourunderstanding of meiosis and new developments in the conversion of earlyspermatocytes to haploid spermatids, a process clinically relevant to thetreatment of nonobstructive azoospermia. It uniquely addresses the contemporarychallenges of environmental spermatotoxins."Irvin H Hirsch, MD (Thomas Jefferson University)Table of ContentsPreface Contributors 1. Golgi apparatus regulation of differentiation: A case study for male germ cells of the rat testis Louis Hermo, Regiana L. Oliveira, Charles E. Smith, Catherine E. Au, and John J. M. Bergeron2. Androgen regulation of spermatogenesis William H. Walker3. Testicular immunoregulation: The role of Tyro3, Axl, and Mer receptor tyrosine kinases and pattern recognition receptors Fei Wang, Qian Jiang, and Daishu Han4. Inflammation and Spermatogenesis Maria Susana Theas, Patricia Verónica Jacobo, Cecilia Valeria Pérez, Vanesa Anabella Guazzone, and Livia Lustig5. Junctional adhesion molecule (JAM) family: Recent findings and their role and regulation in spermatogenesis Kun Huang and Wing-Yee Lui6. Sertoli cell immune regulation within the testis Gurvinder Kaur, Kandis Wright, Robin Hannah Greer, Karl Mueller, Allan Haynes, and Jannette M. Dufour7. The mitotic phase of spermatogenesis: Recent advances and perspectives Kin Lam Fok and Hsiao Chang Chan8. Genetics of mammalian meiosis Fang Yang and P. Jeremy Wang9. Roles of membrane and nuclear estrogen receptors in spermatogenesis Paul S. Cooke, Manjunatha K. Nanjappa, Sergei G. Tevosian, and Rex A. Hess10. Regulation of fertility and infertility in humans Nahid Punjani, Ryan Flannigan, and Peter N. Schlegel11. Male infertility: Evaluation and treatment Ryan Flannigan and Marc Goldstein12. Effects of chemical pollutants on spermatogenesis and implications in male infertility Chris KC Wong13. Advances in our understanding of human spermatogenesis Qing Wen, Elizabeth I. Tang, Tito Jesus, Bruno Silvestrini, and C. Yan Cheng14. A look into the testis as a reservoir for HIV and ZIKV—A reproductive biologist’s perspective Elizabeth I. Tang, Christopher L. Robinson, Chi Nok Chong, Shuibing Chen, and C. Yan Cheng15. Cytoskeletons (F-actin) and spermatogenesis Liza O’Donnell and Peter G. Stanton16. Roles of mTOR signaling in spermatogenesis Lan Ye and Ke Zheng17. Does planar cell polarity matter during spermatogenesis? Linxi Li, Haiqi Chen, Qingquan Lian, Ren-Shan Ge, and C. Yan Cheng18. Computational characterization and integrative analysis of proteins involved in Spermatogenesis Pranitha Jenardhanan, Manivel Panneerselvam, and Premendu P. Mathur19. Effects of chemical exposures on testis cell-cell interactions and endocrine function Rachel C. Knight, Jennifer R. Panizzi, and Benson T. Akingbemi20. Environmental toxicants on Leydig cell function Leping Ye, Xiaoheng Li, Xiaomin Chen, Qingquan Lian, and Ren-Shan GeIndex

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Book SynopsisErectile dysfunction (ED) affects 20-30 million American men, most of whom are over 50 years of age. In a UK-based study, 32% of British men had difficulty obtaining an erection, 20% with maintaining an erection. In recent years the physiology and pathophysiology of ED have changed our understanding of what ED is from a purely psychological-based disorder to a multifactorial one, with neurological, endocrinological, psychological factors and the role of the vascular system. Recently identified risk factors include diabetes, cardiovascular disease, spinal cord injury, smoking, depression, atherosclerosis, hypertension, pelvic surgery and trauma, pharmacological medications, arthritis, peripheral vascular disease, substance abuse, endocrine abnormalities and peptic ulcer disease. Many ED patients have a combination of these risk factors, thus exacerbating ED further. The treatment of ED was revolutionized in 1998 with the introduction of sildenafil. Beside these oral treatments, newer injectable agents are being investigated as are topical preparations. However, not all patients are tolerant of oral agents, many patients still require penile reconstruction with penile implants, an option with low complications and morbidity. There are options for all patients and this excellent, updated text, edited by some of the world's leading authorities - Culley Carson, Roger Kirby and Irwin Goldstein - discusses them all.Trade Review'This textbook provides a comprehensive review of the major aspects of erectile dysfunction, with contributions from the acknowledged experts in this field ... The volume, which is presented in a clear, concise and extremely readable fashion, will be of particular interest to surgeons, physicians and health care workers interested in erectile dysfunction.' (British Journal of Surgery)Table of ContentsSection I Basic Science 1. History of Erectile Dysfunction 2. The history of the International Society for Sexual Medicine 3. Epidemiology of Erectile Dysfunction 4. Anatomy of Erectile Function 5. Microscopic Anatomy of Erectile Tissue 6. Vascular Physiology of Erectile Function 7. Central Nervous System Control of Sexual Function in the Male and Female 8. Ejaculatory Physiology 9. Endocrinology of Male Sexual Function 10. Pathophysiology of Erectile Dysfunction: Molecular Basis 11. Neurotransmitters in the Corpus Cavernosum: Nitric Oxide and Beyond 12. Receptor Pharmacology Related to Erectile Dysfunction 13. Environmental Erectile Dysfunction 14. Erectile Dysfunction and Treatment of Carcinoma of the Prostate Section II Risk Factors and Clinical Evaluation 15. Vascular Risk Factors for Erectile Dysfunction 16. Mediterranean Diet and Erectile Dysfunction 17. Pharmacologic Risk Factors for Altered Male Sexual Function 18. Male Sexual Dysfunction and the Prostate 19. Basic Clinical Assessment of the Patient with Erectile Dysfunction 20. The Contemporary Role of Penile Duplex Scanning 21. Imaging in Erectile Dysfunction 22. Neurophysiologic Testing in Erectile Dysfunction 23. Biopsy of the Corpus Cavernosum 24. Endocrine Evaluation of Male Sexual Dysfunction 25. The Biopsychosocial Evaluation of Erectile Dysfunction 26. Erectile Dysfunction: the Couple Context 27. Primary Care Evaluation and Treatment of Erectile Dysfunction Section III Treatment of Sexual Dysfunction 28. PDE5 Inhibitors: Molecular Basis 29. PDE5 Inhibitors: Non ED Vascular Effects 30. Sildenafil: Pharmacologic and Clinical Treatment of Erectile Dysfunction 31. Tadalafil: Long Acting PDE5 Inhibitor 32. Vardenafil: Biochemically Potent PDE5 Inhibitor 33. The Princeton Guidelines for Treatment 34. PDE5: Safety and Adverse Events 35. Diagnosis and Treatment of Hypogonadism 36. Central Nervous System Agents for the Treatment of Erectile Dysfunction 37. Intracavernosal Therapy for Erectile Dysfunction 38. Invicorp in Erectile Dysfunction 39. Vacuum Systems for Erectile Dysfunction 40. Integrated Sex Therapy 41. Gene Therapy in Erectile Dysfunction 42. Stem and Endothelial Progenitor Cells in Erectile Biology 43. Mechanical, Malleable, and Soft Semi-rigid Penile Implants 44. Inflatable Penile Protheses in Erectile Dysfunction 45. Inflatable Penile Prostheses 46. Design, Development, and Use of Questionnaires and Surveys in the Evaluation and Management of Sexual Dysfunction: Erectile Dysfunction 47. Assessment of Male Ejaculatory Disorders 48. Clinical Trial Design for Erectile Dysfunction 49. Sexual Function in Congential Anomalies 50. Veno-occlusive impotence 51. Penile Fracture Section IV Special Problems 52. Risks, Complications, and Outcomes of Penile Lengthening and Augmentation Procedures 53. Peyronie’s Disease: Evaluation and Medical Treatment 54. Peyronie’s Disease: Surgical Treatment 55. Priapism 56. PDE5 Inhibitor Therapy for Priapism 57. Augmentation of PDE5 Inhibitor Response 59. Diabetic ED 60. Chronic Renal Failure and Sexual Dysfunction 61. Evaluation of Ejaculatory Disorders 62. Medical Treatment of Ejaculatory Dysfunction 63. Topical Agents for the Treatment of Premature Ejaculation 64. Potency Preserving Surgery: Radical Prostatectomy and other Pelvic Surgery 65. Rehabilitation of Sexual Function following Prostatectomy 66. Sexual Dysfunction and Prostate Cancer Therapy 67. Gender Reassignment Surgery

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Book SynopsisSexually transmitted infections remain a global health concern with the World Health Organization reporting over 340 million new cases of bacterial and protozoal STI every year, worldwide. They are frequently associated with a significant degree of medical and psychological morbidity. This full-colour pictorial guide is a unique, single volume compilation of common diseases in genito-urinary medicine. It covers a wide range of ailments from sexually transmitted infections to dermatological conditions affecting the genito-urinary system. Each high-quality image is accompanied by a clear, concise description to aid diagnosis. As well as providing a diagnostic tutorial for trainees in genito-urinary medicine, this book is a reference for any healthcare professional encountering these diseases. Candidates for the Diploma of Genito-urianry Medicine and the Knowledge Based Assessment in Genito-Urinary Medicine will find this visual compendium invaluable.Trade ReviewThe Pictorial Atlas of Common Genito-Urinary Medicine - will be of immense practical 'in the clinic, on the desk' day-to-day use for clinicians working in diverse primary and secondary healthcare settings anywhere in the world. Professor Rob Miller, in the ForewordTable of ContentsForeword. Preface. Acknowledgements. Sources of information. Genitalia. Male internal and external genitalia. Female internal and external genitalia. Syphilis. Neisseria gonorrhoea. Urethritis due to chlamydia trachomatis. Non-specific urethritis. Pelvic inflammatory disease. Prostatitis. Epididymitis and epididymo-orchitis. Reiter's Syndrome. Bacterial vaginosis. Trihomonas vaginalis. Genital candidiasis. Tropical genital and sexually acquired infections. Chancroid. Lymphogranuloma Venereum. Granuloma inguinale. Non-venereal endemic treponematoses. Yaws. Pinta. Bejel. Urinary tract Infection. Genital herpes. Human papillomavirus. Molluscum contagiosum. Sexually acquired viral hepatitis B and C. Scabies. Pediculosis pubis. Dermatoses affecting the genital area. Eczema. Fixed drug eruption. Hair follicles and sebaceous cyst. Lichen nitidus. Lichen planus. Genital psoriasis. Rosai Dorfman Disease. Vitiligo. Herpes zoster. Malignant and pre-malignant conditions affecting the genital area. Erythroplasia of queyrat (Bowen's disease of the glans penis). Extramammary Paget's Disease in the vulval area. Vulval carcinoma. Pseudoepitheliomatous, keratotic and micaceous balanitis. Nodular malignant melanoma of the glans penis. Miscellaneous conditions affecting the genitalia. Epidermoid cyst of the testis. Female circumcision. Fordyce papules. Hypospadias. Epispadias. Necrotising fasciitis. Paraphimosis. Phimosis. Pearly penile papules. Peyronie's Disease. Artificial penile nodules. Plasma cell balanitis. Priapism. Smegma. Urethral caruncle. Urethral diverticulum. Balanitis xerotica obliterans or lichen sclerosus. Vaginismus. Vestibulitis. Vulvodynia. Cervical polyp. Behcet's Disease. Vulvitis. Appendix: SHHAPT codes. Index.

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Book SynopsisPart I. The Kidney.- 1. Kidney: Ultrasound Anatomy and Scanning Methods.- 2. Acute and Chronic Nephropathy.- 3. Ischemic Nephropathy.- 4. Cystic lesions and cystic disease of the kidney.- 5. Kidney Stones.- 6. Solid Renal Masses.- 7. Renal Trauma.- 8. The Transplanted Kidney.- 9. Children's Kidney and Urinary Tract Congenital Anomalies.- 10. Normal and Pathological Adrenal Glands.- 11. Intraoperative Ultrasound in Renal Surgery.- 12. Interventional Ultrasound: Renal Biopsy.- 13. Percutaneous biopsy of renal masses: Rationale, indications, Technique and results.- 14. Focal ablation in Kidney cancer.- 15. Interventional Ultrasound: Positioning Nephrostomy.- 16. Anterograde Approach For Ureteral Catheterization.- 17. Interventional Ultrasound: Puncture and Sclerotherapy of Renal Cysts.- Part II. The Male Pelvis, Ureters and Urethra.- 18. Ultrasound Study of the Ureters and Intrarenal Excretory Tract.- 19. Functional Ultrasound Study of the Upper Excretory Tract.- 20. Ultrasound Study of the Urethra.- 21. Interventional Ultrasound-Guided Treatment of Urinary Incontinence: Insertion of ProACT.- Part III. Prostate and Seminal Vesicles.- 22. Prostate and Seminal Vesicles: Ultrasound Anatomy and Scanning Methods.- 23. Prostatic Inflammation.- 24. Prostatic Cysts.- 25. Benign Prostatic Hypertrophy.- 26. Prostatic Carcinoma.- 27. The Seminal Vesicles: Normal and Pathological Pictures.- 28. Interventional Ultrasound: Transperineal Prostatic Biopsy.- 29. Interventional Ultrasound: Transrectal Prostatic Biopsy.- 30. Ultrasound MRI Fusion Biopsy in Prostate Gland.- 31. PET/TC/PSMA in the diagnosis of prostatic cancer.- 32. Role of Imaging and Biopsy to Assess Local Recurrence After Definitive Treatment for Prostate Carcinoma.- 33. Interventional Ultrasound: Prostatic Biopsy with Special Techniques (Saturation, Template).- 34. Transperineal and Transrectal Biopsy Techniques in Men on Active Surveillance for Early Prostate Cancer.- 35. Interventional Ultrasound: US-Guided Puncture of the Bladder.- 36. Fiducial Marker Implantation in Prostate Radiation Therapy.- 37. Ultrasound Guided Treatment of Prostatic Cancer: Cryoablation.- 38. Ultrasound-Guided Treatment of Prostatic Cancer: Brachytherapy.- 39. Focal therapy in Prostatic Cancer.- Part IV. The Scrotum.- 40. Scrotum: Ultrasound Anatomy and Scanning Methods.- 41. The Testicles: Cystic Lesions.- 42. The Testicles: Solid Lesions.- 43. The Testicles: Trauma, Inflammation and Testicular Torsion.- 44. Varicocele.- 45. Scrotal Masses.- 46. Role of imaging after testicular sparing surgery.- 47. The Role of Intraoperative Ultrasound for Testicular Masses.- Part V. The Penis.- 48. Penis: Ultrasound Anatomy and Scanning Methods.- 49. Penile Color Doppler Ultrasound in the Diagnosis of Erectile Dysfunction.- 50. Penile Ultrasound in Induratio Penis Plastica (IPP).- 51. Penile Trauma and Priapism.- 52. Ultrasound in Infertility Disease.- Part VI. New Technologies.- 53. 3D US.- 54. Elastosonography.- 55. Computerized Artificial Neural Network Analysis of the TRUS (ANNA/C-TRUS).- 56. Contrast ultrasound dispersion imaging.- 57. Micro-ultrasound for the diagnosis and characterization of prostate cancer.- 58. Multiparametric ultrasound of the prostate.- 59. US Contrast Media in Renal Disease.- 60. US Contrast Media in Prostatic Disease.- 61. US Contrast Media in Scrotal Disease.- 62. US Contrast Media in Penile Disease.- 63. US and Arteriovenous Fistulas for Hemodialysis.- 64. US-Assisted Positioning of Central Venous Catheter.- 65. Applications of Ultrasound in Emergency.- 66. Practical Recommendations for Performing Ultrasound Scanning in the Urological and Andrological Fields.- Part VII. The Bladder and Female Pelvic Floor.- 67. Bladder: Ultrasound Anatomy and Scanning Methods.- 68. Neoplastic and Nonneoplastic Disease of the Bladder.- 69. Functional Ultrasound: Assessment of the Weight and Thickness of the Detrusor.- 70. Functional Ultrasound: Functional Female Echo-Dynamic Study.

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Book SynopsisThis book is vital for physicians caring for young patients with urological conditions, as a quick reference book that is easy to read and well-illustrated. Pediatric urological conditions are fairly common, and infants and children are seen on daily basis with urological problems either in clinics or in hospitals. This book is useful to general surgeons, pediatricians, pediatric surgeons, fellows, residents, general physicians and family physicians, medical students and nurses. The Editor has gained experience in the diagnosis and management of various urological problems in infants and children, working in busy hospital over the last 25 years. Trade Review“A useful addition to the bookshelf and in particular to that of speciality trainees (urology or paediatric surgery) who may be undergoing exit exams, due to the pictorial illustrations which may assist with viva practice.” (Neil Featherstone, urologynews, urologynews.uk.com, May, 1, 2018)“This textbook is easy to read and well-illustrated. Each chapter displays many photographs and hand drawn figures. All paediatricians and urologists involved in paediatric surgery will be satisfied with this excellent work, which can be also recommended to trainees.” (European Urology Today, Vol. 29 (4), August-September, 2017)“It encompasses urological development, congenital and acquired problems, most of which are very specific to childhood, renal tumors of childhood, and reaches into areas of pediatric general surgery and gynecology that are proximate to the urological system. … This is a large, well done book that is also a fast and definitive read on all things related to childhood urology. Those looking to get acquainted with these topics or for a rapid, concise review will find this book valuable.” (Robert M. Arensman, Doody's Book Reviews, February, 2017)Table of Contents1. Congenital urological malformations.- 2. Hydronephrosis in infants and children.- 3. Pelviureteric Junction (PUJ) Obstruction.- 4. Renal tumors in children.- 5. Multicystic dysplastic kidney (MCDK).- 6. Congenital ureteral anomalies.- 7. Congenital megaureter.- 8. Vesicoureteral reflux (VUR) in children.- 9. Pediatric urolithiasis.- 10. Persistent Mullerian duct syndrome (PMDS).- 11. Neurogenic bladder sphincter dysfunction.- 12. Urinary tract infection in infants and children.- 13. Bladder exstrophy-epispadias complex.- 14. Megacystis Microcolon Intestinal Hypoperistalsis Syndrome (Berdon syndrome).- 15. Cloacal anomalies.- 16. Urachal remnants.- 17. Inguinal hernia and hydrocele.- 18. Cloacal exstrophy.- 19. Posterior urethral valve.- 20. Utricular cyst (Prostatic utricular cyst).- 21. Hypospadias.- 22. Male circumcision.- 23. Priapism in children.- 24. Undescended testes (Cryptorchidism).- 25. Varicocele.- 26. Testicular torsion and torsion of the testicular or epididymal appendage.- 27. Testicular tumors in children.- 28. Splenogonadal fusion.- 29. Acute scrotum.- 30. Hydrocolpos, vaginal agenesis and atresia.- 31. Disorders of sexual development.

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Book Synopsis- Over 200 exquisite illustrations, ranging from intraoperative photographs, line drawings, diagnostic images, pathology slides, tables and graphs are available to make each case discussed comprehensible and easy to follow. - Traditional and novel therapeutic recommendations are introduced and the latest developments in minimal-access operative techniques are discussed and reviewed. - Focuses on a teamwork oriented approach that identifies the necessary communications amongst the many medical disciplines when dealing with adrenal disorders. Trade ReviewFrom the reviews: "Plenty of thought has been put into the detail of this work … . there is a consistency throughout the book and the chapters are well referenced. The operative technique section is particularly well illustrated … . The chapter on adrenal sparing surgery is both fascinating and thought provoking. … This is a valuable reference book for endocrinologists, radiologists and endocrine surgeons. It is essential reading for the increasing number of surgeons who are gifted in laparoscopic surgery but ignorant about the subject of endocrine surgery … ." (D. Scott-Coombes, The Royal Colleges of Surgeons of Edinburgh and Ireland, Vol. 3 (6), 2005) "An up to date, quite practical but yet comprehensive textbook focused on the field … . From its preface to subject index, this book is really exciting. In my opinion, the very first author’s merit was to approach the problematics of adrenal diseases in a very practical way; Every topic is addressed … by contributors with a well-established experience in the field. … Dimitrios Linos and Jon van Heerden stroke a decisive blow with their state-of-the-art textbook on Adrenal surgery. … endeavour that was well worth their effort." (Etienne Hamoir, Acta Chirurgica Belgica, Vol. 105 (4), 2005) "The various syndromes associated with the adrenal gland are described in great detail and this book brings together a wealth of experience of some extremely rare conditions. There are excellent up-to-date chapters … . The illustrations are clear and the text valuable. All in all, this is an excellent monograph on the surgery of the adrenal glands and is to be recommended to all who have an interest in the management of the rare conditions associated with them." (Richard Collins, Annals of the Royal College of Surgeons of England, Vol. 88, 2006)Table of ContentsHistory of Adrenal Surgery.- Surgical Anatomy.- Hypothalamic-Pituitary-Adrenal Axis.- The Sympathoadrenal System.- The Value of Adrenal Imaging in Adrenal Surgery.- Cushing’s Syndrome.- Subclinical Cushing’s Syndrome.- Ectopic Cushing’s Syndrome.- Cushing’s Syndrome in Children and Adolescents.- Classic Congenital Adrenal Hyperplasia.- Overview of Mineralocorticoid Excess Syndromes.- Primary Aldosteronism: The Surgical Perspective.- Primary Adrenocortical Carcinoma.- Recurrent Adrenocortical Carcinoma.- Metastatic Adrenocortical Carcinoma.- Virilizing and Feminizing Adrenal Tumors.- Pheochromocytoma.- Extra-adrenal and Malignant Pheochromocytoma.- Pheochromocytoma in MEN-2A, MEN-2B, and von Hippel-Lindau Disease.- Benign Paragangliomas.- Neuroblastoma.- Miscellaneous Adrenal Neoplasms (Cysts, Myelolipoma, Hemangioma, Lymphangioma).- Adrenal Incidentalomas.- Clinically Inapparent Adrenal Mass (Incidentaloma or Adrenaloma).- Genetic Syndromes Associated with Adrenal Tumors.- Adrenal Tumors and Pregnancy.- Adrenal-Sparing Surgery.- Anesthesia for Adrenal Surgery.- Open Left Anterior Adrenalectomy.- Open Right Anterior Adrenalectomy.- Open Posterior Adrenalectomy.- Right Anterior Laparoscopic Adrenalectomy.- Left Anterior Laparoscopic Adrenalectomy.- Laparoscopic Lateral Transabdominal Adrenalectomy.- Posterior Retroperitoneoscopic Adrenalectomy.- Laparoscopic Partial Adrenalectomy.- Virtual Reality and Robotic Technologies in Adrenal Surgery.

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Book SynopsisDas Buch informiert über die operative und konservative Therapie sämtlicher Stadien des Harnblasenkrebses. Entsprechend der großen Bedeutung der histologischen Einschätzung der Tumorausbreitung und Bösartigkeit wird die pathologische Anatomie des Harnblasenkarzinoms ausführlich dargestellt. Bei den operativen Verfahren steht die transurethrale Tumorresektion im Vordergrund. Eine Verbesserung der operativen Behandlung, insbesondere der fortgeschrittenen Stadien des Harnblasenkrebses, bieten die Methoden der integrierten Therapie. Hierzu gehören Chemo- und Strahlentherapie, aber auch die neuesten Verfahren wie die lokale Hyperthermie. Insbesondere die komplizierte integrierte Therapie nimmt in dem Buch breiten Raum ein. Bei den Einzeldarstellungen der verschiedenen tragenden Säulen der integrierten Therapie (Operation, Chemotherapie, Strahlenbehandlung und Hyperthermie) wird übergreifend versucht, das Ineinanderspiel der verschiedenen Therapieformen deutlich zu machen. Die Laserbehandlung, die photodynamische Therapie sowie der Stand der Immuntherapie werden ihrer Bedeutung entsprechend abgehandelt. Die praxisnahe, übersichtliche Darstellung des Themas macht das Buch für Urologen und andere, mit dem Problem befaßten Ärzte in Klinik und Praxis zu einem aktuellen Nachschlagewerk und Ratgeber.Table of ContentsEinführung.- Pathologische Anatomie des Harnblasenkarzinoms.- Operative Therapie des Harnblasenkarzinoms (Mit 8 Abbildungen).- Strahlentherapie des Harnblasenkarzinoms.- Systemische Chemotherapie beim metastasierten Harnblasenkarzinom.- Lokale Therapiekonzepte beim Harnblasenkarzinom a) Intravesikale Zytostatikainstillation b) Integrierte Behandlung durch intraarterielle Zytostatikainfusion und transurethrale Hochfrequenzhyperthermie (Mit 12 Abbildungen).- Transurethrale lokale Hochfrequenzhyperthermie des Harnblasenkarzinoms (Mit 9 Abbildungen).- Laserbehandlung von Urogenital-Tumoren (Mit 6 Abbildungen).- Integrale photodynamische Therapie des multifokalen Blasenkarzinoms nach Photosensibilisierung mit Hämatoporphyrinderivat (HpD) (Mit 6 Abbildungen).- Immuntherapie beim Harnblasenkarzinom (Mit 4 Abbildungen).- Glossar der onkologischen Therapie des Harnblasenkarzinoms.

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Book SynopsisThe effect of calcium antagonists on heart muscle and blood circulation is the reason that they have found widespread clinical application for a number of years. Less well known, in contrast, is the effect this group of substances has on the kidneys, both on kidney cells and the blood flow through the kidneys. This effect was the subject of a workshop we organized in Tiibingen in June 1986. Different groups studied the effects of these substances, especially in animals, on the processing of calcium by the kidney cells and on blood flow. A possible explanation is that the calcium antagonists block the influx of calcium through special cell canals, especially the cells of the distal tubule. It is necessary to test whether there is a blockade or only a reduction in the passage of calcium. Our understanding of the effect of calcium antagonists is in large part based on the results of morphologic, physiologic, and pharmacologic studies of calcium in the kidneys. The particular processes involved in nephrocalcinosis are special objects of study with regard to calcium antagonists. This book presents the results of experimental studies of the effect of calcium antagonists on nephrocalcinosis and acute renal failure after ischemia. In this context, the clinician is particularly interested in the use of calcium antagonists to protect against the kidney in urolithiasis, in acute renal failure and during kidney transplantation. The book is thus of interest to urologists and nephrologists as well as pharmacologists. biochemists, physiologists, and others in research.Table of ContentsFundamentals.- Nephron- and Collecting Duct Structure in the Kidney, Rat.- Cellular Mechanisms of Renal Calcium Transport.- Factors Influencing Renal Calcium Excretion.- Ca2+ Antagonists — Mode of Action and Pharmacodynamics.- Nephrocalcinosis and Calcium Antagonists.- Pathological Anatomy, Etiology, and Pathogenesis of Nephrocalcinosis.- Clinical Aspects of Nephrocalcinosis.- Nephrocalcinosis in the Kidney of the Rat on Atherogenic Diet and the Effect of Calcium Antagonists (Nifedipine).- Influence of Calcium Antagonists (Nifedipine) on the Excretion of Calcium and Other Substances Relevant for Stone Formation in Rats with Nephrocalcinosis (Induced by Atherogenic Diet).- The Unique Chemical Composition of Nephrocalcinosis in Experimental Renal Insufficiency, Disturbances of Cellular Calcium Metabolism, and Protective Effect of Verapamil Against Nephrocalcinosis.- Calcium Antagonists in Acute Renal Failure and in Hypertension. Calcium Antagonists in Ischemic Acute Renal Failure (Improvement of Function and Morphologie Damage by Nisoldipine).- Effect of Calcium Antagonist Diltiazem on Acute Renal Failure: Experiments on Animals and Clinical Studies.- Renal Function in Hypertensive Patients and Calcium Entry Blockers.

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Book SynopsisDieser Patientenratgeber richtet sich an Frauen mit Beschwerden und Schmerzen im Bereich von Blase, Darm und Becken, wie Urin- und Stuhlinkontinenz, Entleerungsstörungen von Blase und Darm. Er informiert über die neuen Behandlungsmethoden nach der Integraltheorie, die davon ausgeht, dass die meisten Inkontinenzprobleme ihren Ursprung im Bereich geschädigter bindegewebiger Bänder der Vagina haben und nicht von Blase oder Darm ausgehen. Durch operative Korrektur dieser Strukturen, meist minimal-invasiv, konnte weltweit schon vielen Frauen geholfen werden. Neben einer allgemeinen, für Laien gut verständlichen und illustrierten Einführung in die Anatomie und Funktionsweise der Beckenorgane geben Fallbeispiele weitere Einblicke in die Thematik. Die Autoren hoffen, dass die Lektüre dieses Ratgebers betroffenen Frauen hilft, zusammen mit ihrem Arzt zu entscheiden, welche Maßnahmen für sie die richtigen sind.Trade Review“... Der Ratgeber erklärt ausführlich die Ursachen von Harn- und Stuhlinkontinenz und zeigt die zur Verfügung stehenden Behandlungsmöglichkeiten. Tipps zur Ernährung, dem Umgang mit Inkontinenz im Alltag und Fallbeispiele runden das Werk ab.” (Das PTA Magazin, Heft 5, Mai 2017)Table of ContentsUrsachen für Inkontinenz und Prolaps.- Wie und warum etwas schief geht.- Kurze Übersicht über die Behandlungsmöglichkeiten.- Ist das Ihr Problem? – Schädigung der ventralen Haltebänder.- Verstopfung und Stuhlinkontinenz, Hämorrhoiden und Analfissuren.- Ernährung und Umgang mit Inkontinenz.- Ein typischer Besuch in der Klinik.- Zusammenfassung - „Was tue ich - wohin gehe ich?“.

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Book Synopsis Tipps für eine abgestimmte Behandlung von geriatrisch urologischen PatientenDas Praxisbuch zur Urogeriatrie. Als erster Professor für Urogeriatrie Deutschlands schafft der Autor den Transfer von hilfreichen Erkenntnissen aus der Geriatrie in die Urologie und umgekehrt. Die Zunahme älterer, multimorbider Patienten ist in der Urologie besonders stark. Inkontinenz ist eines der führenden Leiden im höheren Lebensalter. Fachübergreifend, auf der Basis der aktuellen Wissenschaft und einer jahrelangen Erfahrung aus Klinikpraxis und Forschung, werden relevante Aspekte der Geriatrie, die bei der Behandlung multimorbider, urologischer Patienten berücksichtigt werden sollten, übersichtlich und praxisnah erläutert. Dazu zählen Themen wie: Einbinden geriatrischer Assessments in die urologische Diagnostik Einbeziehung der geistigen und körperlichen Ressourcen in die Therapieentscheidung Nebenwirkungen und Wechselwirkungen urologischer Präparate Polypharmazie Demenz und andere Komorbiditäten Kognitive Veränderungen nach einer urologischen Operation Jedes Kapitel enthält Tabellen und Entscheidungshilfen, die es dem Leser erlauben, schnell die wichtigsten Punkte für den geriatrischen Patienten zu prüfen. Für alle Urologen, aber auch Allgemeinmediziner, Internisten, Geriater, die diese Patientengruppe, die eine ganzheitliche Behandlung verfolgen.Das Buch entstand in Zusammenarbeit mit dem Arbeitskreis Geriatrische Urologie. Es möchte durch den fachübergreifenden, interdisziplinären Blick, ein Überdenken standardisierter Therapien anregen. Table of Contents1. Einleitung.- 2. Demographie.- 3. Besonderheiten des geriatrischen Patienten.- 4. Assessment für den Urologen.- 5. Urogeriatrisches Syndrom: Harninkontinenz.- 6. Urogeriatrisches Syndrom: Blasenentleerungsstörung.- 7. Katheterableitung beim geriatrischen Patienten.- 8. Urogeriatrisches Syndrom: Makrohämaturie.- 9. Urogeriatrisches Syndrom: Sturzrisiko.- 10. Urothelkarzinom der Harnblase beim geriatrischen Patienten.- 11. Prostatakarzinom beim geriatrischen Patienten.- 12. Erkrankungen des äußeren Genitales beim Mann.- 13. Harnwegsinfekte beim geriatrischen Patienten.- 14. Delir und urologische Operationen.- 15. Nierenzellkarzinom beim geriatrischen Patienten.- 16. Nächtliches Polyuriesyndrom.- 17. Testosteronmangel im Alter.- 18. Perioperatives Management, Entlassung, Rehabilitation.

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Book SynopsisI Grundlagen der Diagnostik.- II Symptome und Behandlung.- III Nützliches für den Nacht- und Wochenenddienst.

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Book Synopsis

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Book SynopsisTrade Review"From his father's dream of Lester becoming a doctor, this memoir serves as an inspiration for any young medical student to capture their dream. Certain to become a noted source, Lucky Medicine gives us a ground-breaking looking into a mid-western, African American youngster's unlikely journey to become a doctor."—Booker T. Jones, Grammy Award Winner, and Rock and Roll Hall of Fame inductee"Sometimes, change can come with a big ka-BOOM. Other times, it sneaks in the back door and sits quietly. That mixture's what you get with this unique memoir, Lucky Medicine."—Indianapolis RecorderTable of ContentsPrefacePart One: Before1. L.L. Goodman2. (Dis) Integration3. My Son Is Going to Be a Doctor4. A Family Crises Changes the Paradigm5. My Personal Goal6. The End of the Dream?7. Moving On Up, Sort of8. Schooled9. Why Am I So Fortunate?10. A Sixteen-Year-Old Boy's Dream11. Junior Vaudeville12. Saying Goodbye and a Glimpse of My FuturePart Two: Year One, 1961-196213. Your Mama Doesn't Live Here Anymore14. Okay, It's Show Time!15. What's Your Name? Where Are You From?16. What's a Greek?17. A Peek at What Lies Ahead18. The Cleavers or the Bunkers?19. Ray Charles20. A New Low21. Something Really Special22. I'm Terribly Aware of Her Presence23. It's My Turn or Is It?24. What In the World Was That About?25. Let's Try This Again26. Be Careful What You Ask For27. Welcome to the World of the Black Working ClassPart Three: Year Two, 1962-196328. Lickety-split29. Armageddon?30. The Unanticipated Price of Brotherhood31. Life As an Active Becomes Real32. The Elusive 3.0 GPA33. Here Come the Sammies34. Joy and Sorrow Interlaced35. The Horn Sounded and the Walls Came Tumbling Down36. Second Verse Same as the First?37. With Power Comes Responsibility38. The Challenge of the DreamPart Four: Year Three, 1963-196439. If We Cannot Make Our Sun Stand Still, Yet We Will Make Him Run40. WTF?41. September 19th42. The Big Hurt43. The End of Camelot44. Hooray! I'm In!45. The 24 Hour Grill46. Really?47. The Storm Becomes a Hurricane48. The Last Dance49. Branching Out50. Little George51. The Music Man from Memphis52. Something Completely Different53. It's All over but the ShoutingPart Five: After54. ReflectionsEpilogueAcknowledgments

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Book SynopsisTrade Review"From his father's dream of Lester becoming a doctor, this memoir serves as an inspiration for any young medical student to capture their dream. Certain to become a noted source, Lucky Medicine gives us a ground-breaking looking into a mid-western, African American youngster's unlikely journey to become a doctor."—Booker T. Jones, Grammy Award Winner, and Rock and Roll Hall of Fame inductee"Sometimes, change can come with a big ka-BOOM. Other times, it sneaks in the back door and sits quietly. That mixture's what you get with this unique memoir, Lucky Medicine."—Indianapolis RecorderTable of ContentsPrefacePart One: Before1. L.L. Goodman2. (Dis) Integration3. My Son Is Going to Be a Doctor4. A Family Crises Changes the Paradigm5. My Personal Goal6. The End of the Dream?7. Moving On Up, Sort of8. Schooled9. Why Am I So Fortunate?10. A Sixteen-Year-Old Boy's Dream11. Junior Vaudeville12. Saying Goodbye and a Glimpse of My FuturePart Two: Year One, 1961-196213. Your Mama Doesn't Live Here Anymore14. Okay, It's Show Time!15. What's Your Name? Where Are You From?16. What's a Greek?17. A Peek at What Lies Ahead18. The Cleavers or the Bunkers?19. Ray Charles20. A New Low21. Something Really Special22. I'm Terribly Aware of Her Presence23. It's My Turn or Is It?24. What In the World Was That About?25. Let's Try This Again26. Be Careful What You Ask For27. Welcome to the World of the Black Working ClassPart Three: Year Two, 1962-196328. Lickety-split29. Armageddon?30. The Unanticipated Price of Brotherhood31. Life As an Active Becomes Real32. The Elusive 3.0 GPA33. Here Come the Sammies34. Joy and Sorrow Interlaced35. The Horn Sounded and the Walls Came Tumbling Down36. Second Verse Same as the First?37. With Power Comes Responsibility38. The Challenge of the DreamPart Four: Year Three, 1963-196439. If We Cannot Make Our Sun Stand Still, Yet We Will Make Him Run40. WTF?41. September 19th42. The Big Hurt43. The End of Camelot44. Hooray! I'm In!45. The 24 Hour Grill46. Really?47. The Storm Becomes a Hurricane48. The Last Dance49. Branching Out50. Little George51. The Music Man from Memphis52. Something Completely Different53. It's All over but the ShoutingPart Five: After54. ReflectionsEpilogueAcknowledgments

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Book SynopsisFollowing on from the first book entitled 'Conservative treatment of Male Urinary Incontinence and Erectile Dysfunction' this book has been expanded to include seven new chapters and existing chapters have been extensively updated.Trade Review"The glossary of terms is useful and contains many common terms used in the specialty; for the student, it would be helpful to provide clarification of the terms 'nocturia' and 'urgency'." (Physiotherapy Journal, March 2010) "This is a welcome addition to the field and should be of interest to a wide variety of healthcare providers who care for these patients." (Doody's Health Services) "...an essential reference book for physiotherapists working in the field of male pelvic floor disorders …simple layout...." (Association of Psychotherapists in Women's Health, September 2006)Table of ContentsList of Figures xiii List of Tables xvii Preface xix Acknowledgements xxi 1 History of the Male Pelvic Floor 1 Introduction 1 Physiotherapy development 1 Assessment of the male pelvic floor 2 Pelvic floor exercises 3 Posture 3 Detrusor underactivity 3 Detrusor overactivity 4 Nocturnal enuresis 5 Post-prostatectomy incontinence 5 Post-micturition dribble 6 Constipation 6 Faecal incontinence 7 Erectile dysfunction 7 Conclusion 8 2 Lower Urinary Tract Symptoms 9 Male lower urinary tract symptoms 9 Male questionnaires 10 Prevalence of lower urinary tract symptoms 12 Summary 13 3 Anatomy and Physiology of the Lower Urinary Tract 15 Male lower urinary tract 15 Prostate gland 17 Pelvic floor muscles 18 Penis 22 Nerve supply to the urinary system 22 Congenital abnormalities 24 Summary 27 4 Nervous Control of Lower Urinary Tract Function 29 Introduction 29 Urinary continence 29 Micturition cycle 29 Neurological control of the bladder 31 Integral bladder storage and voiding reflexes 33 Summary 35 5 Prostate Conditions and their Treatment 37 Investigations for prostate conditions 37 Benign prostatic hyperplasia 38 Prostate cancer 40 Prostatitis 41 Summary 41 6 Urinary Incontinence 43 Definition of urinary incontinence 43 Prevalence of urinary incontinence in men 43 Incidence of urinary incontinence following transurethral resection of the prostate 44 Incidence of urinary incontinence following radical prostatectomy 44 Classification of lower urinary tract symptoms 45 Storage symptoms 45 Voiding symptoms 47 Post-micturition symptoms 47 Signs suggestive of lower urinary tract dysfunction 47 Urodynamic terminology 50 Summary 51 7 Pelvic Pain in Men 53 Introduction 53 Definitions of pelvic pain 53 Acute pelvic pain 54 Chronic pelvic pain syndromes 54 Penile pain 54 Prostatitis 55 Sexual pain 55 Incidence of pelvic pain 55 Aetiology of acute pelvic pain 56 Aetiology of chronic pelvic pain 57 Assessment of pelvic pain 58 Treatment of acute pelvic pain 58 Treatment of chronic pelvic pain 58 Summary 61 8 Patient Assessment 63 Introduction 63 Subjective assessment 63 Bowel activity 65 Objective assessment 69 Urodynamics 70 Summary 74 9 Conservative Treatment 75 Conservative treatment for men with lower urinary tract symptoms 75 Stress urinary incontinence 77 Urge urinary incontinence 87 Post-prostatectomy incontinence 90 Post-micturition dribble 91 Chronic retention of urine 91 Extra-urethral urinary incontinence 93 Functional incontinence 94 Follow-up treatment 94 Treatment outcomes 94 Prevention of urinary incontinence 94 Pads 94 Appliances 96 Skin care 96 Research opportunities 97 Case studies: Questions and answers 98 Summary 100 10 Literature Review of Treatment before and after Prostatectomy 101 Introduction 101 Literature search 102 Results 103 Conclusions 111 11 Treatment of Post-prostatectomy Patients 113 Introduction 113 Assessment 113 Treatment 114 Post-prostatectomy complications 117 Post-prostatectomy erectile dysfunction 119 Summary 120 Frequently asked questions 120 12 Medication 123 Introduction 123 Pharmacotherapy for detrusor overactivity 124 Pharmacotherapy for stress urinary incontinence 126 Pharmacotherapy for nocturnal enuresis 127 Medication for nocturia 127 Medication which may have an adverse effect on lower urinary tract function 128 Medication which reduces the size of the prostate gland 130 Medication which relaxes the smooth muscle of the bladder neck 130 Medication for prostate cancer 130 Medication for hypocontractile bladder 131 Medication for erectile dysfunction 131 Medication which changes the colour of the urine 131 Summary 131 13 Faecal Incontinence 133 Introduction 133 Digestive system 133 Defaecation 134 Pelvic floor muscles 134 Causes of faecal leakage 137 Treatment for faecal leakage 138 Summary 144 14 Male Sexual Dysfunction 145 Introduction 145 Low libido 145 Erectile dysfunction 146 Orgasmic and ejaculatory disorders 153 Anorgasmia 154 Anejaculation 154 Retrograde ejaculation 155 Retarded ejaculation 156 Premature ejaculation 157 Aspermia 158 Haemospermia 158 Low-volume ejaculate 159 Painful ejaculation 159 Anhedonia 159 Sexual pain 160 Summary 160 15 Treatment of Male Sexual Dysfunction 161 Introduction 161 Low libido 161 Erectile dysfunction 162 Literature review of physical therapy for erectile dysfunction 163 Premature ejaculation 174 Conclusions 176 16 Setting up a Continence Service 177 Introduction 177 Integrated continence services 177 Director of continence services 179 Contacts for specialist groups 182 Suppliers 183 Helplines for men in the UK 183 Books and videos for professionals 185 Books for patients 186 Video for patients 187 Summary 187 Appendix: Male Continence Assessment Form 189 Glossary 197 References 201 Index 217

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Book SynopsisSexual and Reproductive Health at a Glance provides a highly-illustrated, visual introduction to all aspects of sexual and reproductive health, from basic clinical examination skills to the management of acute Sexually Transmitted Infections (STIs) and unplanned pregnancy.Table of ContentsPreface vii Acknowledgements viii Abbreviations ix How to use your textbook xi About the companion website xii 1 Sexual and reproductive health fundamentals 2 Part 1 Principles of sexual and reproductive health 1 Part 2 Contraception 11 Part 3 Sexual health 43 2 Combined hormonal contraception 12 3 Progestogen-only contraceptives 16 4 Intrauterine contraception 22 5 Barrier methods 26 6 Fertility awareness methods 28 7 Emergency contraception 30 8 Male and female sterilization 32 9 Contraception for specific groups of individuals 36 10 Chlamydia trachomatis 44 11 Gonorrhoea and non-gonococcal urethritis 46 12 Vaginal discharge 50 13 Bacterial vaginosis 52 14 Vulvovaginal candidiasis 54 15 Trichomonas vaginalis 56 16 Syphilis 58 17 Genital herpes 64 18 Genital ulcers: tropical infections 68 19 Epididymo-orchitis and sexually-acquired reactive arthritis 72 20 Molluscum contagiosum and normal genital lumps 74 21 Anogenital warts and human papilloma virus infection 76 22 Genital infestations 80 23 Anogenital dermatoses 82 24 Viral hepatitis A, B and C 84 25 HIV 86 26 Sexual assault 90 Part 4 Reproductive health 93 27 Abortion 94 28 Abnormal uterine bleeding 100 29 Menstrual problems 102 30 Gynaecological problems in SRH 104 31 Pelvic inflammatory disease 106 32 Menopause 108 33 Sexual problems 110 Index 112

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Book SynopsisManaging urologic cancer by preserving, as opposed to removing, affected tissue, is rapidly becoming the favoured choice for urologists and oncologists. Discover all available options and how to achieve the best possible patient management with this expert guide to the area. The editor, Mark Schoenberg, is an internationally-renown expert in this exciting new area and has recruited an outstanding team featuring some of the leading urologists/oncologists in North America and Europe to assist him.Table of ContentsList of Contributors xiii Preface xvii Cancer Genetics, Cancer Biology, and Tumor Growth and Metastasis: The Interaction of Cancer and Its Host Environment 1Mark C. Markowski and Kenneth J. Pienta Renal Cell Carcinoma 1 Bladder Cancer 3 Prostate Cancer 6 References 12 Pathological Basis of Tumor Characterization: Cytopathology, Surgical Pathology, and How Histo]Morphology Informs Treatment Decision Making 19Oleksandr N. Kryvenko and Fadi Brimo The Kidney 23 The Urothelium 27 The Testis 29 References 30 The Immunobiology of Tumor Ablation 33Rafi Kabarriti and Chandan Guha Manipulating the Immune System to Fight Cancer 33 Can We Take Advantage of Ablative Therapies to Activate the Immune System? 34 Immunomodulatory Properties of HIFU 35 Immunomodulatory Properties of Cryotherapy 36 Immunomodulatory Properties of Radiation Therapy 37 References 38 Computed Tomography of Urologic Malignancies: The Role of MDCT in Renal Cell Carcinoma and Transitional Cell Carcinoma 41Siva P. Raman and Elliot K. Fishman Introduction 41 MDCT Protocol Design 41 Three]Dimensional Reconstructions 44 Neoplasms of the Intrarenal Collecting Systems, Ureters, and Bladder 45 Solid Renal Parenchymal Lesions 49 Conclusion 55 References 55 MRI and Metabolic Imaging 59Louise Dickinson, Francesco Fraioli, Athar Haroon, and Clare Allen Magnetic Resonance Imaging 59 MRI Sequences 59 Clinical Applications of MRI for Prostate Cancer 61 Clinical Applications of MRI for Renal Cancer 63 Clinical Applications of MRI for Bladder Cancer 64 New Advances in MRI 65 Metabolic Imaging 66 Clinical Applications of PET–CT for Prostate Cancer 69 Active Surveillance for Low]Risk Prostate Cancer 113Laurence Klotz Introduction and Background 113 Rationale 113 Genetic Features of Low]Grade Prostate Cancer 114 Metastatic Potential 115 Limitations of PSA Kinetics 116 Role of MRI 116 Implications for Patient Management 117 Eligibility for Surveillance 118 Outcome of Surveillance 119 Modeling 119 AS in Practice 121 Conclusions 121 References 122 Tissue]Preserving Surgical Approaches in Urologic Oncology: The Therapeutic Mechanism for Tumor Ablation 127Ganesh Kartha and J. Stephen Jones Introduction 127 Cryoablation: Extreme Cold for Tumor Necrosis 128 Conclusion 130 References 130 Focal Therapy for Prostate Cancer: An Evidence]Based Approach to Tissue]Preserving Strategies 133Kara L. Watts, Yaalini Shanmugabavan, Victoria Chernyak, and Hashim Uddin Ahmed Introduction 133 Key Concepts in FT for PCa 134 Tissue]Preserving FTs 135 Cryotherapy 135 HIFU 137 Salvage Focal/Hemiablation HIFU 140 IRE 141 Radiation 142 Additional Therapies 143 Implications for Research 144 Conclusions 144 References 145 The Modern Basis for Nephron]Sparing Surgery in Patients with Renal Cancer: Biologic Heterogeneity, the Significance of Tumor Biopsy, and the Changing Roles of Partial Nephrectomy and Tumor Ablation 151Jeffrey J. Tomaszewski, Robert G. Uzzo, and David Y.T. Chen Introduction 151 Principal Treatment Options for SRMs and the Basis for Nephron Preservation 152 Comparative Effectiveness of Radical versus NSS 153 Rationale for Ablative Therapies 154 Treatment Trends for Stage I RCC 157 The Role of RMB 158 Challenges Posed by Intratumoral Heterogeneity 161 Conclusions 161 References 162 Bladder]Preserving Strategies in the Treatment of Urothelial Cancer: The Disease Spectrum and the Dawn of Molecular Surgical Guidance 169Stephan Kruck and Arnulf Stenzl Augmented Cystoscopy 170 Fiber]Optic Probe Technology 171 Conclusion 172 References 172 Image]Guided Thermal Ablation of Adrenal Malignancies 175Kyungmouk Steve Lee, Bradley B. Pua, and Stephen B. Solomon Introduction 175 Clinical Results 175 Preprocedural Evaluation 176 Technical Considerations 178 RFA 178 Microwave Ablation 179 Cryoablation 180 Complications 180 Follow]up 181 Conclusion 182 References 182 Managing Penile Cancer: Integrating Tissue Preservation, Energy]Based Therapeutics, and Surgical Reconstruction 185Arthur L. Burnett Introduction 185 Description 186 Diagnosis and Staging 186 Treatment 189 References 193 Testis Cancer: Testis]Sparing Cancer Surgery 199Nilay M. Gandhi and Pravin K. Rao Introduction 199 Imaging of Testicular Tumors 199 Bilateral Tumors 201 The Advent of Testis]Sparing Surgery 201 Concerns about TSS 201 Indications for TSS 204 Preoperative Considerations and Surgical Technique 204 Postoperative Care and Follow]Up 207 Considerations Regarding Surgical Technique 207 Outcomes of TSS 208 Summary 209 References 210 Nanotechnology: An Evolution in Tissue Preservation and Focal]Targeted Oncologic Therapy 213Kara L. Watts and Joshua M. Stern Introduction 213 Introduction to Nanotechnology 214 Types of Nanoparticles 214 Delivery and Use of Nanoparticles 217 Nanotechnology in Prostate Cancer 219 Imaging in Prostate Cancer 219 Therapeutics in Prostate Cancer 221 Nanotechnology in Renal Cancer 223 Nanotechnology in Other Urologic Cancers 224 Limitations of Nanoparticles 224 Future Directions and Conclusions 225 References 226 Trial Design Issues in the Study of Focal Therapy in Prostate and Kidney Cancer 233John B. Eifler and David F. Penson Issues around Endpoints in Studies of Focal Therapy 234 Issues around Defining the Study Population and the Control Arms of Comparative Studies in Focal Therapy 237 Issues around Selecting the Optimal Study Design in Focal Therapy 238 Conclusion 238 References 239 Index 000

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Book SynopsisA Clinical Guide to Urologic Emergencies A Clinical Guide to Urologic EmergenciesAn ageing population and a predicted shortfall in the number of urologists means that, increasingly, the management of complex urological problems will fall to hospital emergency departments and the surgeries of primary care physicians. With many doctors and medical students now having less exposure to urology, there is a real and urgent need for accessible and practical guidance in managing urologic emergencies. A Clinical Guide to Urologic Emergencies offers practical guidance to the best practices in diagnosis, treatment and management of patients with urgent urological conditions. Designed to be an extremely useful tool to consult in the clinical setting, it will be a vital source of information and guidance for all clinicians, irrespective of their level of urologic knowledge. Edited by an outstanding international editor team, this book is particularly aimed at physicians, advanced practice proviTable of ContentsContributors Preface SECTION 1 Upper Urinary Tract 1 Blunt Renal Injuries Lindsay Hampson and Nnenaya Mmonu 2 Penetrating Renal Trauma – A Civilian and Military Perspective Jonathan Wingate 3 Renal Infections Brusabhanu Nayak, Nitin Srivastava, and Rajeev Kumar 4 Acute Kidney Stone Management Justin S. Ahn and Jonathan D. Harper 5 Traumatic Adrenal Hemorrhage Hong Truong and Bradley D. Figler 6 External Ureteral Trauma Humberto G. Villarreal and Steven J. Hudak 7 Iatrogenic Ureteral injury Haruaki Kato, Kazuyoshi Iijima, Tomohiko Oguchi, Seiji Yano SECTION 2 Lower Urinary Tract 8 Bladder Injuries Yosuke Nakajima 9 TRAUMATIC URETHRAL INJURIES Laura G. Velarde and Reynaldo G. Gómez 10 Acute management of urethral stricture Akio Horiguchi 11 PROSTATITIS AND PROSTATIC ABSCESS Hunter Wessells SECTION 3 External Genitalia 12 Fournier’s Gangrene Kosuke Kitamura and Shigeo Horie 13 Traumatic Penile Injuries Ariel Fredrick and Alex J. Vann 14 Priapism Akash A. Kapadia, Kevin Ostrowski and Thomas J. Walsh 15 Traumatic Scrotal and Testicular Injuries Marios Hadjipavlou and Davendra Sharm 16 Testicular Torsion Alexander J. Skokan and Dana A. Weiss 17 Epididymitis and Orchitis Norman Zambrano SECTION 4 Pediatric 18 Urologic Neonatal Emergencies Nicolas Fernandez and Nayib Fakih Index

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