Rheumatology Books

Book SynopsisRheumatology: A clinical handbook is an essential resource for medical students who need an introduction, understanding and overview of the subject. Most competing texts either burden medical students with information they do not require, or cover rheumatology alongside orthopaedics and as a result compromise fundamentals of rheumatology. This book is different: It provides all the information students need during their rheumatology placement Further information resources are signposted for those who want to take their studies further A definition and brief pathophysiology for each condition is provided, which is linked to the respective clinical features. The book covers the core elements of diagnosis and treatment based on the latest national guidelines to swiftly bring students and junior doctors in training up-to-date. Self-assessment questions and an OSCE chapter provide a way of checking that users have understood and grasped the core material, as well as enabling students to be well equipped for their written and OSCE examinations. Written by two medical students and an experienced consultant rheumatologist, the book combines a reader-friendly writing style with coverage of the material through clinical experience of a professional in the field. Printed in full colour throughout, with an attractive design, a clear and concise writing style as well as a range of pedagogical features including an array of mnemonics, pictures and diagrams, Rheumatology: A clinical handbook is exactly the sort of book medical students and newly qualified doctors would benefit from.Trade ReviewFive-star reviews: Brilliant guide for any medical student! "This book is a fantastic guide for any medical student wanting a concise and student friendly source for everything rheumatology! The layout of the information as well as the pictures and little tips provided on how to go about this subject has been extremely helpful. The book is divided into sections making it easy to catagorise the information, I would definitely recommend it as a read if you're struggling with rheumatology." Amazon reviewer Best rheumatology guide for medical students "I used this book for my musculoskeletal rotation and I strongly recommend it. I didn't even have to make notes from this book but simply read it a few times as it includes all salient up to date information in a very easy to follow colourful format without unnecessary paragraphs of information like in many other textbooks. The student friendly features are topped off with exam styled questions making this arguably the best rheumatology read out there for medical students." Amazon reviewer Brilliant! "I am a medical student and this is the best Rheumatology book I've found. It's very clear and concise with all of the conditions you need to know without waffling. It also contains a useful section about investigations and medication. I previously found Rheumatology to be confusing but thanks to this book it now seems much clearer!" Amazon reviewer An essential textbook for all medical students "I'm surprised there aren't more medical revision guides like this. The book is really student friendly - the content is straight to the point and I really like the use of boxes, diagrams and pictures. I would definately recommend this book to any student undergoing their rheumatology rotation." Amazon reviewer To the point "Very informative and concise, good resource for medical students. Gives all the relevant information in a clear and easy to understand format. I epecially like the "OSCE tips boxes". Very handy for quick reference on the wards." Amazon reviewer Five Stars "Excellent layout. Clear, concise and informative condition summaries, plenty of images and self-assessment. Must-read for all Medical Students" Amazon reviewer Very easy to understand and useful! "For me this book ticks all of the boxes for being a fine modular text. I was completely lost when it came to rheumatology before I picked up this book. It provides you with a lot of high quality information but in a way that is easy to digest. The best feature that sets this book apart from other rheumatology or orthopaedics/rheumatology books is the use of modern features such as a bullet point format, good use of colour and lots of mneumonics, tables and diagrams. The book also being new and up-to-date includes the latest national guidelines in rheumatology and saves me having to search through pages and pages of NICE guidance for instance. Finally the book being small and light makes it practical to carry on wards and clinics. The only downside is that it is a touch pricy for a modular text, but having said that I highly recommend this text for anyone undergoing their rheumatology rotations." Amazon reviewer Wonderful! "A fantastic book, well written and full of wonderful pictures, tables and diagrams. All the pertient information without the waffle! I can't wait to see what else they bring out." Amazon reviewer I have been using this book for my rheumatology placement and it's been really useful! "I'm a very visual learner so I love the fact that it is colourful and concise. I think there is the right amount of information and the tables and diagrams make everything very easy to understand especially as rheumatology is such a tricky specialty that requires knowledge of every other system." Amazon reviewer Small book, concise, really helpful "I recently stated working as a Sonographer in Rheumatology and have found this book an excellent source of information in a small, concise format - thank you" Amazon reviewer Excellent "Excellent book - so clear and a good basis to build on." Amazon reviewer I loved this book "This book [has] very good explanation, easy to understand and remember.Well pictured and structured. The author wrote this book absolutely in that way what I was looking for. Highly recommended!" Amazon reviewer Five Stars "Really helpful for the exam, well written, informative and precise" Amazon reviewer Five Stars "Excellent book for grasping rheumatology as a medical student. Clear, concise and well explained information." Amazon reviewer Genuinely Helpful "I am really happy about my purchase of this book. It's a really nice and easy read, pitched at the perfect level for a medical student like myself. In addition to its easy-to-read layout, i found the diagrams to be extremely helpful and clear. The pictures used and the use of colour is a welcome bonus as well. The OSCE chapter as well as the online access to SBA questions with detailed answers are particularly useful for exams." Amazon reviewerTable of Contents1. INTRODUCTION 2. SPECIFIC CONDITIONS Rheumatoid arthritis (RA); Osteoarthritis (OA); Septic arthritis; Introduction to spondyloarthropathies: Psoriatic arthritis (PsA); Ankylosing spondylitis; Reactive arthritis; Gout; Calcium pyrophosphate disease (CPPD); Vasculitis; Giant cell arteritis (GCA); Polymyalgia rheumatica (PMR); SLE; Polymyositis and dermatomyositis; Sjögren's syndrome; Scleroderma; Fibromyalgia; Osteoporosis; Paget's disease 3. PAEDIATRIC RHEUMATOLOGY CONDITIONS Vitamin D deficiency; Juvenile idiopathic arthritis 4. INVESTIGATIONS Blood tests; Immunological tests; Synovial fluid analysis; Imaging 5. PHARMACOLOGY Analgesia; Corticosteroids; Osteoporosis drugs; DMARDs and biological agents 6. OSCEs History taking; Examination; Differential diagnosis Appendix A: Answers to self-assessment questions Appendix B: Photograph acknowledgements

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Book SynopsisFreshly jacketed massmarket edition of this bestselling guide to beating arthritis through nutrition. With over 60 delicious recipes from cook Marguerite Patten, who completely eased her own painful arthritic symptoms through diet, and a comprehensive self-treatment plan from nutritionist Jeannette Ewin.Marguerite Patten suffered from crippling arthritis, but was completely eased of her painful symptoms after following Giraud Campbell's original classic arthritis diet, The New Doctor's Proven Home Cure for Arthritis.However, as a cook she found the recipes impractical and often unpalatable- so she set about creating a whole new set of easy to prepare, good to eat, arthritis-beating recipes.The 60 delicious recipes are accompanied by a nutritional plan devised by Harvard medical School trained nutrition expert and author Jeannette EwinTrade Review “All in all this book is compelling, readable, practical and workable. I recommend it highly.” Suzannah Oliver in ‘Positive Health’, November 2001 ‘I was given your book for my 89th birthday… I have followed your advice and now 4 months later I have given up painkillers. It is truly wonderful to be free from pain and go about my household duties, my garden and daily walks with pleasure again. It’s a joy to get out of bed. My heartfelt thanks to God and you who have brought about this miracle. If only more people would believe in you both.’Mrs Mary Cope

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Book SynopsisNew, medically and nutritionaly updated edition of the classic million-selling arthritis self-help book. This was the original diet that Marguerite Patten followed (author of our 2001 hit, Eat to Beat Arthritis).Without this book I would not be walking today Marguerite Patten, O.B.E.This book has cured arthritic pain for millions of people worldwide. It's also quite an old text now so we have responded to the requests of readers and sales reps suggestions by updating the book's medical and nutritional advice so that it's totally authoritative and also the recipes are more palettable for today's arthritis sufferer.Doctor''s Home Cure for Arthritis is a seven day action plan designed to provide relief from arthritic pain and in the longer term to heal arthritis. Based on dietary change, the programme eliminates many processed foods, (includeing caffeine and alcohol) and replaces these with foods of special benefit to arthritis sufferers.Now fully revised by respected Harvard nutritionisTrade ReviewSome reader comments from Amazon: !Within days the swelling in her knees went down and her mobility returned. So impressed was one of her friends that they are now trying the diet. Certainly one to buy if you are suffering. A reader in Midhurst, UK. This book has changed my Mum's life! in the last 6 months her arthritis became so bad she's been virtually immobile -- she was scared she was looking at life as an invalid!Then a friend showed her this book. Mum and Dad have both been following the plan for 3 weeks -- the results have been terrific: Mum went for a 2 mile walk this morning and can move her hands almost normally and, as an added bonus, between them they have lost 1stone 10lbs. Mum said she started to feel an improvement in the arthritis from day 4 of following the eating plan and the improvement is continuing every day. A reader in Buckinghamshire, UK.

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Book SynopsisIn this volume, the authors describe a rational and evidence-based approach to the integrative therapy of rheumatologic, allergic, and autoimmune disorders, integrating the principles of alternative and complementary therapies into the principles and practice of conventional medical therapy. The authors examine what works and what doesn''t and offer practical guidelines for physicians for incorporating integrative medicine into their practice and advising patients on reasonable and effective therapies. The text discusses areas of controversy and identifies areas of uncertainty where future research is needed. Chapters cite the best available evidence for both safety and efficacy of all therapies discussed. Information will be presented in accessible and easy-to-read formats, including clinical pearls, case histories, and key points, with a second text color for highlighting key information.Trade ReviewThis beautifully produced volume was not only a pleasure to handle but also a real pleasure to read. * International Musculoskeletal Medicine *

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Book SynopsisSjögren's Syndrome summarises current understanding of the pathogenesis of the disease, including advances in the genetics, disease mechanisms, clinical diagnosis and assessment, secondary Sjögren's syndrome, and the role of laboratory investigations and imaging.Trade ReviewThe volume contains well written, succinct, and comprehensive chapters on disease mechanisms, diagnosis, assessments, and laboratory investigations. The layout is pleasing, and each chapter has key points highlighted at the beginning. Chapters are easy to read with useful subheadings and plenty of summary tables and figures showing important mechanisms and pathways of care. This book is indispensable for all interested and involved in the care of the patients with Sjögren's syndrome. * Dr. Vinod Ravindran, Indian Journal of Rheumatology *

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Book SynopsisA practical, comprehensive guide to all aspects of practice in the field. Taking into account the latest evidence, it is well illustrated and written in a clear and concise style, providing both the qualified practitioner and the nursing student with the information they need.Trade ReviewReview from previous edition This handbook presents a concise overview of select disorders in an easy-to-use format. * Doody's Review *For those of you at the beginning of your journey into orthopaedic nursing, use this book to acquire knowledge and answer your questions. For those already well in to this journey, read, think, question, and apply appropriately toe wisdom inherent in every page of this handbook. * Peter Davis MBE, Emeritus Editor, International Journal of Orthopaedic and Trauma Nursing, Associate Professor, University of Nottingham *Table of Contents1: Introduction 2: Musculoskeletal anatomy and physiology 3: Assessment of the musculoskeletal system 4: General principles of care 5: Complications 6: Musculoskeletal conditions 7: Elective interventions 8: Musculoskeletal trauma care 9: Injury management 10: Regional musculoskeletal injuries Appendix

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Book SynopsisSkeletal Muscle Mechanics: From Mechanisms to Function summarises the variety of approaches used by todaya s scientist to understand muscle function and the mechanisms of contraction. This book contains research by leading scientists from numerous fields using many different scientific techniques.Table of ContentsPartial table of contents: MECHANISMS OF MUSCLE CONTRACTION. Considerations on the Mechanisms of Muscular Contraction (W. Herzog). Cross-bridge Action: Present Views, Prospects, and Unknowns (A. Huxley). THEORETICAL MODELLING OF MUSCLE AND MUSCLE CONTRACTION. Considerations on the Theoretical Modelling of Skeletal Muscle Contraction (W. Herzog). The Two-state Cross-bridge Model as a Link Between Molecular and Macroscopic Muscle Mechanics (G. Zahalak). Three-dimensional Geometric Model of Skeletal Muscle (R. Lemos, et al.). IN VIVO MUSCLE FUNCTION (HUMAN). Considerations on In Vivo Muscle Function (W. Herzog). In Vivo Mechanics of Maximum Isometric Muscle Contraction in Man: Implications for Modelling-based Estimates of Muscle Specific Tension (C. Maganaris & V. Baltzopoulos). Muscle Inhibition and Functional Deficiencies Associated with Knee Pathologies (E. Suter & W. Herzog). Effects of Ageing on Eccentric and Concentric Muscle Torque Production in Lower and Upper Limbs (A. Vandervoort, et al.). IN VIVO MUSCLE FUNCTION (ANIMAL). In Vivo Function and Functional Design in Steady Swimming Fish Muscle (S. Katz & R. Shadwick). Visco-Elastic Properties of Cardiac Trabeculae: Re-examination of Diastole (B. Stuyvers, et al.). Index.

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Book SynopsisThis text assesses the role of dendritic cells, T and B lymphocytes, epithelial and mast cells, eosinophils, neutrophils, macrophages, and their products in the initiation and progression of airway inflammation, regulation, and repair. It unveils advances in immunology and cell biology to generate new therapeutic regimens for inflammatory and allergic diseases,and offers unparalleled research from nearly 60 international contributors.Table of ContentsThe cells of the pulmonary immune response: overview of the pulmonary immune response, Laurent P. Nicod; antigen-presenting cells, Henk C. Hoogsteden, Hamida Hammad, and Bart N. Lambrecht; CD4 T lymphocytes in allergic asthma, Mark Larche and A.B. Kay; B-Cell differentiation and IgE synthesis, Hamida Hammad and Bart N. Lambrecht; immune functions of mast cells and basophils, Sarbjit S. Saini; immune functions of human eosinophils, Paul J. Coffer, Patricia M. R.E. Silva, Marco A. Martins, and Leo Koenderman; immune functions of airway epithelium, Sundeep S. Salvi and Stephen T. Holgate. Regulation processes in the pulmonary immune response: tolerance to inhaled antigen, Elizabeth R. Jarman, Gerard F. Hoyne and Jonathan R. Lamb; sensitization to inhaled allergen, Susan L. Prescott; polarization of T-helper cells, Martien L. Kapsenberg, Eddy A. Wierenga, Pawel Kalinski and Esther C. De Jong; CD28 and B7 superfamily members - costimulation and regulation of T-cell function, Anthony J. Coyle, Stephen Manning, and Jose-Carlos Gutierrez-Ramos; control of lymphocyte trafficking through the lung, Reinhard Pabst and Thomas Tschernig; neuroimmune interactions in the pathogenesis of allergic asthma, Armin Braun, Wolfgang A. Nockher, and Harald Renz. Integrated immunology of airway inflammation: immunopathology of atopic and nonatopic asthma, Marc Humbert, Sun Ying, and Douglas S. Robinson; immunology of eosinophilic airway inflammation - what the animal models teach us, Bart N. Lambrecht, Leonie S. Van Rijt, and Harmjan Kuipers; regulation of cellular traffic in the asthmatic lung, Clare M. Lloyd and Jose-Carlos Gutierrez-Ramos; cytokine regulation of bronchial hyperresponsiveness, Johan C. Kips and Romain A. Pauwels; immunological functions of inflammatory mediators, Domenico Spina, Clive Page, Anthony P. Sampson, and Zuzana Diamant; virally induced eosinophilic airway inflammation, Wieslawa Olszewska and Peter J.M. Openshaw; airway remodelling as the outcome of a chronic immu

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Book SynopsisGeorge Tsokos and a panel of authoritative clinicians and researchers synthesize the latest findings from across cell and molecular biology with the basic principles of rheumatology to create the first textbook of molecular rheumatology.Trade Review"Unlike previous classical textbooks of rheumatology in which the clinical and therapeutic approaches to rheumatic disease are discussed, this one is unique in the contributors' ability to integrate the clinical approach to rheumatic disease with the latest biochemical, cellular, and molecular mechanisms at play in these disorders. This approach allows clinical rheumatologists to gain a better understanding of the cellular and molecular biology that underlies the diseases we treat and the therapeutics we use to treat these disorders.."-Doody's Health Science Book Review Journal "It contains many figures of good quality." - Journal of Endocrine Genetics "Unlike previous classical textbooks of rheumatology in which the clinical and therapeutic approaches to rheumatic disease are discussed, this one is unique in the contributors' ability to integrate the clinical approach to rheumatic disease with the latest biochemical, cellular, and molecular mechanisms at play in these disorders. This approach allows clinical rheumatologists to gain a better understanding of the cellular and molecular biology that underlies the diseases we treat and the therapeutics we use to treat these disorders." - Doody PublishingTable of ContentsPart I. Molecular Mechanisms in Rheumatic Diseases Genetics Peter K. Gregersen Viruses Andras Perl Apoptosis John D. Mountz, Hui-Chen Hsu, Huang-Ge Zhang, and Tong Zhou Humoral Response Gary S. Gilkeson T-Cell Signaling Gary A. Koretzky and Erik J. Peterson Adhesion and Costimulatory Molecules Vassiliki A. Boussiotis, Gordon J. Freeman, and Lee M. Nadler Transcription Factors Henry K. Wong Immune Complexes Mark H. Wener Complement V. Michael Holers Eicosanoids and Other Bioactive Lipids Leslie J. Crofford Collagens Sergio A. Jiménez Part II. Cellular Mechanisms in Rheumatic Diseases T-Lymphocytes Nilamadhab Mishra and Gary M. Kammer B-Lymphocytes Robert F. Ashman Monocytes and Macrophages James M. K. Chan and Sharon M. Wahl Polymorphonuclear Cells Michael H. Pillinger, Pamela B. Rosenthal, and Bruce N. Cronstein Synoviocytes David E. Yocum Chondrocytes Tariq M. Haqqi, Donald D. Anthony, and Charles J. Malemud Osteoblasts and Osteoclasts Stavros C. Manolagas Animal Models Thomas J. Lang and Charles S. Via Part III. Pathogenesis of Rheumatic Diseases Systemic Lupus Erythematosus Stamatis-Nick C. Liossis and George C. Tsokos Rheumatoid Arthritis Richard M. Pope and Harris Perlman Inflammatory Myopathies Norbert Goebels and Reinhard Hohlfeld Systemic Sclerosis Timothy M. Wright Vasculitis Jörg J. Goronzy and Cornelia M. Weyand Osteoarthritis Robin Poole and Ginette Webb Osteoporosis Stavros C. Manolagas Heritable Disorders of Connective Tissue Petros Tsipouras Part IV. Molecular Aspects of Treatment of RheumaticDiseases Corticosteroids Henry K. Wong and George C. Tsokos Cytotoxic Drugs David A. Fox and W. Joseph McCune Complement Inhibitors Savvas C. Makrides Cytokine Response Modifiers Richard E. Jones and Larry W. Moreland Restoration of Immune Tolerance Woodruff Emlen Metalloproteases and Their Modulation as Treatment in Osteoarthritis Johanne Martel-Pelletier, Ginette Tardif, Julio Fernandes, and Jean-Pierre Pelletier Gene Therapy Robert P. Kimberly

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Book SynopsisCertain diseases may involve organ systems that cross the boundaries of specialties. For instance, a patient with scleroderma can develop interstitial lung disease, or a patient with relapsing polychondritis can have the clinical manifestation of subglottic stenosis. This book represents a collaboration between specialties, helping clinicians recognize the implications of disease both within their own specialty and in the overlapping specialty. Here, leading experts from the fields of rheumatology and pulmonology provide a masterclass in the care of patients with systemic illnesses that involve the immune system and the lungs.Key Features: Provides an evidence-based clinical approach to the patient with pulmonary manifestations of rheumatic disease Details cutting-edge research with input from the worldâs leading experts Discusses possible future directions for research and advancement

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Book SynopsisInterdisciplinary Rheumatology: Rheumatology and Gastroenterology is the first complete textbook to examine the myriad complications of rheumatic syndromes in the gastrointestinal tract. Each disease is summarized for a broad medical audience, with focus on the consequences of the disorder throughout the gut. The reader will formulate an understanding of the clinical, pharmacological, and nutritional aspects of the interface of these two specialties with expert contributors from a range of academic centers. Rheumatologists and gastroenterologists will be able to recognize, evaluate, and treat gastrointestinal symptoms of autoimmune diseases and collaborate in improving the experience and outcomes of these complex patients.

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Book SynopsisBONE AND JOINT INFECTIONS Explore this comprehensive presentation of bone and joint infections, including non-implant and implant-associated orthopedic infectionsIn the newly revised Second Edition of Bone and Joint Infections: From Microbiology to Diagnostics and Treatment, accomplished researcher and author Werner Zimmerli delivers a comprehensive overview of the most recent developments in the subject of bone and joint infection. Covering much of the new information appearing over the last five years, the book includes four new chapters presenting the diagnostic approach in bone and joint infections, discussing the identification of pathogens by non-culture techniques, management of multi-resistant bacteria in bone and joint infections by bacteriophages, and unusual microorganisms in periprosthetic joint infections.Many of the chapters are also updated to include new information on topics like eubacterial PCR, multiplex PCR, and the shotgun metagenomicsTable of ContentsList of Contributors xii Preface to the Second Edition xvi Foreword to the First Edition xvii Acknowledgments xix Chapter 1 Introduction 1Werner Zimmerli Chapter 2 Diagnostic Approach in Bone and Joint Infections 5Nora Renz, Donara Margaryan, and Andrej Trampuz Introduction 5 Common Microorganisms Causing Bone and Joint Infection 7 Diagnostic Approach in Spinal Infection 8 Diagnostic Approach in Bone Fixation Device‐Associated Infection 10 Diagnostic Approach in Native Arthritis and Infections after Anterior Cruciate Ligament Repair (ACL‐R) 12 Diagnostic Approach in Periprosthetic Joint Infections (PJI) 15 Key Points 17 References 17 Chapter 3 Unusual Microorganisms in Periprosthetic Joint Infection 21Camelia Marculescu and Werner Zimmerli Introduction 21 Gram‐Positive Microorganisms 21 Gram‐Negative Microorganisms 26 Zoonotic Microorganisms 29 Anaerobic Microorganisms 34 Mycobacteria 35 Other Microorganisms 38 Key Points 40 References 40 Chapter 4 Identification of Pathogens in Bone and Joint Infections by Non‐Culture Techniques 51Maria Eugenia Portillo and Stephane Corvec Introduction 51 Broad‐Range PCR 51 Targeted PCR 53 Multiplex PCR 54 Next‐Generation Sequencing Approach 55 Mass Spectrometry‐Based Methods 58 Key Points 61 References 61 Chapter 5 Bacteriophages for Treatment of Biofilm Infections 65Mercedes Gonzalez‐Moreno, Paula Morovic, Tamta Tkhilaishvili, and Andrej Trampuz History of Bacteriophage Use in Human Infections 65 Principles of Bacteriophage Therapy 66 Activity of Bacteriophages against Bacterial Biofilms and Persisters 69 Bacteriophage Susceptibility Testing: the Phagogram 71 Experimental and Clinical Evidence with Bacteriophage Treatment 72 Local Delivery and Systemic Bacteriophage Application 74 Outlook and Future Perspectives 76 Key Points 77 References 78 Chapter 6 Pharmacokinetics and Pharmacodynamics of Antibiotics in Bone 81Cornelia B. Landersdorfer, Jurgen B. Bulitta, Roger L. Nation, and Fritz Sorgel Pharmacokinetics 81 Bone Sample Preparation and Analysis 82 Pharmacokinetic Sampling and Data Analysis 83 Penetration of Antibiotics into Bone 84 Pharmacodynamics and Monte Carlo Simulations 93 Conclusions 95 Key Points 96 References 96 Chapter 7 Preclinical Models of Infection in Bone and Joint Surgery 99Caroline Constant, Lorenzo Calabro, Willem‐Jan Metsemakers, R. Geoff Richards, and T. Fintan Moriarty Introduction 99 Influence of Species in Preclinical Models of Bone and Joint Infection 100 Overview of Animal Models 103 Direct Inoculation with Minimal Trauma 103 Animal Models of Bone and Joint Infection Incorporating Trauma 108 Hematogenous Models 108 Future Directions 109 Conclusions 110 Key Points 110 References 110 Chapter 8 Native Joint Arthritis in Children 117Pablo Yagupsky Introduction 117 Epidemiology 117 Microbiology 118 Pathogenesis 122 Clinical Presentation 123 Laboratory Investigation 125 Imaging Studies 127 Differential Diagnosis 128 Treatment 128 Prognosis 133 Key Points 134 References 134 Chapter 9 Native Joint Arthritis in Adults 139Florian B. Imhoff, David E. Bauer, and Ilker Uckay Introduction 139 Risk Factors 139 Pathogenesis, Epidemiology, and Microbiology 140 Diagnosis 141 Treatment 144 Outcome 147 Key Points 148 Acknowledgments 148 References 148 Chapter 10 Septic Arthritis of Axial Joints 151Werner Zimmerli Septic Arthritis of the Sternoclavicular Joint 151 Key Points 157 Septic Arthritis of the Symphysis Pubis 157 Key Points 161 Septic Arthritis of the Sacroiliac Joint 161 Key Points 165 References 165 Chapter 11 Periprosthetic Joint Infection: General Aspects 171Werner Zimmerli Introduction 171 Definition 172 Classification 172 Pathogenesis 172 Laboratory Investigation 176 Therapeutic Management 178 Prophylaxis 179 Errors in the Management of PJI 180 Key Points 180 References 181 Chapter 12 Periprosthetic Joint Infection after Total Hip and Knee Arthroplasty 187Werner Zimmerli, Rihard Trebse, and Martin Clauss Introduction 187 Risk Factors 188 Microbiology 188 Clinical Features 189 Laboratory Investigation 190 Imaging Procedures 191 Management 192 Instructive Cases 202 References 206 Chapter 13 Periprosthetic Joint Infection after Shoulder Arthroplasty 213Parham Sendi, Andreas Marc Muller, Beat K. Moor, and Matthias A. Zumstein Introduction 213 Risk Factors 213 Microbiology 215 Pathogenesis 216 Clinical Features 217 Laboratory Investigation 218 Imaging Procedures 220 Management 220 Instructive Cases 224 References 226 Chapter 14 Periprosthetic Joint Infection after Elbow Arthroplasty 231Yvonne Achermann, Michael C. Glanzmann, and Christoph Spormann Introduction 231 Microbiology 232 Clinical Features 232 Diagnostic Procedures 234 Management 237 Instructive Cases 242 References 245 Chapter 15 Periprosthetic Joint Infection after Ankle Arthroplasty 251Parham Sendi, Bernhard Kessler, and Markus Knupp Introduction 251 Risk Factors 252 Microbiology 254 Clinical Features 254 Laboratory Investigation 255 Imaging Procedures 256 Management 257 Instructive Cases 260 References 262 Chapter 16 Osteomyelitis: Classification 265Werner Zimmerli Classification According to Pathogenesis 265 Classification According to the Duration of Infection 267 Classification According to the Localization 268 Classification According to the Presence of an Implant 269 Classification According to Anatomy and Comorbidity 269 References 270 Chapter 17 Osteomyelitis in Children 273Alexander Aarvold, Priya Sukhtankar, and Saul N. Faust Introduction 273 Epidemiology 273 Pathophysiology 274 Clinical Presentation, Diagnosis, and Microbiology 275 Treatment 282 Complications 284 Key Points 285 References 286 Chapter 18 Acute Osteomyelitis in Adults 289Werner Zimmerli Introduction 289 Pathogenesis 289 Epidemiology 290 Microbiology 291 Risk Factors 293 Clinical Features 295 Laboratory Investigation 296 Imaging Procedures 298 Clinical and Imaging Differential Diagnosis 300 Treatment 301 Key Points 304 References 304 Chapter 19 Subacute Osteomyelitis: Tuberculous and Brucellar Vertebral Osteomyelitis 309Juan D. Colmenero and Pilar Morata Introduction 309 Epidemiology 309 Clinical Features 310 Laboratory Investigation 312 Imaging Procedures 315 Antimicrobial and Surgical Therapy 318 Key Points 321 References 321 Chapter 20 Chronic Osteomyelitis in Adults 325Felix W.A. Waibel, Benedikt Jochum, and Ilker Uckay Introduction 325 Pathogenesis 326 Diagnosis 326 Treatment 328 Key Points 333 Acknowledgments 333 References 333 Chapter 21 Diabetic Foot Osteomyelitis 337Eric Senneville and Olivier Robineau Introduction 337 Classification 337 Microbiology 339 Risk Factors 341 Clinical Features 342 Inflammatory Parameters 342 Imaging Procedures 343 Treatment 344 Prevention 347 References 348 Chapter 22 Osteomyelitis of the Jaws 353Werner Zimmerli Introduction 353 Classification 353 Microbiology 355 Risk Factors 356 Clinical Features 356 Laboratory Investigation 359 Imaging Procedures 360 Management 361 Key Points 363 References 364 Chapter 23 Fracture‐Related Infection of the Long Bones 367Parham Sendi, Mario Morgenstern, Willem‐Jan Metsemakers, and Martin McNally Introduction 367 Classification and Risk Factors 368 Microbiology 370 Clinical Features 371 Laboratory Investigation 372 Imaging Procedures 373 Management 373 Instructive Cases 380 References 383 Chapter 24 Implant‐Associated Vertebral Osteomyelitis 387Todd J. Kowalski and Arick P. Sabin Introduction 387 Classification and Risk Factors 388 Microbiology 389 Clinical Features 393 Diagnostic Procedures 393 Treatment 395 Instructive Cases 402 References 404 Chapter 25 Postoperative Sternal Osteomyelitis 409Parham Sendi, Mihai Constantinescu, and Lars Englberger Introduction 409 Risk Factors 410 Microbiology 414 Clinical Features 414 Laboratory Investigation 415 Imaging Procedures 417 Management 417 Instructive Cases 422 References 425 Index 429

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Book SynopsisPublisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.A comprehensive full-color guide to orthopedics in the primary care settingEspecially written for the primary care provider, Practical Office Orthopedics delivers outstanding full-color drawings, state-of-the-art radiographs, and a step-by-step approach to the evaluation and management of common bone and musculoskeletal complaints.This unique text is authored by Dr. Edward (Ted) Parks, whose practical orthopedics workshops at the regional and national American College of Physicians conferences have received top ratings from primary care providers of everyTable of ContentsChapter 1: The Kneea. Anatomy/Physiology basicsb. Ligament injuriesi) Historyii) Physical Examiii) Imagingiv) Treatment c. Meniscus Injuries i) Historyii) Physical Examiii) Imagingiv) Treatment d. Arthritis i) Historyii) Physical Examiii) Imagingiv) Treatment e. Problems of the Patellofemoral Joint i) Historyii) Physical Examiii) Imagingiv) Treatment f. “Diagnosis Unknown:” What to do with the knee that is none of the above Chapter 2: The Shouldera. Anatomy/Physiology basics b. Subacromial Space Impingement i) History ii) Physical Exam iii) Imaging iv) Treatment c. Glenohumeral Joint Arthritis i) History ii) Physical Exam iii) Imaging iv) Treatment d. Glenohumeral Joint instability i) History ii) Physical Exam iii) Imaging iv) Treatment e. AC Joint Instablitiy i) History ii) Physical Exam iii) Imaging iv) Treatment f. AC Joint Arthritis i) History ii) Physical Exam iii) Imaging iv) Treatment Chapter 3: The Hip a. Anatomy and Physiology basics b. Arthritis i) History ii) Physical Exam iii) Imaging iv) Treatment (including sidebar on famous flops) c. Bursitis i) History ii) PE iii) Imaging iv) Rx d. Pain referred to the hip from the lumbar spine i) Hx ii) PE iii) imaging iv) Rx e. Avascular Necrosis (AVN) i) Hx ii) PE iii) Imaging iv) Rx f. Femoral/Acetabular Impingement & Labral tears i) Hx ii) PE iii) Imaging iv) Rx g. Hip fractures i) anatomy ii) classification iii) imaging iv) treatment Chapter 4: Hand/Wrist/Elbow a. carpal tunnel (dead guy cartilage/fingernail story sidebar here?) & nbsp; “ b. trigger finger “ c. lateral/medial epicondylitis “ d. Cubital tunnel syndrome “ e. DeQuervaine’s Syndrome “ f. thumb basal joint OA (1st CMC OA) “ g. skiier’s/gamekeeper’s thumb Chapter 5: Foot/Ankle a. anatomy/physiology basics b. Morton’s neuroma c. plantar fasciitis d. Achillies tendonitis e. bunions and hammertoes f. Ankle sprains and fractures Chapter 6: Spine a. anatomy/physiology basics b. low back pain i)with radiculopathy ii)without radiculopathy c. Spinal stenosis d. Vertebral compression fxs Chapter 7: Orthopedic Emergencies a. compartment syndrome b. Ortho injuries with neurovascular compromise c. Septic arthritis d. open fxs e. extremity amputation f. spinal cord injuriesChapter 8: Principles of fracture management Chapter 9: Miscellaneous Tips and Tricks

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Book SynopsisSystemic and nervous system vasculitides are a heterogeneous group of related disorders, each characterized by vascular inflammation such that they have the potential to cause serious morbidity and mortality if unrecognized and therefore untreated. Systemic vasculitis affect all populations and every nationality and walk-of-life, from childhood to older age. The first edition of The Vasculitides, published in 2014, met the urgent need for a clear, concise, and reliable textbook regarding the epidemiology, pathogenesis, clinical presentation, laboratory evaluation and management of these disorders, assembling participants of the 16th International Vasculitis and ANCA Workshop in Paris, France. Five years later, two subsequent meetings have taken place in London and Tokyo. Participants of the 19th International Vasculitis & ANCA Workshop will gather in April 2019 at the University of Pennsylvania for an exceptional venue to share translational scientific discoveries, data from clinical trials, and advances in the clinical assessment, pathophysiology, genetic biomarkers, standard-of-care, and novel therapies of vasculitis. The Workshop participants regathered to update the The Vasculitides, producing an even more cutting-edge two-volume set of books. This is the first book in the set, covering general considerations and systemic vasculitis.

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Book SynopsisSystemic and nervous system vasculitides are a heterogeneous group of related disorders, each characterized by vascular inflammation such that they have the potential to cause serious morbidity and mortality if unrecognized and therefore untreated. Systemic vasculitis affect all populations and every nationality and walk-of-life, from childhood to older age. The first edition of The Vasculitides, published in 2014, met the urgent need for a clear, concise, and reliable textbook regarding the epidemiology, pathogenesis, clinical presentation, laboratory evaluation and management of these disorders, assembling participants of the 16th International Vasculitis and ANCA Workshop in Paris, France. Five years later, two subsequent meetings have taken place in London and Tokyo. Participants of the 19th International Vasculitis & ANCA Workshop will gather in April 2019 at the University of Pennsylvania for an exceptional venue to share translational scientific discoveries, data from clinical trials, and advances in the clinical assessment, pathophysiology, genetic biomarkers, standard-of-care, and novel therapies of vasculitis. The Workshop participants regathered to update the The Vasculitides, producing an even more cutting-edge two-volume set of books. This is the second book in the set, covering vasculitis of the nervous system and treatments.

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Book SynopsisA comprehensive and fully illustrated guide for the diagnosis and initial management of rheumatic disorders Topics include: - Physical examinations and approaches to common rheumatic presentations - How to select and interpret laboratory tests and imaging - How to handle specific rheumatologic emergencies - Joint aspiration and injection techniques Residents in rheumatology, internal medicine and family medicine programs, practicing physicians and medical students will find this handy pocket guide to be an indispensable resource. Allied health professionals and nurse practitioners will also find it accessible and informative, helping them to better manage their patients and clients.

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Book SynopsisArthritis is an inflammatory disease affecting the joints and surrounding tissues. As the disease develops it can cause severe pain and disability. The two most common types of arthritis are osteoarthritis and rheumatoid arthritis. Osteoarthritis (OA) is a painful, degenerative joint disease that often involves the hips, knees, neck, lower back, or the small joints of the hands. Treatment usually includes analgesics, topical creams, or non-steroidal anti-inflammatory medications (known as NSAIDs); appropriate exercises or physical therapy; joint splinting; or joint replacement surgery for seriously damaged larger joints, such as the knee or hip. Rheumatoid arthritis (RA) is an auto-immune inflammatory disease that usually involves the hands, wrists, elbows, shoulders, knees, feet, or ankles. This book brings together leading research in the field.

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Book SynopsisThe aim of this book is to be a guide to general practitioners and paediatricians under the light of the current concepts. It will not only help the reader to understand the pathogenesis of common childhood rheumatic diseases, but also provide the general practitioners with a current algorithm that will help them to decide what to do and when to seek reference. It is the child with arthritis, recurrent fever, or a non-specific rash that is a diagnostic dilemma, and that is waiting for someone to solve the problem. For this reason, this book includes real case histories with their photos, radiographic findings, and further investigations, where necessary.

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Book SynopsisFibromyalgia syndrome is a common and chronic disorder characterised by widespread muscle pain, fatigue, and multiple tender points. The word fibromyalgia comes from the Latin term for fibrous tissue (fibro) and the Greek ones for muscle (myo) and pain (algia). Tender points are specific places on the body -- on the neck, shoulders, back, hips, and upper and lower extremities -- where people with fibromyalgia feel pain in response to slight pressure. Although fibromyalgia is often considered an arthritis-related condition, it is not truly a form of arthritis (a disease of the joints) because it does not cause inflammation or damage to the joints, muscles, or other tissues. Like arthritis, however, fibromyalgia can cause significant pain and fatigue, and it can interfere with a person''s ability to carry on daily activities. Also like arthritis, fibromyalgia is considered a rheumatic condition. This book presents the latest research in this field.

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Book SynopsisFibromyalgia syndrome is a common and chronic disorder characterised by widespread muscle pain, fatigue, and multiple tender points. The word fibromyalgia comes from the Latin term for fibrous tissue (fibro) and the Greek ones for muscle (myo) and pain (algia). Tender points are specific places on the body -- on the neck, shoulders, back, hips, and upper and lower extremities -- where people with fibromyalgia feel pain in response to slight pressure. Although fibromyalgia is often considered an arthritis-related condition, it is not truly a form of arthritis (a disease of the joints) because it does not cause inflammation or damage to the joints, muscles, or other tissues. Like arthritis, however, fibromyalgia can cause significant pain and fatigue, and it can interfere with a person''s ability to carry on daily activities. Also like arthritis, fibromyalgia is considered a rheumatic condition. This new book presents the latest research in this field.

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Book SynopsisHand radiography is usually the first step in the evaluation of arthritis. With hundreds of high-quality images, this work provides a simplified but high-quality diagnostic interpretation of hand radiography, for residents in training and experienced physicians, who wish to improve their knowledge of contemporary rheumatology, according to the rapid progress of treatment using biologic agents and various new diagnostics tools, including MRI and ultrasound. Topics discussed include arthritis in Behcet''s disease; adult onset Still''s disease; osteonecrosis in lupus; seronegative spondyloarthropathies; gout; and systemic sclerosis.

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Book SynopsisFor eight decades the Primer on the Rheumatic Diseases has been the standard text from which most medical students and house ofcers have learned rheumatology. I myself will never forget thumbing through an older edition of the Primer as a second-year resident, while waiting to review a perplexing patient with my tutor. Fortunately the tutor was r- ning late with his own patients, so I had time to fip through the book – then much thinner – a couple of times. While turning the pages, per- ing the features of those diseases whose names were still exotic to me, and considering my patient’s history of conductive hearing loss and p- monary nodules, a light went on when I stumbled eventually on a part- ular chapter. I still remember the jaw-dropping efect on my tutor of my announcement then that I had a patient with Wegener’s granulomatosis. I think I became a rheumatologist that very moment! Subsequent editions of the Primer have sufered from the inevitable “obesity creep,” making it an outstanding reference textbook but virtually impossible to fip through quickly while awaiting one’s tutor, and even more difcult to slip into the pocket of a white coat to carry on rounds. For this reason we have created the Pocket Primer, a mini version that cuts the larger book down to its essentials.Table of ContentsHistory and Physical Examination.- Laboratory Assessment.- Arthrocentesis and Synovial Fluid Analysis.- Imaging Techniques.- Monarticular Joint Disease.- Polyarticular Joint Disease.- Regional Rheumatic Pain Syndromes.- Fibromyalgia and Diffuse Pain Syndromes.- Rheumatoid Arthritis.- Juvenile Idiopathic Arthritis.- Psoriatic Arthritis.- Ankylosing Spondylitis.- Reactive and Enteropathic Arthritis.- Osteoarthritis.- Calcium Pyrophosphate Dihydrate, Hydroxyapatite, and Miscellaneous Crystals.- Infectious Disorders.- Systemic Lupus Erythematosus.- Antiphospholipid Syndrome.- Systemic Sclerosis.- Idiopathic Inflammatory Myopathies.- Metabolic Myopathies.- Sjögren’s Syndrome.- Vasculitides.- Behçet’s Syndrome.- Adult Still’s Disease.- Autoinflammatory Disorders/Periodic Syndromes.- Less Common Arthropathies.- Complex Regional Pain Syndrome.- Osteonecrosis.- Paget’S Disease.- Osteoporosis.- Therapeutic Injections.- Nonsteroidal Anti-Inflammatory Drugs.- Glucocorticoids.- Operative Treatment.- Complementary and Alternative Therapies.

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Book SynopsisThe book summarizes recent advances in the elucidation of the mechanisms involved in senile osteoporosis as well as its potential treatment, bringing an integrated approach from the bench to the clinical practice. A unique aspect of this book is its emphasis on the application of translational research in the field of osteoporosis and falls. The book provides a complete review on the prevention as well as current and future treatments of osteoporosis.Trade ReviewFrom the reviews: "The authors of this multiauthored book bring together new information on the molecular biology of bone physiology in this examination of osteoporosis in older persons. … The intended audience includes all health practitioners who treat older patients with osteoporosis. Research scientists in the area will find this book useful as well. … This book’s demonstration of the complex relationship of bone health to adipose tissue and several powerful hormones will stimulate new thinking in the area of osteoporosis." (David O. Staats, Doody’s Review Service, August, 2008) "This is a simply outstanding compilation that provides a clear and concise review of the effect age has on the skeleton at the molecular/genetic level, in animal models as well as humans. … It provides clinicians with an overview of cellular mechanisms leading to bone loss and researchers with insight into the clinical consequences of age-related skeletal change in older adults. That such a text has not previously been written and become a reference standard among clinicians, geriatricians, and researchers … ." (Neil Binkley, JAMA, Vol. 300 (11), September, 2008)Table of ContentsBiology of Bone.- Aging and Bone.- Calciotropic Hormones.- Sex Steroids and Aging Bone.- Animal Models for Senile Osteoporosis.- Senile Osteoporosis as a Geriatric Syndrome.- Genetics of Osteoporosis in Older Age.- Fracture Epidemiology Among Individuals 75+.- Falls as a Geriatric Syndrome: How to Prevent Them? How to Treat Them?.- Non-Pharmacological Treatments for Falls and Fractures.- Medical Treatment of Age-Related Osteoporosis: Present and Future.- Treatment of Osteoporosis in Long-Term Care.- Fracture Care in the Elderly.

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Book SynopsisThis exciting book reflects the multidisciplinary approach that has proved so beneficial to the care of the rheumatology patient. Written by well qualified members of the various professions involved in this field, the book examines the full range of treatment and care of the patient. This book will prove invaluable to nurses, occupational therapists, podiatrists, physiotherapists, social workers and dieticians.Table of ContentsContributors vii Preface ix Chapter 1 1 Chapter 2 12 Chapter 3 46 Chapter 4 68 Chapter 5 98 Chapter 6 143 Chapter 7 186 Chapter 8 223 Chapter 9 244 Chapter 10 257 Chapter 11 272 Chapter 12 290 Index 321

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Book SynopsisBack pain is the commonest form of rheumatism and it is estimated to affect between 65% and 80% of populations sampled. The costs of back pain-related medical care and disability compensation make it one of society's most significant non-lethal medical conditions. Whilst mortality is low, its morbidity is high, inconvenience great, and economic burden massive. The actual symptom of back pain is one of the commonest and most perplexing encountered in medical practice. A proper understanding of what it means is crucial for further medical advance. However, the field of back pain research probably has more experts than any other. Anybody who has back pain will, as often as not, expound views on all matters concerning causation and expectations. Indeed, it is not for a lack of ideas that this field of investigation has failed to make progress. A respected senior investigator advised me early on that patients could not even tell which side their pain was on. It was only many years later that I discovered why. Though the initial incident or accident would seem important to the patient and to the researcher, it is remarkable how little it helps distinguish patterns of back pain. Tests of inappropriate behaviour in the past have been widely disseminated and yet even the originators have said that they cannot be sure of the implications of positive non-organic test findings. This book will show that these 'indicators' are not what they seem to be. In many cases, it is difficult to tell which level in the lumbar spine the pain comes from, and thus treatments such as injections or operation, may be given at the wrong level, let alone the wrong side. Though the various forms of back pain treatment seem to help some patients, when these same treatments are subjected to randomised controlled trials, the evidence for efficacy seems to all but vanish. With all these difficulties and uncertainties, it can be seen why low back pain presents one of the most fallible fields of healthcare. This book indicates that there are ways of dealing with the majority of these problems. Many of the answers from the research conducted were most unexpected. The reader is also advised that the scientific approach cannot deliver hard and fast answers to all contemporary questions in such a wide field and much has depended on the choice of problems to study. Whilst the tests used to distinguish the patterns in this study have their limitations, and whilst there is, as yet, only limited evidence as to the underlying pathology for the patterns recognised, it is felt that some of the other patterns identified are descriptive of diagnoses that are generally accepted. If the answers that are put forward appear to change the direction of understanding, it is hoped that you, the reader, will be able to carry the enquiry further when you see patients, advise treatment or even experience back pain yourself!

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Book SynopsisMusculoskeletal Pain - Assessment, Prediction and Treatment presents a common sense approach to interpreting and applying existing clinical knowledge and new research to help clinicians make sense of the complex phenomena of acute and chronic post-traumatic musculoskeletal pain. Built upon the Assess, Predict, Treat framework, the authors offer a method to help clinicians better understand their patients'' pain. They present evidence-based decision tools to predict the natural and clinical course of common conditions, such as neck and low back pain, and they then synthesize that information into a logical, integrated treatment approach, which respects the individuality of the patient, the experiences of the clinician, and the value of evidence-informed practice.David Walton and James Elliott are leaders in the field of post-traumatic pain and recovery. Their work provides a valuable framework to facilitate novice clinicians in their transition towards experts and helps mid- and late-stage clinicians better interpret, synthesize, and discuss complex information on pain with the goal of optimised outcomes for patients.

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Book SynopsisDesigned as reference material to increase knowledge of the human body. Beautiful full-colour illustrations help enhance understanding of the body or illness. Suitable for healthcare professions, patients, students, educators and parents.

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Book SynopsisDesigned as reference material to increase knowledge of the human body. Beautiful full-colour illustrations help enhance understanding of the body or illness. Suitable for healthcare professions, patients, students, educators and parents.

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Book SynopsisThis practical guide aids clinicians in distinguishing the different dimensions of hand function such as impairment, disability, and handicap. New and updated chapters discuss cerebral palsy, sports injuries, robotics, and assistive technologies. Extensively revised, the book provides a broad overview of the basic principles and examination of hand function. It describes how to evaluate hand function in specific afflicted populations, including the rheumatoid patient, the stroke patient, the trauma patient, the geriatric patient, and the pediatric patient as well as special populations such as diabetes mellitus patients and musicians. It also includes an appendix of hand function scales essential to the assessment of disability. The Second Edition of Hand Function is an ideal resource for all rheumatologists, physiatrists, hand surgeons, orthopedists, occupational therapists, and physical therapists caring for patients with impaired hand function.Table of ContentsSECTION I: Basic Principles of Hand Function.- Functional Anatomy and Biomechanics of the Hand.- Physical Examination of the Hand.- Assessment of Hand Functions.- SECTION II: Hand Function in Clinical Practice.- Pain and Hand Function.- Hand Function in Rheumatoid Arthritis.- Hand Function in Osteoarthritis.- Hand Function in Scleroderma.- Functional Assessment in Hand with Flexor and Extensor Tendon Injuries.- Hand Function in Stroke.- Hand Function in Tetraplegia.- Hand Function in Parkinson’s Disease.- Hand Function in Cerebral Palsy.- Hand Function in Children with Congenital Disorders.- Hand Function in Juvenile Idiopathic Arthritis.- Functional Assessment in Geriatric Conditions.- Hand Function in Common Hand Problems.- Hand Function in Sport Injuries.- Hand Function in Metabolic Disorders: Haemodialysis, Diabetes Mellitus, Gout.- SECTION III: Hand Function with Robotics and Assistive Technology.- Hand Function and Assistive Devices.- Sports and Recreational Adaptations for Hand.- The Functional Capacity of the Robotic Hands.- SECTION IV: Hand Function and Imaging Outcomes.- Hand Function and Imaging Outcomes.- Appendix: Some Hand Functional Scales

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Book SynopsisThis book provides a concise and up-to-date review of key rheumatology topics along with extensive practice questions to assist in preparing for the American Board of Internal Medicine (ABIM) Rheumatology Certification Exam.Each chapter focuses on a single disease and starts with a short review (primarily tables and figures) to highlight the main points and key issues. The review is followed by 10-20 board-style multiple choice questions with detailed explanations for each topic. The chapters and associated preparation questions are written by established experts from top institutions in the United States. The book concludes with a 50-question practice test reflecting the format used by the ABIM Board Certification Exam.Absolute Rheumatology Review is an essential resource for not only graduate students, residents, and fellows in rheumatology and internal medicine studying for board exams but also rheumatologists, physicians, and related professionals preparing for recertification.Table of ContentsIntroduction.-Immunological Basis of Inflammatory Arthritides.-Clinical Epidemiology for Rheumatologists.-Osteoarthritis.-Regional Musculoskeletal Syndromes and the use of MSK Ultrasound.-Infectious Arthritis.-Rheumatoid Arthritis.-Psoriatic Arthritis.-Axial Spondyloarthritis.-Systemic Lupus Erythematosus.-Sjogren's Syndrome.-Systemic Sclerosis (Scleroderma).-Vasculitis.-Inflammatory Myopathies.-Osteoporosis.-Crystal Arthritis.-Autoinflammatory Diseases.-Pediatric Rheumatology for Adult Rheumatologists.-Musculoskeletal Manifestations of Systemic Diseases.-Clinical Genetics in Rheumatology

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Book SynopsisWith the increasing use of immune checkpoint inhibitors (ICI) across various cancers, the trends for indication at earlier stages, and the use of combination immunotherapy, the frequency of ICI-induced immune-related adverse events (irAE) is expected to grow substantially. Management of these irAE is challenging as it requires not only consideration of the toxicity but also risk-benefit ratios with respect to the primary cancer. Several rheumatic irAE have been reported with ICI therapy including arthritis, myositis, polymyalgia-like syndromes, sicca/Sjogren-like manifestations, and several other less common systemic autoimmune features commonly associated with connective tissue disease. This handbook provides clinicians with a comprehensive overview of the management of rheumatic irAE that develop from cancer immunotherapy. It focuses on the irAE seen with ICI, the most frequently used agents in treating cancer. It provides an overview of cancer immunology, immunotoxicity, and immunotherapies such as ICI, cytokine-based therapy, and CART. It examines the epidemiology, clinical manifestations, diagnosis, differential diagnosis, and treatment of a variety of rheumatic immune-related adverse events arising from these therapies. Chapters also cover cancer immunotherapy in patients with preexisting rheumatic diseases such as inflammatory arthritis and other connective tissue disorders. The book helps clinicians to distinguish the current types of cancer immunotherapy and general toxicity patterns, recognize and diagnose rheumatic clinical syndromes, understand the pathogenesis of irAE, and consider risk–benefit ratios when managing patients with rheumatic irAE.Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy is an essential resource for physicians and related professionals, residents, fellows, graduate students and nurses alike in rheumatology, clinical immunology, oncology, and internal medicine.Table of ContentsPART 1 - INTRODUCTION1. Cancer Immunology and the evolution of immunotherapy 2. Cancer immunotherapy: overview 3. Pathogenesis of immune-related adverse eventsPART 2 – IMMUNE-RELATED ADVERSE EVENTS WITH IMMUNE-CHECKPOINT INHIBITORS4. Arthritis 5. Polymyalgia rheumatica6. Myositis7. Sicca syndromes 8. Sarcoidosis 9. Miscellaneous rheumatic syndromes 10. Non-rheumatic immune-related adverse events11. Immune-related adverse events with other cancerimmunotherapiesPART 3 – CANCER IMMUNOTHERAPY IN PATIENTS WITH PRE-EXISTING RHEUMATIC DISEASES12. Inflammatory arthritis13. Other rheumatic autoimmune diseases14. Choosing the right therapy15. Risk-benefit considerations16. Patient education and shared-decision making

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Book SynopsisThis book answers questions about the critical role of ultrasound in the management of patients with Sjögren’s syndrome. It also covers developments rheumatologists can foresee in performing a biopsy of the parotid gland. Each chapter is authored by experts on this condition, emphasizing the extent of current understanding and dealing with unanswered challenges and pitfalls. Topics such as modern imaging techniques like ultrasound and MRI and their importance are given particular focus in this book; practitioners are increasingly using imaging techniques to refine diagnosis and guide clinical management. Additionally, as a significant emerging point of interest in the field, biopsy of the major salivary glands, particularly ultrasound-guided procedures, receives extra attention within the text. The book also includes a chapter that deals with future directions and will also review the challenges patients face with unmanaged Sjögren’s syndrome. Comprehensive and concise, Sjögren’s Syndrome and the Salivary Glands provides a balanced overview between the chapters and ensure homogeneity of the terminology. Table of ContentsCh 1. Introduction Ch 2. Epidemiology Ch 3. Pathogenesis of Sjögren’s syndrome Ch 4. Anatomy of the major salivary glands Ch 5. Imaging of Sjögren’s syndrome Ch 6. Sonoanatomy of the major salivary glandsCh 7. Ultrasound of Sjögren’s syndromeCh 8. MRI in the management of Sjögren’s syndromeCh 9. Biopsy of the minor salivary glandsCh 10 Biopsy of the major salivary glandsCh 11.Pitfalls and future directions

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Book SynopsisThis book details the practice of telerheumatology. Telemedicine is defined as the delivery of healthcare and the exchange of healthcare information across distances. Following, telerheumatology is the delivery of rheumatology care through telemedicine. There exists an increasing demand from patients, caregivers, and healthcare systems for access to academic specialists through telemedicine. This has been the case for the past several years and the demand has only increased with the ongoing COVID-19 pandemic. There is currently a lack of rheumatologists in rural areas and that is expected to spread to a general lack by 2025. Telerheumatology offers an excellent and timely solution to fill these gaps and provide care.Telerheumatology care has been shown to be feasible and quite effective. The current COVID-19 pandemic has thrust the concept of telemedicine into the spotlight. However, not all telerheumatology care is the same and there exists many nuances and differences when examining telerheumatology care across the United States and the world. After comprehensively reviewing the origins of telerheumatology, this work defines in detail the current practice of telerheumatology, along with the specific impact of the COVID-19 pandemic and all applications of telerheumatology. Expert authors also provide a detailed roadmap for providers to initiate, sustain, and grow a telerheumatology program. The book concludes by covering future directions of telerheumatology, including areas for expansion, improvement, and innovation.After reading this work, the editor and all the contributing authors hope that it will inspire, provoke thought and discussion, and lead to increased adaptation of providing telerheumatology care by rheumatologists and rheumatology providers.Table of Contents

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Book SynopsisThis book builds upon the first edition with new and improved chapters. The book explores the rich assemblage of clinical wisdom from expert rheumatologists from a wide range of specialties including Vasculitis and Sjogren’s syndrome. It examines the nuggets or ‘pearls’ of wisdom gained from collective clinical experience about the diagnosis or treatment of various diseases whilst also aiming to debunk myths that have influenced the practice of rheumatology by many clinicians. The second edition of A Clinician's Pearls and Myths in Rheumatology is a critical resource for both practitioners and students of rheumatology. This book provides a clear guide for those wishing to take a “deep dive” into the diagnostic and therapeutic elements of rheumatology. Table of ContentsRheumatoid Arthritis.- Rheumatoid Vasculitis.- Adult-Onset Still's Disease.- Juvenile Idiopathic Arthritis.- Monogenic Autoinflammatory Syndromes.- Juvenile Spondyloarthropathy.- Ankylosing Spondylitis.- Psoriatic Arthritis.- Reactive Arthritis.- Systemic Sclerosis (Scleroderma) and Raynaud’s Phenomenon.- Nephrogenic Systemic Fibrosis and Other Scleroderma Mimickers.- Sjögren's Syndrome.- Systemic Lupus Erythematosus.- Pediatric Systemic Lupus Erythematosus.- Mixed Connective Tissue Disease.- The Antiphospholipid Syndrome.- Pregnancy in the Rheumatic Diseases.- Inflammatory Myopathies.- Juvenile Dermatomyositis.- Vasculitic Neuropathy.- Pediatric Vasculitis.- Behçet's Syndrome.- The Churg—Strauss Syndrome.- ANCA-Associated Vasculitis.- Cryoglobulinemia.- Polyarteritis Nodosa.- Giant Cell Arteritis and Polymyalgia Rheumatica.- Takayasu's Arteritis.- Primary Angiitis of the Central Nervous System and Reversible Cerebral Vasoconstriction Syndromes.- Thromboangiitis Obliterans (Buerger's Disease).- Less Common Forms of Vasculitis.- Relapsing Polychondritis.- Fibromyalgia.- The Clinical Features of Gout.- Gout Epidemiology.- Gout Treatment.- Calcium Pyrophosphate Dihydrate (CPPD) Crystal Deposition Disease.- Inflammatory Eye Disease.- Immune-Mediated Inner Ear Disease.- Osteoporosis.- Paget's Disease of Bone.- Sarcoidosis.- Osteoarthritis.- Regional Musculoskeletal Complaints.- Low Back and Neck Pain.- Amyloidosis.- The Ehlers—Danlos Syndrome.- Osteonecrosis.

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Book SynopsisThis book comprehensively reviews clinical aspects and features of rheumatic and musculo-skeletal diseases in an integrated and easy to read format. It enables the reader to become confident in identifying common and unusual disease symptoms and be able to apply a variety of diagnostic modalities and evaluate potential treatment options. Every disease covered has a variety of clinically relevant images detailing both typical and rare signs and symptoms. Each image is accompanied by a detailed description covering relevant epidemiological data, diagnostic modalities and treatment options. The Illustrated Handbook of Rheumatic and Musculo-Skeletal Diseases, 2ndEdition has been fully revised with new content and clinical photographs throughout each chapter. Rheumatologists seeking a comprehensive and clinically relevant guide for the diagnosis and treatment of a broad range of rheumatic and allied diseases will find this book to be an essential resource in their daily clinical practice. Table of Contents1. Clinical Examination of the musculoskeletal system.- 2. Laboratory and immunological tests in Rheumatology.- 3. Rheumatoid Arthritis.- 4. Sjögren’s syndrome.- 5. Psoriatic Arthritis.- 6. Ankylosing Spondylitis.- 7. Systemic Lupus Erythematosus and antiphospholipid syndrome.- 8. Scleroderma.- 9. Inflammatory Myopathies.- 10. Vasculitides.- Osteoarthritis.- 11. Crystal arthropathies.- 12. Gout.- 13. Pseudogout (Calcium Pyrophosphate Dihydrate Crystal Deposition Disease).- 14. Hydroxyapatitie.- 15. Complex regional pain syndromes.- 16. Osteoporosis.- 17. Osteonecrosis.- 18. Miscellaneous conditions.- 19. Sarcoidosis.- 20. Relapsing polychondritis.- 21. DISH (Diffuse Idiopathic Skeletal Hyperostosis.- 22. Adverse drug reactions in Rheumatology.

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