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Book SynopsisThis text assesses the role of dendritic cells, T and B lymphocytes, epithelial and mast cells, eosinophils, neutrophils, macrophages, and their products in the initiation and progression of airway inflammation, regulation, and repair. It unveils advances in immunology and cell biology to generate new therapeutic regimens for inflammatory and allergic diseases,and offers unparalleled research from nearly 60 international contributors.Table of ContentsThe cells of the pulmonary immune response: overview of the pulmonary immune response, Laurent P. Nicod; antigen-presenting cells, Henk C. Hoogsteden, Hamida Hammad, and Bart N. Lambrecht; CD4 T lymphocytes in allergic asthma, Mark Larche and A.B. Kay; B-Cell differentiation and IgE synthesis, Hamida Hammad and Bart N. Lambrecht; immune functions of mast cells and basophils, Sarbjit S. Saini; immune functions of human eosinophils, Paul J. Coffer, Patricia M. R.E. Silva, Marco A. Martins, and Leo Koenderman; immune functions of airway epithelium, Sundeep S. Salvi and Stephen T. Holgate. Regulation processes in the pulmonary immune response: tolerance to inhaled antigen, Elizabeth R. Jarman, Gerard F. Hoyne and Jonathan R. Lamb; sensitization to inhaled allergen, Susan L. Prescott; polarization of T-helper cells, Martien L. Kapsenberg, Eddy A. Wierenga, Pawel Kalinski and Esther C. De Jong; CD28 and B7 superfamily members - costimulation and regulation of T-cell function, Anthony J. Coyle, Stephen Manning, and Jose-Carlos Gutierrez-Ramos; control of lymphocyte trafficking through the lung, Reinhard Pabst and Thomas Tschernig; neuroimmune interactions in the pathogenesis of allergic asthma, Armin Braun, Wolfgang A. Nockher, and Harald Renz. Integrated immunology of airway inflammation: immunopathology of atopic and nonatopic asthma, Marc Humbert, Sun Ying, and Douglas S. Robinson; immunology of eosinophilic airway inflammation - what the animal models teach us, Bart N. Lambrecht, Leonie S. Van Rijt, and Harmjan Kuipers; regulation of cellular traffic in the asthmatic lung, Clare M. Lloyd and Jose-Carlos Gutierrez-Ramos; cytokine regulation of bronchial hyperresponsiveness, Johan C. Kips and Romain A. Pauwels; immunological functions of inflammatory mediators, Domenico Spina, Clive Page, Anthony P. Sampson, and Zuzana Diamant; virally induced eosinophilic airway inflammation, Wieslawa Olszewska and Peter J.M. Openshaw; airway remodelling as the outcome of a chronic immu

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Book SynopsisMusculoskeletal Pain - Assessment, Prediction and Treatment presents a common sense approach to interpreting and applying existing clinical knowledge and new research to help clinicians make sense of the complex phenomena of acute and chronic post-traumatic musculoskeletal pain. Built upon the Assess, Predict, Treat framework, the authors offer a method to help clinicians better understand their patients'' pain. They present evidence-based decision tools to predict the natural and clinical course of common conditions, such as neck and low back pain, and they then synthesize that information into a logical, integrated treatment approach, which respects the individuality of the patient, the experiences of the clinician, and the value of evidence-informed practice.David Walton and James Elliott are leaders in the field of post-traumatic pain and recovery. Their work provides a valuable framework to facilitate novice clinicians in their transition towards experts and helps mid- and late-stage clinicians better interpret, synthesize, and discuss complex information on pain with the goal of optimised outcomes for patients.

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Book Synopsis

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Book Synopsis

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Book SynopsisDieser umfassende Überblick vermittelt Ihnen klinikbezogen das aktuelle Wissen zur allgemeinen und speziellen Pathologie der Gelenkerkrankungen und des Bindegewebes.Didaktisch klar, mit umfangreichem Abbildungsmaterial- Fundierte Darstellung der Pathogenese und Morphologie- Detaillierte Beschreibung der einzelnen Krankheiten- Mikroskopischer, makroskopischer und Röntgenbefund übersichtlich in synoptischen TableausEin Handbuch und Nachschlagewerk, das Ihnen praktische Entscheidungshilfen für die Befundinterpretation und Therapie liefert.Table of Contents1 Bausteine und Organisationsformen des Bindesgewebes.- 1.1 Zellen.- 1.1.1 Fibroblasten, Fibrozyten und Tendozyten.- 1.1.2 Myofibroblasten.- 1.1.3 Synoviozyten.- 1.1.4 Chondrozyten.- 1.1.5 Fibrochondrozyten.- 1.2 Matrix.- 1.2.1 Kollagen.- 1.2.2 Elastin.- 1.2.3 Proteoglykane.- 1.2.4 Adhäsive Glykoproteine.- 1.2.5 Integrine.- 1.2.6 Umsatz der Matrix.- 1.2.7 Degradative Enzyme.- 1.3 Organisationsformen.- 1.3.1 Gallertiges Bindegewebe.- 1.3.2 Lockeres Bindegewebe.- 1.3.3 Straffes Bindegewebe.- 1.3.4 Kompaktes Bindegewebe.- Literatur.- 2 Morphologie des organisierten Bindegewebes.- 2.1 Gelenke.- 2.1.1 Knorpel.- Hyaliner Knorpel.- Faserknorpel.- 2.1.2 Gelenkkapsel.- 2.1.3 Synovia.- 2.2 Spezielle Gelenke.- 2.3 Zwischenwirbelscheiben.- 2.4 Sehnen.- 2.4.1 Sehnen-Muskel-Insertionen.- 2.4.2 Sehnen-Knochen-Insertionen.- 2.5 Ligamente, Aponeurosen und Faszien.- 2.6 Bursen.- 2.7 Allgemeine Altersveränderungen.- Literatur.- 3 Reaktionsformen des organisierten Bindegewebes.- 3.1 Synovialmembran.- 3.1.1 Entzündungen.- Neurogene Entzündung.- Vaskulitiden.- Nekrosen.- Zelluläre entzündliche Infiltration.- Gesteigerte Zellproliferation.- Zellemigration durch die Deckzellschicht.- Entzündlicher Gelenkerguß.- Synoviale Ulzerationen.- Detritussynovialitis.- Fibrinexsudation.- Granulationsgewebe.- Narbengewebe.- Zottenbildung.- Zottenverwachsungen.- Vermehrung des synovialen Gewebes.- 3.1.2 Reparation synovialer Defekte.- 3.1.3 Synoviale Metaplasien.- 3.1.4 Pathologische Osteoneogenese.- 3.1.5 Fremdkörperreaktionen.- Fremdkörper und Infektionen.- Fremdkörper und Tumoren.- 3.2 Hyaliner Knorpel.- 3.2.1 Folgen der Immobilisation.- 3.2.2 Thermische Schädigungen.- 3.2.3 Mechanische Schädigungen.- Einmalige direkte Traumen.- Wiederholte minore Traumen.- 3.2.4 Zerstörung bei Entzündungen.- Zerstörung durch Bakterien, Enzyme und Zellen der Synovia.- Zerstörung durch veränderte Chondrozytenfunktion.- Zerstörung durch Pannusgewebe.- 3.2.5 Reparationsversuche nach Zerstörung.- 3.3 Faserknorpel.- 3.3.1 Folgen der Immobilisation.- 3.3.2 Mechanische Schädigungen.- 3.3.3 Zerstörung bei Entzündungen.- 3.3.4 Reparationsversuche nach Zerstörung.- 3.4 Entzündlicher Knochenumbau.- 3.5 Pathogenese von Gelenkschmerzen.- 3.6 Allgemeine morphologische Diagnostik.- 3.7 Erklärung einiger klinischer Bezeichnungen.- Literatur.- 4 Entwicklungsdefekte.- 4.1 Allgemeine Häufigkeit.- 4.2 Gelenkfehlbildungen.- 4.3 Hüftgelenkdysplasie.- 4.4 Protrusio acetabuli.- 4.5 Epiphyseolysis capitis femoris.- 4.6 Scheibenmeniskus.- 4.7 Plica-Krankheit des Kniegelenkes.- 4.8 Chondrodystrophien.- 4.8.1 Achondroplasie.- 4.8.2 Spondyloepiphysäre Dysplasien.- 4.9 Hereditäre Bindegewebskrankheiten.- 4.9.1 Marfan-Syndrom.- 4.9.2 Ehlers-Danlos-Syndrom.- 4.9.3 Osteogenesis imperfecta.- 4.10 Arthrogryposen.- 4.11 Werner-Syndrom.- Literatur.- 5 Endokrine Krankheiten.- 5.1 Diabetes mellitus.- 5.1.1 Diabetische Arthropathie.- 5.1.2 Diabetische Cheiroarthropathie.- 5.1.3 Idiopathische diabetische Muskelinfarkte.- 5.2 Hyperparathyroidisms.- 5.3 Hypothyreose.- 5.4 Akromegalie.- 5.5 Karzinoid-Syndrom.- Literatur.- 6 Stoffwechselkrankheiten.- 6.1 Gaucher-Krankheit.- 6.2 Fabry-Krankheit.- 6.3 Mukopolysaccharidosen.- 6.4 Farber-Krankheit.- 6.5 Mukolipoidosen.- 6.6 Mannosidose.- 6.7 Alkaptonurische Ochronose.- 6.8 Exogene Ochronose (Pseudoochronose).- 6.9 Fettstoffwechselstörungen.- 6.9.1 Hyperlipoproteinämien.- 6.9.2 Zerebrotendinöse Xanthomatose.- 6.9.3 Sitosterinämie.- 6.9.4 Lokale Cholesterinkristallablagerungen.- 6.9.5 Hyperlipasämie.- 6.10 Amyloidose.- 6.10.1 Allgemeine Pathogenese.- 6.10.2 Allgemeine Klassifikation.- 6.10.3 Allgemeine Epidemiologie.- 6.10.4 Amyloidosen mit Beteiligung des Bewegungssystems.- 6.10.5 Allgemeine Diagnostik.- 6.10.6 Amyloidtumoren des Bindegewebes.- 6.11 Gicht.- 6.12 Kalziumpyrophosphat-Arthropathie.- 6.13 Apatitkrankheiten.- 6.13.1 Allgemeine Pathogenese von Apatitverkalkungen.- 6.13.2 Ratifizierte Tendopathie.- 6.13.3 Milwaukee-Schulter.- 6.13.4 Apatit-Chondropathie.- 6.13.5 Tumorförmige Kalzinose.- 6.14 Oxalose.- 6.15 Hämochromatose.- 6.16 Transfusionssiderose.- 6.17 Wilson-Krankheit.- 6.18 Zystische Fibrose.- 6.19 Erblicher Adenosin-Desaminase-Mangel.- 6.20 Hypophosphatämische Vitamin-D-resistente Rachitis.- 6.21 Hypophosphatasie.- Literatur.- 7 Chemische Noxen und Pharmaka.- 7.1 Aluminium.- 7.2 Beryllium.- 7.3 Blei.- 7.4 Fluor.- 7.5 Graphit.- 7.6 Natriummonojodacetat.- 7.7 Thallium.- 7.8 Wismut.- 7.9 Zink.- 7.10 Kashin-Beck-Krankheit.- 7.11 Mseleni-Krankheit.- 7.12 Familiäre Arthrose von Malnad.- 7.13 Herz-Kreislauf-Medikamente.- 7.14 Protonenpumpenhemmer.- 7.15 Eosinophilie-Myalgie-Syndrom.- 7.16 Gyrasehemmer.- 7.17 Tetrazykline.- 7.18 Interferon-?.- 7.19 Kokain.- 7.20 Morphin.- 7.21 Toxisches Öl-Syndrom.- 7.22 Tumor-Chemotherapie.- 7.23 Vitamin A.- 7.24 „Golfkrieg-Myalgie-Syndrom“.- 7.25 Lathyrismus.- 7.26 Papain.- Literatur.- 8 Neurologische Krankheiten.- 8.1 Neuropathische Arthropathie.- 8.2 Sudeck-Syndrom.- Literatur.- 9 Durchblutungsstörungen.- 9.1 Osteochondrosis dissecans.- 9.2 Freie Gelenkkörper.- 9.3 Große ischämische Knochennekrosen.- 9.4 Calvé-Legg-Perthes-Krankheit.- 9.5 Ischämische Fasziitis.- Literatur.- 10 Gelenkblutungen.- 10.1 Lokale Schädigungen.- 10.2 Gerinnungsstörungen.- 10.2.1 Erworbene Gerinnungsstörungen.- 10.2.2 Hämophile Arthropathie.- Literatur.- 11 Entzündungen bekannter Ätiologie.- 11.1 Viren.- 11.1.1 Arthritis.- 11.1.2 Tendosynovialitis.- 11.1.3 Bursitis.- 11.2 Bakterien.- 11.2.1 Uncharakteristische bakterielle Arthritis.- 11.2.2 Uncharakteristische bakterielle Tendosynovialitis.- 11.2.3 Uncharakteristische bakterielle Bursitis.- 11.2.4 Nekrotisierte Fasziitis.- 11.2.5 Uncharakteristische bakterielle Spondylitis.- 11.2.6 Tuberkulöse Arthritis.- 11.2.7 Sonderformen tuberkulöser Arthritiden.- 11.2.8 Tuberkulöse Tendosynovialitis.- 11.2.9 Sonderformen granulomatöser Tendosynovialitiden.- 11.2.10 Tuberkulöse Bursitis.- 11.2.11 Tuberkulöse Spondylitis.- 11.2.12 Brucellose.- 11.2.13 Lepra.- 11.2.14 Syphilis.- 11.3 Pilze.- 11.3.1 Arthritis.- 11.3.2 Tendosynovialitis.- 11.3.3 Bursitis.- 11.3.4 Spondylitis.- 11.4 Parasiten.- 11.4.1 Arthritis.- 11.4.2 Tendosynovialitis.- 11.5 Algen.- 11.5.1 Tendosynovialitis.- 11.5.2 Bursitis.- 11.6 Fremdmaterialien.- 11.6.1 Pflanzendornensynovialitis.- 11.6.2 Seeigelstachelsynovialitis.- 11.7 Serumkrankheit.- Literatur.- 12 Chronische Gelenkentzündungen.- 12.1 Chronische Polyarthritis.- 12.1.1 Historische Daten.- 12.1.2 Rheumafaktoren.- 12.1.3 Epidemiologie.- 12.1.4 Klinische Symptome.- 12.1.5 Ätiologie.- 12.1.6 Allgemeine Pathogenese.- 12.1.7 Pathomorphologie.- 12.1.8 Sonderformen.- Felty-Syndrom.- Juvenile chronische Arthritis.- Still-Syndrom des Erwachsenen.- Alters-cP.- 12.2 Klassische Spondylarthritiden.- 12.2.1 Ankylosierende Spondylitis.- 12.2.2 Psoriasisarthritis.- 12.3 Reaktive Arthritiden.- 12.3.1 Akutes rheumatisches Fieber.- 12.3.2 Lyme-Krankheit (Borreliose).- 12.3.3 Reiter-Syndrom.- 12.3.4 Enteropathische Arthritiden.- Colitis ulcerosa.- Morbus Crohn.- Morbus Whipple.- Colitis collagenosa.- Zöliakie.- Cronkhite-Canada-Syndrom.- Intestinale Anastomosen.- Bakterielle Darmentzündungen.- 12.3.5 Tumorassoziierte „rheumatische“ Symptome.- 12.3.6 Arthritis bei periartikulären Tumoren.- 12.3.7 Nahrungsmittelallergie.- 12.3.8 Sympathische Gelenkergüsse.- 12.3.9 Heterologes Kollagen.- 12.3.10 Bursitis bei Asthma bronchiale.- 12.3.11 Fasziitis bei Tumoren.- 12.4 Systemische entzündliche Krankheiten.- 12.4.1 Systemischer Lupus erythematodes.- 12.4.2 Systemische Sklerose.- 12.4.3 Polymyositis/Dermatomyositis.- 12.4.4 Gemischtes Bindegewebserkrankungssyndrom.- 12.5 Entzündungen unklarer Zugehörigkeit.- 12.5.1 Sarkoidose.- 12.5.2 Rezidivierende Polychondritis.- 12.5.3 Sjögren-Syndrom.- Primäres Sjögren-Syndrom.- 12.5.4 Familiäres Mittelmeerfieber.- 12.5.5 Fibroblastischer Rheumatismus.- 12.5.6 Familiäre Arthritiden.- 12.5.7 Morbus Behçet.- 12.5.8 Arthritiden bei Dermatitiden.- Akne.- Pustulosis palmaris und plantaris.- Sweet-Syndrom.- 12.5.9 Tietze-Syndrom.- 12.5.10 Transitorische Synovialitis des Hüftgelenks.- 12.5.11 Arthritiden bei chromosomalen Störungen.- 12.5.12 Menstruationsarthritis.- 12.5.13 Malakoplakie.- 12.5.14 Idiopathisches Hypereosinophilie-Syndrom.- 12.5.15 Palindromischer Rheumatismus.- 12.5.16 Hydrops intermittens.- 12.5.17 Eosinophile Fasziitis.- 12.6 Vaskulitische Syndrome.- 12.6.1 Riesenzellen-(Temporal-) Arteriitis.- 12.6.2 Takayasu-Arteriitis.- 12.6.3 Polyarteriitis nodosa und mikroskopische Polyangiitis.- 12.6.4 Kawasaki-Syndrom.- 12.6.5 Wegener-Granulomatose.- 12.6.6 Churg-Strauss-Syndrom.- 12.6.7 Henoch-Schönlein-Purpura.- 12.6.8 Essentielle Kryoglobulinämie.- 12.6.9 Kutane leukozytoklastische Angiitis.- Literatur.- 13 Mechanische Schädigungen.- 13.1 Gelenke.- 13.1.1 Einmalige direkte Traumen.- 13.1.2 Arthrose.- Historische Daten.- Definition.- Epidemiologie.- Klinische Symptome.- Ätiologie.- Pathogenese.- Pathomorphologie.- 13.1.3 Sonderformen der Arthrose.- Fingerpolyarthrosen.- Erosive Arthrose.- 13.1.4 Baker-Zyste.- 13.2 Gelenkzwischenscheiben und -lippen.- 13.2.1 Meniskopathie.- 13.2.2 Diskopathie.- 13.2.3 Labropathie.- 13.3 Zwischenwirbelscheiben.- 13.3.1 Diskopathie.- 13.3.2 Verlagerung von Zwischenwirbelscheibengeweben.- 13.3.3 Spondylose.- 13.3.4 Spondylarthrose.- 13.3.5 Osteochondrosis juvenilis.- 13.3.6 Diskusverkalkungen im Kindesalter.- 13.4 Sehnen.- 13.4.1 Allgemeine Pathogenese von Tendopathien.- 13.4.2 Partielle Kontinuitätsdurchtrennungen.- Tendinosen.- Tendovaginopathia crepitans.- Tendovaginopathia stenosans.- Karpaltunnelsyndrom.- Impingement-Syndrom.- Periarthropathia humeroscapularis.- 13.4.3 Insertionstendopathie.- 13.4.4 Besonderheiten der Wirbelsäule.- 13.4.5 Komplette Kontinuitätsdurchtrennungen.- Allgemeine Pathogenese.- Spezielle Sehnenrupturen.- Pathomorphologie kompletter Sehnenrupturen.- Gutachterliche Beurteilung von Sehnenrupturen.- 13.5 Bursen.- 13.5.1 Hämatobursa.- 13.5.2 Chronische Bursopathie.- 13.5.3 Neubildung von Bursen.- 13.5.4 Baker-Zyste.- Literatur.- 14 Tumoren.- 14.1 Benigne Tumoren.- 14.1.1 Pigmentierte villonoduläre Synovialitis.- 14.1.2 Primäre synoviale Osteochondromatose.- 14.1.3 Paraartikuläres Osteochondrom.- 14.1.4 Multizentrische Retikulohistiozytose.- 14.1.5 Lipoma arborescens.- 14.1.6 Lipom.- 14.1.7 Fibrom.- 14.1.8 Hämangiom.- 14.1.9 Juxtaartikuläres Myxom.- 14.1.10 Endometriose.- 14.1.11 Ganglien.- 14.2 Maligne Tumoren.- 14.2.1 Synoviales Sarkom.- 14.2.2 Maligner Riesenzellentumor.- 14.2.3 Chondrosarkom.- 14.2.4 Tumormetastasen.- 14.2.5 Infiltrate lymphohämatopoetischer Krankheiten.- 14.2.6 Klarzellensarkom.- 14.2.7 Epitheloides Sarkom.- 14.3 Fibromatosen.- 14.3.1 Fibromatose der Palmaraponeurose.- 14.3.2 Fibromatose der Plantaraponeurose.- 14.3.3 Fingerknöchelpolster.- 14.3.4 Induratio penis plastica.- 14.3.5 Kalzifiziertes Aponeurosenfibrom.- 14.3.6 Infantile digitale Fibromatose.- 14.3.7 Juvenile hyaline Fibromatose.- 14.3.8 Noduläre Fasziitis.- 14.3.9 Proliferative Fasziitis.- 14.3.10 Elastofibrom.- 14.3.11 Desmoidtumor.- 14.4 Chordom.- Literatur.- 15 Paraartikuläre Krankheiten.- 15.1 Paraartikuläre Ossifikation.- 15.2 Juxtaartikuläre Adipositas dolorosa.- 15.3 Periartikuläre Fibrose.- 15.4 Hypertrophe Osteoarthropathie.- 15.4.1 Idiopathische hypertrophe Osteoarthropathie.- 15.4.2 Sekundäre hypertrophe Osteoarthropathie.- 15.5 Fibromyalgie-Syndrom.- 15.6 Morton-Metatarsalgie.- Literatur.- 16 Folgen artikulärer Therapien.- 16.1 Systemische Therapie.- 16.1.1 Gold.- 16.1.2 Nichtsteroidale Antiphlogistika.- 16.1.3 Medikamentöse Knorpeltherapie.- 16.2 Intraartikuläre Therapie.- 16.2.1 Silikonflüssigkeit.- 16.2.2 Hyaluronat.- 16.2.3 Polyvinylpyrrolidonhaltige Medikamente.- 16.2.4 Glukokortikoide.- 16.2.5 Synoviorthese.- Chemische Synoviorthese.- Radio synoviorthese.- 16.2.6 „Gentransfer-Therapie“.- 16.2.7 Operative Synovialektomie.- 16.2.8 Lasereingriffe.- 16.2.9 Gelenkersatz-(Endoprothesen-)operationen.- Abriebprodukte.- Maligne Tumoren.- Mechanismen der Prothesenlockerung.- Reaktion auf Apatit.- Paraprothetische Ossifikation.- Infektionen.- 16.2.10 Débridement-Operation.- 16.2.11 Therapie osteokartilaginärer Defekte.- 16.2.12 Therapie von Meniskusdefekten.- 16.2.13 Therapie von Sehnendefekten.- 16.2.14 Komplikationen der Arthroskopie.- 16.3 Perkutane Therapie.- 16.3.1 Ultraschalltherapie.- 16.3.2 Extrakorporale Stoßwellentherapie.- 16.3.3 Photodynamische Therapie.- 16.4 Chemonukleolyse.- 16.5 Historische Erinnerung.- Literatur.- Verzeichnis bemerkenswürdiger Autoren der älteren Literatur.

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Book SynopsisSkeletal Muscle Mechanics: From Mechanisms to Function summarises the variety of approaches used by todaya s scientist to understand muscle function and the mechanisms of contraction. This book contains research by leading scientists from numerous fields using many different scientific techniques.Table of ContentsPartial table of contents: MECHANISMS OF MUSCLE CONTRACTION. Considerations on the Mechanisms of Muscular Contraction (W. Herzog). Cross-bridge Action: Present Views, Prospects, and Unknowns (A. Huxley). THEORETICAL MODELLING OF MUSCLE AND MUSCLE CONTRACTION. Considerations on the Theoretical Modelling of Skeletal Muscle Contraction (W. Herzog). The Two-state Cross-bridge Model as a Link Between Molecular and Macroscopic Muscle Mechanics (G. Zahalak). Three-dimensional Geometric Model of Skeletal Muscle (R. Lemos, et al.). IN VIVO MUSCLE FUNCTION (HUMAN). Considerations on In Vivo Muscle Function (W. Herzog). In Vivo Mechanics of Maximum Isometric Muscle Contraction in Man: Implications for Modelling-based Estimates of Muscle Specific Tension (C. Maganaris & V. Baltzopoulos). Muscle Inhibition and Functional Deficiencies Associated with Knee Pathologies (E. Suter & W. Herzog). Effects of Ageing on Eccentric and Concentric Muscle Torque Production in Lower and Upper Limbs (A. Vandervoort, et al.). IN VIVO MUSCLE FUNCTION (ANIMAL). In Vivo Function and Functional Design in Steady Swimming Fish Muscle (S. Katz & R. Shadwick). Visco-Elastic Properties of Cardiac Trabeculae: Re-examination of Diastole (B. Stuyvers, et al.). Index.

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Book SynopsisBONE AND JOINT INFECTIONS Explore this comprehensive presentation of bone and joint infections, including non-implant and implant-associated orthopedic infectionsIn the newly revised Second Edition of Bone and Joint Infections: From Microbiology to Diagnostics and Treatment, accomplished researcher and author Werner Zimmerli delivers a comprehensive overview of the most recent developments in the subject of bone and joint infection. Covering much of the new information appearing over the last five years, the book includes four new chapters presenting the diagnostic approach in bone and joint infections, discussing the identification of pathogens by non-culture techniques, management of multi-resistant bacteria in bone and joint infections by bacteriophages, and unusual microorganisms in periprosthetic joint infections.Many of the chapters are also updated to include new information on topics like eubacterial PCR, multiplex PCR, and the shotgun metagenomicsTable of ContentsList of Contributors xii Preface to the Second Edition xvi Foreword to the First Edition xvii Acknowledgments xix Chapter 1 Introduction 1Werner Zimmerli Chapter 2 Diagnostic Approach in Bone and Joint Infections 5Nora Renz, Donara Margaryan, and Andrej Trampuz Introduction 5 Common Microorganisms Causing Bone and Joint Infection 7 Diagnostic Approach in Spinal Infection 8 Diagnostic Approach in Bone Fixation Device‐Associated Infection 10 Diagnostic Approach in Native Arthritis and Infections after Anterior Cruciate Ligament Repair (ACL‐R) 12 Diagnostic Approach in Periprosthetic Joint Infections (PJI) 15 Key Points 17 References 17 Chapter 3 Unusual Microorganisms in Periprosthetic Joint Infection 21Camelia Marculescu and Werner Zimmerli Introduction 21 Gram‐Positive Microorganisms 21 Gram‐Negative Microorganisms 26 Zoonotic Microorganisms 29 Anaerobic Microorganisms 34 Mycobacteria 35 Other Microorganisms 38 Key Points 40 References 40 Chapter 4 Identification of Pathogens in Bone and Joint Infections by Non‐Culture Techniques 51Maria Eugenia Portillo and Stephane Corvec Introduction 51 Broad‐Range PCR 51 Targeted PCR 53 Multiplex PCR 54 Next‐Generation Sequencing Approach 55 Mass Spectrometry‐Based Methods 58 Key Points 61 References 61 Chapter 5 Bacteriophages for Treatment of Biofilm Infections 65Mercedes Gonzalez‐Moreno, Paula Morovic, Tamta Tkhilaishvili, and Andrej Trampuz History of Bacteriophage Use in Human Infections 65 Principles of Bacteriophage Therapy 66 Activity of Bacteriophages against Bacterial Biofilms and Persisters 69 Bacteriophage Susceptibility Testing: the Phagogram 71 Experimental and Clinical Evidence with Bacteriophage Treatment 72 Local Delivery and Systemic Bacteriophage Application 74 Outlook and Future Perspectives 76 Key Points 77 References 78 Chapter 6 Pharmacokinetics and Pharmacodynamics of Antibiotics in Bone 81Cornelia B. Landersdorfer, Jurgen B. Bulitta, Roger L. Nation, and Fritz Sorgel Pharmacokinetics 81 Bone Sample Preparation and Analysis 82 Pharmacokinetic Sampling and Data Analysis 83 Penetration of Antibiotics into Bone 84 Pharmacodynamics and Monte Carlo Simulations 93 Conclusions 95 Key Points 96 References 96 Chapter 7 Preclinical Models of Infection in Bone and Joint Surgery 99Caroline Constant, Lorenzo Calabro, Willem‐Jan Metsemakers, R. Geoff Richards, and T. Fintan Moriarty Introduction 99 Influence of Species in Preclinical Models of Bone and Joint Infection 100 Overview of Animal Models 103 Direct Inoculation with Minimal Trauma 103 Animal Models of Bone and Joint Infection Incorporating Trauma 108 Hematogenous Models 108 Future Directions 109 Conclusions 110 Key Points 110 References 110 Chapter 8 Native Joint Arthritis in Children 117Pablo Yagupsky Introduction 117 Epidemiology 117 Microbiology 118 Pathogenesis 122 Clinical Presentation 123 Laboratory Investigation 125 Imaging Studies 127 Differential Diagnosis 128 Treatment 128 Prognosis 133 Key Points 134 References 134 Chapter 9 Native Joint Arthritis in Adults 139Florian B. Imhoff, David E. Bauer, and Ilker Uckay Introduction 139 Risk Factors 139 Pathogenesis, Epidemiology, and Microbiology 140 Diagnosis 141 Treatment 144 Outcome 147 Key Points 148 Acknowledgments 148 References 148 Chapter 10 Septic Arthritis of Axial Joints 151Werner Zimmerli Septic Arthritis of the Sternoclavicular Joint 151 Key Points 157 Septic Arthritis of the Symphysis Pubis 157 Key Points 161 Septic Arthritis of the Sacroiliac Joint 161 Key Points 165 References 165 Chapter 11 Periprosthetic Joint Infection: General Aspects 171Werner Zimmerli Introduction 171 Definition 172 Classification 172 Pathogenesis 172 Laboratory Investigation 176 Therapeutic Management 178 Prophylaxis 179 Errors in the Management of PJI 180 Key Points 180 References 181 Chapter 12 Periprosthetic Joint Infection after Total Hip and Knee Arthroplasty 187Werner Zimmerli, Rihard Trebse, and Martin Clauss Introduction 187 Risk Factors 188 Microbiology 188 Clinical Features 189 Laboratory Investigation 190 Imaging Procedures 191 Management 192 Instructive Cases 202 References 206 Chapter 13 Periprosthetic Joint Infection after Shoulder Arthroplasty 213Parham Sendi, Andreas Marc Muller, Beat K. Moor, and Matthias A. Zumstein Introduction 213 Risk Factors 213 Microbiology 215 Pathogenesis 216 Clinical Features 217 Laboratory Investigation 218 Imaging Procedures 220 Management 220 Instructive Cases 224 References 226 Chapter 14 Periprosthetic Joint Infection after Elbow Arthroplasty 231Yvonne Achermann, Michael C. Glanzmann, and Christoph Spormann Introduction 231 Microbiology 232 Clinical Features 232 Diagnostic Procedures 234 Management 237 Instructive Cases 242 References 245 Chapter 15 Periprosthetic Joint Infection after Ankle Arthroplasty 251Parham Sendi, Bernhard Kessler, and Markus Knupp Introduction 251 Risk Factors 252 Microbiology 254 Clinical Features 254 Laboratory Investigation 255 Imaging Procedures 256 Management 257 Instructive Cases 260 References 262 Chapter 16 Osteomyelitis: Classification 265Werner Zimmerli Classification According to Pathogenesis 265 Classification According to the Duration of Infection 267 Classification According to the Localization 268 Classification According to the Presence of an Implant 269 Classification According to Anatomy and Comorbidity 269 References 270 Chapter 17 Osteomyelitis in Children 273Alexander Aarvold, Priya Sukhtankar, and Saul N. Faust Introduction 273 Epidemiology 273 Pathophysiology 274 Clinical Presentation, Diagnosis, and Microbiology 275 Treatment 282 Complications 284 Key Points 285 References 286 Chapter 18 Acute Osteomyelitis in Adults 289Werner Zimmerli Introduction 289 Pathogenesis 289 Epidemiology 290 Microbiology 291 Risk Factors 293 Clinical Features 295 Laboratory Investigation 296 Imaging Procedures 298 Clinical and Imaging Differential Diagnosis 300 Treatment 301 Key Points 304 References 304 Chapter 19 Subacute Osteomyelitis: Tuberculous and Brucellar Vertebral Osteomyelitis 309Juan D. Colmenero and Pilar Morata Introduction 309 Epidemiology 309 Clinical Features 310 Laboratory Investigation 312 Imaging Procedures 315 Antimicrobial and Surgical Therapy 318 Key Points 321 References 321 Chapter 20 Chronic Osteomyelitis in Adults 325Felix W.A. Waibel, Benedikt Jochum, and Ilker Uckay Introduction 325 Pathogenesis 326 Diagnosis 326 Treatment 328 Key Points 333 Acknowledgments 333 References 333 Chapter 21 Diabetic Foot Osteomyelitis 337Eric Senneville and Olivier Robineau Introduction 337 Classification 337 Microbiology 339 Risk Factors 341 Clinical Features 342 Inflammatory Parameters 342 Imaging Procedures 343 Treatment 344 Prevention 347 References 348 Chapter 22 Osteomyelitis of the Jaws 353Werner Zimmerli Introduction 353 Classification 353 Microbiology 355 Risk Factors 356 Clinical Features 356 Laboratory Investigation 359 Imaging Procedures 360 Management 361 Key Points 363 References 364 Chapter 23 Fracture‐Related Infection of the Long Bones 367Parham Sendi, Mario Morgenstern, Willem‐Jan Metsemakers, and Martin McNally Introduction 367 Classification and Risk Factors 368 Microbiology 370 Clinical Features 371 Laboratory Investigation 372 Imaging Procedures 373 Management 373 Instructive Cases 380 References 383 Chapter 24 Implant‐Associated Vertebral Osteomyelitis 387Todd J. Kowalski and Arick P. Sabin Introduction 387 Classification and Risk Factors 388 Microbiology 389 Clinical Features 393 Diagnostic Procedures 393 Treatment 395 Instructive Cases 402 References 404 Chapter 25 Postoperative Sternal Osteomyelitis 409Parham Sendi, Mihai Constantinescu, and Lars Englberger Introduction 409 Risk Factors 410 Microbiology 414 Clinical Features 414 Laboratory Investigation 415 Imaging Procedures 417 Management 417 Instructive Cases 422 References 425 Index 429

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Book SynopsisDespite public perception, osteoporosis remains a widespread, devastating disease, and a very serious and costly public health threat. Early detection and treatment must be a priority for primary health care providers. Dual-energy X-ray absorptiometry (DXA) is the principal x-ray technology used to diagnose osteoporosis in its early, asymptomatic stages, to assess treatment efficacy, and to guide treatment decisions. It remains the gold standard today. A DXA Primer for the Practicing Clinician: A Case-Based Manual for Understanding and Interpreting Bone Densitometry is developed around real cases of patients'' DXA measurements. The content is derived from presentations given by the authors at a national society training course and exemplifies not only the complete body of education provided through these lectures but the full range of previously undiscussed nuancTrade ReviewFrom the reviews:“This book details the practical aspects of requesting and interpreting the results of the bone densitometry test. … This is a valuable book for clinicians who order this test, patients who are being referred for the examination, and administrators who fund the studies, because it has a relatively high value clinically although misunderstood. This book should be in every training program library.” (Vincent F. Carr, Doody’s Book Reviews, March, 2014)Table of ContentsIntroduction What prompted the authors to write this text A brief comment on the Bone & Joint Decade A brief word on the epidemiology of osteoporosis Primary disease Secondary disease That seen in chronic disease, due to Rx, men, bariatric surgery pts. Introduction to Densitometry The gold standard for non-invasive skeletal assessment Ultimate goal: prevent fractures Limitations: only a ‘snap-shot’; can not reveal what has gone on with the bones up to that point The many challenges of DXA Obtaining the images Interpreting the data Even radiologists are prone to errors Specific training is essential Clinical application to the individual patient Looking into the future New technologies Vision of an ‘optimal’ noninvasive, accurate, measure of bone quality Chief Medical Officer aboard the USS Enterprise: Lt Commander Leonard "Bones" McCoy Hand-held ‘tricorder’ 3D-QCT Finite element analysis (FEA) SECTION I: Fundamental Concepts1. The History of Non-Invasive Skeletal Assessment Imaging Techniques Radiographic absorptiometry SPA DPA QCT DXA QUS PIXI 2. Common Terms and Abbreviations Defined Accuracy Apparent bone mineral density BMD = areal density in g/cm2 in this text Areal vs. volumetric Bone accretion Bone markers Bone Mineral Density Coefficient of variation Database Distal 3rd Radius DPA DXA, Central DXA, Peripheral Femoral Neck Femoral Shaft FRAX – incl application limited to untreated pts. - should not be completed by Techs; emphasize importance of clinical judgment Hip, Total LSC Lumbar spine (L1 – L4)

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Book SynopsisFor eight decades the Primer on the Rheumatic Diseases has been the standard text from which most medical students and house ofcers have learned rheumatology. I myself will never forget thumbing through an older edition of the Primer as a second-year resident, while waiting to review a perplexing patient with my tutor. Fortunately the tutor was r- ning late with his own patients, so I had time to fip through the book – then much thinner – a couple of times. While turning the pages, per- ing the features of those diseases whose names were still exotic to me, and considering my patient’s history of conductive hearing loss and p- monary nodules, a light went on when I stumbled eventually on a part- ular chapter. I still remember the jaw-dropping efect on my tutor of my announcement then that I had a patient with Wegener’s granulomatosis. I think I became a rheumatologist that very moment! Subsequent editions of the Primer have sufered from the inevitable “obesity creep,” making it an outstanding reference textbook but virtually impossible to fip through quickly while awaiting one’s tutor, and even more difcult to slip into the pocket of a white coat to carry on rounds. For this reason we have created the Pocket Primer, a mini version that cuts the larger book down to its essentials.Table of ContentsHistory and Physical Examination.- Laboratory Assessment.- Arthrocentesis and Synovial Fluid Analysis.- Imaging Techniques.- Monarticular Joint Disease.- Polyarticular Joint Disease.- Regional Rheumatic Pain Syndromes.- Fibromyalgia and Diffuse Pain Syndromes.- Rheumatoid Arthritis.- Juvenile Idiopathic Arthritis.- Psoriatic Arthritis.- Ankylosing Spondylitis.- Reactive and Enteropathic Arthritis.- Osteoarthritis.- Calcium Pyrophosphate Dihydrate, Hydroxyapatite, and Miscellaneous Crystals.- Infectious Disorders.- Systemic Lupus Erythematosus.- Antiphospholipid Syndrome.- Systemic Sclerosis.- Idiopathic Inflammatory Myopathies.- Metabolic Myopathies.- Sjögren’s Syndrome.- Vasculitides.- Behçet’s Syndrome.- Adult Still’s Disease.- Autoinflammatory Disorders/Periodic Syndromes.- Less Common Arthropathies.- Complex Regional Pain Syndrome.- Osteonecrosis.- Paget’S Disease.- Osteoporosis.- Therapeutic Injections.- Nonsteroidal Anti-Inflammatory Drugs.- Glucocorticoids.- Operative Treatment.- Complementary and Alternative Therapies.

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Book SynopsisThis exciting book reflects the multidisciplinary approach that has proved so beneficial to the care of the rheumatology patient. Written by well qualified members of the various professions involved in this field, the book examines the full range of treatment and care of the patient. This book will prove invaluable to nurses, occupational therapists, podiatrists, physiotherapists, social workers and dieticians.Table of ContentsContributors vii Preface ix Chapter 1 1 Chapter 2 12 Chapter 3 46 Chapter 4 68 Chapter 5 98 Chapter 6 143 Chapter 7 186 Chapter 8 223 Chapter 9 244 Chapter 10 257 Chapter 11 272 Chapter 12 290 Index 321

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Book SynopsisThis book provides a concise and up-to-date review of key rheumatology topics along with extensive practice questions to assist in preparing for the American Board of Internal Medicine (ABIM) Rheumatology Certification Exam.Each chapter focuses on a single disease and starts with a short review (primarily tables and figures) to highlight the main points and key issues. The review is followed by 10-20 board-style multiple choice questions with detailed explanations for each topic. The chapters and associated preparation questions are written by established experts from top institutions in the United States. The book concludes with a 50-question practice test reflecting the format used by the ABIM Board Certification Exam.Absolute Rheumatology Review is an essential resource for not only graduate students, residents, and fellows in rheumatology and internal medicine studying for board exams but also rheumatologists, physicians, and related professionals preparing for recertification.Table of ContentsIntroduction.-Immunological Basis of Inflammatory Arthritides.-Clinical Epidemiology for Rheumatologists.-Osteoarthritis.-Regional Musculoskeletal Syndromes and the use of MSK Ultrasound.-Infectious Arthritis.-Rheumatoid Arthritis.-Psoriatic Arthritis.-Axial Spondyloarthritis.-Systemic Lupus Erythematosus.-Sjogren's Syndrome.-Systemic Sclerosis (Scleroderma).-Vasculitis.-Inflammatory Myopathies.-Osteoporosis.-Crystal Arthritis.-Autoinflammatory Diseases.-Pediatric Rheumatology for Adult Rheumatologists.-Musculoskeletal Manifestations of Systemic Diseases.-Clinical Genetics in Rheumatology

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Book SynopsisThis book answers questions about the critical role of ultrasound in the management of patients with Sjögren’s syndrome. It also covers developments rheumatologists can foresee in performing a biopsy of the parotid gland. Each chapter is authored by experts on this condition, emphasizing the extent of current understanding and dealing with unanswered challenges and pitfalls. Topics such as modern imaging techniques like ultrasound and MRI and their importance are given particular focus in this book; practitioners are increasingly using imaging techniques to refine diagnosis and guide clinical management. Additionally, as a significant emerging point of interest in the field, biopsy of the major salivary glands, particularly ultrasound-guided procedures, receives extra attention within the text. The book also includes a chapter that deals with future directions and will also review the challenges patients face with unmanaged Sjögren’s syndrome. Comprehensive and concise, Sjögren’s Syndrome and the Salivary Glands provides a balanced overview between the chapters and ensure homogeneity of the terminology. Table of ContentsCh 1. Introduction Ch 2. Epidemiology Ch 3. Pathogenesis of Sjögren’s syndrome Ch 4. Anatomy of the major salivary glands Ch 5. Imaging of Sjögren’s syndrome Ch 6. Sonoanatomy of the major salivary glandsCh 7. Ultrasound of Sjögren’s syndromeCh 8. MRI in the management of Sjögren’s syndromeCh 9. Biopsy of the minor salivary glandsCh 10 Biopsy of the major salivary glandsCh 11.Pitfalls and future directions

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Book SynopsisThe book examines recent developments in regenerative medicine and the use of musculoskeletal ultrasound. Musculoskeletal regeneration has become a prominent research topic, no doubt due to the sociological and economic pressures imposed by the current ageing population. The ever expanding role of regenerative medicine and the identification as well as characterization of stem cells have introduced a major paradigm shift in the field of musculoskeletal and sports medicine as well as orthopaedic surgery. Whereas in the past, diseased tissue was replaced with allograft material, current trends in research revolve around regenerating damaged tissue.Specifically, regenerative medicine stands in contrast to the standard treatment modalities which impair the body’s natural abilities to facilitate endogenous repair mechanisms such as anti-inflammatory drugs; or destructive modalities (e.g., radiotherapy, nerve ablation, injections of botulinum toxin) and surgical interventions that permanently alter the functioning of a joint, bone or spine. When compared to other allopathic options (including knee and hip arthroplasty with a 90-day mortality rate of 0.7%), regenerative medicine treatment modalities have a lower incidence of adverse events with a growing body of statistically significant medical literature illustrating both their safety and efficacy. Focusing on the major values of regenerative medicine, this book with its 21 chapters is expected to fill an important void in the current literature. It will take that extra step to guide you in your day to day clinical practice. Featuring contributions from a large international group of leaders in regenerative medicine and musculoskeletal ultrasonography, this book is an authoritative reference for rheumatologists, physiatrists, sonographers, radiologists, physiotherapists and orthopaedic specialists.Table of ContentsPart I. Regenerative MedicineChapter 1. Advances in Regenerative MedicineChapter 2. Regenerative Medicine Options for Musculoskeletal UltrasoundChapter 3. Translational Regenerative MedicinePart II. Diagnostic and Interventional Musculoskeletal UltrasonographyChapter 4. Image OptimizationChapter 5. ShoulderChapter 6. ElbowChapter 7. Wrist and HandChapter 8. HipChapter 9. KneeChapter 10. Foot and AnklePart III. Back and SpineChapter 11. SpineChapter 12. SPINAL REGENERATIVE MEDICINEPart IVChapter 13. Regenerative Medicine in DentistryPart V Musculoskeletal ultrasound in Regenerative MedicineChapter 14. Regenerative Medicine Procedures under Ultrasound GuidanceChapter 15. Peripheral Nerve HydrodissectionChapter 16. High Frequency Peripheral Nerve UltrasoundChapter 17. Neural Prolotherapy under Ultrasound GuidanceChapter 18. Ultrasound-Guided Spinal ProceduresChapter 19. Musculoskeletal US for Interventional PhysiatryPart VI Sports MedicineChapter 20. Ultrasound-Guided ExercisesChapter 21. Musculoskeletal US in Sports, and Orthopedic Medicine: advantages, indications and limitations Chapter 22. Use of musculoskeletal US and Regenerative Therapies in SportsPart VII Future of Regenerative medicineChapter 23. Regenerative Medicine: challenges, perspective, and future directions

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Book SynopsisThis book details the practice of telerheumatology. Telemedicine is defined as the delivery of healthcare and the exchange of healthcare information across distances. Following, telerheumatology is the delivery of rheumatology care through telemedicine. There exists an increasing demand from patients, caregivers, and healthcare systems for access to academic specialists through telemedicine. This has been the case for the past several years and the demand has only increased with the ongoing COVID-19 pandemic. There is currently a lack of rheumatologists in rural areas and that is expected to spread to a general lack by 2025. Telerheumatology offers an excellent and timely solution to fill these gaps and provide care.Telerheumatology care has been shown to be feasible and quite effective. The current COVID-19 pandemic has thrust the concept of telemedicine into the spotlight. However, not all telerheumatology care is the same and there exists many nuances and differences when examining telerheumatology care across the United States and the world. After comprehensively reviewing the origins of telerheumatology, this work defines in detail the current practice of telerheumatology, along with the specific impact of the COVID-19 pandemic and all applications of telerheumatology. Expert authors also provide a detailed roadmap for providers to initiate, sustain, and grow a telerheumatology program. The book concludes by covering future directions of telerheumatology, including areas for expansion, improvement, and innovation.After reading this work, the editor and all the contributing authors hope that it will inspire, provoke thought and discussion, and lead to increased adaptation of providing telerheumatology care by rheumatologists and rheumatology providers.Table of Contents

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Book SynopsisDesigned to save the surgeon’s time in preparing for surgery... This operative atlas is a detailed guide to the most important standard surgical options for advanced rheumatic disease. Procedures are presented with a rich variety of color photographs and exquisite illustrations. The concept Clearly laid out representation of all standard procedures in orthopaedic surgery for rheumatic diseases, with emphasis on the hand and foot Concise and consistently structured texts make for efficient uptake of the material Adjunct information on indications, patient communications, instruments, positioning, approaches, key incisions, complications, and aftercare Detailed photographs illustrate the procedures step by step Precise drawings support comprehension of the anatomic relationships involved in each step of the procedure Contents-richly and realistically illustrated More than 400 superb images, showing all relevant details of anatomy and individual surgical steps The focus is on procedures for the hand and foot, while the elbow, shoulder, ankle, knee, hip and spine are also shown in detail Table of Contents1. Principles of Orthopaedic Rheumatology 2. The Hand 3. The Elbow 4. The Shoulder 5. The Foot 6. The Ankle 7. The Knee 8. The Hip 9. The Spine

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Book SynopsisRheuma bei Kindern ist eine bislang wenig beachtete und dennoch häufig auftretende Erkrankung. Das Buch bietet betroffenen Familien erstmals einen Überblick über Symptomatik, Diagnose und Therapieansätze. Die Autoren machen wichtige Fachbegriffe verständlich und geben ihr Expertenwissen über Anwendbarkeit und Erfolgsaussichten verschiedener medikamentöser, physio- und ergotherapeutischer Therapien weiter. Hinweise zur Selbsthilfe und ein Serviceteil komplettieren diesen Ratgeber. Auch behandelnde Ärzte erfahren viel Wissenswertes.Table of Contents1. Kindliches Rhema gibt es das? Epidemiologie, Was versteht man darunter, Häufigkeit, Genetik 2. Terminologie 2.1 Chronische Gelenksentzündungen Subtypen 2.2. Kollagenosen 2.3. Vaskulitiden Spezifische Kawasaki Syndrom u. a. 3. Differenzialdiagnosen Neoplasien 4. Diagnose welche Möglichkeiten gibt es 5. Pädiatrische Aspekte Einfluss von Wachstum, Ernährung, Ernährungszustand, Psyche, Entwicklung, Schule, Ausbildung, Sexualität, Pubertät 6. Transition (Übergang Jugendlich – Erwachsen) Klinik Gemeinsame Betreuung Pädiater und Rheumatologe 7. Therapiemöglichkeiten Medizinische, Physiotherapie, Ergotherapie

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Book SynopsisThis book has been designed to lead you through the first steps of the shoulder arthroscopy. Offering a companion guide, its numerous illustrations and videos support the text and aid in comprehension.The most common mistake in shoulder arthroscopy is to focus on the screen, whereas an external perspective is needed, though not always easy to achieve in practice. We recommend following the chronological order for the first techniques, which are then detailed one by one and can be read separately depending on the problem encountered. These techniques, all of which were developed by the author in the course of 20 years of arthroscopic surgeries, are characterized by their simplicity. After having mastered these techniques, the reader will have the basis needed to evolve on his or her own.Table of ContentsPrefaces.- Introduction.- Chapter 1 Being in the right conditions.- 1.1 Avoiding steam.- 1.2 Properly entering the shoulder.- 1.3 Avoiding blood.- Chapter 2 Being properly installed.- 2.1 Installing the patient.- 2.2 The surgeon's ergonomy.- Chapter 3 Basic essentials.- 3.1 Stable image.- 3.2 Straight image.- 3.3 Finding your instruments.- Chapter 4 Exploring the shoulder.- 4.1 The glenohumeral.- 4.2 The subacromial space.- Chapter 5 Tips for the key surgeries.- 5.1 Before the surgical arthroscopy.- 5.2 The rotator cuff.- 5.3 The subscapularis.- 5.4 The biceps.- 5.5 Instability and the arthroscopic Bankart.- Chapter 6 Less frequent surgeries.- 6.1 The acromioclavicular.- 6.2 The subscapularis nerve.- Chapter 7 How to evolve your techniques.- 7.1 Analyze your mistakes, travel and create.- Conclusion.

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Book SynopsisDieses Buch setzt Standards im Verständnis von Biomechanik und ligamentären Rekonstruktionstechniken des wohl kompliziertesten Gelenks des menschlichen Körpers. Von der funktionellen Anatomie zur optimalen Therapie, das war der Grundgedanke, den Prof. Werner Müller seinem 1982 erschienenen Buch „Das Knie – Form, Funktion und ligamentäre Wiederherstellungschirurgie“ zu Grunde legte. Unter diesem Gesichtspunkt, der die 1. Auflage sehr erfolgreich machte, hat das Team Jagodzinski, Friederich und Müller das Werk auf den neuesten medizinischen Stand gebracht.Trade Review“… wendet sich an den orthopädischen Chirurgen, der allerbestens vertraut ist mit der pathologischen Anatomie des Knies … Der interessierte Leser wird besonders die umfassende Erfahrung schätzen, die in diesem Werk zu Bandrekonstruktion und Rehabilitation zum Ausdruck kommt; finden sich hierin doch vierzig Jahre an Erfahrung in diesem äußerst weiten und komplexen Forschungsgebiet. Dies zusammengetragen von hervorragenden Klinikern, die an vorderster Front standen und stehen, stets bemüht im Interesse der Patientenbehandlung und Fürsorge.” (R. Verdonk, in: Der Orthopäde, Heft 12, 1. Dezember 2017)Table of ContentsTeil I Anatomie.- Kinematik.- Rotation.- Untersuchung des verletzten Kniegelenks.- Teil II Verletzung der Kapsel und der Bänder.- Allgemeine Operationstechnik.- Die primäre Rekonstruktion der speziellen Verletzungen.- Die sekundäre Rekonstruktion und der plastische Ersatz bei der veralteten Verletzung.- Die postoperative Rehabilitation.

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Book SynopsisDescribes the clinical approach to an organ of sense and motion unique as the 'foot-ankle' through the educational model of the iconographic narrative, useful to the doctor to recognize the paramorphisms of pathological pictures. The purpose is to illustrate the clinical approach according to the authors' experiences.

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Book SynopsisSjögren's Syndrome summarises current understanding of the pathogenesis of the disease, including advances in the genetics, disease mechanisms, clinical diagnosis and assessment, secondary Sjögren's syndrome, and the role of laboratory investigations and imaging.Trade ReviewThe volume contains well written, succinct, and comprehensive chapters on disease mechanisms, diagnosis, assessments, and laboratory investigations. The layout is pleasing, and each chapter has key points highlighted at the beginning. Chapters are easy to read with useful subheadings and plenty of summary tables and figures showing important mechanisms and pathways of care. This book is indispensable for all interested and involved in the care of the patients with Sjögren's syndrome. * Dr. Vinod Ravindran, Indian Journal of Rheumatology *

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a huge range and FREE tracked UK delivery on ALL orders.

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