Pharmacy / dispensing Books

1214 products


  • Pharmaceutical Press Lecture Notes in Pharmacy Practice

    Out of stock

    Book SynopsisA comprehensive study/revision guide which summarises the basic principles in pharmacy practice. It covers essential information in the following five sections: introduction to pharmacy; clinical pharmacy and pharmacotherapeutics; responding to symptoms in community pharmacy; pharmacy information and research; and pharmacy systems.Table of Contents1. Historical Perspectives: 2. Pharmacy Practice and the Healthcare System: 3. Medicine Presentation and Administration: 4. Medicine Safety: 5. Community Pharmacy Practice: 6. Dispensing Prescriptions: 7. Health Promotion: 8. Communication Skills and Patient Counselling: 9. Compliance, Adherence and Concordance: 10. Mathematical Principles of Drug Therapy: 11. Point-of-Care Testing: 12. Pharmaceutical Care Plans: 13. Medicine Action: 14. Clinical Pharmacokinetics: 15. Constipation and Diarrhoea: 16. Gastro-oesophageal Reflux Disease and Peptic Ulcer Disease: 17. Inflammatory Bowel Disease and Other Chronic Bowel Disorders: 18. Emesis: 19. Cardiovascular Disorders: 20. Hypertension: 21. Ischaemic Heart Disease: 22. Congestive Heart Failure: 23. Hyperlipidaemia: 24. Thrombosis: 25. Asthma, Chronic Obstructive Pulmonary Disorder and Allergic Rhinitis: 26. Schizophrenia: 27. Mood Disorders: 28. Anxiety Disorders: 29. Sleep Disorders: 30. Eating Disorders: 31. Pain Management and Fever: 32. Dementia and Alzheimer's Disease: 33. Parkinson's Disease: 34. Anti-infective Agents: 35. Human Immunodeficiency Virus Infection: 36. Viral Hepatitis: 37. Thyroid Disorders: 38. Diabetes Mellitus: 39. Menopause and Hormone Replacement Therapy: 40. Menstrual Cycle Disorders and Contraception: 41. Genito-urinary Disorders: 42. Cancer and Palliative Care: 43. Anaemia and Drug-induced Blood Dyscrasias: 44. Rheumatoid Arthritis: 45. Osteoarthritis and Gout: 46. Bone Disorders: 47. Skin Disorders: 48. Wound Management: 49. Drug Therapy in Geriatric Patients: 50. Drug Therapy in Paediatric Patients: 51.Drugs Used in Pregnancy and During Lactation: 52. Critical Care Therapeutics: 53. Recent Advances in Pharmacotherapy: 54. Colds and Influenza: 55. Eye: 56. Oral and Dental: 57. Foot: 58. Ear: 59. Musculoskeletal: 60. Abdominal Pain, Perianal and Perivulval Pruritus: 61. Travel Medicine: 62. Pharmacy Literature and Medicine Information: 63.Medical Writing: 64. Research Methodology: 65. Primary Care Health Services: 66. Community Pharmacy Management: 67. Hospital Pharmacy Services: 68. Formulary Systems: 69. Medicines Regulatory Affairs: 70. Quality Standards in Community Pharmacy Practice

    Out of stock

    £999.99

  • Research Methods for Pharmaceutical Practice and

    Pharmaceutical Press Research Methods for Pharmaceutical Practice and

    5 in stock

    Book SynopsisUsing a scientific approach, this title outlines a thorough process for conducting pharmaceutical practice and policy research and presents a theoretical and practical framework for research methods, supported by applications and examples.Trade Review"Although Research Methods for Pharmaceutical Practice and Policy was designed to be an introductory textbook for graduate students in the social and administrative sciences in pharmacy, this book will be useful to other groups, including faculty and researchers in this area, and professional program students who desire to learn more about this type of research. The book is scholarly in tone and exceptionally well referenced. The book is easy to read and makes extensive use of research that has been conducted in this field." David P. Zgarrick - ScienceDirect, 2011 -- David P. Zgarrick * ScienceDirect *"The editor has assembled a book that will take the reader through the steps of research from the conception of the research question through possible journals for submission...Individuals who are interested in teaching or performing research in the area of pharmacy practice and policy should consider obtaining this book as a resource for their library." Dean L. Arneson, PharmD, PhD, American Journal of Pharmaceutical Education Vol 75 (5), 2011 -- Dean L. Arneson * American Journal of Pharmaceutical Education *Table of Contents1. Scientific Approach to Pharmaceutical Practice and Policy Research 2. Conceptualizing Research 3. Operationalizing Research 4. Measurement Theory and Methods 5. Experimental Designs 6. Non-experimental Research 7. Sampling Methods 8. Systematic Review of Literature 9. Data Collection Methods 10. Survey Design 11. Statistical Analysis 12. Secondary Data Analysis: Administrative Data 13. Secondary Data Analysis: Commercial Data 14. Secondary Data Analysis: National Sample Data 15. Program Evaluation 16. Future of Pharmaceutical Policy Research

    5 in stock

    £36.10

  • Medicines Use Reviews

    Pharmaceutical Press Medicines Use Reviews

    1 in stock

    Book SynopsisMedicines Use Reviews: A practical guide provides evidence-based information, tips and guidance on how to conduct successful Medicines Use Reviews (MURs).Trade Review"I didn't expect Youssef's book to be as good as it is: very clear, covers topic from different points of view, brilliantly written."RLM, Day Lewis Pharmacy, July 2016

    1 in stock

    £25.65

  • Hospital Pharmacy

    Pharmaceutical Press Hospital Pharmacy

    5 in stock

    Book SynopsisHospital Pharmacy outlines the changes in pharmacy practice within the hospital setting and discusses the vast range of services that are provided. Each chapter is devoted to an area of pharmacy practice and discusses its history, current practice and future developments.Trade Review"a book that details the features of pharmacy services within and from hospital-based pharmacies in the United Kingdom...This book certainly provides readers with a solid understanding of the practice of hospital-based pharmacy in the U.K." Patrick McDonnell, Pharm.D. (Temple University School of Pharmacy) -- Patrick J. McDonnellTable of Contents1. Hospital Pharmacy within the NHS 2. Pharmacy in the acute independent sector 3. Purchasing medicines 4. Medicines supply and automation 5. Controlled drugs in hospital pharmacy 6. Technical services 7. Quality assurance 8. Medicines iInformation 9. Clinical pharmacy 10. Pharmacist prescribing 11. Strategic medicines management 12. Risks with medicines 13. Mental health pharmacy 14. Community health services 15. Information technology 16. Research and development 17. Workplace development 18. Consultant pharmacists 19. Managing services

    5 in stock

    £33.25

  • Pharmaceutical Press Handbook of Extemporaneous Preparation

    Out of stock

    Book SynopsisA comprehensive and easy-to-follow guide to good practice in extemporaneous compounding.Trade Review"...this resource offers a real advantage to both the prescriber and the pharmacist in the provision of quality oral liquids...Of particular use and unique to this text is the inclusion of a 'risk assessment' section in each monograph which addresses the clinical and technical risks associated with the extemporaneous preparation of each oral liquid...This book is not only a useful resource, but a valuable addition to the texts available on extemporaneous dispensing for those prescribers wanting quick access to suitable oral liquid alternatives..." Alison Haywood, Senior Lecturer, Griffith University, and Beverley Glass, Professor of Pharmacy, James Cook University Queensland, Australian Prescriber 34(5), October 2011. -- Alison Haywood * Australian Prescriber *Table of ContentsPart A - Standards 1. Glossary 2. Introduction 3. Risk Management 4. Quality Management 5. Personnel & Training 6. Premises & Equipment 7. Documentation 8. Preparation 9. Formulation & Stability 10. Quality Control 11. Complaints, Product Recalls & Adverse Events 12. Procurement & Quality Assessment 13. Audit & Monitoring Part B Extemporaneous Preparation Formulary 14. Introduction 15. Data Collection 16. Risk Assessment 17. Formulary of Extemporaneous Preparation

    Out of stock

    £999.99

  • Pharmaceutical Press Pharmaceutical Compounding and Dispensing

    Out of stock

    Book SynopsisThis is a modern, detailed and practical guide to the theory and practice of extemporaneous compounding and dispensing. Fully revised and updated, this new edition will be an indispensable reference for pharmacy students and practicing pharmacists.Trade Review"The book is well received, since there are few textbooks or reference books available devoted specifically to compounding. The authors should be commended for emphasizing the historical content in tandem with the preparation instruction...the book remains a good resource for anyone interested in compounding" Christine R. Birnie, PhD, American Journal of Pharmaceutical Education 75(1), Feb 2011 -- Christine R. Birnie * American Journal of Pharmaceutical Education *

    Out of stock

    £999.99

  • MCQs in Pharmaceutical Science and Technology

    Pharmaceutical Press MCQs in Pharmaceutical Science and Technology

    Book SynopsisMCQs in Pharmaceutical Science and Technology includes 600 MCQs progressing from basic science through to clinical considerations.

    £31.35

  • Essentials of Pharmaceutical Chemistry

    Pharmaceutical Press Essentials of Pharmaceutical Chemistry

    1 in stock

    Book SynopsisEssentials of Pharmaceutical Chemistry is an introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. It covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules.Trade Review "...Donald Cairns is a well-known educator, mentor, and researcher...this is an excellent resource for pharmacy students taking pharmaceutical chemistry and for individuals who intend to pursue a career in the pharmaceutical industry...Readers will find this as a useful reference." Rahmat M Talukder, Ph.D.,Doody's Notes, May 2012. -- Rahmat M Talukder * Doody's Notes *"This is a great book detailing the basic chemistry of drugs...Throughout the book there are problems that can be worked, and it includes the answers at the end of the book. It is very easy-to-read and has very good graphics to support the discussions. In addition to being a good text, it is a good refresher for those that would like to review this topic."Compounding Today, 27 Jan 2012. * Compounding Today *Table of Contents1. Chemistry of Acids and Bases; 2. Partition Coefficient and Biopharmacy; 3. Physicochemical Properties of Drugs; 4. Stereochemistry; 5. Drug Metabolism; 6. Volumetric Analysis of Drugs; 7. Analytical Spectroscopy; 8. Chromatographic Methods of Analysis; 9. Stability of Drugs and Medicines; 10. Kinetics of Drug Stability; 11. Licensing of Drugs and the British Pharmacopoeia; 12. Medicinal Chemistry - the Science of Rational Drug Design; 13. Answers to Problems

    1 in stock

    £40.85

  • Pharmaceutical Press FASTtrack Pharmacology

    Out of stock

    Book SynopsisProvides a brief account of drug action, as a study or revision aid. The authors have taken a therapeutic area and considered the major classes of drugs, their actions and, to a limited degree, their uses.Trade Review"This book is intended to enhance material covered in traditional pharmacology textbooks...Visuals, algorithms, diagrams, and key points interspersed throughout the book help reinforce and summarize the material. Readers will be able to assess their understanding of the material through self-assessment questions at the conclusion of each chapter...Undergraduate pharmacy students, as well as other healthcare students, will find this a useful guide to help prepare for examinations." Neela A. Bhajandas, PharmD, Doody's Notes, May 2013. -- Neela A. Bhajandas * Doody's Notes *"The book provides good basic knowledge of pharmacology and is well organized, with sections on principles, followed by sections on the drugs used to treat different therapeutic areas...Overall the authors have generally obtained a good balance of core information that is accessible, without it being a textbook in disguise!...Whilst this book is aimed primarily at Pharmacists, I am sure it would also be of value as a revision aid for Medical students...my own daughter who is a 4th year Medical student said she would buy it, an endorsement indeed!" Professor Clive Page, British Journal of Pharmacology, June 2012 -- Professor Clive Page * British Journal of Pharmacology *Table of Contents1. Pharmacodynamics 2. Receptors 3. G-proteins and Their Downstream Signaling Cascades 4. Ion Channels and Transporters 5. Quantitive Pharmacology 6. Autonomic Pharmacology 7. Local Mediators 8. Pharmacokinetics and Drug Metabolism 9. Gastric Pharmacology 10. Lower Gastrointestinal Pharmacology 11. Antiemetics 12. Antiarrhythmics 13. Cardiovascular Drugs 14. Renal and Urinary Pharmacology 15. Antithrombotic Agents 16. Antiobesity Drugs 17. Asthma and Chronic Obstructive Pulmonary Disease 18. Allergy 19. Anxiolytics and Hypnotics 20. Antidepressants 21. Antiepileptic Drugs 22. Antipsychotic Drugs 23. Parkinson's Disease 24. Analgesics 25. Drugs of Abuse 26. General Anaesthetics 27. Neuromuscular Blocking Drugs 28. Thyroid Disorders 29. Diabetes Mellitus 30. Antibacterial Agents 31. Non-bacterial Infections 32. Anticancer Drugs 33. Steroids 34. Oral Contraceptives 35. Immunopharmacology 36. Biopharmaceuticals 37. Variation in Clinical Efficacy

    Out of stock

    £999.99

  • Remington Education Pharmaceutics

    Pharmaceutical Press Remington Education Pharmaceutics

    Book SynopsisRemington Education: Pharmaceutics covers the basic principles of pharmaceutics, from dosage forms to drug delivery and targeting. It addresses all the principles covered in an introductory pharmacy course. As well as offering a summary of key information in pharmaceutics, it offers numerous case studies and MCQs for self assessment.Trade Review"Many chapters include patient counselling tips, which should be helpful for students. Providing examples of marketed products based on the delivery technology discussed in the chapter makes the concept interesting and relevant... The fundamental theoretical and practical aspects of various drug delivery systems that this book presents will help students develop a solid understanding of the subject." Rahmat M. Talukder, PhD, RPh, Doody's Reviews, November 2014. -- Rahmat M Talukder * Doody's Review Service *Table of Contents1. Introduction to dosage form design; 2. Intermolecular forces and the physical and pharmaceutical properties of drugs; 3. Dispersed systems; 4. Properties of solutions and manipulation of solubility; 5. Chemical stability of drugs; 6. Drug travel from dosage form to receptor; 7. Bioavailability, bioequivalence and the Biopharmaceutical Classification System; 8. Parenteral drug delivery; 9. Delivery of biopharmaceuticals and the use of novel carrier systems; 10. Drug delivery to the eye; 11. Drug delivery from the oral cavity; 12. Oral delivery of immediate release dosage forms; 13. Oral delivery of modified release solid dosage forms; 14. Rectal and vaginal drug delivery; 15. Nasal drug delivery; 16. Drug delivery to the lung and from the lung; 17. Drug delivery to the skin; 18. Transdermal dosage forms: drug delivery to the blood stream.

    £31.35

  • FASTtrack Pharmaceutics  Dosage Form and Design

    Pharmaceutical Press FASTtrack Pharmaceutics Dosage Form and Design

    Out of stock

    Book SynopsisThis revision guide for students delivers the essentials of dosage formulation in a concise and easy-to-use format.Table of Contents1. Pharmaceutical solutions for administration to the gastrointestinal tract; 2. Pharmaceutical disperse systems 1: suspensions - general principles and the formulation of suspensions for oral administration; 3. Pharmaceutical disperse systems 2: emulsions and creams; 4. Pharmaceutical disperse systems 3: ointments, pastes, lotions, gels and related formulations; 5. Parenteral formulations; 6. Ocular, nasal and otic dosage forms; 7. Vaginal and rectal dosage forms; 8. Respiratory dosage forms; 9. Solid-dosage forms 1: tablets; 10. Solid-dosage forms 2: capsules; 11. Introduction to pharmaceutical engineering

    Out of stock

    £999.99

  • Pharmaceutical Press FASTtrack Chemistry of Drugs

    Out of stock

    Book SynopsisA revision guide on pharmaceutical and medicinal chemistry. The book covers all aspects of the chemistry of drugs and includes key points, tips, and self-assessment questions to aid in learning.Trade Review"4 stars. This book is a brilliant resource written by two experts in the field of pharmaceutical and medicinal chemistry. It is intended to complement lecture notes and prepare pharmacy undergraduates for their exams. It would also be a useful resource for practising pharmacists, researchers, scientists and all those with an interest in chemical structure and bonding, intermolecular interactions, drug licensing and pharmacopoeia. The text is well written, with a clear, consistent and open layout. There are overviews outlining what the reader should know after completing each section. The text is presented in concise bullet points, with key points, tips and simple diagrams." Oliver McGurk, medical science undergraduate, Nursing Standard 29(9) October 2014 -- Oliver McGurk * Nursing Standard *Table of Contents1. Chemical structure and bonding; 2. Intermolecular interactions; 3. Acids and bases; 4. Stereochemistry; 5. Chemical reaction mechanisms; 6. Chemistry of electrophiles and nucleophiles; 7. Chemistry of aromatic compounds; 8. Chemistry of carbonyl compounds; 9. Chemistry of aromatic heterocyclic compounds; 10. Amino acids, peptides and proteins; 11. Carbohydrates and nucleic acids; 12. Lipids and steroids; 13. Chemical stability of drugs; 14. Drug metabolism; 15. Molecular spectroscopy and pharmaceutical analysis; 16. Drug licensing and pharmacopoeia; Answers to self-assessment

    Out of stock

    £999.99

  • £38.00

  • The Inhibitor Index

    Taylor & Francis Ltd The Inhibitor Index

    1 in stock

    Book SynopsisMetabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a process of interest is functionally linked to a particular enzyme or receptor. From antibiotics to statins, modern medicine relies on the reliability and ease-of-use of enzyme- and receptor-directed inhibitors and antagonists.The Inhibitor Index is a comprehensive, curated compendium of over 7,800 enzyme inhibitors and receptor antagonists, including many toxins, poisons, and metabolic uncouplers. Trade Review"Purich has compiled this handy reference tool listing approximately 7,800 biologically significant molecules that inhibit the action of enzymes or block cellular receptors...The list of targets enables laboratory researchers to choose the most specific and selective inhibitors or blockers for their experiments, and to remain alert to off-target effects. This unique desk reference will be useful for advanced undergraduate students, graduate students, and researchers devising laboratory research in cellular biochemistry and new drug development."-CHOICE, February 2018 Vol. 55 No. 6Table of ContentsNo TOC, it is an alphabetical listing of compounds.

    1 in stock

    £204.25

  • Dermatokinetics of Therapeutic Agents

    Taylor & Francis Inc Dermatokinetics of Therapeutic Agents

    1 in stock

    Book SynopsisNovel drug delivery technologies strive to bypass challenging biological layers to elicit desired pharmacological activity. The skin, one of our key defensive barriers, allows certain topically applied substances and toxins to pass. The dermatokinetics of a drug determines the efficacy of treatment of skin disorders.Presenting the first comprehensive reference on this important area of research, Dermatokinetics of Therapeutic Agents includes a general overview of the theoretical as well as practical aspects of dermatokinetics and addresses the impact of a drug delivery system on the dermatokinetics of drugs. Chapters and illustrations cover introductory aspects and the significance, methods, and models used in dermatokinetic studies of therapeutic agents.Topics include: Theoretical Models for Dermatokinetics of Therapeutic Agents Drug Delivery Approaches to Modulate Dermatokinetics of DrugsTable of ContentsIntroduction to Dermatokinetics. Theoretical Models for Dermatokinetics of Therapeutic Agents. Drug Delivery Approaches to Modulate Dermatokinetics of Drugs. Conventional Methods of Cutaneous Drug Sampling. Cutaneous Microdialysis. Sampling Substrates by Skin Permeablization. Spectroscopic Techniques in Dermatokinetics Studies. Dermatokinetics of Gene Therapeutics. Regulatory Perspective of Dermatokinetic Studies.

    1 in stock

    £185.25

  • Adverse Drug Interactions

    Taylor & Francis Inc Adverse Drug Interactions

    1 in stock

    Book SynopsisAdverse Drug Interactions: A Handbook for Prescribers assists clinicians by providing key information on potential adverse effects that can result from prescribing two or more drugs for simultaneous use. Interactions that are likely to give rise to life-threatening conditions, and which must therefore be completely avoided, are clearly highlighted. Less threatening but nonetheless important interactions necessitating practical measures, such as frequent monitoring and advice to patients, are also discussed.Presented in a user-friendly format, the book is organised by drug class and provides a brief summary of the mechanism underlying a particular interaction, alternative drugs lacking the same reactions that may be considered, and instructions for monitoring patients when adverse effects occur. All interactions listed in the previous edition have been reviewed and updated using the latest information available. The clinical reality of tTrade Review“There is much to commend. There are useful preliminary sections on the complexity of drug–drug interactions and the emerging role of electronic decision support systems… I was particularly pleased to see the inclusion of interactions with herbal and common over-the-counter medications, alcohol, ‘classic’ recreational drugs, vitamins and minerals, and key food groups.”—Daniel Marks, University College London Hospital, London, British Journal of Hospital MedicineTable of ContentsDrugs Acting on the Cardiovascular System. Drugs Acting on the Central Nervous System. Anticancer and Immunomodulating Drugs. Anticoagulants. Antidiabetic Drugs. Other Endocrine Drugs. Analgesics. Musculoskeletal Drugs. Anesthetic Drugs: General. Drugs to Treat Infections. Drugs Acting on the Gastrointestinal Tract. Respiratory Drugs. Metabolic Drugs. Obstetrics and Gynecology. Drugs Used to Treat the Urinary System. Drugs of Abuse. Miscellaneous. Over-the-Counter/Online Drugs, Traditional and Herbal Remedies. Appendices.

    1 in stock

    £63.64

  • Clin-Alert 2000

    Taylor & Francis Inc Clin-Alert 2000

    1 in stock

    Book SynopsisComplete, Authoritative, Unrivaled CollectionClin-Alert, long established as the pre-eminent source of adverse drug reaction/interaction, now brings you Clin-Alert 2000. Presented in a quick reference format, Clin-Alert 2000 allows very easy access by drug class for comparison reports. Pharmacological classes are arranged based on a modified AHFS Therapeutic Classification Code System AND include the addition of a comprehensive section on alternative/herbal medicines.Table of ContentsDrug Classes Include: Alternative Therapies (herbals, supplements). Antihistamines. Anti-infective Agents. Anti-neoplastics. Autonomic Drugs. Blood Formation and Coagulation. Cardiovascular Drugs. CNS Agents (Analgesics, Sedatives, Psychotherapeutics). Dental Agents. Diagnostic Agents. Electrolytic and Water Balance. EENT Preparations. Gastrointestinal Agents. Hormones and Contraceptives. Radioactive Agents. Topical Products. Vaccines. Vitamins. Miscellaneous.

    1 in stock

    £194.75

  • de Gruyter Hunnius Pharmazeutisches Wörterbuch

    3 in stock

    Book Synopsis

    3 in stock

    £89.96

  • 1 in stock

    £9.49

  • Urban & Fischer/Elsevier Die 100 wichtigsten Medikamente für Klinik und Praxis

    3 in stock

    3 in stock

    £24.30

  • Urban & Fischer/Elsevier Arzneimittel in Schwangerschaft und Stillzeit

    2 in stock

    Book Synopsis

    2 in stock

    £78.20

  • Arzneimittelsicherheit - Wunsch und Wirklichkeit

    Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Arzneimittelsicherheit - Wunsch und Wirklichkeit

    1 in stock

    Book SynopsisLaut wissenschaftlicher Studien könnten 30 bis 70 Prozent unerwünschter Arzneimittelwirkungen vermieden werden. Strittig ist, ob die Sicherheitsprobleme ausreichend an Ärzte und Öffentlichkeit kommuniziert werden. Die Beiträge des XVIII. Kölner Symposiums der "Arbeitsgemeinschaft Rechtsanwälte im Medizinrecht" schildern die rechtlichen und ökonomischen Anforderungen u.a. an die Entwicklung neuer Medikamente. Ein Arbeitsbuch für die tägliche Praxis.Table of Contents1.- Probleme der Pharmaindustrie bei der Entwicklung neuer Medikamente.- Arzneimittelsicherheit und der Umgang mit unerwünschten Nebenwirkungen.- Ethik-Kommissionen – ein Beitrag zur Arzneimittelsicherheit?.- 2.- Rechtliche Rahmenbedingungen der Arzneimitteltherapie.- Arzneimittelregress: Bezahlt der Arzt in Zukunft die Medikamente seiner Patienten? Beispiel: „Spezielle Schmerztherapie“.- Arzneimittelregress in der anwaltlichen Haftung.- Die Arzneimittelhaftung nach § 84 AMG n.F. anhand des Beispiels VIOXX ®.- 3.- Neue Aspekte der Arzneimittelhaftung.- Entscheidungen der Gutachterkommission zur Arzneimitteltherapie.- Aufklärungspflicht in der Arzneimitteltherapie aus der Sicht der Gutachterkommission.

    1 in stock

    £38.69

  • Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Allgemeine Chemie: Chemie-Basiswissen I

    Out of stock

    Book SynopsisDer erste Band der Reihe „Chemie-Basiswissen“ vermittelt die allgemeinen Grundlagen der Chemie für Bachelor-Studiengänge sowie für Studierende des höheren Lehramts. Die Autoren präsentieren die am Curriculum orientierte Stoffauswahl in kurzer und übersichtlicher Form und in einem lernfreundlichen Layout. In der 10. Auflage sind die Inhalte noch genauer auf die Bedürfnisse der Studierenden zugeschnitten. Zu der für das Hauptfach Chemie darüber hinaus erforderlichen Chemie der Elemente ist jetzt ein eigener, vierter Band erschienen. Table of ContentsChemische Elemente und chemische Grundgesetze.- Aufbau der Atome.- Periodensystem der Elemente.- Moleküle, chemische Verbindungen, Reaktionsgleichungen und Stöchiometrie.- Chemische Bindung, Bindungsarten.- Komplexverbindungen, Bindungen in Komplexen.- Zustandsformen der Materie (Aggregatszustände).- Mehrstoffsysteme, Lösungen.- Redoxsysteme.- Säure-Base-Systeme.- Energetik chemischer Reaktionen (Grundlagen der Thermodynamik).- Kinetik chemischer Reaktionen.- Chemisches Gleichgewicht (Kinetische Ableitung).

    Out of stock

    £999.99

  • General Pharmacology

    Springer-Verlag Berlin and Heidelberg GmbH & Co. KG General Pharmacology

    1 in stock

    Book SynopsisThe author's general aim has been to survey as wide a field of evidence as possible and this had involved excursions into subjects of which he has little first hand knowledge. This width of range also has necessitated a somewhat arbitrary selection of evidence and has prevented full discussion of any indi- vidual problem. The author trusts that he has not misrepresented anyone's results or opinions, and if this has occurred, he can only plead in excuse the peculiar difficulty of giving a brief and yet accurate account of evidence of such a wide variety. The diagrams reproduced in the article have all been redrawn and in many cases the original figures or diagrams have been modified as, for instance, by recalculating dosage on the logarithmic scale. The original authors therefore have no direct responsibility for the diagrams in their present form. The author desires to thank Messrs Arnold and Co. for permitting the repro- duction of Figs. 9 and 23 from similar figures which appeared in his book "The Mode of Action of Drugs on Cells"; portions of other figures from this book also have been reproduced in modified form. The author also desires to thank Dr. J. M. ROBSON for help in correction of the proofs. Edinburgh, July, 1937. A. J. CLARK. Contents.Table of Contents1: Methods of General Pharmacology.- General Considerations p. 4. — Selection of Material p. 5. — Employment of Physico-chemical Methods p. 5. — The Mathematical Interpretation of Biological Data p. 6. — Favourable Factors in Pharmacological Measurements p. 7. — Curves Relating Exposure to Drugs with Biological Effect p. 7. — Classes of Curves p. 8. — Discussion p. 9.- 2: The Cell as a Physico-chemical System.- The Structure of Protoplasm p. 10. — The Cell Surface p. 12. — Cell Permeability p. 12. — Structure of Plasmatic Membrane p. 14. — Cell Organisation p. 15.- 3: General Characteristics of the Cell-Drug System.- Dimensions of Molecules and Cells p. 17. — The Number of Molecules in Single Cells p. 19. — The Number of Enzyme Molecules per Cell p. 19. — Lethal Doses of Drugs per Cell p. 20. — Effective Doses of Drugs per Cell p. 21. — Minimum Active Doses of Drugs per Organism p. 22. — Minimum Active Dilutions of Drugs p. 22. — Intracellular Administration of Drugs p. 23. — Types of Action of Drugs on Cells p. 25. — Discussion p. 25.- 4: Reactions between Drugs and Active Proteins.- Symplex Compounds p. 26. — Combination of Haemoglobin with Oxygen and Carbon Monoxide p. 27. — Antagonism of Oxygen and Carbon Monoxide p. 29. — Discussion p. 30.- 5: The Action of Drugs on Catalysts and Enzymes.- Poisoning of Inorganic Catalysts p. 31. — General Characters of Enzymes p. 33. — Enzyme Activity p. 34. — General Characters of the Poisoning of Enzymes p. 34. — Diphasic Actions of Enzyme Poisons p. 36. — The Rate of Action of Enzyme Poisons p. 37. — Relation between Concentration of Poison and Inhibitien of Enzyme p. 37. — Discussion p. 40.- 6: Action of Heavy Metals on Enzymes in vitro and in vivo.- Action of Heavy Metals on Saccharase p. 40. — Concentration-action Relations of Heavy Metals and Enzymes p. 42. — The Action of Metals on Living Cells p. 44. — Relation between Metal Concentration and Action on Cells p. 44. — Minimum Lethal Concentrations of Heavy Metals p. 44. — Relative Toxicity of Metals p. 46. — Course of Reaction between Metals and Cells p. 47. — Diphasic Actions of Metals on Cells p. 48. — Discussion p. 49.- 7: Action of Various Enzyme Poisons in vitro and in vivo.- The Action of Dyes on Enzymes p. 50. — Action of Quinine on Enzymes p. 51. — Action of Quinine on Cells p. 52. — Action of Cyanide on Enzymes and Cells p. 52. — Diphasic Actions of Cyanide p. 55. — Phenol Compounds p. 55. — The Action of Narcotics p. 56. — Action of Narcotics on Enzymes p. 56. — Action of Narcotics on Cells p. 59. — Theories of Narcotic Action p. 60. — Discussion p. 61.- 8: Concentration-action Relations I.- (1) Classification of Concentration-action Curves.- Relations Depending on Mass-action p. 63. — All-or-None Effects p. 64.- (2) Concentration-action Relations Attributable to Mass-action Laws.- The Mode of Action of Acetylcholine p. 66. — Amount of Acetylcholine Acting on Cells p. 69. — Individual Variation p. 70. — Site of Action of Acetylcholine p. 70. — Influence of Temperature on Acetylcholine Response p. 72. — Specificity of Acetylcholine Action p. 72. — Possible Nature of Acetylcholine Receptors p. 73. — Acetylcholine Esterase p. 74. — Concentration-action Relations of Adrenaline p. 74. — Dosage of Adrenaline p. 75. — Concentration-action Relations Found with Various Hormones p. 76. — Insulin p. 76. — Thyroxin p. 77. — Posterior Pituitary Principles p. 77. — Sex Hormones p. 77. — Various Alkaloids p. 78. — Nicotine p. 78. — Physostigmine p. 79. — Other Alkaloids p. 79.- 9: Concentration-action Relations II.- (3) Linear Relations; Action of Narcotics.- (4) All-or-None Responses.- Instrumental Errors p. 83. — Distortion by the Cell of some Chemical Relation p. 83. — Obligatory All-or-None effects p. 84. — All-or-None Cellular Responses p. 85. — Concentration-action Curves with Guinea Pig’s Uterus p. 86. — Drugs Producing All-or-None Effects p. 87. — Discussion p. 89.- 10: Quantitative Pharmacology and the Theory of Humoral Transmission.- p. 90. — Quantitative Data p. 91. — Rate of Action p. 92. — Concentration-action Relations p. 93. — Specific Antagonisms p. 95. — Discussion p. 96.- 11: Kinetics of Drug Action.- Sources of Error in Kinetic Measurements.- (1) Kinetics of Reactions in Heterogenous Systems.- (2) Kinetics of Cell Reaction.- Delays in Drug Action Due to Diffusion to Cell Surface p. 98. — Penetration of Cells p. 100. — Delay in Biological Response p. 102.- (3) Maximum Rate of Drug Action.- 12: The Rate of Action of Drugs on Cells.- (1) Curves Relating Time and Graded Action.- The Shapes of Time-action Curves p. 107.- (2) Curves Relating Time and All-or-None Effects.- Kinetics of Protein Precipitation p.110. — Precipitation of Protein by Phenol p. 111.- (3) Time Action Curves as Expressions of Variation.- Calculation of Time-action Curves p. 114. — Time Relations of Toxic Action of Copper on Algae p. 115.- (4) Implications of Monomolecular Theory.- Quantitative Measurements of Drug Uptake p. 118. — Drug Actions as Chain Processes p. 119.- (5) Mortality Curves.- (6) Action of Radiations.- Discussion p. 122.- 13: Time-concentrations Curves.- (1) Form of Curves and Possible Significance.- (2) Time-concentration Curves of Nerve Paralysis.- (3) Time-concentration Curves with Various Drugs.- (4) Time-concentration Relations in Disinfection.- (5) Toxic Vapours.- Deviation of Narcotics p. 139. — Time-concentration Curves of Anaesthetics p. 140. — Time-concentration Curves of Hydrocyanic Acid p. 141. — Irritant Gases p. 141. — Discussion p. 142.- 14: Individual Variation of Response to Drugs.- Methods of Measurement of Individual Variation p. 142. — Skew Variation in Biological Material p. 144. — Normal Equivalent Deviation p. 146. — Errors in Construction of Characteristic Curves p. 148. — Uniformity of Population p. 148. — Errors of Sampling p. 149.- 15: Relation between Various Types of Curves Expressing Response of Cells to Drugs.- (1) Concentration-action Curves as Expressions of Individual Variation.- Virus Infections p. 151. — Discussion p. 153.- (2) Characteristic Curves as Expressions of Chemical Processes.- (3) Correlation between Concentration-action Curves and Characteristic Curves.- Examples of Skewed Characteristic Curves p. 156. — All-or-None Effects p. 161. — Discussion p. 162.- (4) Drug Responses and Individual Variation.- 16: Special Problems Relating to Variation of Populations.- Uniformity of Population p. 165. — Influence of Sex, Age and Weight on Response to Drugs p. 166. — Seasonal Variations in Sensitivity p. 169. — Variation in Human Populations p. 169. — Hypersensitivity and Idiosyncrasy p. 171. — Margin of Safety with Massive Doses p. 173. — Disinfection, etc. p. 175.- 17: Quantitative Aspects of Drug Antagonism and of Drug Synergism.- p. 176. — The antagonism of cyanides by narcotics p. 177. — Selective Antagonisms with Haemoglobin p. 180. — Antagonism in Enzyme Poisoning p. 181. — Acetyl Choline-Atropine Antagonism p. 184. — AdrenalineErgotoxine Antagonism p. 186. — Synergists of Adrenaline p. 187. — Comparison of Antagonisms found with Enzymes and with Hormones p. 188.- 18: Qualitative Aspects of Drug Antagonism.- p. 190. — Antagonism of Adrenaline p. 191. — Chemical Structure of Acetyl Choline Antagonists p. 191. — Acetyl Choline Antagonism in Different Tissues p. 193. — Analysis of Drug Actions by Drug Antagonisms p. 196. — General Theory of Drug Antagonisms p. 198.- 19: Alternative Theories of Drug Action.- Monomolecular Theory p. 199. — The Potential Theory of Drug Action p. 200. — Phasic response of cells p. 201. — Arndt-Schulz Law p. 204. — Drug Responses as Expression of Individual Variation p. 204. — Weber-Fechner Law p. 205. — Discussion p. 205.- 20: Quantitative Aspects of Chemotherapy.- p. 206. — Action of Metallic Compounds p. 207. — Action of Non-metallic Compounds p. 212. — Drug-resistance p. 213. — Discussion p. 214.- 21: Conclusion.- Index of Authors.- Index of Subjects.

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    Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Erzeugung von Krankheitszuständen durch das Experiment: Tumoren II

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    Indiana University Press Pharmacy in Senegal

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    Indiana University Press Pharmacy in Senegal

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    John Wiley & Sons Inc Thermodynamics of Pharmaceutical Systems

    Book SynopsisDesigned for pharmacy students Now updated for its Second Edition, Thermodynamics of Pharmaceutical Systems provides pharmacy students with a much-needed introduction to the mathematical intricacies of thermodynamics in relation to practical laboratory applications. Designed to meet the needs of the contemporary curriculum in pharmacy schools, the text makes these connections clear, emphasizing specific applications to pharmaceutical systems including dosage forms and newer drug delivery systems. Students and practitioners involved in drug discovery, drug delivery, and drug action will benefit from Connors'' and Mecozzi''s authoritative treatment of the fundamentals of thermodynamics as well as their attention to drug molecules and experimental considerations. They will appreciate, as well, the significant revisions to the Second Edition. Expanding the book''s scope and usefulness, the new edition: Explores in greater depth topics most relevantTable of ContentsPREFACE. PREFACE TO THE FIRST EDITION. 0. Review of Mathematics. 0.1. Introduction. 0.2. Dimensions and Units. 0.3. Logarithms and Exponents. 0.4. Algebraic and Graphical Analysis. 0.5. Dealing with Change. 0.6. Statistical Treatment of Data. Problems. I BASIC THERMODYNAMICS. 1. Energy and the First Law of Thermodynamics. 1.1. Fundamental Concepts. 1.2. The First Law of Thermodynamics. 1.3. The Enthalpy. Problems. 2. The Entropy Concept. 2.1. The Entropy Defined. 2.2. The Second Law of Thermodynamics. 2.3. Applications of the Entropy Concept. Problems. 3. The Free Energy. 3.1. Properties of the Free Energy. 3.2. The Chemical Potential. Problems. 4. Equilibrium. 4.1. Conditions for Equilibrium. 4.2. Physical Processes. 4.3. Chemical Equilibrium. Problems. II THERMODYNAMICS OF PHYSICAL PROCESSES. 5. Introduction to Physical Processes. 5.1. Scope. 5.2. Concentration Scales. 5.3. Standard States. Problems. 6. Phase Transformations. 6.1. Pure Substances. 6.2. Multicomponent Systems. Problems. 7. Solutions of Nonelectrolytes. 7.1. Ideal Solutions. 7.2. Nonideal Solutions. 7.3. Partitioning Between Liquid Phases. Problems. 8. Solutions of Electrolytes. 8.1. Coulombic Interaction and Ionic Dissociation. 8.2. Mean Ionic Activity and Activity Coefficient. 8.3. The Debye–Hückel Theory. Problems. 9. Colligative Properties. 9.1. Boiling Point Elevation. 9.2. Freezing Point Depression. 9.3. Osmotic Pressure. 9.4. Isotonicity Calculations. Problems. 10. Solubility. 10.1. Solubility as an Equilibrium Constant. 10.2. The Ideal Solubility. 10.3. Temperature Dependence of the Solubility. 10.4. Solubility of Slightly Soluble Salts. 10.5. Solubilities of Nonelectrolytes: Further Issues. Problems. 11. Surfaces and Interfaces. 11.1. Thermodynamic Properties. 11.2. Adsorption. Problems. III THERMODYNAMICS OF CHEMICAL PROCESSES. 12. Acid–Base Equilibria. 12.1. Acid–Base Theory. 12.2. pH Dependence of Acid–Base Equilibria. 12.3. Calculation of Solution pH. 12.4. Acid–Base Titrations. 12.5. Aqueous Solubility of Weak Acids and Bases. 12.6. Nonaqueous Acid–Base Behavior. 12.7. Acid–Base Structure and Strength. Problems. 13. Electrical Work. 13.1. Introduction. 13.2. Oxidation–Reduction Reactions. 13.3. Electrochemical Cells. 13.4. pH Measurement. 13.5. Ion-Selective Membrane Electrodes. Problems. 14. Noncovalent Binding Equilibria. 14.1. Introduction. 14.2. The Noncovalent Interactions. 14.3. Binding Models. 14.4. Measurement of Binding Constants. 14.5. Applications. Problems. APPENDIXES. Appendix A Physical Constants. Appendix B Kinetic Theory of Gases. Appendix C Extrathermodynamic Relationships. ANSWERS TO PROBLEMS. BIBLIOGRAPHY. INDEX.

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    John Wiley and Sons Ltd Prescribing at a Glance

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    Book SynopsisThe principles of drug therapies are fundamental to medical practitioners in all branches; but are often difficult to get to grips with.Table of ContentsPreface v How to Use Your Textbook vi About the Companion Website ix Part 1 Basic Principles of Prescribing 1 1 Introduction: principles of good prescribing 2 2 Revision: pharmacokinetics 4 3 Using the British National Formulary 6 4 Taking a medication history 8 5 Reviewing current medicines 10 Part 2 Drug Selection 13 6 How to choose a drug 14 7 How to choose frequency 15 8 How to choose a dose 16 9 How to choose route of administration and formulation 18 10 How to choose duration of treatment, defi ne treatment objectives and measure outcomes 20 11 Assessing suitability of treatment regimens for patients 21 12 Worked example 1: Chapters 6–11 22 13 Worked example 2: Chapters 6–11 23 Part 3 Prescribing for Special Groups 25 14 Prescribing in liver disease 26 15 Prescribing in renal disease 28 16 Prescribing in children 30 17 Prescribing in the elderly 32 18 Prescribing in pregnancy and breast feeding 34 Part 4 Logistics of Prescribing 37 19 How to write a drug prescription 38 20 Communicating with patients about medicines 40 21 Therapeutic drug monitoring 42 22 Dealing with adverse drug reactions 44 23 Avoiding drug interactions (drugs, food and alternative medicines) 46 24 Avoiding prescribing errors 48 Part 5 Specific Drug Groups 51 25 Using drugs for the gastrointestinal system 52 26 Using drugs for the cardiovascular system I 54 27 Using drugs for the cardiovascular system II 56 28 Using drugs for the cardiovascular system III 58 29 Using drugs for the respiratory system 60 30 Using drugs for the neurological system I 62 31 Using drugs for the neurological system II 64 32 Using drugs for infection 66 33 Using drugs for the endocrine system I 68 34 Using drugs for the endocrine system II 70 35 How to use drugs for the musculoskeletal system 72 36 Using drugs in haematology and oncology 74 37 Using drugs in anaesthesia 76 38 An approach to common prescribing requests I 78 39 An approach to common prescribing requests II 80 Appendix Cross references to Prescribing Scenarios at a Glance 81 Index 82

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    John Wiley & Sons Inc Green Techniques for Organic Synthesis and

    Book SynopsisAn updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique's features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry.It is divided into 4 parts. 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Long 5.1 History of Green Consumer Cleaning Products 91 5.2 Drivers for Greener Products 94 5.3 Development of Green Cleaning Criteria and Eco-Labeling 98 5.4 Development of Greener Ingredients for Cleaners 102 5.5 The Future of Green Cleaning 111 Acknowledgments 112 References 112 Innovation with Non-Covalent Derivatization 117John C.Warner and Emily Stoler 6.1 Introduction 117 6.2 NCD Overview 118 6.3 Pharmaceutical NCDs 121 6.4 Environmental and Green Chemistry Benefits 123 References 123 Part II Green Catalysts 131 Catalytic C-H Bond Cleavage for Heterocyclic Compounds 133Zhanxiang Liu and Yuhong Zhang 7.1 Introduction 133 7.2 Synthesis of Nitrogen Heterocycles 133 7.3 Synthesis of Oxygen-Containing Heterocycles 144 7.4 Synthesis of Sulfur-Containing Heterocycles 148 7.5 Medium-Sized Heterocyclic Compounds 150 7.6 Conclusion 152 References 152 Biocatalysis 161James Lalonde 8.1 Introduction 161 8.2 Enzymes for Biocatalysis 162 8.3 Advances in Enzyme Engineering and Directed Evolution 164 8.4 Biocatalytic Synthesis of Pharmaceuticals: Case Studies of Highly Efficient Pharmaceutical Syntheses 165 8.5 Summary and Future Outlook 178 References 180 Practical Asymmetric Organocatalysis 185Wen-Zhao Zhang, Samik Nanda, and Sanzhong Luo 9.1 Introduction 185 9.2 Aminocatalysis 185 9.3 Brønsted Acid Catalysis 191 9.4 Brønsted Base Catalysis 193 9.5 Hydrogen-Bonding Catalysis 197 9.6 Phase-Transfer Catalysis 202 9.7 Lewis Acid, Lewis Base, and N-Heterocyclic Carbene Catalysis 204 9.8 Large-Scale Reaction (>100-Gram Reaction) 207 9.9 Conclusion 209 References 209 Fluorous Catalysis 219L´aszl´o T. Mika and Istv´an T. Horv´ath 10.1 Introduction and the Principles of Fluorous Catalysis 219 10.2 Ligands for Fluorous Transition Metal Catalysts 224 10.3 Synthetic Application of Fluorous Catalysis 225 10.4 Fluorous Organocatalysis 256 10.5 Other Applications of Fluorous Catalysis 259 References 259 Solid-Supported Catalysis 269Sukanta Bhattacharyya and Basudeb Basu 11.1 Introduction 269 11.2 Immobilized Palladium Catalysts 270 11.3 Immobilized Rhodium Catalysts 276 11.4 Immobilized Ruthenium Catalysts 279 11.5 Other Immobilized Catalysts 284 11.6 Conclusions 286 References 287 Asymmetric Organocatalysis in Aqueous Media 291Kartick C. Bhowmick and Tanmoy Chanda 12.1 Introduction 291 12.2 Carbon-Carbon Bond-Formation Reactions 292 12.3 Reactions Other than C-C Bond Formation 313 12.4 Conclusion 314 References 314 Part III Green Synthetic Techniques 325 Solvent-Free Synthesis 327Kendra Leahy Denlinger and JamesMack 13.1 Introduction 327 13.2 Ball Milling 328 References 339 Ultrasonic Reactions 343Rodrigo Cella and H´elio A. Stefani 14.1 Introduction 343 14.2 How Does CavitationWork? 343 14.3 Aldol/Condensation Reactions 345 14.4 1,4-Addition 351 14.5 Heterocycles Synthesis 353 14.6 Coupling Reactions 356 14.7 Wittig Reaction 361 14.8 Diels-Alder Reaction 362 14.9 Miscellaneous 365 14.10 Conclusions 366 References 366 Photochemical Synthesis 373Stefano Protti,Maurizio Fagnoni, and Angelo Albini 15.1 Introduction 373 15.2 Synthesis and Rearrangement of Open-Chain Compounds 376 15.3 Synthesis of Three- and Four-Membered Rings 382 15.4 Synthesis of Five-, Six- (and Larger)-Membered Rings 391 15.5 Oxygenation and Oxidation 398 15.6 Conclusions 400 Acknowledgments 401 References 401 Pot Economy Synthesis 407Wenbin Yi, Xin Zeng, and Song Gao 16.1 Introduction 407 16.2 Multicomponent Reactions 407 16.3 One-Pot and Multi-Step Reactions 415 16.4 One-Pot Asymmetric Synthesis 424 16.5 Outlook 434 References 434 Microwave-Assisted Organic Synthesis: Overview of Recent Applications 441Nandini Sharma, Upendra K. Sharma, and Erik V. Van der Eycken 17.1 Introduction 441 17.2 C-H Functionalization 449 17.3 Insertion Reactions 452 17.4 Reduction 453 17.5 Synthesis of Peptides and Related Fine Chemicals 455 17.6 Newer Developments 459 17.7 Summary 461 References 461 Solid-Supported Synthesis 469Indrajeet J. Barve and Chung-Ming Sun Abbreviations 469 18.1 Introduction 471 18.2 Techniques of Solid-Phase Supported Synthesis 472 18.3 Solid-Phase Supported Heterocyclic Chemistry 476 18.4 Solid-Supported Synthesis of Natural Products 486 18.5 Solid-Supported Organometallic Chemistry 491 18.6 Solid-Phase Synthesis of Peptides 493 18.7 Solid-Phase Supported Stereoselective Synthesis 494 18.8 Interdisciplinary Solid-Supported Synthesis 499 References 505 Light Fluorous Synthesis 509Wei Zhang 19.1 Introduction 509 19.2 “Heavy” Versus “Light” Fluorous Chemistry 509 19.3 The Green Chemistry Aspects of Fluorous Synthesis 510 19.4 Fluorous Techniques for Discovery Chemistry 511 19.5 Conclusions 533 References 533 Part IV Green Techniques and Strategies in the Pharmaceutical Industry 539 Ionic Liquids in Pharmaceutical Industry 541Julia L. Shamshina, Paula Berton, HuiWang, Xiaosi Zhou, Gabriela Gurau, and Robin D. Rogers Abbreviations 541 20.1 Introduction 543 20.2 Finding the Right Role for ILs in the Pharmaceutical Industry 544 20.3 Conclusions and Prospects 567 References 568 Green Technologies and Approaches in theManufacture of Biologics 579Sa V. Ho and Kristi L. Budzinski 21.1 Introduction 579 21.2 Characteristics of Biologics 580 21.3 Manufacture of Therapeutic Biologics 581 21.4 Environmental Metrics Development and Impact Analysis 587 21.5 Some Future Directions 592 21.6 Conclusions 594 Acknowledgments 594 References 594 Benchmarking Green Chemistry Adoption by “Big Pharma”and Generics Manufacturers 601Vesela R. Veleva and BerkeleyW. Cue 22.1 Introduction 601 22.2 Literature Review 602 22.3 Pharmaceutical Industry Overview and Green Chemistry Drivers 604 22.4 Benchmarking Industry Adoption of Green Chemistry 607 22.5 Results and Discussion 610 22.6 Conclusion 616 References 616 Green Process Chemistry in the Pharmaceutical Industry: Case Studies Update 621Joseph M. Fortunak, Ji Zhang, Frederick E. Nytko III, and Tiffany N. Ellison 23.1 Introduction 621 23.2 Pharmaceutical Patents Driving Innovation 622 23.3 A Caution About Drug Manufacturing Costs 623 23.4 Process Evolution by Multiple Route Discovery Efforts—Dolutegravir 624 23.5 The Impact of Competition on Process Evolution—Tenofovir Disoproxil Fumarate 628 23.6 Simeprevir (Olysio/Sovriad) and Analogues: Chiral Phase-Transfer Catalyst-Promoted Optical Alpha-Amino Acid Synthesis: A Metal-free Process 633 23.7 Vaniprevir (MK 7009), Simeprevir (TMC435), and Danoprevir: Ring-Closing Metathesis (RCM) for Macrocyclic Lactam Synthesis: Now a Commercial Reality 635 23.8 Daclatasvir (BMS-790052, Daklinza), and Ledipasvir (GS-5885): Palladium Catalyzed Cross-Coupling for Greening a Process 638 23.9 Sitagliptin (Januvia) and Ponatinib (Iclusig): Greening the Process by Telescoping Multiple Steps Together 639 23.10 Febuxostat (Uloric): Greening the Process via Metal Catalyzed C-H Activation: A Prospect 641 23.11 Conclusions 644 References 644 Greener Pharmaceutical Science Through Collaboration: The ACS GCI Pharmaceutical Roundtable 649Julie B. Manley andMichael E. Kopach 24.1 Introduction 649 24.2 Establishing Pre-Competitive Collaborations 650 24.3 Informing and Influencing the Research Agenda 654 24.4 Developing Tools 661 24.5 Educating Leaders 666 24.6 Collaborating Globally 668 24.7 Future Opportunities 669 24.8 Success Factors 671 References 673 Index 675

    £143.06

  • American Pharmacists Association The Pharmacist in Public Health: Education,

    Out of stock

    Book SynopsisWritten and edited by pharmacists for pharmacists, The Pharmacist in Public Health: Education, Applications, and Opportunities integrates public health concepts into pharmacy practice and empowers pharmacists and student pharmacists to become involved in public health. The three pharmacist editors and more than 50 contributing authors with backgrounds in pharmacy or public health explore pharmacy’s important role in public health, opportunities and challenges for pharmacists, and the need for student pharmacists’ education and involvement. The 22 peer-reviewed chapters document pharmacists’ current public health efforts and highlight the need for pharmacist involvement and expertise to resolve public health issues locally, nationally, and globally. Thoroughly referenced, containing many examples, figures, and practitioner profiles, the book is a resource for practicing pharmacists, student pharmacists, and other professionals in the public health community. Key Features: Chapters 1 through 4 review pharmacists’ practice and education in public health, provide a history and overview of both professions, and trace pharmacists’ practice in the United States Public Health Service. Chapters 5 through 17 describe pharmacy practice roles in public health and address why pharmacists need to be involved. These chapters feature profiles of public health pharmacists and practical recommendations for furthering pharmacists’ involvement and contributions via ACT (“Actions for Change Today”). Chapters 18 and 19 focus on expanding pharmacists’ role in public health through continuing professional development and interprofessional health initiatives. Chapters 20 through 22 are dedicated to promoting and applying public health topics in student pharmacists’ educational and professional activities. The chapters include examples of students’ community outreach and local and global service initiatives to improve public health.Table of Contents Foreword Preface Contributing Authors Reviewers Section One 1. Pharmacists in Public Health 2. Introduction to the History and Profession of American Pharmacy 3. Pharmacist Perspective on the History and Profession of Public Health 4. Development and Mission of Pharmacy in the U.S. Public Health Service Section Two 5. Medication Therapy Management: Improving Public Health 6. Medication Safety: Improving Public Health 7. Improving Medication Use in Older Adults 8. Health Behavior Theories and Models: Frameworks for Health Promotion and Education Programs 9. Primary Prevention: Pharmacist-Delivered Immunization Services 10. Global Health: Expanding the Sphere of Pharmacists’ Influence 11. Emergency Preparedness and Pharmacist Response 12. Ethical and Legal Issues Pertinent to Public Health Pharmacy 13. Strategies for Identifying Health Disparities and Improving Cultural Competence 14. Strategies for Improving Health Literacy and Patient Outcomes 15. Substance Abuse: Prevention and Intervention 16. Correctional Pharmacy: Prisons and Public Health 17. Rural Health and Telepharmacy: Public Health Challenges and Opportunities Section Three 18. Continuing Professional Development for Pharmacists in Public Health 19. Interprofessional Initiatives for Pharmacists in Public Health Section Four 20. Strategies and Resources for Teaching Public Health

    Out of stock

    £63.00

  • How to Conduct a Comprehensive Medication Review: A Guidebook for Pharmacists

    American Pharmacists Association How to Conduct a Comprehensive Medication Review: A Guidebook for Pharmacists

    1 in stock

    Book SynopsisThis guidebook will help pharmacists transition from the preparation to the implementation phase. It provides a step-wise approach to conducting an MTM encounter. Components of this guidebook expand upon key concepts in the 2012 APhA publication, How to Start an MTM Practice: A Guidebook for Pharmacists, which focuses on the operational and business aspects of starting an MTM service. This guidebook assists pharmacists with the next steps, emphasizing the patient encounter, including patient recruitment and the comprehensive medication review. Following the process detailed will help to ensure a standardized, comprehensive approach to the delivery of MTM services.Key Features MTM Encounter Checklist Steps in patient recruitment Preparing for and conducting a comprehensive medication review Assessing and documenting the MTM encounter 10 appendices offer wealth of practical resources including sample MTM recruitment letter, marketing flyer, telephone script, and patient data collection form Table of Contents Acknowledgements About This Guidebook Medication Therapy Management (MTM) Encounter Checklist 1. Introduction to the MTM Process 2. Patient Recruitment and Scheduling 3. Preparing for the Comprehensive Medication Review (CMR) 4. The CMR Encounter 5. Assessing Medication-Related Problems 6. Documenting the CMR Encounter and Plan 7. Billing and Compensation 8. Evaluating the Impact of the MTM Service References Appendix A. Sample MTM Recruitment Letter Appendix B. MTM Marketing Flyer Template Appendix C. Get Your Medication Check-up Brochure Appendix D. MTM Promotional Brochure Appendix E. Sample Telephone Script for MTM Recruitment of a Patient Not Affiliated with the Pharmacy Appendix F. Patient Data Collection Form, Version 1 Appendix G. Patient Data Collection Form, Version 2 Appendix H. Sample Authorization for Release of Medical Information Appendix I. CMS Standardized Format for the Medication Action Plan and Personal Medication List Appendix J. Sample Superbill

    1 in stock

    £20.85

  • American Pharmacists Association How to Implement the Pharmacists’ Patient Care Process

    1 in stock

    Book SynopsisIn pharmacy, there is enormous variability in the approach to and delivery ofpatient care by pharmacists. In contrast, other health care fields have uniformlyeducated their respective professionals on a consistent, systematic process ofcare.This publication introduces the Pharmacists’ Patient Care Process, which wasadopted in May 2014 by the Joint Commission of Pharmacy Practitioners(JCPP), a group of 11 national pharmacy organizations. The goal is to helppharmacists understand the components of the standard patient care processand apply the process to patients in all pharmacy practice settings.Six sample case studies set in different patient care settings enable the readerto practice applying the patient care process. Additional activities enablepharmacists to evaluate existing patient care services, develop strategies forcontinuous quality improvement, and create an implementation plan for theirpractice.Key Feature: A thorough, yet concise, introduction to the Pharmacists’ Patient Care Process, which JCPP developed and adopted in May 2014 A detailed explanation of each of the steps in the process (collect, assess, plan, implement, follow up) Designed as a workbook for use by pharmacists in all practice settings and by pharmacy school instructors as part of their college’s curriculum 6 real-world case studies set in different patient care settings that help the reader practice using the patient care process Exercises that help the user implement strategies for applying the patient care process to existing patient care services Appendices that include case study answer keys and a reprint of the JCPP Pharmacists’ Patient Care Process Table of Contents Preface Contributors Section I. Background Introduction The Foundational Tenets of the Pharmacists’ Patient Care Process Understanding the Pharmacists’ Process of Care Section II. Steps in the Process Collect Assess Plan Implement Follow-up: Monitor and Evaluate Section III. Applying and Implementing the Process Activity 1: Apply the Process to Patient Case Studies Activity 2: Evaluate Existing Services, Develop Strategies, and Implement the Process Activity 3: Advocate, Educate, and Promote Activity 4: Use Continuous Quality Improvement Conclusion References Appendices Appendix A: JCPP Pharmacists’ Patient Care Process Appendix B: Case Studies Patient Data Appendix C: Case Studies Answer Keys

    1 in stock

    £27.86

  • Complete Math Review for the Pharmacy Technician Fifth Edition

    American Pharmacists Association Complete Math Review for the Pharmacy Technician Fifth Edition

    10 in stock

    Book SynopsisComplete Math Review for the Pharmacy Technician, Fifth Edition, offers a friendly, intuitive, self-instructional approach to the lifelong understanding of pharmacy calculations. Filled with real-world practice problems and the author’s good humor and encouragement, the book is a unique training resource, whether for the classroom, the national Pharmacy Technician Certification Examination, or the pharmacy practice setting. KEY FEATURES: 100 all-new test questions aid technicians in fine-tuning their skills and preparing for any standardized exam. Every topic related to pharmacy calculations that a pharmacy technician needs to know is thoroughly covered. More than 850 practice problems are spread throughout its 13 chapters, with answer key/solutions in the back. The PI Challenge is included—with more than 75 questions challenging the reader’s ability to interpret information taken directly from actual pharmaceutical product package inserts. A chapter titled Medication Errors and Clinical Challenges tests readers ability to recognize medication calculation errors sometimes made by nurses, pharmacists, and physicians. The book now concludes with 201 questions in Post-Test I and Post Test II, with each question reflecting a real-world problem a technician might encounter in pharmacy practice. A friendly, humorous writing style and amusing illustrations ease the learning process for even readers with math phobia.

    10 in stock

    £51.30

  • Handbook of Nonprescription Drugs: An Interactive

    American Pharmacists Association Handbook of Nonprescription Drugs: An Interactive

    Out of stock

    Book SynopsisWritten and peer reviewed by experts in practice and academia, the 20th edition of the Handbook of Nonprescription Drugs: An Interactive Approach to Self-Care is an authoritative resource for students and for health care providers who counsel and care for patients undertaking self-treatment—nonprescription drugs, nutritional supplements, medical foods, nondrug and preventive measures, and complementary therapies. Its goal is to develop the knowledge and problem-solving skills needed to assess a patient’s health status and current practice of self-treatment, to determine whether self-care is necessary or appropriate, and, if appropriate, to recommend safe and effective self-care measures. KEY FEATURES: Enhanced content in all chapters from the previous edition with up-to-date information beneficial to all health care providers and students. Updates to the universal objectives to complement the content in the chapters focused on medical disorders. Abstracts for each online chapter providing concise introductory material focused on key features of each chapter. Up-to-date content on nonprescription medications including indications, dosages, interactions, current evidence, medical conditions and prescription to nonprescription reclassifications. Quick-reference tools such as treatment algorithms (including exclusions for self-treatment), drug product tables, patient education sidebars, and product administration illustrations.

    Out of stock

    £186.30

  • Essential Spanish for Pharmacy

    American Pharmacists Association Essential Spanish for Pharmacy

    1 in stock

    Book SynopsisEssential Spanish for Pharmacy, Fourth Edition is intended to be a supplemental quick reference to assist pharmacy professionals in interacting with Spanish-speaking patients. This book includes phrases, keywords, questionnaires, and pictograms to guide a Spanish-based conversation with a patient. It is best used by someone who has a basic understanding of the language and needs more guidance for pharmacy and medical-specific vocabulary. This book also includes basic phases for anyone to make a patient feel welcome with the additional use of a trained interpreter and other resources available.

    1 in stock

    £19.90

  • The Pharmacist Career Journey: Planning for

    American Pharmacists Association The Pharmacist Career Journey: Planning for

    1 in stock

    Book SynopsisAs pharmacists at different phases in our careers, we believe that a focus on and commitment to career planning is important in all phases of a pharmacist's career. We also believe that a refocus on one's career, especially during a period of career discontentment and/or unhappiness, can provide new perspectives, plans, and ideas that can contribute to career enhancement, repurpose, or change. The authors of this book aim to provide resources and actionable planning steps for pharmacists throughout their career journey. Divided into three sections, this book includes information on planning for your career, planning for the progression of your career, and planning for the maximization of your career.KEY FEATURES: Each chapter presents key takeaways, questions and reflections, and exercises designed to reinforce information. Interviews with pharmacists from diverse practice settings offer a multitude of careerplanning perspectives. Emphasis on aspects pertaining to the whole person and work-life integration.

    1 in stock

    £36.86

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