Pharmaceutical chemistry and technology Books
Pan Stanford Publishing Pte Ltd Dendrimer-Based Nanomedicine
Book SynopsisIn recent decades, dendrimers — free-shaped synthetic macromolecules — have garnered a great deal of scientific interest because of their unique molecular nanostructure. Used in a variety of scientific applications, dendrimers are now widely regarded as a safer, more precise and more effective way to practice medicine.This book compiles and details cutting-edge research in science and medicine from the interdisciplinary team of the Michigan Nanotechnology Institute for Medicine and Biological Sciences, which is currently revolutionizing drug delivery techniques through the development of engineered nanodevices. Edited by Istvan J. Majoros and James R. Baker Jr, two prominent nanotechnology researchers, this book will appeal to anyone involved in nanotechnology, macromolecular science, cancer therapy or drug delivery research. Trade Review"The authors' approach to fill in a little history with futuristic perspective will be a delight to all readers interested in the field. A must read."—Prof. George R. Newkome, The University of Akron, USATable of ContentsTargeted Drug Delivery in General, New Technology in Medicine. General Carriers for Drug Delivery. Poly(amidoamine) Dendrimer Synthesis and Characterization. Optical and Biophotonic Applications of Dendrimer Conjugate. Dendrimer Conjugates for Cancer Treatment. Biological Application of PAMAM Dendrimer Nanodevices in vitro and in vivo. Dendrimer-based Targeted Apoptosis Sensors for Medical Application. MRI Using Targeted Dendrimer Contrast Agents. Nanoparticle — Membrane Interactions: Mechanism for Enhanced Permeability. Computer Simulations of Dendrimers. Dendrimer-Entrapped and Dendrimer-Stabilized Metal Nanoparticles for Biomedical Applications.
£153.00
Pan Stanford Publishing Pte Ltd Bio-Inspired Regenerative Medicine: Materials,
Book SynopsisThis book presents a wide and interdisciplinary overview of the current state of the art in the development of biomimetic materials for tissue regeneration on the basis of relevant and high-impact clinical needs. It specifically emphasizes the regeneration of bone, cartilage, and osteochondral tissues as well as soft tissues such as nerves, heart, and endocrine organs. It brings together contributions from materials scientists, biologists, and surgeons with globally recognized experience in the field of regenerative medicine.The aim of the book is to highlight the relevance of biomimetics as an elective approach for the development of new scaffolds that can direct regenerative cascade by means of chemico-physical and topological nano-cues presented to cells and biologic tissues. Particularly, the book refers to emerging concepts in synthesis processes and scaffolds inspired by nature as well as to novel approaches for smart functionalization such as the use of magnetic signaling.Trade Review"This well-written book is essential reading for professionals and students from materials science, materials engineering, biology, or medicine who wish to know the state of the art on biomimetic-inspired materials for surgical applications. All fields are clearly presented, from powder synthesis to scaffold processing, tissue engineering, interaction between biomaterials and living cells, and biomechanical behavior. It is a good reference point for the foreseeable future."—Prof. Anne Leriche, University of Valenciennes, FranceTable of ContentsBio-Inspired Nanomaterials and Nano-Bio-Magnetism in Regenerative Medicine. Nano-Apatites. Biomorphic Scaffolds. Nanocomposites for Bone and Osteochondral Regeneration. Nerve Regeneration. Heart Regeneration. Triggering Cell-Biomaterial Interaction. Clinical Perspective of Bone Regeneration in Orthopaedics and Spine Surgery. Clinical Aspects Related to Osteochondral Regeneration. Organomorphic Approach to Bio-Artificial Endocrine Organs.
£99.00
Pan Stanford Publishing Pte Ltd Drug Delivery Across Physiological Barriers
Book SynopsisTransport of pharmaceutical agents in the body is paramount to therapeutic efficacy. Advances in the past decades have rendered a remarkable improvement of drug delivery strategies, which has helped to increase the bioavailability of therapeutic agents by protecting them from degradation, targeting them to diseased sites, and controlling their circulation time and release rate. Additionally, for most therapeutics, reaching the targets of action require penetration across tissues and/or entry within cells. The design of strategies to control the transport of therapeutic compounds through these physiological barriers has become an imperative and a challenging need in the quest for better therapeutics. This book provides an overview of the current advances in this field, including considerations on the biological regulation and natural mechanisms overcoming these barriers, as well as drug delivery strategies facilitating the transport of drugs and their carriers at the tissue, cell, and subcellular levels. Trade Review"This book combines a thorough overview of the barriers encountered and strategies employed to increase the delivery of therapeutics. It also provides a critical assessment of the merits and limitations of delivery approaches. Overall, this is a concentrate of the most recent scientific discoveries written by highly recognized authors in the field. It is an excellent reference for both students and seasoned scientists."—Dr. Mohamed ElSayed, University of Michigan, USA"Drug delivery across physiological barriers is a historic and challenging problem. This compelling book addresses this topic thoroughly, with detailed chapters ranging from descriptions of the composition of physiological barriers, through barrier-penetrating drug delivery strategies to how drugs are trafficked once inside cells. A must-have addition to any pharmaceutical scientist’s technical library." —Dr. John D. Higgins, Merck & Co., USA"Drug Delivery Across Physiological Barriers is a fundamental book in nanomedicine, particularly for those who start in the field of designing therapeutic strategies based on nano-drug delivery systems. It addresses the challenging anatomical and pathological barriers of the epithelia, endothelia, extracellular matrix, and cell endocytic pathways. It shows that a thorough understanding of the stepwise processing to which nanostructures are exposed throughout the body and intracellularly is a critical tool for a wise design of nanomedicines." —Dr. Eder L. Romero, National University of Quilmes, ArgentinaTable of ContentsIntroduction. Physiological Barriers Controlling Penetration and Transport of Substances in the Body. Structure and function of epithelial and endothelial barriers. The plasma membrane as a semipermeable barrier. Biology and regulation of protein sorting and vesicular transport. Pathogens and intracellular transport. Strategies for Drug Penetration across Tissue Compartments. Drug transport across the skin. Mucosal barriers. Transport of therapeutics across the gastrointestinal epithelium. Crossing the endothelial barrier. Nanoparticle-based drug delivery to solid tumors. Drug Transport into Cells and Subsequent Intracellular Trafficking. Membrane lipids and drug transport. Drug delivery systems that fuse with the plasmalemma. Endocytosis and the endolysosomal route in drug delivery. Endo-lysosomal escape. Intracellular transport to the mitochondria and other organelles.
£99.00
Pan Stanford Publishing Pte Ltd Tuning Innovation with Biotechnology
Book SynopsisThis book deals with evolving intelligence systems and their use in immune algorithm (IM), particle swarm optimization (PSO), bacterial foraging (BF), and hybrid intelligent system to improve plants, robots, etc. It discusses the motivation behind research on and background of evolving intelligence systems and illustrates IM-based approach for parameter estimation required for designing an intelligent system. It approaches optimal intelligent tuning using a hybrid genetic algorithm–particle swarm optimization (GA-PSO) and illustrates hybrid GA-PSO for intelligent tuning of vector system. Table of ContentsBackground. Immune Network–Based Parameter Estimation. Intelligent PID Controller Tuning Using a Hybrid GA-PSO Approach. GA-PSO-Based PI Controller Tuning for Indirect Vector Control of Three-Phase Induction Motor. Novel Hybrid System Based on GA and Bacteria Foraging. Conclusion.
£85.50
Pan Stanford Publishing Pte Ltd Embedding New Technologies into Society: A
Book SynopsisThe embedding of any new technologies in society is challenging. The evolving state of the scientific art, often-unquantifiable risks and ill-defined developmental trajectories have the potential to hinder innovation and/or the commercial success of a technology. The are, however, a number of tools that can now be utilized by stakeholders to bridge the chasm that exists between the science and innovation dimensions on the one hand, and the societal dimensions on the other. This edited volume will draw together leading researchers from the domains of law, philosophy, political science, public administration and the natural sciences in order to demonstrate how tools such as, for example, constructive technology assessment, regulatory governance and societal scenarios, may be employed by stakeholders to assist in successfully embedding new technologies into society. This volume will focus primarily on the embedding of two emergent and emerging technologies: nanotechnologies and synthetic biology. Government, industry and the epistemic community continue to struggle with how best to balance the promised benefits of an emerging technology with concerns about its potential impacts. There is a growing body of literature that has examined these challenges from various cultural, scientific and jurisdictional dimensions. There is, however, much work that still needs to be done; this includes articulating the successes and failures of attempts to the societal embedding of technologies and their associated products. This edited volume is significant and timely, as unlike other books currently on the market, it shall draw from real work experiences and experiments designed anticipate the societal embedding of emerging technologies. This empirical work shall be supported by robust theoretical underpinnings.Table of ContentsIntroduction - Foxes become hedgehogs. Reflexive co-evolution and governance patterns. Governance approaches for emerging technologies. Society as a laboratory to experiment with new technologies. Care and technoscience: re-embedding the future of innovation. Division of moral labour as an element in the governance of emerging technologies. Ethical reflexivity as capacity building: supportive tools and approaches. The demand side of innovation governance: Demand articulation processes in the case of nano-based sensor technologies. Evolving Patterns of Governance of and by Expectations. The Graphene Hype Wave. Transnational challenges of governing new technologies: The case of nanotechnology. Co-Regulation of Nanomaterials: On Collaborative Business Association Activities directed at Contributing to Occupational Health and Safety. The ‘Metamorphosis’ of the drone: the governance challenges of drone technology in border surveillance. On the disruptive potential of 3D printing. Modifying Materials, Mosquitoes and Measures: The Regulation of Nanotechnologies and Synthetic Biology. Conclusions.
£60.79
Pan Stanford Publishing Pte Ltd Capillary Electrophoresis: Trends and
Book SynopsisCapillary electrophoresis (CE) has become an established method with widespread recognition as an analytical technique of choice in numerous analytical laboratories, including industrial and academic sectors. Pharmaceutical and biochemical research and quality control are the most important CE applications. This book provides a comparative assessment of related techniques on mode selection, method development, detection, and quantitative analysis and estimation of pharmacokinetic parameters and broadens the understanding of modern CE applications, developments, and prospects. It introduces the fundamentals of CE and clearly outlines the procedures used to mitigate several barriers, such as detection limits, signal detection, changing capillary environment, resolution separation of analytes, and hyphenation of mass spectrometry with CE, for a range of analytical problems. Each chapter outlines a specific electrophoretic variant with detailed instructions and some standard operating procedures. In this respect, the book meets its desired goal of rendering assistance to lovers of electrophoresis.Trade Review"Decades after its introduction, capillary electrophoresis has evolved into a mature technique, especially in the field of pharmaceutical analysis. This book focuses on a number of fields in which this separation technique has proven its unique usefulness, such as chiral separations and the analysis of protein biopharmaceuticals. It highlights the current state of the art and offers high-quality general chapters and overviews as well as topical chapters. Recommended reading for all those involved in pharmaceutical analysis, albeit academically or industrially!"—Prof. Ann Van Schepdael, University of Leuven, BelgiumTable of ContentsCapillary Electrophoresis: A Versatile Technique in Pharmaceutical Analysis. Recent Applications of Chiral Capillary Electrophoresis in Pharmaceutical Analysis. A Mini-Review on Enantiomeric Separation of Ofloxacin using Capillary Electrophoresis: Pharmaceutical Applications. Nano-Stationary Phases for Capillary Electrophoresis Techniques. Capillary Electrophoresis Coupled to Mass Spectrometry for Enantiomeric Drugs Analysis. Enantioselective Drug–Plasma Protein-Binding Studies by Capillary Electrophoresis. Clinical Use of Capillary Zone Electrophoresis: New Insights into Parkinson’s Disease. Electrophoretically Mediated Microanalysis for Evaluation of Enantioselective Drug Metabolism. Capillary Electrophoresis for the Quality Control of Intact Therapeutic Monoclonal Antibodies. Molecular Simulation of Chiral Selector–Enantiomer Interactions through Docking: Antimalarial Drugs as Case Study.
£85.50
Jenny Stanford Publishing Nanotechnology and Drug Delivery: Principles and
Book SynopsisThis book presents an overview of the rapidly developing field of nanotechnology applications in drug delivery systems and covers a variety of technologies and materials that help in achieving vast variation in the particle size needed in technology and drug delivery-based research. It discusses nanotechnology’s use in healthcare for the development of target-specific drug therapy and smart field systems and in the pharmaceutical industry to improve the quality, efficacy, and shelf life of medicines. Bringing together principles, theory, practice, and applications of nanotechnology, the book is a useful resource for chemists, physicists, biomedical researchers, engineers, advanced undergraduate and graduate-level students in nanotechnology, researchers in pharmaceutical sciences, chemistry, biology, biotechnology engineering, and general readers in nanotechnology.Table of Contents1. Basics of Nanotechnology and Drug Delivery Systems 2. Regulatory Barriers to the Marketing Authorization of Nanodrug Delivery System 3. Nanodrug Delivery System for Brain Targeting 4. Reconnoitring the Beneficial Role of Nanodrug Delivery System in Treating Cardiovascular Disorders 5. Smart Targeted Novel Nanocarriers-Based Treatment of Arthritis 6. Novel Drug Delivery System for Ocular Target 7. Nanotechnology-Based Drug Delivery Systems for the Treatment of Pulmonary Diseases 8. The Potential of Nanotechnology in Transdermal Drug Delivery Systems 9. Novel Drug Delivery Systems for Infection Treatment 10. Novel Drug Delivery System Approach in Cancer Treatment 11. Nano-Drug Delivery Systems in the Treatment of Wound Healing 12. Nanodrug Delivery Systems for Cosmetics 13. Novel Drug Delivery System for Rectal and Vaginal Targets 14. Nanoneutraceuticals and Their Applications
£146.30
