Organometallic chemistry Books

Book SynopsisA definitive reference source, written by practising experts in the field, providing detailed and up-to-date information on key aspects of metal catalysis.Trade ReviewThe essence is expertly and successfully distilled in such a way as to more than adequately cover the main points and each topic is presented in a manner that will stimulate further forays into the detailed scientific literature....be invaluable to postgraduate students, postdoctoral workers and their supervisors....appeal strongly to those working in industrial labs.It is a thoroughly good read and you may gather that I recommend it very highly. * Chemistry World, February 2007, p67 (Phil Barnes) *Is relatively compact and handy, but nevertheless covers broad areas of the subject.An interesting survey of metal catalysis as applied in industry. It is didactically well constructed and easy to read, and can be recommended for both students and teachers of organometallic chemistry as a valuable addition to the existing range of standard textbooks. * Angewandte Chemie International Ed., 2007, 46, 3791-3792 (Lukas J. GooBen) *"Metal-catalysis in Industrial Organic Processes" fills the gap in the market between text-books on homogeneous or heterogeneous catalysis and treatises on particular processes....excellent textbook....an accessible work that describes many of the more important processes in sufficient depth.I wholeheartedly recommend this excellent textbook to anybody with an interest in catalysis, either from an industrial or academic perspective. * Platinum Metals Review, 2007, 51 (4), 187-188 (Robin B Bedford) *It is a textbook that presents its material in concise form together with general analyses of tendencies and principles.I can recommend the book as an interesting introduction into the field of metal-catalyzed industrial processes for readers with a basic back-ground in organic chemistry. The book will also be helpful for the preparation of lectures on industrial chemistry and as a source of application examples for lectures on organometallic, synthetic, and catalytic chemistry. * Synthesis, 2007, No.13, pp 2064 (Lukas Hintermann) *Table of ContentsPreface; Glossary; Chapter 1: Introduction - Catalysis in the Chemical Industry Sunley; 1.1: Catalysis in the Chemical Industry; 1.2: Selection of a Chemical Process: What Does the Catalyst Do?; 1.3: Developing Metal-Catalysis - the Role of Fundamental Understanding; References; Chapter 2: Formation of C-O Bonds by Oxidation; 2.1: Review - The Basic Chemistry of Oxygen; 2.2: Cyclohexane Oxidation to Cyclohexanol and Cyclohexanone and to Adipic Acid: on the Way to Nylon-6,6; 2.3: p-Xylene Oxidation to Terephthalic Acid. Polyethylene Terephthalate: on the Way to Fibres for Shirts; 2.4: Ethylene Oxide by Ag-catalyzed Oxidation of Ethylene: for Antifreeze and Detergents; 2.5: Propylene Oxide: to Biocompatible Propylene Glycol; 2.6: Hydrogen Peroxide Route to Propylene Oxide; 2.7: Asymmetric Epoxidation, Dihydroxylation and Sulfide Oxidation: New Routes to Chiral Agrochemicals and Pharmaceuticals; 2.8: Acrolein and Acrylic Acid from Propylene: for Super-Absorbent Polymers, Paints, and Fibres; 2.9: Methacrolein and Methacrylic Acid from Isobutene; 2.10: Ammoxidation Reactions. Propylene to Acrylonitrile: for Engineering Plastics, Polymers; 2.11: Maleic Anhydride and Phthalic Anhydride: for THF, Spandex, Swim-suits and Ladies' Tights; 2.12: Silicalite Process to e-Caprolactam; 2.13: Oxidation of Phenol to Catechol and Hydroquinone; 2.14: Benzene Oxidation to Phenol: Making Phenolic Resins for Building; 2.15: Oxidation Processes in which the Metal Directly Functionalizes the Olefinic Substrate; 2.16: Enzymatic and Microbiological Oxidations. Microbial Hydroxylation of Progesterone; Annex 1: Alkane Feedstocks. Alternative Routes to Acetic Acid and Acrylonitrile; Annex 2: Adsorption Effects on the Catalytic Performances of TS-1. Zeolites as Solid Solvents; References; Chapter 3: Hydrogenation Reactions; 3.1: Introduction and Basic Chemistry: Activation of Hydrogen and Transfer to Substrate Isomerization Reactions; 3.2: Hydrotreating in Petroleum Chemistry; 3.3: Mono-unsaturated Fatty Esters by Partial Hydrogenation of Natural Oils; 3.4: Hydrogenation of Adiponitrile to Hexamethylenediamine; 3.5: Making L-DOPA by Enantioselective Hydrogenation of Acetamidoarylacrylic Acids; 3.6: Enantioselective Hydrogenation of N-Arylimines in the Synthesis of the Chiral Herbicide, (S )-Metolachlor; 3.7: Isomerization Reactions: Diethylgeranylamine and Diethylnerylamine for the Production of (_)-Menthol; 3.8: Enantioselective Hydrogen Transfer; 3.9: Ethylbenzene Dehydrogenation to Styrene; Discussion Points; References; Chapter 4: Syntheses Based on Carbon Monoxide; 4.1: Introduction; 4.2: Carbonylation Reactions of Alcohols and Esters; 4.3: Hydroxy/Alkoxy-Carbonylation of Alkenes and Dienes; 4.4: Polyketones; 4.5: Oxidative Carbonylation of Methanol to Dimethyl Carbonate and Dimethyl Oxalate; 4.6: Hydroformylation of Olefins; 4.7: CO Hydrogenation; Annex 1: Concerning the Mechanism of the Fischer-Tropsch Reaction; Annex 2: Some Hints for Discussion Points; References; Chapter 5: Carbon-Carbon Bond Formation; 5.1: Introduction; 5.2: Alkylation and Related Reactions; 5.3: Carbon-Carbon Bond Formation through Activation of Aryl- or Vinyl-Halide bonds: Fine Chemicals; 5.4: Chemistry of Allyl Compounds. Butadiene as Substrate; 5.5: Oligomerization of Olefins; 5.6: Carbene Chemistry and Asymmetric Synthesis: Chrysanthemic Esters; Annex 1: Devising New Synthetic Pathways; Annex 2: Hints to Improve or to Develop Alternative Processes for the Synthesis of Aromatics Catalyzed by Transition Metals; Annex 3: Perspectives in C-C Bond Forming Organic Syntheses; References; Chapter 6: Metathesis of Olefins; 6.1: Introduction - History and Basic Chemistry of Metathesis; 6.2: The Carbene-Metallacyclobutane Mechanism of Metathesis; 6.3: Industrial Applications of Metathesis; 6.4: Homogeneous Ruthenium Alkylidene Complexes; 6.5: Speciality Polymers; 6.6: Fine Chemicals and Pharmaceuticals; 6.7: Recent Progress; 6.8: Future Outlook; References; Chapter 7: Polymerization Reactions; 7.1: An Introductory Overview; 7.2: Industrial Aspects of Polyolefin Production; 7.3: Solid-State Polymerization Catalysts; 7.4: Soluble Olefin Polymerization Catalysts; 7.5: Supported Metallocene Catalysts; 7.6: Copolymerization of Linear and Cyclic Olefins; 7.7: Copolymerisation of Olefins with Polar Monomers and with CO; Annex 1: Polymer Stereochemistry Studied by 13C NMR Spectroscopy; Annex 2: Stereospecific Polymerization of Conjugated Diolefins: Butadiene and Isoprene; Annex 3: Some Hints to Help Start the Discussions; Acknowledgements; References; Appendix 1: Basic Organometallic Chemistry Related to Catalytic Cycles; References; Appendix 2: Some Basic Aspects of Surface Science Related to Heterogeneously Catalyzed Reactions; References; Subject Index

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Book SynopsisOrganometallic chemistry is an area which touches on, and plays an active role in, all of the traditional divisions of chemistry: inorganic, organic, physical and theoretical. This timely book provides overviews of recent original developments in these areas, including: the synthesis of main group, transition metal and lanthanide organometallics; applications to homogeneous catalysis; structural and theoretical studies; and enantioselective processes. As these topics are currently part of a stream of exciting research with potentially important industrial applications, this title presents informed accounts of state-of-the-art research which will be of great interest to readers. Written by some of the foremost groups in the field and handsomely illustrated throughout, each chapter also provides an extensive bibliography. By introducing areas that are likely to play a prominent role in organometallic chemistry in the near future, Perspectives in Organometallic Chemistry provides an authoTrade Review"... a series of thoughtfully written, specialised and topical accounts of different areas of organometallic research ... a good source of ideas ... " Journal of Organometallic Chemistry, Vol 689, Issue 10, 15 May 2004Table of ContentsGroup 15 element imido and phosphido cages; Coordination chemistry and synthetic applications; Neutral clusters EnRn of the monovalent elements gallium and indium. Recent results in synthesis and reactivity; New titanium imido chemistry with polydentate N-donor ligands; Organometallic complexes with 1,2-dichalcogenolate-o-carboranes; Synthesis and reactivities of multinuclear sulfur-bridged metal complexes ranging from dinuclear to hexanuclear cores; α,ω-Bis[(triphenylphosphine)gold(I)] hydrocarbons; Researches on non-classical organolanthanide chemistry; Hyper-structured alkynylruthenium complexes: Effect of dimensional evolution on NLO properties; Cycloaddition of alkynes mediated by [RuCp(L)]+ (L = CO, NCH, PH3) and RuCpCl complexes - Metallacyclopentatrienes as key intermediates- A DFT study; Selective C-C coupling reactions of Me2N-C=C-NMe2 at iron(0) centers; Routes to fluorinated organic derivatives by nickel mediated C-F activation of heteroaromatics; Novel η5 - η6 rearrangement of bis(fluorenyl)lanthanide complexes by the addition of AlR3; Results and perspectives of high oxidation state organomolybdenum chemistry in water; Modulation of electronic behaviour of metal-carbonyl clusters; Interionic and intermolecular solution structure of transition metal complexes by NMR; Synthetic and mechanistic pathways in platinum(II) chemistry; New perspectives for olefin complexes: Synthesis and characterisation of stable rhodium(0) and iridium(0) complexes; Substitution and addition reactions catalyzed by transition metal complexes; Late transition metal (Co, Rh, Ir)-siloxide complexes - Synthesis, structure and application to catalysis; Cheap chiral ligands for asymmetric transition metal catalyzed reactions; Chiral metal complexes in asymmetric catalysis; In search of asymmetric propargylic substitution reactions mediated by optically active indenyl-ruthenium(II) allenylidene complexes; Recent developments on hydride iridium triisopropylphosphine complexes:[IrH2(NCCH3)3(PiPr3)]BF4 as hydrogenation catalyst; Pd complex-catalyzed ring-opening polymerisation of 2-aryl-1-methylene-cyclopropanes; Subject Index

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Book SynopsisMetal-Organic Frameworks (MOFs) are crystalline compounds consisting of rigid organic molecules held together and organized by metal ions or clusters. Special interests in these materials arise from the fact that many are highly porous and can be used for storage of small molecules, for exampleH2 or CO2. Consequently, the materials are ideal candidates for a wide range of applications including gas storage, separation technologies and catalysis. Potential applications include the storage of hydrogen for fuel-cell cars, and the removal and storage of carbon dioxide in sustainable technical processes. MOFs offer the inorganic chemist and materials scientist a wide range of new synthetic possibilities and open the doors to new and exciting basic research. Metal-Organic Frameworks Materials provides a solid basis for the understanding of MOFs and insights into new inorganic materials structures and properties. The volume also reflects progress that haTable of ContentsContributors xi Series Preface xv Volume Preface xvii Part 1: Design and Synthesis 1 Porous Coordination Polymer Nanoparticles and Macrostructures 3Julien Reboul and Susumu Kitagawa Nanoscale Metal-Organic Frameworks 19Kyriakos C. Stylianou, Inhar Imaz and Daniel Maspoch Mesoporous Metal-Organic Frameworks 39Yao Chen and Shengqian Ma Porphyrinic Metal-Organic Frameworks 67Chao Zou, Min Zhao and Chuan-De Wu Fluorinated Metal-Organic Frameworks (FMOFs): Concept, Construction, and Properties 85Pradip Pachfule and Rahul Banerjee Synthesis and Structures of Aluminum-Based Metal-Organic Frameworks 99Norbert Stock Polyrotaxane Metal-Organic Frameworks 115Stephen J. Loeb and V. Nicholas Vukotic Photoreactive Metal-Organic Frameworks 135Anjana Chanthapally and Jagadese J. Vittal Edible Metal-Organic Frameworks 159Ross Stewart Forgan Mechanochemical Approaches to Metal-Organic Frameworks 173Tomislav Friščić Part 2: Post-Modification 193 Postsynthetic Modification of Metal-Organic Frameworks 195Andrew D. Burrows Part 3: Properties and Applications 219 Functional Magnetic Materials Based on Metal Formate Frameworks 221Ran Shang, Sa Chen, Zhe-Ming Wang and Song Gao Metal-Organic Frameworks from Single-Molecule Magnets 245Athanassios D. Katsenis, Euan K. Brechin and Giannis S. Papaefstathiou Open Metal Sites in Metal-Organic-Frameworks 259Yabing He and Banglin Chen Gas Storage in Metal-Organic Frameworks 283Muwei Zhang, Hao Li, Zachary Perry and Hong-Cai Zhou Metal-Organic Frameworks for Removal of Harmful Gases 303Jian Liu, B. Peter McGrail, Denis M. Strachan, Jun Liu, Jian Tian and Praveen K. Thallapally Adsorption of Hydrocarbons and Alcohols in Metal-Organic Framework Materials 321Debasis Banerjee, Benjamin J. Deibert, Hao Wang and Jing Li Metal Uptake in Metal-Organic Frameworks 343Michaele J. Hardie Photoreactive Properties Hosted in Metal-Organic Frameworks 363Victoria J. Richards, Thomas J. Reade, Michael W. George and Neil R. Champness Semiconducting Metal-Organic Frameworks 373Zhengtao Xu Patterning Techniques for Metal-Organic Frameworks 387Paolo Falcaro and Mark J. Styles Metal-Organic Frameworks in Mixed-Matrix Membranes 403Harold B. Tanh Jeazet and Christoph Janiak Electrochemical Properties of Metal-Organic Frameworks 419Frédéric Jaouen and Adina Morozan Applications of Metal-Organic Frameworks to Analytical Chemistry 443Na Chang, Cheng-Xiong Yang and Xiu-Ping Yan Recent Solid-State NMR Studies of Quadrupolar Nuclei in Metal-Organic Frameworks 457Yining Huang, Jun Xu, Farhana Gul-E-Noor and Peng He Part 4: Nets 471 Single-Crystal to Single-Crystal Transformations in Metal-Organic Frameworks 473Subhadip Neogi, Susan Sen and Parimal K. Bharadwaj Interpenetration and Entanglement in Coordination Polymers 523Stuart R. Batten Index 539

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Book SynopsisHeterometallic Coordination Copper (Ii) Compounds - Classification & Analysis of Crystallographic & Structural Data

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Book SynopsisOrganometallic chemistry is based on the reactions and use of a class of compounds (R-M) that contain a covalent bond between carbon and metal. They are prepared either by direct reaction of the metal with an organic compound or by replacement of a metal from another organometallic substance. Research in organometallic chemistry is also conducted in the areas of cluster synthesis, main-group derivatives in unusual oxidation states, organometallic polymers, unstable organometallic compounds and intermediates in matrices, structure determination of organometallic compounds in the solid state [X-ray diffraction] and gaseous states [electron diffraction], and mechanisms of reactions of transient silylenes and related species. In addition to the traditional metals and semimetals, elements such as selenium, lithium and magnesium are considered to form organometallic compounds, e.g. organomagnesium compounds MeMgI, iodo(methyl)magnesium and diethylmagnesium which are Grignard reagents an organo-lithium compound BuLi butyllithium; Organometallic compounds often find practical use as catalysts, the processing of petroleum products and the production of organic polymers.

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Book SynopsisIntermetallics is concerned with all aspects of ordered chemical compounds between two or more metals and notably with their applications. This book covers new and important research on the crystal chemistry and bonding theory of intermetallics; determination and analysis of phase diagrams; the nature of superlattices, antiphase domains and order-disorder transitions; the geometry and dynamics of dislocations and related defects in intermetallics; theory and experiments relating to flow stress, work-hardening, fatigue and creep; response of deformed intermetallics to annealing; magnetic and electrical properties of intermetallics; structure and properties of grain and interphase boundaries; the effect of deviations from stoichiometry on physical and mechanical properties; crystallisation of intermetallics from the melt or amorphous precursors.

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Book SynopsisThere is great interest in metallosupramolecular materials because of their use in magnetic, photonic and electronic materials. Functional Metallosupramolecular Materials focuses on the applications of these materials covering the chemistry underlying the synthesis of a variety of ligands to coordinate various metal ions and the generation of 2D and 3D materials based on these constructs. The book starts by looking at different metallosupramolecular systems including naturally occurring functional metallosupramolecular materials; DNA-based metallosupramolecular materials; metallopolymers; metallogels as well as functional materials based on MOFs. Subsequent chapters then systematically cover the different applications such as molecular computation, spin-crossover, light harvesting and as photocatalysts for the production of solar fuels. The book provides an overview of functional metallosupramolecular materials that will be of interest to graduate students, academics and industrial chemists interested in supramolecular chemistry, materials science and the materials applications.Table of ContentsNaturally Occurring Metallosupramolecular Materials as a Source of Inspiration for Biomimetic Materials; Constitutionally Dynamic Metallosupramolecular Materials; DNA/RNA-Based Metallosupramolecular Materials; Functional Materials Based on Metal-Containing Polymers; Recent Advances in Confined and Immobilized Metallopolymers; Metallosupramolecular Soft Materials: Metallogels; Functional Materials Based on MOFs; Surface Interface Studies of Functional Metallosupramolecular Materials; Metallosupramolecular Materials for Electronic Applications: Molecular Computation; Metallosupramolecular Materials for Magnetic Applications: Spin-Crossover; Metallosupramolecular Materials for Energy Applications: Light-Harvesting; Metallosupramolecular Assemblies for Energy/Environmental Applications: Conversion of Carbon Dioxide to Useful Products

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Book SynopsisMetal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.Table of ContentsMetal toxicity – essential elements/non-essential elements; Non-invasive assessment of brain iron overload; Chelators for imaging; Basic principles of metal chelation and chelation design; Synthetic strategies for therapeutic chelators; Therapeutic applications of chelation therapy; Treatment of systemic iron overload; Treatment of neurodegenerative diseases by chelators; Chelation of actinides, plutonium, uranium

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Book SynopsisWith the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in their field. This interdisciplinary field has the potential to provide answers to problems and challenges faced in catalysis, synthetic organic chemistry and the development of therapeutic agents and new materials. Providing an invaluable volume, Organometallic Chemistry Volume 41 contains analysed, evaluated and distilled information on the latest in organometallic chemistry research including developments and applications of Lewis acidic boron reagents, masked low-coordinate main group species in synthesis and the diiron centre.Table of ContentsRecent Developments and Applications of Lewis Acidic Boron Reagents; Masked Low-Coordinate Main Group Species in Synthesis; The Diiron Centre: Fe2(CO)9 and friends; Taddol and Binol-derived Chiral Phosphonites in Asymmetric Catalysis; Gold-catalysed C-F Bond Activation; Silylamides: Towards a Half-century of Stabilising Remarkable f-Element Chemistry

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Book SynopsisThe metal–ligand coordination of metallomacrocycles allows for the production of both discrete and infinite metallosupramolecular structures with high-degrees of complexity. In recent years, coordination-driven self-assembly has emerged as a powerful noncovalent synthetic strategy to build discrete supramolecular architectures with diverse coordination moieties such as a well-defined shape, size, and geometry. The dynamic features of the metal–ligand bonds result in structures with intriguing properties allowing for a diverse range of applications in host–guest chemistry, sensing, drug delivery and catalysis. This book provides a comprehensive summary of current research in metallomacrocycles. Starting with an introduction to metallomacrocycles constructed via coordination-driven self-assembly, the book then goes on to explore design principles and self-organization. Subsequent chapters then discuss examples of complex and functional metallosupramolecular systems based on metallomacrocycles such as chiral systems and mechanically interlocked architectures. Finally, the book discusses the applications of metallomacrocycles. An essential resource for students and researchers looking to design and construct new metallosupramolecular systems and extend their applications in biological and materials science.Table of ContentsEvolution of Metallomacrocycles From Macrocycles; Design Principles of Selfassembled Metallomacrocycles; Self-organization in Coordination-driven Selfassembled Metallomacrocyles; Self-assembled Chiral Metallomacrocycles; Half-sandwich Iridium- and Rhodium-based Organometallic Macrocycles; Supramolecular Transformations of Metallomacrocycles; Coordination-driven Selfassembly of Functionalized Selfassembled Metallomacrocycles; Higher-order Supramolecular Systems Derived From Selfassembled Metallomacrocycles; Applications of Self-assembled Metallomacrocycles I: Biological Applications; Applications of Self-assembled Metallomacrocycles II: Catalysis and Sensing

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Book SynopsisThere is a growing interest in the development of sustainable processes for the synthesis of pharmaceuticals and this book bridges the divide between industrial examples and the fundamental chemistry. It explains the basic principles of using transition metal catalysis with several green approaches for the synthesis of pharmaceuticals. The topic is an important one for green chemistry and the chapters in this book on hydroformylation, green oxidation and olefin metathesis will also be of interest to both medicinal and organic chemists. Written by leading experts in the field, it provides a valuable and easy tool for scientists and industrialists who require information regarding this topic.Table of ContentsIntroduction; Transition Metals in Greener Pharmaceutical Chemistry; Sustainable Synthesis of Pharmaceuticals Using Alternative Techniques: Microwave, Sonochemistry and Mechanochemistry; Carbonylation Reactions in the Synthesis of Pharmaceutically Active Compounds; Applications of Catalytic Hydroformylation in the Synthesis of Biologically Relevant Synthons and Drugs; Transfer Hydrogenation with Non-toxic Metals for Drug Synthesis; Green Metal-catalysed Synthesis of Pharmaceutically Useful Asymmetric Epoxides and Sulfoxides; C–C Bond Formation in the Sustainable Synthesis of Pharmaceuticals; Metal-catalysed Metathesis Reactions for Greener Synthon/Drug Synthesis; Tetravalent Boron-based Therapeutics

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Book SynopsisCatalysis remains a key technology in a huge number of industrial processes in the 21st century. The catalytic properties of precious metals such as platinum and palladium are well understood. However, these metals are expensive and their supply is limited. Earth-abundant elements such as iron and nickel are, as the name suggests, in plentiful supply and much cheaper to use, but research on their use in catalysis has, historically, lagged behind. As researchers and companies increasingly look for ways to reduce costs and improve the sustainability of their processes there has been a renewed interest in these earth-abundant elements. This book presents a detailed overview of current research on the catalytic uses of the most Earth-abundant elements. Highlighting the top ten most Earth-abundant elements and their various roles in modern synthetic chemistry: s-block metals (Na, K, Mg, Ca), first-row transition metals (Ti, Mn, Fe), and p-block elements (Al, Si, P). The significant stoichiometric use of these elements, and their use as acid, base, dual, and/or redox catalysts will be discussed. It will be of use to industrial and academic researchers as well as graduate students with an interest in catalysis and sustainability.Table of ContentsNa (including catalysis); K (including catalysis); Mg (stoichiometric use); Mg/Ca (catalysis) ; Mg/Ca (asymmetric catalysis); Ti (including catalysis); Mn (catalysis I); Mn (catalysis II); Fe (mechanistic studies); Fe (catalysis); Al (including catalysis); Si (stoichiometric use); Si (catalytic intermediates); P (acid catalysis); P (base catalysis)

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Book SynopsisMetal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes used for both therapy and drug delivery, promise a bright future beyond the benefits of pure cytotoxic activity. With contributions from global leaders in the field, this book will serve as a useful reference to established researchers as well as a practical guide to those new to metallodrugs, and postgraduate students of medicinal chemistry and metallobiology.Table of ContentsEnhancing the Therapeutic Potential of Platinum-Based Anti-Cancer Agents by Incorporating Clinically Approved Drugs as Ligands; Ruthenium, Osmium and Iridium in the Fight Against Cancer; Iron Compounds as Anticancer Agents; Recent Advances in Anticancer Copper Compounds; Anticancer Gold Compounds; Heterometallic Complexes as Anticancer Agents; Vanadium Compounds as Enzyme Inhibitors with a Focus on Anticancer Effects; Arsenic-based Anticancer Agents; Supramolecular Metal-based Structures for Applications in Cancer Therapy; Enabling Methods to Elucidate the Effects of Metal-based Anticancer Agents; Metal-Based Radiotherapeutics; Challenges and Chances in the Pre-clinical to Clinical Translation of Anticancer Metallodrugs

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Book SynopsisProviding an invaluable resource, this volume contains analysed, evaluated and distilled information on the latest in organometallic and coordination chemistry research and emerging fields. With the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in their field. The reviews range in scope and include recent advances in chromium coordination chemistry, borohydride and borane ligand architectures supported by heterocyclic units and discussion on behaviours of novel ruthenium(II) complexes. This volume is a key reference for researchers in academic and industrial settings.Table of ContentsRecent Advances in Chromium Coordination Chemistry: Luminescent Materials and Photocatalysis; Organometallic Compounds of Ruthenium and their Application in Chemotherapy; Multinuclear Catalysts for the Ring-Opening Polymerisation of Cyclic Esters; Design of Gadolinium Complexes as Magnetic Resonance Imaging Contrast Agents; Advances in the Chemistry of Metal-Metal Quadruple Bonds 2015-2020; Transition Metal Complexes of Borane and Borohydride Ligand Architectures Containing a Single Tethering Supporting Unit; Applied Organometallics: Cp*Co(III)-Catalysed C-H Functionalisation as a Maturing Tool for the Synthesis of Heterocyclic Compounds

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Book Synopsis

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Book Synopsis

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Book SynopsisProviding an invaluable resource, this volume contains analysed, evaluated and distilled information on the latest in organometallic and coordination chemistry research and emerging fields. With continued increases in the variety of information available, researchers can find it difficult to keep up to date with the literature in their field. The reviews in this volume range in scope and include recent developments in homogeneous catalysis for the functionalization of carbon dioxide, early transition metal complexes and their uses in medicinal chemistry, homogeneous gold catalysis under microwave irradiation: a greener approach and properties of metal complexes of mesoionic carbenes. This volume is a key reference for researchers in academic and industrial settings.Table of ContentsPreface;Redox and photochemical/photophysical properties of compounds containing mesoionic carbene ligands;Recent developments in homogeneous catalysis for the functionalisation of CO2 ;Homogeneous gold catalysis under microwave irradiation: A greener approach;Medicinal applications of early transition metal β-diketonato complexes

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Book SynopsisBased on a translated Japanese title published in 2012, this book provides fundamental aspects of experimental and computational methods, the properties and structure of solvents, ion solvation and equilibria and reactions of metal complexes in solution. It includes state-of-the-art details on metal complexes in newly developing sustainable liquids and applications in real life. Appealing to researchers working in coordination chemistry, including students and industrialists, the text uses exercises, tables and figures to help the reader with their understanding of the topic.Table of ContentsThermodynamic Measurements (Potentiometry, UV-Vis Spectrometry and Calorimetry);X-ray and Neutron Scattering;X-ray Absorption Spectroscopy;Nuclear Magnetic Resonance;Vibrational Spectroscopy;Computational Approach;Solvent Properties;Solvent Structures;Hydration and Solvation of Metal Ions;Ion Solvation in Non-aqueous and Mixed Solvents;Reactions of Metal Complexes in Solution;Electron Transfer Reactions in Solution;Metal Complexes in Supercritical Fluids;Reactions and Equilibria of Metal Complexes Under High Pressure;Metal Complexes in Ionic Liquids;Metal Complexes in Micellar and Liquid Crystalline Solutions;Inorganic Biochemistry;Solvent Extraction;Complex Formation in Hyperalkaline Solutions;Resources Separation from Salt Lake Brine

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Book SynopsisThere has been increasing research into designing transition metal-containing dendrimers as innovative materials, especially in the field of biomedicine and pharmaceutical science. They have applications in biosensors and drug-delivery systems, and are now one of the leading classes in the design of therapeutics for drug-resistant diseases. This book introduces readers to a number of classes of metal-containing dendrimers, before moving onto their design and synthesis. Their applications in biomedicine are then discussed, before highlighting future research targets in this growing field. It emphasizes the synthetic strategies to design transition metal-containing dendrimers, and discusses the type of laboratory work used to examine these types of dendrimers in the fields of medicine and pharmacology, including their antimicrobial, anticancer, anti-inflammatory and antiviral activities. Transition Metal-Containing Dendrimers in Biomedicine brings chemistry, biology, pharmaceutical science and medical fields together to design these future materials which will have global benefits.Table of ContentsIntroduction;Antimicrobial Activity of Metal-containing Dendrimers;Anticancer Activity of Metal-containing Dendrimers;Other Therapeutic Applications;Biosensors and Bioimaging

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Book SynopsisSamarium diiodide is one of the most important reducing agents available to synthetic organic chemists. The lanthanide(II) reagent acts by single-electron transfer to organic substrates leading to the formation of both radical and/or anionic intermediates. The power of the reagent arises from its versatility - samarium diiodide can be used in processes ranging from functional group conversions to elaborate carbon-carbon bond-forming cyclization sequences that result in a dramatic increase in molecular complexity. In addition, reactions involving samarium diiodide often show high stereoselectivity as samarium ions can coordinate to Lewis basic sites on substrates and can direct the stereochemical course of reactions. The ability to fine-tune the reactivity of the reagent by the use of additives and co-solvents is an additional, attractive feature. Although samarium diiodide is used extensively by organic chemists, there is still a widely held view that the reagent can be difficult to prepare and use. In addition, samarium diiodide can mediate such a wide variety of organic chemistry that potential new users are often overawed by the extensive primary literature on the reagent. The objective of this book is to provide a concise, practical guide to the reagent. Rather than being a comprehensive review of the chemistry of samarium diiodide, this user-friendly book adopts an "an all you need to know" approach to the topic. The international authors are well-known for their work with the reagent and their expertise covers current developments in new reactivity and selectivity, applications in target synthesis, co-solvent and additive effects, coordination chemistry and mechanism. The book includes the best methods for preparing and handling the reagent, how solvents, co-solvents and additives alter reactivity, the basic mechanisms of reactions, common transformations using the reagent, and emerging areas in samarium diiodide chemistry. The authors have distilled the extensive primary literature to allow the reader to quickly grasp an understanding of the reagent and its utility. The illustrative practical procedures help the reader to prepare and use the reagent in the laboratory while references from the recent literature allow readers to pursue their interest in the popular reagent. The book also contains many illustrations and chemical schemes.Table of ContentsChapter 1: Introduction; Chapter 2: The reagent and the effect of additives; Chapter 3: Mechanisms of SmI2-mediated reactions - the basics; Chapter 4: Functional group transformations using SmI2; Chapter 5: Carbon-carbon bond-forming reactions using SmI2; Chapter 6: Sequential carbon-carbon bond formation using SmI2; Chapter 7: Emerging areas;

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Book SynopsisOrganometallic Chemistry is an interdisciplinary science which continues to grow at a rapid pace. Although there is continued interest in synthetic and structural studies, the last decade has seen a growing interest in the potential of organometallic chemistry to provide answers to problems in synthetic organic chemistry, the development of new materials and catalysis. This Specialist Periodical Report aims to reflect these current interests, and since Volume 34 provides both comprehensive and critical reviews of the recent literature. Topics examined in this volume include heterocyclic carbene compounds, coinage metals and paddlewheel compounds.Table of ContentsPreface; Non-transition metal N-heterocyclic carbene complexes; Bis(phosphorus-stabilised)methanide and methandiide derivatives of group 1û5 and f-element metals; The stabilisation of organometallic complexes using m-terphenyl ligands The Pauson-Khand reaction; Scandium, Yttrium and the Lanthanides; Alkali/coinage metals û organolithium, organocuprate chemistry; Group 2 (Be-Ba) and group 12 (Zn-Hg); Organo-transition metal cluster complexes

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Book SynopsisA series of critical reviews and perspectives focussing on specific aspects of organometallic chemistry interfacing with other fields of study are provided. For this volume, the critical reviews cover topics such as the activation of "inert" carbon-hydrogen bonds, ligand design and organometallic radical species. For example, Charlie O'Hara discusses how mixed-metal compounds may perform the highly selective activation of C-H bonds and, in particular, how synergic relationships between various metals are crucial to this approach. The chemistry of a remarkable series of air-stable chiral primary phosphine ligands is discussed in some depth by Rachel Hiney, Arne Ficks, Helge M³ller-Bunz, Declan Gilheany and Lee Higham. This article focuses on the preparation of these ligands and also how they may be applied in various catalytic applications. Bas De Bruin reports on how ligand radical reactivity can be employed in synthetic organometallic chemistry and catalysis to achieve selectivity in radical-type transformations. As well as highlighting ligand-centered radical transformations in open-shell transition metals, an overview of the catalytic mechanism of Co(II)-catalysed olefin cyclopropanation is given, showing that enzyme-like cooperative metal-ligand-radical reactivity is no longer limited to real enzymes. Valuable and informative comprehensive reviews in the field of organometallic chemistry are also covered in this volume. For example, organolithium and organocuprate chemistry are reviewed by Joanna Haywood and Andrew Wheatley; aspects in Group 2 (Be-Ba) and Group 12 (Zn-Hg) compounds by Robert Less, Rebecca Melen and Dominic Wright; metal clusters by Mark Humphrey and Marie Cifuentes; and recent developments in the chemistry of the elements of Group 14 - focusing on low-coordination number compounds by Richard Layfield. This volume therefore covers many synthetic and applied aspects of modern organometallic chemistry which ought to be of interest to inorganic, organic and applied catalysis fields.Table of ContentsPreface; Synergistic effects in the activation of small molecules by s-block elements; Air-stable chiral primary phosphines: part (i) synthesis, stability and applications; Open-shell organometallics: reactivity at the ligand; Alkali/coinage metals - organolithium, organocuprate chemistry; Group 2 (Be-Ba) and Group 12 (Zn-Hg); Organo-transition metal cluster complexes; Highlights in low-coordinate group 14 organometallic chemistry;

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Book SynopsisA series of critical reviews and perspectives focussing on specific aspects of organometallic chemistry interfacing with other fields of study are provided. For this volume, the critical reviews cover topics such as the activation of "inert" carbon-hydrogen bonds, ligand design and organometallic radical species. For example, Charlie O'Hara discusses how mixed-metal compounds may perform the highly selective activation of C-H bonds and, in particular, how synergic relationships between various metals are crucial to this approach. The chemistry of a remarkable series of air-stable chiral primary phosphine ligands is discussed in some depth by Rachel Hiney, Arne Ficks, Helge M³ller-Bunz, Declan Gilheany and Lee Higham. This article focuses on the preparation of these ligands and also how they may be applied in various catalytic applications. Bas De Bruin reports on how ligand radical reactivity can be employed in synthetic organometallic chemistry and catalysis to achieve selectivity in radical-type transformations. As well as highlighting ligand-centered radical transformations in open-shell transition metals, an overview of the catalytic mechanism of Co(II)-catalysed olefin cyclopropanation is given, showing that enzyme-like cooperative metal-ligand-radical reactivity is no longer limited to real enzymes. Valuable and informative comprehensive reviews in the field of organometallic chemistry are also covered in this volume. For example, organolithium and organocuprate chemistry are reviewed by Joanna Haywood and Andrew Wheatley; aspects in Group 2 (Be-Ba) and Group 12 (Zn-Hg) compounds by Robert Less, Rebecca Melen and Dominic Wright; metal clusters by Mark Humphrey and Marie Cifuentes; and recent developments in the chemistry of the elements of Group 14 - focusing on low-coordination number compounds by Richard Layfield. This volume therefore covers many synthetic and applied aspects of modern organometallic chemistry which ought to be of interest to inorganic, organic and applied catalysis fields.Table of ContentsPreface; Organometallic Aspects of C-H Activation / Functionalisation; New Developments in the Biomedical Chemistry of Transition Metal Complexes; From Small Molecules to Nanotheranostics Design; TBC; Group 1; Organo-transition Metal Cluster Complexes; The Application of NACNAC Complexes; Synthesis and Application of Novel Primary Phosphine Ligands: Part 2

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Book SynopsisA series of critical reviews and perspectives focussing on specific aspects of organometallic chemistry interfacing with other fields of study are provided. For this volume, the critical reviews cover topics such as the activation of "inert" carbon-hydrogen bonds, ligand design and organometallic radical species. For example, Charlie O'Hara discusses how mixed-metal compounds may perform the highly selective activation of C-H bonds and, in particular, how synergic relationships between various metals are crucial to this approach. The chemistry of a remarkable series of air-stable chiral primary phosphine ligands is discussed in some depth by Rachel Hiney, Arne Ficks, Helge M³ller-Bunz, Declan Gilheany and Lee Higham. This article focuses on the preparation of these ligands and also how they may be applied in various catalytic applications. Bas De Bruin reports on how ligand radical reactivity can be employed in synthetic organometallic chemistry and catalysis to achieve selectivity in radical-type transformations. As well as highlighting ligand-centered radical transformations in open-shell transition metals, an overview of the catalytic mechanism of Co(II)-catalysed olefin cyclopropanation is given, showing that enzyme-like cooperative metal-ligand-radical reactivity is no longer limited to real enzymes. Valuable and informative comprehensive reviews in the field of organometallic chemistry are also covered in this volume. For example, organolithium and organocuprate chemistry are reviewed by Joanna Haywood and Andrew Wheatley; aspects in Group 2 (Be-Ba) and Group 12 (Zn-Hg) compounds by Robert Less, Rebecca Melen and Dominic Wright; metal clusters by Mark Humphrey and Marie Cifuentes; and recent developments in the chemistry of the elements of Group 14 - focusing on low-coordination number compounds by Richard Layfield. This volume therefore covers many synthetic and applied aspects of modern organometallic chemistry which ought to be of interest to inorganic, organic and applied catalysis fields.Table of ContentsSilver-N-Heterocyclic Carbenes as Promising Anti-Cancer Agents; The Chemistry of NacNac Complexes; Developments in Multiply-Bonded Group 14 Organometallic Chemistry; Alkali/Coinage Metals - Organolithium, Organocuprate Chemistry; Cluster Chemistry of the Transition Metals

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Book SynopsisHeme peroxidases are widely distributed in biological systems and are involved in a wide range of processes essential for life. This book provides a comprehensive single source of information on the various aspects of heme peroxidase structure, function and mechanism of action. Chapters written and edited by worldwide experts span a range of heme peroxidases from plants, yeast, bacteria and mammals. Discussed functions of peroxidases range from cell wall synthesis, synthesis of prostaglandins, role in drug suppression of tuberculosis, and antibacterial activity. Included is a discussion of peroxidases that also act as catalases and oxygenases. Heme Peroxidases serves as an essential text for those working in industry and academia in biochemistry and metallobiology.Table of ContentsSelf-processing peroxidases; Cytochrome c peroxidase and cytochrome c complexes; Understanding the reactivity and interactions of peroxidases with substrates; Structural and functional properties of heme containing peroxidases; Heme Peroxidase Kinetics; Multiheme peroxidases; Catalase-peroxidase (KatG) structure and function; Mechanistic aspects of catalase-peroxidase; Models complexes of heme peroxidases; Mult-functional hemoglobin dehaloperoxidases; The Peroxidase and Cyclooxygenase Activity of Prostaglandin H Synthase; Myeloperoxidase: Structure and Function of the Green Peroxidase of Neutrophils; Peroxidases as Potential Industrial Biocatalysts; Structural and Reactivity of the Dyedye-decolorizing peroxidases (DyP) Family

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Book SynopsisQuantum dots are nano-sized particles of semiconducting material, typically chalcogenides or phosphides of metals found across groups II to VI of the periodic table. Their small size causes them to exhibit unique optical and electrical properties which are now finding applications in electronics, optics and in the biological sciences. Synthesis of these materials began in the late 1980’s and this book gives a thorough background to the topic, referencing these early discoveries. Any rapidly-expanding field will contain vast amounts of publications, and this book presents a complete overview of the field, bringing together the most relevant and seminal aspects literature in an informed and succinct manner. The author has been an active participant in the field since its infancy in the mid 1990’s, and presents a unique handbook to the synthesis and application of this unique class of materials. Drawing on both his own experience and referencing the primary literature, Mark Green has prepared. Postgraduates and experienced researchers will benefit from the comprehensive nature of the book, as will manufacturers of quantum dots and those wishing to apply them.Trade ReviewThe fi eld of nanotechnology is growing. The tunability of nano-objects such as semiconductor quantum dots (SQDs) has spurred interest in chemical synthesis. In this regard, this book’s arrival is timely. It groups the various synthesis techniques for popular SQDs, comprised of 295 pages distributed among seven chapters and a comprehensive subject index. Preparation methods for II–VI, II–V, and IV–VI SQDs are described in the fi rst three chapters. The fi rst chapter introduces and develops various organometallic routes to the synthesis of Zn and Hg chalcogenides and anisotropic growth of Cd-based chalcogenides such as tetrapods and their alloys. Properties of Group III phosphides, nitrides, arsenides, and antimonides, which have different optical properties compared to II–VI semiconductors, are discussed in chapter 2. This chapter also reviews the tuning of SQD properties via dehalosilylation reactions and non-coordinating solvent routes. It is shown that the quantum yield can be increased by varying precursors and their quantities. Anisotropic nanoparticles with rod-like morphologies have also been examined in terms of challenges faced during their synthesis. Lead-based chalcogenide properties and synthesis routes are outlined in chapter 3. Chapter 4 deals with the synthesis of other chalcogenides and pnictide-based materials. Ternary copper-based chalcogenide core–shell and II3-V2 quantum dots include CuInSe2 and Cd3P2, respectively, among many others. Chapter 5 discusses surface passivation by means of synthesizing an inorganic capping layer or a core– shell structure. This thorough chapter is of fundamental and practical interest. It describes Type I and Type II core shells and multiple shell structures targeting a higher quantum yield. There are also sections relating to III–V and IV–VI core–shell structures. Chapter 6 unfolds ligand chemistry and the purpose of ligands in shaping the nanoparticles. Chapter 7 describes the role that the capping agent or the surfactant plays in terms of its linkable functional moieties. Various surfactants have been brought to the reader’s attention, namely amines and thiols, among others, along with surfactant exchanges based upon them. The book also covers “green chemistry” synthesis aspects of SQDs and the use of biological molecules as capping agents, viz., DNA. Consideration is given to the toxicity of the solvents and the search for phosphine-free systems. Overall, the book is eye-catching with ample illustrations and interesting, as the chapter sequence is well conceived. Moreover, every chapter brings something new to the reader accompanied by historical facts pertaining to various SQD syntheses. As the book is clearly subtitled “synthesis” and is dedicated to organometallic and inorganic synthesis, it would be most suited to synthetic chemists. However, the physical properties of various SQDs also are well illustrated, and this volume is therefore of some interest to materials scientists and nanotechnologists. -- Protima Rauwel * MRS Bulletin *Table of ContentsII-VI Materials; III-V Materials; IV-VI Materials; Other Chalcogens and Phosphides; Core/Shell Particles; Ligand Chemistry; Single Source Precursors

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Book SynopsisEarly Main Group Metal Catalysis gives a comprehensive overview of catalytic reactions in the presence of group 1 and group 2 metals. Chapters are ordered to reaction type, contain educational elements and deal with concepts illustrated by examples that cover the main developments. After a short introduction on polar organometallic chemistry and synthesis of early main group metal complexes, a variety of catalytic reactions are described, e.g. polymerization of alkenes, hydroamination and phosphination reactions, hydrosilylation, hydroboration and hydrogenation catalysis, as well as enantioselective and Lewis-acid catalysis. The book addresses organic chemists and researchers in industry interested in the state-of-the-art and new possibilities of early main group metal catalysis as well as newcomers to the field. Written by a team of leaders in the field, it is a very welcome addition to the area of main group metal chemistry, and to the field of catalysis.Table of ContentsPreface xiii 1 Introduction to Early Main Group Organometallic Chemistry and Catalysis 1Sjoerd Harder 1.1 Introduction 1 1.2 s-Block Organometallics 1 1.2.1 Short History 1 1.2.2 Synthesis of Group 1 Organometallics 2 1.2.3 Synthesis of Group 2 Organometallics 4 1.2.4 Bonding and Structures of s-Block Organometallics 8 1.2.5 Dynamics of s-Block Organometallics in Solution 13 1.2.6 Low-Valent s-Block Chemistry 16 1.3 s-Block Organometallics in Catalysis 17 1.3.1 Working Principles in Lewis Acid Catalysis 17 1.3.2 Working Principles in s-Block Organometallic Catalysis 19 1.3.3 Substrate Activation by s-Block Metals 21 1.3.4 Future of Early Main Group Metal Catalysis 23 List of Abbreviations 24 References 24 2 Polymerization of Alkenes and Polar Monomers by Early Main Group Metal Complexes 31Sjoerd Harder 2.1 Introduction 31 2.2 Alkene Polymerization 32 2.2.1 Styrene Polymerization 33 2.2.2 Polymerization of Modified Styrene 40 2.2.3 Polymerization of Butadiene or Isoprene 43 2.3 Polymerization of Polar Monomers 45 2.3.1 Polymerization of Lactides 45 2.3.2 Copolymerization of Epoxides and CO2 50 2.4 Conclusions 53 List of Abbreviations 54 References 54 3 Intramolecular Hydroamination of Alkenes 59Sebastian Bestgen and Peter W. Roesky 3.1 Introduction 59 3.2 Hydroamination 60 3.2.1 Scope 62 3.3 s-Block Metal Catalysis 64 3.3.1 General Remarks 64 3.3.2 Mechanistic Aspects 65 3.3.3 Group 1-Based Catalysis 68 3.3.3.1 Concerted Reaction 68 3.3.3.2 Radical-Mediated Intramolecular Hydroamination 71 3.3.3.3 Reactions of N-Arylhydrazones and Ketoximes 72 3.3.4 Group 2 Metal-Mediated Catalysis 74 3.3.5 Group 2-Mediated Asymmetric Cyclohydroamination 83 3.3.6 Lewis Acidic Metal Cation Catalysis 84 3.3.7 Miscellaneous 85 3.4 Outlook 86 Acknowledgments 87 List of Abbreviations 87 References 88 4 Molecular s-Block Catalysts for Alkene Hydrophosphination and Related Reactions 93Yann Sarazin and Jean-François Carpentier 4.1 Introduction 93 4.2 General Considerations 95 4.3 Hydrophosphination of Alkenes 96 4.3.1 Precatalysts with Nitrogen-Based Ligands 97 4.3.2 Precatalysts with Oxygen-Based Ligands 110 4.4 Hydrophosphination of Carbodiimides 112 4.5 Miscellaneous Reactions 114 4.5.1 Hydrophosphinylation of Alkenes and Enones 114 4.5.2 Hydrophosphonylation of Aldehydes and Ketones 116 4.6 Summary and Conclusions 117 List of Abbreviations 118 References 118 5 H—Nand H—P Bond Addition to Alkynes and Heterocumulenes 123Sven Krieck and Matthias Westerhausen 5.1 Introduction 123 5.2 Hydroamination 124 5.2.1 Hydroamination with Secondary Amines 125 5.2.2 Hydroamination with Primary Amines 128 5.2.3 Proposed Mechanisms for the Hydroamination of Butadiynes 130 5.3 Hydrophosphanylation (Hydrophosphination) 134 5.4 Hydrophosphorylation and Hydrophosphonylation 138 5.5 Summary and Conclusions 143 5.6 Acknowledgments 146 5.7 Abbreviations 146 References 146 6 Early Main Group Metal-Catalyzed Hydrosilylation of Unsaturated Bonds 151Sjoerd Harder 6.1 Introduction 151 6.2 Historical Development 151 6.3 Nonprecious Metal Hydrosilylation Catalysts 153 6.4 C=C Bond Hydrosilylation with s-Block Metal Catalysts 155 6.5 C=O Bond Hydrosilylation with s-Block Metal Catalysts 161 6.6 C=N Bond Hydrosilylation with s-Block Metal Catalysts 167 6.7 Conclusions 170 References 171 7 Early Main Group Metal Catalyzed Hydrogenation 175Heiko Bauer and Sjoerd Harder 7.1 Introduction 175 7.2 Hydrogenation of C=C Double Bonds 178 7.3 Hydrogenation of C=N Double Bonds 187 7.4 Hydrogenation of C=O Double Bonds 191 7.5 Summary and Perspectives 194 References 197 8 Alkali and Alkaline Earth Element-Catalyzed Hydroboration Reactions 201Aaron D. Sadow 8.1 Introduction and Overview 201 8.2 Thermodynamic Considerations 203 8.2.1 Hydroboration, Hydrosilylation, and Hydrogenation 203 8.2.2 Thermochemistry of Metal–Oxygen Bonds and Element–Hydrogen Bonds 205 8.3 Group 1-Catalyzed Hydroboration Reactions 207 8.3.1 Overview 207 8.3.2 Base-Catalyzed Hydroborations 207 8.3.3 Alkali Metal Hydridoborate and Aluminate-Catalyzed Hydroboration 210 8.4 Group 2-Catalyzed Hydroboration Reactions 214 8.4.1 Overview 214 8.4.2 β-Diketiminate Magnesium-Catalyzed Hydroborations 215 8.4.3 Tris(4,4-dimethyl-2-oxazolinyl)phenylborato Magnesium-Catalyzed Hydroboration of Ester and Amides 217 8.4.4 Magnesium Triphenylborate-Catalyzed Hydroboration 221 8.4.5 Supported Catalysts for Hydroboration 221 8.5 Summary and Conclusions 222 References 222 9 Dehydrocoupling and Other Cross-couplings 225Merle Arrowsmith 9.1 Introduction 225 9.2 Early Main Group-Catalyzed Cross-DHC of Amines and Boranes 228 9.2.1 Early Stoichiometric Studies with s-Block Elements 228 9.2.2 s-Block-Catalyzed Cross-dehydrogenative Synthesis of Diaminoboranes 229 9.2.3 s-Block-Catalyzed DHC of DMAB 231 9.2.4 Calcium-Catalyzed Dehydrocoupling of tert-Butylamine Borane 235 9.2.5 s-Block-Catalyzed DHC of Amines and Monohydroboranes 235 9.3 s-Block-Catalyzed Cross-DHC of Amines and Silanes 238 9.3.1 Influence of Precatalysts and Substrates on Reactivity and Selectivity 238 9.3.2 Mechanistic and Computational Analysis 240 9.3.3 Application to the Synthesis of Oligo- and Polysilazanes 242 9.4 Other s-Block-Catalyzed Cross-DHC Reactions 243 9.4.1 Alkali Metal-Catalyzed DHC of Si—H and O—H Bonds 243 9.4.2 s-Block-Catalyzed DHC of Si—H and C—H Bonds 243 9.5 Early Main Group-Mediated Nondehydrogenative Cross-couplings 244 9.6 Conclusion and Outlook 245 References 246 10 Enantioselective Catalysis with s-Block Organometallics 251Philipp Stegner and Sjoerd Harder 10.1 Introduction 251 10.2 Lithium-Based Catalysts 252 10.2.1 Lithium Catalysts Based on Neutral Chiral Ligands 252 10.2.2 Lithium Catalysts Based on Monoanionic Chiral Ligands 255 10.2.3 Lithium Catalysts Based on Dianionic Chiral Ligands 257 10.3 Potassium-Based Catalysts 259 10.3.1 Potassium Catalysts Based on Monoanionic Chiral Ligands 260 10.4 Magnesium-Based Catalysts 262 10.4.1 Magnesium Catalysts Based on Monoanionic Chiral Ligands 263 10.4.2 Magnesium Catalysts Based on Dianionic Chiral Ligands 266 10.5 Calcium-Based Catalysts 269 10.5.1 Calcium Catalysts Based on Monoanionic Chiral Ligands 269 10.5.2 Calcium Catalysts Based on Dianionic Chiral Ligands 273 10.6 Conclusion and Outlook 275 List of Abbreviations 275 References 276 11 Early Main Group Metal Lewis Acid Catalysis 279Marian Rauser, Sebastian Schröder, and Meike Niggemann 11.1 Introduction 279 11.1.1 Lewis Acidity of s-Block Metal Cations 280 11.1.2 Interactions with More than One Lewis Base 281 11.1.3 Counter Anions 282 11.1.4 Solvation 283 11.1.5 Solubility and Aggregation 283 11.1.6 Water Tolerance 284 11.1.7 Relative Lewis Acid Activity of Alkaline and Alkaline Earth Metals 285 11.1.8 Hidden Brønsted Acid 287 11.2 Polarized Carbon–Heteroatom Double Bonds 287 11.2.1 Carboxylates: Anhydrides and Carbonates 288 11.2.2 Aldehydes, Ketones, and Formates 289 11.2.3 α,β-Unsaturated Carbonyl Compounds 291 11.2.4 Imines and Enamines 292 11.2.5 Mannich Reactions 294 11.2.6 Oxidation and Reduction 294 11.2.7 Donor–Acceptor Cyclopropanes 294 11.2.8 Diels–Alder Reaction and Cycloaddition 295 11.3 Activation of Polarized Single Bonds 296 11.3.1 Opening of Three-Membered Heterocycles 296 11.3.2 Leaving Groups 297 11.3.3 Ca2+-Catalyzed Dehydroxylation as a Special Case 299 11.4 Activation of Unpolarized Double Bonds 305 11.5 Summary and Conclusions 307 References 307 12 Enantioselective Group 2Metal Lewis Acid Catalysis 311Yasuhiro Yamashita, Tetsu Tsubogo, and Shū Kobayashi 12.1 Introduction 311 12.2 Catalytic Enantioselective Reactions Using Chiral Magnesium Complexes 313 12.2.1 Chiral Magnesium-Catalyzed Diels–Alder and 1,3-Dipolar Cycloaddition Reactions 313 12.2.2 Chiral Magnesium-Catalyzed 1,4-Addition Reactions 315 12.2.3 Chiral Magnesium-Catalyzed Addition Reactions to Carbonyl Compounds 318 12.2.4 Chiral Magnesium-Catalyzed Addition Reactions with Imines 319 12.2.5 Chiral Magnesium-Catalyzed Ring-Opening Reactions of Epoxide and Aziridine 321 12.2.6 Chiral Magnesium-Catalyzed α-Functionalization Reactions of Carbonyl Compounds 323 12.2.7 Various Chiral Magnesium-Catalyzed Reactions 324 12.3 Catalytic Enantioselective Reactions Using Chiral Calcium Complexes 324 12.3.1 Chiral Calcium-Catalyzed Addition Reactions to Carbonyl Compounds 324 12.3.2 Chiral Calcium-Catalyzed 1,4-Addition Reactions 326 12.3.3 Chiral Calcium-Catalyzed Addition Reactions with Imines 331 12.3.4 Chiral Calcium-Catalyzed α-Functionalization Reactions with Carbonyl Compounds 333 12.3.5 Chiral Calcium-Catalyzed Cycloaddition Reactions 334 12.3.6 Chiral Calcium-Catalyzed Hydroamination Reactions 334 12.3.7 Chiral Calcium-Catalyzed Epoxidation Reactions 336 12.3.8 Chiral Calcium-Catalyzed Aziridine Ring-Opening Reaction 337 12.4 Catalytic Enantioselective Reactions Using Chiral Strontium Complexes 337 12.4.1 Chiral Strontium-Catalyzed 1,4-Addition Reactions 337 12.4.2 Chiral Strontium-Catalyzed Addition Reactions with Imines 338 12.4.3 Chiral Strontium-Catalyzed Oxime Formation 339 12.5 Catalytic Enantioselective Reactions Using Chiral Barium Complexes 339 12.5.1 Chiral Barium-Catalyzed Addition Reactions to Carbonyl Compounds and Imines 339 12.5.2 Chiral Barium-Catalyzed 1,4-Addition Reactions 340 12.5.3 Chiral Barium-Catalyzed Diels–Alder Reactions 341 12.6 Summary and Outlook 341 References 342 13 Miscellaneous Reactions 347Michael S. Hill 13.1 Introduction 347 13.2 Privileged Substrates and s-Block Reactivity 347 13.3 Reactivity with Multiply Bonded Substrates 351 13.3.1 Tishchenko Dimerization of Aldehydes 351 13.3.2 Trimerization of Organic Isocyanates 352 13.3.3 Hydroalkoxylation of Alkynyl Alcohols 353 13.3.4 Catalytic Isomerization and C–C Coupling with Terminal Alkynes 354 13.3.5 Activation and Deoxygenation of C—O Multiple Bonds 358 13.4 Single-Electron Transfer Steps in s-Block-Centered Catalysis 361 13.5 “Beyond” Hydrofunctionalization and Dehydrocoupling 363 13.6 Conclusions and Conjecture 365 References 367 Index 373

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Book SynopsisFrom the contents: Robert H Crabtree: Introduction and History. - Montserrat Diéguez, Oscar Pàmies and Carmen Claver: Iridium-catalysed hydrogenation using phosphorous ligands. - David H. Woodmansee and Andreas Pfaltz: Iridium Catalyzed Asymmetric Hydrogenation of Olefins with Chiral N,P and C,N Ligands. - Ourida Saidi and Jonathan M J Williams: Iridium-catalyzed Hydrogen Transfer Reactions. - John F. Bower and Michael J. Krische: Formation of C-C Bonds via Iridium Catalyzed Hydrogenation and Transfer Hydrogenation. - Jongwook Choi, Alan S. Goldman: Ir-Catalyzed Functionalization of CH Bonds. - Mark P. Pouy and John F. Hartwig: Iridium-Catalyzed Allylic Substitution. - Daniel Carmona and Luis A. Oro: Iridium-catalyzed 1.3-dipolar cycloadditions.Trade ReviewFrom the reviews:“Chapters cover a range of types of reactions … that are of strong interest in organic synthesis, and provide extensive up-to-date coverage of both the scope and limitations of the catalysts. … Overall, ‘Iridium Catalysis’ will serve as a useful up-to-date resource for both those entering the field and those experienced chemists who may not be aware of the advances that have been made. … Readers will be stimulated to find new applications for iridium in catalysis after they examine this book.” (William D. Jones, Platinum Metals Review, Vol. 56 (1), 2012)Table of ContentsRobert H Crabtree: Introduction and History.- Montserrat Diéguez, Oscar Pàmies and Carmen Claver: Iridium-catalysed hydrogenation using phosphorous ligands.- David H. Woodmansee and Andreas Pfaltz: Iridium Catalyzed Asymmetric Hydrogenation of Olefins with Chiral N,P and C,N Ligands.- Ourida Saidi and Jonathan M J Williams: Iridium-catalyzed Hydrogen Transfer Reactions.- John F. Bower and Michael J. Krische: Formation of C-C Bonds via Iridium Catalyzed Hydrogenation and Transfer Hydrogenation.- Jongwook Choi, Alan S. Goldman: Ir-Catalyzed Functionalization of CH Bonds.- Mark P. Pouy and John F. Hartwig: Iridium-Catalyzed Allylic Substitution.- Luis A. Oro and Daniel Carmona: Iridium-catalysed 1.3-dipolar cycloadditions.

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Book SynopsisThis book systematically describes the design and synthesis of MOF-related materials and the electrochemical energy storage-related research in the field of batteries. It starts with an introduction to the synthesis of MOF-based materials and various MOF derivatives, such as MOF-derived porous carbon and MOF-derived metal nanoparticles. This is followed by highlighting the interesting examples for electrochemical applications, illustrating recent advances in battery, supercapacitor, and water splitting. This book is interesting and useful to a wide readership in the various fields of chemical science, materials science, and engineering.Table of ContentsChapter 1 Nano/Micro MOF-based materials.- Chapter 2 MOF derivatives.- Chapter 3 Batteries.- Chapter 4 Supercapacitors.- Chapter 5 MOF-derived materials for energy conversion.- Chapter 6 Summary and Perspectives.

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