Oncology Books

Book SynopsisProstate cancer is the second leading cause of death in men and its progression is highly dependent on androgens and androgen receptors. However, even with treatment, eventually most prostate cancers progress. Studies of the mechanisms behind this progression leads to advances in treatments for androgen-related diseases. Our book discusses recent prostate cancer research, which includes the following topics: immunotherapy and chemotherapy; radiation, gene, hormonal, and androgen ablation therapies; basic mechanisms behind prostate cancer growth; how mechanisms can be used to treat prostate cancer; and research in newly developed mouse model systems.This book should be of interest as both a study guide and research reference to students, basic scientists, and clinicians.Table of ContentsHormonal Therapy for Prostate Cancer: Clinical and Experimental Evidence (H Miyamoto & C Chang); Immunotherapies for Prostate Cancer (K M Harsch et al.); Radiation Therapy and Hormonal Therapy for Prostate Cancer (R A Brasacchio); Gene Therapy for Prostate Cancer (J A Jimenez et al.); Chemotherapy for Prostate Cancer (S K Kulp et al.); Chemoprevention in Prostate Cancer (N Fujimoto); Neuroendocrine Differentiation and Androgen-Independence in Prostate Cancer (S J Desai et al.); Biology of Prostatic Acid Phosphatase and Prostate-Specific Antigen and Their Applications in Prostate Cancer (S Veeramani et al.); Epigenetics in Prostate Cancer (J A Karam et al.); Significance of 5 -Reductase in Prostate Cancer (J Shimazaki); Roles of Vitamin E in Prostate and Prostate Cancer (S Yeh et al.); Vitamin D and Prostate Cancer (Y-F Lee et al.); Functions of Estrogen Receptor in Prostate and Prostate Cancer (S Yeh et al.); Epidemiology of Prostate Cancer (A W Hsing & A Chokkalingam); Profiling Gene Expression Changes in Prostate Cancer (P S Nelson); Study of Androgen-Androgen Receptor Roles in Prostate Cancer Using Mice Lacking Functional Prostate Androgen Receptor (C-T Wu et al.); Capturing Signal Anomalies of Human Prostate Cancer into Mouse Models (H Wu et al.)

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Book SynopsisThis volume describes the elaborate surveillance systems and various DNA repair mechanisms that ensure accurate passage of genetic information onto daughter cells. In particular, it narrates how the cell cycle checkpoint and DNA repair machineries detect and restore DNA damages that are embedded in millions to billions of normal base pairs. The scope of the book ranges from biochemical analyses and structural details of DNA repair proteins, to integrative genomics and population-based studies. It provides a snapshot of current understanding about some of the major DNA repair pathways, including base-excision repair, nucleotide excision repair, mismatch repair, homologous recombination, and non-homologous end-joining as well as cell cycle checkpoints and translesion DNA synthesis. One of the particular emphases of the book is the link between inherited DNA repair deficiencies and susceptibility to cancer in the general population. For the first time, the book brings together a collection of review articles written by a group of active and laboratory-based investigators who have a clear understanding of the recent advances in the fields of DNA damage repair and genomic stability and their implications in carcinogenesis, new approaches in cancer therapy, and cancer prevention.Table of ContentsDNA Damage Sensing and Signaling (J L Wood & J Chen); Base Excision Repair (B Hang); Nucleotide Excision Repair (L Li); DNA Mismatch Repair: Biological Functions and Molecular Mechanisms (G-M Li); Mammalian Homologous Recombination Repair and Cancer Intervention (Z Shen & J A Nickoloff); Role of Non-Homologous End Joining in the Repair of DNA Double-Strand Breaks (S Burma et al.); A DNA-Damage Response Network of Fanconi Anemia and BRCA Proteins (R Guo & W Wang); Structure and Function of DNA Repair Proteins: Lesion Recognition (W Yang); DNA Damage Tolerance and Translesion Synthesis (F Xu et al.); Nucleases in DNA Repair, Replication and Recombination: Flap Endonuclease-1 as a Paradigm (P Singh & B Shen); Integrative Genomics and Epigenomics: Application in Cancer Research (M P Lee); Molecular Epidemiology of DNA Repair and Cancer Susceptibility -- A Review of Population-Based Studies (Z Hu et al.).

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Book SynopsisThis essential book is a compendium of papers written by an international team of world-renowned experts, who cover topics in their respective areas of expertise. Presenting the most up-to-date knowledge of hepatocellular carcinoma, it covers all topics — including those more controversial ones — in this rapidly advancing field, from epidemiology to prevention, from molecular biology to gross pathology, from screening to atypical presentation, from diagnosis to treatment, and from assessment to choice of appropriate treatment. This volume is therefore an important contribution to the field of hepatocellular carcinoma.Table of ContentsEpidemiology; Assessment of Liver Function; Prevention; Screening; Tumor Markers; Diagnostic Imaging; Pathology; Molecular Aspects; Staging; Selection of Patients for Liver Resection; Intraoperative Ultrasound; Intrahepatic Glissonian Approach; Laparoscopic Liver Resection; Techniques of Liver Transection; Cryosurgery; Local Ablative Therapy; Systemic Therapy; Palliative Care; and other papers.

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Book SynopsisCancer treatment has enjoyed half a century of healthy development, relying mainly on surgery, cytotoxic therapy and radiation. Achievements and successes are well reflected in the longer survival period and better quality of life. Nonetheless, cancer still spreads locally, recurs, metastasizes and remains one of the top killers.Instead of concentrating on cancer removal, it has become obvious that supportive measures are also important. These include the means to improve quality of life during treatment and to contain tumor growth. To this end, herbal medicine appears to offer holistic support via as yet unknown pathways.This volume reveals the practice of cancer treatment using herbs from all over the world, including China, India and Japan. It provides comprehensive information about the herbs commonly used, the logic of using the herbs, some of the mechanisms of action and other means of palliative treatment. While cancer victims have a thirst for choosing their own supplementary treatment, health providers have a duty to explain to them the justifications and the options.Table of ContentsThe Scientific Basis of Chinese Medicine and Cancer Care: A Western Medicine Perspective (S M Sagar & R Wong); Risk Management of Complementary Alternative Medicines in Cancer (U Werneke); Complementary Therapies for Cancer Patients (B R Cassileth et al.); Functional Magnetic Resonance Imaging Studies of Acupuncture (G Deng & B Cassileth); Recent Status and Outlook of Traditional Chinese Medicine in Cancer Treatment (D-H Zhou); Positive Findings about Herb and Natural Product Action on Cancer (M J Montbriand); Kampo Treatment for Cancer (K Watanabe); Chinese Medicine and Cancer Treatment: A General Review and Hong Kong Experience (P-C Leung); Complementary Approaches to Cancer in Italy (R W Moss); Ethnopharmacology Approaches for Botanical Immunomodulators and Chemoprotectants in Cancer Therapy (P Bhushan & G Manish); Advancements of Ayurveda in Cancer Management with Special Focus on Hepatocellular Carcinoma (P Balachandran); New Approach for Evaluating the Anti-Breast Cancer Activity of Traditional Chinese Medicine (J M Pezzuto et al.); Clinical Evaluation of An Herbal Formula Decoction in Treating Non-Small Cell Lung Cancer by Various Rating Scales (J You & Z-M Shi); Mechanistic Studies on Combination of Phytochemicals and Synthetic Drugs as Anticancer Agents (S HemaIswarya and M Doble); Bioactive Polysaccharides from TCM Herbs as Anticancer Adjuvants (R Chang).

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Book SynopsisDNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology.Table of ContentsDNA Microarray Technique; Current Analytical Methods of DNA Microarray Data; Advantages and Disadvantages; Current Application of DNA Microarray Technique in Medicine; A Novel Method for DNA Microarray Data Analysis; Future Directions.

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Book SynopsisThe fibroblast growth factor (FGF) family of ligands and the corresponding family of FGF receptor tyrosine kinases comprise one of the most versatile and diverse growth factor signaling families in vertebrates, found virtually in every tissue and cell type where they regulate metabolic and physiologic function, maintain tissue homeostasis, and mediate injury response, tissue repair, and regeneration. As a result, FGFs play critical roles in a wide variety of normal biological and abnormalities in FGF signaling can lead to a variety of disease states from developmental malformations, to atherosclerosis, pulmonary hypertension and cancer among many others. A thorough understanding of this system is necessary for critical insights into both normal and disease biology and is essential to development of rationale therapeutic strategies aimed at treatment of FGF-dependent diseases states.Recent years have seen advances in our understanding of FGFs role in endothelial and, more general, vascular biology, the subject of this book. In particular, FGFs have been implicated in the maintenance of vascular homeostasis and control of blood vessel permeability while aberrant FGF signaling has been shown to be central to the development of pulmonary hypertension, and endothelial-to-mesenchymal transition, a process implicated in the development of atherosclerosis. Finally, FGFs ability to stimulate blood vessel growth has been explored in therapeutic angiogenesis approaches.With this in mind, the present monograph is structured to provide comprehensive information to a reader interested in FGFs in general and vascular biology in particular. To this end, we explore everything from the structure and signaling of FGFs and their receptors (Chapters 1, 2 and 3) to their role in the regulation of vascular homeostasis (Chapter 4) and cardiovascular diseases (Chapters 5 and 6). We then address new developments in FGF therapeutics (chapter 7) and explore FGF biology in the epithelium (Chapter 8) thereby providing a complete analysis of this growth factor family biology in two closely related but distinctly different environments — endothelium and epithelium. Finally, we examine FGF biology in eye disease and in cancer.It is our hope that this comprehensive treatment of FGF vascular biology and its application will provide the reader with the accurate and timely summary of this rapidly moving field.

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Book SynopsisTumors often start out as a benign growth, but gradually progress toward the malignant stage over a relatively long period of time. Tumor progression results from accumulated genetic mutations and inheritable epigenetic modifications that enable clonal evolution and selection of new clonal populations of tumor cells with aggressive characteristics including metastasis and therapy resistance. Increasing amounts of experimental evidence suggests that tumor microenvironment play a significant role in directing clonal evolution and determining clonal cell fate, which eventually leads to emergence of malignant tumor cell clones. Hypoxia is the most commonly observed feature of tumor microenvironment. Tumor hypoxia is significantly associated with malignant progression and predicts poor patient outcomes. This book provides detailed and up-to-date treaties on the role of hypoxia as a major driving force in tumor microenvironment to elicit cellular adaptation and clonal selection via genetic mutations and epigenetic modifications, to facilitate cancer stem cell maintenance, to enhance metastasis, to augment therapy resistance, and to evade immune surveillance.

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Book SynopsisThis unique book deals with both inflammation and cancer in a single source of publication. They are seldom grouped together although it has been known that both diseases are closely associated, particularly in the gastrointestinal tract and liver. As the book touches on two such major areas of diseases in humans, it should be of interest to a wider audience of researchers and readers. It is noted that the book combines the effort of both basic scientists and clinicians from different countries with extensive experiences in molecular biology and clinical practice to unveil the most updated picture of the pathogenesis and therapeutic strategies in the treatment of inflammation and cancer in the digestive tract. In this regard, potential pathogenic modulators and also therapeutic options are widely discussed. These types of information would definitely broaden our knowledge in better understanding these diseases.

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Book SynopsisDevelopment of cancer, a dreadful disease of mankind, is a multi-stage process involving numerous molecular alterations at both genomic and proteomic levels. Immense research for the past several decades in the field of cancer identified many such mutations and their role in carcinogenesis. Concept of 'fusion genes' seeded way back in 20th century has now grown into a new field of cancer research. However, there is a lack of knowledge among scientists about these fusion genes and their importance in cancer, which can be mainly attributed to unavailability of a comprehensive book on this topic. Therefore, this book is first of its kind and aims at giving a detailed idea on the formation of gene fusions and their importance in the development and progression of cancer; techniques to identify novel gene fusions; and therapeutics available to target various fusion proteins and their impact in cancer therapy by compiling the information from the literature available till date.

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Book SynopsisAdvances in cancer research have grown exponentially in recent decades. What we now know about the disease owes a lot to breakthroughs in science and technology. Cancer researchers have had to solve increasingly difficult problems with methods that were unimaginable just a few years ago, and new generations of researchers have to be trained to face these challenges.One important aspect of their training is the framing of social, economic and cultural changes of the human population. Despite having state-of-the-art technology and specializations, researchers are still required to think faster than ever before, making new discoveries fit the practical situation of each type of cancer. This book discusses a number of topics that address these challenges and the origins of cancer research from a cultural and historical perspective.

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Book SynopsisDespite the significant advances in cancer therapy made through constant evaluation and analysis of treatment aftereffects, the disease still remains one of the foremost causes of mortality worldwide killing more than 12 million people annually. The prime reason behind the failure of conventional chemotherapeutics which are used as the chief regimen in the comprehensive treatment of cancers is the development of chemoresistance. It can be either intrinsic or acquired and is primarily mediated via different key regulators like MDR, MAPK, NF-κB, PI3K/Akt, Wnt signaling pathways etc. Thus, agents which can target these regulatory elements or pathways and in turn sensitize cancer cells to chemotherapy holds immense prospect. However, there is barely such comprehensive work available in scientific literature that explains how chemosensitization of cancer cells functions using different drug combinations and exhibit synergism. This book provides a detailed description of chemoresistance and chemosensitization, targets for chemosensitization and various approaches adapted in the process of chemosensitization. Furthermore, the book explicates the role of various chemosensitizers, both natural and synthetic in sensitizing cancer cells and also details the current research findings on chemosensitization of different cancer types in both pre-clinical and clinical settings.

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Book SynopsisSystems biology combines computational and experimental approaches to analyze complex biological systems and focuses on understanding functional activities from a systems-wide perspective. It provides an iterative process of experimental measurements, data analysis, and computational simulation to model biological behavior. This book provides explained protocols for high-throughput experiments and computational analysis procedures central to cancer systems biology research and education. Readers will learn how to generate and analyze high-throughput data, therapeutic target protein structure modeling and docking simulation for drug discovery. This is the first practical guide for students and scientists who wish to become systems biologists or utilize the approach for cancer research.

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Book SynopsisAs chemical exposures and cancer rates increase worldwide, there is a need for students, researchers, public health professionals, and physicians to understand the mechanisms connecting exposure with human cancer risk. This new book is an essential reference, as well as introduction to the field of chemical carcinogenesis, with particular focus on DNA damage as a critical link between exposure and disease, and emphasis on biomarkers associated with cancer risk in humans. In addition to DNA damage, related topics covered include metabolism of selected chemical carcinogens, exposure-induced epigenetic changes, cancer-associated mutations and reduction of DNA damage and cancer risk by chemoprevention. The book is designed to be a comprehensive guide to basic principles, a teaching tool for academics, and a map for the development of protective mechanisms to reduce human cancer risk.

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Book SynopsisThis narrative of a cancer researcher spans a period in which biomedicine research has been so revolutionary. The educational background and socioeconomic circumstances of the author make the story unique, shedding light on many important intellectual achievements. The author also provides an insightful view on how decisions at the upper echelon of scientific institutions affect cancer researchers. The vivid account of scientific discovery and intellectual evolution provides a fine example for the next generation of cancer researchers.

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Book SynopsisPanic is the common initial reaction from a person diagnosed with cancer. Most patients, with a lack of knowledge about the nature of cancer and the treatment options, become anxious to learn about cancer and how to overcome the notorious disease.However, it is not easy for cancer patients to gain a comprehensive understanding of the scientific and medical knowledge about cancer. The main reason is that the information needed is scattered in many different resources, and the information is complex and difficult for ordinary people to understand.In an attempt to help ordinary people understand cancer and its medical science, the author has written this book in an easy-to-understand style, so that patients can manage cancer more effectively in their life time.Providing information for patients to understand the why, how, and what with each step of treatment plan, as well as a realistic range of possible outcomes, is very important. Information can help patients reduce anxiety and give patients a greater sense of ownership in their treatment process. The sense of ownership is imperative to growing a positive attitude for patients fighting cancer.This book is a one-stop shop, easy-to-understand guidebook for cancer patients to understand:

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Book SynopsisPanic is the common initial reaction from a person diagnosed with cancer. Most patients, with a lack of knowledge about the nature of cancer and the treatment options, become anxious to learn about cancer and how to overcome the notorious disease.However, it is not easy for cancer patients to gain a comprehensive understanding of the scientific and medical knowledge about cancer. The main reason is that the information needed is scattered in many different resources, and the information is complex and difficult for ordinary people to understand.In an attempt to help ordinary people understand cancer and its medical science, the author has written this book in an easy-to-understand style, so that patients can manage cancer more effectively in their life time.Providing information for patients to understand the why, how, and what with each step of treatment plan, as well as a realistic range of possible outcomes, is very important. Information can help patients reduce anxiety and give patients a greater sense of ownership in their treatment process. The sense of ownership is imperative to growing a positive attitude for patients fighting cancer.This book is a one-stop shop, easy-to-understand guidebook for cancer patients to understand:

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Book SynopsisTriple-negative breast cancer (TNBC) represents a challenge clinically due to the lack of actionable targets coupled with an aggressive disease course and a worse prognosis compared to other breast cancer subtypes. This book covers aspects of TNBC ranging from epidemiology, biology, molecular classification, to currently available and potentially new therapeutic options for TNBC. This book contains a range of recommended resources, including recent reviews, schematic illustrations, and information for patients with TNBC. Individuals including researchers and educators, practitioners, pharmaceutical professionals, patients as well as their family members will find this book useful.

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Book SynopsisCancer research has progressed enormously in recent years. This review volume will address recent findings in the area of T-cell therapy for cancer, including use of tumour infiltrating lymphocytes (TILs) as a therapy for melanoma, choice of target antigens, advances in engineered receptors, methods of gene transfer to T cells, review of cell processing methods and clinical trial design. Written by leadings scientists in the field, this up-to-date review on cancer research will be an important reference source to the researchers and healthcare professionals in the field.Table of ContentsChallenges of T-Cell Therapy; Non-modified T-Cells; Gene Transfer into T-Cells; TCR Engineered T-Cells: An Introductory/Scientific Overview; Antibody Based Engineered T-Cell Receptors; T-Cell Engineering and Expansion - GMP Issues; Clinical Trial Design;

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Book SynopsisSignificant progress in engineering has allowed the production of devices that can optically detect, differentiate and treat surface or near-surface cancers. The ability to differentiate cancerous from non-cancerous tissue in vitro using light represents a potentially significant advance in patient care, eliminating needless repeat procedures. With the help of advanced optical technologies, clinicians are able to identify cancers earlier, determine surgical margins at the time of surgery, and monitor treatment results without using expensive and insensitive imaging.This volume describes the state-of-the-art optical detection technologies in varying stages of cancer development. Written by an international panel of basic researchers, engineers and clinicians, the book is designed to give an up-to-date overview of the most recent advances for researchers and medical professionals who are interested in the biophotonic detection of cancer.Table of ContentsIntroduction (T Steele & A Meyers); Optical Coherence Tomography in Oral Cancer (P W Smith); Markers and Nanomarkers (E Gibson); PDT Techniques (Z Huang); Raman Spectroscopy (T Lei); Fluorescence (C Arens); In Vivo Multiphoton Microscopy (N Barry); Light Propagation in Tissue (R Tagg); OCT in Laryngeal Cancer (M Kraft); Optical Detection of Cancer: Feasibility, Challenges, and Future (P Verahera); Fluorescence Imaging and Spectroscopy of Oral and Oropharyngeal Cancers (C Betz); Optical Detection of Bile Duct Cancer (Y Chen);

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Book SynopsisThis book effectively summarizes our knowledge of recent advances in prostate cancer. It focuses on our state-of-the-art understanding of risk factors, prevention, detection, prognosis and treatment of prostate cancer and identifies basic science findings that are being translated into clinical practice. In addition, the book singles out key areas of research that have potential for clinical translation. Both basic scientists and clinicians will be invited to provide up-to-date reviews in each area of prostate cancer.During the last decade the pace of clinical discovery and the scientific advances in prostate cancer have been very rapid. For instance, currently there are more than 100 drugs in the pharmaceutical pipeline that have the potential for clinical management of prostate cancer. Therefore, it has been very difficult for clinicians and basic scientists to keep pace with the field as a whole. Recently, some of these discoveries are already having an impact on clinical practice. For example, the discovery of the androgen receptor gene amplification in prostate cancer has led to the development of a “super-antiandrogen”, which is being tested in clinical trials. Also, recent knowledge of androgen synthesis in prostate cancer cells has led to clinical trials with steroid-metabolism inhibitors. Finally, robotic surgery has also dramatically changed clinical practice. Thus, this important book serves to provide readers with a one-stop overview of the field of prostate cancer research and its translation into the clinical arena.Table of ContentsPathology of Prostate (L True); Genetic Basis for Prostate Cancer (S Loeb & W B Isaacs); Androgen Receptor Converts from a Growth Suppressor in the Normal Prostate to an Oncogene in Prostate Cancer (D J Vander Griend & J T Isaacs); Etiology: Role of ETS Factor Gene Fusions (J Wang & M Ittmann); Role of Inflammation in Prostate Cancer (W Nelson & S Kimmel); Tumor Biology (E Benedettini et al.); The Androgen Receptor (K Datta et al.); Intracrine Synthesis of Androgens by Prostate Cancer in Response to Androgen Deprivation Therapy (J L Mohler et al.); Genetically Engineered Mouse Models in Prostate Cancer Research (F Wang et al.); Detection of Prostate Cancer: PSA (H Lilja & F Schroeder); Imaging of Prostate Cancer (E Mena et al.); Treatment of Prostate Cancer with Radiation (A Diaz & A Pollack); Treatment of Prostate Cancer: Surgery (V P Laudone et al.); Treatment of Prostate Cancer - Hormonal Therapy (A Elfiky & P Kantoff); Chemotherapy for Castration-Resistant Prostate Cancer (G Iyer et al.); Novel Therapeutic Approaches to Advanced Prostate Cancer (M K Tollefson & E D Kwon); Prevention of Prostate Cancer (I Thompson).

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Book SynopsisCryosurgery is a surgical technique that employs freezing to destroy undesirable tissue. From as early as 3500 BC, there is evidence for the use of cold in medicine for the treatment of infected wounds of the chest, fracture of the skull and various injuries. However, the history of “modern” cryosurgery is relatively short and is closely intertwined with the development in low temperature physics, engineering, and instrumentation during the last century.From the early 21st century, advanced helium-based cryosurgery has been applied worldwide. More than ten thousand patients with malignant and benign tumors have received cryosurgery. It is specially noted that in most cases cryosurgery, as a mini-invasive ablation technique, was performed with percutaneous approach under guidance of CT or ultrasound. Cryosurgery is now one of the more popular techniques in China, with nearly 6000 cases of tumors receiving cryosurgery in the author's institution alone. This book summarizes the experimental and clinical experience and practice of cryosurgery, and describes the basics of cryosurgery and its use in the treatment of various tumors.Table of ContentsGeneral Information: History, Development and Future of Cryosurgery; Basics of Cryosurgery: Apparatus and Principle of Cryosurgery; Mechanism of Cryosurgery; Cryosurgery and Immunity; Cryosurgery and Chemotherapy; Imaging Techniques in Cryosurgery; Indication and General Evaluation of Cryosurgery for Tumors; Effectiveness of Cryosurgery for Tumors; Safety of Cryosurgery for Tumors; Cryosurgery for Chest Tumors: The Feasibility and Safety of Percutaneous Cryosurgery for Experimental Lung Model; Cryosurgery for Lung Cancer; Combination of Percutaneous Cryosurgery with Photodynamic Therapy for Lung Cancer; Combination of Percutaneous Cryosurgery with Radioactive Seed Brachytherapy for Lung Cancer; Cryosurgery for Cardiac and Pericardiac Tumors; Cryosurgery for Breast Cancer; Cryosurgery for Breast Fibriadenoma; Cryosurgery for Other Chest Tumors; Cryosurgery for Abdominal Tumors: Cryosurgery for Hapatocellular Carcinoma; Cryosurgery for Metastatic Hepatic Carcinoma; Combination of Cryosurgery with Transarterial Embolization for Liver Cancer; Combination of Cryosurgery with Other Ablative Techniques for Liver Cancer; Cryosurgery for Focal Nodular Hyperplasia; Feasibility and Safety of Cryosurgery for Experimental Pancreatic Model; Cryosurgery for Locally Advanced Pancreatic Cancer; Cryosurgery for Renal Tumors; Cryosurgery for Cancer of Adrenal Gland; Cryosurgery for Pelvic Tumors; Cryosurgery for Malignant Tumors of Pelvis: Cryosurgery for Cervical Intraepithelial Neoplasia; Cryosurgery for Uterine Tumor; Cryosurgery for Functional Uterine Bleeding; Cryosurgery for Prostate Cancer; Cryosurgery for Tumors of Head, Face and Neck: Cryosurgery for Head and Neck Tumors; Cryosurgery for Thyroid Tumor; Cryosurgery for Brain Tumor; Cryosurgery for External Tumors and Lymphomas: Cryosurgery for Non-Melanoma Skin Tumors; Cryosurgery for Melanoma; Cryosurgery for Advanced External Tumors; Cryosurgery for Lymphoma; Cryosurgery for Soft Tissue and Bone Tumors: Cryosurgery for Soft Tissue Tumors; Cryosurgery for Bone Tumors.

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Book SynopsisWith recent clinical advances, millions of people survive many years after a cancer diagnosis. And while their physicians deliver conventional, evidence-based therapies to treat the cancer, sometimes the cancer patient and his or her symptoms are not treated with equal skill.To manage their physical and emotional symptoms and promote health and well-being, most cancer patients and survivors use complementary therapies: Naturopathy, Ayurveda, herbalism, homeopathy, hypnosis, yoga, acupuncture, music therapy, macrobiotics, chelation therapy, colonics, hydrotherapy and many, many more. But … are they safe? Are they effective? What problems do they address? What are the risks? When can they help?This unique and comprehensive book guides the way through the often confusing maze of complementary and alternative therapies promoted to cancer patients and survivors. The functions, benefits, backgrounds and risks are clearly presented. Learning when, if and how to use them provides medical professionals, cancer patients and survivors with the information they need to better control the symptoms and side effects of cancer and its treatment. Unfortunately, using some of these therapies without this expert guidance can lead to medical complications, or worse.The Complete Guide to Complementary Therapies in Cancer Care is an invaluable resource in making educated health care decisions for managing life during and after cancer. Through the wise and informed use of these approaches, cancer patients — whether just-diagnosed, during treatment or throughout Survivership are better able to manage the physical and emotional stresses that accompany cancer, leading to symptom control and improved quality of life.Table of ContentsAncient Routes to Health and Spiritual Fulfillment; Dietary and Herbal Remedies; Mind-Body Therapies; Gaining Strength through Bodywork; Enhancing Well-Being through the Senses; AlternativeA" (Unproven or Disproved) Treatments Taken Internally; AlternativeA" External Energy Therapies.

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Book SynopsisThe book focuses on two concurrent experimental therapies in cancer treatment known as boron neutron capture therapy (BNCT) and gadolinium neutron capture therapy (GdNCT) using a variety of boron- and gadolinium-based compounds. Some of the gadolinium compounds serve the dual purpose as being MRI contrast agents and GdNCT agents. The book describes why BNCT & GdNCT were not at the forefront of the clinical trials during the past seven to eight decades since the discovery of neutrons by John Chadwick in 1932 and how the latest development in the synthesis of target boron- and gadolinium-based drugs has turned the area into the hottest one worthy of further investigation with the new clinical trials in the USA and elsewhere.Table of ContentsIntroduction; Principles of Neutron Capture Therapy; Major NCT Drug Prototypes; Boron Compounds-Based BNCT Agents; Neutron Sources for NCT; NCT Dosimetry and Treatment Planning; Selected in vitro and in vivo Studies; Clinical Trials; Summary; The Future of NCT; Appendix: Clinical State of BNCT by US Department of Energy (DOE) as of 1997; Acknowledgments; References.

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Book SynopsisInflammation and cancer are two major disorders that cause huge concerns in our society. However, what one may not know is that both diseases are closely associated and, in particular, both occur in the gastrointestinal tract and liver. This book describes the mechanics of how inflammation can progress to cancer in these organs. The authors in this book comprehensively discuss the different biomarkers for early diagnosis, and current therapeutic treatments for these diseases. All of these would allow us to better understand the pathogenesis of both diseases. As such, this book provides comprehensive information concerning the interrelationship between inflammation and cancer in a cohesive manner, and the information derived would benefit not only basic scientists but also clinicians who are working in these fields.Table of ContentsPathogenic Mechanisms of Inflammation and Cancer; Hepatitis; Inflammatory Bowel Disease; Colorectal Cancer; Mediators in Inflammation and Cancer; Interventional Radiology; Tumor Markers.

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Book SynopsisThis invaluable manual provides a practical overview of the field of gynecologic oncology. Focusing on clinical aspects of the specialty, it provides hands-on guidance for those caring for patients with ovarian, cervical, uterine, and lower genital tract cancers. It describes the current epidemiology, pathophysiology, presentation, diagnosis, and multimodality management of the most common gynecologic malignancies. Chapters are also devoted to radiation and chemotherapy, as well as symptom management. The book is designed for quick reference.Table of ContentsChemotherapy; Radiation Therapy; Preinvasive Disease; Vulvar Cancer; Vaginal Cancer; Cervical Cancer; Endometrial Cancer; Uterine Sarcoma; Ovarian Cancer; Non-Epithelial Ovarian Cancer; Gestational Trophoblastic Disease; Emergencies in Gynecologic Oncology; Supportive Care.

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Book SynopsisIn this volume, a team of internationally recognized experts provide an in-depth description of therapeutic biomarkers across a broad area of cancer research and oncology. With a wealth of information to specific therapies, each chapter focuses on a class of targeted chemotherapy agents. The book describes established and evolving diagnostic tests for therapeutic biomarkers that predict benefit, response, resistance, or drug side effects from specific therapeutic interventions. This volume is an essential handbook for health professionals and scientists researching current applicable biomarkers in oncology.Table of ContentsOverview: Therapeutic Biomarkers in Cancer. Statistical Considerations in the Development and Evaluation of Therapeutic Biomarkers in Cancer. Role of Biomarkers in Clinical Development of New Cancer Therapies. HER2 as a Prognostic and Predictive Biomarker in Cancer. Hormone Receptors and Endocrine Therapy in Breast Cancer. Predictive Biomarkers for Epidermal Growth Factor Receptor (EGFR) Agents in Non-Small Cell Lung Cancer. Markers of Sensitivity and Resistance to EGFR Inhibitors in Colorectal Cancer. Targeting BCR-ABL for Molecular Therapy of Chronic Myelogenous Leukemia. Gastrointestinal Stromal Tumors (GISTs): From Molecular Pathogenesis to Therapy. PML/RARa Fusion Gene and Response to Retinoic Acid and Arsenic Trioxide Treatment. Dihydropyrimidine Dehydrogenase Deficiency and 5-Fluouracil Toxicity. UGT1A1 Polymorphisms and Mutations Lead to Irinotecan-Induced Toxicity. The 21-Gene Recurrence Score and Benefit of Chemotherapy in Estrogen Receptor-Positive Breast Cancer. MammaPrint for Individualized Recurrence Risk Assessment and Treatment Recommendations for Early-Stage Breast Cancer Patients. BRCA mutation and PARP Inhibitors. EML4-ALK Fusion Gene and Therapy with ALK-targeted Agents in Non-Small Cell Lung Cancer. BRAF-Targeted Therapy in Metastatic Melanoma.

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Book SynopsisSignificant advances made by Western medicine in the treatment of cancer are well-documented, but little has been written in English on complementary holistic treatment with Chinese medical methods that manage its symptoms and ameliorate the side effects of surgery, chemotherapy or radiotherapy. This book explains the complementary approach using cases from the medical files of Professor Rencun Yu, who was trained in Western medical oncology but also practices Chinese medicine. In addition, introductory chapters explain the basic principles of Chinese medicine, while other chapters cover the prevention of cancers through appropriate nutrition and living habits. The book should command the attention of medical professionals as well as the layperson interested in preventing and understanding the illness.There is no equivalent book in English that so skillfully combines an introduction to Chinese medical principles and cancer management for the general reader with detailed clinical studies of the crucial complementary role played by Chinese medicine in Western treatments for cancer patients.Table of ContentsIntroduction; Principles of Diagnosis and Therapy in TCM; Chinese Herbs and Prescriptions; Cancer Prevention and Treatment Using TCM; Major Forms of Cancer and Case Studies; Diet, Exercise and Health Cultivation.

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Book SynopsisCancers are on the rise across the world. Except for viral-based cancers, overall cancers are diseases that may be preventable. This book looks at the many levels of determined, probable, and possible causation for several common cancers. These causes include realities found in culture, anthropology, sociology, politics, the environment, agriculture and food, beliefs, and the modern lifestyle. These realities are filtered through the perennial science of Chinese medicine — an ecological system of knowing and understanding the human body as it relates to the world around us.The book covers lung, colorectal, breast, prostate, and virally-caused cancers. It interweaves conventional medical knowledge of these cancers with modern realities of everyday life we all live, and with Chinese medicine interpretations and strategies for treating probable pre-cancerous conditions. This makes it a book that is useful for the practitioner of Chinese medicine. It is also useful for the patient suffering a cancer diagnosis in terms of survivorship and for other medical practitioners who wish to understand how integrated care for cancerous diseases and conditions may relate to Chinese medicine and prevention.The final chapters of the book are dedicated to finding answers for a cure for cancer through making connections between how we live, what we believe, the environment we are creating based on those beliefs, and the social and political mechanisms we now have in place that keep us from change and, therefore, from the cure for cancer.Table of ContentsWater: The San Jiao and The Lowest Common Denominator; Air: The Medium is the Messenger - Lung Cancer; Earth: The Soil of life - Colorectal Cancer; Yin and Qi - Breast Cancer; Yin and Yang - Prostate Cancer; Fire - Viral Cancers; Epigenetics and the Source Qi; The Geology of Hope; Connections.

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Book SynopsisCancers are on the rise across the world. Except for viral-based cancers, overall cancers are diseases that may be preventable. This book looks at the many levels of determined, probable, and possible causation for several common cancers. These causes include realities found in culture, anthropology, sociology, politics, the environment, agriculture and food, beliefs, and the modern lifestyle. These realities are filtered through the perennial science of Chinese medicine — an ecological system of knowing and understanding the human body as it relates to the world around us.The book covers lung, colorectal, breast, prostate, and virally-caused cancers. It interweaves conventional medical knowledge of these cancers with modern realities of everyday life we all live, and with Chinese medicine interpretations and strategies for treating probable pre-cancerous conditions. This makes it a book that is useful for the practitioner of Chinese medicine. It is also useful for the patient suffering a cancer diagnosis in terms of survivorship and for other medical practitioners who wish to understand how integrated care for cancerous diseases and conditions may relate to Chinese medicine and prevention.The final chapters of the book are dedicated to finding answers for a cure for cancer through making connections between how we live, what we believe, the environment we are creating based on those beliefs, and the social and political mechanisms we now have in place that keep us from change and, therefore, from the cure for cancer.Table of ContentsWater: The San Jiao and The Lowest Common Denominator; Air: The Medium is the Messenger - Lung Cancer; Earth: The Soil of life - Colorectal Cancer; Yin and Qi - Breast Cancer; Yin and Yang - Prostate Cancer; Fire - Viral Cancers; Epigenetics and the Source Qi; The Geology of Hope; Connections.

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Book SynopsisAn estimated 12.6 million people are diagnosed with cancer every year and 7.6 million people die of the disease annually. Numerous lines of evidence suggest that lifestyle and nutrition play an important role in cancer development. As for nutrition, diets that are rich in fruits and vegetables have been shown to lower the risk of cancer incidence. In addition, several phytochemicals that are present in fruits and vegetables have been scientifically established to have properties that can prevent and treat this malevolent disease.The primary aim of the book is to educate the public about the benefits of fruits and vegetables as they relate to cancer and their potential to contribute to the possibility of a cancer-free life. The active ingredients and modes of actions of fruits and vegetables are also discussed, along with their chemo-preventive aspects.This clearly written, comprehensive guide explains the properties of these natural foods and substances on a cancer-by-cancer basis. Thus, this book not only informs the general public about the anticancer properties of fruits and vegetables but also provides a valuable reference for scientists and other professionals working in this area.Table of ContentsFruits and Vegetables and Their Active Components; Cancer Chemopreventive and Therapeutic Potential of Fruits and Vegetables Against Breast Cancer; Colon Cancer; Head and Neck Cancer; Liver Cancer; Lung Cancer; Pancreatic Cancer; Prostate Cancer; Stomach Cancer and Other Commonly Occurring Cancers in Humans; Mechanism of Action of the Active Components of Fruits and Vegetables.

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Book SynopsisCancer research is at a crossroads. Traditionally, cancer has been thought of as a disease of gene mutation, where the stepwise accumulation of cancer gene mutations is the key, and the identification of common gene mutations has been considered to be essential for diagnosis and treatment. Despite extensive research efforts and accumulated knowledge on cancer genes and pathways, the clinical benefits of this traditional approach have been limited. Recently, cancer genome sequencing has revealed an extensive amount of genetic heterogeneity where the long-expected common mutation drivers have been difficult, if not impossible, to identify. These realities ultimately challenge the conceptual framework of current cancer biology.This book introduces a new concept of genome theory of cancer evolution, in an attempt to unify the field. Many important and representative, but often confusing, questions and paradoxes are critically analyzed. By comparing gene- and genome-based theories, the hidden flaws of many popular viewpoints are addressed. This discussion is intended to initiate a much-needed critical re-evaluation of current cancer research.Table of ContentsGene Mutation Theory vs. Genome Theory; Cancer Genome Landscape: The Untold Story of Cancer Genome Sequencing; Lottery Principle: The Gene, Genome, Environment, and the Perfect Storm; Examples of Popular but Flawed Concepts about Cancer; Why "Noise" is Important in Cancer Evolution; Why Basic Research Fails to Bridge the Gap with the Clinic World; Do Different Cancers Represent Different Species?; Challenging Current Molecular Methodologies for Cancer Research.

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Book SynopsisThe book aims to provide an introduction to mathematical models that describe the dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for advanced undergraduate or graduate courses, and also serves as a reference book for researchers. The book has a strong evolutionary component and reflects the viewpoint that cancer can be understood rationally through a combination of mathematical and biological tools. It can be used both by mathematicians and biologists. Mathematically, the book starts with relatively simple ordinary differential equation models, and subsequently explores more complex stochastic and spatial models. Biologically, the book starts with explorations of the basic dynamics of tumor growth, including competitive interactions among cells, and subsequently moves on to the evolutionary dynamics of cancer cells, including scenarios of cancer initiation, progression, and treatment. The book finishes with a discussion of advanced topics, which describe how some of the mathematical concepts can be used to gain insights into a variety of questions, such as epigenetics, telomeres, gene therapy, and social interactions of cancer cells.Table of ContentsTeaching Guide; Cancer and Somatic Evolution; Mathematical Modeling of Tumorigenesis; Basic Growth Dynamics and Deterministic Models: Single Species Growth; Two Species Competition Dynamics; Competition Between Genetically Stable and Unstable Cells; Chromosomal Instability and Tumor Growth; Angiogenesis Inhibitors, Promoters, and Spatial Growth; Evolutionary Dynamics and Stochastic Models: Evolutionary Dynamics of Tumor Initiation Through Oncogenes: The Gain-of-Function Model; Evolutionary Dynamics of Tumor Initiation Through Tumor-Suppressor Genes: The Loss-of-Function Model and Stochastic Tunneling; Microsatellite and Chromosomal Instability in Sporadic and Familial Cancers; Evolutionary Dynamics in Hierarchical Populations; Spatial Evolutionary Dynamics of Tumor Initiation; Complex Tumor Dynamics in Space; Stochastic Modeling of Cellular Growth, Treatment, and Resistance Generation; Evolutionary Dynamics of Drug Resistance in Chronic Myeloid Leukemia; Advanced Topics: Evolutionary Dynamics of Stem-Cell Driven Tumor Growth; Tumor Growth Kinetics and Disease Progression; Epigenetic Changes and The Rate of DNA Methylation; Telomeres and Cancer Protection; Gene Therapy and Oncolytic Virus Therapy; Immune Responses, Tumors Growth, and Therapies; Towards Higher Complexities: Social Interactions.

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Book SynopsisGastrointestinal Malignancies: New Innovative Diagnostics and Treatment summarizes new advantages in the diagnosis and treatment of gastrointestinal malignancies, thereby providing the most current and up-to-date knowledge on gastrointestinal malignancies to medical students, gastroenterologists, general surgeons, oncologic surgeons, and oncologists.This book will feature the progresses made on treatment and diagnosis of gastrointestinal malignancies in the last ten years and provides the most current diagnostic and therapeutic modalities to the readers. The book will be an excellent reference tool for physicians and surgeons working in the field of gastrointestinal malignancies.Editors of the book are experts from both the western and eastern parts of the world.Table of ContentsEpidemiology of Gastrointestinal Malignancies; Molecular Biology and Genetics of Gastrointestinal Malignancies; Prevention of Gastrointestinal Malignancies; Imaging in Gastrointestinal Malignancies; Nutritional Support of Patients with Gastrointestinal Malignancies; Palliative Care for Patients with Advanced Stage of Gastrointestinal Malignancies; Endoscopic Diagnosis and Treatment of Earlier Stages of Esophageal Malignancies; Surgical Treatment of Esophageal Malignancies; Medical Treatment of Esophageal Malignancies; Endoscopic Diagnosis and Treatment of Earlier Stage of Gastric Malignancies; Surgical Treatment of Gastric Malignancies; Medical Treatment of Gastric Malignancies; Diagnosis and Staging of Pancreatic Malignancies; Surgical Treatment of Pancreatic Malignancies; Managements of Borderline Respectable and Locally Advanced Unresectable Pancreatic Malignancies; Medical Treatment of Advanced Pancreatic Malignancies; Diagnosis and Non-Surgical Treatment of Liver Malignancies; Surgical Treatment of Liver Malignancies and Live Transplantation; Image Guided Therapy of Liver Malignancies; Diagnosis and Medical Treatment of Malignancies of the Biliary Tract; Surgical Treatment of Malignancies of the Biliary Tract; Diagnosis and Medical Treatment of Colorectal Malignancies; Surgical Treatment of Colorectal Malignancies; Multimodality Management of Oligometastatic Colorectal Cancer; Rare Gastrointestinal Malignancies - Stromal Tumor, Neuroendocrine Tumor and Small Bowel Tumor;

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Book SynopsisThis invaluable book provides an introduction to the development and application of molecular biology with a focus on translational research development in a variety of gastrointestinal cancers.Multidisciplinary Management of Gastrointestinal Cancers will emphasize the multidisciplinary aspects of GI cancer diagnosis, treatment and management, introduce the application of new techniques in GI cancer therapy; guide clinicians/experts to use newly developed evidence-based information and knowledge in patient care.This book will also discuss the role of supportive care and quality of life issues in patients with GI malignancies.

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Book SynopsisThis book provides an insightful analysis of the chemopreventive actions of flavonoids. Flavonoids are naturally occurring constituents of plants that have been traditionally used as anti-inflammatory and anti-cancer medicines. In addition, human consumption of vegetables and fruits with high concentrations of flavonoids is associated with decreased cancer mortalities rates.Flavonoids, Inflammation and Cancer presents an in-depth analysis of the mechanisms by which flavonoids are thought to prevent inflammation and the development of GI and steroid-responsive cancers. In addition, the promise and pitfalls associated with using flavonoids as chemopreventive agents are discussed.This book is an invaluable reference for basic and clinical scientists who are interested in exploring the link between nutrition and cancer.Table of ContentsIntroduction and Chemical Structures of Flavonoids; Mechanisms by Which Flavonoids Exert Their Beneficial Effects; Flavonoids and the Inflammatory Response; Flavonoids and Cancers of the GI Tract; Flavonoids and Steroid-Responsive Cancers; Future Challenges Associated with the Medicinal Use of Flavonoids;

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Book SynopsisThis book will serve as the preeminent text book on the topic of 'base excision repair', a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes. The book, which includes contributions from many of the world leaders in the field, provides a detailed description of the molecular mechanisms of base excision repair, as well as its emerging relationship to epigenetic regulation, the aging process and human disease, such as cancer susceptibility, immunological defects and neurological disorders. The book will also cover the state-of-the-art technologies being developed to assess base excision repair capacity among individuals in the population, in addition to the strategies being employed to target base excision repair as part of therapeutic paradigms to eradicate disease, namely cancer.This book represents one of the most extensive efforts to date to cover the topic of 'base excision repair'. It includes chapters by many of the most established investigators in the field, from all over the world.Table of ContentsHistory of Base Excision Repair (BER) and Book Overview (David M Wilson III); Uracil DNA Glycosylases (Hans Krokan); The GO System: OGG1 and MYH (Sheila David); NEIL and NTH1 Glycosylases (Susan Wallace); Alkylative DNA Glycosylase, AAG/MPG (Leona Samson); Abasic Endonuclease, APE1 (Gianluca Tell); DNA Polymerases in BER and Pathway Choice (Samuel Wilson); End-Processing in BER (Michael Weinfeld); PARP/XRCC1 Axis in BER (Janet Hall); DNA Ligases in BER (Alan Tomkinson); Post-Translational Regulation of BER (Robert Sobol); BER in Epigenetic Programming (TDG) (Primo Schar); BER in the Immune Response (SHM, CSR) (Carol Schrader); BER in Disease Etiology (Cancer, Lupus) (Joann Sweasy); BER in TNR Expansion Disorders (Margherita Bignami); BER in Neurological Disease (Yasaku Nakabeppu); Assessing BER Capacity in the Human Population (Zachary Nagel); BER as a Prognostic Marker (Srinivasan Madhusudan); BER as a Therapeutic Target (R Stephen Lloyd); Mitochondrial BER (Nadja de Souza Pinto); BER in Aging (Tinna Stevnsner);

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Book SynopsisThere is something special about cancer compared to other diseases. It is a horrific disease that has defied attempts to find a reliable cure. Life spans after diagnosis have increased, but the mortality rate has remained about the same even after 40 years of extensive research. Cancer provides a major scientific challenge. Tumors evolve and spread in response to internal and external factors that involve feed-back mechanisms and non-linear behavior. In recent years, physicists have become involved in studying cancer, with the ultimate aim of finding a cure. Physicists approach a problem with unique experimental, theoretical, and computational skills and perspectives. This book will be comprised of chapters written by physicists from all over the world who perform research on cancer. They will describe their research and summarize their results.

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Book SynopsisPart 1.  Prevention, Screening& Evaluation: .- 1. Epidemiology of Breast cancer.- 2. ANATOMY OF THE BREAST.- 3. Chemoprevention in breast cancer.- 4. BRCA and other novel mutations: Target Population and Risk Reduction Methods.- 5. Breast cancer screening.- . Part 2.  Breast Cancer Diagnosis, Pathology & Gene Signature: .- 6. Imaging in breast cancer.- 7. Radiology interventions in breast cancer.- 8. Functional imaging in breast cancer: Focus on PET-CT.- 9. Workup and staging for breast cancer.- 10. Pathology & Molecular Classification of Breast Cancer.- 11. Gene Signatures in Management of Breast Cancer.- . Part 3.  Management of early and LABC Breast Cancer: .- 12. Introduction to oncoplastic breast conservation surgery (OPBCS).- 13. Axillary management in breast cancer.- 14. Mastectomy and its relevance in today's era.- 15. Breast reconstruction: evidence and challenges.- 16. Evolution of radiation in early breast cancer.- 17. APBI- Current Status and techniques.- 18. Tailoring of Radiation after NACT.- 19. Regional Nodal Irradiation.- 20. Tailoring Post Mastectomy Radiotherapy .- 21. Target delineation, Radiation planning and evaluation.- 22. Radiation planning and evaluation.- 23. Management of early and LABC Breast Cancer: Chemotherapy and targeted therapy in breast cancer.- 24. PERSONALIZATION OF ENDOCRINE THERAPY IN HORMONE RECEPTOR POSITIVE BREAST CANCER.- 25. Evolving Technological Advances in Management of Early and Locally Advanced Breast Cancers.- . Part 4.  Management of Metastatic Breast Cancer (MBC): .- 26. Role of surgery in metastatic breast cancer and its justification.- 27. Oligometastatic breast cancer.- 28. Systemic Therapy for Hormone positive breast cancer.- 29. Tailoring treatment in Hormone negative carcinoma breast .- . Part 5.  Special Issues Part I: .- 30. High-Risk Lesion of Breast.- 31. Management of inflammatory breast cancer.- 32. Challenges in management of Breast cancer in young women.- 33. BREAST CANCER IN ELDERLY FEMALE.- 34. Pregnancy associated breast cancer.- 35. Management of non IDC histology breast cancer.- . Part 6.  Special Issues Part II .- 36. Management of Non-Palpable Breast Lesion.- 37. Evaluation of Breast Cancer at Recurrence.- 38. Current Evidence In The Management Of Recrrent Breast Cancer.- 39. Skin Sparing Mastectomy.- 40. Triple negative breast cancer: Burden, Biology and Challenges and Management.- . Part 7. Adjuvant treatment for DCIS.- 41. Adjuvant treatment for DCIS.- . Part 8.  Special Issues Part III.- 42. Surveillance in Breast Cancer Survivors.- 43. Supportive and Palliative care in Breast Cancer.- 44. Radiation and Chemotherapy induced Cardiac toxicity in Breast cancer.- 45. Bone Health in Breast Cancer Patients.- 46. Breast cancer: Mental Health and Psychosocial Impact.- 47. Breast Cancer Rehabilitation.- 48. Preoperative radiation in breast cancer.

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Book Synopsis

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