Neurology and clinical neurophysiology Books

Book SynopsisThe brain and the spinal cord, together, compose the central nervous system. Only relatively recently has research shifted focus to consider the integral functions at the individual neuronal and network levels that are mediated by the spinal cord. In this volume, recent work is presented addressing developments in this emerging area. Short reviews examine motor neuron synaptic plasticity, molecular signaling in motor circuits, advances in in vivo and in vitro imaging of spinal cord injury, inhibitory and excitatory locomotor programs, and mapping the circuitry of tactile and sensory functions, including nociception and pain relief. Collectively, these papers provide an overview of some of the most exciting topics in spinal cord research—spanning basic cellular mechanisms to translational approaches. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.Table of ContentsMolecular, genetic, cellular, and network functions in the spinal cord and brainstem 1 Paul S. G. Stein Neurotransmitters and synaptic components in the Merkel cell-neurite complex, a gentle-touch receptor 13 Srdjan Maksimovic, Yoshichika Baba and Ellen A. Lumpkin Principles of interneuron development learned from Renshaw cells and the motoneuron recurrent inhibitory circuit 22 Francisco J. Alvarez, Ana Benito-Gonzalez and Valerie C. Siembab Dorsally derived spinal interneurons in locomotor circuits 32 Anna Vallstedt and Klas Kullander Neuronal correlates of the dominant role of GABAergic transmission in the developing mouse locomotor circuitry 43 Lea Ziskind-Conhaim GluA1 promotes the activity-dependent development of motor circuitry in the developing segmental spinal cord 54 Angela M. Jablonski and Robert G. Kalb Optical imaging of the spontaneous depolarization wave in the mouse embryo: origins and pharmacological nature 60 Yoko Momose-Sato and Katsushige Sato Imaging spinal neuron ensembles active during locomotion with genetically encoded calcium indicators 71 Christopher A. Hinckley and Samuel L. Pfaff Glutamatergic reticulospinal neurons in the mouse: developmental origins, axon projections, and functional connectivity 80 Marie-Claude Perreault and Joel G. Glover Pre- and postsynaptic inhibitory control in the spinal cord dorsal horn 90 Rita Bardoni, Tomonori Takazawa, Chi-Kun Tong, Papiya Choudhury, Gregory Scherrer and Amy B. MacDermott Activity-dependent development of tactile and nociceptive spinal cord circuits 97 Stephanie C. Koch and Maria Fitzgerald Force-sensitive afferents recruited during stance encode sensory depression in the contralateral swinging limb during locomotion 103 Shawn Hochman, Heather Brant Hayes, Iris Speigel and Young-Hui Chang Motor primitives and synergies in the spinal cord and after injury—the current state of play 114 Simon F. Giszter and Corey B. Hart A dual spinal cord lesion paradigm to study spinal locomotor plasticity in the cat 127 Marina Martinez and Serge Rossignol The effects of endocannabinoid signaling on network activity in developing and motor circuits 135 Peter Wenner Hypoxia-induced phrenic long-term facilitation: emergent properties 143 Michael J. Devinney, Adrianne G. Huxtable, Nicole L. Nichols and Gordon S. Mitchell Axon regeneration and exercise-dependent plasticity after spinal cord injury 154 John D. Houle and Marie-Pascale Côté Accelerating locomotor recovery after incomplete spinal injury 164 Brian K. Hillen, James J. Abbas and Ranu Jung

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Book SynopsisThe fifth installment of Addiction Reviews provides refereed reviews on learning theory and addition, deep brain stimulation and addiction, novel therapeutic approaches to addiction, developmental studies of reward, genetics and brain imaging in addiction, genetics of alcoholism and its comorbidities, in addition to other state-of-the art topics in addiction science. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit: http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information on becoming a member.Table of ContentsPreface to Addiction Review iv George R. Uhl Evaluation of reward from pain relief 1 Edita Navratilova, Jennifer Yanhua Xie, Tamara King and Frank Porreca Associative learning mechanisms underpinning the transition from recreational drug use to addiction 12 Lee Hogarth, Bernard W. Balleine, Laura H. Corbit and Simon Killcross Lipids and addiction: how sex steroids, prostaglandins, and cannabinoids interact with drugs of abuse 25 Emma Leishman, Kevin J. Kokesh and Heather B. Bradshaw The genetics of alcohol dependence 39 Marcella Rietschel and Jens Treutlein Substance use disorders: a theory-driven approach to the integration of genetics and neuroimaging 71 Hollis C. Karoly, Nicole Harlaar and Kent E. Hutchinson Analytical strategies for large imaging genetic datasets: experiences from the IMAGEN study 92 Charlotte Nymberg, Tianye Jia, Barbara Ruggeri and Gunter Schumann Addiction and corticotropin-releasing hormone type 1 receptor antagonist medications 107 Carlo Contoreggi, Mary R. Lee and George Chrousos Deep brain stimulation of the nucleus accumbens for the treatment of addiction 119 Ulf J. Müller, Jürgen Voges, Johann Steiner, Imke Galazky, Hans-Jochen Heinze, Michaela Möller, Jared Pisapia, Casey Halpern, Arthur Caplan, Bernhard Bogerts and Jens Kuhn

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Book SynopsisThis is the second of two Annals volume (see also Volume 1262) of papers by speakers at the 8th International Society for Neuroimmodulation Congress held in Dresden, Germany, October 2011. The papers focus on interactions among the immune, endocrine, and nervous systems that occur at multiple levels, from intracellular pathways by immune and neuro-endocrine mediators, to the exchange of information between the three systems that results in physiologic and adaptive effects. In certain instances, however, these interactions may be unbalanced or even disrupted, which can contribute to pathology, and aspects of such pathobiology are presented in some of the contributions. This volume aims focuses on translational science aspects of immune-neuro-endocrine interactions. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632 ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Sciences receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.Table of ContentsThymic atrophy in acute experimental Chagas disease is associated with an imbalance of stress hormones Ailin Lepletier Vinícius de Frias Carvalho Alexandre Morrot Wilson Savino 45 Endocrine, metabolic, and immunologic components of HIV infection Guido Norbiato 51 Neuroimmunomodulation and neuropsychiatric diseases Autoimmune diseases and infections as risk factors for schizophrenia Michael E. Benros Preben B. Mortensen William W. Eaton 56 Antidepressants prevent hierarchy destabilization induced by lipopolysaccharide administration in mice: a neurobiological approach to depression Daniel Wagner Hamada Cohn Denise Kinoshita João Palermo-Neto 67 Peripheral immune system and neuroimmune communication impairment in a mouse model of Alzheimer's disease Lydia Giménez-Llort Ianire Maté Rashed Manassra Carmen Vida Mónica De la Fuente 74 Effects of plasmalogens on systemic lipopolysaccharide-induced glial activation and β-amyloid accumulation in adult mice Toshihiko Katafuchi Masataka Ifuku Shiro Mawatari Mami Noda Kiyotaka Miake Masaaki Sugiyama Takehiko Fujino 85 Biological memory of childhood maltreatment: current knowledge and recommendations for future research Katharina Schury Iris-Tatjana Kolassa 93 Neuroimmunomodulation of pain, and neoplastic diseases Chronic neuropathic pain-like behavior and brain-borne IL-1β Adriana del Rey A. Vania Apkarian Marco Martina Hugo O. Besedovsky 101 Experimental endotoxemia as a model to study neuroimmune mechanisms in human visceral pain Sven Benson Harald Engler Manfred Schedlowski Sigrid Elsenbruch 108 The neuroimmune connection interferes with tissue regeneration and chronic inflammatory disease in the skin Eva M.J. Peters Christiane Liezmann Burghard E. Klapp Johannes Kruse 118 17α-androstenediol-mediated oncophagy of tumor cells by different mechanisms is determined by the target tumor Roger M. Loria Martin R. Graf 127 Cellular and molecular players in the atherosclerotic plaque progression Rita Businaro Angela Tagliani Brigitta Buttari Elisabetta Profumo Flora Ippoliti Claudio Di Cristofano Raffaele Capoano Bruno Salvati Rachele Riganò 134

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Book SynopsisEssays from noted contributors trace the evolution of the neurological patient's role, treatment, and place in the history of medicine. Parkinson's, Alzheimer's, Tourette's, multiple sclerosis, stroke: all are neurological illnesses that create dysfunction, distress, and disability. With their symptoms ranging from impaired movement and paralysis to hallucinationsand dementia, neurological patients present myriad puzzling disorders and medical challenges. Throughout the nineteenth and twentieth centuries countless stories about neurological patients appeared in newspapers, books, medical papers, and films. Often the patients were romanticized; indeed, it was common for physicians to cast neurological patients in a grand performance, allegedly giving audiences access to deep philosophical insights about the meaning of life and being. Beyond these romanticized images, however, the neurological patient was difficult to diagnose. Experiments often approached unethical realms, and treatment created challenges for patients, courts, caregivers, and even for patient advocacy organizations. In this kaleidoscopic study, the contributors illustrate how the neurological patient was constructed in history and came to occupy its role in Western culture. Stephen T. Casper is assistant professor in Humanities and Social Sciences at Clarkson University. L. Stephen Jacyna is reader in the History of Medicine and Director of the Centre for the History of Medicine at University College London.Trade ReviewThis collection adds up to a very welcome and readable widening of standard medical accounts of the history of neurology. Readers, medical and non-medical, can thus turn to the book for information, for appreciation of what historians have and have not done, and for stimulus from the range of contemporary practice in the history of medicine. * BULLETIN OF THE HISTORY OF MEDICINE *This book is very readable, and its chapters achieve a good deal of coherence. The two final parts closely analyze the place of the patient in the evolution of the discipline [of neurology]. Taken together with the Introduction, they form a brilliant frame for the other articles in this collective work. * GESNERUS *An important contribution to the field that promises to elicit further research by these and other scholars committed to exploring what makes the neurological patient so intriguing-not just for medical history, but for the field of history in general. * H-NET *An important and imaginatively organized contribution to the largely unstudied -- but crucial -- history of the interaction between specialization, disease concepts, patient needs, and clinical practice. This book is relevant to any serious student of medical history or the sociology of medicine. -- Charles E. Rosenberg, professor of the history of science, and the Ernest E. Monrad Professor in the social sciences, Harvard UniversityThe Neurological Patient in History is a valuable and welcome addition to the historiography. It not only places the neurological patient firmly in the spotlight, it also encourages readers to re-examine the patient using fresh and thought-provoking lines of enquiry.... This volume will be used as a reference text for years to come. * REVIEWS IN HISTORY *A satisfyingly eclectic account of how patients have been diagnosed and treated and how they have experienced health and illness during the last one hundred and fifty years. There are many fine contributions to this volume. * AMERICAN HISTORICAL REVIEW *Table of ContentsIntroduction The Patient's Pitch: The Neurologist, the Tuning Fork, and Textbook Knowledge Neurological Patients as Experimental Subjects: Epilepsy Studies in the United States Speaking for Yourself: The Medico-Legal Aspects of Aphasia in Nineteenth-Century Britain The Spouse, the Neurological Patient, and Doctors Disappearing in Plain Sight: Public Roles of People with Dementia in the Meaning and Politics of Alzheimer's Disease The Cursing Patient: Neuropsychiatry Confronts Tourette's Syndrome, 1825-2008 The Psychasthenic Poet: Robert Nichols and His Neurologists The Encephalitis Lethargica Patient as a Window on the Soul Neuropatients in Historyland The Neurological Patient in History: A Commentary Bibliography List of Contributors Index

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Book SynopsisWorld-renowned experts debate key topics in pediatric neurosurgery In Controversies in Pediatric Neurosurgery, leading clinicians from around the globe present concrete advice and frank commentary on alternative options for the treatment and management of specific cranial and spinal disorders. Each succinct, easily accessible chapter addresses a different condition in a point/counterpoint format that discusses the pros and cons of the various treatment options, including surgical approaches and techniques. This highly practical, balanced coverage equips readers to make well-informed choices when selecting the most appropriate treatment modality for a particular diagnosis. Features: Lessons Learned at the end of each chapter, in which the authors summarize the debate with multiple viewpoints and carefully considered recommendations based on published evidence and their own clinical experience Incisive dialogue on twenty hot topics in the field, including how to manage arachnoid cysts, craniosynostosis, tethered cord, hydrocephalus, chiari malformations, epilepsy, aneurysms, and more Clinical and personal insights from international contributors on the variability of surgical training, experience, and available resources in different parts of the world Guidance on how to discuss treatment options and strategies to patients and their families This book is essential reading for every clinician, resident, or fellow who needs a firm understanding of the most controversial issues in pediatric neurosurgery to be able to make the best decision for the appropriate treatment option for patients in their care. Trade ReviewUseful as a measure of alternatives are currently available...excellent ilustrations.--Doody's Review I would certainly recommend this book as a good addition to a general neurosurgeons library or to the department library in most neurosurgical departments. Journal of NeurosurgeryTable of ContentsI Intracranial 1 Arachnoid Cyst 2 Communicating Hydrocephalus 3 Noncommunicating Hydrocephalus 4 Compartmentalized Hydrocephalus 5 Slit Ventricle Syndrome 6 Craniopharyngioma 7 Optic Pathway/Hypothalamic Gliomas 8 Ependymomas 9 Scaphocephaly/Sagittal Synostosis 10 Deformational Plagiocephaly 11 Intracranial Suppuration 12 Chiari Malformations 13 Intractable Epilepsy 14 Moyamoya Disease 15 Pediatric Aneurysms II Intraspinal 16 Myelomeningocele 17 Lipomyelomeningocele/Tethered Cord 18 Intramedullary Spinal Cord Tumors 19 Spasticity 20 Syringomyelia

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Book SynopsisTumors of the Pediatric Central Nervous System, Second Edition, provides readers with both medical management and surgical perspectives on the clinical, pathological, and radiological diagnoses and treatment of pediatric CNS tumors. It includes complete coverage of the latest diagnostic and management techniques, state-of-the-art technologies, and trends in the surgical treatment of pediatric tumors. Highlights of the Second Edition: Contains 19 new chapters on such topics as recent advances in the cytogenetics and molecular biology of pediatric brain tumors, gangliogliomas and miscellaneous spinal cord tumors in children, post-chemotherapy morbidity, and many more Addresses the important issues of long-term chronic treatment of pediatric tumor patients and related outcome measures Includes summary boxes and tables that distill large amounts of information for quick review Written by editors and contributors who are world-renowned experts in the field of pediatric neurosurgery and oncology Neurosurgeons, neurologists, oncologists, radiation oncologists, and pediatricians caring for patients with tumors of the central nervous system will find this book to be an essential resource that they will repeatedly consult as they strive to enhance patient care.

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Book SynopsisAuthored by renowned neuro-radiologist Steven P. Meyers, Differential Diagnosis in Neuroimaging: Brain and Meninges is a stellar guide for identifying and diagnosing brain pathologies based on location and neuroimaging results. The succinct text reflects more than 25 years of hands-on experience gleaned from advanced training and educating residents and fellows in radiology, neurosurgery, and neurology. The high-quality MRI, CT, PET, PET/CT, conventional angiography, and X-ray images have been collected over Dr. Meyers's lengthy career, presenting an unsurpassed visual learning tool. The distinctive 'three-column table plus images' format is easy to incorporate into clinical practice, setting this book apart from larger, disease-oriented radiologic tomes. The layout enables readers to quickly recognize and compare abnormalities based on high-resolution images. Key Highlights Tabular columns organized by anatomical abnormality include brain imaging findings and a summary of key clinical data that correlates to the images Comprehensive imaging of the brain, ventricles, meninges, and neurovascular system in both children and adults, including congenital/developmental anomalies and acquired disease More than 1,900 figures illustrate the radiological appearance of intracranial lesions, masses, neurodegenerative disorders, ischemia and infarction, and more This visually rich resource is a must-have diagnostic tool for radiologists, neurosurgeons, and neurologists, and residents and fellows. The highly practical format makes it ideal for daily rounds, as well as a robust study guide for physicians preparing for board exams.Trade ReviewThis is a highly valuable book that contains a tremendous amount of information in words and pictures. It should be a must-have guide and reference manual for anyone involved in neurology and neurosurgery. -- BIZ INDIA ...an outstanding way to learn imaging anatomy and corresponding diseases...This [series] is a highly desirable set of books and would be a valuable addition to any neuroradiologist's personal collection, and certainly to any departmental or sectional library. -- AJNR BlogTable of Contents1 Brain (Intra-Axial Lesions) 2 Ventricles and Cisterns 3 Extra-Axial Lesions 4 Meninges 5 Vascular Abnormalities

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Book SynopsisMaster spine surgeons Alexander R. Vaccaro, Richard G. Fessler, and a cadre of esteemed co-editors have compiled the most comprehensive textbook to date detailing minimally invasive spine (MIS) versus open spine surgery techniques. Controversies in Spine Surgery, MIS versus OPEN: Best Evidence Recommendations features debates by renowned experts on one of the most provocative topics in spine surgery. Twenty-four chapters systematically organized into four sections — degenerative, trauma, tumor, and other issues, cover procedures and underlying pathologies, backed by a large, diverse body of literature. MIS and open approaches are thoroughly compared and contrasted in each chapter. Evidence is presented and analyzed in an objective manner with 'opposing sides' presenting differing opinions and techniques, resulting in a synchronous collection of pros and cons. Every chapter is masterfully summed up by the book's editors — each of whom have varying stances on the topics at hand. This unique 'duel' and 'duet' discussion enables readers to assimilate information, benefit from the balanced harmony between divergent opinions, and reach their own conclusions. Key Highlights Comparative risks, benefits, complications, and outcomes for a full spectrum of lumbar, thoracic and cervical procedures MIS versus open approaches for lumbar stenosis, synovial cysts, lumbar adjacent segment degeneration, degenerative scoliosis, flatback syndrome, thoracic disc herniation, and dural tears Tumor resection and stabilization, quality of life issues, and potential advantages and risks of MIS techniques Key differences in MIS versus open operations such as radiation exposure and costs Analysis of 3-D navigational imaging to improve outcomes and reduce radiation exposure and operating time This book is a tremendous, evidence-based tool to guide spine surgeons as they make important decisions on selecting the most optimal spine surgery techniques. It is a must-have resource for all resident and veteran orthopaedic surgeons and neurosurgeons who specialize in treating patients with spine conditions.Table of ContentsPart I: Degenerative 1 Lumbar Discectomy: Is Tubular or Endoscopic Discectomy Better Than Traditional Microdiscectomies? 2 Is Lumbar Stenosis Best Treated with an Open Laminectomy? 3 Facet Cysts: Is There an Advantage to Treating Synovial Cysts with Minimally Invasive Techniques? 4 Transforaminal Lumbar Interbody Fusion: Minimally Invasive versus Open 5 The Lateral Transpsoas Approach versus ALIF: Do the Risks of Lateral Interbody Fusion Outweigh the Benefits Compared to Anterior Lumbar Interbody Fusion? 6 Is AxiaLIF Comparable to Open Fusion with ALIF and Posterolateral 360° Fusion at L5–S1? 7 Multiple-Level Interbody Fusion: How Do Two-Level Fusion Techniques Compare between Open and Minimally Invasive Surgery? 8 Is Lumbar Adjacent Segment Degeneration Best Treated Using Minimally Invasive Surgery over Open Fusion Techniques? 9 Degenerative Scoliosis: Is There an Advantage to Using Minimally Invasive Techniques to Treat Degenerative Scoliosis? 10 Flatback Syndrome: Can Lumbar Flatback Syndrome Be Treated Adequately with Minimally Invasive Techniques? 11 Can Thoracic Disc Herniation Be Effectively Treated Using Minimally Invasive Techniques? 12 Posterior Cervical Foraminotomy 13 Complications of Instrumentation: Is There a Higher Complication Rate in Placing Instrumentation via a Minimally Invasive Technique Compared with an Open Technique? 14 Dural Tears: Should a Minimally Invasive Complication Such as a Dural Tear Routinely Be Opened for Adequate Repair or Are There Safe and Reliable Minimally Invasive Techniques for Dural Closure? 15 Do Minimally Invasive Techniques Broaden the Scope for Geriatric Spine Surgery? Part II: Trauma 16 Thoracolumbar Burst Fractures: Can Thoracolumbar Burst Fractures Be Effectively Managed Using Minimally Invasive Surgery Techniques? 17 Open and Minimally Invasive Treatment of Cervical Spine Fractures Part III: Tumor 18 Thoracolumbar Metastatic Tumors: Comparison of Minimally Invasive Surgery versus Open Techniques for Addressing Thoracolumbar Metastatic Tumor Resection and Stabilization 19 Intradural Spine Tumors: Is There an Advantage to Removing Intradural Spine Tumors Using an MIS Approach? 20 Quality of Life in Advanced Tumors: Can Minimally Invasive Surgery Techniques Improve the Quality of Life of Patients with Advanced Oncologic Disease to Allow for Decreased Pain or Should Traditional Techniques of Palliation Be Used? Part IV: Other Issues 21 Radiation Exposure: How Does Radiation Exposure Differ between Open and Minimally Invasive Techniques? 22 Infection Rates: How Do Infection Rates Compare between MIS and Open Spine Techniques? 23 Cost: Which Costs More, Open or Minimally Invasive Surgery? 24 Success Rates and Time: Can Three-Dimensional Navigational Imaging Improve the Success and Time Required for Minimally Invasive Surgery and Minimize Radiation Exposure to Those in the OR Suite?

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Book SynopsisMasterful 2D and 3D head, neck, and brain dissections provide unsurpassed insights into head, neck, and brain anatomy An internationally renowned and beloved author, educator, brain anatomist, and neurosurgeon, Professor Albert Rhoton has a special place in medical history. He was revered by students and colleagues and is regarded as one of the fathers of modern microscopic neurosurgery. A driving principle in his anatomy lab was the simple phrase, "Every Second." This was embraced in his philosophy that every second of every day, a patient's life was improved by a surgeon assisted by the anatomic knowledge his lab helped elucidate and distribute. Rhoton's Atlas of Head, Neck, and Brain is the visually exquisite crowning achievement of Dr. Rhoton's brilliant career and unwavering dedication to the intertwined pursuits of surgical anatomy and neurosurgery. The atlas reflects the unparalleled contributions Dr. Rhoton made to the contemporary understanding of neurosurgical anatomy. Dr. Peris-Celda, with the collaboration of an impressive cadre of international multidisciplinary experts, worked closely under Dr. Rhoton's tutelage on this project. This book is the culmination of 5 years of work and experience gleaned from more than 40 years of surgical anatomy research and exquisite dissection techniques performed in Dr. Rhoton's laboratory. Special Features Each anatomic dissection meticulously labeled with English and Latin descriptors for easy cross referencing with other resources. Multiple views of the most complex regions of the head, neck, and brain provide a deeper understanding of anatomy. More than 600 anatomical images systematically organized in four major sections: Osteology of the Head and Neck; Face and Neck; Ear, Nose, Pharynx, Larynx, and Orbit; and Neuroanatomy and Cranial Base. Superb 2D images presented in a large printed format to optimize the viewing experience. 3D digital images fully realize the beauty of the dissections and enhance the learning process. Specimens injected with colored silicone provide better visualization of arteries and veins. Breathtakingly stunning, this atlas is certain to be a treasured reference for medical students, residents, and clinicians specializing in neurosurgery, facial plastic surgery, otolaryngology, maxillofacial surgery, and craniofacial surgery for many years to come.Table of ContentsPart I Osteology of the Head and Neck 1 Adult and Fetal Skull 2 Bones of the Skull and Skull Bone Articulations 3 Cervical Vertebrae Part II Face and Neck 4 Face: Superficial Dissection 5 Face: Deep Dissection 6 Anterior Aspect of the Neck: Deep Dissection 7 Anterior Aspect of the Neck: Deep Dissection 8 Posterior Aspect of the Neck 9 Parapharyngeal Dissection Part III Ear, Nose, Pharynx, Larynx, and Orbit 10 External and Middle Ear 11 Internal Ear 12 Nose: Sagittal Dissection 13 Nose: Coronal Dissection 14 Endonasal Endoscopy 15 Pharynx 16 Larynx 17 Orbit 18 Eye and Orbital Contents 19 Internal Structure of the Eyeball Part IV Neuroanatomy and Cranial Base 20 Cerebrum 21 Cerebellum and Brainstem 22 Brain, Meninges, and Sutures 23 Cerebrovascular and Intraventricular Dissection 24 Cranial Base and Craniocervical Junction 25 Sagittal and Endoscopic Dissection of the Cranial Base 26 Cranial Nerves 27 Brain Sections 28 Fiber Dissection of the Brain

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Book SynopsisTourette syndrome is a disorder of the nervous system that involves involuntary vocal and motor tics - sudden, rapid, repeated sounds and movements. Tourette is usually first identified in children between the ages of 7 and 10, and boys are four times as likely as girls to have the disorder. The disorder can be mild or severe, with about 10 percent of Americans having a mild form, according to the National Institutes of Health. ""Tourette Syndrome"" explores the signs, symptoms, causes, and treatment of this bizarre and misunderstood neurological condition, which is often referred to as a 'tic' disorder. Following an overview of Tourette syndrome, the book details its history, symptoms, biological causes and triggers of tic episodes, epidemiology, and current forms of treatment. Ways in which parents and children cope with Tourette syndrome and its social stigma, as well as psychiatric conditions that are commonly associated with it, are also discussed. Chapters of this book include: Tourette Syndrome - An Overview; Signs and Symptoms of Tourette Syndrome; Demographics of Tourette Syndrome; Causes of Tourette Syndrome; Medical Treatments; Psychosocial and Behavioral Therapy for Tourette Syndrome; Psychiatric Disorders Commonly Associated with Tourette Syndrome; and, Coping Strategies for Tourette Syndrome Patients.

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Book SynopsisNow more than ever, sufferers of opioid use disorder (OUD) need an authoritative guide. Brimming with expert advice and actionable tips from noted addiction psychiatrist Dr. Adam Bisaga, Overcoming Opioid Addiction demystifies addiction and destigmatises medication-assisted treatment. In this book, OUD sufferers, their loved ones, and professionals alike will learn everything they need to know, including: • The science that underlies addiction and why the opioid epidemic has taken hold and become so deadly • The different stages and effective methods of treatment, including detoxification vs. maintenance medications, as well as behavioural therapy • How to deal with relapses and how to thrive despite OUD. Complete with a brief guide tailored to families that offers crucial, life-saving information, such as how to select the best program, manage medications, and reverse an overdose, this is the ultimate guide to identifying, treating, and overcoming OUD - once and for all.

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Book SynopsisAn updated guide to diagnosing peripheral nerve injuries Examination of Peripheral Nerve Injuries, Second Edition, is an updated version of an anatomically based guide that teaches neurosurgeons how to properly examine a patient with a suspected focal neuropathy. This new edition contains unique, full-color illustrations that, along with high-quality photographs, help readers master the details of performing specific procedures and examinations on patients with peripheral nerve injuries.Key Features: More than 80 new full-color illustrations guide the reader through each technique Photographs illustrate muscular examination techniques Anatomical relationships are emphasized throughout the book Focuses on the most common anatomical variations, using both schematic figures and simplified text descriptions to facilitate learning Neurosurgeons and neurologists, as well as residents in these specialties, will read this book cover to cover and refer to it whenever they are preparing to examine patients with complex peripheral nerve injuries.Table of Contents1 Median Nerve 2 Ulnar Nerve 3 Radial Nerve 4 Brachial Plexus Anatomy 5 Clinical Evaluation of the Brachial Plexus 6 Sciatic Nerve 7 Inguinal Complex of Nerves 8 Lumbosacral Plexus

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Book SynopsisEssential neuroradiology cases and board-type Q&A review to help you pass your exam! Neuro Imaging Second Edition from Roy Riascos, Eliana Bonfante, and Susana Calle features 100 new cases along with two board-type multiple choice questions for each. This latest edition features state-of-the-art imaging technologies including perfusion techniques, spectroscopy, nuclear medicine, and 3D reconstructions. Updated and new classification systems have been integrated into brain tumor, traumatic spine injury, and intracranial aneurysm cases. For maximum ease of self-assessment, each case begins with the clinical presentation on the right-hand page; study that and then turn the page for imaging findings, differential diagnoses with the definitive diagnosis, essential facts, pearls and pitfalls, and more. Key Features New to this edition, a question-and-answer section for each case reinforces key concepts Easy-to-read bulleted formatting and concise, point-by-point presentation of the Essential Facts enables learning and retention of high-yield facts and skill-building in neuroradiologic diagnosis Online access to additional cases enables residents to arrange study sessions, quickly extract and master information, and prepare for specialized neuroradiology conferences Thieme's RadCases means cases selected to simulate what you will see on your exams, rounds, and rotations. RadCases helps you to identify the correct differential diagnosis for each case, including the most critical. The series comprehensively covers the following specialties: Breast Imaging · Cardiac Imaging · Emergency Imaging · Gastrointestinal Imaging · Genitourinary Imaging · Head and Neck Imaging · Interventional Radiology · Musculoskeletal Radiology · Neuro Imaging · Nuclear Medicine · Pediatric Imaging · Thoracic Imaging · Ultrasound Imaging This RadCases book comes with a code providing access to additional online cases: 100 in this book plus 250+ more cases and interactive Q&A. Master your cases, pass your exams, and diagnose with confidence: RadCases! This print book includes complimentary access to a digital copy on https://medone.thieme.com. Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.Table of Contents100 Radiology Cases

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Book SynopsisNeurotrauma and Critical Care of the Brain, 2nd edition by renowned neurosurgeons Jack Jallo and Christopher Loftus incorporates salient components of the highly praised first edition. The updated text reflects cutting-edge discussion on traumatic brain injury management in a neurocritical care setting. Contributions from top experts in neurosurgery, neurology, critical care, cardiac and pulmonary care, and trauma surgery provide a concise review of a complex and evolving field. The book lays a solid foundation with discussion of TBI classification, pathophysiology, key blood biomarkers, noninvasive neuromonitoring in severe TBI patients, multimodality monitoring in neurocritical care, and brain imaging modalities. From the prehospital setting to intensive care, top experts share clinical pearls and core guidelines on the management of mild, moderate, and severe TBI and complications. Chapters new to this edition include concomitant injuries, orbital/facial fractures, vascular injuries, spine fractures, autonomic dysfunction, and temperature management. Key Highlights Specialized topics include wartime penetrating injuries, cardiovascular complications of TBI, venous thromboembolism prophylaxis, ethical considerations, TBI costs in the U.S. and the financial return on helmets Management of pediatric brain injuries in the NICU with illustrative cases Nearly 200 high quality illustrations facilitate understanding of complex anatomy and techniques Summary tables provide a handy overview of injury type, causes, characteristics, and recommended imaging modalities This remarkable resource is essential reading for neurosurgeons, neurologists, trauma physicians, critical care and rehabilitation medicine specialists, and residents in these specialties. Paired with Neurotrauma and Critical Care of the Spine, 2nd edition, this dynamic duo is the most up-to-date neurocritical care reference available today.Table of ContentsPart I: Introduction 1. Brain Trauma and Critical Care: A Brief History 2. The Epidemiology of Traumatic Brain Injury in the United States and The World 3. The Classification of Traumatic Brain Injury Part II: Science 4. Pathophysiology of Traumatic Brain Injury 5. Blood Biomarkers: What is Needed in the Traumatic Brain Injury Field 6. Noninvasive Neuromonitoring in Severe Traumatic Brain Injury 7. Multimodality Monitoring in Neurocritical Care 8. Brain Injury Imaging Part III: Management 9. Prehospital Care for Patients with Traumatic Brain Injury 10. Assessment of Acute Loss of Consciousness 11. Guidelines Application for Traumatic Brain Injury 12. Mild Brain Injury 13. Moderate Traumatic Brain Injury 14. Severe Traumatic Brain Injury 15. Wartime Penetrating Injuries 16. Guidelines for the Surgical Management of Traumatic Brain Injury 17. Concomitant Injuries in the Brain-injured Patient 18. Pediatric Brian Injury Part IV: Critical Care 19. Neurological Critical Care 20. Fluids Resuscitation and Traumatic Brain Injury 21. Sedation and Analgesia in Traumatic Brain Injury 22. Mechanial Ventilation and Pulmonary Critical Care 23. Nutrition Support in Brain Injury 24. Cardiovascular Complications of Traumatic Brain Injury 25. Paroxysmal Sympathetic Hyperactivity 26. Venous Thromboembolism Prophylaxis in the Neurocritical Care Population 27. Traumatic Brain Injury and Infection 28. Targeted Temperature Management in Acute Traumatic Brain Injury Part V: Outcome 29. Neurorehabilitation after Brain Injury 30. Prognosis for Traumatic Brain Injury Part VI: Socioeconomics 31. Ethics: Life and Death Choices for Traumatic Brain Injury 32. Cost of Traumatic Brain Injuries in the United States and Return on Helmet Investments

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Book SynopsisThe quintessential reference for bedside medical management of neurocritical care patients Medical management of patients in the neurocritical care unit (NCCU) often spells the difference between life or death and return to normal function or a lifetime disability. As such, it is vital that patients with life-threatening neurological and neurosurgical illnesses receive prompt diagnosis and rapid interventions in the NCCU. The Jefferson Manual for Neurocritical Care by renowned neurosurgeon Jack I. Jallo, neurointensive care physician Jacqueline S. Urtecho, and distinguished colleagues is a high-yield pocket resource ideal for the bedside care of patients with serious, life-altering diseases. Nineteen concise chapters encompass cerebrovascular, neuromuscular, oncologic, and traumatic conditions, as well as core clinical topics applicable to the care of neurocritical patients. Key Highlights Evidence-based management strategies created at Thomas Jefferson University's Vickie and Jack Farber Institute for Neuroscience presented in reader-friendly algorithms, pictures, and charts General chapters cover brain death, sodium dysregulation, nutrition, sedation, pain management, neuromonitoring, and ventilation strategies Disease-specific chapters featuring succinct, bulleted format include epidemiology, causes, diagnostic tests, treatment options, symptoms, common clinical presentation, risk factors, differential diagnoses, and more This manual is an indispensable resource for neurocritical care residents and fellows, NCCU nurses, nurse practitioners, physician assistants, general intensive care physicians, and neurointensivists. This book includes complimentary access to a digital copy on https://medone.thieme.com.Table of Contents1. Encephalopathy and Delirium 2. Cerebrovascular Emergency: Acute Stroke Diagnosis and Management 3. Cerebrovascular Emergency: Spontaneous Intracerebral Hemorrhage (ICH) 4. Cerebrovascular Emergencies: Aneurysmal Subarachnoid Hemorrhage (SAH) 5. Transfusion Medicine and Anticoagulation 6. Cerebral Edema and Elevated Intracranial Pressure 7. Fevers and Infections in the Neuro-ICU 8. Treatment of Status Epilepticus in Adults 9. Trauma 10. Neuromuscular and Other Neurologic Emergencies 11. Brain Tumor Postoperative Management 12. Brain Death in Adults 13. Sodium Dysregulation 14. Nutrition 15. Sedation 16. Pain Management in the Neuro-Intensive Care Unit (ICU) 17. Advanced Hemodynamic and Neurological Monitoring in the Neuro-ICU 18. Neuroimaging 19. Ventilation Strategies in Neuro-ICU

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Book SynopsisEnsure readiness for the USMLE® or any other high-stakes exam covering neuroscience! Thieme Test Prep for the USMLE®: Medical Neuroscience by Manas Das and Lee Baugh fills a void in available board prep materials with its focus on neuroscience. Readers will learn to recall, analyze, integrate, and apply biochemical and molecular biological knowledge to solve clinical problems. Key Highlights Approximately 520 USMLE®-style multiple choice questions on neuroscience, classified as easy, moderate, and difficult, with detailed explanations Questions cover clinical neurology as well as basics of neuroscience such as development, structure, and function Chapters are organized based on neuroanatomical structure and systems, from the spinal cord to the automatic nervous system Neuroimaging section and final exam chapter are invaluable tools for students to utilize before the boards Questions begin with a clinical vignette, and approximately 35% are image-based, mirroring the USMLE® format This essential resource will help you assess your knowledge and fully prepare for the USMLE® Step 1 or COMLEX Level 1 exam. Be prepared for your board exam with the Thieme Test Prep for the USMLE® series! Das: Histology and Embryology Q&A Fontes and McCarthy: Medical Biochemistry Hankin et al: Clinical Anatomy Q&A Harriott et al: Medical Microbiology and Immunology Q&A Kemp and Brown: Pathology Q&A Waite and Sheakley: Medical Physiology Q&A Visit www.thieme.com/testprep to learn more about our online board review question bank.Table of Contents1 Gross Anatomy and the Nervous System 2 Meninges and CSF 3 Blood Supply of the Nervous System 4 Development of the Nervous System 5 Histology of the Nervous System 6 Spinal Cord 7 Medulla 8 Pons 9 Midbrain 10 Cranial Nerves 11 Ascending and Descending Tracts 12 Thalamus 13 Hypothalamus 14 Cerebral Cortex 15 Basal Ganglia 16 Cerebellum 17 Limbic System 18 Auditory System 19 Vestibular System 20 Visual System and Eye Movements 21 Olfactory and Gustatory Systems 22 Autonomic Nervous System 23 Neuroimaging 24 Comprehensive Review

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Book SynopsisFunctional neurosurgery resource features state-of-the-art approaches from renowned experts! For patients with inadequately treated epilepsy, tremor, dystonia, spasticity, depression, obsessive-compulsive disorder, Parkinson's and Alzheimer's disease, functional neurosurgery offers hope. Functional Neurosurgery: The Essentials is a reader-friendly introduction to this fascinating and rapidly evolving field. The text is edited by internationally prominent functional neurosurgeons Jeffrey A. Brown, Julie G. Pilitsis, and Michael Schulder. It features contributions from authors with expertise spanning the disciplines of neurosurgery, neurology, rehabilitation and physical medicine, neurophysiology, bioengineering, psychiatry and ophthalmology. Opening with a brief history of stereotaxy/functional neurosurgery and brain stereotactic frames, 41 concise and coherent chapters explore cutting-edge approaches to a broad range of functionally treatable conditions. The chapters yield a solid foundation of understanding of the field, with insightful commentary, pearls, and nuances from the editors. The starting question in the neuroprosthetics chapter, "Can a computer infer human intention or perception?" brings to life the exciting, inquisitive, and pioneering spirit of this subspecialty. The robust reference list provides a guide to deeper study that should continue throughout training and practice. Highlights Imaging: MRI and CT for stereotactic neurosurgery, fMRI and resting state MRI Movement disorders: A comparative analysis of the risks and benefits of deep brain stimulation versus lesioning Epilepsy: Temporal lobectomy and extra-temporal surgery; invasive monitoring, neuromodulation, laser interstitial thermal therapy, and vagus nerve stimulation Dystonia: Etiology to diagnosis, medical and surgical options Future innovations: Exoskeletons, intention controlled, and visual neuroprosthetics The text is a fundamental resource for neurosurgical residents during their functional neurosurgery rotations and for general neurosurgeons and functional subspecialists on procedures they may not routinely perform in clinical practice. This book includes complimentary access to a digital copy on https://medone.thieme.com.Table of Contents1 History of Innovation in Stereotaxy/Functional Neurosurgery 2 A Brief History of Brain Stereotactic Frames 3 Frameless Navigation 4 MRI and CT Imaging with Stereotactic Neurosurgery 5 Functional Neuroimaging II: fMRI and Resting State MRI 6 Functional Neuroimging II 7 Intraoperative CT Imaging 8 Microelectrode Recordings in Deep Brain Stimulation Surgery for Movement Disorders 9 Cortical and Subcortical Mapping 10 Parkinson Disease–Evaluation and Medical Treatment 11 Surgery for Parkinson's Disease 12 Essential Tremor: Evaluation, Imaging and Medical Treatment 13 Surgery for Essential Tremor 14 Dystonia: Evaluation, Imaging and Medical Treatment 15 Surgical Treatment of Dystonia 16 Deep Brain Stimulation for Rare Movement Disorders 17 Lesioning versus Deep Brain Stimulation for Movement Disorders 18 Spasticity: Evaluation, Medical and Preoperative Considerations 19 Surgery for Spasticity: Rhizotomy and Intrathecal Therapy 20 Epilepsy: Preoperative Evaluation, EEG and Imaging 21 Epilepsy: Temporal Lobectomy with Invasive Monitoring 22 Epilepsy: Extra-Temporal Surgery with Invasive Monitoring 23 Neuromodulation in Epilepsy 24 Laser Interstitial Thermal Therapy for Epilepsy 25 Vagus Nerve Stimulation for Epilepsy 26 Neuroethics Essentials in Functional Neurosurgery for Neurobehavioral Disorders 27 Depression 28 Functional Neurosurgery for Obsessive-Compulsive Disorder 29 Neurosurgery Treatment for Anorexia Nervosa 30 Anterior Capsulotomy for Treatment of Refractory Schizophrenia 31 Alzheimer's Disease: Epidemiology, Pathophysiology and Surgery 32 Normal Pressure Hydrocephalus 33 Principles of Chronic Nociceptive and Neuropathic Pain 34 Neuromodulation for Neuropathic Pain 35 Spinal Cord Stimulation Using High Frequency and Burst Waveform Variation 36 Ablative Procedures for Trigeminal Neuralgia 37 Principles of Trigeminal Neuralgia 38 Intraoperative Neurophysiologic Monitoring during Microvascular Decompression for Trigeminal Neuralgia 39 Neuroprosthetics 40 Exoskeletons 41 Visual Prostheses

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Book SynopsisThis book explores a study of how and under what circumstances children's ideas about the body change over the period of two school years, Primary 1 and 2 (6 and 7 years old), in a ""normal"" classroom setting in an Icelandic primary school. The focus is on children's ideas about the structure, location and function of bones and other organs and how changes in pupils' ideas are affected by the curriculum, teaching methods, teaching materials and teacher/pupil and peer interactions. Special attention is given to the differences between quiet children and more open children in respect to these issues. Result from the study shows that the children were generally more aware of the structures, locations and functions of the various organs than they were of processes and how the organs were interrelated and they were also more aware of the digestive system than other organ systems.

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Book SynopsisThis book explores a study of how and under what circumstances children's ideas about the body change over the period of two school years, Primary 1 and 2 (6 and 7 years old), in a ""normal"" classroom setting in an Icelandic primary school. The focus is on children's ideas about the structure, location and function of bones and other organs and how changes in pupils' ideas are affected by the curriculum, teaching methods, teaching materials and teacher/pupil and peer interactions. Special attention is given to the differences between quiet children and more open children in respect to these issues. Result from the study shows that the children were generally more aware of the structures, locations and functions of the various organs than they were of processes and how the organs were interrelated and they were also more aware of the digestive system than other organ systems.

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Book SynopsisToward the end of World War II, Hitler's many health complications became even more pronounced, making an evil man yet more erratic and dangerous. While the subject of Hitler's health has been catalogued previously, never has it been done so this thoroughly or with this level of up-to-date medical expertise.Tom Hutton's new neurobehavioral analysis of Adolf Hitler draws from a lifetime of medical research and clinical experience to understand how the dictator's particular medical history further warped a deformed personality and altered Hitler's decision making.Dr. Hutton trained under the world-renowned neuropsychologist and father of modern neuropsychological assessment, Dr. Alexander Luria, giving him a uniquely qualified eye to undertake this most difficult assessment.While many books on the subject thumb through the annals of popular psychology to understand history's most famous monsters, Dr. Hutton's latest book uses contemporary clinical knowledge, lucidly synthesizing medical complexities for all audiences.Here Dr. Hutton undertakes a thorough medical history to elucidate a pivotal historical moment, examining how disease impacted Hitler's destructive life.

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Book SynopsisThe quintessential case-based review to prep for and master ABR exams The American Board of Radiology Core, Certifying, and Neuroradiology Subspecialty Exams test an individual's knowledge and understanding of anatomy, pathophysiology, and physics concepts important in diagnostic imaging. For many residents, fellows, and practicing radiologists, preparation for these exams involves several months to years of reading text, interpreting images, and answering countless questions. Neuroradiology Q&A for the Radiology Boards, edited by neuroradiologist Michael Iv, features contributions from other academic neuroradiologists at Stanford University who are passionate about education and paying it forward. The primary goals of this book are to help current and future generations of radiologists ace the neuroradiology section of these exams and improve their clinical skills. The reader-friendly compilation of cases, questions, and answers reflects the invaluable insights of neuroradiologists who recently experienced the arduous journey of studying and sitting for the ABR exams. The book consists of a collection of 100 "standard difficulty" and "challenging" cases organized by the categories of brain, spine, and head and neck. A total 70 cases covering a wide range of brain conditions and diseases include 20 challenging cases. Spine and head and neck pathologies are represented by 15 cases each, both of which include 5 challenging cases. All of the cases illustrate specific pathologies and teaching points likely to be encountered on the exams and in the reading room. Key Features Cases encompass every area of neuroradiology and cover the full age spectrum Consistently formatted cases feature two or three high-yield images, followed by three multiple choice questions that assess comprehension of imaging diagnosis, histopathology, and management Detailed explanations for correct and incorrect answers enhance understanding and acquisition of knowledge This must-have study guide will help radiologists prepare for and ace the Core, Certifying, and/or Neuroradiology Subspecialty ABR exams and improve their clinical knowledge, which ultimately leads to improved patient care. This print book includes complimentary access to a digital copy on https://medone.thieme.com.Table of ContentsBrain Cases 1-50 Cases 51-70 (Challenge) Spine Cases 71-80 Cases 81-85 (Challenge) Head and Neck Cases 86-95 Cases 96-100 (Challenge) List of Cases

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Book SynopsisAttention deficit hyperactivity disorder, or ADHD, is one of the most common developmental disorders, with an average of 9 per cent of children between the ages of five and seventeen diagnosed per year in the USA. It is also one of the most controversial. Since the 1950s, when hyperactivity in children was first diagnosed, psychiatrists, educators, parents and politicians have debated the causes, treatment and implications of the disorder. Hyperactive: The Controversial History of ADHD is the first history of the disorder. Matthew Smith highlights the limitations of regarding ADHD as simply neurological, and contends that hyperactive children are also a product of their social, cultural, political and educational environment. Instead of simply accepting conventional understandings of ADHD, this book addresses the questions central to the emergence of the disorder: Why were children first diagnosed with the disorder? Why did biological explanations become predominant? Why did powerful drugs become the preferred treatment? And why have alternative explanations failed to achieve legitimacy?By thinking through these issues Smith demonstrates how knowledge of the disorder's history can be used to empower those affected to make better choices about diagnosis and treatment. As a historian with past experience of working with troubled children and youth, Matthew Smith offers a history that is not only rigorous, but also accessible and highly relevant to those working with and caring for those diagnosed with ADHD. A revealing and clear-headed study of a controversial and emotive subject, this is an essential book for psychologists, teachers, policy makers and, above all, parents.Trade Review'Matthew Smith persuasively demonstrates the historical contingency of our ideas about hyperactivity. Well written, complex yet sharply argued, this book is a sorely needed corrective to today's therapeutic "common sense" and the ocean of pharmaceuticals it sanctions.' - -- David Herzberg, Associate Professor author of Happy Pills in America: From Miltown to Prozac 'As Matthew Smith demonstrates in this excellent study, there is arguably no more contentious childhood condition than hyperactivity or ADHD. Since the term was first introduced in the decades following the Second World War, hyperactivity has been variably explained in terms of genetic constitution, faulty parenting, an inability to cope with the pace and pressure of modern life, and increased sensitivity to food additives. Hyperactive explores debates about the biological, social and cultural contours of a condition that continues to puzzle doctors, frustrate teachers, and destroy families. It will surely be of value not only to historians of medicine, but also to the parents, teachers, psychiatrists and policy-makers involved in the daily struggle to cope with hyperactive children.' - -- Mark Jackson, Professor of the History of Medicine at the University of Exeter

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Book SynopsisExamining meningitis mainly from a bacterial perspective, but also including an overview of viral, fungal and chronic meningitis, this book describes the anatomy of the meninges and clinical signs and symptoms of this disease. Individual organisms that cause meningitis worldwide are dealt with in specific chapters, describing in detail how these pathogens interact with the human host at both a molecular and cellular level. The book provides a thorough understanding of bacterial virulence factors, adhesion and invasion mechanisms, the nature of known host cell receptors and the host cell response.Table of Contentsa: Preface 1: A History of Bacterial Meningitis from Antiquity to Modern Times 2: Anatomy of the Meninges: Structural and Functional Aspects 3: Evidence-based Clinical Examination of Meningitis 4: Viral Meningitis 5: Pathogenesis of Cerebrospinal Meningitis Caused by Neisseria meningitidis 6: Streptococcus pneumoniae Meningitis 7: Haemophilus influenzae Meningitis 8: Escherichia coli Meningitis 9: Group B Streptococcus Meningitis 10: Chronic Meningitis 11: The Pathophysiology of Tuberculous Meningitis 12: Neurosyphilis 13: Streptococcus suis Meningitis 14: Listeria monocytogenes: An Intracellular Pathogen of Monocytes and the Central Nervous System 15: Meningitis in Neuroborreliosis 16: Nosocomial Meningitis 17: Inflammation in the Subarachnoid Space

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Book SynopsisHow does a polar bear pooping on a rug turn into a lesson on Alzheimer’s behaviors of paranoia and hallucinations? Or a pregnant aunt turn into a lesson about long-term care decisions? The innocent dialogue and anecdotes the author has recorded for years between her and her grandchildren serve as introductions – and lessons learned – to managing the daily responsibilities in Alzheimer’s care. These poignant stories and insightful perspectives offer a fresh approach in understanding the disease. Thought-provoking, humorous, and endearing, this book will have you experiencing the journey of Alzheimer’s disease in a most light-hearted and non-threatening way, so much so that you will hardly realize how much knowledge and how many skills you are acquiring along the way. From understanding the components of the disease, to discovering various ways to communicate, to coping with difficult behavioral expressions; from weaving through all the emotions experienced by the caregiver, to understanding person-centered care, to the importance of social engagement, and much more, this book is a vital and handy resource for anybody affected by Alzheimer’s disease.Table of ContentsFOREWORD PREFACE Chapter 1: A Year of Learning Everything; Years of Losing Everything Learned Chapter 2: “I Know EVERYTHING, NoNo!” Getting Educated about the Alzheimer's Disease Journey Chapter 3: “It's Not A Hamburger Without a Bun” Getting the Correct Alzheimer's Diagnosis Chapter 4: “I'm Pretty Good” - The Practice of Caregiving Chapter 5: “Is That a Horsie in Your Hand?” Communication and Listening Skills Chapter 6: “LIAR, LIAR!” When What They Say Hurts Chapter 7: “The Polar Bear Poops on the Rug” Paranoia and Hallucinations Chapter 8: “You Gotta Sleep With Your Friend” Alzheimer's Sleep, Sundowning and Wandering Patterns Chapter 9: “I Don’t Take a Bottle” Agitation and Aggression & Person-centered Alzheimer's Care Chapter 10: “Let's Dance, YaYa!” The Importance of Activities for Individuals with Alzheimer's Disease Chapter 11: “It’s Their Business" - Dignity and Respect and the Dining Experience Chapter 12: And Then There's Collin's little sister, Brynn The Decision for Long-Term Care Chapter 13: “You Should Be Spending More Time with Me” Overcoming Guilt (and other emotions of caregiving Chapter 14: “Needing a Little Something More” Respite Care and Alzheimer's Chapter 15: “Did the Horses Do Something Wrong?” Environment Matters in Alzheimer's Care Chapter 16: “God Never Prays Back” Spirituality: God IS "Praying back" with the Individual with Alzheimer's Chapter 17: “Mommy Will be Back!” Necessary Attachments and Detaching Chapter 18: “It Doesn't Work That Way” There’s a Fixer in all of us! Chapter 19: “There's More to Alabama than Football!” Looking at the Person with Alzheimer's Disease Chapter 20: “After Everything I've Done for You...” A thank-less job Chapter 21: “A Funeral is a Really Sad Party!” The dual experiences of Alzheimer's disease and death Chapter 22: “THIS IS ME!” - The Greatest Showmen are Individuals & Caregivers affected by Alzheimer’s Disease Chapter 23: “You Gotta Use Your Brain!” Reducing the Risk of Alzheimer's Disease Chapter 24: “Life is Unfair!” - The Injustices of Alzheimer’s disease Chapter 25: “What's Next, Daddy?” The Future of Alzheimer's disease Epilogue

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Book SynopsisThis book explores cultural and historical aspects, as well as the causes and functions that self-injury serve. Therapy with people who self-mutilate is discussed in detail. A framework is provided for professionals facing this behaviour at work.Trade Review'Links are made to women's powerlessness in society , their culturally determined dissatisfaction with their bodies and their repression of anger. The important point is made in settings where individual autonomy is restricted, such as prisons where male self-harming behaviour begins to resemble that of women's. Could readers of this book actually find themselves better able to deal with people who self-harm? Quite possibly - I feel that there is much of immediate practical value, in particular the persuasive argument that for many people, self-harm can be a genuine coping mechanism which brings relief from an unbearable mental state. ' Probation Journal 'This book is extremely well researched and written. The authors have managed that difficult balance between making sure that all their information is appropriately referenced and keeping the book readable. It is more than readable, it is a book that is really interesting to read...' Professional NurseTable of Contents1. The parameters of self-injury and setting the scene. 2. The cross-cultural and historical context of self-injury. 3. Self-injury and social forces. 4. The origins and functions of self-injury for individuals. 5. Principles of working with people who self-injure. 6. Working in particular settings with people who self-injure. 7. Therapy with people who self-injure.

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Book SynopsisThis book is intended both as a comprehensive review and discussion of the major studies of language development and functioning in mentally retarded (MR) persons over the last fifty years, and as an exploration of a number of important issues in this field. *The use of the term 'mental retardation' is in line with the recommendations of the American Association on Mental Retardation and other relevant organisations.Table of ContentsOutline and Rationale. Historical Sketch. Early Speech Studies. Early language Studies. More Theoretically Oriented Studies. Lenneberg's Studies. Psycholinguistically Oriented Work. Intervention Studies. IQ. Sex Social Class. Syndrome Considerations, and The Specificity Question. Iq, Levels of Mental retardation, and Language. Sex Differences. Social Class Differences. Syndrome considerations. The Specificity Question. Exceptionality and Language modularity. Exceptional Language Development in Mental Retardation. Dissociative Tendencies in Typical Mentally Retarded Subjects. The delay-difference Question. The Cognition-language Question. Language modularity. Language Development and Functioning. The Critical Period Question. Prelinguistic Development. Speech. Lexical Development. Thematic Semantics and morphosyntactic Regulations. Adult-child Interaction and The Development of language in The Mentally Retarded. Language in Mentally Retarded Adults. Ageing and Language in Mental Retardation. Language Remediation. Dimensions and contents. The Efficiency Issue. Alternative and Augmentative Systems of communication. Literary Training. Memory and Language. Computer-enhanced language Intervention. Perspectives.

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Book SynopsisNow published in a fully revised and updated second edition, this is an integrated and practical text for the student or the practising therapist. The authors take account of current models of language development and show the influence of these themes in relation to developmental language disorders. They also discuss current research into infant skills and emergent language and its influence on the early identification of language disorders. Drawing on their clinical experience, the authors consider at a practical level the role of the speech therapist/pathologist in the education of language handicapped children, the problems faced by speech therapists/pathologists in this area, and the strategies for intervention and management.Table of ContentsPreface to the Second Edition. Chapter 1 Characterisation. Chapter 2 Identification. Chapter 3 Prevention. Chapter 4 The Underlying Nature of Devlopmental Language Disorders - Hilary Gardner. Chapter 5 The Differentiation of Clinical Subtypes. Chapter 6 Assessment of Developmental Language Disorders - Hilary Gardner. Chapter 7 The Nature and Timing of Intervention. Chapter 8 Reflections and Future Developments. References Principal Tests Cited in Text. Glossary. Subject Index. Author Index.

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Book SynopsisThis book discusses the following topics: intracranial and inner fluid interactions the endolymph/perilymph/cerebrospinal fluid and associated disorders; non-invasive measurement of intracranial and inner fluid pressures; clinical aspects with particular reference to symptomatology, diagnosis and treatment; comparative fluid models.Table of ContentsForeword. Preface. Part 1 Intracranial Physiology. Chapter 1 The anatomy and physiology of intracranial fluids - MB Segal. Chapter 2 Hydromechanics of the intracranial and labyrinthine fluids - experimental study in cats - B Carlborg and KS Konradsson. Chapter 3 Dynamics of inner ear pressure change caused by cerebrospinal fluid pressure manipulation in guinea pigs - EO Thalen, HP Wit, JM Segenhout and FWJ Albers. Chapter 4 CSFand posture effects on transient evoked otocoustic emissions - pilot study - MA Ferguson, AC Davis and EA Lovell. Part 2 Intracranial Pathophysiology. Chapter 5 Pathophysiology of the cerebrospinal and cerebrovascular circulations - JD Pickard, S Piechnik, P Smielewski, PJ Kirkpatrick and M Czosnyka. Chapter 6 Intraoperative neurophysiologic monitoring in skull base operations - AR Moller. Chapter 7 Neurotolotgic manifestations of intracranial hypertension - A Sismanis. Chapter 8 Idiopathic normal pressure hydrocephalus: primary disorder of CSF absorption or parenchymal cerebral disease: The relevance of vascular risk factors and cerebral white matter lesions - KR Krauss. Chapter 9 Influence on the auditory system of cerebrospinal fluid loss: clinical and experimental results - A Walsted. Chapter 10 OAE and TMD recordings in ICP changes - A Ernst, T Lernarz and K Weckbecker. Chapter 11 A review of the management and current methods of investigating intracranial pressure in shunted hydrocephalics and an introduction to the tympanic membrane displacemernt test - M Samuel, RJ Marchbanks and DM Burge. Chapter 12 The application of the tympanic membrane displacement (TMD) test as part of the clinical service for hydrocephalus patients - S Flynn, RJ Marchbanks and D Burge. Chapter 13 Quantitative assessment of intracranial pressure by the tympanic memberane displacemtn test in patients with shunted hydrocephalus - M Samuel, DM Burge and RJ Marchbanks. Part 3 Inner Ear Physiology Chapter 14 Physical processes underlying homeostasis of cochlear endolymph - AN Salt and JE DeMott. Chapter 15 Cellular mechanisms of volume control in the labyrinth - P Wangemann. Chapter 16 Non-invasive perilymphatic pressure measurements using the MMS-10 Tympanic Displacement Analyser in patients with Meniere's disease - HJ Rosingh, HP Wit and FWJ Albers. Chapter 17 Modelling labyrinthine fluid dynamics - JC Andrews, D Strelioff, M Bergsneider and D Becker. Chapter 18 The effect of changes in cochlear fluid pressure on audiological measurements - AJ Phillips, GB Farrell and ARD Thornton. Chapter 19 Ionic transports in the endolymphatic sac of the guinea pig - V Couloigner, M Teixeira, P Hulin, O Sterkers, G Planelles and E Ferrary. Chapter 20 Beta-trace protein in human perilymph - G Bachmann, SE Baldus, M Nekic and O Mitchell. Chapter 21 Characteristics of infrasonic otoacoustic emissions generated by the cardiovascular system - MP Hughes and RJ Marchbanks. Chapter 22 Morphological effects of low extracellular calcium on stereociliary bundles in the guinea pig cochlea - BN Kumar, DN Furness and CM Hackney. Chapter 23 Dynamics of inner-ear pressure release measured with a double-barrelled micropipette in the guinea pig - HP Wit, EO Thalen, JM Segenhout and FWJ Albers. Part 4 Iiner-ear Pathophysiology. Chapter 24 Treatment of otolith disease concepts and new development of laser microsurgery - M Westhofen, U Mangold and W Wrollmer. Chapter 25 Posturographic correlates of peripheral and central vestibulardisorders, as assessed by electronystagmography (ENG) and the Tetrax Interactive Balance System -R Kohen-Raz, A Sokolov, A Kohen-Rax, M Demmer and M Har-El. Chapter 26 Vertigo and progressive sensori-neural hearing loss - peripheral cause or vascular compression of CN VIII? - MB Moller. Chapter 27 Acetazolamide therapy of endolmphatic hydrops audiologically monitored by low-frequency masking: case report - EA Kabudwand, D Adler, G Scholx and D Mrowinski. Chapter 28 Effects of middle ear pressure changesd on the inner ear function in Meniere's disease: a review - B Densert, S Arlinger, O Densert, K Sass and L Odkvist. Chapter 29 Tullio phenomenon: distrurbed inner ear homeostasis? - CF O'Mahoney and LM Luxon. Chapter 30 Traumatic sudden sensorineural hearing loss in children - B Kou and R Macdonald. Chapter 31 Fleeting hearing loss: reversible dysfunction of the cochlea during acute bacterial meningitis - MP Richardson, PT Rudd, A Reid and MJ Tarlow. Chapter 32 Recurrent perilymphatic fistual in patients with possible patent cochlear aqueduct: a role for cochlear aqueduct blockade: report of five cases - DJ Weider and FE Musiek. Chapter 33 Effects of the atrial natriuretic peptide (ANP) on hearing and tinnitus in patients suffering from Meniere's disease - J Lamprecht. Index.

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Book SynopsisThis book is a comprehensive guide to all major aspects of neuro-oncology care. The first section deals with the anatomy and physiology of the brain. It discusses and describes neurological assessment and examines tumours, their make-up and how they are imaged. The second part of the book looks at treatment processes, including pre- and postoperative care, surgical approaches, and the role of radiotherapy and chemotherapy. It examines the medications most frequently used to control symptoms, their uses and side-effects.Table of ContentsAnatomy and Physiology of The Nervous System, Kate Weldon. Neurological Assessment, Sally Aucken and Belinda Crawford. Pathological and clinical Aspects of CNS Tumours, Geoffrey Sharpe. Clinical Neuro-imaging, Juliet Britton and Nirginia Ng, Neurosurgery,Clare Addison and Sarah Shah. Radiotherapy, Douglas Guerrero. Chemotherapy, Douglas Guerrero, Sue Sardell and Frances Hines. Medication in The Symptom Management of CNS Tumours, Christopher Evans and Douglas Guerrero. Multidisciplinary Teamwork, Sarah N. Fisher. Altered Body Image, Mave Salter. Psychological Support, Sue Kibler. Future planning of Care, Mave Salter.

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Book SynopsisThis book is the first to provide comprehensive coverage of the communication impairments that occur in association with multiple sclerosis. It covers not only the more widely recognised motor speech disorders seen in association with this condition, but also the more recently identified language disorders reported to occur in persons with diseases of the cerebral white matter. A full description of the neuropathophysiology, epidemiology, aetiology, clinical manifestations and medical treatment of multiple sclerosis is also included.Table of ContentsNeuropatholophysiological Basis of Communication Disorders in multiple Sclerosis. Perceptual Features of Dysarthria in Multiple Sclerosis. Acoustic Features of Dysarthria in Multiple Sclerosis. Articulatory and velopharyngeal Dysfunction in Multiple Sclerosis. Laryngeal and Respiratory dysfunction in Multiple Sclerosis. Treatment of Motor Speech Disorders in multiple Sclerosis. Language Disorders in Multiple Sclerosis. High-level language. Naming and Discourse Abilities in Multiple Sclerosis. Subgroups of multiple Sclerosis Patients Based on Language Dysfunction. Treatment of language Disorders in Multiple Sclerosis.

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Book SynopsisStroke patients continue to present a major challenge to the rehabilitation professions. In particular, the "rehabilitated" patient with a useless hand remains an all too common phenomenon. This book focuses on the sensory perceptual disturbances caused by stroke which, even if slight can be the crucial factor in poor hand function. A wide-ranging review is presented of the processes of functional reorganisation by which the brain responds to the demands posed by injury as well as by learning. An inescapable conclusion from this literature is that any therapy which aims to harness these processes for the restoration of function after stroke needs to engage the patient's attention and motivation. This is followed by a detailed description of the method of Sensory Re-education developed by the author through long experience with patients and culminating in a clinical trial which establised its effectiveness. While the book is intended primarily for physiotherapists and occupational therapists, it contains much to interest all who are concerned with brain function in health and disease, including neurologists and neuropsychologists, as well as stroke patients and their families. Contents Introduction The Challenge: Stroke and its Aftermath The Effectiveness of Therapy The Quest for a Different Approach Sensory Loss in Stroke: Sensory Testing and the Frequency and Types of Deficit The Functional Implications of Sensory Loss The Theoretical Basis of Sensory Re-education: Sources Peripheral Nerve Lesions; Central Lesions Guide-lines for Intervention Contributions from Psychology: Attention; Motivation The Essentials of Sensory Re-education: The Focus on the Hand The Therapeutic Relationship The Protocol for a Sensory Task Summary The Curriculum I: How to Use the Curriculum Lessons in Touch The Curriculum II: Lessons in Proprioception Lessons in the Recognition of Objects and Their Qualities Suggestions for Homework Validation of the Method: Theoretical Considerations A Controlled Trial The Next Step Wider Applications: Sensory Problems in Standing and Walking After Stroke Cerebral Palsy Other Conditions Wider Applications Conclusion

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Book SynopsisThis book has been produced on behalf of the National Association of Neurological Occupational Therapists (UK) and is intended to guide newly-qualified occupational therapists (and those new to the field of stroke) through the complexities of treating people following stroke. Writen and edited by practising occupational therapists, the book acknowledges the many different techniques that may be used in stroke management and the scope of the occupational therapy role in the UK. This book will provide occupational therapists with the foundations for effective occupational therapy in stroke rehabilitation.Written in a user-friendly style, the book's chapters are presented in a form that enables the therapist to review the subject prior to assessment and treatment planning. Complex problems are grouped together to avoid confusion. This book encourages therapists to use their skills in observation and problem solving, adapting and building on the techniques seen on clinical placement and taught in college.Table of ContentsIntroduction. Definition of Stroke. Causes of Stroke. Classification of Stroke. International Classification of Impairment. Disabilities and handicap. Medical Investigations. Damage That can Occur in Different Areas of the Brain. Early Management. OT. The Stroke Wheel. Role of OT. Frames of reference/models. Treatment Approaches. Initial Assessment - (general, sensation, Functional, Goal Setting). Standardised Assessments. Standardised adl Assessments. Positioning, Equipment (wheelchairs, Adl, Splinting). Management of Motor/sensory Deficits. Therapeutic Aims. Management Principles (physical, Self-care Activities, Instrumental Activities, Remedial Activities). Management of Cognitive/perceptual Deficits. Cognitive Deficits. Perceptual deficits. Resettlement. Mood. Fatigue. Resuming Sexual Activity. Leisure rehabilitation. Work. Driving. Stroke Education. Therapeutic Challenges. Pusher syndrome and Overuse. Shoulder/hand Syndrome. Dyspraxia, Dysexecutive Function. Ataxia. Speech and Language Deficits. Dysphagia. Evaluation. Standards of stroke Care. Methods of Recording OT Intervention. Evidence-based Practice. Outcome Measures. New Approaches/way Forward. Isokinematic Training. Ensuring best Practice (OT Clinical Audit, OT Research). Competency Framework. Glossary and Bibliography. Definitions. References. Useful Books. Useful Assessments. Useful Addresses. Stroke Association Publication List.

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Book SynopsisThere is a surfeit of writing about evidence-based practice which is often difficult to relate to the actual treatment of patients. This book however, starts with real patients and their problems, then turns to specialist clinicians from different philosophies describe how they would treat that patient. This means that the contents are directly relevant to clinical practice. The authors have provided a generous list of references to support their choice of treatment. The book will be of interest to a wide audience including physiotherapy clinicians and researchers, others in the health care teams treating patients with neurological conditions and managers organising these services. It will also be valuable for both undergraduate and postgraduate therapists studying neurology. Contents: Section One: Single Incident Neurology - Case Reports: stroke; head injury; incomplete spinal injury; complete spinal injury. Section Two: Progressive Disorders - Case Reports: Parkinson?s Disease; Multiple Sclerosis.Table of ContentsSection 1 - Single incident neurology Case Report: Mrs LM (Stroke) 1 Early rehabilitation-Part 1 2 Early rehabilitation-Part 2 3 Later Rehabilitation Case Report: Mr ND (Head Injury) 1 Respiratory Management 2 Rehabilitation-Part 1 3 Rehabilitation-Part 2 Case Report: Mr SP (Complete spinal lesion) 1 Tratment and Management Case Report: Mr PL (Incomplete Spinal Cord Injury) Section 2 - Progressive Disorders Case Report: Mr LH (Parkison's disease) 1 Treatment and management-Part 1 2 Treatment and Management-Part 2 Case Report: Mrs LW (Multiple sclerosis) 1 Treatment and management-Part 1 2 Treatment and management-Part 2

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Book SynopsisThis comprehensive resource examines all aspects of the care of the patient with Multiple Sclerosis (MS). It focuses on the themes of: The importance of patient-centred nursing Comprehensive assessment of the person with MS The wide variation in the course of MS The role of the nurse The early part of this book examines the theory of MS i.e. the pathophysiology, the epidemiology, the types of MS and the various diagnostic tests. Practical aspects are included particularly in caring for someone who is going through the process of being diagnosed as having MS. There follows an exploration of the theory and practice of interferon therapies and a review of symptom management using case studies and vignettes. The later chapters discuss the complications of severe MS and the implications for the family and nurse in caring for someone who is severely disabled. Megan Burgess, a Clinical Nurse Specialist at the Hope Hospital, Salford has used her years of practical experience to produce an authoritative, single-volume library that will be essential reading for nurses in hospital and in the community who come in contact with people with MS.Table of ContentsNatural History of MS. Diagnosing MS. Types of MS. Disease Modifying therapies. Symptoms and Their Treatments. Bladder and Bowel Symptoms. Sexuality and Pregnancy. Cognitive Dysfunction and Depression. Patient-centred Nursing. Health Promotion and Self-management. Complications and Management of Severe MS. The Future for People With MS.

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Book SynopsisThis book describes and discusses the assessment and treatment techniques applied by Occupational Therapists (OTs) to sufferers from Multiple Sclerosis (MS).The text begins with basic information about MS and follows this with suggestions for assessment and treatment. Then the specific issues of work, fatigue, leisure, mobility and the home are considered in detail. The needs of people who reach the later stages of the disease are discussed, as are the needs and concerns specific to carers of those with MS. Contact details are provided for many of the services and agencies mentioned in the text. Insight into the impact of MS on people's lives is provided by individuals with MS.Table of ContentsMultiple Sclerosis. Assessment. Management. Work and Multiple sclerosis. Fatigue in Multiple Sclerosis. Leisure for People With Multiple sclerosis. Mobility for People With Multiple Sclerosis. Multiple Sclerosis and The Home. Continuing Care. Caring for People With Multiple Sclerosis. Contact Addresses. References. Index.

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Book SynopsisParkinson's Disease is a common neurological condition which nurses need to be equipped to manage. The aim of this book is to provide nurses with a readable and succinct text that will help them to deliver evidence-based, patient-centred nursing care for patients and their families with Parkinson's disease. This book discusses the common difficulties that are encountered in patients' day-to-day lives and gives practical advice on how the nurse can help and support patients and their families.Table of ContentsPathogenesis of Parkinson's Disease Lesley Swinn. Diagnosing parkinson's Disease Peter Hagel and Lesley Swinn. Drug Treatment of Parkinson's disease Jacqui Handley. Motor Fluctuations Lesley Swinn. Apomorphine Kirsten turner and Lesley Swinn. Surgical Treatment for Parkinson's Disease Carole Joint and Lesley Swinn. Bladder, Bowel and Sexual Function in Parkinson's disease Collette Haslam and Ranan Dasgupta. Sleep and Parkinson's Disease Ellie Borrell. Communication and Swallowing in Parkinson's Disease Gabrielle Irwin. Affective Disorders in Parkinson's Disease Carolyn Noble. Assessing The Needs of People With Parkinson's Disease Jacqui Handley. Progressive Supranuclear palsy Tess Astbury and Maggie Rose. Multiple System Atrophy Catherine Best. Parkinson's Disease Society Barbara Cormie. Parkinson's Disease Nurse specialist Association Karen Vernon. Future Developments in Parkinson's disease. Peter Hagel.

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Book SynopsisThis engaging book will serve as an introductory text in neuroscience. It conveys important ideas in neuroscience without overburdening the student with unnecessary detail. Drawing from his 35 years of teaching experience of teaching at Oxford University, the author concentrates on concepts and observations that students find difficult, amusing, interesting or exciting. Starting with a brief history of neuroscience, it covers cellular and biophysical aspects, sensory systems, motor systems, the hypothalamus, the automatic nervous system, learning and memory and speech and reading.Table of ContentsPreface. Chapter 1. Historical introduction. Chapter 2. Structure of the brain and central nervous system. Chapter 3. Physiological techniques. Chapter 4. Excitable membranes. Chapter 5. The neuromuscular junction. Chapter 6. Central neurotransmission. Chapter 7. Muscle. Chapter 8. Sensory systems. Chapter 9. Visual psychophysics. Chapter 10. The eye. Chapter 11. Central visual processing. Chapter 12. Hearing: the auditory system. Chapter 13. Somatosensory system. Chapter 14. Pain. Chapter 15. Smell and taste. Chapter 16. Vestibular system. Chapter 17. Position and movement sense. Chapter 18. The posterior parietal cortex: active touch and active sight. Chapter 19. Motor control. Chapter 20. Muscle receptors and spinal cord reflexes. Chapter 21. Posture and locomotion. Chapter 22. The cerebellum. Chapter 23. The basal ganglia. Chapter 24. The motor cortical areas. Chapter 25. The prefrontal cortex. Chapter 26. Eye movements. Chapter 27. Extrapyramidal pathways. Chapter 28. The electroencephalogram: reticular system, sleep and arousal. Chapter 29. Drives, reward, emotions and mental disorder. Chapter 30. The hypothalamus: body weight, temperature and fluid balance. Chapter 31. Autonomic nervous system. Chapter 32. Development, learning and memory. Chapter 33. Hemispheric specialization: handedness, speech and reading. Glossary. Bibliography. Index.

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Book SynopsisProfiling has been acknowledged as a major contribution to the treatment of language disorder. First developed with reference to grammatical disability, profiling is extended in this book to cover segmental phonology, prosody and semantics. The book also includes a revised version of the grammatical profiling procedure, LARSP. For this second edition of the book all the existing material has been updated. In addition there is a new chapter, entitled "Putting Profiles into Practice", which contains extracts from case studies and several guidelines for teaching and therapy.Table of ContentsPreface to second edition. Preface to first edition. 1. Linguistic profiles. 2. LARSP (language assessment, remediation and screening procedure). 3. PROPH(Profile of phonology). 4. PROP (prosody profile). 5. PRISM (profile in semantics). 6. Putting profiles into practice. Bibliographical notes. Index.

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Book SynopsisThe functional approach to the treatment of aphasia is embodied in the methods and techniques of Promoting Aphasic's Communicative Effectiveness (PACE), which has had an international influence on the way therapists approach the rehabilitation of aphasia patients. However, there is a shortage of research into the approach and little up-to-date practical guidance on its application. D. Carlomagno's concise book aims to provide a guide to the use and efficacy of PACE methodology which should be useful for aphasia therapists.Table of ContentsForeword. Preface. Acknowledgements. Introduction. Chapter 1 Communicative competence in aphasia andtherapies for improving communication. Chapter 2 PACE approach: a comprehensive theory for a pragmatically oriented method of treating aphasic disturbances. Chapter 3 PACE therapeutic practice. Chapter 4 Evaluating communicative effectiveness of patient (and therapist's behaviour) in the PACE setting. Chapter 5 The effectiveness of PACE therapy: does it promote the communicative effectiveness of aphasic subjects? Chapter 6 General conclusions. References. Index.

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Book SynopsisBring out the best in each person with dementia each day with more than 140 versatile, easy-to-implement Best Friends activities. Thousands of caregivers around the world know that providing Best Friends' care improves the quality of life of people with dementia by building on the essential elements of friendship; respect, empathy, support, trust, humor, and sharing time together. Using the Best Friends approach to activities, anyone on staff can turn any interaction with a resident or client into an activity that satisfies essential physical, emotional, and spiritual needs. Each activity contains suggestions for personalizing the activity and matching it to the remaining strengths of the individual to ensure success and reduce challenging behaviors. The Best Friends Book of Alzheimer's Activities is chock full of inspiring and innovative ideas on how to: convert everyday activities into those with ""knack""; create new activities out of tried-and-true activities; provide activities between structured programs/events; increase self-esteem; adapt activities for people with late dementia; provide opportunities for connecting to others; create intergenerational experiences; use the person's life story in any activity; make activities out of personal care; conduct activities specifically for men; fill evening hours to alleviate sundowning; provide ""take-away"" activities for family caregivers to use at home; incorporate exercise into activities; use the Internet to expand and enrich activities. Many activities can be conducted spontaneously, with simple props, engaging older people in meaningful activity for extended periods. Best Friends activities are adult-oriented and flexible enough for staff and residents to add their own ideas. Special features include a list of the latest and most effective resources for activity professionals and helpful tips on communicating with people with dementia.

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Book SynopsisThe massive convergence of information about cavernous malformations has been synthesized in this volume by experts in the field of pathology, neuroradiology and neurosurgery. Cavernous Malformations represents state–of–the–art knowledge about this lesion and the spectrum of opinion about its nature, clinical behavior and management strategies. Highlights of Cavernous Malformations: Definition and pathologic features Epidemiology Diagnostic imaging Epilepsy Hemorrhage Conservative management Surgical intervention Microsurgical treatments Spinal cavernous malformations Pediatrics Radiotherapy (Distributed by Thieme for the American Association of Neurological Surgeons)Table of ContentsDefinition and Pathologic Features; Epidemiology of Cavernous Malformations; Clinical Spectrum and Natural Course; Diagnostic Imaging of Cavernous Malformations; Cavernous Malformations and Epilepsy; Cavernous Malformations and Hemorrhage; Conservative Management; Indications for Surgical Intervention; Microsurgical Treatment of Supratentorial Lesions; Microsurgical Treatment of Infratentorial Malformations; Extra Axial Cavernous Malformations; Spinal Cavernous Malformations; Lesions Mimicking Cavernous Malformations; Cavernous and Other Cryptic Vascular Malformations in the Pediatric Age Group; Radiosurgery of Cavernous Malformations and Other Angiographically Occult Vascular Malformations; Conceptual Overview and Management Strategies

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Book SynopsisThis work aims to bring together a wide-ranging set of clinical linguistic case studies covering all levels of linguistic analysis and demonstrating the application of more than one level of linguistic analysis to individual cases. It focuses on "patient-driven" cases. The authors aim to demonstrate the collaborative nature of applied linguistics by illustrating the kind of service that speech and language therapists may reasonably ask of linguists, without feeling that they need have expertize in this area themselves. The case studies include a representative range of communication disorders and involve a wide range of areas of linguistics and phonetics. Most of the studies incoporate complementary analysis at several linguistic levels, and involve a wide variety of analytical techniques including standard assessments and profiling procedures, instrumental and computational procedures, and improvised materials tailored to the specific nature of individual cases.Table of ContentsPart 1. Preliminaries. Principles of Clinical Linguistic Analysis. Part 2. Developmental Communication Disorders. Intransigent Articulation disorder. Using Electropalatography to Assess and Remediate Misarticulated fricatives. Cleft Palate. Perceptual and Instrumental Analysis of a phonological System. Global Language Delay. Analysis of a Sever Central auditory Processing Deficit. Down's Syndrome. Linguistic Analysis of a Complex language. Conversational Disability. Assessment and Remediation. Part 3. Acquired Communication Disorders. Acquired Dysarthria. Segmental Phonological and Prosodic Analyses. Acquired Speech Disorder. Differential Diagnosis Using perceptual and Instrumental Analysis. Aphasia. Assessment and Remediation of a speech Discrimination Deficit. Aphasia. Conversation Analysis of a Non-fluent aphasic Individual. Closed Head Injury. Assessment and Remediation of Topic bias and Repetitiveness.

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Book SynopsisThe core elements of narcissism concern the dificulty individuals encounter with the separating process and their use of the mechanism of splitting. Through the work of American thinkers (such as Kernberg and Kohut) on the advancement of the understanding of narcissistic disturbances is well known, the contribution of the British school has had a comparatively low profile. This book seeks to redress the balance by providing an up-to-date presentation of the work in this area of British psychotherapists and psychoanalysts of different theoretical orientations - contemporary Freudian, Kleinian and independent.Table of ContentsPart 1. Overviews, a Brief History of Narcissism, David Smith. The current State of Clinical Work - Diagnosis, Treatment and Outcome, Judy Cooper and Nilda Maxwell. Part 2. Narcissism in The Life Cycle, Early Problems in mother-child Separation as a Basis for Narcissistic Disturbance, Maria Pozzi. Narcissistic Vulnerability in Adolescence, Sara Flanders. Narcissism and adolescence, Peter Wilson. Between Narcissistic and More Mature Object Relating - Narcissism and The Couple, Stanley Ruszczynski. Narcissistic Displacement in childbearing, Joan Raphael-leff. Narcissism in Ageing, Anne Zachary. Narcissism and Bereavement, Hazel Danbury. Part 3. Clinical Aspects of Narcissism, The search for a Primary Object - Making and Breaking in The Treatment of narcissism, Judy Cooper and Nilda Maxwell. "I am Glad I am Late", Daniel Twomey. Destroying The Knowlege of The Need for Love - Narcissism and perversions - David Morgan. Addiction as a Narcissistic Defence - The importance of Control Over The Object, Liz Good.

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Book SynopsisClinics in Developmental Medicine No. 162 The Research Programme on Shaken Baby Syndrome in Edinburgh is internationally recognised for its prominent ongoing research into the epidemiology, bio-mechanics, primary and secondary brain insults, neuroradiological aspects, medical-social aspects, and neurodevelopmental and neuropsychometric sequelae of shaking a baby. In this book, a highly distinguished team of experts from the programme present the clinician with the latest findings on the syndrome, covering the diagnosis of the syndrome itself and the long-term disability that results which, unlike other forms of child abuse associated with psychological scars, is also associated with a high degree of life-long physical and intellectual disability. This will be invaluable reading for all professionals concerned with diagnosing and treating this syndrome.Trade Review"Well written and comprehensive … .Throughout the book, there are many excellent pictures (most from real cases with no patient identifiers), illustrations, tables, and even several flow diagrams. The chapters on neuroimaging are very useful and would be of benefit to event the most accomplished neuroradiologist." (Journal of Child Neurology, November 2007)Table of ContentsPreface Martin Bax; 1. Epidemiology John Livingston; 2. Mechanisms and clinical presentation Robert Minns; 3. Haemorrhagic retinopathy of shaken injury: clinical and pathological aspects Andrew Parsons, Kristina May and Robert Doran; 4. Neuroimaging in acute and subacute non-accidental head injury: ultrasound and CT Tim Jaspen; 5. Initial and sequential MRI in non-accidental injury Maeve McPhillips; 6. Skeletal injuries in non-accidental injury Stephanie McKenzie; 7. Secondary brain insults Peter Andrews; 8. Early post-traumatic seizures Karen Barlow and Robert Minns; 9. Mechanism and management of subdural haemorrhage Jonathan Punt; 10. Neurodevelopmental and neuropsychological outcome Karen Barlow; 11. Neuropathology of non-accidental head injury Jeanne Bell; 12. Child protection and prevention Jacqueline Mok; 13. Conclusions Robert Minns and Keith Brown; Glossary of terms Nina Punt; Index.

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Book SynopsisClinics in Developmental Medicine No. 170 Elimination disorders (nocturnal enuresis, urinary incontinence and encopresis) are among the most common disorders of childhood. Some disorders are primarily genetically determined, in others environmental factors predominate. Also, the rate of comorbid behavioural disturbances differs greatly from one syndrome to another. Because of this variety and heterogeneity, each disorder requires specific approaches in assessment and treatment. This book provides an evidence-based overview of functional elimination disorders. It draws on the standardisation and terminology suggested by the International Children's Continence Society. Short case vignettes, photos and line drawings, as well as questionnaires and charts are provided. To enable a quick orientation for clinical purposes, each chapter is followed by summaries, guidelines and diagrams. It will be of interest to all professionals working in the field.Trade Review"[This book] is a bit of a treasure trove. It is difficult to imagine a better-researched volume ... .It is jam packed, even impacted with good bits. It is fantastic to have access to so much information, which is so clearly authoritative but sometimes a bit tricky to navigate. If you are interested in this area you will cherish this book as a rock." (Disease in Childhood, March 2007)Table of ContentsPreface; List of abbreviations; 1. Introduction; 2. Classification and definitions; 3. Normal bladder and bowel development; 4. General principles: assessment; 5. General principles: treatment; 6. Nocturnal enuresis; 7. Functional urinary incontinence; 8. Organic urinary incontinence; 9. Functional faecal incontinence (encopresis); 10. Organic faecal incontinence; 11. Conclusion; appendices, references; Index.

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Book SynopsisClinics in Developmental Medicine No. 171 The last 10 years have seen major advances in the scientific understanding of ADHD. This book builds on them to provide a practical, comprehensive and evidence-based approach to clinical work with ADHD and hyperkinetic disorder, and to similar problems in people with complex neurodevelopmental disabilities. This is a book for professionals of all kinds who deal with hyperactive children and people with ADHD. It explains the science base of understanding it and gives practical step-by-step instructions on how to treat it - including informative leaflets for parents and teachers.Table of ContentsPreface. Chapter 1: Clinical and Epidemiologicl Foundations. Chapter 2: Biological Foundations. Chapter 3: Diagnosis and Assessment. Chapter 4: Psychological Assessment. Chapter 5: Medical Investigations and Tests. Chapter 6: Making a Case Formulation: Differential Diagnosis and Recognizing Comorbidity. Chapter 7: Education and Advice. Chapter 8: Pharmacotherapy in ADHD. Chapter 9: Behavioural and Cognitive Approaches. Chapter 10: ADHD and Sleep Problems. Chapter 11: Aspects of Medical Management. Chapter 12: ADHD in Preschool Children. Chapter 13: Hyperactivity Disorders in Children with Mental Retardation. Chapter 14: The Clinical Assessment and Treatment of ADHD in Adults.

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