Neurology and clinical neurophysiology Books

2835 products


  • Orphan Drugs in Epilepsy

    John Libbey Eurotext Orphan Drugs in Epilepsy

    15 in stock

    Book SynopsisOver half of epilepsies start before the age of 20 years and nearly 25% of them are refractory. A tiny proportion of them are even labelled a rare illness (ie: one affecting less than 200,000 people in the United States or less than 5 out of 10,000 people in the European Union). For these patients, two problems in their management arise: In children, seizures affect an immature brain and can impact its development. It is therefore essential to treat them so that brain development continues as normally as possible. The rarity of these syndromes does not encourage the pharmaceutical industry to invest in research. Therefore, there are few drugs available. However, a few target syndromes with a particularly unfavourable diagnosis. This work outlines 6 molecules in detail that are specifically used in epileptic encephalopathies. Every aspect of these molecules is discussed, including drug development, indication, efficacy, cost, etc. Drafted by international experts in the field of epileptology, it provides all the necessary information on orphan drugs and their clinical use.

    15 in stock

    £27.89

  • John Libbey Eurotext New Diagnostic & Therapeutic Tools in Child

    Out of stock

    Book SynopsisThis book provides a comprehensive review and update of the newest diagnostic and therapeutic tools in paediatric neurology. Special attention is paid to neuroradiologic and neurophysiologic techniques and to their clinical application, with guidelines and suggestions on how an integrated approach can be used to reach diagnosis. Some of the chapters focus on the new-born infant and the first years of life, highlighting the most appropriate MRI, clinical, and EEG techniques to investigate the developing brain. State-of-the-art techniques used in older children are also presented that afford a better understanding of the correlation between function and brain structure in young patients with brain lesions. New genetic discoveries are particularly emphasised, as is the possibility of performing accurate phenotype -- genotype correla-tion by combining the latest methods, such as muscle MRI and genetic information, in order to identify MRI patterns associated with specific genetic disorders. In all chapters an effort is made to combine technical data with clinical applications in order to show, when possible, how these novel procedures can also be used in rehabilitation. This book will be of interest to paediatricians, paediatric neuro-logists, neonatologists, and to all those who are involved in the diagnosis and care of children with neurologic disabilities.

    Out of stock

    £999.99

  • Brain Lesion Localization & Developmental

    John Libbey Eurotext Brain Lesion Localization & Developmental

    1 in stock

    Book SynopsisThe aim of this publication is to demonstrate the effect of the neural networks on cognitive functions and behavioural patterns during the development phase of a child. Taking as a basis the previous publication in this series dedicated to brain lesion localisation and development, this time it is by examining in particular the frontal lobe, limbic system (hippocampus and amygdala) and visuo-cognitive system that this book looks at the close links between the neural networks and the future development of visual, cognitive and functional capacities. The section on the frontal lobe concentrates on anatomy, mirror neurons, memory, executive functions, the neuropsychology of frontal lobe epilepsy and the resolution of social problems which can occur as a result of brain damage. The part on the limbic system looks at neuro-anatomical organisation and the core functions of the hippocampus and amygdala, problems of language, music, emotions or autism. Finally, the section dedicated to the visuo-cognitive system summarises the visual field problems associated with focal lesions, the correlation with neuro-imagery and visual impairment in children born prematurely.

    1 in stock

    £55.24

  • Paediatric Neurological Disorders with Cerebellar

    John Libbey Eurotext Paediatric Neurological Disorders with Cerebellar

    1 in stock

    Book Synopsis

    1 in stock

    £51.84

  • Neurobiology, Diagnosis & Treatment in Autism: An

    John Libbey Eurotext Neurobiology, Diagnosis & Treatment in Autism: An

    4 in stock

    Book SynopsisAutism is an extremely complex neurodevelopmental disorder that is expressed in a spectrum of phenotypes and is characterised by impaired reciprocal social communication and stereotyped patterns of interests and activities. Its aetiopathogenesis remains poorly understood. This exhaustive synthesis discusses various aspects: A focus on the neurobiology of autism: the candidate genes implicate an involvement of numerous brain regions and a concomitant malfunctioning of neurotransmitter, immunologic, and other mechanisms; The most incisive rehabilitation models in their original formulation and the results achieved with the same or similar protocols in Italian centres (understanding, language therapy, social skill training; The psychopharmacologic options for the condition of autism per se and for its associated, very frequent, comorbidities. It suggests a potential influence on professional practice and enables an up-to-date approach to effective diagnosis and treatment.

    4 in stock

    £51.84

  • John Libbey Eurotext Epileptic Encephalopathies: & Related Syndromes

    Out of stock

    Book SynopsisAlthough Epilepsy in children is often considered as a benign condition with possible recovery in adolescence, most cases are accompanied by serious disturbances of the cognitive functions. Epileptics encephalopathies represent the most dramatic section of paediatric neurology. In most cases, children develop severe frequent polymorphic seizures, permanent extended epileptiform activity on the electroencephalogram and severe disturbances of higher mental functions. In some patients, seizures may be absent but severe cognitive, behaviour and speech disturbances develop in any case. This book, written by Russian experts in the aforementioned field, is devoted to those epileptic encephalopathies when epilepsy itself is the major cause of psychomotor retardation in children. It summarises current data from the world-wide literature and authors'' long experience of practical work with patients suffering from epileptic encephalopathies. Each chapter includes a clear definition of the syndrome, its historical background, information about aetiology and pathogenesis. Maximal attention is paid to the semiology of epileptic seizures, EEG and neuroimaging data. Diagnostic criteria and differential diagnosis are presented in detail. Many sections are illustrated with histories and photos of patients with rare diseases, examples of typical changes in EEG and MRI. And of course, the treatment is provided for all forms of epileptic encephalopathies.

    Out of stock

    £999.99

  • Outcome of Childhood Epilepsies

    John Libbey Eurotext Outcome of Childhood Epilepsies

    Out of stock

    Book Synopsis

    Out of stock

    £999.99

  • Seizures & Syndromes of Onset in the Two First

    John Libbey Eurotext Seizures & Syndromes of Onset in the Two First

    2 in stock

    Book Synopsis

    2 in stock

    £64.59

  • John Libbey Eurotext Surgical Neuropathology of Focal Epilepsies:

    Out of stock

    Book Synopsis

    Out of stock

    £999.99

  • John Libbey Eurotext Cognitive & Behavioural Neurology in

    Out of stock

    Book Synopsis

    Out of stock

    £999.99

  • Pediatric Epilepsy Surgery

    John Libbey Eurotext Pediatric Epilepsy Surgery

    2 in stock

    Book Synopsis

    2 in stock

    £129.59

  • Visual Impairments & Neurodevelopment Disorders:

    John Libbey Eurotext Visual Impairments & Neurodevelopment Disorders:

    2 in stock

    Book Synopsis

    2 in stock

    £51.84

  • Progressive Myoclonus Epilepsies:

    John Libbey Eurotext Progressive Myoclonus Epilepsies:

    5 in stock

    Book SynopsisProgressive myoclonus epilepsies are a group of rare genetic diseases. The onset generally occurs around puberty in otherwise healthy children. They all involve myoclonus and epilepsy but then differ depending on the different symptoms that are related. The outlook of these diseases is nearly always unfavourable and treatment only focuses on symptoms. Much planning will be needed to improve the quality of life for these children who will gradually become over time more and more severely disabled. Among these diseases, the most notable is Unverricht-Lundborg disease and Lafora disease, among others. However, the genetic mechanism of these diseases is simple and has been perfectly identified over time thanks to advancements in scientific discoveries. Hope lies in gene therapy, which in the near future will most likely be able to optimise treatment and even cure these children. This book addresses the situation by relying on clinicians descriptions, studies led by biologists on genetic variations and mutations and the work carried out daily by numerous scientists researching into treatment. By retracing the history of these diseases, from discovery and identification of mutated genes to the review of syndromes they encompass, this book marks the path we have travelled but also the distance we have yet to go.

    5 in stock

    £51.84

  • Psychiatric & Behavioural Disorders in Children

    John Libbey Eurotext Psychiatric & Behavioural Disorders in Children

    4 in stock

    Book SynopsisThis report of the ILAE Child Neuropsychiatry Taskforce, Neuropsychobiology Commission, was published as an e-supplement in Epileptic Disorders (Volume 8, May 2016), educational journal of the International League Against Epilepsy. Psychiatric and behavioural problems are reported to occur in 35-50% of children with epilepsy. They affect the quality of the childrens and their families lives in a very challenging manner. The ad hoc Commissions and Taskforces of the International League Against Epilepsy are regularly following progress made in the field, also promoting a larger diffusion of existing knowledge and future research. The present report is a state-of-the-art critical review, putting together numerous data concerning topics such as epidemiology, pharmacotherapy, the effects of antiepileptic drugs and epilepsy surgery, the relationships between epilepsy and many psychiatric disorders. It also points out the specific areas in need of controlled trials, such as early diagnosis and management. This report was published as an e-supplement in Epileptic Disorders (Volume 8, May 2016), educational journal of the International League Against Epilepsy.

    4 in stock

    £31.49

  • Atlas of Electroencephalography: Awake and sleep

    John Libbey Eurotext Atlas of Electroencephalography: Awake and sleep

    1 in stock

    Book Synopsis

    1 in stock

    £121.59

  • Epileptic Syndromes in Infancy, Childhood and

    John Libbey Eurotext Epileptic Syndromes in Infancy, Childhood and

    10 in stock

    Book Synopsis

    10 in stock

    £121.59

  • Atlas of Electroencephalography Volume 3: EEG

    John Libbey Eurotext Atlas of Electroencephalography Volume 3: EEG

    1 in stock

    Book Synopsis

    1 in stock

    £111.59

  • Atlas of Electroencephalography -- Volume 2: The

    John Libbey Eurotext Atlas of Electroencephalography -- Volume 2: The

    1 in stock

    Book Synopsis

    1 in stock

    £105.39

  • John Libbey Eurotext Epilepsy and Cannabinoids

    Out of stock

    Book SynopsisThere has been growing interest in the use of cannabis-based products for the treatment of a wide range of diseases, including epilepsy. A number of studies were published during the last 5 years demonstrating efficacy of purified CBD for the control of a large spectrum of seizure-types, particularly those observed in severe childhood epilepsies, such as Lennox- Gastaut and Dravet syndromes. This book, co-authored by leaders in the field of epileptology, critically reviews recent data from clinical trials. Authors discuss issues related to pharmacology, drug interactions, efficacy, potential adverse events and long-term effects on development and behaviour. Child and adult neurologists and all clinicians contributing to epilepsy care will find useful information on the best practices, when using purified CBD for the treatment of drug-resistant epilepsies.

    Out of stock

    £999.99

  • Focal Cortical Dysplasias: New advances for

    John Libbey Eurotext Focal Cortical Dysplasias: New advances for

    Out of stock

    Book SynopsisDespite major advances in all fields, Focal Cortical Dysplasias remain a mystery. From the first description 50 years ago by Taylor and colleagues, nobody could suspect that they would become perhaps the most relevant aetiology of focal epilepsies in patients of all ages, particularly those with refractory seizures. Therefore, there is an urgent need to better understand the mechanisms of epileptogenicity and the natural course of these brain developmental lesions, to recognise their many faces, and to determine the best care. There are several unresolved issues, and framing these aspects in a straightforward way may help clinicians to be attentive to further advances in the field. Many questions need very focused approaches, from people producing knowledge that impacts patients around the world every day. Based on the art, reflection and personal views shaped by the solid experience of a large panel of experts who have worked in the field for the last decades, this book provides a clear focus on the most recent advances in basic research. Combining numerous carefully selected illustrations and very practical information on the best use of all available tools and on the optimal care for patients, this book is bound to become a reference book.

    Out of stock

    £999.99

  • Essentials of Neurology

    CBS Publishers & Distributors Essentials of Neurology

    1 in stock

    Book Synopsis

    1 in stock

    £9.38

  • Mental Diseases & Their Modern Treatment

    B Jain Publishers Pvt Ltd Mental Diseases & Their Modern Treatment

    20 in stock

    Book SynopsisThis is not just a treatise upon insanity and its varied therapeutic measures, rather it is the outcome of various years of clinical experience of a dedicated medical practitioner, who has tried to explain the nature of the disease under consideration, its causes, its tendencies and its conclusions under favourable treatment. It shall became an aid to the medical students in the acquisition of knowledge, and to the busy practitioner in the care and cure of the sick.

    20 in stock

    £10.44

  • An Introduction to Neuroaesthetics: The

    Museum Tusculanum Press An Introduction to Neuroaesthetics: The

    1 in stock

    Book Synopsis

    1 in stock

    £38.69

  • Independently Published Sleeping Babies A No Text Picture Book A Calming

    Out of stock

    Book Synopsis

    Out of stock

    £11.37

  • Nova Science Publishers Inc Aneurysmal Subarachnoid Hemorrhage: From

    1 in stock

    Book Synopsis

    1 in stock

    £138.39

  • Horizons in Neuroscience Research. Volume 50

    Nova Science Publishers, Inc. Horizons in Neuroscience Research. Volume 50

    1 in stock

    Book Synopsis

    1 in stock

    £177.59

  • 1 in stock

    £163.19

  • 1 in stock

    £138.39

  • HarperCollins Publishers Inc The Mind and the Brain

    15 in stock

    Book SynopsisA leading researcher in brain dysfunction and a Wall Street Journal science writer demonstrate that the human mind is an independent entity that can shape and control the physical brain.

    15 in stock

    £14.30

  • HarperCollins Publishers Inc Brain Body Diet

    Out of stock

    Book SynopsisThe multiple New York Times bestselling author and Harvard-MIT educated women’s health expert delivers a revolutionary 40-day program to reconnect the brain and body to prevent and reverse the myriad symptoms and diseases afflicting millions of women.Do you struggle to lose weight or to fall and stay asleep at night?Trade Review“Brain Body Diet is a wonderful guide filled with the most insightful, up-to-date information. The actions we take today will impact the brains we have in the future. The power rests in each of us and this book is an invaluable resource.” — MARIA SHRIVER, author of I’ve Been Thinking Whether you are struggling to lose weight, optimize hormones, reverse autoimmunity or heal anxiety and depression, Dr. Sara Gottfried’s Brain Body Diet has the answer. The leading authority on women’s health has delivered another absolute gem. — DALE BREDESEN, author of The End of Alzheimer’s

    Out of stock

    £15.16

  • Elsevier Science Publishing Co Inc The Evolution of Lateral Asymmetries Language Tool Use and Intellect

    Out of stock

    a huge range and FREE tracked UK delivery on ALL orders.

    Out of stock

    £74.95

  • Anxious

    Penguin Putnam Inc Anxious

    2 in stock

    Book Synopsis

    2 in stock

    £17.00

  • Oxford University Press, USA Neuroscience of Pediatric Ptsd

    15 in stock

    Book SynopsisDrs. Carrion and Weems present the first book to be published on the neuroscience of pediatric PTSD. Children who experience traumatic stress early in life are at risk of developing scholastic, social, emotional and cognitive difficulties. In this book the authors present a compelling story on how neuroscience findings explain the difficulties these children are challenged with.Table of ContentsPrologue Introduction Chapter 1: Executive Function Chapter 2: Memory Chapter 3: Emotion Processing Chapter 4: Dissociation Chapter 5: Sleep Chapter 6: Self-Injurious Behaviors Chapter 7: Comorbidity in Pediatric PTSD Chapter 8: Treatment Outcomes Chapter 9: Brain Function in Pediatric PTSD: Review and Implications

    15 in stock

    £62.70

  • Oxford University Press Brain Imaging

    15 in stock

    Book SynopsisBrain Imaging: A Guide for Clinicians is designed to provide a foundation of information necessary for those wishing to integrate brain imaging into their practice, or to those who currently review brain scans but have minimal formal training in neuroimaging. The guide covers a range of topics important to those using brain imaging, such as the strengths and weaknesses of the many different techniques currently available, the factors that may influence the use of imaging data, common pitfalls or artifacts that may be misleading to the clinician, the most appropriate techniques to use given a specific clinical question or condition, how to interpret information presented on a brain image, and also how many pathological conditions appear on a variety of brain scanning techniques or sequences. This guide also provides detailed information regarding the identification of primary brain regions, anatomical structures, systems or pathways using both two-dimensional and three-dimensional imagiTrade ReviewThis well written and eminently readable book fills the gap between the student or practitioner with a rudimentary understanding of brain imaging techniques and the complex knowledge required by specialists. Rather than over simplify, the book focuses on what is necessary to understand these techniques in the context of clinical usefulness. ... This book provides the reader with the ability to understand the usefulness and limitations of brain imaging so that studies may be ordered appropriately with a clinical question in mind and not just as an indiscriminate screening tool. * H. Terry Hutchison, M.D., Ph.D., University of California, San Francisco - School of Medicine *Table of ContentsPreface ; Acknowledgments ; Introduction ; 1: THE CLINICAL APPLICATION OF BRAIN IMAGING ; Access to Brain Imaging ; Advantages of Using Brain Imaging in the Clinic ; Clues Regarding Extent of Injury ; Clues Regarding Type of Injury ; Clues to Location of Injury or Pathology ; Clues Regarding Prognosis and Expected Functional Outcome ; Clues Regarding Time Course for Recovery ; Concrete Information for Families ; Limitations: What Neuroimaging Often Does Not Provide the Clinician ; Brain imaging does not measure a patient's functioning ; Brain imaging may not provide information about electrochemical processes ; Brain imaging does not provide direct visualization of microscopic injury ; Brain scans often do not provide information regarding the etiology of damage ; Brain scans do not treat the patient ; Showing Damage on Brain Images May Not be Recommended ; What to Do When the Patient or Family Members Ask to See the Brain Scans ; What to Request When Writing Orders for Brain Imaging ; Radiologist Reports ; Anatomy versus Functioning ; 2: VIEWING AND INTERPRETING BRAIN SCANS ; Orientation and Image Plane ; Axial or Horizontal Orientation ; Axial Reformatting with Varying Slice Angles ; Coronal Orientation ; Sagittal Orientation ; When Right Is Left and Left Is Right ; Basic Clinical Interpretation ; Appearance of Brain Tissue on Different Types of Brain Scans ; Interpreting Findings on a Variety of Scans ; Use several image types or sequences when assessing for pathology ; Know what to look for, but also be conservative in your interpretation ; Symmetry as a Guide to Interpreting Brain Scans ; Evaluating Head Position in the Scanner ; Exercise caution when using symmetry as a guide ; Ventricular Dilation and Compression ; How much ventricular dilation can a person sustain without symptoms? ; Obstructive (Noncommunicating) Hydrocephalus ; Communicating Hydrocephalus ; Normal-Pressure Hydrocephalus ; (Hydrocephalus ex vacuo) ; Transependymal Edema ; Ventricular Asymmetry ; Steroid Use ; Guide to General Appearance of Different Tissues on Brain Images ; Developmental Changes Evident on Neuroimaging ; Myelination ; Temporal Eff ects on Appearance of Brain Scans ; Use caution when assessing atrophy ; Temporal Eff ects due to Progression of an Illness ; Know what the imaging should look like before viewing it ; Diagnostic Pitfalls of Neuroimaging ; Being too Focused or Not Focused Enough ; Missing What Is Missing ; Missing Pathology in the Neutral Gray ; Stop Searching After Finding an Obvious Abnormality ; Consider All Possible Causes for a Particular "Pathological" Appearance ; Pitfalls of Knowing the Neuropathology and Anatomy of the Injury ; Quality of Brain Imaging ; DICOM Viewers ; Comparing Scans Acquired on Different Occasions ; Presentation of Simultaneous Images ; 3: IMAGING-BASED NEUROANATOMY ; Primary Anatomical Landmarks ; Ventricles ; Meningeal Layers ; Dura and Dural Reflections (Folds) ; Dural Venous Sinuses ; Arachnoid Layer ; Pia Mater ; White-Matter Pathways ; Centrum Semiovale ; Corpus Callosum ; Cingulum ; Corona Radiata ; Internal Capsule ; Optic Tract and Radiations ; Basic Anatomical Areas of the Brain ; Forebrain ; Telencephalon ; Mesencephalon ; Midbrain ; Hindbrain ; Vascular System ; Internal Carotid and Vertebral Artery Distributions to the Cortex ; Circle of Willis ; Watershed Area ; Appendix 3-1 ; 4: BRAIN IMAGING TECHNIQUES ; Image Quality ; Spatial Resolution ; Contrast Resolution ; Noise ; What Type of Scan to Use? ; Types of Imaging ; Static Brain Imaging ; Ultrasound ; Computer Axial Tomography (CAT/CT) ; Angiography/Digital Subtraction Angiography (DSA) ; Magnetic Resonance Imaging (MRI) ; Hybrid Brain Imaging ; Diffusion-Weighted MRI (DWI) ; Diffusion Tensor Imaging-Fractional Anisotropy and Tractography ; Cerebral Perfusion-Weighted MRI (PWI) ; Magnetic Resonance Spectroscopy (MRS) ; Functional Brain Imaging ; Positron Emission Tomography (PET) ; Combined Positron Emission Tomography and CT (PET-CT) or MRI (PET-MRI) ; Single-Photon Emission Computed Tomography (SPECT) ; Functional Magnetic Resonance Imaging (fMRI) ; Magnetic Encephalopathy (MEG-MSI) ; General Concerns about Clinical Use of Functional Brain Imaging ; Benefits of Using Multiple Functional Imaging Techniques for Each Patient ; 5: NEUROIMAGING OF TRAUMATIC BRAIN INJURIES ; Focal Injury, Diffuse Injury, or a Combination? ; Post-Traumatic Hemorrhages ; Epidural Hemotoma/Hemorrhage (EDH) ; Subdural Hematoma/Hemorrhage (SDH) ; Examples of Subdural Hematomas/Hemorrhages ; Subarachnoid Hematoma/Hemorrhage ; Examples of Subarachnoid Hematomas/Hemorrhages ; Intraparenchymal Hemorrhages ; Petechial Hemorrhages ; Diff use Axonal Injury ; Hemorrhagic Contusions ; Contrecoup Injuries ; Common Locations for Hemorrhagic and Nonhemorrhagic Contusions ; Subcortical Hemorrhages ; Post-Traumatic Pneumocephalus ; Post-Traumatic Hypoxic Ischemic Encephalopathy ; Laminar Necrosis due to Hypoxic Ischemic Infarction ; Second-Impact Syndrome ; Intraventricular Hemorrhages ; Post-Traumatic Vasospasm ; Intracerebral Edema ; Midline Shift and Asymmetrical Compression the of Ventricles ; Loss of Gray-White Differentiation ; Blast Injuries ; Imaging Changes over Time Following SevereTraumatic Brain Injury ; Penetrating Injuries ; Penetration by Bone or Debris ; Gunshot Wounds ; Low-Velocity Penetrating Injuries ; High-Velocity Penetrating Injuries ; Shotgun Injuries ; Nonaccidental Trauma (NAT) ; Suspected Nonaccidental Trauma but Not Nonaccidental Trauma ; 6: NONTRAUMATIC BRAIN INJURIES ; Infections of the Brain ; Meningitis ; Encephalitis and Cerebritis ; Meningoencephalitis ; Abscess ; Empyema ; Stroke and Vascular Pathologies ; Imaging Nontraumatic Hemorrhagic Strokes-Cerebral Vascular Accident (CVA) ; Hemorrhagic Cavernomas ; Bleeding Disorders Resulting in Spontaneous Hemorrhage ; Nonhemorrhagic and Embolic Ischemic Strokes ; Blockage of Venous Flow ; Loss of Internal Carotid Flow Without Stroke-Related Symptoms ; Diffuse Hypoxic Encephalopathy ; Watershed Infarctions ; White-Matter Disorders ; Multiple Sclerosis (MS) ; Acute Disseminated Encephalomyalitis (ADEM) ; Toxic Damage to White Matter ; Neoplasm ; Diffuse, Infiltrating, and Nonenhancing Tumor ; Diffuse, Infiltrating, and Contrast-Enhancing Tumor ; Encapsulated Nonenhancing Cystic Tumor ; Encapsulated Contrast-Enhancing Tumor ; Hydrocephalus due to Tumor Growth ; Neurodevelopmental Disorders ; Cortical Dysplasia ; Agenesis of the Corpus Callosum (ACC) ; Polymicrogyria ; Anencephaly ; Holoprosencephaly ; Schizencephaly ; Multiple Neurodevelopmental Conditions ; Parasitic Disorders ; 7: BRAIN ATLAS ; Index ; Index of Clinical Examples

    15 in stock

    £135.00

  • Oxford University Press Neuropathic Pain A CaseBased Approach to Practical Management

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £97.75

  • Oxford University Press Vascular Disease Alzheimers Disease and Mild Cognitive Impairment

    15 in stock

    Book SynopsisAlzheimer''s disease (AD) and vascular dementia (VaD) are commonly viewed as the first and second most common types of dementia, respectively. The traditional paradigm has been to view and treat each illness as a separate entity with a separate pathophysiology. However, clinical and pathological studies suggest that the boundary separating AD and VaD, as well as their mild cognitive impairment (MCI) analogs, is not well defined. Thus, there is increased interest in viewing these diseases along a spectrum because of the significant overlap in the characterization and diagnosis of AD, VaD, and MCI. The focus of this edited volume is to examine how AD and VaD, as well as their MCI analogs, are best viewed as a heterogeneous, intersecting, if not a continuous disease state rather than separate, distinct entities. This book examines this approach by providing empirically based evidence, reviews of the literature, and chapters by key leaders in the field and will be of interest to clinical nTrade ReviewA 'must-read,' very timely, comprehensive interdisciplinary overview illuminating the complexity of the dementia syndromes, particularly Vascular-Alzheimer spectrum disorders." -Sandra E. Black, Professor of Medicine (Neurology), Department of Medicine, Sunnybrook HSC and University of TorontoThis remarkable volume brings us the most current understanding on the undeniable role of vascular disease risk factors in both neurodegenerative and vascular dementias. Expert authors fittingly also focus on prodromal phases of the most common dementia types including mild cognitive impairment and vascular cognitive impairment. They highlight vascular disease that robustly influences relevant neuropsychological, neuroimaging as well as neuropathological substrates of dementia syndromes." -Raj Kalaria, Professor of Cerebrovascular Pathology (Neuropathology), Newcastle UniversityThere is an increasing realization that the most common neuropathology underlying dementia and MCI is the combination of plaques, tangles, as well as alterations due to vascular disease. In this important book Libon, Lamar, Swenson, and Heilman have assembled an impressive set of contributors to describe the mechanisms, markers, and treatment implications of combined AD and vascular pathology commonly present in dementia and MCI. This endeavor stands to advance our knowledge and shift current research and clinical paradigms that study neurodegenerative illness." -Glenn Smith, Chair of Psychology, University of FloridaIn this book, world-leaders in the area summarize current knowledge on the heterogeneity of Alzheimer's disease, vascular dementia, and mild cognitive impairment, and how these conditions are on a continuum and influence and shape the expression of each other. This book is a must for researchers, clinicians, and others interested in the heterogeneity and overlap of the most common forms of cognitive decline, and will be a standard reference for many years." -Ingmar Skoog, Professor, Institute of Neuroscience and Physiology and Director of the Centre for Ageing and Health, AgeCap, University of Gothenburg, SwedenTable of ContentsPreface Part 1: Epidemiology and Neuropsychology Chapter 1: Vascular risk factors and their relationship to brain aging: Findings from the Framingham Heart Study Chapter 2: Neuropsychological Profiles in Alzheimer's/ Vascular Spectrum Dementia Chapter 3: Neuropsychological Diagnostic Criteria for Mild Cognitive Impairment due to Alzheimer's Disease Chapter 4: Vascular Cognitive Impairment Chapter 5: Decline in Everyday Functioning in MCI and Dementia: A Neuropsychological Perspective Chapter 6: Heterogeneity in Dementia and MCI: Using Statistical Modeling Techniques Chapter 7: Apraxic and Action-Intentional Disorders Associated With Vascular And Degenerative Dementing Diseases Part 2: Neuroimaging Chapter 8: Cerebral small vessel disease and the risk of dementia and cognition decline Chapter 9: Structural MRI in Alzheimer's disease: Are we measuring the right stuff Chapter 10: Advances in Multi-Modal Imaging Across the Spectrum of Normal to Pathological aging: Incorporating Vascular Comorbidities Common to Alzheimer's disease and Vascular Dementia Part 3: Blood-Brain-Barrier and Cardiogenic Mechanisms Chapter 11: The Blood-Brain Barrier in Cognitive Decline and Alzheimer's Disease Chapter 12: Arterial Stiffening and Cerebrovascular Resistance in Cognitive Decline and Alzheimer's Disease Chapter 13: Hemodynamics in Alzheimer's Disease and Vascular Cognitive Impairment & Dementia Part 4: Neuropathological and Neurophysiological Mechanisms Chapter 14: Neuropathology of AD/ VaD Dementia Chapter 15: Potential of blood- and CSF-based biomarkers for AD diagnostics Chapter 16: Unravelling the Role of Mitochondria in Alzheimer's disease: Toward Assembling the Puzzle Part 5: Treatment and Intervention Chapter 17: Dementia and Elective Surgeries: Considerations for Neuropsychologists Chapter 18: Management of Mild Cognitive Impairment

    15 in stock

    £92.00

  • Oxford University Press Functional Neurosurgery Neurosurgery by Example

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £84.15

  • Oxford University Press Spinal Neurosurgery Neurosurgery by Example

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £115.00

  • Oxford University Press Management of Sleep Disorders in Psychiatry

    15 in stock

    Book SynopsisManagement of Sleep Disorders in Psychiatry provides the most comprehensive and evidence-based review of the clinical management of DSM-V based sleep-wake disorders in patients with psychiatric disorders. This book is organized into three sections that focus on the basics of sleep medicine, clinical features and treatment of DSM-V sleep-wake disorders, and evidence-based management of sleep disorders commonly associated with a range of DSM-V based psychiatric disorders. The first section orients the reader to topics such as sleep physiology, neural mechanisms of wakefulness and sleep, circadian rhythms, effects of sleep on cognition, history taking in sleep medicine, and clinical application of technical procedures used in the field of sleep medicine. The second section adopts a unique perspective of using DSM-V classification of sleep-wake disorders to integrate the management of sleep disorders with mainstream clinical psychiatry. This section features a comprehensive chapter on pediatric sleep-wake disorders, a topic of interest to fellows and practicing clinicians specializing in child and adolescent psychiatry. The third section offers the most comprehensive review of comorbidity, shared pathophysiology, and clinical management of sleep disorders within the context of a wide range of DSM-V based psychiatric disorders. This section also highlights important topics such as delirium, neurocognitive disorders, effects of psychotropic medications on sleep, neurological disorders, pain disorders, forensic sleep medicine, and eating disorders. This clinically-oriented resource provides case vignettes and clinical pearls to illustrate the diagnosis and treatment of sleep disorders in the setting of a variety of psychiatric presentations. Additionally, each chapter includes a self-assessment section with multiple-choice questions that helps the reader solidify their clinical skills and prepare for the board and certification examinations for topics pertinent to sleep-wake disorders in psychiatry.Table of ContentsIntroduction to Sleep Medicine 1) Sleep Medicine and Psychiatry: The Inseparable Two 2) Sleep Architecture and Physiology 3) Neurobiology of Sleep and Wakefulness 4) Circadian rhythms 5) Sleep and Cognition 6) Office based Evaluation of Sleep Disordered Patients 7) Clinical Applications of Technical Procedures in Sleep Medicine Sleep-Wake Disorders 8) Insomnia disorder-Pathophysiology 9) Insomnia disorder- Pharmacological treatments 10) Insomnia disorder- Behavioral Treatments 11) Hypersomnolence disorders 12) Parasomnias 13) Circadian rhythm Sleep-Wake disorders 14) Sleep-Related Movement Disorders 15) Breathing-Related Sleep Disorders 16) Pediatric sleep-wake disorders Sleep and Psychiatric disorders 17) Depressive Disorders 18) Bipolar and Related Disorders 19) Anxiety Disorders 20) Trauma and Stressor-Related disorders: 21) Schizophrenia Spectrum and Other Psychotic disorders 22) Substance-Related and Addictive Disorders 23) Neurodevelopmental disorders 24) Delirium 25) Neurocognitive Disorders 26) Neuropsychiatric disorders 27) Pain Disorders 28) Psychotropic medications and Sleep 29) Forensic Sleep Medicine 30) Eating Disorders 31) Future of Sleep Medicine and Psychiatry

    15 in stock

    £74.00

  • Oxford University Press Electric Fields of the Brain

    15 in stock

    Book SynopsisWidely acclaimed when it first published in 1981, this book has been brought up-to-date with this second edition. Topics covered include synaptic sources, electrode placement, choice of reference, volume conduction, power and coherence, projection of scalp potentials to dura surface, dynamic signatures of conscious experience, and neural networks immersed in global fields of synaptic action.Trade ReviewFrom reviews of the first edition:An exceptionally well-written book that will be a useful reference for researchers, clinicians, and educators alike. * Medical Physics *This volume fills an urgent need. It brings together the encephalographer and the physicist and enlightens both. It belongs on the bookshelf of anyone working in the broad and burgeoning field of neuroscience. Reginald G. Bickford is fully justified when he predicts in a brief foreword that the book will become a classic in the field. * Physics Today *Has considerable value in its presentation of clinical, theoretical, and speculative information regarding electrical potentials developed in the brain and their recording... a substantive addition to the library of the physician or scientist. * JAMA *Unique and important for a number of reasons, the most compelling of which is that for the first time a physicist with much practical experience with EEGs has set out to 'tell the whole EEG story'... a fine reference suitable as a textbook for a graduate level course on the EEG in a physiology or engineering department. Clinical neurologists specializing in epilepsy will find chapter six on EEG recording... and chapter seven on EEG analysis most valuable. The practical discussion on the choice of a reference electrode... is itself worth many times the price of the book. * Alan S. Gevins in Epilepsia *Table of ContentsAPPENDICES

    15 in stock

    £152.50

  • Oxford University Press Clock Drawing

    15 in stock

    Book SynopsisWritten by a multi-disciplinary team of experts in neurobehaviour, this concise, well-illustrated book provides long-awaited normative data on clock drawing from ages 20 to 90 years.A practical guide to the quantitative assessment of clock drawing, it also takes a process-oriented approach to qualitative impairment. The authors discuss clock drawing as a neuropsychological test instrument and the rationale for selecting specific time settings, as well as the basis for using different clock conditions.The book contains numerous examples of clocks drawn by patients with cognitive impairment due to dementia, metabolic encephalopathy, traumatic brain injury, disconnection syndrome and focal brain lesions. Insight into changes in clock drawing ability that may represent the earliest markers of cognitive decline in dementia are also presented. This volume will be of interest to clinicians and researchers in neuropsychology, neurology, psychiatry, geriatric medicine, language therapy, and occTrade ReviewThis book is beautifully produced. It is full of excellent examples of clock drawings illustrating the points made in the text. The bibliography is complete and up-to-date. The book is reasonably priced and can be highly recommended to both clinicians and researchers interested in the elderly, and in patients with specific neurological disorders, focal brain lesions, and different forms of dementia. * Hans F. Reichenfeld, Journal of Psychiatry & Neuroscience, Vol. 20, No. 2 1995 *Table of ContentsIntroduction ; 1. Normative study ; 2. Dementia and related disorders ; 3. Well elderly in senior's residence ; 4. Focal brain damage

    15 in stock

    £67.45

  • Oxford University Press Charcot Constructing Neurology

    15 in stock

    Book SynopsisThis book provides the best available account of the life and contributions of Jean-Martin Charcot. It gives a fascinating picture of the man and his milieu, and clearly defines his role in establishing the new medical speciality of clinical neurology.Trade ReviewThe authors have achieved a detailed and balanced synthesis of many points of view derived from all available sources. * Marcus Jacobson, Nature, Vol 381, June 1996 *Table of Contents'n 1Education of a Physician 2: The Struggle for a Career in Paris Medicine 3: The Development of a Career in Neurology 4: Charcot's Major Neurological Interests 5: Charcot and the Artistry of Neurological Practice 6: Hysteria 7: Fame 8: Charcot's Private Life 9: Charcot's Death and Legacy

    15 in stock

    £105.00

  • Oxford University Press, USA Circuits of the Mind

    15 in stock

    Book SynopsisDetails a computational approach to studying the intricate workings of the human brain. Focusing on the brain's enigmatic ability to access quickly a massive store of accumulated information during reasoning processes, the author asks how such feats are possible.Trade ReviewThe book is written in a clear style, with a sufficient number of figures illustrating the algorithms. . .This new insight into complex problems of the brain, as well as the proposed methodology, makes the book highly readable and interesting. * Computing Reviews *The author shows that the proposed neuroidal model supports the cognitive activities he identifies. It provides a good structure to explore the functions of the mind still further. * IIEEE Spectrum *Although there are many books today dealing with a simple neuronal model based on the weighted sum principle, this one rises above these others in providing an explanation of cognitive functions. * Choice *Delivers what its title promises, and more: an engaging, broad, thorough, and often deep, development of undergraduate complex analysis and related areas (non-Euclidean geometry, harmonic functions, etc.) from a geometric point of view. The style is lucid, informal, reader-friendly, and rich with helpful images (e.g., the complex derivative as an "amplitwist"). A truly unusual and notably creative look at a classical subject. * American Mathematical Monthly *Table of Contents1. The Approach ; 2. Biological Constraints ; 3. Computational Laws ; 4. Cognitive Functions ; 5. The Neuroidal Model ; 6. Knowledge Representation ; 7. Unsupervised Memorization ; 8. Supervised Memorization ; 9. Supervised Inductive Learning ; 10. Correlational Learning ; 11. Objects and Relational Expressions ; 12. Systems Questions ; 13. Reasoning ; 14. More Detailed Neural Models ; 15. Afterword

    15 in stock

    £45.59

  • Oxford University Press, USA Neurological Eponyms

    15 in stock

    Book SynopsisNeurology abounds with eponyms. This book brings together 55 eponyms related to neurological examination, neuroanatomy and neurological diseases. For each it provides a short biography, a discussion of the original publication, and a discussion of the evolution and significance of the eponym.Trade Review"...a beautiful book describing the origin and clinical neurosciences...The editors' goal for this book was education and entertainment. They have succeeded quite admirably."--New England Journal of Medicine Noted in Nature "This book opens a valuable window on interesting people...Neurologists, neurosurgeons, neuroscientists, internists, and other generalists with an interest in the history of neurology would probably enjoy it."--JAMA2001 "The editors' goal for this book was education and entertainment. They have succeeded quite admirably."--New England Journal of MedicineAugust 2001 "...both educational and entertaining...By any account, this book is a success and can be warmly recommended."--Ian McDonald in BRAINTable of ContentsPART I STRUCTURES AND PROCESSES; PART II SYMPTOMS AND SIGNS; PART III REFLEXES AND OTHER TESTS; PART IV SYNDROMES; PART V DISEASES AND DEFECTS

    15 in stock

    £82.65

  • Oxford University Press, USA Stimulant Drugs and ADHD Basic and Clinical Neuroscience

    15 in stock

    Book SynopsisStimulant drugs are widely used in the treatment of ADHD in children and adults, yet their mechanism of action have been poorly understood. This volume integrates advances in the basic and clinical neurosciences in order to shed light on this question.Trade Review"This book is an ambitious, even courageous, attempt to pull together evidence from the basic and clinical neurosciences that may ultimately help explain how stimulant drugs act to reduce the behavioral and cognitive symptoms associated with attention-deficit-hyperactivity disorder (ADHD)." --Contemporary Psychology "This book is an ambitious, even courageous, attempt to pull together evidence from the basic and clinical neurosciences that may ultimately help explain how stimulant drugs act to reduce the behavioral and cognitive symptoms associated with attention-deficit-hyperactivity disorder (ADHD)." --Contemporary Psychology "...a volume that will interest almost anyone who works with attention deficit hyperactivity disorder (ADHD) in either clinics or research programs"--The Journal of Nervous and Mental Disease "...a timely addition to the ever growing literature on the most controversial of pharmacotherapies for children and adolescents...most of the chapters are engaging....The clinical chapters by Mary Solanto(on the clinical features of ADHD), Laurence Greenhill(on the clinical effects of stimulant medication), and the final, challenging chapet by Solanto, Amy Arnsten, and Xavier Castellanos are outstanding."--The Lancet, 2001 "This slender volume is an excellent collection of reviews on ADHD in the context of modern psychopharmacology and neuroscience....The quality of all the chapters is consistently of a very high standard, each text a gem on its own. They are concisely written and densely packed with relevant information. The materials are accessible, despite being technical in nature...a superb set of essays....Overall, this is--and I believe will remain for some time--a benchmark publication, relevant to any clinician who prescribes ADHD psychopharmacological treatment, and to investigators in ADHD research from medical or neuroscience backgrounds alike."--Journal of Child Psychology and PsychiatryTable of ContentsPART I: PHENOMENOLOGY; PART II: BASIC NEUROSCIENCE; PART III: CLINICAL NEUROSCIENCE; PART IV: INTEGRATION

    15 in stock

    £112.50

  • Oxford University Press, USA Neurology of Cognitive and Behavioral Disorders

    15 in stock

    Book SynopsisThis reference text provides an insightful and unified synthesis of cognitive neuroscience and behavioral neurology. The strong clinical emphasis and outstanding illustrations will provide neurologists, psychiatrists, neuropsychologists, and psychologists with a solid foundation to the major neurobehavioral syndromes. With backgrounds in behavioural neurology, functional imaging and cognitive neuroscience, the two authors are in an ideal position to cover the anatomy, genetics, physiology, and cognitive neuroscience underlying these disorders. Their emphasis on therapy makes the book a must read for anyone who cares for patients with cognitive and behavioural disorders.Trade Review. . . part of the highly regarded Contemporary Neurology Series, and it carries on the tradition of excellence neurologists have come to expect of these volumes . . . The writing style is concise, clear, readable. Clinical vignettes and example cases, drawn both from the authors' experience and the published literature, reinforce important concepts . . . Devinsky and D'Esposito have broken new ground with a fresh approach to the neurology of cognition and behavior . . . * Neurology *The latest in the "Contemporary Neurology Series", Neurology of Cognitive and Behavioural Disorders, is a comprehensive, authoritative, and practical tome for clinicians, as a stand-alone reference and as an entertaining way of using the time allocated for those outpatient no-shows . . . This book should appeal to a wide range of neuroscience subspecialists, and comes with a strong recommendation to clinical neurologists from this reviewer. * The Lancet Neurology *Table of Contents1. Neuroanatomy and Assessment of Cognitive-Behavioural Function ; 2. Functional Neuroimaging of Cognition ; 3. The Right Hemisphere, Interhemispheric Communication, and Consciousness ; 4. Attention and Attentional Disorders ; 5. Perception and Perceptual Disorders ; 6. Language, Aphasia, and Other Speech Disorders ; 7. Motor System and Behaviour ; 8. Memory and Memory Disorders ; 9. Executive Function and the Frontal Lobes ; 10. Emotion and the Limbic System ; 11. Therapy for Cognitive and Neurobehavioral Disorders

    15 in stock

    £145.00

  • Oxford University Press Matter of Mind

    15 in stock

    Book SynopsisMost of what has been learned about how the brain mediates behaviour comes from experiments of nature where a stroke or other damage to the brain produces changes in a person''s behaviour. In Matter of Mind, one of the leading figures in behavioural and cognitive neurology uses patient vignettes and other examples from his rich professional life to show just how much knowledge about brain functions such as reading, writing, language, control of emotions, skilled movement, perception, attention, and motiviation has been gained from the study of patients with diseases of or damage to the brain. No knowledge of neurology or neuroscience is required to understand the book, which is intended for neurological patients and their families. It will also be of interest to professionals who study the brain or treat patients with brain damage including neuropsychologists, neurologists, neuroscientists, psychologists, speech pathologists, occupational and physical therapists, and their students andTrade ReviewFor those fascinated by neurobehavioural syndromes and how the disordered mind can be understood from intensive observation and experimental deduction . . . [this book] offers an important perspective . . . an adventurous romp through the modern history of behavioural neurology . . . fosters an appreciation for the intricacies and subtlety of brain-behaviour relationships. The information is presented in a way a layperson can understand, and a neurologist, young or mature, can relish. * Neurology Today *This is a book intended for general public readership. It is surely going to be enjoyed by readers with interest in how the brain works and, specifically, in the relationship between brain and mind, even if they do not have a specific knowledge in neurology. The book is timely, trying to fill up some of the remaining gaps in the ever-growing scientific study of behaviour, emotions, cognition, and other similar human brain mediated functions . . . It is well written in an easy-to-read conversational tone that makes the very complex mind matters understandable, and attractive, to the non-specialized reader. * Clinical Neurophysiology, 114 *Table of Contents1: Introduction 2: Language-Cognition Speech - Reading - Writing 3: Emotion Emotional Communication - Emotional Experience 4: Attention 5: Self-Awareness 6: Memory 7: Motor Skills 8: Sensory Perception 9: Conation-Intention

    15 in stock

    £52.25

  • Oxford University Press, USA The Brain Takes Shape An Early History

    15 in stock

    Book SynopsisTells the story of how long-standing notions about the body as dominated by spirit-like humors were transformed into scientific descriptions of its solid tissues. This book shows how debates over investigative methods and models of body order influence biomedicine and the broader culture.Trade ReviewAdvance Praise for The Brain Takes Shape:Scholars often pay lip service to the important roles of theological and philosophical concepts in the making of modern science and medicine. Robert Martensen has taken the platitude seriously, and his book powerfully demonstrates how our modern beliefs about mind and body were first elaborated in the seventeenth century, when philosophy, theology and science were intertwined. The result is a cultural history of biomedicine at its very best. * W.F. Bynum, Wellcome Trust Centre for the History of Medicine, University College London *Table of ContentsSelected events and historical actors ; 1. Bodies, words, and images ; 2. Matter, spirit, and the heart ; 3. The human mind and "Gland H": Cartesian models of mind, brain, and nerves ; 4. When the brain came out of the skull ; 5. Body of witnesses ; 6. Toward a new physiology of human conduct ; 7. The transformation of Eve ; 8. Mind without brain: John Locke, Thomas Syndenham, and the constitutional body of the British enlightenment ; 9. On the persistence of the cerebral body and its alternatives

    15 in stock

    £64.60

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