Neurology and clinical neurophysiology Books

Book SynopsisBridges the gap between AI and neuroscience by telling the story of how the brain came to be.''I found this book amazing'' Daniel Kahneman, Winner of the Nobel Prize in Economics and bestselling author of Thinking Fast & SlowThe entirety of the human brain's 4-billion-year story can be summarised as the culmination of five evolutionary breakthroughs, starting from the very first brains, all the way to the modern human brains. Each breakthrough emerged from new sets of brain modifications, and equipped animals with a new suite of intellectual faculties.These five breakthroughs are the organising map to this book, and they make up our itinerary for our adventure back in time. Each breakthrough also has fascinating corollaries to breakthroughs in AI. Indeed, there will be plenty of such surprises along the way. For instance: the innovation that enabled AI to beat humans in the game of Go temporal difference reinforcement learning was an innovation discovered by our fish ancestors over 500 million years ago. The solutions to many of the current mysteries in AI such as common sense' can be found in the tiny brain of a mouse. Where do emotions come from? Research suggests that they may have arisen simply as a solution to navigation in ancient worm brains. Unravelling this evolutionary story will reveal the hidden features of human intelligence and with them, just how your mind came to be.

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Book Synopsis''An inspired road map for living with a distractible brain... If you or your child suffer from ADHD, this book should be on your shelf. It will give you courage and hope''. Michael Thompson, PhD, New York Times bestselling co-author of Raising CainWorld-renowned authors Dr Edward M. Hallowell and Dr John J. Ratey literally ''wrote the book'' on ADD/ADHD more than two decades ago. Their bestseller, Driven to Distraction, largely introduced this diagnosis to the public and sold more than a million copies along the way.Now, most people have heard of ADHD and know someone who may have it. But lost in the discussion of both childhood and adult diagnosis of ADHD is the potential upside: many hugely successful entrepreneurs and highly creative people attribute their achievements to ADHD. Also unknown to most are the recent research developments, including innovations that give a clearer understanding of the ADHD brain in action. In ADHTrade ReviewHallowell writes with clarity and humanity... [ADHD 2.0] is a message of hope... a remarkably clear, personable, digestible and useful book. * Dr Lloyd Sederer, 'Psychology Today' *Beautifully written, ADHD 2.0 is an inspired road map for living with a distractible brain. Two psychiatrists who have ADHD themselves combine the most recent brain science with humor, stories, and deep wisdom about how to manage your fluctuating attention. If you or your child suffer from ADHD, this book should be on your shelf. It will give you courage and hope. * Michael Thompson, Ph.D., 'New York Times' bestselling co-author of 'Raising Cain' *Infinitely validating, effortlessly funny, and staggeringly insightful . . . This book will save lives. * Jessica McCabe, creator/host of 'How to ADHD' *I love the optimism and hope this timely book offers.. . . . Drs. Hallowell and Ratey draw upon the latest neuroscience as well as other key research fields to offer a comprehensive and helpful approach to living fully and happily with ADHD. . . . Highly recommended. * Peter S. Jensen, M.D., founder, The REACH Institute *As both a clinician and someone with ADHD, I found this book to be a reassuring masterpiece. Drs. Hallowell and Ratey combine evidence-based practice and research to help those with ADHD live a fulfilled and happy life. I will recommend it to my patients. * —Kristin Seymour, M.S.N., R.N., ADHD coach *With knowledge and empathy, Drs. Hallowell and Ratey have written a book that draws on the latest scientific advances and their decades of clinical experience. Most important, ADHD 2.0 provides hope; it is a must-read for anyone who has or loves a person with this very common condition. * Harold S. Koplewicz, M.D., president and medical director, Child Mind Institute, and author of 'The Scaffold Effect' *This information-packed guide is a must-have for anyone dealing with ADHD. * —Publishers Weekly *

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Book Synopsis**THE MILLION COPY BESTSELLER** 'Rattling. Heartbreaking. Beautiful.' Atul Gawande, bestselling author of Being Mortal What makes life worth living in the face of death? At the age of thirty-six, on the verge of completing a decade's training as a neurosurgeon, Paul Kalanithi was diagnosed with inoperable lung cancer. One day he was a doctor treating the dying, the next he was a patient struggling to live. When Breath Becomes Air chronicles Kalanithi's transformation from a medical student asking what makes a virtuous and meaningful life into a neurosurgeon working in the core of human identity - the brain - and finally into a patient and a new father. Paul Kalanithi died while working on this profoundly moving book, yet his words live on as a guide to us all. When Breath Becomes Air is a life-affirming reflection on facing our mortality and on the relationship between doctor and patient, from a gifted writer who became both. 'A vital book about dying. Awe-inspiring and exquisite. Obligatory reading for the living' Nigella LawsonTrade ReviewA vital book about dying. Awe-inspiring and exquisite. Obligatory reading for the living. -- Nigella LawsonRattling. Heartbreaking. Beautiful. -- Atul Gawande, author of BEING MORTALA great, indelible book ... as intimate and illuminating as Atul Gawande’s “Being Mortal,” to cite only one recent example of a doctor’s book that has had exceptionally wide appeal ... I guarantee that finishing this book and then forgetting about it is simply not an option ... gripping from the start ... None of it is maudlin. Nothing is exaggerated. As he wrote to a friend: “It’s just tragic enough and just imaginable enough.” And just important enough to be unmissable. * New York Times *Powerful and poignant. * The Sunday Times *Less a memoir than a reflection on life and purpose… A vital book. * The Economist *Powerful and poignant… Elegantly written posthumous memoir… Should be compulsory for anyone who intends to be a doctor… A profound reflection on the meaning of life. -- Daisy Goodwin * Sunday Times *A stark, fascinating, well-written and heroic memoir. -- Stefanie Marsh * The Times *The power of this book lies in its eloquent insistence that we are all confronting our mortality every day, whether we know it or not. The real question we face, Kalanithi writes, is not how long, but rather how, we will live – and the answer does not appear in any medical textbook. -- Alice Okeeffe * Guardian *Exceptional. -- Katie Law * Evening Standard *When I came to the end of the last flawless paragraph of When Breath Becomes Air, all I could do was turn to the first page and read the whole thing again. Searingly intelligent, beautifully written, and beyond brave, I haven't been so marked by a book in years. -- Gabriel Weston, author of DIRECT REDA remarkable book… Kalanithi writes very well, in a plain and matter-of-fact way, without a trace of self-pity, and you are immediately gripped and carried along… [He] was clearly a deeply thoughtful and compassionate man, and his death is a great loss to medicine, but at least he has left this remarkable book behind. -- Dr Henry Marsh * Observer *A meditation on what makes a life worth living. * Guardian *It turns out not really to be about dying at all but about life and how to live it — though the closeness of death gives it an urgency and economy… When Breath Becomes Air is a Renaissance book from a Renaissance man. It is a work of philosophy and morality, a reconciliation of science and religion. There is even plot and excitement… It was only with the restrained, elegant epilogue written by his wife Lucy Kalanithi that I found myself weeping helplessly… When Breath Becomes Air tells us what means to live a good life, by giving us a glimpse into an exceptional one. -- Lucy Kellaway * Financial Times *A powerful and compelling read. * The Economist, Book of the Year *An astonishingly affecting memoir and eloquent examination of what it is to be human and confront your own mortality… This is a remarkable book by a man who was driven by his passion for his life, his loves and his career. His death is undoubtedly a tragedy but in writing this memoir he has guaranteed that his voice and the important story it tells will resonate for years to come. -- Mernie Gilmore * Daily Express *As thought-provoking as it was moving. The sheer exuberance of Kalnithi’s intellectual curiosity shone through in his writing. -- Katie Law * Evening Standard, Book of the Year *To the venerable canon of doctors who could write (from Chekhov to Oliver Sacks and Atul Gawande), another name can be added: that of Paul Kalanithi… Brilliantly written. -- Louise Carpenter * Sunday Telegraph *Paul Kalanithi’s memoir, When Breath Becomes Air… split my head open with its beauty. Truly. Madly. Deeply. -- Cheryl Strayed, author of WILDThanks to When Breath Becomes Air, those of us who never met Paul Kalanithi will both mourn his death and benefit from his life. This one of a handful of books I consider to be a universal donor - I would recommend it to anyone, everyone. -- Ann Patchett, author of BEL CANTOA remarkable book about what it means to live…a tour de force…The book will be compared inevitably to Sacks’ work and also to the iconic book that Joan Didion wrote about grief, The Year of Magical Thinking. And like that book, it’s destined to become an elegiac classic on the subject of mortality. But it’s a different feeling from Didion’s gorgeous, melancholy fog of war. When Breath Becomes Air is electrically alive in its anticipation of death. -- Lisa Chase * Elle *

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Book SynopsisFrom the man dubbed the ‘Sleep Whisperer’ comes a brand-new approach to fixing your sleep, once and for all. Challenging the reader to take control and to stop hiding behind excuses for a bad night’s sleep, neurologist W. Chris Winter explains the basic, often-counterintuitive rules of sleep science. Dr Winter explores revolutionary findings, including surprising solutions for insomnia and other sleep disturbances, empowering readers to stop taking sleeping pills and enjoy the best sleep of their lives. Written in a clear and entertaining way, The Sleep Solution contains tips, tricks, exercises, and illustrations throughout. Dr Winter is an international expert on sleep and has helped thousands of patients — including professional athletes — rest better at night. Now, he's ready to help you.Trade Review‘I call Dr. Winter a sleep whisperer. Through his work with top athletes, he’s found an amazingly effective way to show that sleep can be the ultimate performance enhancer — in sports, at work, and in every aspect of our lives.’ -- Arianna Huffington‘[I]rreverent but still rooted in clinical science … [Winter’s] no-nonsense advice can be quickly summoned at 3.07am when the temptation to check Facebook or raid the biscuit tin can feel overwhelming.’ * Evening Standard *‘Until I met Chris Winter, I slept like a baby: I woke every two hours and cried. And then Dr. Winter … helped me. He was my sleep solution; this book will be yours.’ * Peter Moore, co-author The Eight-Hour Diet *‘[The Sleep Solution] is already being hailed as a ‘solution’ to insomnia. It's a no-nonsense, colloquial approach to sleep difficulties that aims to change the narrative around sleep in order to make it more manageable.’ -- Jess Commons * Refinery29 *‘Chris is world class in his field; he is incredibly pragmatic in his application of medicine to real world, high-performance settings.’ -- Mark Simpson, LA Clippers Director of Performance and former Head of Strength and Conditioning for the British Cycling Team‘Dr. Winter has spent his career bringing attention to the benefits of sleep and for the first time, this book brings it all together. He has written an important resource for athletic trainers and professional athletes alike. His professional experiences and research has assisted with bringing to light the impact sleep has on our athletes within their sport.’ -- Ben Potenziano, Assistant Athletic Trainer, Pittsburgh Pirates‘Dr. Winter's ‘personal touch’ [is] his … touch of humor and true caring about improving … lives through ‘healthy sleep.’’ -- Herm Schneider, Head Athletic Trainer Chicago White Sox‘Dr. Chris Winter’s new work, The Sleep Solution, is a jewel of a book for anyone who has struggled with sleep issues.’ -- Ron Adams, veteran coach of the Golden State Warriors‘Dr. Winter is our go-to sleep specialist. In The Sleep Solution, you will find much of what he has shared with our athletes as he has helped us navigate the rigorous NBA schedule.’ -- Donald S. Strack, DPT, ATC Director of Medical Services Oklahoma City Thunder‘In the baseball industry, the travel, change in time zones and just sleeping in a different bed is not easy. I have leaned on Dr. Winter many times. Thank you Chris.’ -- Ron Porterfield, Athletic Trainer Tampa Bay Rays

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Book SynopsisWinner of the 2015 Samuel Johnson Prize for Non-FictionShortlisted for the Wellcome Book PrizeA Sunday Times and New York Times bestsellerForeword by Oliver SacksWhat is autism: a devastating developmental condition, a lifelong disability, or a naturally occurring form of cognitive difference akin to certain forms of genius? In truth, it is all of these things and more - and the future of our society depends on our understanding it. Following on from his groundbreaking article 'The Geek Syndrome', Wired reporter Steve Silberman unearths the secret history of autism, long suppressed by the same clinicians who became famous for discovering it, and finds surprising answers to the crucial question of why the number of diagnoses has soared in recent years.Going back to the earliest autism research and chronicling the brave and lonely journey of autistic people and their families through the decades, Silberman provides long-sought solutions to the autism puzzle while casting light on the growing movement of 'neurodiversity' and mapping out a path towards a more humane world for people with learning differences.Trade ReviewStunning... Highly original... Outstanding. * Spectator, Best Books of 2015 *A sprawling and fascinating dissection of the role autism has played in shaping human history. * Daily Telegraph, Best Books of 2015 *Whatever the future of autism...Mr Silberman has surely written the definitive book about its past. * The Economist, Best Books of 2015 *A rich amalgam of social history and contemporary reportage. * Financial Times, Best Books of 2015 *[An] epic history of autism. * Sunday Telegraph *Ambitious, meticulous and largehearted... Beautifully told, humanizing, important. * New York Times, Best Books of 2015 *Silberman's phenomenal book goes a long way to uncovering some of the myths about this particular "tribe" and is all for recognising their incredible talents and contributions to society. * The Sun *Brilliant and sparklingly humane. * Guardian, Best Books of 2015 *NeuroTribes is deeply felt. * The Times, Best Books of 2015 *Powerful, authoritative... This is a significant book. * The Sunday Times, Best Books of 2015 *It's not just a book about autism but a journey through the history of cognitive difference and our evolving attitudes towards it. * Metro, Best Books of 2015 *Silberman sheds a sage and humane light on a much-misrepresented aspect of human nature. * Independent, Best Books of the Year *Steve Silberman explores in fascinating, near-encyclopaedic depth how autism has evolved. It's a gripping narrative written with journalistic verve. * Observer *Silberman is a skilled storyteller... [He] researches with scientific rigour... A powerful voice: NeuroTribes offers keen insight. * New Statesman *Silberman's sweeping history is always sensitive and builds a persuasive argument that the ability to think differently is useful, necessary even, for the success of the modern world. * New Scientist *This excellent book is the result of fifteen years of work. As the late Oliver Sacks put it, "I know of no one else who has spent so much time simply listening, trying to understand what it is like to be autistic." -- William Leith * Evening Standard, Best Books of 2015 *A tome that beautifully, compassionately and brutally traces the history of autism from centuries past into the present and possible future... Everyone needs to read this book. Everyone. * Forbes *NeuroTribes is remarkable. Silberman has done something unique: he's taken the dense and detailed history of autism and turned the story into a genuine page-turner. The book is sure to stir considerable discussion. -- John Elder Robison, author of Look Me in the EyeA lively, readable book... To read NeuroTribes is to realize how much autistic people have enriched the scope of human knowledge and diversity, and how impoverished the world would be without them. * San Francisco Chronicle, Best Books of 2015 *A comprehensive history of the science and culture surrounding autism studies... An essential resource. * Nature magazine *Breathtaking... As emotionally resonant as any [book] this year. * The Boston Globe, Best Books of 2015 *It's a readable, engaging story. But it's also a serious political and sociological critique, couched in a 500-page-long piece of original historical scholarship. * Salon *Nothing short of a revelation... Sweeping and lovingly detailed. * Parent.co *The monks who inscribed beautiful manuscripts during the Middle Ages, Cavendish an 18th century scientist who explained electricity, and many of the geeks in Silicon Valley are all on the autism spectrum. Silberman reviews the history of autism treatments from horrible blaming of parents to the modern positive neurodiversity movement. Essential reading for anyone interested in psychology. -- Temple Grandin, author of Thinking in Pictures and The Autistic BrainIt is a beautifully written and thoughtfully crafted book, a historical tour of autism, richly populated with fascinating and engaging characters, and a rallying call to respect difference. * Science magazine *Epic and often shocking... Everyone with an interest in the history of science and medicine - how it has failed us, surprised us and benefited us - should read this book. * Chicago Tribune *The best book you can read to understand autism. * Gizmodo *This is perhaps the most significant history of the discovery, changing conception and public reaction to autism we will see in a generation. * TASH.org *A well-researched, readable report on the treatment of autism that explores its history and proposes significant changes for its future... In the foreword, Oliver Sacks writes that this "sweeping and penetrating history...is fascinating reading" that "will change how you think of autism." No argument with that assessment. * Kirkus Reviews *Stunning...a remarkable narrative...one of the most fascinating accounts of autism I have ever read. -- Simon Baron-Cohen * The Lancet *Essential reading if you have an autistic child; highly recommended for anyone with an interest in the workings of the mind. * The Tablet *The story of autism reads more like a novel, with a vivid cast of characters, power struggles, obsessions - and heroic efforts of insight. * The Psychologist *

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Book Synopsis____________________________A moving celebration of what Bill Hayes calls ''the evanescent, the eavesdropped, the unexpected'' of life in New York City, and an intimate glimpse of his relationship with the late Oliver Sacks.____________________________''A beautiful memoir in which Oliver Sacks comes wonderfully to life ... Exquisitely wrought, heartrending and joyous'' - Joyce Carol Oates''A loving tribute to Sacks and to New York ... Read just 50 pages, and you'll see easily enough how Hayes is Sacks's logical complement'' - Jennifer Senior, New York Times____________________________Bill Hayes came to New York in 2009 with a one-way ticket and only the vaguest idea of how he would get by. But, at forty-eight years old, having spent decades in San Francisco, he craved change. Grieving over the death of his partner, he quickly discovered the profound consolations of the city's incessant rhythms, the sight of the Empire State Building agaiTrade ReviewA loving tribute to Sacks and to New York ... Read just 50 pages, and you’ll see easily enough how Hayes is Sacks’s logical complement. Though possessed of different temperaments, both are alive to difference, variety, the possibilities of our rangy humanity; both are avid chroniclers of our species -- Jennifer Senior * New York Times *A beautiful memoir in which Oliver Sacks comes wonderfully to life ... Exquisitely wrought, heartrending and joyous -- Joyce Carol OatesLike New York, the city he celebrates so poignantly in this book, Bill Hayes mixes 'memory with desire' to create a heartbreakingly gorgeous story of love, loss, and renewal -- Azar Nafisi, author of READING LOLITA IN TEHRANRemarkably poignant. Readers will find themselves wishing the two men had more time, but as Hayes makes clear, they wasted none of the time they had * Publishers Weekly *Written in heightened states of feeling that infuse every detail with meaning and transient beauty * Shelf Awareness *A unique and exuberant celebration of life and love * Kirkus Reviews *Bill Hayes has an unusual set of skills ... He is part science writer, part memoirist, part culture explainer * The New York Times *Like Patti Smith's haunting M Train, Hayes' book weaves seemingly disparate threads of memory into a kind of sanctuary – a secret place where one can shake off the treasured relics of past lives and prepare to be reborn anew * San Francisco Chronicle *Hayes captures both the frenetic, exhilarating pace of New York City as well as the whimsy, fun and romance of the years he spent with Sacks * New York Post *Insomniac City is resoundingly about life – about being wide awake to possibility, to the beauty of every fleeting moment. * Oprah.com *Buy a box of tissues and pray for snow: This is the perfect weekend February read, and will have you alternately bawling and giddily clapping your hands for the lovers that may not have had the time they deserved, but certainly made the best with the time that they had * Newsweek, 'The Best New Book Releases' *As eloquent in its silences and visuals as it is in its telling of the secrets of the heart. . . . The brilliance of Insomniac City is that almost Tolstoy-an directness and concretion of observation, both down-to-earth and downright visionary * Bay Area Reporter *Poetic and profound ... What emerges from this dual love letter is a lyrical reminder that happiness and heartache are inseparably entwined ... Insomniac City is an ineffably splendid read in its entirety, a mighty packet of pure aliveness. * Brainpickings *This beguiling brew of fascinating scientific facts and illuminating, poignant anecdotes makes Five Quarts something like blood itself: vital and pulsing with energy * Entertainment Weekly *That life permeates every page of Insomniac City, a dual love story of a powerful relationship that will shortly end but, also, of a city that is constantly reinventing itself * Counterpunch *

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Book SynopsisDr Louanne Brizendine is Clinical Professor of Psychiatry and director of the Women's Mood and Hormone Clinic at the University of California. She has more than three decades of experience as a physician, psychiatrist, psychopharmacologist and has studied the female brain for the past 20 years. She lives in San Francisco with her husband and son.Trade ReviewFinally, a satisfying answer to Freud's question: what does a woman want? Louann Brizendine has done a great favour for every man who wants to understand the puzzling women in his life. A breezy and enlightening guide to women - and a must-read for men -- Daniel Goleman, author of Emotional IntelligenceSassy, witty, reassuring and great fun. All women and the men who love them, should read this book -- Christiane Northrup, author of Women's Bodies, Women's WisdomTimely, insightful, readable and an altogether magnificent book -- Sarah Hardy, author of Mother NatureAn eye-opening account of the biological foundations of human behaviour. Destined to become a classic... -- Marilyn Yalom, author of A History of the WifeRanging from sex to breast-feeding, fights to teenage girls, Brizendine communicates in a fresh, engaging style, explaining the structure of the brain, which determines women's thoughts, values and communication skills. A fantastic guide from a heavyweight academic. * Good Book Guide *

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Book SynopsisA work on attention deficit disorder in adults, this title explores the science, diagnostic process, and treatment options, and provides both moral support and practical tips for reducing chaos and disorganization, improving memory, and forging better relationships at home and work.

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Book Synopsis'Science writing at its absolute best' Guy Claxton, author of Intelligence in the FleshInteroception is one of our most important - and most mysterious - senses. It's how our bodies tell our brains what we're feeling - when we're hungry, when we're cold, how we should respond to stress and panic.In Inner Sense, Caroline Williams uncovers a field that's poised to revolutionise health, and explores groundbreaking new techniques that can improve our mental and physical wellbeing. She meets brain scientists mapping the nervous system, neurodivergent researchers working to hone their interoception skills and health practitioners investigating how this inner sense can aid mindfulness, and even disordered eating.Combining science, medicine, mindfulness and physical therapy, Inner Sense is the first book to bring this exciting new field of medicine to a general readership.

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Book SynopsisFocusing on stepwise development of concepts, pattern recognition and integration with clinical practice, Reading EEGs: A Practical Approach, 2nd Edition, is an easy-to-use, readable guide to learning EEG for neurology residents, clinical neurophysiology fellows, and electroneurodiagnostic students and technologists. The emphasis on waveform recognition enables readers to interpret EEG findings accurately and place them in clinical context. The new landscape format accommodates larger high-quality images for improved study, and the distinctive question-and-answer format is highly effective for review at all levels of training. Presents concepts of pattern recognition in a sequential, logical fashion based on appearance rather than disease process. Covers simple, intermediate, and advanced topics in EEG, epilepsy, and neurophysiology. Includes several new chapters, including: The pathophysiology of epileptiform activity covering the neuroscience of seizure generation and the origins of pathological waveforms, Separate chapters on subdural and stereotactic EEG recording, Updated discussions of seizure semiology based on new terminology, New chapters on epilepsy genetics and non-epileptic events. Features expanded coverage of high density EEG, seizure detection methods, magnetoencephalography and intraoperative monitoring. Enrich Your Ebook Reading Experience Read directly on your preferred device(s),such as computer, tablet, or smartphone. Easily convert to audiobook,powering your content with natural language text-to-speech.

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Book SynopsisOur brains were designed for tribal life, for getting along with a select group of others (Us), and for fighting off everyone else (Them). But modern life has thrust the world's tribes into a shared space, creating conflicts of interest and clashes of values, along with unprecedented opportunities. As the world shrinks, the moral lines that divide us become more salient and more puzzling. We fight over everything from tax codes to gay marriage to global warming, and we wonder where, if at all, we can find our common ground.A grand synthesis of neuroscience, psychology, and philosophy, Moral Tribes reveals the underlying causes of modern conflict and lights a way forward. Our emotions make us social animals, turning Me into Us. But they also make us tribal animals, turning Us against Them. Our tribal emotions make us fight, sometimes with bombs, sometimes with words, and often with life-and-death stakes. Drawing inspiration from moral philosophy and cutting-edge science, Moral Tribes shows when we should trust our instincts, when we should reason, and how the right kind of reasoning can move us forward.Joshua Greene is the director of Harvard University's Moral Cognition Lab, a pioneering scientist, a philosopher, and an acclaimed teacher. The great challenge of Moral Tribes is this: How can we get along with Them when what they want feels so wrong? Finally, Greene offers a surprisingly simple set of maxims for navigating the modern moral terrain, a practical road map for solving problems and living better lives.Trade ReviewThis is an important synthesising work of great depth and breadth. Time and again Greene nails what is centrally important -- Julian Baggini * Financial Times *With wit and clarity, Greene steers the reader through a mountain of evidence... A challenging and fascinating read. * Independent on Sunday *More than a decade in the making, Moral Tribes is a masterpiece - a landmark work brimming with originality and insight that also happens to be wickedly fun to read. The only disappointing thing about this book is that it ends. -- Daniel GilbertBrilliant and enlightening... This book should be widely read and discussed. -- Peter SingerA decade ago, the wunderkind Joshua Greene helped start the field of moral neuroscience, producing dazzling research findings. In this equally dazzling book, Greene shows that he is also one of the field's premier synthesists. -- Robert SapolskyThere is a wealth of books in this area, but Greene has something new to bring to the debate... Thoughtful and thought-provoking * Times Literary Supplement *

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Book SynopsisTable of ContentsIntroduction 1 Part 1: Introducing the Nervous System 5 Chapter 1: A Quick Trip through the Nervous System 7 Chapter 2: All about the Brain and Spinal Cord 23 Chapter 3: Understanding How Neurons Work 51 Part 2: Translating the Internal and External Worlds through Your Senses 69 Chapter 4: Feeling Your Way: The Skin Senses 71 Chapter 5: Looking at Vision 87 Chapter 6: Sounding Off: The Auditory System 109 Chapter 7: Odors and Taste 127 Part 3: Moving Right Along: Motor Systems 143 Chapter 8: Movement Basics 145 Chapter 9: Coordinating Things More: The Spinal Cord and Pathways 159 Chapter 10: Planning and Executing Actions 173 Chapter 11: Unconscious Actions with Big Implications 191 Part 4: Intelligence: The Thinking Brain and Consciousness 211 Chapter 12: Understanding Intelligence, Consciousness, and Emotions 213 Chapter 13: How the Brain Processes Thoughts 239 Chapter 14: The Executive Brain 259 Chapter 15: Learning and Memory 275 Chapter 16: Developing and Modifying Brain Circuits: Plasticity 299 Chapter 17: Neural Dysfunctions, Mental Illness, and Drugs That Affect the Brain 325 Part 5: The Part of Tens 339 Chapter 18: Ten (or So) Crucial Brain Structures 341 Chapter 19: Ten Tricks of Neurons That Make Them Do What They Do 349 Chapter 20: Ten Promising Treatments for the Future 357 Glossary 367 Index 383

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Book SynopsisBridges the gap between AI and neuroscience by telling the story of how the brain came to be.''I found this book amazing'' Daniel Kahneman, Winner of the Nobel Prize in Economics and bestselling author of Thinking Fast & SlowThe entirety of the human brain's 4-billion-year story can be summarised as the culmination of five evolutionary breakthroughs, starting from the very first brains, all the way to the modern human brains. Each breakthrough emerged from new sets of brain modifications, and equipped animals with a new suite of intellectual faculties.These five breakthroughs are the organising map to this book, and they make up our itinerary for our adventure back in time. Each breakthrough also has fascinating corollaries to breakthroughs in AI. Indeed, there will be plenty of such surprises along the way. For instance: the innovation that enabled AI to beat humans in the game of Go temporal difference reinforcement learning was an innovation discovered by our fish ancestors over 500 million years ago. The solutions to many of the current mysteries in AI such as common sense' can be found in the tiny brain of a mouse. Where do emotions come from? Research suggests that they may have arisen simply as a solution to navigation in ancient worm brains. Unravelling this evolutionary story will reveal the hidden features of human intelligence and with them, just how your mind came to be.Trade Review‘Max Bennett published two scientific papers on brain evolution that blew me away. Now he has turned these into a fabulous book, A Brief History of Intelligence. His friendly writing style, clear jargon-free prose, and well of information make this book a winner.’ Joseph LeDoux, Henry and Lucy Moses Professor of Neural Science & Psychology at NYU, bestselling author of Anxious and A Deep History of Ourselves ‘With a truly mindboggling scope, A Brief History of Intelligence integrates the most relevant scientific knowledge to paint the big picture of how the human mind emerged. The red line through this book never gets blurred by unnecessary detail or jargoned language. It makes for exciting reading for virtually everybody, laypersons and experts alike.’ Kurt Kotrschal, Professor at Department of Behavioral Biology at University of Vienna, author of Dog & Human: The secret of our soul mates ‘If you’re in the least bit curious about that 3-pound grey blob between your ears, read this book. Max Bennett’s entertaining and enlightening natural history of brains is a tour de force–as refreshing as it is entertaining. It made my brain happy.’ Jonathan Balcombe, bestselling author of Super Fly, and the New York Times bestseller What a Fish Knows ‘Max Bennett gives a lively account of how brains evolved, and how the brain works today. A Brief History of Intelligence is engaging, comprehensive, and brimming with novel insights.’ Kent Berridge, James Olds Distinguished Professor of Psychology & Neuroscience at University of Michigan ‘If you want to know how our ancestors were able to “weaponize their imaginarium to survive”, then this is the book for you. In fact, this book discloses everything you always wanted to know about the brain (but were afraid to ask). It is an incredible resource.’ Karl Friston, Scientific Director for Wellcome Centre for Human Neuroimaging; Professor at Queen Square Institute of Neurology, University College London

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Book SynopsisIn January 1988, aged twelve, Martin Pistorius fell inexplicably sick. Within eighteen months he was mute and wheelchair-bound, being cared for at centres for severely disabled children. What no-one knew is that while Martin''s body remained unresponsive, his mind slowly woke up, yet he could tell no-one, a prisoner inside his own body. During this time, he suffered abuse of a kind that is barely imaginable, yet still he kept the spirit of hope alive. It wasn''t until he was twenty-three that a gentle therapist realised he was alert to everything and, along with his parents, assisted his road to recovery. Since then, against all odds, he has fallen in love, married, and now runs a thriving web design business. Martin''s extraordinary story is a deeply moving account of the power of love.

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Book SynopsisA collection of groundbreaking research by a leading figure in neuroscience.Trade Review"[C]hallenges professionals who interact therapeutically, educationally, clinically or even socially with vulnerable populations to share knowledge and work across our specific disciplines, to prevent, identify and treat mental illness." -- Journal of Unified Psychotherapy and Clinical Science"Stephen Porges has been at the forefront of the investigation of the interplay between neurophysiological processes and developmental status.... It is with The Polyvagal Theory that Porges now presents, in a well-delineated and articulated volume, a highly testable set of hypotheses regarding how the human (and more broadly, mammalian) nervous system has evolved to promote affective regulation and social interaction.... I commend Porges on this effort. Substantial research across a significant career has been well considered and integrated into a quite engaging and stimulating model regarding the relationship between the heart and the brain." -- PsycCritiques"[O]ne of the most important books written on the nervous system in the last fifty years. Porges’s ambitious, meticulous, synthetic theory provides a missing link between mind and the nervous system. It also helps explain, in fine detail, how our individual nervous systems influence, and are influenced by, our interactions with others. Suddenly we understand things novelists have described for centuries: how it is that a facial expression, a gesture, a certain tone of voice, can trigger a radical mental reorganization, and lead to engagment, and how our mental and nervous system states shift. Porges’s studies and his theory of the social vagus represents a major advance in human knowledge, and is already improving the practice psychotherapy and mind-body medicine." -- Norman Doidge, MD, author, The Brain That Changes Itself"A truly revolutionary perspective on human nature, Porges challenges current theory, illuminates old findings so that we see them differently, and raises dozens of questions for new scientific research. The reach is broad, the depth astounding." -- Paul Ekman, PhD, Professor Emeritus, University of California at San Francisco, and President & Founder, Paul Ekman Group, LLC"The Polyvagal Theory is at the leading edge of psychosomatic medicine and body-mind therapies. It is a vital contribution to scientifically-informed clinical practice. Psychologists, analysts, physicians, bodyworkers, and educators are provided with an essential map to help guide them in tracking the psychophysiological states of their clients, discern where they are ‘stuck,’ and help them to heal and move forward in life. Dr. Porges’s great contribution is now compiled in this one astounding comprehensive volume. It is a must-read for clinicians and psychobiological researchers." -- Peter A. Levine, PhD, author of In Unspoken Voice: How the Body Releases Trauma and Restores Goodness

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Book Synopsis'A mine of treasures, a source of visions, a microcosm of human experience and suffering, the philosopher's stone: Migraine is a remarkable achievement' - Sunday Telegraph. Migraine is an age-old – the first recorded instances date back over two thousand years – and often debilitating condition, affecting a 'substantial minority' of the population across the globe. In Migraine, Oliver Sacks offers at once a medical account of its occurrence and management; an exploration of its physical, physiological, and psychological underpinnings and consequences; and a meditation on the nature and experience of health and illness.Trade ReviewIt delves into the workings of the brain with brilliant complexity, and should be required reading for migraine sufferers or those with an intellectual bent. * Cosmopolitan *Migraine is full of those wondrous insights that have made Oliver Sacks the most accessible and at the same time the most magisterial of doctors. -- Anita Brookner * Spectator *Written with Sacks's customary insight and grace, no book has helped me understand more about the mind-body connection. -- Hilary Mantel * Mail on Sunday *

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Book Synopsis''If you read only one book about attention deficit disorder, it should be Delivered from Distraction.'' Michael Thompson, Ph.D., New York Times bestselling co-author of Raising CainIn 1994, Driven to Distraction sparked a revolution in our understanding of attention deficit disorder. Widely recognized as the classic in the field, the book has sold more than a million copies. Now a second revolution is under way in the approach to ADD, and the news is great. Drug therapies, our understanding of the role of diet and exercise, even the way we define the disorder - all are changing radically. And doctors are realizing that millions of adults suffer from this condition, though the vast majority of them remain undiagnosed and untreated. In this new book, Drs Edward M. Hallowell and John J. Ratey build on the breakthroughs of Driven to Distraction to offer a comprehensive and entirely up-to-date guide to living a successful life with ADD.<Trade ReviewDelivered from Distraction is just what it promises. In this remarkable volume, Ned Hallowell and John Ratey bring the latest information on ADD to homes and hearts everywhere, conveying the burgeoning scientific information with humor, hope, and clarity. As the authors point out, ADD needn't be a sentence to secondhand status. The ADDer who hearkens to their sage and practical whole-life advice will make the most of his or her talents. This book is certain to be a classic for the next decade. * Peter S. Jensen, M.D., Ruane Professor of Child Psychiatry, director, Center for the Advancement of Children’s Mental Health, Columbia University/New York State Psychiatric Institute *If you read only one book about attention deficit disorder, it should be Delivered from Distraction. No two psychiatrists in America have thought more deeply about ADD than Ned Hallowell and John Ratey, and no one writes about it with more feeling, understanding, and accuracy. Most important, Hallowell and Ratey share their wisdom about living a good life with ADD. What an optimistic and helpful book! * Michael Thompson, PhD, 'New York Times' bestselling co-author of 'Raising Cain' *Edward Hallowell has written a comprehensive, easy-to-understand book on ADD. This is clearly the definitive source of information on Attention Deficit Disorder. * Harold S. Koplewicz, MD, director, Child Study Center, New York University School of Medicine *A deeply wise and truly helpful book, written with frankness, humor, and tremendous empathy. As a pediatrician, I have been recommending Driven to Distraction to parents for many years, and this new book brings the reader fully up to date in a rapidly changing field, combining the important information about the science and treatment of ADD with powerful advice about getting through life, succeeding in life, and enjoying life. * Perri Klass, MD, co-author of 'Quirky Kids' *What is unique and particularly valuable in Hallowell and Ratey's approach is the hopeful message, insistently repeated, that 'at the heart of ADD lies a bonanza of wonderful qualities,' and that in treatment, these strengths and talents can and should be identified and developed. * Charles Magraw, MD, past president, Boston Psychoanalytic Society and Institute *

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Book SynopsisIn this work, Karen Horney explores the basic structure of neuroses in the context of their cultural assumptions.

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Book SynopsisIt’s never been this urgent to build employee relationships that spark higher brain thinking and the skills to connect with people to encourage their highest performance. In other words, it’s vital to engage team members’ upper brains, which control critical reasoning, judgment, and creativity. When that positive connection is lacking, leaders risk provoking team members’ lower brains—which govern fear and survival behaviors—and creating a toxic workplace. Research shows that a leader’s behavior is the most important predictor of a team’s success. Leading with Your Upper Brain helps you understand why. It provides an innovative framework to shift your behavior in ways that help employees tap into their upper-brain resources that drive higher levels of performance. The authors use cutting-edge neuroscience research to illustrate how a positive connection with their leader builds trust and affects team members’ brain function that leads to overall team success. They share a modern, science-based approach to performance management and leadership development that fits any organization. Each chapter offers key takeaways, tips, and questions to help you put the principles into practice.

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Book SynopsisSince 1950 there has been a steady increase in mental ill-health across the population. At the same time there has been a similar steady decline in IQ. There is strong evidence of dumbing down' right across society.

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Book SynopsisA revised edition of the New York Times bestseller that will help you conquer ADD—from the author of The End of Mental Illness. Attention deficit disorder (ADD) is a national health crisis that continues to grow—yet it remains one of the most misunderstood and incorrectly treated illnesses today. Neuropsychiatrist Daniel G. Amen, MD was one of the first to identify that there are multiple types beyond just purely hyperactive or inattentive ADD, each requiring a different treatment. Now, in this all-new, revised edition, Dr. Amen again employs the latest medical advances in the field, including the largest brain imaging study ever completed on patients with ADD, to identify, examine, and demystify the 7 distinct types of ADD and their specific treatments. With updated recommendations for nutraceuticals and/or medications targeted to brain type, diet, exercise, lifestyle interventions, cognitive reprogramming, parenting and educational str

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Book SynopsisCan you imagine not being able to speak or communicate? The silence, the loneliness, the pain. But, inside you disappear to magical places, and even meet your best friend there. However, most of the time you remain imprisoned within the isolation. Waiting, longing, hoping. Until someone realises your potential and discovers your key, so your unlocking can begin. Now you are free, flying like a wild bird in the open sky. A voice for the voiceless.Jonathan Bryan has severe cerebral palsy, a condition that makes him incapable of voluntary movement or speech. He was locked inside his own mind, aware of the outside world but unable to fully communicate with it until he found a way by using his eyes to laboriously choose individual letters, and through this make his thoughts known.In Eye can Write, we read of his intense passion for life, his mischievous sense of fun, his hopes, his fears and what it's like to be him. This is a powerful book from an incredible young writer whose writing ability defies age or physical disability - a truly inspirational figure.Foreword by Sir Michael MorpurgoA portion of the proceeds from the sale of this book will be donated to Jonathan Bryan's charity, Teach Us Too.http://www.teachustoo.org.uk/Trade ReviewThe summer book you have to read * Hello Magazine *

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Book SynopsisWitness the dramatic unfolding of the human form in all its potential. Join John E. Upledger, D.O.,O.M.M., as he takes you from the first union of sperm and egg through the development of the complex circuitry that makes up the human brain.You’ll learn about birth, growth, function and dysfunction, and how all these aspects influence physical, mental, and emotional well-being. You’ll discover problems that can alter brain and spinal cord development in each of the first eight weeks of pregnancy, and then monthly right through delivery.Perhaps most importantly, Dr. Upledger outlines a series of simple physical tests that can help determine the status of a baby’s central nervous system and, to some extent, the peripheral nervous system. Then he shows you, step-by-step, how potential problems might be treated using CranioSacral Therapy and related therapeutic approaches.This breakthrough book empowers parents with knowledge to help them make practical decisions concerning the health of their children. And it crosses the boundaries of many disciplines, including embryology, obstetrics, pediatrics, neurology, and CranioSacral Therapy. A Brain Is Born is as valuable to expectant parents as it is to those who work with children every day.

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Book SynopsisTable of ContentsForeword xvii Introduction 1 Part 1: Getting to Know PD 5 Chapter 1: Parkinson’s Disease: The Big Picture 7 Chapter 2: Considering Possible Causes and Risk Factors 19 Chapter 3: Sizing Up Symptoms, Signs, and Stages 33 Part 2: Making PD Part — But Not All — of Your Life 47 Chapter 4: Getting an Accurate Diagnosis 49 Chapter 5: You’ve Been Diagnosed — Now What? 69 Chapter 6: Drafting Your Healthcare Team and Making a Game Plan 85 Chapter 7: Choosing How and When to Share Your News 101 Chapter 8: Young Onset Parkinson’s and Lewy Body Dementia 113 Part 3: Crafting a Treatment Plan Just for You 131 Chapter 9: Eat Well, Sleep Well, and Exercise 133 Chapter 10: Managing PD Symptoms with Prescription Medicines 171 Chapter 11: When Surgery Is an Option 187 Chapter 12: Considering Complementary and Alternative Medicine Therapies 199 Chapter 13: Combating Anxiety, Depression, and Apathy 215 Chapter 14: Clinical Trials and Your Role in the Search for a Cure 235 Part 4: Living Well with PD 247 Chapter 15: Maintaining Healthy Relationships 249 Chapter 16: PD in the Workplace 267 Chapter 17: Adjusting Your Routine While Your PD Progresses 281 Part 5: Coping with Advanced PD 297 Chapter 18: Facing the Progression of PD Symptoms 299 Chapter 19: When Care Partners Become Caregivers 319 Chapter 20: Putting Your Financial and Legal House in Order 343 Chapter 21: It’s Just Bricks and Mortar: Housing Options You Can Live With 359 Part 6: The Part of Tens 379 Chapter 22: Ten Ways to Deal with Difficult Feelings 381 Chapter 23: Ten Ways to Care for Your Care Partner 387 Chapter 24: Ten Ways You Can Make a Real Difference 393 Appendix A: Glossary 399 Appendix B: Additional Resources 409 Index 415

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Book Synopsis*As featured on Steven Bartlett’s Diary of a CEO podcast* For those fascinated by neurology and for fans of The Man Who Mistook His Wife for a Hat comes a powerful exploration of the mind during night time. Here are the mysteries of sleep, explained – from known conditions to the extreme.  ‘The Secret World of Sleep interweaves bizarre real life stories with cutting edge neurological science in the true tradition of Oliver Sacks. A fascinating read.' Martha Kearney, BBC Radio 4   World-renowned neurologist and sleep expert, Doctor Guy Leschziner, takes you through various sleep conditions and how they arise and affect people. Insomnia, narcolepsy, night terrors and apnoea are just some of the conditions afflicting those struggling with sleep. Then there are the extreme cases. The people frightened into paralysis by hallucinations. The woman in a stTrade Review‘With my job on Today, I have become obsessed with sleep. The Secret World of Sleep interweaves bizarre real life stories with cutting edge neurological science in the true tradition of Oliver Sacks. A fascinating read.’ -- Martha Kearney, BBC Radio 4'Casebooks of neurological disorders are often strange and wonderful, but this one is special. Guy Leschziner is a consultant neurologist at Guy’s and St Thomas’s who specialises in sleep problems. And his patients experience the most extraordinary things…' -- James McConnachie * Sunday Times *‘The Secret World of Sleep will not promise to cure your insomnia, but it does make for an entertaining and thought-provoking bedtime read.’ * Guardian *'The Secret World of Sleep combines two of my favourite things – humanity and medical science. Dr Leschziner weaves wonderful stories that highlight how sleep disorders affect the lives and health of patients and their families. Along the way we are guided into the fantastic science of sleep. What a wonderful journey!' -- Meir Kryger MD FRCPC, Professor, Yale University, author of Mystery of Sleep

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Book SynopsisHIGHLY COMMENDED for the British Medical Awards book prize for Popular MedicineUp to 10% of people will suffer a mild head injury (or ''mild traumatic brain injury'') in their lifetime and up to 50% of those people will also find they have lingering post-concussion symptoms in the months or years afterwards. These symptoms can include headaches, dizziness, fatigue, irritability, sleep disturbance, reduced day-to-day memory, poor concentration, taking longer to think, ''muzzy'' headedness, depression, anxiety, tinnitus, blurred or double vision, sensitivity to light or noise, frustration, nausea, restlessness and sensitivity to alcohol. In such circumstances the ''mild'' head injury may feel anything but mild. This is particularly so if large areas of your day to day life are affected. People in these circumstances can have their difficulties compounded by the very different explanations for their persisting difficulties. These usually involve receiving con

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Book Synopsis'The story of a disease that plunged its victims into a prison of viscous time, and the drug that catapulted them out of it' – Guardian Hailed as a medical classic, and the subject of a major feature film as well as radio and stage plays and various TV documentaries, Awakenings by Oliver Sacks is the extraordinary account of a group of twenty patients.Rendered catatonic by the sleeping-sickness epidemic that swept the world just after the First World War, all twenty had spent forty years in hospital: motionless and speechless; aware of the world around them, but exhibiting no interest in it – until Dr Sacks administered the then-new drug, L-DOPA, which caused them, temporarily, to awake from their decades-long slumber . . .Trade ReviewA brilliant and humane book. * Observer *It makes you aware of what a knife edge we live on. -- Doris LessingNot only a collection of astonishing case histories, Awakenings is also a memoir, a moral essay and a romance. It is a work of genius. * Washington Post *

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Book Synopsis'I loved it. She is in my view the best science writer around - a true descendant of Oliver Sacks' Sathnam Sanghera, author of The Boy with the TopknotThe brain is the most complex structure in the universe. In Brainstorm the Wellcome Prize-winning author of It’s All in Your Head uncovers the most eye-opening symptoms medicine has to offer.‘Powerfully life-affirming... Brainstorm is testament to O'Sullivan's unshowy clarity of thought and her continued marvelling at the mysteries of the brain’ GuardianBrainstorm examines the stories of people whose symptoms are so strange even their doctor struggles to know how to solve them. A man who sees cartoon characters running across the room; a teenager who one day arrives home with inexplicably torn clothes; a girl whose world turns all Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe, and neurologists must puzzle out life-changing diagnoses from the tiniest of clues – it’s the ultimate in medical detective work. In this riveting book, one of the UK’s leading neurologists takes you with her as she follows the trail of her patients’ symptoms: feelings of déjà vu lead us to a damaged hippocampus; spitting and fidgeting to the right temporal lobe; fear of movement to a brain tumour; a missed heart beat to the limbic system.It’s a journey that will open your eyes to the unfathomable intricacies of the brain, and the infinite variety of human capacity and experience.Trade ReviewPowerfully life-affirming... Brainstorm is testament to O'Sullivan's unshowy clarity of thought and her continued marvelling at the mysteries of the brain -- Colin Grant * Guardian *A fascinating attempt to draw the lay reader into understanding more about the function and malfunction of the brain by using real-life stories... O'Sullivan is a good, clear writer, lacks pomposity and avoids cliché -- her first book, It's All in Your Head, won the Wellcome Prize -- David Aaronovitch * The Times *O'Sullivan writes beautifully and is full of wonder... a pleasure -- John Preston * Mail on Sunday *A tremendously interesting work of medical humanity... The main effect of this fascinating collection of clinical stories, by the end, is to make any reader without brain dysfunction exceedingly grateful for the fragile miracle going in inside their own skull every second -- Steven Poole * Daily Telegraph *I loved it. She is in my view the best science writer around - a true descendant of Oliver Sacks * Sathnam Sanghera, author of The Boy with the Topknot *

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Book SynopsisBody Awareness as Healing Therapy: The Case of Nora is Moshe Feldenkrais'' classic study of his work with Nora, a woman who has suffered a severe stroke and lost her neuromuscular coordination, including the ability to read and write. Feldenkrais uses rational and intuitive approaches to help his student relearn basic motor skills. One can observe here the groundwork of Feldenkrais'' extraordinary insights which became known as the Feldenkrais Method. We follow his detailed descriptions of the trial and error process which led him to see the ingredients that were needed to help Nora reshape her attention, perception, imagination and cognition.

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Book SynopsisSleep. Memory. Pleasure. Fear. Language. We experience these things every day, but how do our brains create them? Your Brain, Explained is a personal tour around your gray matter. Neuroscientist Marc Dingman gives you a crash course in how your brain works and explains the latest research on the brain functions that affect you on a daily basis.You''ll also discover what happens when the brain doesn''t work the way it should, causing problems such as insomnia, ADHD, depression, or addiction. You''ll learn how neuroscience is working to fix these problems, and how you can build up your defenses against the most common faults of the mind.Along the way you''ll find out: Why brain training games don''t prevent dementia What it''s like to remember every day of your life as if it were yesterday Which popular psychiatric drug was created from German rocket fuel How you might unknowingly be sabotaging your sleep

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Book SynopsisTable of ContentsSection I: Classic Anatomic Neurology 1. First Encounter with a Patient: Examination and Formulation 2. Central Nervous System Disorders 3. Psychogenic Neurologic Deficits 4. Cranial Nerve Disorders 5. Peripheral Nerve Disorders 6. Muscle Disorders Section II: Major Neurologic Symptoms 7. Dementia 8. Aphasia and Related Disorders 9. Headaches 10. Epilepsy 11. TIAs and Strokes 12. Visual Disturbances 13. Congenital Cerebral Impairments 14. Neurologic Aspects of Chronic Pain 15. Multiple Sclerosis 16. Neurologic Aspects of Sexual Function 17. Sleep Disorders 18. Involuntary Movement Disorders 19. Brain Tumors, Metastatic Cancer, and Paraneoplastic Syndromes 20. Lumbar Puncture and Imaging Studies 21. Neurotransmitters and Drug Abuse 22. Traumatic Brain Injury Appendix 1 Appendix 2 Appendix 3 Appendix 4 Additional Review Questions and Answers Index

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Book SynopsisA fascinating account by one of the world's leading neurologists of the profound influence of William Burroughs on his medical career. Lees relates how Burroughs, author of Naked Lunch and troubled drug addict, inspired him to discover a ground-breaking treatment for Parkinson's Disease. Lees journeys to the Amazonian rainforest in search of cures for Parkinson's Disease, and through self-experimentation seeks to find the answers his patients crave. He enters a powerful plea for the return of imagination to medical research.

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Book SynopsisPaediatric Neurology returns for a fourth edition with all the knowledge and guidance you need to investigate, diagnose, and treat common and rare neurological conditions in paediatrics. This unique guide has been fully updated to reflect the latest developments in the field, including a more in-depth look at genetic investigations, new material on neuroinflammation and neuromuscular disorders, extensive updates on epilepsy and other neurology conditions affecting children, and a fully revised pharmacopoeia. Vibrant and informative, the text includes diagrams and tables to enhance understanding and learning, while keeping the book firmly grounded in situations you are likely to encounter in real life.Part of the Oxford Specialist Handbook series that spans the whole of Paediatrics, this unique guide should be at the fingertips of every practising or aspiring paediatric neurologist.

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Book Synopsis'Hugely entertaining' Guardian'Fascinating' Mail on SundayIn 1882, Jean-Martin Charcot was the premiere physician in Paris, having just established a neurology clinic at the infamous Salpêtrière Hospital, a place that was called a 'grand asylum of human misery'. Assessing the dismal conditions, he quickly upgraded the facilities, and in doing so, revolutionized the treatment of mental illness. Many of Charcot's patients had neurosyphilis (the advanced form of syphilis), a disease of mad poets, novelists, painters, and musicians, and a driving force behind the overflow of patients in Europe's asylums. A sexually transmitted disease, it is known as 'the great imitator' since its symptoms resemble those of almost any biological disease or mental illness. It is also the perfect lens through which to peel back the layers to better understand the brain and the mind. Yet, Charcot's work took a bizarre turn when he brought mesmerism - hypnotism - into his clinic, abandoning his pursuit of the biological basis of illness in favour of the far sexier and theatrical treatment of female 'hysterics', whose symptoms mimic those seen in brain disease, but were elusive in origin. This and a general fear of contagion set the stage for Sigmund Freud, whose seductive theory, Freudian analysis, brought sex and hysteria onto the psychiatrist couch, leaving the brain behind. How The Brain Lost Its Mind tells this rich and compelling story, and raises a host of philosophical and practical questions. Are we any closer to understanding the difference between a sick mind and a sick brain? The real issue remains: where should neurology and psychiatry converge to explore not just the brain, but the nature of the human psyche?Trade ReviewAbsorbing and scholarly... A twin biography of psychiatry and neurology, their study charts this uneasy relationship from marriage to divorce to reconciliation even as fundamental questions about the nature of mental illness remain... Hugely entertaining. * Guardian *A rollicking ride, patient by patient, through the history of two conditions, hysteria and neurosyphilis. * The Times *Central to this book is the ongoing dispute regarding which mental illnesses can be attributed to physical abnormalities within the brain and which originate in the mind, or consciousness. The authors emphasise that in many cases we still cannot be sure... Along the way, their investigations exhume some unforgettable scenes and characters... Fascinating * Mail on Sunday *Rich, compassionate and passionate... Sceptical of the excesses of both psychological and biological reductionism, it is a refreshing call for an intellectual reset and disciplinary rapprochement. -- Anne Harrington * Nature *This aptly titled book picks up where Oliver Sacks left off in examining the behavioral characteristics of neurobehavioral syndromes in an effort to span the gap that has historically separated the twin disciplines of the brain, neurology and psychiatry. * Jeffrey A. Lieberman, author of Shrinks: The Untold Story of Psychiatry *Through tales of eminent physicians and their suffering patients, replete with sex, drugs, and magnetically-induced hypnotism, we learn how a bacterium that deprived countless souls of their reason also helped scientists discover a role for brain biology in mental illness. * Alan Jasanoff, PhD, author of The Biological Mind *Ropper and Burrell have written an insightful, fantastically readable analysis of what was once called "hysteria." Also, by studying how things can go wrong, we learn a great deal about the working of the human mind when things go right. * Elizabeth Loftus, author of Eyewitness Testimony *Table of Contents0: INTRODUCTION 1: A CLINICAL LESSON 2: WHAT IS A DISEASE? 3: PYGMALION AND GALATEA 4: THE INVENTION OF HYSTERIA 5: THE PAPUAN IDOL 6: HEARTS OF DARKNESS 7: THE SOUL OF A NEW DISEASE 8: THE UNSETTLED TERRITORIES OF THE MIND 9: THE DIFFICULT CASE OF ANNA O. 10: THE DEVIL AND ADRIAN LEVERKÜHN 11: SEX AND THE NEW WOMAN 12: WINNING THE BATTLE AND LOSING THE WAR 13: THE PSYCHIC INTERPRETATION OF DISEASE 14: A BEAUTIFUL NAME FOR A HORRIBLE DISEASE 15: MEDICINAL LOBOTOMY: THE INVENTION OF THORAZINE 16: THE FEVERED DREAM OF A SCIENTIFIC PSYCHOLOGY 17: THE LESSONS OF NEUROSYPHILIS

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Book SynopsisBorn out of the excitement of a convergence of ideas and passions, this book provides a synthesis of the work of researchers, clinicians, and theoreticians who are leaders in the field of trauma, attachment, and psychotherapy.Trade Review"Trauma has returned to center stage in our clinical and theoretical thinking. This book enriches our understanding of trauma from all the pertinent perspectives. It will be invaluable for all in the field, both for treating people and thinking about trauma. " -- Daniel S. Stern, MD, Adjunct Professor of Psychiatry, Cornell Medical School; author of The Interpersonal World of the Infant"This remarkable collection of articles summarizes much of the best current thinking on trauma, attachment research, neurobiology, and its application to psychodynamic psychotherapy. It is an outstanding achievement." -- Beatrice Beebe, PhD, Clinical Professor of Psychology in Psychiatry, NYS Psychiatric Institute, Columbia University"This volume provides much more than a compelling set of models for healing trauma—it also delivers a state of the art account of the causes and consequences of trauma. The editors, Marion Solomon and Daniel Siegel, are to be congratulated for bringing together so cohesively some of the most powerful voices in the field. This book will clarify understanding of trauma through eight chapters presenting the latest significant findings in neuroscience, developmental and clinical psychology, and psychiatry. Those training or working with victims of trauma and their families will find this resource indispensable." -- Howard Steele, PhD, Director, Attachment Research Unit, University College, London; Editor, Attachment & Human Development"This is an extraordinary book. It provides an up-to-the-minute integration of attachment trauma and neuroscience. Each contribution provides an essential chart to guide the therapist in understanding this most difficult group of clients. Taken together, the chapters compose a veritable atlas mapping this world of the unbearable and unthinkable. Without such theoretical and practical guides, the therapist working with trauma can become as vulnerable as the client she or he attempts to heal." -- Peter Fonagy, PhD, FBA, Freud Memorial Professor of Psychoanalysis at University College London and Director, Child and Family Center, The Menninger Clinic, Topeka, KS

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Book SynopsisTable of Contents1. Clinical cases from neuro-oncology 2. Clinical cases from functional neurosurgery 3. Clinical cases from paediatric neurosurgery 4. Clinical cases of neurotrauma 5. Clinical cases from vascular neurosurgery 6. Clinical cases from voice disorders

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Book SynopsisHunter, detective, scientist - Nancy is all these, and a friend to people everywhere who are affected by a fatal, inherited sickness called Huntington's disease and other diseases of the brain. This book presents the story of this courageous and dedicated woman whose passion for science is both personally and intellectually satisfying.Table of Contents1 Sample Chapter 1: The Dancing Disease

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Book SynopsisTable of ContentsBlue is new Section I Overview of the Nervous System Neurons and Their Properties Anatomical and Molecular Properties Neuronal Ultrastructure Molecular Techniques for Studying Neurons Genetic Models for Studying Neurological Diseases Electrical Properties Neurotransmitter and Signaling Properties Endogenous Opioid Systems Cannabinoid Systems Neuropeptide Neurotransmitters Amino Acid Neurotransmitters Skull and Meninges Brain Brain Stem and Cerebellum Spinal Cord Ventricles and the Cerebrospinal Fluid Vasculature Arterial System Venous System Developmental Neuroscience Postnatal and Adult Neurogenesis Sex Steroid Influences on Brain Development Maternal and Neonatal Stress Influences on the Developing Nervous System Fetal Alcohol Syndrome Section II Regional Neuroscience Peripheral Nervous System Introduction and Basic Organization Somatic Nervous System Somatosensory System Nuclear Neuronal Organization Autonomic Nervous System Spinal Cord Spinal Cord Cross-Section Cytoarchitecture Columnar Organization and Neural Sheet Structure in Spinal Cord Spinal Cord LMN Organization of Inputs and Local Connections Brain Stem and Cerebellum Brain Stem Cross-Sectional Anatomy Lateral View of Whole Brain and Brain Stem Cerebral Cortex Nissl-Stained Histological Sections Periaqueductal Gray Cranial Nerves and Cranial Nerve Nuclei Reticular Formation Raphe Nuclei and Locus Coeruleus Dendrite Bundles and their Functional Role Cerebellum Diencephalon Telencephalon Section III Systemic Neuroscience Sensory Systems Somatosensory Systems Trigeminal Sensory System Sensory System for Taste Auditory System Vestibular System Visual System Motor Systems Lower Motor Neurons Upper Motor Neurons Cerebellum Basal Ganglia Autonomic-Hypothalamic-Limbic Systems Autonomic Nervous System Hypothalamus and Pituitary Anterior Pituitary Hormone and Target Feedback Hypothalamus: Afferent and Efferent Pathways Estrogen and Androgen Effects on Behavior Glucocorticoid Effects in the Periphery and Central Consequences Catecholamine Effects in the Periphery and Central Consequences Oxytocin and Vasopressin Effects on Behavior Limbic System Olfactory System Orbitofronal Cortex Prefrontal Cortex Amygdala and Behavior Ventral Tegmental Area and Mesolimbic and Mesocortical Systems Nucleus Accumbens Bed Nucleus of the Stria Terminalis Insular Cortex Nucleus Basalis of Meynert Circumventricular Organs Section IV Global Brain Functions Dementias Alzheimer's Disease and Its Mechanisms Neuropsychiatric Disorders Schizophrenia Unipolar and Bipolar Depression Panic and Anxiety Disorders Post-Traumati Stress (PTSD) Tramatic Brain Injury (TBI) Brain Substrates and Addictive Behaviors Opioid Addiction and Abuse Aging and the Nervous System Memory and Concentration Consciousness Focus and Attention Coma Music and the Brain

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