Medicine / Healthcare: general issues / topics Books

3580 products


  • 101 Careers in Public Health

    Springer Publishing Co Inc 101 Careers in Public Health

    Out of stock

    Book SynopsisThe public health landscape is one of the most rapidly growing and cutting-edge fields at the moment and, in the wake of the global COVID-19 pandemic, there has never been a more meaningful time to enter the field. This thoroughly updated and revised third edition of 101+ Careers in Public Health continues to act as a career guide both for students seeking a first job in the field of public health and for anyone seeking guidance on how to best navigate the next stages of an existing career. Discussing not only emerging career paths but also traditional and familiar job types in public health, this book offers comprehensive advice and practical tips. It includes a wide survey of career profiles, including careers closely involved with pandemic response, climate change, technology and data science, and social justice advocacy.This third edition continues to provide a clear introduction to the history of public health with detailed descriptions of the many educational pathways that lead to public health careers. The book explores more than 120 different jobs in public health, with complete job descriptions, educational requirements, and future outlooks in addition to public health profiles from working professionals in the field. Whether interested in positions in government, healthcare, non-governmental organizations, technology, research, academia, philanthropic organizations, global health, consulting, or other private sector companies, this exciting third edition of 101+ Careers in Public Health provides excellent career guidance and produces helpful self-reflection when deciding on a public health career path.Key Features: Provides an introduction to the important competencies, training, and requirements needed to secure job opportunities at different career stages Includes step-by-step advice on how to network, apply, and interview for the job that best matches your interests, complete with a sample resume and cover letter Presents 50 new interviews from early career, management, and leadership positions as well as job descriptions for 20 occupations new to this edition Expanded coverage on global health and related opportunities, in addition to jobs in data science and technology Offers career advice for entry-level candidates and also for anyone looking to change careers

    Out of stock

    £32.39

  • PANCEPANRE Challenge Quick QA Review

    Springer Publishing Co Inc PANCEPANRE Challenge Quick QA Review

    Out of stock

    Book SynopsisIncludes 6 months'' free ExamPrepConnect Digital Access with print purchase!Test your PANCE or PANRE readiness challenge-bowl style with PANCE/PANRE Challenge: Quick Q&A Review. This book offers 1000 spontaneous recall and higher-level reasoning questions with short answers and quick explanations to test your clinical and professional knowledge WITHOUT using multiple answer choices as a crutch.One of the most essential high-stakes exam study tips you''ll ever receive is to be able to answer test questions without looking at the answer choices. If you can achieve this successfully, there''s no doubt you''ll pass the PANCE or PANRE with flying colors.Organized by body system and based on all facets of the NCCPA exam blueprint, these questions challenge you to think quickly as if you were in a true patient care environment and motivate you to use critical thinking skills to apply key medical concepts.Authored by seasoned PA educators who are also challenge-bowl question writers and coaches with decades of clinical experience, this book offers you a novel approach to supplement your exam preparation experience. Not only will this book help you prepare for your certification or recertification exam, but it also provides an authentic tool to support success for your didactic and clinical training, rotation and end-of-curriculum exams, and even OSCEs!Key Features Aligned with the current NCCPA blueprint by organ systems and task categories Contains 1000 spontaneous recall and higher-level reasoning Q&A Encourages self-reflection to help learners identify strengths and weaknesses Promotes self-directed learning to solidify concepts Intentionally excludes multiple answer choices to prompt learners to think on their feet as if they were in an actual clinical scenario Content available digitally via ExamPrepConnect for study on the go ExamPrepConnectthe digital study platform that guides you confidently through your exam prep journey. With this score-boosting study tool, you can: Review all the high-quality content from the book Get organized by using the personalized study plan based on your exam date Access all 1000 questions in digital flashcard mode to enhance rapid recall skills Study by topic to identify your strengths and gaps in knowledge Connect and chat with fellow PANCE and PANRE test takers using the discussion board Play games to make studying fun See access code details inside the book.PANCE and PANRE are administered by the National Commission on Certification of Physician Assistants (NCCPA), which does not endorse this product or have a proprietary relationship with Springer Publishing

    Out of stock

    £38.69

  • Oncology Clinical Trials Successful Design

    Springer Publishing Co Inc Oncology Clinical Trials Successful Design

    Out of stock

    Book Synopsis

    Out of stock

    £130.49

  • Primary Care

    Springer Publishing Company Primary Care

    Out of stock

    Book SynopsisA complete, state-of-the-art bible of interprofessional primary care in one easy-to-use resource for Interprofessional Primary Care A truly interprofessional primary care textbook, created by DNPs/APRNs, MDs, PharmDs, PAs, CNSs, and CNMs Evidence-based practice guidelines for Primary Care Includes community care, team work, and wellness coachings Strong guidance on differential diagnosis, disease prevention, risk reduction and lifestyle management Across the lifespan focus PLUS gender, occupational and palliative care considerations Case Studies in PPT format available to faculty adopting the text This second edition of Primary Care delivers succinct, current, and integrated information on the assessment, differential diagnosis, treatment, and management of individuals with commonly seen conditions in primary care settings. Written and edited by APNs, MDs, PAs, PharmDs and other health professiona

    Out of stock

    £83.69

  • Public Health

    Springer Publishing Co Inc Public Health

    Out of stock

    Book SynopsisNow in its second edition, Public Health: An Introduction to the Science and Practice of Population Health ?is expanded in both scope and depth of content to better aid students who are launching their public health studies and preparing for professions in the field. This edition features a greater emphasis on the social determinants of health, health equity, prevention of disease and disability, and the practice of public health.Public Health explores both historical public health issues and contemporary public health challengesincluding environmental justice, food deserts, climate change, and COVID-19through the social ecological lens and with a life course perspective. In addition to establishing a solid knowledge base on the foundations, functions, and core values of public health, the book presents an engaging survey of the social ecological framework and of the demographic factors affecting health at different life stages. The methods of public health,

    Out of stock

    £97.83

  • Public Health Law

    Springer Publishing Co Inc Public Health Law

    Out of stock

    Book SynopsisThis book is very well researched, organized, documented, and referenced. The case studies are relevant to specific public health issues related to race, gender, equity, sexual orientation, poverty, homelessness, drug addiction, andchronic diseases facing U.S. populations in the 21st century. The book offers background information for professionals to try to analyze the root causes and develop public health measures to ameliorate these problems. ---Doody''s Review Service, 4 starsPublic Health Law: Concepts and Case Studies is a practical textbook for students of public health and health policy with comprehensive coverage of core concepts in law across public health sectors. The text builds upon the understanding that law is a significant determinant of health while highlighting essential knowledge of legal issues and laws affecting public health outcomes. Chapters address major topics in United States public health law and take a competency-based approach i

    Out of stock

    £56.04

  • Fostering Learning in Small Groups A Practical

    Springer Publishing Company Fostering Learning in Small Groups A Practical

    Out of stock

    Book Synopsis

    Out of stock

    £63.89

  • Health Equity and Nursing

    Springer Publishing Co Inc Health Equity and Nursing

    Out of stock

    Book Synopsis

    Out of stock

    £59.84

  • The Physician Assistant Students Guide to the

    Springer Publishing Company The Physician Assistant Students Guide to the

    Out of stock

    Book Synopsis

    Out of stock

    £30.39

  • The Science of NearDeath Experiences

    University of Missouri Press The Science of NearDeath Experiences

    15 in stock

    Book SynopsisAs medical and surgical skills improve, innovative procedures can bring back patients who have travelled farther on the path to death than at any other time in history. Hagan and the contributors to this volume engage in evidence-based research on near-death experiences and include physicians who themselves have undergone a near-death experience.Trade Review“A subject currently the focus of intense public discussion, this book conveys a lot of important information in a very brief compass.”—Edward F. Kelly, University of Virginia, author of Beyond Physicalism: Toward Reconciliation of Science and Spirituality

    15 in stock

    £31.30

  • Handbook Of Medicinal Herbs 2Ed Pb 2013 Special

    CRC Press Handbook Of Medicinal Herbs 2Ed Pb 2013 Special

    2 in stock

    Book SynopsisStill considered the definitive work on medicinal herbs and their uses after two decades, the Handbook of Medicinal Herbs has undergone a long-anticipated revision. In the second edition, world-renowned ethnobotanist James A. Duke provides up-to-date data on over 800 of the worldâs most important medicinal plant species. The book contains more species, phytochemicals, proven indications, folk indications, and dosage data than the first edition in a new easier to use format. The in-depth content, the addition of color plates and over 200 black and white illustrations makes this book the most comprehensive resource on medicinal herbs available.NEW IN THE SECOND EDITION: Over 100 color plates, 4 color maps Over 200 black and white illustrations Over 800 medicinal plants â more than twice as many as the previous edition organized alphabetically by common name More herbs from the African, Ayurvedic, Chinese, and Jamu traditions EASY ACCESS TO INFORMATION YOU NEED Designed to give you fast access to the information you need on a regular basis, this new edition is organized more systematically than any other medicinal herb publication. The entries are now arranged alphabetically by common name with the scientific name in parenthesis. Major synonyms are also provided. It has become increasingly clear that there are hundreds of biologically active compounds, often additive or synergistic, in all our plants, foods, spices, herbs, medicinal, and poisonous plants. The debate continues on how these plants work and how they should be used. Blending scientific fact with folk uses and the authorâs personal experience, Handbook of Medicinal Herbs, Second Edition provides the most well rounded discussions of safety, efficacy, toxicity, and rational use found in any herbal reference.Trade Review"Of interest to those who involved in the use of herbs in the medicinal environment…A fine reference work." —J. Elliot, Southeastern Naturalist, 2002 “…the perfect herbal reference. This is a tall order but it is one that James A. Duke, Ph.D., et al, filled quite well…describes most herbs concisely and, in an equally concise manner, evaluates the scientific research on their use. …The extensive references and their convenient coding contribute greatly to the overall value of the new edition…Dr. Duke commented in his introduction that he meant to create a resource to parallel the PDR® for Herbal Medicine. In fact, this updated handbook accomplishes much more. There is no other modern desk reference that combines such a comprehensive materia medica with as much scientific source material. …the botanical reference that most practitioners have been looking for and it comes highly recommended by this practitioner.”— Kathy Abascal, B.S., J.D., Herbalist, Alternative and Complementary Therapies, October 2002“…879 pages of valuable information about more than 800 useful and rarely used medicinal herbs. …the use of shortenings and evaluations and the concise descriptions makes the use of the handbook as a reference book easy.”— Journal of Medicinal and Spice PlantsTable of ContentsAlphabetical listing of herbs by common name.

    2 in stock

    £285.00

  • Modern Neurosurgery

    Taylor & Francis Inc Modern Neurosurgery

    1 in stock

    Book SynopsisFocusing on how increased understanding of brain function affects clinical neuroscience, this title explores the interface between neuroscience advances and clinical neuroscience advances by examining the hypotheses that drive this evolution. It reviews the relevant underpinnings of neurosurgical techniques, treatments, and conceptual approaches.Table of ContentsNeuroscience Hypotheses and Translation into Neurosurgery Practice. Clinical Prospects for Neural Grafting Therapy for Cortical Lesions. Spinal Cord and Peripheral Nerve Regeneration. Cellular Brain Ischemia and Stroke: Neuroprotection, Metabolism and New Strategies for Brain Recovery. Imaging and Functional Mapping of Local Circuits and Epilepsy. Pre-ictal Seizure Detection and Demand Epilepsy Treatment Strategies. Neuroprosthetics and Clinical Realization of Brain-Machine Interfaces. Novel Treatments in Movement Disorders. Advanced in Therapy for High Grade Gliomas. Spinal Dysraphism: The Search for Magic. elayed Cerebral Vasospasm: Hypotheses and Advances. Endovascular Treatment Advances. Neuroscience ICU Therapeutics and Diagnostics.New Directions and Therapeutics in Spine Treatment. Clinical Research in Surgery. Neurosurgery Teaching Techniques.

    1 in stock

    £175.75

  • Cytokines and the CNS

    Taylor & Francis Inc Cytokines and the CNS

    1 in stock

    Book SynopsisProvides Insight into How Cytokine Action Impacts the Physiology and Pathology of the CNS. As with the first edition of Cytokines and the CNS, this completely updated and revised edition introduces neurobiologists to cytokine biology and immunologists to the unique functions of cytokines in CNS physiology. The dramatically accelerating interest in cytokines and cytokine/chemokine signaling over the past several years has encouraged an explosion of literature on cytokines. The similarity between factors involved in inflammation or immunity, and those implicated in neural development, physiology, and repair has become so apparent that familiarity with cytokines must now be considered an essential element in the neurobiologist's cognitive tool-kit. Conversely, for immunobiologists, the concepts elaborated by neurobiologists to understand developmental patterning and networked organ function continue to evolve in such a way that comprehension of cytokine action in the CNS Table of ContentsThe CNS: Cells, Tissues and Reactions to Insult. Cytokines – Wherefrom and Whereto. Cytokine Receptors. Cytokines and Signaling. Inflammatory Complexities in the CNS: New Insights into the Effects of Intracellular Redox State and Viral Infection in Modulating the Biology of Oligodendrocytes and Their Precursor Cells. Cytokines and Development of the Nervous System. Cytokines and CNS Inflammation. Cytokines and Immune Regulation in the Nervous System. Cytokines and Neurodegeneration. Cytokine Expression and Signaling in Brain Tumors. Cytokines and Defense Pathology of the CNS. Cytokines and Multiple Sclerosis. Cytokines in Brain Trauma and Spinal Cord Injury. Cytokine-Based Therapeutics for Intrinsic CNS Disease Processes.

    1 in stock

    £194.75

  • Filing Patents Online

    Taylor & Francis Inc Filing Patents Online

    Out of stock

    Book SynopsisThe average cost of an uncomplicated patent application filing is about $10,000. This high cost can leave thousands of inventors out in the cold. Filing Patents Online: A Professional Guide is a complete manual that walks inventors through each step of filing and prosecuting the patent online at a fraction of the cost. The online filing system recommended in the book allows continuous monitoring of the review status and for a much faster approval than the traditional route. Drawing from the many years of the author''s experience as both an inventor and a patent agent, this guide teaches the methods of research, planning, and the art of writing winning claims that will result in commercially valuable patents.Table of ContentsChapter 1 -- The Patent Filing Systems -- Introduction -- A Brief History of the Internet -- U.S. Laws and Systems -- International Patent Laws, Processes, and Systems -- The Paris Convention -- Patent Cooperation Treaty -- European Patent Convention -- Online and Electronic Filing Requirements -- Chapter 2 -- Patent Application Essentials -- Introduction -- Key Definitions -- Misconceptions -- Introduction to Patent Practice -- Purpose of Patent -- Laws Governing Patents -- Important Dates -- Parts of a Patent -- Drawings (35 USC 113) -- Specification (35 USC 112) -- 112 f1 Requirement: Description, Enablement, and Best Mode -- 112 |2 Requirement: Parts of a Claim -- Reading a Claim -- Punctuation of Claim -- Definiteness of Claim -- Narrowing of Claim -- Dependent Claims (§112 f3-4) -- Multiple Dependent Claims (§112 |5) -- Dominant-Subservient Claims -- Means-Plus-Function Clauses (§112 |6) -- Process Claims -- Step-Plus-Function Clauses -- Ranges -- Negative Limitations -- Relative and Exemplary Terminology -- Markush Group -- Markush Alternates -- Jepson-Type Claims, Improvement Claims -- Mixed-Class Claims -- Product-by-Process Claims -- Novelty and Loss of Right to Patent: §102 -- Date of Invention -- Status of Invention -- Types of §102 Events -- §102(a) -- §102(b) -- §102(c) -- §102(d) -- §102(e) -- §102(f) -- §102(g) -- §102 Special Forms -- Obviousness /Nonobviousness (§103) -- §103(a) -- Manner of Invention -- Graham v. John Deere: Fundamental Inquiry -- Prima Facie Obviousness -- Prima Facie Requirements -- §102(e), (f), and (g) Events as §103 Prior Art -- Admission as Prior Art under §103 -- Rights and Procedures under the Patent Cooperative Treaty (PCT) -- Definitions -- Strategies -- PCT Process -- PCT Application -- Significant §102(e) Issues -- Pre-AIPA (Filed November 29, 2000 or Earlier) -- Post-AIPA (Filed November 29, 2000 or Later) -- Chapter 3 -- Online Patentability Search -- Introduction -- Anatomy of a Patent -- Patentability Search Online -- Patent Office Resources -- The U.S. Patent and Trademark Office -- Keyword Selection and Searching -- Patent Images -- Published Application Search -- Patent Classification Search -- Searching with Classification -- Patent Classification Example -- Searching the Gazette -- The European Patent Office -- The World Intellectual Property Organization -- Canadian Patent Office -- Internet Search Engines -- Technical Databases -- Patent Searches and IP Services -- Patent Copies and Search Facilities -- Chapter 4 -- Online Filing Basics -- Introduction -- USPTO -- Obtain a Customer Number -- Associate Customer Number with Patent Application(s) -- Request a Digital Certificate -- Obtain Access Codes -- Set Up the Software -- WIPO -- PCT-EASY Registration -- PCT-EASY Installation -- PCT-SAFE -- EPO -- Chapter 5 -- USPTO EFS Overview -- EFS Purpose -- EFS Software Overview -- What EFS Supports -- What EFS Does Not Support -- Basic Steps to Using EFS -- Getting Started -- Word Processing and Imaging Programs -- File Preparation -- Obtain Specification Authoring Tools -- Obtain Submission Software -- Obtain PTO Direct Security™ -- Technical Issues -- Setup -- EFS Software on Multiple Computers -- Use of EFS Software on a Network -- File Management -- Web Browser -- Operational Issues -- General -- Specification Authoring -- Figures, Drawings, Chemical Structures, and Mathematical Equations -- Additional Application Data -- View /Print -- Transmitting to the USPTO -- Receipt of Filing -- Fees /Payment -- Troubleshooting /Errors -- Chapter 6 -- USPTO EFS Scenarios -- Introduction -- Terminology -- Patent Application Publication Process and EFS Submissions -- New Utility Application -- The Applicant -- The USPTO -- Preparation for Authoring -- Specification -- Viewing -- Submission Folder -- Submission -- Notes -- EFS Filing Scenario with Compact Disc -- The Applicant -- The USPTO -- New Utility Application with Assignment -- Provisional Application -- 18-Month Publication -- The Applicant -- The USPTO -- Voluntary Pre-Grant Publication -- Amended Publication as First Pre-Grant Publication by the USPTO -- Redacted Publication Submission as First Pre-Grant Publication -- by the USPTO -- Redacted Publication Submission after Initial Publication -- Corrected Publication Due to Error -- Computer Readable Format Biotechnology Sequence Listing -- for Pending Paper Application -- Filing an Assignment Recordation for a Previously Filed Patent -- Application Using EFS -- Application Data Sheet -- Case Study for a New Utility Application -- Overview -- Background -- Preparation for Authoring the Patent Application Specification Document -- Authoring the Patent Application Specification Document -- Creating Necessary Transmittals and the Cover Sheet -- Tracking Down the Application -- Chapter 7 -- USPTO: PASAT -- Introduction -- Getting Started -- Creating New Specifications -- Importing Specifications -- Loading Specifications -- Interface Features -- Menus and Menu Options -- Toolbars -- Shortcut Keys -- Office Assistant -- Status Bar -- Disabled Microsoft Word Features -- Editing Specifications -- Changing Tag and Entity Display -- Using the Specification Map -- Managing Selections -- Managing Paragraphs -- Adding Paragraphs -- Splitting Paragraphs -- Deleting Paragraphs -- Renumbering Paragraphs -- Managing Claims -- Adding Claims -- Adding Claim-Text Elements -- Indenting Claim-Text Elements -- Splitting Claim-Text Elements -- Deleting Claim-Text Elements -- Splitting Claims -- Deleting Claims -- Renumbering Claims -- Managing Claim Dependencies -- Creating Claim Dependency References -- Redefining Reference Targets -- Deleting Claim Dependency References -- Formatting Text -- Copy, Cut, and Paste -- Paste Paragraphs -- Paste Claims -- Removing Double Emphasis Tags -- Nonbreaking Spaces and Hyphens -- Smart Quotes, Apostrophes, Fractions, and Double Hyphens -- Reversing Operations -- Managing Complex Work Units -- Converting Equations, Formulae, Symbols, and Tables -- to TIFF Images -- Changing the Browser Display Font -- Managing Tables -- Managing Figures -- Adding Figures -- Reordering Figures -- Removing Figures -- Managing Special Characters -- Inserting Custom Characters -- Replacing Unknown Symbols -- Deleting Special Characters -- Entering Biological Deposit Data -- Spell Check -- Spell Check in Real-Time -- Spell Check in Batch Mode -- Finding and Replacing Content -- Validating and Previewing Specifications -- Validate Specification -- Previewing Specifications -- Saving and Exporting Specifications -- Saving Specifications -- Exporting Specifications -- Chapter 8 -- USPTO TSA -- Introduction -- Macro Setup -- Template Setup Procedures -- Overview of WordPerfect XML Template -- The Template Environment -- EFS Toolbars -- Keyboard Shortcuts -- Overview of EFS Tagging -- The Display Codes View -- Copy and Paste from Text Files -- Paste and Tag Paragraphs -- Insert Special Characters -- Methods of Tagging -- Resolving Tagging Errors -- Correcting a Text Insertion Error -- Correcting a Missing Tag Error -- Correcting an Attribute Error -- Using Undo to Correct an Error -- Using Redo to Correct an Error -- Authoring a Specification -- Create a New Specification -- Select Specification Sections -- Add MPEP Recommended Section -- Remove MPEP Recommended Section -- Create a New Section -- Title of Invention (Required) -- Cross-Reference to Related Applications (Optional) -- Continuity Data -- Referenced Applications and Patents -- Copyright Statement (Optional) -- Federal Research Statement (Optional) -- Compact Disc Appendix (Optional) -- Background of Invention (Optional) -- Summary of the Invention (Optional) -- Brief Description of the Drawings (Conditional) -- Brief Description of Sequences (Conditional) -- Detailed Description of the Invention (Required) -- Deposit of Computer Program Listings (Optional) -- What Is Claimed (Required) -- Basic Claim Tagging -- Additional Claims -- Indented Sections -- Dependent Claim Reference -- Display Claims -- Abstract of the Disclosure (Required) -- Figures (Optional) -- Preparation for Attaching Figures -- Attaching Figures -- Formatting Images -

    Out of stock

    £109.25

  • Practical Pharmaceutical Laboratory Automation

    Taylor & Francis Inc Practical Pharmaceutical Laboratory Automation

    1 in stock

    Book SynopsisLaboratory automation is an increasingly important part of the job description of many laboratory scientists. Although many laboratory scientists understand the methods and principles involved in automation, most lack the necessary engineering and programming skills needed to successfully automate or interface equipment in the lab. A step-by-step, how-to reference and guide, Practical Pharmaceutical Laboratory Automation explores the processes needed to automate the majority of tasks required in research today. The author discusses topics ranging from automated mathematical analysis to robotic automation of chemical processes, to combinations of these and other processes. He presents a detailed discussion of high throughput screening and assay development and takes an in-depth look at Visual Basic as the primary programming language used in laboratories. The text has a dedicated web site (http://www.pharmalabauto.com) that contains all the sample code and examples contained witTable of ContentsIntroduction. Microsoft Excel Visual Basic Macros Running VBA Macros in Excel. Advanced Microsoft Excel VB Macro Techniques. Robotic Automation Using Visual Basic. Low Level Hardware Interfacing Using VB. Electronics for Automation. Robust Data Analysis Using Origin Lab's Origin. Agilent (HP) Chemstation Macro Writing. Appendices.

    1 in stock

    £166.25

  • Cutaneous TCell Lymphoma

    Taylor & Francis Inc Cutaneous TCell Lymphoma

    Out of stock

    Book SynopsisCutaneous T-cell lymphoma (CTCL) is a general term for many lymphomas of the skin including mycosis Fungoides and Sezary syndrome. This book presents the state of the art in CTCL epidemiology, clinical features, pathology, immunochemistry, diagnostic molecular techniques, staging and prognosis, and treatment. Edited by one of the leading experts in the disease, Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sezary Syndrome provides comprehensive coverage of the disease and presents techniques for diagnosis and state-of-the-art treatment modalities, such as ultraviolet light, steroids, and topical chemotherapeutics.Table of ContentsCutaneous T-cell lymphoma (CTCL) is a general term for many lymphomas of the skin including mycosis Fungoides and Sezary syndrome. This book presents the state of the art in CTCL epidemiology, clinical features, pathology, immunochemistry, diagnostic molecular techniques, staging and prognosis, and treatment. Edited by one of the leading experts in the disease, Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sezary Syndrome provides comprehensive coverage of the disease and presents techniques for diagnosis and state-of-the-art treatment modalities, such as ultraviolet light, steroids, and topical chemotherapeutics.

    Out of stock

    £161.50

  • Transpersonal Hypnosis

    Taylor & Francis Transpersonal Hypnosis

    1 in stock

    Book SynopsisTranspersonal Hypnosis presents a multidimensional, energy-based view of human awareness that integrates disparate biological, psychological, and spiritual therapeutic techniques. Each of the chapters - all from world-renowned contributors - includes both a historical overview and the theory behind the development of each technique. The authors emphasize experimental studies that examine the validity of using hypnotically accessed transpersonal states of consciousness to heal the body, mind, and spirit. Several clinical vignettes highlight the types of medical and psychological symptoms responsive to these approaches. The emerging field of spiritually-influenced treatments is transforming the practice of medicine.Trade Review"Transpersonal Hypnosis explores an ancient yet modern view of the mind-that it extends beyond the body and is free in space and time. Modern physicians, therapists, and scholars are at long last beginning to take seriously this view of consciousness. The implications of this perspective for our origins and destiny are full of hope and promise, as this book compellingly reveals."-Larry Dossey, M.D., Editor, Alternative Therapies in Health and Medicine"A wonderful collection of information and insights that are vital to our understanding of the nature of life, healing and consciousness."-Bernie Siegel, M.D."The new frontier is on these pages; this is where the intellectual excitement, the creativity, and the healing potential truly lies. Bravo!"-Belleruth Naparstek, author of "Your Sixth Sense" "Overall, this is a highly recommended book that is clearly written and provides helpful information for anyone interested in transpersonal growth in clinical practice, from novice to experienced professionals. I was pleased to pick up new insights, new techniques, and new suggestions for further reading from many of the chapters." - Daniel J. Benor, MD, author of "Healing Research, Volumes I-IV"Table of ContentsIntroduction Chapter Overviews and Authors' Biographies Fear of Psychic Phenomena-Charles Tart, Ph.D. Mesmerism, Hypnosis and the Human Energy Field-Eric Leskowitz, MD Energy Healing and Hypnosis-Eric Leskowitz, MD Clinical Intuition and Energy Field Resonance-John Tatum, MD Hypnosis, Yoga and Psychotherapy-Susana Hassan-Schwarz Galle, Ph.D. Yogic Breathwork and Ultradian Hypnosis-Darlene Osowiec Ph.D. Animal Imagery and the Personal Totem Pole Process-Stephen Gallegos, Ph.D. Ericksonian Hypnosis and Meditation-Stephen Wolinsky, Ph.D. Jungian Past Life Regression-Roger Woolger, Ph.D. Prenatal and Perinatal Hypnotherapy-David Chamberlain, Ph.D. Spirit Releasement Therapy-Joseph Wicker, Psy.D. Cross-Cultural Perspectives on Transpersonal Hypnosis-Stanley Krippner, Ph.D. Channelling and Hypnosis-Eric Leskowitz, MD

    1 in stock

    £66.49

  • CRC Desk Reference on Sports Nutrition

    Taylor & Francis Inc CRC Desk Reference on Sports Nutrition

    1 in stock

    Book SynopsisThe landscape of sports nutrition is dramatically altering, as those in search of optimal performance are moving the field from haphazard alchemy to exact science. Currently, thousands of products -- from ancient herbs and old standards to hormone extractions and test tube concoctions --compete for a place at the training table of both professional and amateur competitors, as well as those non-athletes seeking some potent elixir of youth. Unfortunately, getting straight and genuinely relevant information on these products can be a time consuming and frustrating challenge.The CRC Desk Reference on Sports Nutrition following in the tradition of authoritative CRC references, will place in your hands the most comprehensive desk reference available on sports nutrition products.Intelligently organized, each entry, depending upon its prominence and importance, is followed either by a definition, paragraph, essay, composition, article, or feature article. Many of the more complTable of ContentsAlphabetical by topic. Sample topics include, Acetylcholine, Aerobic Exercice, Alanine Cycle, Amylose, Anorexia, Anaerobic Threshold, Basal Metabolic Rate, Body Mass Index, Bulimia Nervosa, Caffeine, Carbohydrate, Cholesterol, Chromium, Coenzyme Q. Creatinine, Dehydration, Diabetes Mellitus, Dietary Supplements, Eating Disorders, Fiber, Glucose Polymer, Glycolysis, Heat Exhaustion, Incomplete Protein, Hypertension, Immune System, Iron Deficiency Anemia, Lysine, Macronutrient, Metabolic Rate, Obesity, Ovovegetarian, Pesticides, Retinol, Saturated Fatty Acids, Sport Nutrition, Trace Minerals, Vegetarian, Water Soluble Vitamins, and Zinc, to name just a few.

    1 in stock

    £166.25

  • Angiogenesis

    Taylor & Francis Inc Angiogenesis

    1 in stock

    Book SynopsisWhy a new book on angiogenesis and why now? For the first time concepts proposed over 30 years ago have found clinical validation. In the last two years the first antiangiogenic agents have been approved by the FDA for the treatment of cancer and age-related macular degeneration. Not surprisingly, this clinical success has raised a new set of basic and clinical questions that need to be addressed. Angiogenesis: From Basic Science to Clinical Applications presents the latest advances in basic science and reviews the status of the clinical applications of angiogenic growth factors and inhibitors. It explores current molecular and genetic findings on the regulation of angiogenesis, discusses the results of clinical trials and identifies the pathological conditions that are most likely to benefit from such treatments. Edited by a leading researcher in the field, the book includes contributions from multiple experts in their respective disciplines, supplemented by illustratioTable of ContentsVascular Endothelial Growth Factor: Pathophysiology and Clinical Implications. Signal Transduction of VEGF Receptors toward Angiogenesis. Growth Factors and Lymphangiogenesis. Notch and Vascular Development. Neural Guidance Molecules in Vascular Development. Neuropilins, Receptors for the VEGF and Semaphorin Families, Link Angiogenesis and Axon Guidance. Non-Angiogenic Functions of VEGF. Contribution of Pro-Angiogenic Hematopoietic Cells to Vascularization of Tumor and Ischemic Tissue. Selected Antiangiogenic Drugs as Potentially Effective Universal Chemosensitizers. Using an Anti-VEGF Monoclonal Antibody to Treat Cancer. Ocular Neovascularization. Targeting VEGF for Neovascular Age-Related Macular Degeneration and Macular Edema. Therapeutic Angiogenesis for Cardiovascular Disease.

    1 in stock

    £204.25

  • Chronic Pain 2 Pain Management

    Taylor & Francis Inc Chronic Pain 2 Pain Management

    1 in stock

    Book SynopsisProviding a general approach to the understanding and management of all forms of chronic pain, this book offers a clear and reader-friendly format that clarifies procedures in the diagnosis, assessment, and treatment of the most common chronic non-cancer pain entities. Describing various types of intractable non-cancer pain, including neuropathic, somatic, and visceral pain, this source discusses the many available types of treatments, including opioid and adjunctive pain medications, and the safe and proper use of narcotics for treating chronic pain.Table of ContentsAnatomy and Physiology of Pain: The Central and Peripheral Nervous Systems. Molecular Mechanisms of Nociception. Peripheral Mechanisms of Chronic Non-Cancer Pain. The Myofascial Pain Syndrome. Sympathetic Aspects of Soft Tissue Pain. Medical Management of Myofascial Pain. Evidence Based Medicine: Basics. Trigger Point Injections. Fibromyalgia: Clinical Aspects and Pathophysiology. Fibromyalgia: Clinical Evaluation and Medical Management. Soft Tissue Pain Syndromes: Brain, Mind and Body Connections. Neuropathic Pain. Tension-Type Headache. Medications. Narcotic Therapy for Patients with Chronic Non-Cancer Pain. Psychological Aspects of Chronic Non-Cancer Pain. Interventional Pain Medicine in the Treatment of Chronic. Non-Cancer Pain. Interdisciplinary Treatment of Chronic Non-Cancer Pain

    1 in stock

    £152.00

  • Practical Aspects of Hyaluronan Based Medical

    Taylor & Francis Inc Practical Aspects of Hyaluronan Based Medical

    1 in stock

    Book SynopsisThe ballooning body of research devoted to hyaluronan (HA) reflects its enormous potential for various medical applications. There have been many successes of varying degrees in the development of medical products based on HA, but also some setbacks. While there is obviously ample information available on the chemistry and various properties of this macromolecule, Practical Aspects of Hyaluronan Based Medical Products is the first book devoted to systematically applying this knowledge to product development.Based on the author''s extensive experience working with HA, this book explores in detail the chemistry, composition, formulation, testing, safety, effectiveness, quality control, and regulatory approval of HA medical products. It begins with a survey of the historical development and recent products based on hyaluronan. Subsequent chapters detail the rheological properties of the molecule and explore the chemical principles and methods forming the technical basis of productTable of ContentsOverview. Chemistry. Rheological Properties of Hyaluronan as Related to Its Structure, Size, and Concentration. Standards, Tests, and Analytical Methods. Safety of Hyaluronan-Based Medical Products in Their Indicated Applications. Clinical Performance, Mechanism of Action, and Product Characteristics. Index.

    1 in stock

    £209.00

  • Radiotracers in Drug Development

    Taylor & Francis Inc Radiotracers in Drug Development

    Out of stock

    Book SynopsisAlthough there are numerous books on drug metabolism, Radiotracers in Drug Development is unique in explaining how radiotracers are used to elucidate a drugâs absorption, distribution, metabolism, and excretion (ADME). Covering traditional and recent technologies and applications, the book takes a strong industrial approach, discussing the basics of scintillation counting and untangling the various data processing methods often specific to individual manufacturers.The chapters include descriptions of the latest micro-plate counters and the growing applications of accelerator mass spectrometry, positron emission tomography, gamma-scintigraphy, and radioluminography. In addition to describing how the analytical technologies work, the contributors explain how the data are interpreted and used in the drug registration process. A unique reference and training aid essential for every drug metabolism department or drug metabolism research team, the book provides insighTable of ContentsRadiotracers and Drug Registration. Radioactivity and Radiotracers. The Study of Drug Metabolism Using Radiotracers. DNA Binding, Isotope Dilution, and Other Uses of Radiotracers. Quantitative Whole-Body Autoradiography (QWBA). Scintillation Counting. Statistics in Liquid Scintillation Counting. Instrumentation for Detection of Radioactivity. Sample Preparation for Liquid Scintillation Counting. Biomedical Accelerator Mass Spectrometry. Positron Emission Tomography. Gamma Scintigraphy and SPECT.

    Out of stock

    £237.50

  • Cardiovascular Molecular Imaging

    Taylor & Francis Inc Cardiovascular Molecular Imaging

    Out of stock

    Book SynopsisCardiovascular Molecular Imaging is based on a groundbreaking NIH symposium sponsored by the American Society of Nuclear Cardiology. The first all-inclusive guide to the targeted molecular imaging of the cardiovascular system, it includes color illustrations throughout and is packaged with a user-friendly CD-ROM with supplemental material.This reference covers new methods for the analysis and management of cardiovascular pathophysiological processes and discusses new technologies for analyzing cardiovascular receptors, gene expression, vascular structures, and biological processes that affect the heart and associated vessels.Bridging the gap between basic science and clinical applications, the contributors: Span the most recent molecular imaging procedures used to stage disease states and assess treatment outcomes for specific cardiovascular ailments Table of Contents Imaging of Myocardial Metabolism. PET/Micropet Imaging. SPECT/Microspect Imaging. CT/Microct Imaging. Targeted MRI. Targeted Echocardiography. Combined Systems. Intravascular Radiation Detectors. Intravascular Ultrasound. Optical Coherence Tomography (OCT). Overview of Imaging of Cardiac Reporter Genes. PET Imaging of Transcriptional Regulation. In-Vivo Imaging of Transgene Expression Using the Herpesviral Thymidine Kinase Reporter Gene. Optical Cardiovascular Imaging. Overview of Targeted Radiochemistry. Radiotracer Development for Evaluating the CV System. Bispecifc Antibodies and Poly-Linkage Methods. Small Animal Anesthesia and Physiological Monitoring. PET Radiotracers for Imaging of Transgenic Murine Models. Application of Radiotracers In Small Animals. Overview of Imaging Atherosclerosis. Potential Targets for Imaging of Atherosclerosis. Radiotracer Imaging of Unstable Plaque. Atherosclerosis Imaging with Nanoparticles. Overview of Angiogenesis. Radiolabeled Imaging of Myocardial Angiogenesis. Echocardiographic Targeted Imaging of Angiogenesis. MR Imaging of Angiogenesis. PET Imaging of Neurocardiac and Adrenergic Receptors. Imaging of Beta-Receptors in Heart. SPECT Imaging of Cardiac Adrenergic Receptors. Radiotracer Imaging Of Myocardial Inflammation. Echocardiographic Imaging of Myocardial Inflammation. Myocardial Imaging Labeling Mmps and Hormone Receptor Ligands. Imaging Apoptosis and Imaging Cardiac Growth. Imaging Cardiac Growth. Molecular Signals of Metabolism. PET Imaging of Metabolism. SPECT Imaging of Metabolism. MRS Imaging of Metabolism. Future of Cardiovascular Molecular Imaging

    Out of stock

    £256.50

  • Amyloid and Amyloidosis

    Taylor & Francis Inc Amyloid and Amyloidosis

    1 in stock

    Book SynopsisThis authoritative volume contains 179 chapters by international experts on recent developments in our understanding of amyloid proteins, protein folding disorders, and new and proposed clinical trials in amyloidosis. Topics include detection and characterization techniques; biological functions; genetics; disorders, diagnosis, and treatments, including organ transplants and drug therapies; results from extensive clinical studies; and epidemiology. This is a valuable resource for clinicians who care for patients with systemic and localized forms of amyloidosis, and for researchers in biochemistry, neurobiology, and cell biology.Table of ContentsAmyloid Fibrillogenesis: AL Amyloidosis. AA Amyloidosis. Familial Amyloidosis. Central Nervous System Amyloidosis. Localized Amyloidosis. Therapeutics. Satellite Symposium, Neurochem Inc.

    1 in stock

    £228.00

  • Immunotoxicology and Immunopharmacology

    Taylor & Francis Inc Immunotoxicology and Immunopharmacology

    1 in stock

    Book SynopsisContinuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health. For the first time in the book's history, an entire section covers the phylogeny and ontogeny of the immune system, spanning levels of biological complexity from earthworms to marine mammals.Table of ContentsImmunotoxicology and Hazard Identification. Immunopharmacology and Immunotoxicology of Therapeutics. Environmental Agents. Immunotoxicology in the Lung. Developmental Immunotoxicity. Wildlife Immunotoxicology. Autoimmunity and Autoimmune Diseases. Neuroimmunology. Allergy and Hypersensitivity.

    1 in stock

    £166.25

  • Brain Aging Models Methods and Mechanisms

    Taylor & Francis Inc Brain Aging Models Methods and Mechanisms

    Out of stock

    Book SynopsisRecognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur, new possibilities emerge for limiting the effects of aging on neural function. A single source reference is necessary to keep abreast of the recent advances and future directions of gerontology research. Brain Aging: Models, Methods, and Mechanisms offers a selective overview of the research in this rapidly expanding field. A valuable resource for new and established investigators of the aging brain, this volume reviews critical studies of brain aging in new animal models, as well as advances in brain imaging techniques that permit investigations in aging humans with increasingly higher resolution. DetaileTable of ContentsAssessing Cognitive Aging, Quantifying Aging-Related Changes in the Brain, Assessing Functional Changes in the Aging Nervous System, Mechanisms Contributing to Brain Aging, Index

    Out of stock

    £166.25

  • Pharmaceutical Product Development Vol165 In

    Taylor & Francis Inc Pharmaceutical Product Development Vol165 In

    1 in stock

    Book SynopsisDuring the last two decades, the pharmaceutical industry has been under pressure to reduce development costs and the time needed to bring drugs to market in order to maximize return on investment and bring treatments to patients sooner. To meet these ends, pharmaceutical scientists working in the differing areas of pharmacy, pharmaceutics, and pharmacokinetics are collaborating to address physicochemical and biological issues in the early stages of development to avoid problems in later stages. In Vitro-In Vivo Correlation (IVIVC) is a multidisciplinary tool that has been successfully applied in testing the effectiveness of a drug substance. The only comprehensive guide available on IVIVC, this source illustrates the emerging importance of IVIVC in the drug development process, and covers the most recent advances and regulatory perspectives on the role of IVIVC in the pharmaceutical industry.Table of ContentsIntroduction. Dissolution: Fundamentals of In Vitro Drug Release and Biopharmaceutics Classification System (BCS). Pharmacokinetics: Basics of Drug Absorption from a Biopharmaceutical Perspective. IVIVC Models: Development and Validation. Computational Approaches to Develop IVIVC Models. IVIVC - Pharmaceutical Drug/Product Development. Role of IVIVC in the Early Phases of Drug Discovery and Drug Delivery Technology Development. IVIVC - Setting Dissolution Specifications. IVIVC - Oral Drug Delivery: Immediate Release and Extended Release Dosage Forms. In Vitro-In Vivo Correlation for Modified Release Parenteral Drug Delivery Systems. IVIVC - Transdermal and Other Novel/Special Drug Delivery Systems. Regulatory Perspective. Regulatory Guidance on IVIVC: Across the World

    1 in stock

    £166.25

  • Cosmetic Formulation of Skin Care Products

    CRC Press Cosmetic Formulation of Skin Care Products

    1 in stock

    Book SynopsisSpecifically written to meet the needs of the cosmetic chemist and engineer, this reference outlines the latest technologies and issues pertinent to the development novel skin care products including advances in formulation and development, raw materials and active ingredients, compound testing, and clinical assessment. Organized by product category, then by body application area, this guide supplies all one needs to know to create effective skin care products for men and women in a diverse range of ethnic populations.Table of ContentsCosmetic Formulations of Skin Care Products. Cutaneous Formulation Issues. Formulation for Special Populations. Personal Cleansing Products: Properties and Use. Toners and Astringents. The Dry Skin Cycle. Factors Influencing Optimal Skin Care and Product Selection. Antiperspirants. Photoprotection and the Prevention of Photocarcinogenesis. Anti-Aging Skin Care Formulations. The Role of Cosmeceuticals in Dermatology. Skin Lightening Agents. Medical and Surgical Approaches to Skin Lightening. Topical Exfoliation - Clinical Effects and Formulating Considerations. Over the Counter Acne Medications. Topical Botanicals. Herbs in Cosmeceuticals: Are They Safe and Effective? Topical Anti-Inflammatories. Topical Nutritional Antioxidants. What is Next in Skin Care Cosmetic Products?

    1 in stock

    £170.00

  • Retinoids and Carotenoids in Dermatology

    Taylor & Francis Inc Retinoids and Carotenoids in Dermatology

    1 in stock

    Book SynopsisThis up-to-date reference describes how retinoids and carotenoids function in the skin and how they can be utilized to prevent and treat a wide variety of skin diseases, as well as advance biomedical research in relation to cancer treatment and immunology. Providing an in-depth update on the pharmacology, pharmacodynamics, and new applications of retinoid therapy, this source also addresses topics outside of dermatology, such as vitamin A nutrition, and the role of antioxidants in aging, metabolic activation, and cellular signaling. With chapters by internationally recognized authorities in specialties ranging from biochemistry and nutrition to molecular biology and clinical science, this source will stand as the only up-to-date source on the topic.Trade Review”…an excellent comprehensive reference on virtually all the effects, functions, and therapeutic applications of retinoids and skin…I would highly recommend it for all dermatologists since everyone uses retinoids in their practice…This is the best book I have read on the complexity of retinoids and their immunologic powers on the skin. Readers have to be prepared to spend time studying it, but they will be well rewarded.” Doody’s RevewTable of ContentsFrom Carotenoids and Vitamin A to Retinoids. Animal Models for Retinoid Receptor Research. Retinoids and the Skin. Recent Studies on the Pharmacokinetics and Metabolism of Retinoids in the Skin. Anti-Aging Effects of Retinoids and Mechanisms of Action. Retinoid Therapy of Acne and Sebocyte-Related Disorders. Retinoids and Retinoic Acid Blocking Agents in Psoriasis. Retinoid Treatment of the Disorders of Cornfication. Oral Retinoid Therapy in Children and Infants. Retinoids in Cutaneous T-Cell Lymphomas. Retinoid Therapy and Autoimmune Skin Disease. Retinoids in the Prevention and Treatment of Skin Cancer. Side-Effects and Pitfalls in Retinoid Therapy. Retinoid-Induced Hyperlipidemia and the Risk of Atherosclerosis. Carotenoids and the Skin. Antioxidative Effects of Carotenoids. Beta-Carotene in the Treatment of Skin Disorders. Caroteinoids as Cancer Preventive Agents. Beta-Carotene in Erythropoietic Protoporphyria.

    1 in stock

    £209.00

  • Complications of Urologic Surgery and Practice

    Taylor & Francis Inc Complications of Urologic Surgery and Practice

    1 in stock

    Book SynopsisDivided into five sections focusing on perioperative, surgical, pediatric, endoscopic and laparoscopic, and miscellaneous complications, this guide supplies state-of-the-art strategies for the identification, prevention, and management of the myriad complications that can arise during urologic surgical treatment. With contributors from leading health centers across the United States, this source reviews the potential complications of the latest laparoscopic procedures, as well as those related to systemic conditions.Table of ContentsPERIOPERATIVE COMPLICATIONS. Infectious Complications. Cardiovascular Issues. Metabolic Complications. Neurologic Complications. Anesthesia. Nutritional Considerations. OPEN SURGICAL COMPLICATIONS. Complications of Open Renal Surgery. Complications of Adrenal Surgery. Complications of Radical Retropubic Prostatectomy. Modern Complication of Radical Perineal Prostatectomy. Complications of Open Prostate Surgery. Complications of Urethral Stricture Surgery. Complications of Radical Cystectomy. Complications of Urinary Diversions. Complications of Retroperitoneal Lymphadenectomy. Complications of Renal Transplantation. Complications of Genitourinary Trauma. Management of the Surgical Complications of Penile Carcinoma. Complications of Benign Adult Penile and Scrotal Surgery. Complications of Female Incontinence Surgery. PEDIATRIC SURGICAL COMPLICATIONS. Complications of Orchiopexy. Complications of Hypospadias Surgery. Complications of Antireflux Surgery. Complications of Exstrophy and Epispadias Surgery. COMPLICATIONS OF ENDOSCOPIC AND LAPAROSCOPIC SURGERY. Complications of Shock Wave Lithotripsy. Complications of Percutaneous Lithotripsy. Complications of Laparoscopic Adrenal Surgery. Complications of Laparoscopic Radical Prostatectomy. Complications of Robotic Prostatectomy. Complications of Transurethral Surgery. Complications of Minimally Invasive Treatments for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasis. Complications of Minimally Invasive Renal Surgery. Complicarions in Ureteroscopy. MISCELLANEOUS COMPLICATIONS. Complications of Intravesical Therapy. Complications of Penile Injection. Complications of External Beam Radiation Therapy. Complications of Prostate Brachytherapy. Complications of Chemotherapy for Urologic Cancer. Complications of Immunotherapy. Vascular Complications of Urologic Surgery.

    1 in stock

    £228.00

  • Chronic Rhinosinusitis

    Taylor & Francis Inc Chronic Rhinosinusitis

    Out of stock

    Book SynopsisRhinosinusitis is increasing in prevalence and incidence, and has been estimated to affect approximately 31 million patients in the United States each year. This comprehensive reference offers recommendations for the optimal treatment of chronic rhinosinusitis and indicates pathways for new research in the field. Offering an interdisciplinary approach to the topic, edited by an allergist and an otolaryngologist, this source discusses advances in the understanding of the pathophysiology of the diseases, as well as important diagnostic tools for the assessment of chronic rhinosinusitis. It also summarizes published studies of chronic rhinosinusitis management for evidence-based medical care.Table of ContentsClinical Patterns of Illness and Disease Classification. Impact of CRS on QOL and Medical Expenditure. Environmental and Allergic Factors; Experimental Models. Innate & Acquired Immunity and Epithelial Cell Function. Role of T Cells and Eosinophils in CRS. Role of Mast Cells and Basophils in CRS. Mucociliary Transport in CRS. Glandular and Vascular Abnormalities in CRS. Bacterial Infection and Antibiotic Treatment in CRS. Bacteria as Immune Stimulant in CRS. Fungi as Immune Stimulant EFRS. Radiologic Assessment of CRS Including Image Guided Technology. Role of Rhinoscopic Assessment in Medical Management. Role of Steroids in Treatment of RS +/- Polyposis. Ancillary Therapies in CRS. Classic AFS Including Clinical Trials. Medical Management of RS Comorbidities. Special Considerations Regarding Pediatric CRS. Approach to Evaluation and Medical Management of CRS. Interfacing Medical Surgical Management of CRS

    Out of stock

    £49.39

  • Thrombus and Stroke

    Taylor & Francis Inc Thrombus and Stroke

    Out of stock

    Book SynopsisProviding a clear foundation as to what a clot is, how it forms, and the most recent approaches to treatment, Thrombus and Stroke is an all-inclusive resource covering: The fundamental science of clot formation and the pharmacokinetics of thrombolysis The clinical impact of thrombus as it pertains to stroke and the most recent clinical and minimallyinvasive approaches to this disorder Current pharmacological interventions and the latest findings on neurovascular disease Clinical management of stroke Thrombogenicity of vascular implants In vivo stroke modeling Methods to assess the efficacy of anticoagulation therapy From the latest imaging techniques to endovascular treatments, this comprehensive, advanced volume provides critical data needed for diagnosis and treatment. The valuable information will assist physicians in the prevention of future strokes and complTable of Contents1. Thrombus Formation. 2. Blood Flow and Thrombus Formation. 3. In vivo Experimental Models of Focal Ischemic Stroke. 4. Assessment and Management of Vascular Implant Thrombogenicity. 5. Stroke IMaging (CT, MR, SPECT, PET). 6. Pharmacology and Clot: Immediate and Chronic Interventions. 7. Acute Ischemic Stroke: Endovascular Revascularization and Reperfusion. 8. The Future of Neuroprotection. 9. Acute Ischemic Stroke: Paradigm for Treatment.

    Out of stock

    £46.54

  • Handbook of Human Toxicology

    Taylor & Francis Inc Handbook of Human Toxicology

    Out of stock

    Book SynopsisCovering some of the most important topics in modern toxicology, the Handbook of Human Toxicology is a unique and valuable addition to the current literature. It addresses issues, answers questions, and provides data related to. Within each of these five major sections are several carefully selected topics that reflect the current state of human toxicology. From tissue uptake of mercury to the effects of drugs on immune systems, the text provides much-needed information quickly and easily.Table of ContentsPart 1: Metals Toxicology, Chapter 1. Methods of Metals Toxicology, Chapter 2. Occupational and Environmental Exposures, Chapter 3. Metal Metabolism and Toxicities, Chapter 4. Cellular and Molecular Mechanisms o f Metal Toxicities, Chapter 5. Tissue Uptake and Subcellular Distribution of Mercury, Part 2: Nutrition and Toxicology, Chapter 6. Using Food Consumption Data to Determine Exposure to Toxins, Chapter 7. Nutrition, Pharmacology, and Toxicology: A Dialectic, Chapter 8. Toxic Agents, Chemosensory Function, and Diet, Chapter 9. Essential and Nonessential Mineral Interactions, Chapter 10. Naturally Occurring Orally Active Dietary Carcinogens, Part 3: Inhalation Toxicology, Chapter 11. Structure and Function of the Respiratory Tract, Chapter 12. Disposition of Inhaled Toxicants, Chapter 13. Respiratory Responses to Inhaled Toxicants, Chapter 14. Methods in Human Inhalation Toxicology, Part 4: Immunotoxicology, Chapter 15. Introduction, Chapter 16. Immunotoxicology Methods, Chapter 17. Immunotoxicology of Therapeutic Proteins, Chapter 18. Effects of Drugs on Immune System Parameters, Chapter 19. Metal Immunotoxicology, Chapter 20. Effects of Pesticides and Organic Solvents on Immune System Parameter, Part 5: Reproductive and Developmental Toxicology, Chapter 21. Biology of Reproduction and Methods in Assessing Reproductive and Developmental Toxicity in Humans, Chapter 22. Male Reproductive Toxicity, Chapter 23. Female Reproductive Toxicity, Chapter 24. Developmental Toxicity, Index

    Out of stock

    £175.75

  • Unexplained Fever

    Taylor & Francis Inc Unexplained Fever

    Out of stock

    Book SynopsisThis book covers pathophysiology of fever, the general approach to the febrile patient, and offers a systematic, in-depth discussion regarding the differential diagnosis of unexplained fever. The authors define an unexplained fever as a fever which lasts a minimum of 14 days and whose etiology is not known. This one-of-a-kind publication highlights the main causes of fever, specifically infectious diseases, cancer, connective tissue diseases, various rare disorders, plus etiologies which are often ignored. Also, laboratory and medical imaging techniques for diagnosing fevers are included. Written in a comprehensive, unrepetitious style, this must-have resource includes such aspects as the history of the fever, a review of published cases, the approach to the patient, and an analytical review. This up-to-date volume is an indispensable guide that should be read by physicians, surgeons, internists, microbiologists and other medical professionals.Table of ContentsPart I GENERAL ASPECTS OF FEVER, Chapter 1 Introduction — Definition of Unexplained Fever, History of Fever, Statistical Data, Classification, Chapter 2 The Anatomy and Physiology of Normal Thermoregulation, Chapter 3 Pathophysiology of Fever, Chapter 4 Thermometry, Chapter 5 Approach to the Febrile Patient, Part II UNEXPLAINED FEVER ASSOCIATED WITH DISEASES OF ORGAN SYSTEMS, Chapter 6 Fever in Diseases of the Cardiovascular System, Chapter 7 Fever in Respiratory Diseases, Chapter 8 Unexplained Fever Associated with Diseases of the Gastrointestinal Tract, Chapter 9 Diseases of the Hepatobiliary Tree and Pancreas Associated with Fever, Chapter 10 Unexplained Fever in Neurological Disorders, Chapter 11 Unexplained Fever Associated with Musculoskeletal Disorders, Chapter 12 Unexplained Fever in Hematologic Disorders: Section 1 — Benign Hematologic Disorders, Chapter 13 Unexplained Fever in Hematologic Disorders: Section 2 — Malignant Hematologic Disorders, Chapter 14 Fever in Endocrinologie Disorders, Chapter 15 Fever in Inherited and Metabolic Disorders, Chapter 16 Unexplained Fever Associated with Cutaneous Manifestations, Part III ENVIRONMENTAL AND BIOLOGIC CAUSES OF UNEXPLAINED FEVER, Chapter 17 Iatrogenic and Occupational Fever, Chapter 18 Unexplained Fever Associated with Hypersensitivity and Auto-immune Diseases, Chapter 19 Unexplained Fever in Infectious Diseases: Section 1 — Viruses, Chlamydia, Mycoplasma, Rickettsiae, Higher Bacteria, Cell-Wall Deficient Bacteria, and Fungi, Chapter 20 Unexplained Fever in Infectious Diseases: Section 2 — Commonly Encountered Aerobic, Facultative Anaerobic, and Strict Anaerobic Bacteria, Spirochetes, and Parasites, Chapter 21 Unexplained Fever in the Immunocompromised Patient, Chapter 22 Unexplained Fever in Patients Returning from the Tropics Including U.F. Associated with Hypereosinophilia, Chapter 23 Fever in Oncology, Chapter 24 Fever of Unexplained Origin — Psychiatric Aspects, Chapter 25 Miscellaneous Causes of Unexplained Fever, Part IV UNEXPLAINED FEVER IN SURGERY, Chapter 26 Surgical Aspects of Fever, Chapter 27 Unexplained Fever in Urology, Chapter 28 Unexplained Fever in Gynecology, Chapter 29 Unexplained Fever in Obstetrics, Part V UNEXPLAINED FEVER AT DIFFERENT AGES, Chapter 30 Unexplained Fever in the Pediatric Age Group, Chapter 31 Unexplained Fever in Geriatrics, Part VI DIAGNOSTIC PROCEDURES AND MANAGEMENT OF UNEXPLAINED FEVER, Chapter 32 Laboratory Diagnostic Tests in the Evaluation of Fever, Chapter 33 System Imaging in Unexplained Fever, Chapter 34 Treatment, INDEX

    Out of stock

    £142.50

  • Methods for Skin Absorption

    Taylor & Francis Inc Methods for Skin Absorption

    Out of stock

    Book SynopsisThis up-to-date volume describes the wide variety of available methods concerning percutaneous absorption of drugs and toxins. It discusses in detail the advantages and disadvantages of each method. This unique publication provides a clear, systematic presentation of each aspect which must be considered when designing and performing skin penetration experiments and when interpreting results. It includes specific information regarding necessary supplies and equipment, along with commercial sources for these items. This state-of-the-art book is an ideal instructional manual for investigators uninitiated in performing percutaneous absorption and metabolism studies. Those involved with investigative dermatology, dermatological research, toxicology, and pharmacology will find this reference interesting and indispensable.Table of ContentsChoice of Membranes for In Vitro Skin Uptake Studies and General Experimental Techniques. Penetrant Characteristics Influencing Skin Absorption. Instrumentation and Methodology for In Vitro Skin Diffusion Cells. Preparation of Biological Membranes. Methodology for the Execution of In Vitro Skin Penetration Determinations. In-Vivo Methods for Determining Percutaneous Absorption and Metabolism of Xenobiotics: Indirect Methods. Physical Resources Needed for In Vivo Animal Studies. Detection Methods. Data Interpretation and Analysis in Percutaneous Absorption Studies. Specialized Techniques: Congenitally Athymic (Nude) Animal Models. Specialized Technique: The Isolated Perfused Porcine Skin Flap (IPPSF). Validity of Skin Absorption and Metabolism Studies.

    Out of stock

    £85.49

  • The Immunologic Revolution

    Taylor & Francis Inc The Immunologic Revolution

    Out of stock

    Book SynopsisThis unique volume contains reviews by some of the most prominent immunologists in the world. The authors present vital facts for each of their areas of expertise and provide individual perspectives on how their own contributions were developed and how these contributions influenced general immunological thinking and development. This impressive collection of personal reviews by these internationally renowned immunologists makes The Immunologic Revolution an important and lasting contribution to the entire biomedical community.Table of ContentsThe Precipitin Reaction, Microbial Agglutination, Complement Fixation, and Relations Between Chemical Structure and Antigen/Antibody Interaction (M. Heidelberger). Darwin and Pasteur and Causal Realism (D.W. Talmage). From Transimmunology to the Present Paradigm (A.F. Bussard). Looking Back on the Induction Phase of the Immune Response (J. Sterzl). Tolerance as a Regulatory Process-Communication in the Immune System and Between Immunologists (B. Cinader). What Happened to Tolerance? (E. Diener). One Cell-One Antibody: Impact on Immunological Theory and Practice (G.J.V. Nossal). Reflections on the Lymphomyeloid Complex (J.M. Yoffey). The Minnesota Scene: A Crucial Portal of Entry to Modern Cellular Immunology (R.A. Good). Immunological Function of the Thymus and Thymus-Derived Cells (J.F.A.P. Miller). T Cell-B Cell Collaboration (H.N. Claman). Will the Real Antigen-Presenting Cell Please Stand Up? (M. Richter). Immunity and the Sisyphus Effect (H. Friedman). Adventures in Cellular and Humoral Immunology (A.B. Stavitsky). Antigenicity of Antibodies (F. Milgrom). On the Threshold of the Door of No Admittance (J.G. Sinkovics). Concepts of Delayed Type Hypersensitivity-Historical Aspects with Special Regard to the '60s (G. Gillissen). Remembrances of Things Past by a Participating Witness (Z. Ovary). Innovating in Immunology. Tissue Anaphylactic Sensitiziation, Immunosuppressive Processes and Antibody Producing Cell Multipotentiality (P. Liacopoulos). Tumor Immunology-Personal Peregrinations and Perspectives (D.W. Weiss). The Macrophage in Immunobiology: Explorations of Terra Incognita (K. Stern). The Immune-Neuroendocrine Circuitry-A Generation of Progress (A. Szentivanyi). Thyroid Autoimmunity: A Voyage of Discovery (N.R. Rose).

    Out of stock

    £161.50

  • Thyroid Diseases

    Taylor & Francis Inc Thyroid Diseases

    1 in stock

    Book SynopsisThyroid Diseases: Clinical Fundamentals and Therapy provides a wide-ranging examination of all clinically significant areas of thyroid diseases. Underlying physiological principles are closely linked to the clinical situation and practical therapeutic interventions. The book examines the clinical course, therapy, and final outcome of thyroid diseases, particularly the bimodal and transient evolution of several thyroid diseases. It also discusses the medical, surgical, and radiometabolic therapy of thyroid diseases, stressing the pros and cons of each therapeutic modality. More than 80 acknowledged experts from North America, Europe, and Japan have contributed to this exceptional reference volume, making it essential for physiologists, clinical endocrinologists, radiologists, researchers in nuclear medicine, oncologists, and radiotherapists.Table of ContentsClassification: Classification of Thyroid Diseases (F. Monaco). Euthyroidism: Diffuse and Multinodular Nontoxic Goiter (J.T. Dunn). Hyperthyroidism: Diffuse Toxic Goiter (Basedow-Flajani-Graves' Disease) (S. Nagataki, H. Tamai, and S. Yamashita). Toxic Nodular Goiter (J. Orgiazzi and R. Mornex). Unusual Forms of Thyrotoxicosis (S. Mariotti, E. Macchia, and A. Pinchera). Iodine-Induced Thyrotoxicosis (L. Chiovato, P. Vitti, and A. Pinchera). Transient Hyperthyroidism (G. Napolitano and F. Monaco). TSH-Secreting Pituitary Adenomas (P. Beck-Peccoz and G. Faglia). Thyroid Crisis (F. Monaco and M.A. Satta). Hypothyroidism: Congenital Hypothyroidism and Screening (T.P. Foley, Jr). Adult Acquired Hypothyroidism (A. Ermans). Biosynthetic Defects in Thyroid Hormonogenesis (G. Medeiros-Neto). Pituitary and Hypothalmic Hypothyroidism (G. Faglia and P. Beck-Peccoz). Subclinical and Transient Hypothyroidism (M. D'Armiento). Hypothyroid Coma (F. Monaco and M.A. Satta). Resistance to Thyroid Hormones: Syndromes of Resistance to Thyroid Hormone (C.A. Meier and B.D. Weintraub). Thyroiditis: Acute Suppurative Thyroiditis (M. Centanni, S. Sciacchitano, and M. Andreoli). Subacute (De Quervain's) Thyroiditis (N. Amino and K. Takada). Chronic Thyroiditis (M. Izumi). Postpartum and Silent Thyroiditis (N. Amino). Tumors: The Thyroid Nodule (S.G. Jackson and L. Wartofsky). Differentiated Thyroid Carcinoma (A.J. Van Herle and A.J. Lutz). Anaplastic Thyroid Carcinoma (M. Schlumberger). Medullary Thyroid Carcinoma (M. Schlumberger, P. Gardet, and C. Parmentier). Ophthalmopathy: Graves' Ophthalmopathy: Diagnosis, Pathogenesis, Prognosis, Treatment (R. Mornex and J. Orgiazzi). Therapy: Medical Therapy (F. Monaco). Surgery in the Management of Thyroid Diseases (N.W. Thompson). Metabolic Radiotherapy of Thyroid Disease: General Principles (B. Shapiro and L. Troncone). The Metabolically Directed Radiotherapy of Hyperthyroidism with Radioiodine (B. Shapiro and L. Troncone). The Metabolically Directe

    1 in stock

    £546.25

  • Transformation of Human Diploid Fibroblasts

    Taylor & Francis Inc Transformation of Human Diploid Fibroblasts

    1 in stock

    Book SynopsisThis comprehensive publication draws together the important aspects of carcinogen-cell interaction. This interesting work describes the regulation of normal cell proliferation, cellular responses to carcinogen damage, the biologic consequences of cellular DNA modification, the structural and genomic changes resulting from carcinogen insult, and the possible involvement of such changes in the conversion of normal human fibroblasts to malignant cells. It presents current reviews with up-to-date literature references and provides critical information from leading investigators that is essential in understanding the biology of human cell transformation. This volume is especially useful to advanced students in genetic toxicology, molecular biologists, and all who are interested in the molecular and macromolecular changes in human cells leading to neoplasia.Table of ContentsPreface. Variations in Susceptibility to Initiation of Carcinogenesis During the Cell Cycle. Cell Cycle Regulation of DNA Repair Enzymes and Pathways. DNA Repair and Poly(ADP-ribose) Synthesis in Human Fibroblasts and Other Cell Types. Repair of O-Alkylation Damage in Human Cells. Ultraviolet Radiation-Induced Transformation of Human Cells. Biological Characterization and Quantitation of Markers of Transformation of Human Fibroblasts. Mechanisms for Cell Transformation and Carcinogenesis by Genotoxic and Nongenotoxic Agents: Role of Sodium Saccharin. Relationship Between Bulky Carcinogen-DNA Modification: Carcinogenesis and Mutagenesis. Metabolism of Polyaromatic Hydrocarbons by Human Fibroblasts. DNA Adducts and Human Cell Transformation. Cytotoxicity and Cell Culture. Mechanisms by Which Phorbol Ester Tumor Promoters Affect Gene Expression in Human Cells. Changes in Gene Expression Associated with Neoplastic Transformation of Human Fibroblasts: The Abundant Cellular Proteins. Differential Repair of Damage in Specific DNA Sequences of Human Cells. Index.

    1 in stock

    £285.00

  • Innovative Leukemia and Lymphoma Therapy

    Taylor & Francis Inc Innovative Leukemia and Lymphoma Therapy

    1 in stock

    Book SynopsisInnovative Leukemia and Lymphoma Therapy provides a complete and up-to-date overview of the exciting new treatment modalities in leukemia and lymphoma that are being introduced in the clinic today. Written by international experts in the field, this volume examines clinical studies on topics such as: tyrosine kinase inhibitors, histon deacetylase inhibitors, and farnesyl transferase inhibitors radioimmunotherapy, gene-directed therapy, and immunotherapy by vaccination monoclonal antibodies anti-angiogenesis approaches Within each chapter, this well-illustrated, comprehensive source provides a summary of the rationale for treatment, the pathways that are involved, and the translational research to students, scientists, and clinicians. In addition, this book focuses on the concerns of conventional but novel anticancer agents, modulation of classical multidrug resistance, and modulators of single agent drug r

    1 in stock

    £133.00

  • Ulcer Disease

    Taylor & Francis Inc Ulcer Disease

    1 in stock

    Book SynopsisThe latest data on the pathogenesis of ulcer disease is presented in this text, with the emphasis that an understanding of the pathogenesis and etiology of ulcer diseases represents the most rational approach to pharmacology - the prevention and treatment of ulcer disease. Early and late biochemical and functional changes, morphologic stages of the injury and healing phases, as well as vascular factors in ulceration are highlighted. In addition, new pathogenetic elements on neuroendocrine and other endogenous modulators and circadian rhythms in ulcerogenesis are covered. The section on new pharmacology consists of several chapters presenting new animal models of gastric, small intestinal and colonic ulcers because in vivo models represent the basis to test and accurately detect new antiulcer drugs. A large series of chapters cover new drugs for ulcer prevention and treatment. This book is indispensible to investigators in basic and applied research, academic and industrial pharmacTable of ContentsPATHOGENESIS. EARLY AND LATE BIOCHEMICAL AND FUNCTIONAL CHANGES. Mechanisms of Gastrointestinal Damage by Non-Steroidal Anti-inflammatory Drugs. Correlations Between Free Radicals and Membrane-Dependent Energy Systems in Ethanol-Induced Gastric Mucosal Damage in Rats. Gastric Motility and Overall Blood Flow During Cold Restraint in the Rat. Enzymic Aspects of Cysteamine-Induced Duodenal Ulcers with Special Reference to Bicarbonate Secretion. Cysteamine is a Potent Inhibitor of Duodenal Phosphoprotein Phosphatase in Rats: Probable Role of Gastric Acid Hypersecretion. MORPHOLOGIC STAGES OF THE INJURY AND HEALING PHASES. Mechanisms of Rapid Epithelial Restitution of the Superficial Rat Gastric Mucosa after Ethanol Injury. Microscopic Analysis of Ischemic Gastric Injury in the Rat. Effects of Ulcerogens and Other Conditions on Gastric Epithelial Proliferation. Gastric Mucosal Barriers and the Actions of Aspirin. Early Cytologic Precursors to Cysteamine-Induced Duodenal Ulcer in Rats. VASCULAR FACTORS IN ULCERATION. Vascular Factors in Gastric Mucosal Injury. The Role of Microvasculature in Acute Gastric Mucosal Damage and Protection. Gastric Mucosal Microvascular Architecture and Mucosal Blood Flow in Rats During Stress. Role of Acid and Tissue Prostaglandins in the Production of Gastric Mucosal Damage. Critical Mucosal Oxygenation Level and Promotion by Acid and Histamine of Hemorrhagic Shock-Induced Gastric Ulcer in Rats. CENTRAL AND PERIPHERAL NEUROENDOCRINE INFLUENCES. Central Nervous System Action of Neuropeptides to Influence or Prevent Experimental Gastroduodenal Ulceration. Neural Influences on Gastroduodenal HCO3 Secretion. Involvement of Dopamine and Dopamine Receptors in Stress Gastric Ulceration. Somatostatin and Gastrin Secretion from the Isolated Perfused Rat Stomach: Neural and Hormonal Regulation and the Effect of the Ulcerogen, Cysteamine. Possible Involvement of Central Mechanisms in Antiulcer and Antisecretory Actions of Prostaglandins. CIRCADIAN RHYT

    1 in stock

    £441.00

  • Human Saliva Volume I

    CRC Press Human Saliva Volume I

    Out of stock

    Book SynopsisThis book covers current knowledge of the origins of various salivary compounds, their normal values, age dependency, relation to flow rate, diseases or hormonal status, and assay problems regarding human saliva. It discusses practical aspects of salivary analyses.Table of Contents1. Practical Aspects of Salivary Analyses 2. Salivary Secretion Rate, Buffer Capacity, and pH 3. Salivary Electrolytes 4. Salivary Glycoproteins 5. Statherin and the Acidic Proline-Rich Proteins 6. Salivary Histidine-Rich Proteins 7. Genetic Protein Polymorphisms of Human Saliva

    Out of stock

    £275.50

  • Metabolism of AnabolicAndrogenic Steroids

    Taylor & Francis Inc Metabolism of AnabolicAndrogenic Steroids

    1 in stock

    Book SynopsisThis book presents an authoritative review of the research regarding the influences of anabolic-androgenic steroids on metabolism. The book provides a concise description of the biochemistry of these steroids using simple terms and includes methods of separation and their clinical applications. The first section of the book examines the general structure, nomenclature, and classification of anabolic-androgenic steroids. Subsequent chapters explore concepts basic to understanding the pathways of their metabolism in both target and non-target tissues, including the interactions of steroids with receptors and the effects of steroids on the cellular metabolism of skeletal muscle. The changes and molecular base of modifications in metabolism during exercise involving anabolic-androgenic steroids are also described. Finally, a comprehensive review of methods for scanning and identifying anabolic-androgenic steroids in biological fluids is presented, as well as a discussion regarding the appTable of ContentsAnabolic-Androgenic Steroids (AAS): Structure, Nomenclature, Classification, and AAS Biological Properties. Extracellular Androgen Binding Proteins. AAS Intracellular Reception. Translocation of Cytoplasmic Hormone-Receptor Complexes to Cellular Nucleus. Molecular Mechanisms of AAS Action. Enzymic Systems Participating in AAS Metabolism. Role of AAS in Metabolism Regulation in Norm and Pathology and use in Medicine and Cattle Breeding. AAS Radioimmunoassay. Chromatographic Methods of AAS Determination. References. Conclusion. Index.

    1 in stock

    £475.00

  • Chemical Contaminants in Human Milk

    Taylor & Francis Inc Chemical Contaminants in Human Milk

    1 in stock

    Book SynopsisChemical Contaminants in Human Milk contains a comprehensive, up-to-date global review of the contamination of human milk with environmental and occupational chemicals. The book covers many different aspects of this problem, including the extent and benefits of breast-feeding, the transfer of chemicals into breast milk, analytical methodologies used in human milk studies, the levels of chemical contaminants in human milk, and geographical variations and time trends in levels. The many different factors that can influence the levels of contaminants in breast milk are also discussed. Other important topics examined include human milk contamination due to exposure of the mother at the workplace and the risk to her baby, the intake of toxic chemicals by breast-fed infants, calculated intakes and official limit values, the toxicological implications of human milk contamination based on available data from animal experiments and human studies. The book concludes with an overall assessment oTable of ContentsPreface. List of Chemical Names and Abbreviations. EXTENT AND BENEFITS OF BREAST-FEEDING. TRANSFER OF CHEMICAL CONTAMINANTS INTO HUMAN MILK. DESIGN OF HUMAN MILK STUDIES. ANALYTICAL METHODS FOR MAJOR CHEMICAL CONTAMINANTS IN HUMAN MILK. LEVELS AND TRENDS OF ENVIRONMENTAL CHEMICALS IN HUMAN MILK. FACTORS AFFECTING THE LEVELS OF RESIDUES IN HUMAN MILK. OCCUPATIONAL CHEMICALS IN HUMAN MILK. ASSESSMENT OF INFANT INTAKES OF CHEMICALS VIA BREAST MILK. TOXICOLOGICAL IMPLICATIONS OF PERSISTENT ORGANOHALOGENS IN MOTHER'S MILK AS INDICATED BY ANIMAL EXPERIMENTS. TOXICOLOGICAL IMPLICATION OF HUMAN MILK RESIDUES AS INDICATED BY TOXICOLOGICAL AND EPIDEMIOLOGICAL STUDIES. OVERALL ASSESSMENT AND EVALUATION.

    1 in stock

    £332.50

  • Iron Transport and Storage

    Taylor & Francis Inc Iron Transport and Storage

    1 in stock

    Book SynopsisThe objective of this book is to review and summarize recent developments in our understanding of iron transport and storage in living systems. It includes an overview of the evolutionary aspects of iron metabolism and bacterial iron transport, as well as a detailed discussion of molecules with specific roles in iron metabolism in higher organisms. It also presents relationships between intracellular iron metabolism and cell proliferation. Iron Transport and Storage addresses the comparative aspects of iron transport and storage in different tissues. This essential volume is very useful for hematologists, physical and biological chemists, cell and molecular biologists, physiologists, and clinicians with an interest in the biology and metabolism of iron.Table of ContentsIRON IN BIOORGANIC EVOLUTION. An Introduction to the Nature of Iron Transport and Storage. Iron-Dependent Enzymes in Mammalian Systems. Parallels in the Mode of Regulation of Iron Assimilation in All Living Species. Iron and Oxygen: A Dangerous Mixture. STRUCTURE OF PROTEINS OF IRON STORAGE AND TRANSPORT. Transferrin and Lactoferrin. Ferritin. MOLECULAR BIOLOGY OF PROTEINS OF IRON TRANSPORT AND STORAGE. Molecular Biology of the Transferrins. Molecular Analysis of the Transferrin Receptor and Its Gene. Ferritin Gene Structure and Expression. ROLE OF IRON AND PROTEINS OF IRON METABOLISM IN CELL PROLIFERATION AND MALIGNANCY. Iron-Transferrin Requirements and Transferrin Receptor Expression in Proliferating Cells. Ribonucleotide Reductase. Ferritin in Malignant Cells. IRON METABOLISM IN SPECIFIC TISSUES. Comparative Aspects of Iron Transport and Storage in Different Tissues. Developmental Changes in Iron Storage (the Ferritins) and Iron Transport (the Transferrins and Transferrin Receptors). Intestinal Iron Metabolism and Absorption. Erythroid Cell Iron Metabolism and Heme Synthesis. Iron Metabolism in the Reticuloendothelial System. Modulation of the Availability of Intracellular Iron. Iron and Proteins of Iron Metabolism in the Central Nervous System.

    1 in stock

    £333.00

  • Prostaglandin Inhibitors in Tumor Immunology and

    Taylor & Francis Inc Prostaglandin Inhibitors in Tumor Immunology and

    1 in stock

    Book SynopsisThis book provides an updated overview of eicosanoid metabolism. It also presents a timely discussion of eicosanoid metabolism in the process of tumor cell metastasis, in chemoprotection and radioprotection associated with cancer therapy, and in cell differentiation. The book focuses on the role of eicosanoids in the immunology of malignant disease. This includes how various immune cell populations in cancer are affected by the secretion and action of various eicosanoids and metabolites of eicosanoids and how these processes may be affected by various pharmacological manipulations and interventions to augment anti-tumor immunity. Head and neck cancer is covered in great detail to illustrate a cancer in humans where these considerations are particularly relevant. This important volume demonstrates that the principal factor in cancer patient immunologic deficiency is related to excess secretion by monocytes of prostaglandins.Table of ContentsCyclooxygenase and Lipoxygenase Pathways of Arachidonic Acid Metabolism (W.L. Smith and O. Laneuville). Participation of Lipoxygenase Products in Lymphohematopoietic and Other Cell Proliferation and Differentiation (K.M. Anderson, M. Wiederhold, and F. Ondrey). Eicosanoids and Tumor Cell Metastasis (D.G. Tang and K.V. Honn). The Impact of Prostaglandins on Cancer Patient Immunity (D.P. Braun and J.E. Harris). Prostaglandins and Host Immune Response in Squamous Cell Carcinoma of the Head and Neck (D.S. Cross, F. Ondrey, S.K. Juhn, and G.L. Adams). Eicosanoid-Induced Radioprotection and Chemoprevention of Normal Tissue During Cancer Treatment (W.R. Hanson). Prostaglandins and the Host Immune System: Application of Prostaglandin Inhibitors for Cancer Immunotherapy (P.K. Lala and M.-N. Saarloos).

    1 in stock

    £333.00

  • Pulmonary Surfactant

    Taylor & Francis Inc Pulmonary Surfactant

    1 in stock

    Book SynopsisThis book represents a comprehensive update on pulmonary surfactant by merging classical knowledge with new information. Topics include surfactant secretion and alveolar processing and recycling; physical bases and different theoretical models of the physiological mechanism for pulmonary surfactant action; recent findings on surfactant-like material in other organs; developmental processes and multifactorial regulation; etiology and physiopathology of neonatal respiratory distress; and modern methods for functional explorations of the lung in neonates and experimental models in animals. The book also contains a discussion on the management of hyaline membrane disease, from both the experimental and clinical points of view.Table of ContentsChapter 1 Pulmonary Surfactant — An Overview, Chapter 2 The Type II Pneumocyte, Chapter 3 Nature, Function, and Biosynthesis of Surfactant Lipids, Chapter 4 Structure, Function, and Regulation of Pulmonary Surfactant Proteins, Chapter 5 The Biology of the Surfactant-Associated Proteins, Chapter 6 Comparative Aspects of Pulmonary Surfactant, Chapter 7 Secretion, Alveolar Processing, and Turnover of Pulmonary Surfactant, Chapter 8 Physiological Mechanisms for the Action of Pulmonary Surfactant, Chapter 9 Role of Surfactant in Other Organs, Chapter 10 Developmental Aspects of the Alveolar Epithelium and the Pulmonary Surfactant System, Chapter 11 Fibroblast Pneumonocyte Factor, Chapter 12 Etiology of Neonatal Respiratory Distress Syndrome and the Assessment of Lung Maturity, Chapter 13 Functional Exploration of the Lung in Neonatal Respiratory Distress Syndrome. Use of Animal Models for the Study of Respiratory Distress, Chapter 14 Exogenous Surfactant in the Management of Hyaline Membrane Disease, Index

    1 in stock

    £333.00

  • Functional Neuroimaging

    Taylor & Francis Inc Functional Neuroimaging

    Out of stock

    Book SynopsisThe first text designed specifically with clinical practitioners in mind, Functional Neuroimaging demonstrates the clinical application and utilization of functional neuroradiology for early diagnosis, neurological decision-making, and assessing response to cancer therapy. Edited by the Founding President of American Society of Functional Neuroradiology, this guide expertly describes the incorporation of this technology into clinical practice and showcases high-quality color images depicting the function and mechanisms of the brain.Features: Helps clinicians incorporate functional neuroradiology into their practice Shows new advancements in functional brain imaging to benefit the diagnosis, management, and treatment of patients Depicts current methods for imaging the central nervous system, as well as cutting-edge approaches for the imaging of brain function Contains 320 intricate, full-color figures comprising the anatomTrade Review"There are 29 authors and 18 chapters in this 352-page book, and, although a major emphasis is placed on cortical activation (what many primarily think of when functional imaging is mentioned), the latter half of the book is concerned with diffusion imaging and its derivatives, perfusion images and the metrics derived from such studies, and magnetoencephalography." "The book is written for the clinical neuroradiologist, and, aside from some scary-looking formulas and mathematics in the perfusion chapter, the book holds true to that promise." "In summary, this book is a winner and puts the current state of clinical functional neuroimaging under 1 cover....Functional Neuroimaging is highly recommended to all practicing neuroradiologists and trainees in neuroradiology fellowship programs." (American Society of Neuroradiology, 2008) Table of ContentsBLOOD OXYGEN LEVEL DEPENDANT FUNCTIONAL MRI (BOLD FMRI). A Historical Perspective on Functional Neuroimaging. Physical Principles of Bold fMRI – What Is Important for the Clinician. Preparing the Patient for the fMRI Study. Optimization of Paradigm Selection and Delivery. Methods of Analysis. Fact or Artifact? Language. Vision, Memory and Higher Cortical Function. Cortical Plasticity. Functional Image Guided Neurosurgery. Developmental Disorders. Neurodegenerative Disorders. DIFFUSION IMAGING. Diffusion Imaging and Tensor Physics for the Clinician. Diffusion Weighted Imaging in Stroke. Diffusion Imaging in Brain Tumors and Treatment Response. DTI of Developmental and Pediatric Disorders. DTI of Neurodegenerative Disorders. DTI and Diffusion Tractography in Brain Tumor Patients. PERFUSION IMAGING. Physical Principles. MR Perfusion Imaging of Tumors and Related Conditions. MAGNETOENCEPHALOGRAPHY (MEG). Principles. Brain Tumors. Seizure Disorders. CLINICAL MOLECULAR IMAGING AND EMERGING NEUROIMAGING APPLICATIONS. Pharmaceutical Agents for Molecular Imaging. In Vivo Tracking of Stem Cells in the CNS (MR, Optical). Monitoring Neuroregeneration and Cell Repair (PET, MR, Optical). Other Experimental Therapeutics. Immunoimaging in the Brain (PET Reporter Technology)

    Out of stock

    £228.00

  • Geriatric Diabetes

    Taylor & Francis Inc Geriatric Diabetes

    Out of stock

    Book SynopsisThe number of elderly patients with diabetes is increasing at a significant rate. Responding to this growth, this source serves as a solid arsenal of information on the varying presentations and challenges associated with diabetes in the geriatric patient, and supplies clearly written sections on the screening, diagnosis, and treatment of diabetes in elderly populations. With contributions from renowned authorities from the national and international institutions, this reference will depict the role of specific co-morbidities, socioeconomic aspects, and caregiver issues on the effective management of diabetes in the older adult.Table of ContentsIntroduction. Epidemiology. Biology of Aging and Glucose Homeostasis. Pathophysiology and Insulin Resistance. Pharmacokinetics and Pharmacodynamics. Screening and Diagnosis of Diabetes in Older Adults. Co-Morbidities in Older Adults with Diabetes. Hypertension. Lipid Disorders. Cognitive Dysfunction. Depression. Falls and Diabetes. Polypharmacy. Urinary Incontinence. Chronic Pain Syndrome. Erectile Dysfunction. Functional Disabilities. Complications of Diabetes in Older Adults. Care of Older Hospitalized Patients. Cardiovascular and Cerebrovascular Complications. Peripheral Vascular Diseases. Nephropathy. Neuropathy. Eye Complications. Foot Care in Diabetes. Dermatological Complications. Hypoglycemia. Multidisciplinary Management of Diabetes in Older Adults. Goal Setting in Older Adults. Oral Agents. insulin. Medical Nutrition Therapy. Exercise. Diabetes Education in Older Adults. Monitoring. Risk Factor Management. Special Populations of Older Adults with Diabetes. Community Living Older Adults of Different Ethnicity. Management of Diabetes in Transitional Care Facilities. Management of Diabetes in Assisted Care and Nursing Home. Socio-Economic Aspects and Caregiver Issues. Economic Considerations. Community Support Services. Caregiver and Family Issues. Promising Research. Stem Cell Research. Pancreatic Transplantation. New Pharmacotherapy and Technologies.

    Out of stock

    £152.00

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