Medicine / Healthcare: general issues / topics Books

Book SynopsisThis compendium brings together articles from the ''Journal of Alternative Medicine Research'' in 2009 with a broad research agenda on a global basis, addressing questions ranging from policy to practice, human development and a whole spectrum of issues also involving infancy and early childhood, to adolescence and adulthood. The information presented in this book is intended to generate new knowledge, link research to practice and policy, and help build networks of research collaborations and move science forward in this field.

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Book SynopsisThis continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed include sexual dimorphism in corticosteroid signalling; hepatic encephalopathy; guidelines for the collection and submission of necropsy samples; functions of dietary valine; challenges in vaccination against mastitis and hepatocyte cytotoxic activity and it physiological and pathological relevance.

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Book SynopsisThe Patient Protection and Affordable Care Act (PPACA) authorises new funding for numerous existing discretionary grants and other programs and activities. PPACA also creates a number of new discretionary grant programs and activities and provides for each an authorisation of appropriations. Funding for all of these programs and activities is subject to action by congressional appropriators. This book summarises all discretionary spending provisions in PPACA that authorise appropriations for grant programs and other activities.

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Book SynopsisFederal regulations generally start with an act of Congress, and are the means by which statutes are implemented and many specific requirements are established. The Patient Protection and Affordable Care Act is a particularly noteworthy example of congressional delegation of rulemaking authority to federal agencies. This book identifies more than 40 provisions in PPACA that require, permit, or contemplate rulemaking by federal agencies to implement the legislation.

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Book SynopsisThis continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed include abscisic acid-inducible genes during salinity and drought stress; medical device related infections; the effect of opiates on pregnancy and breastfeeding; using primate models to study vaginal HIV infection; the biosynthesis of ABA in fruits; patellar tendonitis in dancers; and metabolism and health.

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Book SynopsisPropolis is a natural product, collected by honeybees Apis mellifera, from various plant sources. Honeybees use it for the construction and repair of their hive as well as for defence purposes. Propolis has gained popularity in alternative medicine. It is extensively used as a popular remedy in foods and beverages. This book presents the chemical composition and biological activities of propolis from different regions of the globe.

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Book SynopsisPropolis is a natural product, collected by honeybees Apis mellifera, from various plant sources. Honeybees use it for the construction and repair of their hive as well as for defence purposes. Propolis has gained popularity in alternative medicine. It is extensively used as a popular remedy in foods and beverages. The purpose of this book is to present readers with an integrated view on molecular mechanisms of beneficial effects of propolis in acute and chronic humans. This book will provide current and comprehensive information on the protective effects of propolis on human health and treatment chronic human diseases.

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Book SynopsisThis continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed include the effect of aroma massage on constipation in advanced cancer patients; the histamine role in cell migration and matrix remodelling; neuronal histamine circuits as modulators of cognitive processes in the brain; cationic cell penetrating peptides mediating hemodynamic changes through mast cell activation; lipid emulsions for intoxications with membrane stabilising agents; the pathomechanics and management of perilunate dislocations; and robotic arm-assisted orthopaedic knee arthroplasty.

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Book SynopsisThis continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed include adenoviruses; molecular mechanisms in allergic rhinitis; potential genetic factors in emphysema; magnesium homeostasis; disorders of fibrinogen and the cause and treatment of eclampsia.

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Book SynopsisThis continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed include the adverse effects on reproduction of corticotropin; the actions of morphine and its related substances on primary-afferent neurons; magnetic resonance spectroscopy of bile in the diagnosis of chronic cholestatic diseases; cold-active enzymes and their potential use in biotechnology; midwifery practice and the classification and differential diagnosis of sclerosing cholangitis.

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Book SynopsisThis book compiles biographical sketches of top professionals in the field of medicine, as well as research summaries from a number of different focuses in this important field.

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Book SynopsisMedicaid is a means-tested entitlement program that finances the delivery of primary and acute medical services as well as long-term services and supports. Medicaid is a federal and state partnership that is jointly financed by both the federal government and the states. The federal government''s share for most Medicaid expenditures is called the federal medical assistance percentage (FMAP) rate. Generally determined annually, the FMAP formula is designed so that the federal government pays a larger portion of Medicaid costs in states with lower per capita incomes relative to the national average (and vice versa for states with higher per capita income). Federal Medicaid funding to states is open-ended. The federal government provides states a good deal of flexibility in determining the composition of the state share (also referred to as the non-federal share) of Medicaid expenditures. As a result, there is significant variation from state to state in the funding sources used to finance the state share of Medicaid expenditures. This book provides an overview of Medicaid''s financing structure, including both federal and state financing issues. The Medicaid expenditures section of the book discusses economic factors affecting Medicaid, state variability in spending, and projected program spending. Other issues that are examined include congressional proposals to turn Medicaid into a block grant program, federal deficit reduction proposals affecting Medicaid, and state fiscal conditions affecting Medicaid financing and services.

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Book SynopsisThe health care reform debate in the United States raises many complex issues including those of coverage, accessibility, cost, accountability, and quality of health care. Underlying these policy considerations are issues regarding the status of health care as a constitutional or legal right. This book series analyses the constitutional and legal issues pertaining to the right of health care and the power of Congress to enact and fund health care programs. Other topics discussed in this volume include the U.S. mental health delivery system infrastructure; a review of fluoridation and regulation issues in drinking water; the number, role, and ownership of pharmacy services administrative organisations; strategies used by adults to reduce their prescription drug costs; supply and access to generalist and speciality physicians; trends in potentially preventable hospital admissions among adults and children; medicaid disproportionate share hospital payments; and medicare, medicaid and other health provisions in the American Taxpayer Relief Act of 2012.

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Book SynopsisThis continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include a review on the optimisation of the formulations of metronidazole through a different administration route; the use of metronidazole in cancer gene therapy and targeted cell ablation; protective roles of glutathione peroxidases in diabetes; stem cell disorders and bone marrow transplantation; catalase gene mutant mice; what animal models of inflammatory arthritis teach us about bone damage; methylprednisolone use in autoimmune diseases; the clinical use of methylprednisolone in oncology; how pretreatment with methylprednisolone reduces adverse clinical effects of inflammatory response induced by heart surgery and cardiopulmonary bypass; and the potential side effects of methylprednisolone.

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Book SynopsisThe United States, like all countries, faces many threats with the potential for large-scale health consequences, including disease outbreaks, natural disasters, and terrorist attacks. Preparing for and responding to these and other threats requires the commitment of, and co-operation among, all segments of society: government, the private sector, local communities, and international partners. This book presents the Nation''s first National Health Security Strategy (NHSS), and Implementation Plan, which is intended to help galvanise efforts to minimise the health consequences associated with significant health incidents. The NHSS was developed in consultation with a broad range of stakeholders, including representatives from local, state, territorial, tribal, and federal government; community-based organisations; private-sector firms; and academia. The vision for health security described in the NHSS is built on a foundation of community resilience -- healthy individuals, families, and communities with access to health care and with the knowledge and resources to know what to do to care for themselves and others in both routine and emergency situations. Communities help build resilience by implementing policies and practices to ensure the conditions under which people can be healthy, by assuring access to medical care, building social cohesion, supporting healthy behaviours, and creating a culture of preparedness in which bystander response to emergencies is not the exception but the norm. Securing our Nation''s health is a formidable task and must be a responsibility that is broadly shared among virtually all segments of society.

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Book SynopsisThis continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this book include microbiological hazards associated with infant formula; spontaneous bacterial peritonitis; rheumatoid arthritis; chronic subdural hematomas; metabolic acidosis; ankle joints; haemorrhagic shock; hematoma enlargement; thoracic hematoma; peritoneal dialysis; renal tubular acidosis; metabolic diseases; and lactic acidosis in HIV-infected patients.

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Book SynopsisFirearms injuries are considered to be a "privilege" of treatment by military surgeons. It is difficult to find one book that includes all of the knowledge about injuries of the locomotor system caused by firearms, and the treatments of these injuries. This book presents the author''s experience in treating more than 5,000 wounded people in the last war in Bosnia and Herzegovina. Authentic images of injuries by firearms and the results of treatment are provided for better understanding of the wounds. The key to success in the treatment of these injuries is the primary surgical treatment of wounds. This includes "sterilising wounds", stabilising of broken bone with or without bone defect, treatment of nerves, and blood vessels and open joints. As a measure for stabilisation of open fractures, an external fixator was used for over 85% in the war in former Yugoslavia. The Author presents in detail his vast experience in treatment of open fractures, peace or war trauma of skin, fat, muscle, bone and open joints. He uses a clear indication of treatment in order to reach complete recovery, or a lesser degree of invalidity. He gives a detailed presentation of when and which methods of treatments should be used to treat bone defects, osteomyelitis, delayed healing, pseudoarthrosis and open joints. The Author shows that he achieves a positive clinical outcome, shorter hospital stay and reduced treatment by using these techniques and methods. This book provides instructions on how to treat the most complex open fractures of the locomotor system as to prevent complications and speed up rehabilitation, which is the most valuable to surgeons and should be available in every hospital, at any time, especially when we have in mind the global fight against terrorism.

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Book SynopsisThis continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this book include taxonomy for mechanical ventilation; a current update on avian pathogenic Escherichia coli; tularemia; the important of early diagnosis of figurate erythemas and paraneoplastic syndromes; non-invasive mechanical ventilation; the diversity, antimicrobial resistance and the role in human disease of coagulase-negative staphylococci; and vaccine development against poultry viral diseases.

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Book SynopsisAdvances in medical care and technology during the latter half of the 20th century have prolonged life expectancy in the United States. However, these same advances have blurred the boundary between life and death, challenging our expectations about how Americans could experience the end of life. Many individuals survive illnesses or traumatic injuries that would once have been fatal. For others, medical technology only serves to prolong survival in an unacceptable quality of life. Decisions concerning life and death issues affect a large and increasing number of individuals in the United States. This book discusses advance directives and advance care planning. It examines legal and policy issues, public engagement, and federal oversight, provider implementation and prevalence.

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Book SynopsisBriefly stated, comparative effectiveness research pertains to the direct, succinct and precise comparison of existing healthcare interventions to determine what works best for each individual patient, and which treatment course poses the greatest benefits, costs and harms. The core question of comparative effectiveness research goes beyond establishing what treatment works best, for whom, and under what circumstances: it is a hypothesis-driven endeavor designed to uncover and implement the consensus of the best evidence base for patient-centered, effectiveness-focused and evidence-based health care. Members at the Institute of Medicine and the Patient-Centered Outcomes Research concur that comparative effectiveness research involves the generation and synthesis of the best available evidence for a treatment intervention by means of a process driven by the PICOTS question/hypothesis, and are directed at comparing and contrasting the benefits, costs and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical conditions with the specified intent of improving the delivery of health care. The purpose of comparative effectiveness research is to assist healthcare providers, patients, allied clinicians, caregivers and other stakeholders to engage together and make informed decisions that will improve healthcare at both the individual and population levels, and in so doing utilize the identified best evidence base in specific clinical settings, a process that the Agency for Healthcare Research and Quality defines as "Translational Effectiveness". In brief, comparative effectiveness research is the tool and the process necessary for translational effectiveness. In this light, it is critical and timely to facilitate comparative effectiveness research as one of the essential and primary components of patient-centered, effectiveness-focused and evidence-based clinical decision-making in healthcare, as the premier process that results in improved patient outcomes, enhanced research planning, better products, and novel evidence-based policy development. This book is a compilation of the writings of several experts in the field and their collaborators. Each chapter examines specific facets of the process of comparative effectiveness research-based clinical decision-making in the principal domains of healthcare, which are subsumed in this work as dentistry, Western and alternative medicine, nursing, and pharmacology. Taken together, the chapters in this book present a brief, yet comprehensive overview and discussion of the current state of comparative effectiveness in healthcare. They establish the central role of systematic reviews in the process of clinical decision-making in evidence-based health care, and examine in depth the statistical significance and the clinical relevance of actualising and evaluating clinical decision-making. Additionally, policies in optimizing evidence-based, patient-centered and effectiveness-focused clinical outcomes, stakeholders engagement for raising health literacy in the U.S. and worldwide in this decade of the twenty-first century and beyond are discussed.

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Book SynopsisThis edited monograph contains five chapters that present advancements in the fields of medicine and biology. Chapter One provides a comprehensive review of the biological specimens used to monitor antipsychotic drugs as well as the analytical methods and sample preparation techniques used for their determination. Chapter Two focuses on estradiol and how it regulates the biology of innate and adaptive immune cell subpopulations, and how it may contribute to the resolution, exacerbation, or treatment for colorectal cancer. Chapter Three discusses the involvement of vitamin A in different areas such as embryonic development, development of the nervous system, and diseases. Chapter Four discusses environmentally friendly methods for the production of bismuth nitrate solutions and conditions for the hydrolytic purification of bismuth from the main metal impurities, specifies the compositions of the compounds used in medicine, and gives the production conditions for high purity bismuth compounds and the data on their toxicity. Finally, Chapter Five describes the use of gravitational mass spectroscopy to study the evolution of muscles.Table of ContentsPreface; Bioanalytical Methods for the Determination of Antipsychotics and Metabolites in Biological Samples; Role of 17B- Estradiol on Immune System Cells Function and Its Relationship with Colorectal Cancer; Pathophysiological Implications of Vitamin A in the Human Biological System; Processing of Bismuth to Produce Bismuth Compounds for Medicine; The Evolutionary Origin of Muscles; Index.

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Book SynopsisThis edited volume includes some of the latest research pertaining to the topics of health and disease. Chapter One examines the interplay between molecular redox signaling and the ubiquitin-proteasome system. Chapter Two discusses the origin and mechanism of antibody development, autoantibodies' association with disease, and the available therapeutic interventions. Chapter Three describes the microbial diversity of breast milk and the factors influencing this diversity. Chapter Four collects the evidence on adolescent bone growth, nutrition, physical activity, and hormonal changes related to occurrence of osteoporosis later in life. Chapter Five reviews evidence regarding the effects of allopurinol and febuxostat in kidney disease. Lastly, Chapter Six examines the phenomenon of elevated serum uric acid in patients with chronic kidney disease.Table of ContentsPreface; The Interplay between Molecular Redox Signaling and the Ubiquitin-Proteasome System: Relevant Aspects Related to Pathophysiological Processes in Human Diseases; Autoantibody, an Adaptive Immune Response: History, Structure and Evolution; Probiotic Microflora of Breast Milk and the Influence of Variable Factors; Adolescent Nutrition: A Link to Prevention of Post Menopausal Osteoporosis; Successful Control of Hyperuricemia in Chronic Renal Failure; Serum Uric Acid Fluctuations during Hemodialysis: Clinical Implications; Index.

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Book SynopsisIn this edited volume, updates in the field of health and disease are presented. Chapter One studies the incidence of hearing loss in patients with congenital cytomegalovirus infections. Chapter Two reviews the current literature concerning the multifactorial theories and etiologies of glaucomatous optic disc change and visual field loss in patients with normal-tension glaucoma. Chapter Three discusses the effectiveness of endovascular treatment for peripheral arterial disease, which is common in dialysis patients. Chapter Four describes a new technique for severely calcified infrapopliteal artery lesions called "percutaneous intraluminal needle cracking." Chapter Five aims to identify the occurrence of chronic kidney disease in the family members of chronic hemodialysis patients. Chapter Six describes methods for the outpatient management of oncologic patients with solid tumors and febrile neutropenia. Chapter Seven ascertains the suitability of peritoneal dialysis as a first choice for treatment of acute kidney injury patients. Chapter Eight reports on the application of a cathodically pretreated boron-doped diamond electrode for the determination of phenylbutazone using the differential pulse voltammetry, as a simple alternative method for quality control of this drug. Chapter Nine investigates the liaison between contaminated foods and the occurrence of illness in consumers to provide a clear picture of reports during the years 2010-2020. Lastly, Chapter Ten reviews the benefits and limitations of sodium-glucose cotransporter 2 inhibitors and the evidence behind the recommendations to support their use in different patient populations.Table of ContentsPreface; Hearing Loss in Congenital Cytomegalovirus (CMV) Infection in Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; The Multifactorial Pathogenesis of Normal Tension Glaucoma: A Brief Review; Effectiveness of Endovascular Treatment for Peripheral Arterial Disease in Dialysis Patients in Japan; Novel Technique of Percutaneous Intraluminal Cracking Using Puncture Needles for Severely Calcified Infrapopliteal Artery Lesions; Chronic Kidney Disease Occurrence and Treatments in the Family Members of Hemodialysis Patients; Outpatient Management of Oncologic Patients with Solid Tumors and Febrile Neutropenia; Renal Replacement Therapy in Acute Kidney Injury: The Role and Benefits of Peritoneal Dialysis; An Improved Voltammetric Method for Quality Control of Veterinary Pharmaceuticals Containing Phenylbutazone; Investigation on Norovirus Occurrence in Foodstuffs during the Years 2010-2020; Sodium Glucose Cotransporter 2 Inhibitors: Not Just for Diabetes Anymore?; Index.

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Book SynopsisThis edited monograph includes eight chapters, each discussing recent advancements in the fields of medicine and biology. Chapter One provides information on the mechanisms of polyurethane degradation. Chapter Two reviews the inhibitory effect of chlorogenic acid on metabolic syndrome-related vascular endothelial cell damage, type 2 diabetes, hypertension, and dyslipidemia. Chapter Three investigates the development of fatigue of rat skeletal muscle under the action of water-soluble pristine C60 fullerenes as powerful antioxidants. Chapter Four discusses advances in the generation of immune cells from pluripotent stem cells and the potential of chimeric antigen receptor cells in cancer treatment. Chapter Five describes the targeted delivery of immunosuppressants. Chapter Six focuses on the in vitro degradation of biopolymers using enzymes and microorganisms. Chapter Seven reviews the risk factors for hearing loss in infants admitted to the neonatal intensive care unit and the management of such patients detected with hearing loss. Finally, Chapter Eight describes recently developed methods and tools used in physiological studies of human sensory neurons induced from human pluripotent stem cells.Table of ContentsPreface; Mechanism of Microbial Mediated Degradation of Polyurethanes; Effect of Chlogenic Acid: Inhibition of Obesity-Induced Vascular Endothelial Dysfunction of Metabolic Syndrome Development; Skeletal Muscle Fatigue Development under the Action of Water-Soluble Pristine C60 Fullerenes; Targeted Drug Delivery of Immunosuppressants; An Overview on the Microbial Degradation of Biopolymers and Recent Developments; Newborn Hearing Screening at the Neonatal Intensive Care Unit; Approaches to Generate Human Peripheral Sensory Neurons for Understanding the Physiology of Human Peripheral Sensing; Index.

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Book SynopsisThis edited monograph includes seven chapters, each discussing recent advancements in the fields of medicine and biology. Chapter One discusses the biomedical engineering must frequently develop a great variety of sensors by including information from performance of bio-samples (cell cultures or tissues), technical specifications of transducers, and constrains derived from electronic circuits. In this work it is described a methodology for real-time cell culture monitoring system design; analysing, modelling, and integrating into the design flow the electrodes, cell culture and test circuit's influences. Chapter Two contributes to a deeper understanding of the main pathways playing a role in the complex mechanisms triggered in Fe-treated organisms. Chapter Three describes one of the most important medical evolutions of the last decade is the development of personalised medicine. The success of personalised medicine depends on having accurate diagnostic tests that identify patients who can benefit from targeted treatment strategies. Over the last years, a large range of different omics have led to the development of valuable biomarkers, based on genomics, proteomics, transcriptomics, metabolomics etc. Only few attention has been paid to the study of glycomics, an attractive though not well known technology that can lead to the development of biomarkers in a variety of diseases. Chapter Four provides information that amoeboid protists are a taxonomically eclectic group encompassing 'amoebae' and 'amoeboflagellates'. They are single-celled organisms that move by a crawling-like motion, while extending pseudopodia (slender or finger-shaped protrusions) from the periphery of the cell. Their shape is highly variable; and the number and organization of the pseudopodia, in addition to cell shape, are important features used to categorize and taxonomically identify the amoebae. Chapter Five subject dealt with in this chapter may be useful for improving strategies to treat certain diseases as well as for the design of materials for tissue engineering, among other applications. Chapter Six indicates that abnormalities in physical properties of the cell membranes may be strongly linked to hypertension and other circulatory disorders. Finally, Chapter Seven review that Diphtheria, known to be an acute toxin mediated, contagious febrile illness is caused by the bacterium Corynebacterium diphtheriae.Table of ContentsPreface; A Design Procedure for Sensing Cell Culture Assays Based on ECIS Technique; Iron Homeostasis and Oxidative Balance in the Context of Endotoxemia; The Use of Glycomics as Biomarkers in Liver Disease and Liver Transplantation; Amoeboid Protists: Biodiversity, Ecology and Role in Human Disease; Cell Motility Characteristics and Their Influence on the Global Colony Spreading Dynamics; Associations between Urinary Albumin Excretion Levels and Membrane Fluidity of Red Blood Cells in Hypertensive and Normotensive Subjects: An Electron Spin Resonance Study; Diphtheria: A Comprehensive Approach to Understanding the Disease, Diagnosis and Its Management; Index.

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Book SynopsisThis compilation presents some of the latest research in health and disease. Chapter One provides insight into the ophthalmic manifestations of dyslipidemia and how they may be managed concomitantly, with particular reference to the statins and their efficacy. Chapter Two proposes the application of personalized medicine for the treatment of hereditary hemorrhagic telangiectasia. Chapter Three summarizes the main studies in the field of psychological interventions for bariatric surgery patients exploring the advances on new online therapeutic and management strategies, and personalised medicine including stepped care approaches. Chapter Four examines the relationship between interpersonal stressors, coping with interpersonal stress, and sleep disorders focused on gender. Finally, Chapter Five describes the impact of exercises using a foam roller to reduce back pain in scoliosis patients.Table of ContentsPreface; Ophthalmic Manifestations Associated with Dyslipidaemia and Their Management; Hereditary Haemorrhagic Telangiectasia towards a Personalized Medicine to Promote Physical and Mental Health; Alternative Healthcare Delivery Strategies to Prevent Weight Regain after Bariatric Surgery; Gender Differences and Similarities in the Relationship between and Coping with Interpersonal Stressors, and Sleep Disorders in Employees; Use of Foam Roller for Myofascial Release Together with Postural Control for Reducing Back Pain in Scoliosis Patients: An Exercise Protocol; Index.

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Book SynopsisThis volume, comprised of six chapters, presents some of the latest advancements in medicine and biology research. Chapter One investigates six linear traits of three species of beetles in the Southern Siberian and North Caucasus mountains. Chapter Two analyses the efficiency of surgical treatment of tuberculosis, which remained common in Russia despite the development of efficient and less invasive drug therapies. Chapter Three summarises the literature on temporomandibular joint arthrocentesis. Chapter Four discusses the neuroprotective effects of some of the most used nutraceutical compounds and their possible future neuro-therapeutic role. Chapter Five examines the neurological differences in emotional processing between males and females. Lastly, Chapter Six assesses sexual dimorphism using the NumPy library for the Python programming language by creating digital analogue arrays of the histochemical activity of the acid phosphatase, alkaline phosphatase, adenosine triphosphatase and peroxidase using the example of sebaceous and eccrine glands of the skin of male and female Norway rats.Table of ContentsPreface; Sexual Size Dimorphism in Ground Beetles and Its Variation in Altitude Gradient; Invasive Procedures with Unproven Efficiency (Part 2): Surgical Treatment of Tuberculosis; Arthrocentesis Treatment in Temporomandibular Joint Disc Displacement without Reduction: A Review of the Literature; Nutraceuticals: Pharmacological Beneficial Effect and Their Role in Neuroprotection; Sex Differences in Neural Processing of Emotions: An Overview; Bioinformatics Analysis of the Sexual Dimorphism of the Skin Glands Histoenzymatic Activity in Norway Rats (Rattus norvegicus); Index.

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Book SynopsisThis volume includes some of the latest research in the fields of medicine and biology. Chapter One discusses various technologies for the repair of skin tissue. Chapter Two reviews the pathophysiology, symptoms and treatment of diseases. Chapter Three illustrates how an understanding of colloidal behaviour of proteins can enhance product development of biologics such as antibodies and antibody drug conjugates. Chapter Four deals with the characteristics and clinical significance of TP53 abberations in chronic lymphocytic leukaemia. Chapter Five examines the effect of dietary histidine supplementation on growth, muscle cellularity and critical swimming of meagre Argyrosomus regius larvae, whereas Chapter Six deals with the combined effect of water temperature and dietary protein on this organism. Chapter Seven sheds light on the possible major and minor factors leading to exacerbation and induction of the different forms of urticaria.

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Book SynopsisThis volume includes five chapters dealing with some of the latest advances in medicine and biology. Chapter One pontificates on the impact of the sequencing of the human genome on the search for life in the universe. Chapter Two summarizes current understanding of how to assess endothelial dysfunction, main risk factors, mechanisms underlying its development, prognostic implications, and biomarkers. Chapter Three assesses the effects of the hormone irisin on glucose metabolism. Chapter Four highlights the common disorders that need to be considered as a differential diagnosis for neuromyelitis optica spectrum disorder and features that help in their differentiation. Finally, Chapter Five deals with tapered modular femoral components in revision total hip arthroplasty.Table of ContentsPreface; Space Medicine: The Impact of Sequencing Human Genome on the Search for Life in the Universe; Endothelial Dysfunction in Children and Young Adults: Clinical Implications and New Perspectives; Effects of the Hormone Irisin on the Glucose Metabolism; Differential Diagnosis of Neuromyelitis Optica Spectrum Disorder; Tapered Modular Femoral Components in Revision Total Hip Arthroplasty; Index.

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Book SynopsisThis volume includes eight chapters detailing recent advances in the fields of medicine and biology. Chapter One reviews in vitro animal and clinical findings on the antioxidant properties of Crocus sativus L. and its constituents. Chapter Two discusses advances in the possible role of non-selective channels in muscular denervation and dystrophies. Chapter Three presents a standardisation of a testicular irradiation protocol in rats and an assessment of the histopathological and morphometric-stereological changes on the testes and epididymis, and vitality, concentration, and morphology of sperm according to a crescent curve of ionising radiation dose, which is relevant for cancer treatments. Chapter Four describes the classical aspects of bovine mastitis and its underlying gene networks. Chapter Five reviews the aetiologies, pathophysiology, and diagnostic work-up of acute aortic regurgitation and highlights key principles in its management. Chapter Six assesses the advantages and disadvantages of different surgical options for Charcot-Marie-Tooth disease. Chapter Seven provides an overview of molecular mechanisms responsible for the development of urticaria as well as molecular therapeutic agents under development for the treatment of urticaria. Finally, Chapter Eight describes recent guidelines for diagnosis and management of various types of urticaria.

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Book SynopsisThis volume includes eight chapters which describe recent advances in medicine and biology. Chapter One summarises new therapeutics for the treatment of optic neuritis, a condition involving primary inflammation, demyelination, and axonal injury of the optic nerve. Chapter Two uses animal models of viral myocarditis to study the natural history, genetics, pathogenesis, and clinical manifestation of viral myocarditis in humans. Chapter Three evaluates the functions of fibroblast growth factors in physiological mechanisms, their role in maintaining homeostatic balance, their role in signal transduction regulation, metabolism and interactions between organisms, and their relationship with diseases. Chapter Four investigates the potential of antibiotics to fight against the inherently nonspecific adaptation mechanisms of bacteria. Chapter Five deals with new methodologies for drug development to counter the evolution of mechanisms to resist antibiotics such as efflux pumps in bacteria that cause infectious disease. Chapter Six concerns the development of new therapeutic strategies regarding the involvement of brain neuropeptides in alcohol use disorder. Chapter Seven examines growth promotion and changes in functional constituents through arbuscular mycorrhizal fungi symbiosis in Asian ginseng. Finally, Chapter Eight explicates procedures for postoperative care in thoracic surgery.Table of ContentsPreface; New Perspectives in the Therapeutics of Optic Neuritis; Viral Myocarditis from Animal Models to Human Diseases; Fibroblasts and their Biophysiological Effects; Multidrug Efflux Pump, Adequacy and Multi-Resistance. Is it Possible to Fight against the Inherently Nonspecific Adaptation Mechanism Only with Antibiotics?; Profiles of Genetic Expression Associated with Resistance to Antibiotics; New Methodology for New Drugs Development; Involvement of the Substance P/Neurokinin-1 Receptor System in Alcohol Use Disorders; Growth Promotion and Changes in Functional Constituents through AMF Symbiosis in Asian Ginseng; Postoperative Care in Thoracic Surgery: How to Do It; Index.

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Book SynopsisThis volume includes eight chapters describing recent advancements in medicine and biology. Chapter One describes molecular communication among legume and rhizobia in the early stages of symbiosis. Chapter Two gives a comprehensive review of the physiochemical, pharmacological and pharmacokinetic properties of diclofenac, a nonsteroidal anti-inflammatory drug. Chapter Three dissects the novel aspects of the glucocorticoid receptor mechanism of action covering the latest findings that reveal the roles of heat-shock protein 90-binding immunophilins managing the glucocorticoid action and how these proteins influence biological response. Chapter Four explains a technique for in vitro fertilization-embryo transfer in women with diminished oocyte reserve that pays strict attention to not down-regulating key follicle stimulating hormone receptors. Chapter Five describes the use of four-dimensional computed tomography for the detection of enlarged parathyroids in the management of primary hyperparathyroidism. Chapter Six reveals the changes in the blood concentration of cell-free DNA and a number of biochemical and hemocytological parameters in the early stages of radiation cystitis development after local irradiation of the female rat pelvic region. Chapter Seven includes an evaluation of the safety and efficacy of paediatric appendectomy as compared to antibiotic-only treatment. Finally, Chapter Eight discusses a novel four-dimensional computed tomography technique that consists of sixteen different contrast phases instead of three or four phases, enabling detection of structures with a very short enhancement pattern.

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Book SynopsisThis ten-chapter volume presents some recent advancements in health and disease. Chapter One explains the increased mortality rate owing to atherothrombosis and cardiovascular diseases. Chapter Two reviews the evidence for all current management strategies for recurrent hypoglycaemia in diabetes. Chapter Three provides information on the relationship between obesity and circulating levels of C-reactive protein. Chapter Four describes high-sensitivity C-reactive protein as a biomarker of diabetes and hypertension. Chapter Five studies the combination of two self-associating biopolymers such as high-molar-mass hyaluronan and chitosan for treatment of skin wounds. Chapter Six outlines an integrated approach to address the issues of high levels of stress and burnout in the workplace. Chapter Seven examines pericoronary adipose tissue as a possible storage and supply site for lipoproteins and apolipoproteins in the human coronary artery. Chapter Eight deals with corneal collagen cross-linking protocols for the management of keratoconus. Chapter Nine discusses free radicals, their formation and catabolism, and their beneficial and adverse effects on cellular activities. Finally, Chapter Ten details various diagnostic tests for vasculitis.Table of ContentsPreface; Tissue Factor and Human Pathologies: A Comprehensive Insight; Management Strategies for Recurrent Hypoglycaemia in Diabetes; The Link between CRP and Obesity: Evidence from Human and Animal Studies; High-Sensitivity C-Reactive Protein: A Biomarker Linking Type 2 Diabetes and Hypertension to Cardiovascular Disease; Self-Associating Chitosan-Hyaluronan Carrier for a Drug Treating Injured Skin; Understanding and Managing Stress and Burnout: Roadmap for Success; Pericoronary Adipose Tissue as Possible Storage and Supply Site for Lipoproteins and Apolipoproteins in Human Coronary Artery; Corneal Collagen Cross-Linking Protocols for the Management of Keratoconus; Free Radicals and the Role of Antioxidants in Health and Disease; Diagnostic Tests in Vasculitis; Index.

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Book SynopsisThis volume includes six chapters detailing recent advances in medicine and biology. Chapter One provides an overview of protein changes that occur in patients on peritoneal dialysis treatment. Chapter Two evaluates the active production of superoxide anions by granulocyte colony-stimulating factor using Cypridina luciferin analogue-dependent chemiluminescence. Chapter Three focuses on a combination of polymers for mimicking biological, chemical, and physicomechanical properties of the extracellular matrix. Chapter Four examines visual interventions for children with developmental dyslexia. Chapter Five suggests that a comprehensive repertoire of signalling and metabolic remodelling mechanisms may explain the evolutionary resilience of bacteria over geological eons. Lastly, Chapter Six analyses measurements of the proton spin-lattice relaxation rate in malignant and non-malignant ascites.

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Book SynopsisThis volume presents some of the latest research updates related to health and disease. Chapter One investigates how traditional Chinese medicine can be leveraged in service of assisted reproductive technology. Chapter Two includes details about several drugs used in the treatment of rheumatoid arthritis. Chapter Three reviews the changing perspective of infection prevention and control measures in maternal and child healthcare settings. Chapter Four examines the role that infection control nurses play in the infection prevention and control teams of healthcare centers. Chapter Five explores some psycholinguistic aspects of illness narratives in patients with pulmonary hypertension as a therapeutic means to lessen patients' disease-related burden and promoting the sense-making of their illness experience. Lastly, Chapter Six highlights the prognostic value of various microRNAs with reference to chronic kidney disease.Table of ContentsPreface; The Role of Traditional Chinese Medicine (TCM) in Assisted Reproductive Technology (ART); Investigation of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate; Infection Control and Prevention: An Imperative Core Component in Maternal and Child Health; Infection Control Nurses: The Flag-Bearer of the Infection Prevention and Control (IPC) Team; The Correlates of the Reflective Processes in Illness Narratives of Female Patients Affected by Pulmonary Hypertension; Prognostic Value of MicroRNA Profiles in Chronic Kidney Disease: A Review; Index.

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Book SynopsisThis volume includes eight chapters that provide updates on recent advances in health and disease research. Chapter One reviews the clinical uses of mitomycin C in the eye and its complications. Chapter Two reviews the current knowledge and understanding on the regulatory mechanisms and pathophysiology of urinary stone disease. Chapter Three discusses how the Association of Southeast Asian Nations deals with the COVID-19 pandemic and how it adapts its disaster management mechanisms with its existing bureaucracy. Chapter Four describes the applications of computed tomography scans in the assessment of craniofacial morphology. Chapter Five discusses the work done using scanning electron microscopy-energy dispersive X-ray spectroscopy to describe the structural and compositional investigations in kidney stones and its evolution over the decades. Chapter Six deals with the complex host-microbe interactions associated with the pathogenesis of post-COVID mucormycosis and its management in the primary and revision scenario. Chapter Seven highlights the potential role of Vitamin D and Vitamin D receptor gene polymorphism in the prognosis of kidney stone formation through extensive secondary data. Finally, Chapter Eight examines the utility of village folklore medicines for management of stress and other applications.

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Book SynopsisThis volume includes eight chapters that detail recent advancements in the field of health and disease. Chapter One investigates the interaction of molybdenum complexes and polyoxometalates with DNA models. Chapter Two discusses the role of superoxide dismutase in sperm capacitation. Chapter Three details various imaging techniques for diagnosis of hepatic steatosis. Chapter Four compares and contrasts dietary supplementation advice for pregnancy from different countries around the world. Chapter Five reviews common electrolyte abnormalities in critically ill patients and provides advice regarding their management. Chapter Six explores the heterogeneity across the spectrum of HDL cholesterol subpopulations and the main components of HDL that participate in the biological activities of HDL. Chapter Seven discusses strategies for the optimization of umbilical cord blood banking. Finally, Chapter Eight concerns the involvement of the breast in granulomatosis with polyangiitis.Table of ContentsPreface; The Interaction of Molybdenum Complexes and Polyoxometalates with DNA Models; Superoxide Dismutase Participation in Sperm Capacitation; Diagnosis of Hepatic Steatosis by Imaging; International Differences Regarding Pregnancy Supplementation Advice; Electrolyte Imbalance and Fluid Management in Critical Patients; The Fascinating Complexity of HDL: From Biogenesis to Function; Optimisation of Umbilical Cord Blood Banking; Breast Involvement in Granulomatosis with Polyangiitis (GPA); Index.

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Book SynopsisThis book presents some recent updates in health and disease. Chapter One provides an overview of facioscapulohumeral muscular dystrophy. Chapter Two summarizes the recent research findings related to the pathogenesis of E. histolytica. Chapter Three summarizes the literature concerning the role of fluoride in osteogenesis. Chapter Four investigates the utility of ultrasound elastography in detection of liver disease. Chapter Five evaluates the efficiency of health services of some countries during the COVID-19 pandemic. Chapter Six describes treatment options for petroclival meningiomas. Chapter Seven explains the uses, mechanisms of actions and clinical outcomes of ibuprofen. Chapter Eight defines and describes limb-girdle muscular dystrophies, including its clinical manifestations, diagnostic strategies, and treatment options. Finally, Chapter Nine discusses the diagnosis of methamphetamine-related poisoning and death, including pathophysiological and toxicological findings, in forensic practices.Table of ContentsPreface; An Overview of Facioscapulohumeral Muscular Dystrophy; Understanding Entamoeba histolytica Pathogenesis: In Light of Recent Advancements; The Role of Fluoride in Osteogenesis; Utility of Ultrasound Elastography in Detection of Liver Disease in Areca Nut Habitual; Efficiency Evaluation of Health Services of Selected Countries during the COVID-19 Pandemic; Petroclival Meningiomas; Ibuprofen: Uses, Mechanisms of Action and Clinical Outcomes; Limb-Girdle Muscular Dystrophy: A Review; Forensic Diagnosis of Methamphetamine Poisoning and Methamphetamine-Related Deaths; Index.

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Book SynopsisThe International Conference and Exhibition on The Indonesian Medical Education Research Institute (ICE on IMERI) is a yearly conference presented by The Indonesian Medical Education Research Institute (IMERI). This year, the 6th ICE on IMERI with the selected theme "Biomedical Research and Primary Care Transformation: The Potential Issue in Post Pandemic Era" provides a panel of experts on relevant topics. This book contains selected academic papers submitted to the 6th ICE on IMERI editorial team by participants. Primary care needs adjustment during the era of the Covid-19 pandemic. This book presents various case studies, reviews, and original articles that provide a new perspective on health care settings during the pandemic. Articles about novel therapy, diagnosis, and prognosis regarding Covid-19 and other health-related topics can be found in this book.

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Book SynopsisThis book includes nine chapters that describe recent advances in health and disease. Chapter One discusses controversies regarding the use of intraoperative cell salvage during surgery involving bacterial contamination or malignancy. Chapter Two presents an overview of clinical applications of all-trans retinoic acid. Chapter Three explores the role of angiotensin-converting enzyme 2 receptors in COVID-19 infection. Chapter Four describes potentially beneficial sports supplements for endurance athletes. Chapter Five studies the influence of low-impact aerobic physical activity on Berger's disease. Chapter Six evaluates the effects and toxicity features of paclitaxel nanoformulations. Chapter Seven examines a potential link between methamphetamine abuse and glycogen synthase kinase-3. Chapter Eight investigates the health-promoting potential of tryptophan-derived betalin. Finally, Chapter Nine deals with the role of glucagon in exploring the corticotrop pituitary reserve.Table of ContentsPreface; Can We Overcome the Obstacles to Modern Intraoperative Cell Salvage Transfusion? A Detailed Review of Current Evidence; Advanced Formulation of All-Trans Retinoic Acid for Combination Therapy in Cancer; Circulating Angiotensin-Converting Enzyme 2 (ACE2) and Angiotensin-(1-7) [Ang-(1-7)] in COVID-19 Patients; Sports Supplements in Endurance Sports: Practical Applications; Effect of Aerobic Physical Activity in Swimming and Cycle Ergometer on Proteinuria in IgA-Nephropathy: A Longitudinal Single Case study; Nanoformulations of Paclitaxel: Therapeutic or Toxic?; Glycogen Synthase Kinase-3b and Methamphetamine Abuse Liability; Health-Promoting Potential of a Natural Plant Pigment Based on Tryptophan; The Role of Glucagon in Exploring the Corticotrop Pituitary Reserve: Review of the Latest Evidence; Index.

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Book SynopsisClinical Cases in Dermatologic Surgery is a collection of over 30 cases on cutaneous defect repairs and skin cancer management. Written by experts in the field of Mohs surgery and advanced closure techniques, this book is a practical resource for all doctors practicing skin cancer surgery. Organised by anatomical region, each case presents a skin defect or tumour, and readers are asked several questions to test their knowledge and understanding of management, including initial reconstruction, precautions, after-care, management of complications and revision.Features:• Problem-based learning scenarios, encouraging critical thinking to promote active learning, allowing users to test their knowledge and demonstrate their comprehension of which technique to use, potential risks and how to mitigate these. • Cases aligned to Dermatologic Surgery: A manual of defect repair options 2e and accompanying videos, with the same order of site-based sections for easy cross-reference.• Questions and answers provided for each case with alternative approaches included.

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