Life sciences: general issues Books
CRC Press Artificial Intelligence Models for the Dark
Book SynopsisThe dark universe contains matter and energy unidentifiable with current physical models, accounting for 95% of all the matter and energetic equivalent in the universe. The enormous surplus brings up daunting enigmas, such as the cosmological constant problem and the apparent distortions in the dynamics of deep space, and so coming to grips with the invisible universe has become a scientific imperative.This book addresses this need, reckoning that no cogent physical model of the dark universe can be implemented without first addressing the metaphysical hurdles along the way. The foremost problem is identifying the topology of the universe which, as argued in the book, is highly relevant to unveil the secrets of the dark universe.Artificial Intelligence (AI) is a valuable tool in this effort since it can reconcile conflicting data from deep space with the extant laws of physics by building models to decipher the dark universe. This book explores the applications of AI a
£71.24
Cambridge University Press Writing Undergraduate Lab Reports
Book SynopsisWriting clear, impactful reports is a crucial skill for science students, but few books focus on this area for the undergraduate. Particularly useful for biology students, this text adopts a hands-on approach, using example reports and published papers as models to put guidance into practice. An introductory chapter familiarizes undergraduates with the principles of writing science. Two model reports are then developed, walking students through experimental and observational teaching-lab reports. The structure and content of the Introduction, Methods and Materials, Results, and Discussion are explained, together with tips for the title, abstract, and references. Students are then guided on how to polish their first draft. The last section of the book analyzes two published papers, helping the reader transition to reporting original research. Clearly and concisely written, this text offers a much-needed lifeline for science students facing science report-writing for the first time, and Trade Review'This guide for undergraduates - lightweight, and peppered with illustrations and diagrams - will demystify the process of creating an effective lab report. … This text's straightforward approach and rich but concise details make this item an invaluable resource for science majors and elective takers alike.' J. Clemons, ChoiceTable of ContentsAcknowledgements; To the student; Part I. Introduction: 1. Introduction to science and scientific writing; Part II. Writing the First Draft: Format: 2. Starting to write; 3. Introduction; 4. Materials and methods; 5. Results; 6. Discussion; 7. Title and abstract; Part III. Crafting the Final Version: Scientific Style: 8. Revising your paper; 9. References; Part IV. The Anatomy of Scientific Papers: 10. Transitioning to writing about original research; References; Further reading; Index.
£19.99
CRC Press Plasma Discharge in Liquid Water Treatment and
Book SynopsisPlasma methods that effectively combine ultraviolet radiation, active chemicals, and high electric fields offer an alternative to conventional water treatment methods. However, knowledge of the electric breakdown of liquids has not kept pace with this increasing interest, mostly due to the complexity of phenomena related to the plasma breakdown process. Plasma Discharge in Liquid: Water Treatment and Applications provides engineers and scientists with a fundamental understanding of the physical and chemical phenomena associated with plasma discharges in liquids, particularly in water. It also examines state-of-the-art plasma-assisted water treatment technologies.The Physics & Applications of Underwater Plasma DischargesThe first part of the book describes the physical mechanism of pulsed electric breakdown in water and other liquids. It looks at how plasma is generated in liquids and discusses the electronic and bubble mechanism theories for how the electric discharge in liquid is initiated. The second part of the book focuses on various water treatment applications, including: Decontamination of volatile organic compounds and remediation of contaminated water Microorganism sterilization and other biological applications Cooling water treatment Drawing extensively on recent research, this one-stop reference combines the physics and applications of electric breakdown in liquids in a single volume. It offers a valuable resource for scientists, engineers, and students interested in the topic of plasmas in liquids.Trade Review"The approach and selection of topics are relevant to the technology for effective water treatment. The book can be useful to the researchers and students in this field, and can provide practical solutions for water treatment technology. In addition this book may aid knowledge in usage of plasma technology in other liquid domain."—Rupak K. Banerjee, PhD, PE, Fellow ASME, University of Cincinnati and Kallol Bera, PhD, Applied Materials, Inc., California, USATable of ContentsIntroduction. Generation of Plasma in Liquid. Bubble and Electronic Initiation Mechanism. Decontamination of Volatile Organic Compounds. Biological Applications. Cooling Water Treatment Using Plasma. References. Index.
£96.99
Palgrave Macmillan Biology Computing and the History of Molecular Sequencing
Book SynopsisSequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.Trade Review"Overall, this book provides a detailed time line of the events from the earliest methodologies to the metagenomic sequencing standard of today, and is a useful resource for anyone interested in the historical angle of DNA sequencing. Highly recommended." - M.C. Pavao, Worcester State College, Choice "...an invaluable, possibly even essential, addition to the bookshelf of anyone wishing to understand modern biology in all its facets...The author has done a masterful job of integrating information about the way in which different aspects of computer science...have contributed to the development of sequencing." - Neeraja Sankaran, British Journal for the History of Science, 46: 544 "...a revised dissertation, grounded in a remarkable variety of primary sources including corporate records and oral history interviews." - Ruth Schwatz Cowan, American Historical Review, June 2013: 827 "...a timely and informative history of molecular sequencing ... Overall, Garcia-Sancho's book provides a highly readable and insightful analysis of the history of molecular sequencing, one that should be appreciated for its broad synthesis of existing scholarship and its extensive use of historical documents.." - Doogab Yi, History and Philosophy of the Life Sciences "Supported by an impressive archival and oral research, and by a thorough revision of the secondary literature of the field, García-Sancho´s book is a celebration of what the history of recent and contemporary science can achieve, and for years to come it will remain as an obliged reference not only for historians of science, but for sociologists and all those interested in the detailed development of the industrialized-information society." - Edna Suarez-Diaz, DynamisTable of ContentsIntroduction: An Historical Approach to Sequencing PART I: EMERGENCE: FREDERICK SANGER'S PIONEERING TECHNIQUES (1943-1977) The Sequence of Insulin and the Configuration of a New Biochemical Form of Work (1943-1962) From Chemical Degradation to Biological Replication (1962-1977) PART II: MECHANISATION – 1: COMPUTING AND THE AUTOMATION OF SEQUENCE RECONSTRUCTION (1962-1987) Sequencing Software and the Shift in the Practice of Computation Sequence Databases and the Emergence of 'Information Engineers' PART III: MECHANISATION – 2: THE SEQUENCER AND THE AUTOMATION OF SEQUENCE CONSTRUCTION (1980-2000) A New Approach to Sequencing at Caltech The Commercialisation of the DNA Sequencer Conclusions: A Long History of Practices Appendix 1: Oral Histories Appendix 2: Archival Sources Notes Bibliography
£999.99
Springer-Verlag New York Inc. Essential IVF
Book SynopsisThere is no clearer testament to the importance and efficacy of in vitro fertilization in the treatmentof the infertilepatient than the fact that over one million babies have been born since its clinical introduction in 1978. The successof this worldwideendeavorhas evolvedto treat some of the formerly most intractable forms of infertility and requires individuals with different skills and insights whose activities are often compartmentalized into clinical, laboratory and research functions. The intent of Essential lVF is to present current issues in clinical IVF that encompass the varied activities of those engaged in this enterprise. By integrating clinical, basic research and laboratory-related aspects of human reproduction, readers with diverse interests should obtain a more complete understanding of the impact, importance and inter-relatedness of each in the progress of inferTable of ContentsOne The Synthetic and Secretory Behaviors (Nonsteroidal) of Ovarian Follicular Granulosa Cells: Parallels to Cells of the Endothelial Cell Lineage.- Two Oocyte-Granulosa Cell Interactions.- Three Peri-Follicular Vascularity: A Marker of Follicular Heterogeneity and Oocyte Competence and a Predictor of Implantation in Assisted Conception Cycles.- Four do Biochemical Predictors of IVF Outcome Exist?.- Five Genetics of Male Infertility: Evolution of the X and Y Chromosome and Transmission of Male Infertility to Future Generations.- Six Sperm Analysis and Preparation Update.- Seven Preparation of Sperm Fractions and Individual Sperm With Low Levels of Chromosomal Aneuploidies for IVF And ICSI.- Eight Maternal Age and Oocyte Competence.- Nine Genetic Diagnosis of Metaphase II Oocytes.- Ten Oocyte Competence and In Vitro Maturation.- Eleven What is the Role of Mitochondria in Embryo Competency?.- Twelve Fundamentals of the Design of Culture Media that Support Human Preimplantation Development.- Thirteen the Biological Basis of Oocyte and Embryo Competence: Morphodynamic Criteria for Embryo Selection in In-Vitro Fertilization.- Fourteen the Enigma of Fragmentation in Early Human Embryos: Possible Causes and Clinical Relevance.- Fifteen Blastocyst Transfer Update: Pros and Cons.- Sixteen Assisted Hatching in Clinical IVF.- Seventeen Prospects for Obtaining Viable Oocytes from Cryopreserved Ovarian Tissue.- Eighteen Cryopreservation in Human Assisted Reproduction.- Nineteen Reducing the Number of Embryos to Transfer After IVF/ICSI.- Twenty Can and Should Human Embryos be “Rescued” from Developmental Demise? Methods and Biological Basis.- Twenty-One Determination of Endometrial Status and the Implantation Window.
£999.99
Taylor & Francis Inc Advanced Particle Physics TwoVolume Set
a huge range and FREE tracked UK delivery on ALL orders.
£372.81
Springer-Verlag New York Inc. Brute Force
Book SynopsisSeveral years later, IBM responded with a system called Lucifer that came to simply be known as DES (data encryption standard).The strength of an encryption system is best measured by the attacks it is able to withstand, and because DES was the federal standard, many tried to test its limits.Trade ReviewFrom the reviews: An excellent story about the thousands of volunteers who battled to prove that the aging standard for date encryption was too weak and to wrestle strong cryptography from the control of the U.S. government...It is a worthy book for almost anyone who has a computer. -Louis Kruh, Cryptologia, Volume 30, 2006 Brute Force is about as entertaining a read as you will get on cryptography. It provides a detailed account of how DES was taken down and is an interesting read for any student of cryptography and the crypto wars of the 1990s. -Ben Rothke, UnixReview.com, September 2005 Matt Curtin was right at the heart of the Deschall cracking effort, and his book is excellent in describing the day-to-day progress towards the goal... -Richard Clayton, Times Higher Education Supplement (U.K.), October 2005 "This book is an exciting popular account of an important event nearly ten years ago in the social history of cryptography. … The book is written to tell the story of how the DESCHALL (Des challenge) project came together, to encourage interest in cryptography amongst the young and to make the subject more accessible to people. It would seem to be successful on all counts." (P. D. F. Ion, Mathematical Reviews, Issue 2006 j) "DESCHALL’s goal was to search through 72 quadrillion keys to demonstrate the feasibility of a brute force attack on DES … . Curtin starts with the genesis of DES … . he manages to keep interest alive with a taut but lively prose, a focus on the human element of the story … . the non-technical reader will appreciate the evocative similes … . Perhaps most intriguing in Curtin’s narrative are … the human and social aspect of divvying up the workload … ." (Daniel Bilar, MathDL, November, 2005)Table of ContentsContents Introduction 1. 90MHZ Pentium 2. Data Encryption Standard 3. Key Length 3.1 Symmetric Cryptography 3.2 Codes 3.3. Susceptibility to Brute Force Attacks 3.4 Substitution Ciphers 3.5 Asymetric Cryptography 4. RSA Crypto Challenge 5. Law Enforcement Concerns 6. Supercomputer 7. Show Me the Code 8. Project Follows Code 9. Organizing DESCHALL 10. Announcing DESCHALL 11. Getting Attention 12. Front Running 13. Haystack 14. Clients 14.1 Verser DES Key Search Method 14.2 More Speed for Intel 15. Architecture 15.1 Boot Disks 15.2 Client Management 15.3 Dialup Users 15.3.1. Dialup in Windows 15.3.2. Dialup in OS/2 16. Every Machine Counts 17. Competition 18. Summer Vacation 19. 100% CPU 20.Transition 21. Requests 22. Perseverance 23. Network 24. Download 25. SolNET 26. Get Off Your Duff 27. Short Circuit 28. Media 29. Volume 30. Too Much Is Never Enough 31. Proposal 32. In the Lead 33. Recruit 34. SolNET Drops Off 35. Threats 36. Crypto News 37. Rivalry 38. Overdrive 39. Disturbed 40. Back Door 41. Second Stage 42. Obstacle 43. DESGUI 44. Export 45. Keeping It Together 46. Getting Word Out 47. No DESCHALL Here 48. Schedule 49. SolNET Stumbles 50. A Few Hundred Clients 51. New Statistics 52. Bitslice 53. Crypto Battle 54. SolNET Recovers 55. Server Outrage 56. SGI 57. Netlag 58. Terminal Velocity 59. Photoshoot 60. Integrity 61. Workaround 62. Morale 63.Strong Cryptography Makes the World a Safer Place 64. Talking Head 65. Effect 66. Saying the Course 67. Five Years Later 68. Next Steps 68.1 Other Stuff A DESCHALL Press Release
£23.74
Macmillan Learning Principles of Life for the AP course
Book Synopsis
£75.04
Springer-Verlag New York Inc. Winning the Games Scientists Play
Book SynopsisThe interpersonal strategies that surround the act of doing good science--hereafter referred to as scientific game play ing-have received some published attention, and many of the game rules are almost axiomatic among successful prac titioners of science. There is a need, however, to review pe riodically what we know and what we think we know about the art, and to add new insights that become available. This book is a response to that need; it has been written for science practitioners and grandstanders of the 1980s, drawing on in Sights and perceptions gained from victories and defeats of the 1970s. It seems especially important that the strategies and rules of scientific game playing be reviewed critically as we move into the decade of the 1980s, since many of those rules have changed during the 1970s--in fact each recent decade has seen significant changes. The 1950s were expaTable of ContentsPrologue: The Importance of Interpersonal Strategies in Science.- One: A Primer For Scientific Strategists.- 1: The Scientist as a Writer: Publishing Scientific Papers.- Authorship of scientific papers.- The role of reviewers.- Scientific writing viewed from the editor’s desk.- Damming the paper flood.- Summary.- 2: The Scientist as a Performer: Presenting Scientific Papers.- How not to present a scientific paper.- Suggestions for better paper presentations.- How to enjoy presenting a scientific paper.- The so-called discussion following paper presentation.- The last word.- 3: The Scientist as a Face in the Crowd: Attending Scientific Meetings.- Strategies for meeting participation.- Funding meeting attendance.- Election to society offices.- International meetings.- Residues of scientific meetings.- Summary.- 4: The Scientist as a Concertmaster: Chairing Scientific Sessions.- Early planning.- The meeting.- Session follow-up.- Special assignments.- Summary.- 5: The Scientist as a Producer/Director: Organizing Scientific Meetings.- The annual meeting of a scientific society.- The workshop or small-group conference.- The international symposium.- Summary.- 6: The Scientist as a Negotiator: Participating in Committee Meetings.- The chairperson’s creed.- The committee members’ guide.- Some committee games.- Committee women.- The advisory committee.- Paper products of committee activities.- Computer conferences.- Summary.- Two: Critical Issues for Scientific Strategists.- 7: The Scientist in Transition: Moving Up, On, and Out.- The fast track.- Leaving the fast track.- Life stages of a scientist.- Eras in a professional career.- The “professional”.- Losing strategies.- Moving on.- Moving out.- Summary.- 8: The Scientist in Control: Getting and Using Power.- Kinds of power in science.- Power strategies.- Organizational variations in power.- Summary.- 9: The Scientist in Doubt: Defining Ethics in Science.- The perimeter of the circle.- Within the circle.- Maneuvers in ethical combat zones.- Summary.- Three: Special Interest Areas for Scientific Strategists.- 10: Evaluating the Roles of Women and Men in Science.- Sex in the laboratory.- Women in science.- Men in science.- 11: Coping with Bureaucracy and Bureaucrats.- Types of bureaucrats.- Common characteristics of bureaucrats.- The bureaucratic hierarchy.- Kinds of bureaucracies.- Summary.- 12: Dealing with External Forces: News Media, Lawyers, Politicians, and the Public.- News media.- Lawyers.- Politicians.- The public.- Summary.- 13: Relating to Industry.- Industrial game rules.- Consulting.- The scientist as an industry spokesman.- Summary.- Epilogue.- References.
£40.49
Taylor & Francis Inc Green Chemistry Laboratory Manual for General
Book SynopsisGreen chemistry involves designing novel ways to create and synthesize products and implement processes that will eliminate or greatly reduce negative environmental impacts. The Green Chemistry Laboratory Manual for General Chemistry provides educational laboratory materials that challenge students with the customary topics found in a general chemistry laboratory manual, while encouraging them to investigate the practice of green chemistry. Following a consistent format, each lab experiment begins with objectives and prelab questions highlighting important issues that must be understood prior to getting started. This is followed by detailed step-by-step procedures for performing the experiments. Students report specific results in sections designated for data, observations, and calculations. Once each experiment is completed, analysis questions test students' comprehension of the results. Additional questions encourage inquiry-based investigations and further research Trade Review"…a welcome change and direction for enriching the laboratory experience of students."— Colin F. Poole, Wayne State University, in Chromatographia."This book is designed as a laboratory manual ready to be used by students. It’s suitable for late secondary or elementary tertiary-level courses. … experiments highlight a feature also found in other chapters – the links made between chemistry and everyday life. This problem-based approach has to be lauded. Overall, this book provides an introduction to green chemistry and engages students in the process of challenging traditional methods by benchmarking them against the 12 principles of green chemistry."— Thomas Logothetis, for Education in Chemistry, August 2016."…a welcome change and direction for enriching the laboratory experience of students."— Colin F. Poole, Wayne State University, in Chromatographia."This book is designed as a laboratory manual ready to be used by students. It’s suitable for late secondary or elementary tertiary-level courses. … experiments highlight a feature also found in other chapters – the links made between chemistry and everyday life. This problem-based approach has to be lauded. Overall, this book provides an introduction to green chemistry and engages students in the process of challenging traditional methods by benchmarking them against the 12 principles of green chemistry."— Thomas Logothetis, for Education in Chemistry, August 2016.Table of ContentsDetermining the percent of water in epsom salt. Determination of the formula of a copper supplement. Determination of mass and mole relationships in a chemical reaction. Finding ethanol's molar mass using vapor density. Determining molar volume of a gas at standard temperature and pressure. Determining the enthalpy change for solvation reactions. Spectroscopic determination of food dye in popsicles. Separation of food dyes by paper chromatography. What is the best solution to lower a freezing point? Standardization of a sodium hydroxide solution. Determining the amount of acid in ketchup and hot sauce. Using an appropriate indicator for acid-base titrations. Preparation and properties of buffer solutions. Determination of the rate of reaction and its order. Equilibrium constant for ferric ion-salicylic acid complex determination. Determination of amount of ascorbic acid in a vitamin C tablet by redox titration. Qualitative analysis of metal cations and using ion-selective electrodes. How to determine the order of an electrochemical series. Voltaic cells and how batteries are made. Synthesis and chemical analysis of sodium iron (III) EDTA. Analysis of biodiesel synthesized from canola oil.
£80.74
Apple Academic Press Inc. Environmental Problems in Marine Biology
Book SynopsisMarine environment can be affected by several pollutants such as the presence of elements and their chemical species, pharmaceuticals, nanoparticles and other emerging contaminants. Environmental monitoring can be assessed by genomics, proteomics (i.e. redox proteomics), chemical speciation analysis and metallomics, metabolomics as well as other advanced strategies. The present book is a useful methodological tool for researchers and specialists in the field of analytical chemistry, environmental sciences, biochemistry, genomics and toxicology. The book includes for the first time the methodological aspects and applications related to chemical speciation and omics strategies applied to marine environment. Table of ContentsElement Speciation in Seawater: From Free Metal Determination to Proteomic Analysis. The Decisive Role of ICPMS and Related Hyphenated Techniques in Multielement and Speciation Analysis of Marine Biota. Mercury Speciation in Marine Biota and its Influence on Human Health: Metallomic and Metabolomic Approaches. Selenium Speciation in the Marine Environment. Arsenic Occurrence in Marine Biota: The Analytical Approach. Biological Effects of Organotins on the Marine Environment. Functional Genomics Approaches in Marine Pollution and Aquaculture. New Trends in Aquatic Pollution Monitoring: From Conventional Biomarkers to Environmental Proteomics. Protein Expression Profiles in Marine Organisms Exposed to Nanoparticles. Effects of Climate Change in Marine Organisms: A Proteomic Approach. Environmental Metabolomics and Toxicometabolomics in Marine Pollution Assessment. Fate and Toxicity of Inorganic Engineered Nanomaterials in the Marine Environment: Analytical Techniques and Methods. Pharmaceuticals in the Marine Environment: Analytical Techniques and Applications. Biological Effects of Pharmaceuticals on the Marine Environment.
£171.00
APress Python for the Life Sciences
Book Synopsis Treat yourself to a lively, intuitive, and easy-to-follow introduction to computer programming in Python. The book was written specifically for biologists with little or no prior experience of writing code - with the goal of giving them not only a foundation in Python programming, but also the confidence and inspiration to start using Python in their own research. Virtually all of the examples in the book are drawn from across a wide spectrum of life science research, from simple biochemical calculations and sequence analysis, to modeling the dynamic interactions of genes and proteins in cells, or the drift of genes in an evolving population. Best of all, Python for the Life Sciences shows you how to implement all of these projects in Python, one of the most popular programming languages for scientific computing. If you are a life scientist interested in learning Python to jump-start your research, this is the book for you. Table of ContentsPython for the Life Sciences 1. Getting Started with Python 2. Python at the Lab Bench 3. Making Sense of Sequences 4. A Statistical Interlude5. Open Doors to your Data 6. Finding Needles in Haystack 7. Object Lessons 8. Slicing and Dicing Genomic Data9. The Wells! The Wells! 10. Well on the Way 11. Molecules in 3D 12. Turning Genes on and off 13. Taming the Network Hairball 14. Genetic Feedback Loops 15. Growing a Virtual Garden 16. How the Leopard got its Spots 17. Foxes Guarding Hen Houses 18. A Virtual Flu Epidemic19. Retracing Life’s Footsteps
£44.99
Taylor & Francis Inc Introduction to Proteins
Book SynopsisIntroduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure, function, and motion of proteins for students, faculty, and researchers at all levels. The book covers proteins and enzymes across a wide range of contexts and applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. Each chapter includes a Summary, Exercises, and References.New features in the thoroughly-updated second edition include: A brand-new chapter on enzymatic catalysis, describing enzyme biochemistry, classification, kinetics, thermodynamics, mechanisms, and applications in medicine and other industries. These are accompanied by multiple animations of biochemical reactions and mechanisms, accessible via embedded QR codes (which can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs) A wider-scale description of Trade Review"This is the most interesting to read and complete text I have found for senior undergraduate or early graduate-level coverage of protein structure and function, and a great reference book to have on hand. This text is significantly updated and printed in a hardcover format with easy-to-read text (larger font and pages than usual, with margins for note-taking) and comes with annotatable ebook access for free. Overall, this is a significantly enriched 2nd edition of a book we have used successfully for several years now, which I enthusiastically recommend!" --Leslie Kuhn, Departments of Biochemistry & Molecular Biology and Computer Science & Engineering, Michigan State University, USA "I used this book when studying for a course on the Mechanisms of Enzyme Catalysis. The book made everything I was struggling with so clear! It is extremely well organized and very, very thorough which makes studying from it easy! 10/10 would recommend to anyone studying proteins and/or enzymes, or even someone who just wants to learn more. Anyone looking for a supplementary reading for your course should have this text book - even if you think you don't need it, trust me, you do." --Customer review on Amazon.com Praise for the First edition: "This book offers a unique combination of structure, thermodynamics and biology. I was impressed both by the breadth of the topics covered and by the depth in which they are treated. General principles are made intuitively clear based on well-chosen examples, many of them having relevance to disease. The book could fit well as a textbook in structural biology and molecular biophysics courses." --Barry Honig, Columbia University, New York, New York, USA "I’ve just lately used this textbook for a presentation on electrostatics. Although I have an organic background, I discovered that the explanations of electrostatic interactions are very clear and informative. The language isn’t too technical and may be easily understood by biology students. The textbook covers numerous examples and colorful illustrations, which made it easy to understand the principles discussed. The book is well organized in chapters for all the fundamental topics. I feel this book would be appropriate for any undergraduate and graduate scholar who’s keen on proteins. … It’s complete, easy to observe and (something I at least discover uncommon for textbooks) pleasing to read. The authors don’t shrink back from any subjects, but clarify things in a straightforward method supported by ample examples. Highly recommended." --Physics Book Reviews at dowdawgs.com, May 2013 "Introduction to Proteins is an excellent, state-of-the-art choice for students, faculty, or researchers needing a monograph on protein structure. …The book is clear, well organized, aptly illustrated in color, and a pleasure to read. The first two chapters are an impressive textbook unto themselves … The book is thoroughly documented with citations to the literature gathered at the end of each chapter. … Overall, this is an immensely informative, thoroughly researched, up-to-date text, with broad coverage and remarkable depth. Introduction to Proteins would provide an excellent basis for an upper level or graduate course on protein structure, and a valuable addition to the libraries of professionals interested in this centrally important field." --Eric Martz, Biochemistry and Molecular Biology Education, Vol. 40, 2012 "This is an important book. It captures in a very accessible way a growing body of literature on the structure, function and motion of proteins, and links this to more established paradigms such as a reader might find in a mainstream biochemistry text. The text is littered with excellent examples of the wider relevance of the material covered. The book is also exceptionally well written. I learned new things from each chapter. Overall, a superb publication that would be very useful to undergraduates, graduate students, postdoctoral researchers and instructors involved in structural biology or biophysics courses or in research on protein structure–function relationships. I would recommend it highly." --David Sheehan, ChemBioChem, 2011 "The book provides general guidelines for understanding protein structure and demonstrates how we can use the structure to phrase testable hypotheses about biological function. The repeated use of the same example makes it easier for the reader to grasp the general principles. The book gives a coherent picture of each topic and includes ample references, making it possible for the interested reader to dig deeply into various topics. The book also covers structural aspects of intrinsically unstructured proteins and how this property facilitates their biological function. It provides background in cell biology, basic chemistry and thermodynamics, making it useful for newcomers to the protein structure field who want to catch up quickly. It is also easy for experts to dive into the more specialized aspects quickly. The book provides references to user-friendly web tools in the field. The publisher’s website provides exercises on both theory and practice. Sample solutions and PowerPoint presentations are available for qualified teachers. These make the book attractive as the main textbook in an undergraduate course on protein structure, for parts of freshman biochemistry, and as a supplement for many undergraduate and graduate courses." --Burkhard Rost, Technische Universität München, Germany Table of ContentsIntroduction. Protein Structure. Methods of Structure Determination and Prediction. Energetics and Protein Stability. Protein Dynamics. Intrinsically Unstructured Proteins. Membrane-Bound Proteins. Protein-Ligand Interactions. Enzymatic Catalysis
£80.74
Taylor & Francis Inc Printed Resonant Periodic Structures and Their
Book SynopsisThis book is a reference for researchers who want to learn about resonant periodic structures for applications in microstrip circuits. The readers can learn simple methods to analyze these structures using commercially available software and equivalent circuit modelling. The application examples demonstrated in the book will open up new research ideas in this field.Table of ContentsIntroduction to Periodic Structures in Electromagnetics. Planar Periodic Structures as Electromagnetic Bandgap (EBG) Surfaces. Compact Planar Periodic Structure as Band-Rejection Filter. Reconfigurable Periodic Structures. Application of Compact Planar Periodic Structure in Bandpass Filters and Diplexers. Frequency Selective Surface (FSS) Application.
£120.00
Taylor & Francis Inc Introduction to Engineering Materials
Book SynopsisDesigned for the general engineering student, Introduction to Engineering Materials, Second Edition focuses on materials basics and provides a solid foundation for the non-materials major to understand the properties and limitations of materials. Easy to read and understand, it teaches the beginning engineer what to look for in a particular material, offers examples of materials usage, and presents a balanced view of theory and science alongside the practical and technical applications of material science.Completely revised and updated, this second edition describes the fundamental science needed to classify and choose materials based on the limitations of their properties in terms of temperature, strength, ductility, corrosion, and physical behavior. The authors emphasize materials processing, selection, and property measurement methods, and take a comparative look at the mechanical properties of various classes of materials. Chapters include discussions of atomic structure and bonds, imperfections in crystalline materials, ceramics, polymers, composites, electronic materials, environmental degradation, materials selection, optical materials, and semiconductor processing. Filled with case studies to bring industrial applications into perspective with the material being discussed, the text also includes a pictorial approach to illustrate the fabrication of a composite. Consolidating relevant topics into a logical teaching sequence, Introduction to Engineering Materials, Second Edition provides a concise source of useful information that can be easily translated to the working environment and prepares the new engineer to make educated materials selections in future industrial applications.Table of ContentsIntroduction, Properties and Their Measurement, Atomic Structure and Atomic Bonds, Structure of Crystalline Solids, Diffusion and Plastic Deformation, Property Management of Metallic Materials, Ceramics, Structure and Properties of Polymers, Composites, Electrical Properties of Materials, Magnetic Materials, Optical Materials, Semiconductor Processing, Environmental Degradation of Engineering Materials, Materials and Process Selection, Ferrous and Nonferrous Metals for Special Applications, Comparative Properties, Index
£145.00
Taylor & Francis Inc Mechanics of Elastic Composites
Book SynopsisThis is a comprehensive, reader-friendly treatment of the theory behind modern elastic composite materials. The treatment includes recently developed results and methods drawn from research papers published in Eastern Europe that until now were unavailable in many western countries. Among the book's many notable features is the inclusion of more than 400 problems, many of which are solved at the end of the book. Mechanics of Elastic Composites is an outstanding textbook for graduate-level course work and a valuable reference for engineers and researchers. Developed over many years by leading experts in the field, this book will remain an important contribution to the literature for years to come.Table of ContentsList of Figures, Chapter 1 ELEMENTS OF TENSOR CALCULUS, Chapter 2 ELEMENTS OF LINEAR ELASTOSTATICS, Chapter 3 COMPOSITE LAMINATES, Chapter 4 MACROSCOPICALLY ELASTIC COMPOSITES, Chapter 5 THETHREE-DIMENSIONALLINEARIZED THEORY, Chapter 6 BUCKLING OF COMPOSITE STRIPS ANDBARS, Chapter 7 STABILITY OF COMPOSITE LAMINATES, Chapter 8 FRACTURE MECHANICS, SOLUTIONS TO SOME PROBLEMS
£190.00
Apple Academic Press Inc. The Science of Nanomaterials: Basics and
Book SynopsisNanoparticles have a smaller size as compared to their micro, macro, or bulk counterparts. Reduction in size of these particles provides them with some unique characteristics, such as surface-to-volume ratio, quantum confinement effect, surface plasmon response, widening of band gap, etc. These nanoparticles have attracted attention of scientists all over the globe in last few decades.Written in a convenient and easy-to-read style, this book covers the important aspects of nanomaterials by focusing on the many issues related to the food and textile industries, treatment of polluted water, health, energy crises, targeted drug delivery, etc. The editors take an interdisciplinary approach to discussing how the scenario will change on a global level in the future and explore when these nanomaterials will replace almost all micro- and macromaterials.The Science of Nanomaterials is a ready-at-hand guide to the many issues related to the use of nanomaterials in drug and gene delivery, sensors, photosplitting of water, wastewater treatment, microbial diagnosis, textile industries, nanocomposites, food industries (safety, security, packaging and preservation), etc.Table of Contents1. Nanomaterials: An Introduction 2. Optical Properties of Nanostructured Materials and Their Sensing Applications 3. Nanotechnology for Selective Targeting and Cancer Drug Delivery 4. Cogent and Strategic Approaches for Gene Delivery with Nanostructures 5. Nanomaterials for Nanomedical and Nanobiotechnological Studies: Current Status and Applications of Carbon-Based Nanomaterials and Quantum Dots 6. Carbon Nanotubes for Photosplitting of Water 7. Nanomaterials as Effective Tools for Detection and Microbial Diagnosis of Foodborne Pathogens 8. Use of Nanomaterials in Wastewater Treatment 9. Layer-by-Layer Assembly as a Powerful Nanofabrication Technique for the Design of Antimicrobial Surfaces in the Textile Industry 10. Prospect of Utilizing Novel Nanomaterials for Effective Food Security, Safety, Packaging, and Preservation 11. Bio- and Synthetic Nanocomposites for Food Packaging 12. Fabrication and Applications of Nanocomposites
£132.30
Colourpoint Creative Ltd Life and Health Sciences for CCEA AS Level:
Book SynopsisThis updated edition addresses the examined units of the CCEA AS level Life and Health Sciences specification (including the recently-proposed revisions). It covers both the Single and Double Award courses, through the study of the following units:• AS 2: Human Body Systems• AS 3: Aspects of Physical Chemistry in Industrial Processes• AS 5: Material ScienceThe full-colour, illustrated chapters clearly explain the theory for the course, and are supported by worked examples, tips, examination-style questions and answers.The authors are all experienced science teachers and examiners and the book has been through a meticulous quality assurance process prior to publication. Contents: Unit AS 2: Human Body Systems1 Cardiovascular System2 Respiratory System 3 Respiration4 Homeostatic Mechanisms and How These Are Monitored5 Nutrition and Physical Exercise in Maintaining Good HealthUnit AS 3: Aspects of Physical Chemistry in Industrial Processes6 Chemical Calculations7 Volumetric Analysis 8 Energetics9 Kinetics 10 Equilibrium11 Industrial Processes, Infrastructure and Environmental ConsequencesUnit AS 5: Material Science12 Material Properties13 Categorising Materials and Microscopic Structure14 Alloys, Metal Working and Biomaterials15 Smart Materials, Nanomaterials and Industrial Considerations16 Semiconductors Answers Table of ContentsContents: Unit AS 2: Human Body Systems1 Cardiovascular System2 Respiratory System 3 Respiration4 Homeostatic Mechanisms and How These Are Monitored5 Nutrition and Physical Exercise in Maintaining Good HealthUnit AS 3: Aspects of Physical Chemistry in Industrial Processes6 Chemical Calculations7 Volumetric Analysis 8 Energetics9 Kinetics 10 Equilibrium11 Industrial Processes, Infrastructure and Environmental ConsequencesUnit AS 5: Material Science12 Material Properties13 Categorising Materials and Microscopic Structure14 Alloys, Metal Working and Biomaterials15 Smart Materials, Nanomaterials and Industrial Considerations16 Semiconductors Answers
£20.98
Maney Publishing Marine Corrosion of Stainless Steels: Testing,
Book Synopsis
£139.06
Springer Nature Switzerland AG Methods and Applications of Sample Size
Book SynopsisThis book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Appropriate calculation of the required sample size is crucial for the success of clinical trials. At the same time, a sample size that is too small or too large is problematic due to ethical, scientific, and economic reasons. Therefore, state-of-the art methods are required when planning clinical trials. Part I describes a general framework for deriving sample size calculation procedures. This enables an understanding of the common principles underlying the numerous methods presented in the following chapters. Part II addresses the fixed sample size design, where the required sample size is determined in the planning stage and is not changed afterwards. It covers sample size calculation methods for superiority, non-inferiority, and equivalence trials, as well as comparisons between two and more than two groups. A wide range of further topics is discussed, including sample size calculation for multiple comparisons, safety assessment, and multi-regional trials. There is often some uncertainty about the assumptions to be made when calculating the sample size upfront. Part III presents methods that allow to modify the initially specified sample size based on new information that becomes available during the ongoing trial. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses. The application is illustrated using numerous clinical trial examples, and software code implementing the methods is provided. The book offers theoretical background and practical advice for biostatisticians and clinicians from the pharmaceutical industry and academia who are involved in clinical trials. Covering basic as well as more advanced and recently developed methods, it is suitable for beginners, experienced applied statisticians, and practitioners. To gain maximum benefit, readers should be familiar with introductory statistics. The content of this book has been successfully used for courses on the topic.Trade Review“The R source code is shown by chapter, well-documented, and easy to find and follow as brief descriptions and necessary specifications for the function calls are given by means of comments. … a wide area of application fields is covered and exhaustive literature references for further reading are given. … The presentation of the material is very reader-friendly, easily accessible and pedagogical … . It is likewise highly recommended … . This is an effective and nicely written reference textbook.” (Oke Gerke, ISCB News, iscb.info, Vol. 72, December, 2021)Table of ContentsPart I Basics 1 Introduction 1.1 Background and outline 1.2 Examples 1.2.1 The ChroPac trial 1.2.2 The Parkinson trial 1.3 General considerations when calculating sample sizes 2 Statistical test and sample size calculation 2.1 The main principle of statistical testing 2.2 The main principle of sample size calculation Part II Sample size calculation 3 Comparison of two groups for normally distributed outcomes and test for difference or superiority 3.1 Background and notation 3.2 z-test 3.3 t-test 3.4 Analysis of covariance 3.5 Bayesian approach 3.5.1 Background 3.5.2 Methods 4 Comparison of two groups for continuous and ordered categorical outcomes and test for difference or superiority 4.1 Background and notation 4.2 Continuous outcomes 4.3 Ordered categorical outcomes 4.3.1 Assumption-free approach 4.3.2 Assuming proportional odds 5 Comparison of two groups for binary outcomes and test for difference and superiority 5.1 Background and notation 5.2 Asymptotic tests 5.2.1 Difference of rates as effect measure 5.2.2 Risk ratio as effect measure 5.2.3 Odds ratio as effect measure 5.2.4 Logistic regression 5.3 Exact unconditional tests 5.3.1 Background 5.3.2 Fisher-Boschloo test 6 Comparison of two groups for time-to-event outcomes and test for differences or superiority 6.1 Background and notation 6.1.1 Time-to-event data 6.1.2 Sample size calculation for time-to-event data 6.2 Exponentially distributed time-to-event data 6.3 Time-to-event data with proportional hazards 6.3.1 Approach of Schoenfeld 6.3.2 Approach of Freedman 7 Comparison of more than two groups and test for difference 7.1 Background and notation 7.2 Normally distributed outcomes 7.3 Continuous outcomes 7.4 Binary outcomes 7.4.1 Analysis with chi-square test 7.4.2 Analysis with Cochran-Armitage test 7.5 Time-to-event outcomes 8 Comparison of two groups and test for non-inferiority 8.1 Background and notation 8.2 Normally distributed outcomes 8.2.1 Difference of means 8.2.2 Ratio of means 8.3 Continuous and ordered categorical outcomes 8.4 Binary outcomes 8.4.1 Analysis with asymptotic tests 8.4.1.1 Difference of rates as effect measure 8.4.1.2 Risk ratio as effect measure 8.4.1.3 Odds ratio as effect measure 8.4.2 Exact unconditional tests 8.4.2.1 Background 8.4.2.2 Difference of rates as effect measure 8.4.2.3 Risk ratio as effect measure 8.4.2.4 Odds ratio as effect measure 8.5 Time-to-event outcomes 9 Comparison of three groups in the gold standard non-inferiority design 9.1 Background and notation 9.2 Net effect approach 9.3 Fraction effect approach 10 Comparison of two groups for normally distributed outcomes and test for equivalence 10.1 Background and notation 10.2 Difference of means 10.3 Ratio of means 11 Multiple comparisons 11.1 Background and notation 11.2 Generally applicable sample size calculation methods and applications 11.2.1 Methods 11.2.2 Applications 11.3 Multiple endpoints 11.3.1 Background and notation 11.3.2 Methods 11.4 More than two groups 11.4.1 Background and notation 11.4.2 Dunnett test 12 Assessment of safety 12.1 Background and notation 12.2 Testing hypotheses on the event probability 12.3 Estimating the occurrence probability of an event with specified precision 12.4 Observing at least one event 13 Cluster-randomized trials 13.1 Background and notation 13.2 Normally distributed outcomes 13.2.1 Cluster-level analysis 13.2.2 Individual-level analysis 13.2.3 Dealing with unequal cluster size 13.3 Other scale levels of the outcome 14 Multi-regional trials 14.1 Background and notation 14.2 Sample size calculation for demonstrating consistency of global results and results for a specified region 14.3 Sample size calculation for demonstrating a consistent trend across all regions 15 Integrated planning of phase II/III drug development programs 15.1 Background and notation 15.2 Optimizing phase II/III programs 16 Simulation-based sample size calculation Part III Sample size recalculation 17 Background Part IIIA Blinded sample size recalculation in internal pilot study designs 18 Background and notation 19 A general approach for controlling the type I error rate for blinded sample size recalculation 20 Comparison of two groups for normally distributed outcomes and test for difference or superiority 20.1 t-Test 20.1.1 Background and notation 20.1.2 Blinded variance estimation 20.1.3 Type I error rate 20.1.4 Power and sample size 20.2 Analysis of covariance 20.2.1 Background and notation 20.2.2 Blinded variance estimation 20.2.3 Type I error rate 20.2.4 Power and sample size 21 Comparison of two groups for binary outcomes and test for difference or superiority 21.1 Background and notation 21.2 Asymptotic tests 21.2.1 Difference of rates as effect measure 21.2.2 Risk ratio and odds ratio as effect measure 21.3 Fisher-Boschloo test 22 Comparison of two groups for normally distributed outcomes and test for non-inferiority 22.1 t-Test 22.1.1 Background and notation 22.1.2 Blinded variance estimation 22.1.3 Type I error rate 22.1.4 Power and sample size 22.2 Analysis of covariance 23 Comparison of two groups for binary outcomes and test for non-inferiority 23.1 Background and notation 23.2 Difference of rates as effect measure 23.3 Risk ratio and odds ratio as effect measure 24 Comparison of two groups for normally distributed outcomes and test for equivalence 25 Regulatory and operational aspects 26 Concluding remarks Part IIIB Unblinded sample size recalculation in adaptive designs 27 Background and notation 27.1 Group-sequential designs 27.2 Adaptive designs 27.2.1 Combination function approach 27.2.2 Conditional error function approach 28 Sample size recalculation based on conditional power 28.1 Background and notation 28.2 Using the interim estimate of the effect 28.3 Using the initially specified effect 28.4 Using prior information as well as the interim effect estimate 29 Sample size recalculation by optimization 30 Regulatory and operational aspects 31 Concluding remarks Appendix: Selected R software code References
£49.49
Springer Nature Switzerland AG Paths to Leadership in the Senior Living Industry
Book SynopsisThis book assembles many of the great leaders of the senior living and care industry to discuss their paths to and views on leadership. Each chapter provides readers with ideas, information, and inspiration on how to achieve leadership in this dynamic, mission-focused industry. It includes various strategies for success, such as promoting meaning and purpose in corporate culture, making decisions in the absence of perfect information, managing your personal assets of relationships and reputation, and finding competitive advantages through technology, training, and team-building. These leaders also share their experiences responding to COVID-19 and discuss how the pandemic may change the future of leadership in the industry. Whether your path starts in gerontology, nursing, social work, design, real estate, finance, law, operations, or technology, and whether one pursues work in the private, nonprofit, or government sectors, this volume provides a valuable resource for all aspiring and developing leaders in the senior living industry.Table of ContentsChapter 1. Introduction.- Chapter 2. How an Innovator Thinks: Applied Evangelism.- Chapter 3. The Founder.- Chapter 4. Pioneer in Assisted Living.- Chapter 5. A Revolutionary in Aging.- Chapter 6. Changing the World: From Government to Assisted Living.- Chapter 7. Memory Care Futurist.- Chapter 8. From Pro Athlete to Senior Living to Pro Sports. Chapter 9. Leading the Way, South of the Border.- Chapter 10. Competition channeled into Leadership. Chapter 11. A Social Entrepreneur.- Chapter 12. Hippie at the Helm.- Chapter 13. Breaking the Mold.- Chapter 14. Innovating Senior Living.- Chapter 15. Making Decisions Without All the Information.- Chapter 16. Marketing My Way into Senior Living.- Chapter 17. Transforming an Organization.- Chapter 18. Financial Leadership.
£49.49
Springer Nature Switzerland AG Valvular Heart Disease: A Guide for Cardiovascular Nurses and Allied Health Professionals
Book SynopsisThis book serves as the “go-to” resource for cardiovascular nurses and other health care practitioners involved in the care of patients with acquired valvular heart disease. It includes unique information about heart valve anatomy and pathophysiology, the complexity of clinical presentations and diagnostic evaluation, patient education and shared decision-making, surgical and transcatheter treatment options, and transition to palliative care. The content focuses primarily on the specialized care of patients with aortic stenosis and regurgitation, and mitral and tricuspid regurgitation. In addition, this unique resource provides timely information to guide a patient-centred and team-driven approach that reflects contemporary and innovative practice in the management of valvular heart disease. The essential topics of strengthening the multidisciplinary Heart Team and programmatic processes of care, the priorities for nursing care, and the multifactorial challenges of managing this complex patient population are explored in detail. Importantly, this resource aims to support all clinicians who are involved in the various timepoints of patients’ full trajectory of care, from their evaluation pathway, admissions for treatment, and long term follow-up. Clinicians require contemporary knowledge and evidence to guide their practice, provide appropriate care for this complex patient population, and contribute to the advancement of practice. To date, there has been little emphasis placed on the management of valvular heart disease in cardiovascular nursing and allied health curriculum. This book fills this gap and addresses the pressing need for a user-friendly resource to guide the care for this growing population in a rapidly changing clinical environment. The editors are international leaders in the care and management of patients with acquired valvular heart disease and program development. They are widely recognized for their pioneering role in shaping the way we care for these patients. Table of ContentsChapter 1: Introduction and ObjectivesM. Hawkey, S. Lauck • Nursing practice in the setting of VHD – Roles and responsibilities of nurses caring for patients with VHD• Recent developments in the treatment of VHD; expanded role of nursing in this area of care delivery• Gap that this book fills• Objectives, target audience and contentSection 1: Understanding Valvular Heart DiseaseChapter 2: Overview of Patient PopulationM. Hawkey, B. Hojberg Kirk • Prevalence/epidemiology of VHD• Patients’ experiences of disease trajectory• Clinical presentation(s) and areas of nursing practice where patients present• Special considerations: o VHD in older patients o VHD in younger patients o Patients with multiple VHD o The impact of concomitant diseases Chapter 3: Pathophysiology of Valvular Heart DiseaseE. Perpetua • Brief review of anatomy and physiology• Aortic stenosis• Aortic regurgitation• Mitral regurgitation• Tricuspid regurgitation• Pulmonary stenosis• EndocarditisSection 2: Valvular Heart Disease Program StructureChapter 4: The Multidisciplinary Heart Team ApproachS. Lauck• Origins, rationale and evidence supporting the MDT in the treatment of VHD• Membership, roles and responsibilities; the role and contributions of nursing leadership in promoting a MDT approac• Examples of models of MDT “in action”• The role of a palliative approach in the MDT model• Considerations of MDT treatment decision and procedure planning• Challenges and limitationsChapter 5:Processes of Care for Valvular Heart Disease ProgramsM. Speight• Organization and components of patient pathway from referral to follow-up• The role of the Valve Program Clinician• Examples of models of processes of care: Heart valve clinic vs. “procedure-based” referral programs• Patient pathway o Screening, evaluation, patient teaching and treatment decision o Peri-procedure processes o Post-procedure processes o Follow-up processesSection 3: Assessing Valvular Heart Disease Chapter 6: Clinical AssessmentJ. Munoz• Clinical consultations and assessmentsChapter 7: Imaging ModalitiesR. Brandwein• Diagnostic imaging: o Cardiac echocardiography (TTE and TEE) o Computed tomography o Cardiac catheterization o Magnetic resonance imaging• Risk scores for the treatment of VHDChapter 8: Understanding Function, Frailty and Self-Reported Health StatusT. Norekval• Functional status• Frailty and its implications for treatment decision and post-procedure care• Patient-reported outcomesChapter 9: Making a High Quality Treatment Decision: Shared Decision-MakingR. Palmer• Shared decision-making• Patient decision aids• Challenges and limitations of implementationSection 4: Treatment Options for Valvular Heart Disease and Implications for NursingChapter 10: Surgical TreatmentB. Borregaard• Surgical techniques• Need to completeChapter 11: Transcatheter TreatmentS. LauckA. Smith Section 5: Nursing Care Priorities Valvular Heart Disease Chapter 12: Safe Recovery after Valvular Heart SurgeryP. Keegan Chapter 13: Safe Recovery after Transcatheter Heart Valve ProceduresJ. Wyman Chapter 14:Transitions of Care and Long Term Follow-Up after Heart Valve Surgery and Transcatheter ProceduresN. StraitonChapter 15: Conclusion: The Next Decade of Treating Valvular Heart Disease – An Opportunity for Nursing LeadershipM. Hawkey, S. Lauck International authorship: Hackensack, NJ, USA, Sydney, AU, Copenhagen, DE, Bergen, NO, Seattle, WA, USA, San Francisco, CA, USA, New York, NY, USA, Vancouver, BC, Canada, Lebanon, USA
£999.99
Springer Nature Switzerland AG Exocrinology: A Textbook and Atlas of the
Book SynopsisThis is the first textbook solely dedicated to the study of exocrine glands and cells throughout the human body. Students will gain a broad overview of the whole exocrine system, it’s structural features and learn to understand it’s integral parts in almost all bodily functions. Taking a systemic approach, the author guides readers through the different organ sites, shapes, methods of secretion and their secretory products. Starting with the glands of the integument, which is covering the outside of the body, the chapters proceed to also discuss the urinary tract, respiratory, digestive and reproductive systems. Various levels of complexity, from single goblet cells to the major organs, are thoroughly explained. A basic knowledge in histology is advantageous, for the numerous and rich illustrations. With its inviting writing style, this textbook is a perfect learning tool for students in Physiology and Medicine – particularly considering Dentistry, Dermatology, Gastroenterology and Pulmonology.Table of ContentsTABLE OF CONTENTS List of Figures…………………………………………..………………xi List of Tables…………………………………………………………... xii Acknowledgements……………………………………………………..xiv Preface…………………………………………………………………...v List of Acronyms……………………………………………………….xii Chapter 1 Introduction to Exocrinology 1.1 Gland 1.2 Types of Exocrine glands Chapter 2 Exocrine Glands of the Integument 2.1 Introduction 2.2 Basic Histology of the Integumentary System 2.3 Glands of the Integument Chapter 3 Exocrine Glands of the Respiratory System 3.1 Introduction 3.2 Anatomy and Histology of the Nasal Cavity 3.3 Paranasal Sinuses 3.4 The Nasopharynx, Oropharynx and Larynx 3.5 Respiratory System Chapter 4 Exocrine Glands of the Alimentary Tract System Section Part I 4.1 Introduction 4.2 Exocrine Glands of the Lips 4.3 Exocrine Glands of the Hard Palate 4.4 Exocrine Glands of the Tongue 4.5 The Major Salivary Glands Chapter 5 Exocrine Glands of the Alimentary Tract System Section Part II 5.1 Introduction 5.2 Esophagus 5.3 Stomach 5.4 Small Intestines 5.5 Large Intestines 5.6 Rectum and Anal Canal Chapter 6 Exocrine Glands of the Alimentary Tract System Section III 6.1 Introduction 6.2 Pancreas 6.3 Liver 6.4 Gall Bladder Chapter 7 Exocrine Glands of the Reproductive System 7.1 Introduction Chapter 8 Exocrine Glands of the Urinary system 8.1 Introduction 8.2 The Exocrine Kidney 8.3 Ureters 8.4 Bladder 8.5 Urethra 8.6 UrineChapter 9 Exocrine Glands of the Sensory Organs 9.1 The Ear 9.2 The Eye 9.3 Glands of the nose and tongue Index
£54.99
Springer International Publishing AG Modern Biostatistical Methods for Evidence-Based
Book SynopsisThis book provides an overview of the emerging topics in biostatistical theories and methods through their applications to evidence-based global health research and decision-making. It brings together some of the top scholars engaged in biostatistical method development on global health to highlight and describe recent advances in evidence-based global health applications. The volume is composed of five main parts: data harmonization and analysis; systematic review and statistical meta-analysis; spatial-temporal modeling and disease mapping; Bayesian statistical modeling; and statistical methods for longitudinal data or survival data. It is designed to be illuminating and valuable to both expert biostatisticians and to health researchers engaged in methodological applications in evidence-based global health research. It is particularly relevant to countries where global health research is being rigorously conducted.Table of Contents1. Harmonization of Longitudinal Population Data: evidence from three rural health and demographic surveillance system nodes in South Africa.- 2. Adjusting for Selection Bias in Assessing the Efficacy of Health Inputs on Birth Outcome: Evidence from South-Saharan Africa.- 3. An Indirect Assessment of the Effect of Anthropogenic Activities on the Ecology of the Intermediate Snail Host for Schistosoma Haematobium.- 4. Diagonal Reference Modeling of Effects of Couples' Educational Differences on Women's Health Care Utilization in Sub-Saharan Africa - Gebrenegus Ghilagaber, Michael Carlson.- 5. Sequential Modeling of Parity Progression Ratios in Sub-Saharan Africa.- 6. Evidence-informed Public Health, Systematic Reviews, and Meta-analysis.- 7. Meta-analysis Methods and Empirical Comparison of Aggregate Data and Individual Participant Data Results from Sample Survey Data.- 8. Statistical Meta-analysis and its Efficience Between Summary Statistics and Individual Participant-level Data: A Monte-Carlo simulation study.- 9. Multivariate Disease Mapping for Multiple Health Outcomes.- 10. Measuring Spatial Dependence of Non-communicable Diseases in South Africa.- 11. Mapping Health Outcomes in Sub-Saharan African Region Using Survey Data, Adjusting for Survey Data - Sheyla Rodrigues Cassy.- 12. Spatial Multi-criteria Decision Analysis in Health Sciences: Fifteen years of applications and trends.- 13. Estimating Determinants of Stage at Diagnosis of Breast Cancer Prevalence in Western Nigeria Using Bayesian Logistic Regression.- 14. Dynamic Bayesian Adjustment of Educational Gradients in Divorce Risks: Disentangling causation and misclassification.- 15. Bayesian Dynamic Models for Time-Varying Outcomes: Applications to a patient cohort on ART.- 16. Suicide Ideation and Associated Factors Among School-going Adolescents in Namibia: A Multilevel logistic regression.- 17. Bayesian Inference in the Extended Generalized Gamma Model and its Special Cases: With applications on demographic and health survey data from Sub-Saharan Africa.- 18. Changing Effects of Covariates on Childhood Mortality in Sub-Saharan Africa: A dynamic Bayesian survival modeling approach.- 19. Group Outliers and Influence Assessments in Clustered Survival Data Modeling.- 20. Joint Modeling of Competing Risks Survival and Longitudinal Data
£131.50
Springer International Publishing AG The Centrosome and its Functions and Dysfunctions
Book SynopsisThe book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases. In addition, several chapters raise awareness of centrosomes in areas that have not yet fully considered the centrosome as an organelle that impacts other organelle functions directly or indirectly. It further relates centrosome functions to other research areas such as aging and stem cell research. Since its discovery almost 150 years ago the centrosome is increasingly being recognized as a most impactful organelle for its role, not only as primary microtubule organizing center (MTOC) but also as a major communication center for signal transduction pathways and as a center for proteolytic activities. Its significance for cell cycle regulation has been well studied and we now also know that centrosome dysfunctions are implicated in numerous diseases and disorders including cancer, cystic diseases of the kidney, liver fibrosis, cardiac defects, obesity and several other diseases and disorders. This new volume reviews the latest advances in the field and provides valuable background information that is readily understandable for the newcomer and the experienced centrosome researcher alike. Due to the interdisciplinary of the subject, it is a valuable resource for researchers and clinicians working in biomedical research, cell biology, cancer biology, reproduction and developmental biology, neuroscience and stem cell research. Table of ContentsIntroduction 1) Cell and Molecular Biology of Centrosome Structure and Function 1.1 Historical Perspectives 1.2 Centrosome Structure, Molecular Composition, and Function 1.3 Centrosome Matrix and Centrosomal Proteins Centrosome Proteins 1.4 Centriole Structure and Cell Cycle-specific centriole dynamics 1.5 In vivo imaging of Centrosomes 2) The centrosome Cycle within the cell cycle 2.1 Centrosome-nuclear interactions 2.2 Centrosome maturation, mitosis and cell division this all needs sorting 2.3 Chromosome (DNA)-centrosome synchronization cycle - this all needs sorting 2.4 Centrosome-Golgi relationships and interconnected functions 2.5 Primary cilia 3) Centrosome as center for proteolytic activity and dysfunctions associated with pathogenesis of human disease 3.1 Centrosomes as center for proteolytic activity and dysfunctions in disease 3.2 Other centrosome-related dysfunctions in disease 3.3 Vesicular transport dysfunctions and disease 3.4 Basal body dysfunctions and disease 4) Centrosome dysfunctions in cancer Needs sorting - Viral transformation and aneuploidy - Oncogenes and tumor suppressor genes - Centrosomes as targets for cancer therapy 5) Virus exploitation of centrosomes 6) Centrosomes in reproduction Introduction 6.1 The importance of choosing an appropriate animal model 6.2 Centrosome terminology questions in reproductive cells 6.3 Centrosome reduction during gametogenesis 6.4 The Sperm Centriole Complex Before Fertilization 6.5 Centrosomes in unfertilized eggs and oocytes 6.6 Centrosomes during oocyte maturation, fertilization and first cell division - oocyte maturation - fertilization and first cell division 6.7 Effects of aging on oocyte centrosomes (something like this) 7) Transition from centrosomal to non-centrosomal microtubule organization during cellular polarization 8) External and environmental effects on Centrosomes 8.1 Effects of ionizing radiation on centrosomes 8.2 Environmental and genotoxic stress on centrosomes 9) Centrosomes and centrosome equivalents in other systems 9.1 Stem cells 9.2 Neuronal cells 9.3 T cells (cytotoxic T-lymphocytes; CTLs) 9.4 Centrosomes and centrosome equivalents in other systems and in model organisms - Parasites - Yeast (spindle pole bodies; SPBs) - Dictyostelium (nuclear associated bodies; SPBs) - C elegans - Drosophila 10) Non-centrosomal microtubule organization in plant cells
£999.99
Springer Sciencegramers
a huge range and FREE tracked UK delivery on ALL orders.
£29.69
Springer International Publishing AG You Must Be Very Intelligent: The PhD Delusion
Book SynopsisYou Must be Very Intelligent is the author’s account of studying for a PhD in a modern, successful university. Part-memoir and part-exposé, this book is highly entertaining and unusually revealing about the dubious morality and desperate behaviour which underpins competition in twenty-first century academia. This witty, warts-and-all account of Bodewits´ years as a PhD student in the august University of Edinburgh is full of success and failure, passion and pathos, insight, farce and warm-hearted disillusionment. She describes a world of collaboration and backstabbing; nefarious financing and wasted genius; cosmopolitan dreamers and discoveries that might just change the world… Is this a smart people’s world or a drip can of weird species? Modern academia is certainly darker and stranger than one might suspect… This book will put a wry, knowing smile on the faces of former researchers. And it is a cautionary parable for innocents who still believe that lofty academia is erected upon moral high ground…Trade Review“A new novel about academic life is not a ringing endorsement, to say the least. But it will make you laugh. And that’s the point.” (Colleen Flaherty, Inside Higher Ed, February, 2018)“The story is immersive, and I felt like I was there with our hero every step of the way.” (Chemistry World, chemistryworld.com, January 2018)“Karin Bodewits’ partly autobiographic book ‘You must be very intelligent – The PhD Delusion’ is a revealing, tongue in cheek tale about PhD life.” (Ulrike Träger, Metior Magazine, November, 2017)“PhD novel is ‘wake-up call’ on supervisor-student ‘power plays’” (Times Higher Education, November, 2017)Table of ContentsDedication.- Foreword.- Prologue.- Part I: Before.- Part II: Year 1.- Part III: Year 2.- Epilogue.
£31.34
Springer International Publishing AG Simulation Algorithms for Computational Systems
Book SynopsisThis book explains the state-of-the-art algorithms used to simulate biological dynamics. Each technique is theoretically introduced and applied to a set of modeling cases. Starting from basic simulation algorithms, the book also introduces more advanced techniques that support delays, diffusion in space, or that are based on hybrid simulation strategies.This is a valuable self-contained resource for graduate students and practitioners in computer science, biology and bioinformatics. An appendix covers the mathematical background, and the authors include further reading sections in each chapter.Trade Review“I will not hesitate to recommend … this book, both as an introductory explanation as well as later on when they are deep in a modeling exercise and need to understand the many subtle yet important variations of stochastic simulation techniques applicable to biological systems.” (Sara Kalvala, Computing Reviews, March, 2018)Table of ContentsIntroduction.- Deterministic Simulation Algorithms.- Stochastic Simulation Algorithms.- Hybrid Simulation Algorithms.- Reaction-Diffusion Systems.- Conclusions and Perspectives.
£999.99
Springer International Publishing AG From Aardvarks to Zooxanthellae: The Definitive
Book SynopsisHundreds of animal species provide the cast of characters for these newly composed bio-limericks, arranged into 17 chapters by taxonomic group (such as Birds, Fishes, Insects) or biological subject (such as Ecology, Genetics, and Anthropology). Sometimes multiple verses on one organism or topic provide an extended story-line across successive poems. In addition, several stylistic vignettes recur throughout the book, such as: (a) “On the Farm”, which ranges from barnyards to fish farms to oyster farms; and (b) “Let’s Play Jeopardy”, where the reader guesses an animal from poetic clues the author provides. Each little jingle can be read as a stand-alone offering a quick chuckle or biological insight. But watch out—these poetic tidbits can be as addictive as popcorn, such that some readers will feel compelled to consume each chapter and indeed the entire book at one sitting! Covering nearly every creature that any amateur or professional biologist has ever heard of, these pun-filled limericks provide humorous insight into each critter or its peculiar habits, in a sharply witty and cutely informative way. Table of ContentsMammalogy (mammals)Ornithology (birds)The Life of a Couple of BirdsHerpetology (reptiles and amphibians)Ichthyology (fishes)The Life of a FishEntomology (insects)Invertebrate Zoology (other than insects)Microbiology (microbes)Botany (plants)Anatomy, Physiology, and MedicineEcologyEthology (behavior)EvolutionGeneticsAnthropology: The Human SagaAppendix: Famous Animal Phrases
£999.99
Springer International Publishing AG Cardiac Regeneration
a huge range and FREE tracked UK delivery on ALL orders.
£999.99
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Chemicals for Life and Living
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£23.74
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Mood Matters: From Rising Skirt Lengths to the
Book Synopsis"Mood Matters" makes the radical assertion that all social events ranging from fashions in music and art to the rise and fall of civilizations are biased by the attitudes a society holds toward the future. When the "social mood" is positive and people look forward to the future, events of an entirely different character tend to occur than when society is pessimistic. The book presents many examples from every walk of life in support of this argument. In addition, methods are given to actually measure the social mood and to project it into the future in order to forecast what’s likely or not over varying periods of time. Casti's writing is a pleasure to read and its contents an eye-opener."They [the chapters] tell an engrossing story, and the mystery heightens as it goes. . . . it's chatty and knowing." Greg Benford, Physicist and science-fiction writer, author of "Timescape" and "Deep Time""I am struck by how thought-provoking it all is. I am sure that your book will draw a lot of attention" Tor Norretranders, Science writer, author of "The Generous Man" and "The User Illusion". Trade ReviewFrom the reviews:"They [the chapters] tell an engrossing story, and the mystery heightens as it goes. . . . it's chatty and knowing." Greg Benford, Physicist and science-fiction writer, author of "Timescape" and "Deep Time""I am struck by how thought-provoking it all is. I am sure that your book will draw a lot of attention" Tor Norretranders, Science writer, author of "The Generous Man" and "The User Illusion".“This is John Casti’s bold hypothesis in Mood Matters, which challenges both traditional financial theory and human gut reaction about how the world works. … The wealth of facts he presents should serve as valuable fuel for future scientific researchers arguing both for and against socionomics. In these times of financial turmoil, many people will pick up Mood Matters with the hope of predicting financial markets. … The book emphasizes the importance of sociometers in signaling that fate.” (Richard Taylor, Science, Vol. 329, September, 2010)“Readable, exhaustively researched, and completely iconoclastic, this book was a pleasure for me on many levels. I am always eager to hear about new ways to view this old world, and Casti has a very new way to view world events. His thesis is that the mood of the people isn’t MADE by events, but … MAKES events. … The exhaustive research I mentioned is all documented in his appendices.” (Richard Derus, LibraryThings, October, 2010)“In Mood Matters (2010) John Casti says a lot of things … about how ones attitude (mood) shapes events, and how we cycle back and forth between pessimism and optimism (mood). … a thought provoking book.” (LibraryThing, August, 2010)“Mood Matters is great fun to read as Casti’s writing throughout is smooth, intelligent and humorous. … Casti explores the correlation between the ‘mood of the crowd’ and a range of other trends … and events, including the fall of nations and the outbreak of war. It is a hugely interesting and wide-ranging study. … For those involved in assessing trends and in predicting future events, whether social, political or economic, this book … change the whole way they ply their trade.” (Goodreads, August, 2010)“John Casti … offers a truly unique and different perspective of why things happen – in our lives, in our world, and in our political systems. … I find John’s views of external events to be fresh and interesting … . he gives a very interesting view of how social influences indirectly – yet directly – impact the economic well-being of our society … . John has done a really nice job … . Mood Matters is a very well-written book, very detailed, and very thorough.” (Abraham Aizenman, TodayNewsline, February, 2011)Table of ContentsIntroducing Unconventional Wisdom.- Why 'Stuff Happens.-Why Hits Happen (short timescale events).-Why Wars, Elections, and Economic Crises Happen(medium timescale events).- Why Great Powers Come and Go (long timescale events).- How to Forecast Coming Events.-
£23.51
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Platelet Aggregation in the Pathogenesis of Cerebrovascular Disorders: Proceedings of the Round Table Conference. Rome, October 30 – 31, 1974
Table of ContentsIntroductory Remarks.- Methodology and Physiology Chairmen: G.V.R. Born and K. Breddin.- The Platelet as an Inflammatory Cell.- Platelet Aggregation in the Pathogenesis of Cerebrovascular Disorders.- The Mathematical Analysis of the Human Platelet Aggregation Mechanism and Its Clinical Application.- Quantitative Valuation of Platelet Aggregation Curves through the Calculation of a Numerical Index.- The Polyunsaturated Fatty Acids in Human Platelets: Effects of Diet and Possible Functional Significance.- Enhanced Platelet Aggregation as a Risk Factor for Progress and Complications of Vascular Disease. New Findings with a Platelet Aggregation Test (PAT III) and on the Dependence of Different Aggregation Tests on Morphologic Platelet Changes.- Pathogenesis Chairmen: M. Anthony, T. Abe, E.J. Acheson, J.S. Meyer, J. Marshall, K.J. Zülch.- Thrombosis and Embolism as a Cause of Ischemic Cerebrovascular Disturbances. Analysis from a Series of 1000 Patients.- Platelet Adhesiveness and Cerebral Vascular Disease Revisited.- The Significance of Platelet Aggregation in Amaurosis Fugax.- Mechanisms of Platelet 5-Hydroxytryptamine Release in Migraine.- Experimental observations on Platelet Emboli in Focal Brain Ischemia.- Observations on Platelet Aggregability in the Acute Phase of Untreated Strokes.- Microembolism in the Nervous System.- Influence of Plasma Components in the Development of Conditions of Increased Platelet Aggregation Found in a Number of Vascular Diseases.- Mechanism Associated with Platelet Adhesiveness in Cerebrovascular Disease.- Regional Intravascular Coagulation and Microthrombosis in Traumatic Brain Lacerations in Man.- Platelet Aggregation in Cerebrovascular Patients.- In Vivo Effect of Cyclic AMP and Related Drugs on Platelet Function.- Platelet Hyperreactivity and Decreased Survival in Chronic Cerebrovascular Patients. Chronic Defibrination Syndrome?.- Arterial Hypertension and Platelet Aggregation in the Patho-Pathogenesis of Cerebrovascular Diseases.- Smoking, Cerebrovascular Diseases and Platelet Functions.- Contribution of Platelet Aggregation and Serotonin Release to Progressive Cerebral Infarction.- Effect of Agents which Modify Platelet Aggregation and/or Coagulation on Experimental Platelet Embolism and Intravascular Coagulation.- Platelet Abnormalities in Cerebrovascular Diseases.- Inhibition of Platelet Aggregation by Synthetic Organic Acids: Quantitative Relationships Between Chemical Structures and Biological Activities.- Some Observations of Platelet Changes in Atherosclerosis and Some Observations in the Platelet Alterations Before and After Antiaggregant Drugs in Normal and Atherosclerotics.- Pharmacology and Clinical Pharmacology Chairmen: C.A. Bouvier, W.S. Fields, O.N. Ulutin, A. Rascol.- Inhibition of Platelet Thrombus Formation by Pharmacological Agents.- A Long-Term Clinical Trial with Antiplatelet Agents in Cerebrovascular Ischemia: Biological and Methodological Aspects.- Effect of Aspirin and Dipyridamole on Platelet Function and on Neurologic Evaluation of Patients Affected by Stroke or Transient Ischemic Attacks.- The Pharmacologic Control of the Enhanced Platelet Aggregation in Preventive Neurology.- Aspirin in Cerebral Ischemia.- The Canadian Cooperative Studies of the Effect of Platelet-Suppressing Drugs in Transient Cerebral Ischemic Attacks.- On the Relationships Between the Activation of the Complement System and the Platelet Aggregation.- Discussion and Concluding Remarks.- Chairmen’s Considerations.- Concluding Remarks.
£85.49
Springer Presentation of Data in Science: Publications, slides, posters, overhead projections, tape-slides, television Principles and practices for authors and teachers
Book SynopsisBasic essentials for black-and-white artwork 137 11. 2. 11. 2. 1. Paper 137 11. 2. 2. Pencils 141 11. 2. 3. Inks 142 11. 2. 4. Pens 142 11. 2. 5. Rulers and set squares 143 11. 2. 6. Templates and stencils 143 11. 2. 7. Erasers 144 Scalpels 144 11. 2. S. 11. 2. 9. Burnishers 144 11. 2. 10. Adhesives 152 11. 2. 11. Drafting tape 152 11. 2. 12. Drawing boards 153 11. 3. Other useful items for black-and-white artwork 153 11. 3. 1. Self-adhesive tapes 153 11. 3. 2. Dry-transfer symbols and lettering 154 11. 3. 3. Tone sheets 155 11. 3. 4. 'Pounce' powder 156 11. 3. 5. Fixatives and varnishes 156 11. 4. Additional materials for colour and OHP work 157 11. 4. 1. Self-adhesive colour sheets 157 11. 4. 2. Paints 157 11. 4. 3. Brushes 157 11. 4. 4. Cells and foils (acetate sheets) 158 11. 5. Working comfort 158 11. 5. 1. Organisation 158 11. 5. 2. Furniture 158 11. 5. 3. Lighting 159 12. Basic techniques 160 12. 1. Care and preparation of paper 160 12. 2. Ink work 160 12. 2. 1. Use of technical drawing pens 160 12. 2. 2. Blotting 163 12. 2. 3. Drawing ink lines 163 12. 2. 4. Finishing-off ink lines 165 12. 2. 5. Use of templates and stencils 165 12. 2. 6. Short cuts 165 12. 3. Correcting errors in ink work 167 12. 3. 1.Trade Review`Publish or perish is a cliché, but true and we all take it seriously. As a result the total medical output doubles about every seven years. Some books form important stepping stones to greater production, and easier life and the more efficient use of resources. This book is one to be recommended highly to all who write, lecture and teach.' Journal of the Royal Society of Medicine, 75 (1982) `...one of the most useful practical publications to appear in many a long day. It can be highly recommended.' Journal of the Institute of Health Education, 23:3 `...Departmental Libraries that do not already possess it should add it to their shelves.' Journal of the Royal Society of Medicine, 78 (1985) `Presentation of Data in Science is an excellent book, and every serious research unit producing papers and preparing lectures should have a copy on its shelves - and should use it.' British Medical Journal Table of Contents1. The legibility of type.- 1.1. Introduction.- 1.2. Investigating legibility.- 1.2.1. The reading process.- 1.2.2. Methods of research.- 1.3. Type forms.- 1.3.1. The basic anatomy of type.- 1.3.2. Typeface.- 1.3.3. Type weight.- 1.3.4. Italics.- 1.3.5. Capitals versus lower case.- 1.3.6. Numerals.- 1.4. Type size.- 1.5. Line length.- 1.6. Line spacing.- 1.7. Letter and word spacing.- 1.8. Justified versus unjustified setting.- 1.9. Margins.- 1.10. Single- versus double-column layouts.- 1.11. Paper and ink.- 2. The presentation of text.- 2.1. The visual representation of information ‘structure’.- 2.2. Continuous text.- 2.2.1. Headings.- 2.2.2. Paragraphs.- 2.3. Bibliographies and references.- 2.4. Indexes.- 3. The presentation of tables.- 3.1. Structure.- 3.2. Layout and typography.- 3.2.1. General principles.- 3.2.2. Horizontal emphasis.- 3.2.3. Vertical emphasis.- 3.2.4. Headings.- 3.2.5. Lettering.- 4. The presentation of graphs, charts and diagrams.- 4.1. The relative merits of different kinds of illustration.- 4.2. The content of illustrations.- 4.3. General principles of presentation.- 4.3.1. Layout.- 4.3.2. Framing.- 4.3.3. Visual emphasis.- 4.4. The presentation of graphs and charts.- 4.4.1. Data points.- 4.4.2. Standard errors.- 4.4.3. Lines linking data points.- 4.4.4. Scale calibrations.- 4.4.5. Axes.- 4.4.6. Labelling of axes.- 4.4.7. Keys.- 4.4.8. Headings.- 5. Printed publications.- 5.1. Introduction.- 5.2. Graphic standards for graphs, charts and diagrams in printed journals.- 5.2.1. Instructions to authors.- 5.2.2. Reproduction ratios.- 5.2.3. Size of drafts and artwork.- 5.2.4. Formulae.- A. Capital letter height.- B. Line thickness.- C. Space between ruled lines.- D. Dot diameter.- 5.2.5. Character style.- 5.2.6. Character spacing.- 5.2.7. Space between lines of text.- 5.2.8. Tones and shading.- 5.2.9. Positive versus negative images.- 5.2.10. Contrast.- 5.2.11. Oversize artwork for publication.- 5.2.12. Compatibility with standards for slides.- 5.3. Guide lines for camera-ready copy.- 5.3.1. Copy for journals or proceedings of meetings.- 5.3.2. Copy for reports.- 5.4. Original artwork versus copies.- 5.4.1. Reasons for copying artwork.- 5.4.2. Copying methods.- 5.5. Overlays and cover sheets.- 5.6. Marks of identification.- 5.7. Sending artwork to the publisher or printer.- 6. Slides.- 6.1. Introduction.- 6.2. Planning a slide presentation.- 6.2.1. The use of ‘introduction’ and ‘conclusion’ slides.- 6.2.2. The body of the presentation.- 6.2.3. Constructing a story-board.- 6.2.4. Rehearsal.- 6.3. The content of slides.- 6.3.1. Word slides.- 6.3.2. Data slides.- 6.3.3. Headings for data slides.- 6.4. Graphic standards for slides.- 6.4.1. Originals.- 6.4.2. Slide formats.- 6.4.3. Size of drafts and artwork.- 6.4.4. Line thickness.- 6.4.5. Character height.- 6.4.6. Character style.- 6.4.7. Character spacing.- 6.4.8. Layout for word slides.- 6.4.9. Tones and shading.- 6.4.10. Positive versus negative images.- 6.4.11. Contrast.- 6.5. The use of colour.- 6.5.1. Black-and-white versus coloured artwork.- 6.5.2. The use of coloured images.- 6.5.3. The use of coloured backgrounds with black lettering.- 6.6. Testing slides.- 6.7. Projection of slides.- 6.8. The design of lecture theatres.- 7. Posters.- 7.1. Introduction.- 7.2. The content of posters.- 7.2.1. General principles.- 7.2.2. The structure of the poster.- 7.2.3. Headings.- 7.3. Useful equipment for poster production.- 7.4. Graphic standards for posters.- 7.4.1. Poster formats.- 7.4.2. Size of drafts and artwork.- 7.4.3. Character height.- 7.4.4. Character style.- 7.4.5. Layout for text.- 7.4.6. Illustrations.- 7.4.7. Poster layout.- 7.4.8. The use of colour.- 7.5. Packing and transporting poster displays.- 8. Overhead projection transparencies.- 8.1. Introduction.- 8.2. Graphic standards for transparencies.- 8.2.1. Originals.- 8.2.2. Format and size.- 8.2.3. Line thickness.- 8.2.4. Character height.- 8.2.5. Layout.- 8.2.6. The use of colour.- 8.3. Techniques in the use of OHP transparencies.- 8.3.1. Overlays.- 8.3.2. Reveals.- 8.3.3. Masking.- 8.4. Testing OHP transparencies.- 9. Tape-slide programmes.- 9.1. Introduction.- 9.2. Planning a tape-slide programme.- 9.3. Writing the script.- 9.4. Graphic standards.- 9.5. The recording.- 10. Television.- 10.1 Introduction.- 10.2. Graphic standards for television.- 10.2.1. Format.- 10.2.2. Size of drafts and artwork.- 10.2.3. Line thickness.- 10.2.4. Character height.- 10.2.5. Tones and shading.- 10.2.6. Contrast.- 10.2.7. The use of colour.- 11. Materials, equipment and working comfort.- 11.1. Introduction.- 11.2. Basic essentials for black-and-white artwork.- 11.2.1. Paper.- 11.2.2. Pencils.- 11.2.3. Inks.- 11.2.4. Pens.- 11.2.5. Rulers and set squares.- 11.2.6. Templates and stencils.- 11.2.7. Erasers.- 11.2.8. Scalpels.- 11.2.9. Burnishers.- 11.2.10. Adhesives.- 11.2.11. Drafting tape.- 11.2.12. Drawing boards.- 11.3. Other useful items for black-and-white artwork.- 11.3.1. Self-adhesive tapes.- 11.3.2. Dry-transfer symbols and lettering.- 11.3.3. Tone sheets.- 11.3.4. ‘Pounce’ powder.- 11.3.5. Fixatives and varnishes.- 11.4. Additional materials for colour and OHP work.- 11.4.1. Self-adhesive colour sheets.- 11.4.2. Paints.- 11.4.3. Brushes.- 11.4.4. Cells and foils (acetate sheets).- 11.5. Working comfort.- 11.5.1. Organisation.- 11.5.2. Furniture.- 11.5.3. Lighting.- 12. Basic techniques.- 12.1. Care and preparation of paper.- 12.2. Ink work.- 12.2.1. Use of technical drawing pens.- 12.2.2. Blotting.- 12.2.3. Drawing ink lines.- 12.2.4. Finishing-off ink lines.- 12.2.5. Use of templates and stencils.- 12.2.6. Short cuts.- 12.3. Correcting errors in ink work.- 12.3.1. General comments.- 12.3.2. Cut-and-stick corrections.- 12.3.3. Edge-crossing.- 12.3.4. Correcting with a knife.- 12.3.5. Correcting with paint.- 12.4. Use of dry-transfer materials.- 12.4.1. Lettering.- 12.4.2. Tones.- 12.4.3. Making corrections.- 12.5. Use of self-adhesive tones and colours.- 12.5.1. Methods of application.- 12.5.2. Trapped air bubbles.- 12.5.3. ‘Windows’.- 12.6. Simple object drawing for line diagrams.- 12.6.1. General principles.- 12.6.2. Basic shapes.- 12.6.3. Lighting.- 12.6.4. Special effects.- 12.6.5. Making symmetrical shapes.- 12.6.6. Observation of objects.- 13. Working method.- 13.1. Planning the illustration.- 13.1.1. Choice of media.- 13.1.2. Summary of standards.- 13.2. Making the draft.- 13.2.1. Rough sketches.- 13.2.2. The use of graph paper for drafts.- 13.2.3. The use of typewriter grids.- 13.3. Using the draft.- 13.3.1. Fixing the draft to the artwork or drawing board.- 13.3.2. Transferring information from the draft to the final artwork.- 13.4. Making the final artwork.- 13.5. Making additions to the artwork.- Literature.
£40.49
Springer Ecology of Tidal Freshwater Forested Wetlands of the Southeastern United States
a huge range and FREE tracked UK delivery on ALL orders.
£248.47
Springer PCR for Clinical Microbiology: An Australian and International Perspective
a huge range and FREE tracked UK delivery on ALL orders.
£161.99
Springer Interrelations between Essential Metal Ions and Human Diseases
a huge range and FREE tracked UK delivery on ALL orders.
£170.99
Central European University Press The Triumph of Uncertainty: Science and Self in
Book SynopsisTauber, a leading figure in history and philosophy of science, offers a unique autobiographical overview of how science as a discipline of thought has been characterized by philosophers and historians over the past century. He frames his account through science’s – and his own personal – quest for explanatory certainty. During the 20th century, that goal was displaced by the probabilistic epistemologies required to characterize complex systems, whether in physics, biology, economics, or the social sciences. This “triumph of uncertainty” is the inevitable outcome of irreducible chance and indeterminate causality. And beyond these epistemological limits, the interpretative faculties of the individual scientist (what Michael Polanyi called the “personal” and the “tacit”) invariably affects how data are understood. Whereas positivism had claimed radical objectivity, post-positivists have identified how a web of non-epistemic values and social forces profoundly influence the production of knowledge. Tauber presents a case study of these claims by showing how immunology has incorporated extra-curricular social elements in its theoretical development and how these in turn have influenced interpretive problems swirling around biological identity, individuality, and cognition. The correspondence between contemporary immunology and cultural notions of selfhood are strong and striking. Just as uncertainty haunts science, so too does it hover over current constructions of personal identity, self knowledge, and moral agency. Across the chasm of uncertainty, science and selfhood speak.Table of ContentsForeword by Scott F. Gilbert Preface Introduction Chapter 1—Beginnings Chapter 2—On Ways of Knowing Chapter 3—Transitions Chapter 4—Rewriting Immunology Chapter 5—The Immune Self Chapter 6—Systems Philosophically Considered Chapter 7—Pursuing the Enigmatic Self Chapter 8—Rethinking Science Chapter 9—Outline of a Post-Positivist Philosophy of Science Chapter 10—A New Agenda Chapter 11—Personalizing Science Chapter 12—Moral Epistemology Chapter 13—Requiem for the Ego Chapter 14—Identity Reconsidered Conclusion Appendix 1—The Modernist Self Acknowledgements Bibliography Index
£57.75
Springer Verlag, Singapore The Structure of Healthy Life Determinants: Lessons from the Japanese Aging Cohort Studies
Book SynopsisThis book is the first one to examine the cause and effect of elderly people’s healthy life expectancy, providing models that are easy to understand. The novel point is the success achieved in constructing a single structural model of cause and effect of healthy life expectancy. In the final models of the authors’ studies, it was possible to clearly point out that it is not the case that lifestyle habits including an ideal diet directly provide for healthy life expectancy.This book is made up of published studies based on scientific evidence, using a vast amount of data based on about 8,000 in-home elderly people tracked longitudinally from 3 to 6 years, three times in all including baseline research, in a specific region of Japan. Therefore, health policy makers will be able to use this book as scientific evidence for creating area programs to promote good health that are focused on healthy longevity as the central issue. Academic researchers whose special fields are mainly public health will be able to learn both theory and practice to structurally analyze cause and effect of health factors.Table of Contents1. Introduction.- 2. Population aging trend of the world.- 3. SES, physical health, and long-term care needs.- 4. SES, comorbidity, activity limitations, and healthy life expectancy.- 5. SES, mental health, and need for long-term care.- 6. SES, social interaction, and health status.- 7. SES, dietary and lifestyle habits, and three health-related dimensions.- 8. SES, dietary and lifestyle habits, three health-related dimensions, and healthy survival days.- 9. SES, dietary quality, emotional well-being, and a five-year subjective health in middle-age.- 10. Causal relationships among three health-related dimensions.- 11. SES, environmental condition, three health-related dimensions, and healthy life expectancy.- Afterword.- Index.
£62.99
Springer Verlag, Singapore Ion Channels in Biophysics and Physiology
Book SynopsisThis book gathers relatively recent and significant topics in the field of ion channel research. Ion channels form the molecular basis for membrane excitability in cells present in the cardiovascular and nervous systems. In many non-excitable cells, ion channels contribute to diverse physiological functions, including the secretion of signaling compounds like hormones and insulin, cell volume regulation, intracellular signaling, especially Ca2+ signaling, etc. Many human diseases have been attributed to abnormal channel functions and defective membrane expression of channel proteins. On the other hand, ion channels are excellent models for studying protein biophysics, especially the allosteric regulation of protein function by miscellaneous stimuli. Therefore, research on ion channels carries significant meaning for the understanding of basic protein biophysics and diverse physiological functions. Such vital information also assists in developing novel and effective treatments for related human diseases. This book provides graduates and scientists in both basic and clinical levels a comprehensive understanding of cutting-edge advances and a useful and stimulating platform for tackling their own questions about ion channels.Table of ContentsAdvancing ion channel research with automated patch clamp (APC) electrophysiology platforms.- Methods & Challenges to Study Mechanosensitive Ion Channels.- The Polysite Pharmacology of TREK K2P channels.- Physiological functions, biophysical properties and regulation of KCNQ1 (KV7.1) potassium channels.- Context matters – Calcium channel splice variants and their effects in brain and cardiovascular function.- Structure-function of TMEM16 ion channels and lipid scramblases.- Distribution and Assembly of TRP Ion Channels.- Regulation of Ion Channel Function by Gas Molecules.- DEG/ENaC ion channels in the function of the nervous system: from worm to man.- Glial chloride channels in the function of the nervous system across species.- Physiological and pathological relevance of selective and non-selective Ca2+ channels in skeletal and cardiac muscle.- Lysosomal TRPML1 Channel: Implications in Cardiovascular and Kidney Diseases.- Store-Operated Calcium Entry in the Cardiovascular System.- The role of thermosensitive ion channels in mammalian thermoregulation.- Mechanotransduction ion channels in hearing and touch.- The functional properties, physiological roles, channelopathy and pharmacological characteristics of the Slack (KCNT1) channel.- Ion Channels in Anesthesiology.
£151.99
World Scientific Publishing Co Pte Ltd Nobel Prizes And Nature's Surprises
Book SynopsisEach year the Nobel Prizes in the natural sciences reveal amazing discoveries. New milestones in the relentless advance of science are identified. The growth of knowledge and its evolution can be researched in the Nobel archives where nominations are kept secret for 50 years after the awards have been made. They represent a treasure for real-time assessment of science. Norrby's earlier book, Nobel Prizes and Life Sciences (2010) examined the unique archival records until 1959.The present book takes us up to 1962, surveying a range of dazzling discoveries. All prizes in immunology are reviewed. Their impact on our capacity to control infectious diseases and transplant organs are highlighted. The Nobel year 1962 is exceptional in recognizing the most major advance in biology since Darwin in 1859 presented his theory of evolution. This was the dramatic discovery of the double-helix structure of DNA by Watson and Crick in 1953. The era of molecular biology had begun. Its explosive development continues into the present.Table of ContentsA Magician of Virology from Australia; A Divided Nobel Prize and a New Era in Immunology; More Nobel Prizes in Immunology; Immunity, Infections and Transplantations; Transgressing Borders in Science and Scenes of Life; Making Sense of Hearing: Art and Science; Unraveling the Complexity of Protein Folding; "It's So Beautiful, You See, So Beautiful"; Coda.
£45.60
Elsevier Science & Technology Atlas of Hybrid Imaging Sectional Anatomy for
Book SynopsisTable of Contents1. BRAIN 2. NECK and MAXILLOFACIAL REGION
£114.30
McGill-Queen's University Press The Codex Canadensis and the Writings of Louis Nicolas
a huge range and FREE tracked UK delivery on ALL orders.
£75.05
Oxford University Press Beyond Interdisciplinarity Boundary Work Communication and Collaboration
a huge range and FREE tracked UK delivery on ALL orders.
£999.99
Cambridge University Press What Teeth Reveal about Human Evolution
Book SynopsisThis book shows what fossil hominin teeth can tell us about human evolution, integrating the latest research insights with current debates and issues in palaeoanthropology. Written in an accessible style, it will appeal to students and researchers in the fields of biological anthropology, evolutionary biology, palaeontology, dental science and oral biology.Trade Review'This is an extensively researched and well-written - not to mention much-needed - book on the unsung heroes of human paleontology: teeth. … The author obviously has done her homework and the references in the book are as up to date as they can be in a constantly changing field. I even found some references that I had not yet read and so I learned something, too. This is an informative read for anyone interested in teeth and/or human evolution. The fact that it is clearly written will make it accessible to general readers. But it also provides enough detail, not to mention an extensive literature review, to make it useful for students entering the field of paleoanthropology.' Shara E. Bailey, The Quarterly Review of Biology'The book is designed for undergraduates and non-professionals, but I think that it provides sufficient detail across the breadth of hominin dental studies that it would also offer a good reference piece for professionals and academics that focus on related research topics. …This book would work well in undergraduate courses on human evolution and as a supplementary companion to graduate seminars in related topics.' James T. Watson, Dental Anthropology'… This highly accessible book has drawn from a wide range of recent findings and publications and presents it in a manner which would definitely appeal to a mixed audience. Reading through, there is a strong sense of narrative, which takes the reader on a seemingly informal tour through hominin dentary science. With this open style and coverage of current literature, this book has appeal to readers from a broad range of specialisms …' Ben GarrodTable of ContentsIntroduction; Part I. Teeth and Australopiths: 1. March of the bipeds: the early years; 2. Dentally derived dietary inferences: the australopiths; 3. Curious canines; 4. Incisive insights into childhood; Part II. Teeth and the Genus Homo: 5. March of the bipeds: the later years; 6. Dentally derived dietary inferences: the genus Homo and its diminishing dentition; 7. Long in the tooth: life history changes in Homo; 8. Knowing Neanderthals through their teeth; 9. Insights into the origins of modern humans and their dental diseases; 10. Every tooth a diamond.
£45.59
Nova Science Publishers Inc Cholinesterase: Production, Uses and Health
Book SynopsisCholinesterase is a family of enzymes that catalyze the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid, a reaction necessary to allow a cholinergic neuron to return to its resting state after activation. Cholinesterases are the target enzyme of numerous pesticides and chemical warfare agents and have been used for over two decades in the detection of these compounds. In this book, the authors present current research in the production, uses and health effects of cholinesterase. Topics discussed include cholinergic therapy for autistic spectrum disorders; acetylcholinesterase inhibitors in the treatment of Alzheimer''s disease; use of fish brain and muscle acetylcholinesterase as a biomarker to monitor water pollution and the evolutionary aspects of molecular forms and biological functions of acetylcholinesterase.
£106.49
HarperCollins Publishers Inc The Return of the God Hypothesis
Book SynopsisThe New York Times bestselling author of Darwin’s Doubt, Stephen Meyer, presents groundbreaking scientific evidence of the existence of God, based on breakthroughs in physics, cosmology, and biology.Beginning in the late 19th century, many intellectuals began to insist that scientific knowledge conflicts with traditional theistic belief—that science and belief in God are “at war.” Philosopher of science Stephen Meyer challenges this view by examining three scientific discoveries with decidedly theistic implications. Building on the case for the intelligent design of life that he developed in Signature in the Cell and Darwin’s Doubt, Meyer demonstrates how discoveries in cosmology and physics coupled with those in biology help to establish the identity of the designing intelligence behind life and the universe. Meyer argues that theism—with its affirmati
£25.49
The University of Chicago Press Georg Forster
Book SynopsisTrade Review2016--Winner of the Leipzig Book Fair Prize (Non-fiction) 2015--Winner of the Gleim Literature Prize "A rich and exciting book. . . . It imagines Forster as a thinker and therefore the relationship of the two main parts of his biography--circumnavigation and revolution--unite for the first time."--Gustav Seibt "S ddeutsche Zeitung " "The two key concepts of the era, 'nature' and 'revolution, ' which were in Forster's thinking and actions, Goldstein reconstructs in an impressive way: in a thrilling, lucid style drawing on Forster's diaries, letters, and works."--Oliver Pfohlmann "Neue Z rcher Zeitung " "The revolution is not a figment, but a natural phenomenon, a 'self-ignition of the reason' for Forster. To have developed this relationship, a 'natural revolution, ' from Forster's natural and human science is Goldstein's no small merit."--Alexander Kosenina "Frankfurter Allgemeine Zeitung " "Goldstein explores Forster's experience of life and the ambivalent relationship between nature and philosophy. He shows Forster as more than a shipwrecked hero, but rather as an insightful thinker who was as bold as he was stoic."--Benedikt Erenz "ZEIT " "Using extensive quotes, Goldstein thrillingly depicts Forster's great journey, the impressions and ordeals of which are said to have remained with him for life."--Janika Gelinek "Neue Z rcher Zeitung " "An extraordinary life story that is thrilling to read."--Lina Kokaly "Radio Bremen "
£999.99
