Genetics (non-medical) Books
Springer Verlag, Singapore DNA of Sustainability
£143.99
Springer Verlag, Singapore Targeting Epigenetics in Inflammatory Lung
Book SynopsisThis book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.Table of ContentsChapter 1. Introduction to Lung Diseases.- Chapter 2. Introduction to Epigenetics.- Chapter 3._Epigenetic mechanisms in Inflammation.- Chapter 4. Epigenetic regulator of inflammatory gene expression.- Chapter 5. Epigenetics of Asthma.- Chapter 6_. Epigenetic optimization in chronic obstructive pulmonary disease (COPD.- Chapter 7. Epigenetics of Lung Cancer.- Chapter 8. Epigenetics of Pulmonary Tuberculosis.- Chapter 9. Epigenetics of Idiopathic Pulmonary Fibrosis.- Chapter 10. Epigenetics of influenza-A virus infection.- Chapter 11. Epigenetics of rhinovirus.- Chapter 12. Epigenetics of SARS-Cov2 (Covid-19).- Chapter 13. Epigenetics of Haemophilus Influenzae.- Chapter 14. Future Prospects and Challenges.- Chapter 15. Targeting epigenetics in pulmonary arterial hypertension.
£125.99
Obelisco Arbol Genealogico, El
Book Synopsis
£22.31
Antoni Bosch Editor, S.A. Quiénes somos y cómo llegamos hasta aquí: ADN
Book SynopsisLa extracción de ADN de los huesos de nuestros ancestros ha permitido resolver importantes controversias sobre la prehistoria, hasta el punto de cambiar su interpretación. Hoy en día puede extraerse y analizarse ADN antiguo y, en buena medida gracias a las aportaciones del propio David Reich, se ha puesto de manifiesto que la genómica es tan relevante como la arqueología o la lingüística a la hora de estudiar las poblaciones del pasado. En Quiénes somos y cómo hemos llegado hasta aquí, Reich nos enseña que el genoma humano, además de aportar toda la información que necesita un óvulo humano fertilizado para desarrollarse, contiene en sí mismo la historia de nuestra especie. La revolución de la genómica y del ADN antiguo está transformando lo que sabemos sobre el linaje de los humanos y, según nos explica Reich, los estudios de ADN revelan una larga historia de desigualdad entre poblaciones distintas, así como entre ambos sexos y entre individuos de una misma población. Esta obra desmiente la interpretación ortodoxa de que no hay diferencias biológicas relevantes entre poblaciones humanas y, al mismo tiempo, utiliza los sólidos datos de la genómica para ilustrar la improbabilidad de que las diferencias, que sí existen, se correspondan con los estereotipos de siempre.
£22.67
Elsevier Science Craniofacial Development
Trade ReviewPraise for the Series: "Outstanding both in variety and in the quality of its contributions." --NatureTable of ContentsPart-1 Craniofacial Morphogenesis and Regeneration: From Cells to Tissues to Organs 1. Craniofacial Muscle Development Inbal Michailovici, Tamar Eigler and Eldad Tzahor 2. Mandible and Tongue Development Carolina Parada 3. Cellular and Molecular Mechanisms of Palatogenesis Yu Lan, Jingyue Xu and Rulang Jiang 4. Genetic Influences on Temporomandibular Joint Development and Growth Robert J Hinton, J Jing and JQ Feng 5. Regulatory Mechanisms Driving Salivary Gland Organogenesis Belinda R. Hauser and Matthew P. Hoffman 6. The Development of the Calvarial Bones and Sutures and the Pathophysiology of Craniosynostosis Mamoru Ishii, Jingjing Sun, Man-Chun Ting and Robert E. Maxson 7. Tissue Interactions Regulating Tooth Morphogenesis and Renewal Anamaria Balic and Irma Thesleff 8. Stem Cells in to Toth Development, Repair and Regeneration Tian Yu, Ana Angelova Volponi, Rebecca Babb, Zhengwen An and Paul T Sharpe 9. Development and integration of the Ear Jennifer C. Fuchs and Abigail S. Tucker Part- 2 Craniofacial Patterning and Signaling Mechanisms 10. Zebrafish Craniofacial Development: A Window Into Early Patterning Lindsey Mork and Gage Crump 11. Regulation of Jaw Length During Development, Disease, and Evolution Richard A. Schneider 12. Facial Morphogenesis: Physical and Molecular Interactions Between the Brain and Face Ralph Marcucio, Benedikt Hallgrimsson and Nathan M. Young 13. Developmental Plasticity of Patterned and Regenerating Oral Organs J. Todd Streelman, Ryan F. Bloomquist and Teresa E. Fowler 14. Regulating Craniofacial Development at the 3’ End: MicroRNAs and their Function in Facial Morphogenesis Andre L.P. Tavares, Kristin B. Artinger and David E. Clouthier 15. Transcription Factors in Craniofacial Development: From Receptor Signaling to Transcriptional and Epigenetic Regulation Yongchao Gou, Tingwei Zhang and Jian Xu Part- 3 Disease Models, Human Genetics, Genomics and Dynamic Imaging 16. Mouse Models of Rare Craniofacial Disorders Annita Achilleos and Paul A. Trainor 17. From Bench to Bedside and Back: Improving Diagnosis and Treatment of Craniofacial Malformations Utilizing Animal Models Alice F. Goodwin, Rebecca Kim, Jeffrey O. Bush and Ophir D. Klein 18. Signaling Pathways in Craniofacial Development: Insights from Rare Skeletal Disorders Cynthia L. Neben and Amy E. Merrill 19. Clinical and Genomic Approaches for the Diagnosis of Craniofacial Disorders Pedro A.Sanchez-Lara 20. Morphometrics, 3D Imaging, and Craniofacial Development Benedikt Hallgrimsson, Christopher J. Percival, Rebecca Green ,Nathan M. Young, Washington Mio and Ralph Marcucio 21. Imaging the Cell and Molecular Dynamics of Craniofacial Development Le A. Trinh and Scott E. Fraser
£156.75
Oxford University Press Ancestors in Our Genome
Book SynopsisThe complete DNA molecules comprising the human genome were deciphered two decades ago. With this discovery began a remarkable genomic voyage back in time yielding a new science of human evolution. We are just beginning to unravel our full genomic history and answering age-old questions about how and when we evolved. For the first time, we are finding our ancestors in our genome and gleaning tantalizing clues about our past. Molecular anthropologist Eugene E. Harris now gives us an updated and expanded version of the original Ancestors in Our Genome. Written from the perspective of population genetics, and in simple terms, his book traces human origins back to our earliest human ancestors and explains how our genome has adapted as we spread to colonize new regions on Earth. Harris''s book reveals the latest insights into our relationships with our extinct cousins, the Neandertals and Denisovans, and describes where, when and to what extent we mated with them, probing the good and bad cTrade ReviewShortlisted for the 2015 Phi Beta Kappa Award in Science.[Harris] has written an excellent analysis of modern human evolution from a molecular evolution perspective. [...] This is the best book I've ever read on the subject of random genetic drift. * Larry Moran, Professor Emeritus, Department of Biochemistry at the University of Toronto *Simply indispensable for any reader wishing to learn about the latest research on human origins." -Library Journal, starred reviewThe book is technical, thus challenging for the general reader, but is written well enough to make the effort worthwhile. * Publisher's Weekly *Ancestors in Our Genome tells the amazing story of human evolution as it has been revealed by the study of our DNA. Eugene Harris, a rare anthropologist who has studied the differences in the DNA of humans and other primates, has written a superb book about the latest discoveries comparing the DNA genomes of apes and humans-both living and fossilized . . . An enjoyable and wonderfully enlightening read. * Jody Hey, Professor and Director, Center for Computational Genomics and Genetics, Temple University and author of Genes, Categories, and Species *In a lucid and engaging style, Eugene Harris delivers a clear account of the latest insights in genomic studies that are giving humans a more comprehensive understanding of our evolutionary history, our place in nature, and where we may be headed. * Donald Johanson, Virginia M. Ullman Chair in Human Origins and Founding Director of the Institute of Human Origins, Arizona State University *It is a daunting and confusing task to make sense of the avalanche of genetic information that has recently become available. Fortunately, Harris's book is a concise and engaging explanation of what we have learned about human evolution from studying genomes. Harris clearly explains without jargon the basics of genetics and genomics, how and when humans evolved, and what about our genes make us different from our closest living and extinct relatives. * Daniel Lieberman, Chair, Department of Human Evolutionary Biology, Harvard University and author of The Story of the Human Body: Evolution, Health, and Disease *In the 'Age of Genomics,' this book is an absolute must-have for anyone interested in human evolution. In the most accessible manner, Eugene E. Harris enlightens how and why genomes represent such powerful evidence to understand our past. If you want to know why paleontologists and geneticists fight over evolutionary trees, whether chimpanzees and primitive hominins interbred after they split, how large the first human population was, or how in modern humans bad genes could become good genes, open Ancestors in Our Genome. * Jean-Jacques Hublin, Director, Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology *Written in a very clear and easy to follow style, Ancestors in Our Genome is notable for its inclusion of really up-to-date research. For the uninitiated, it's a great guide to the whole subject area. If you already have some knowledge, it delivers important insights on the latest findings. * Evan Hadingham, Senior Science Editor at NOVA WGBH *Eugene Harris' Ancestors in Our Genome is an extremely clear and readable introduction to the studies of genetics and genomics that are advancing our understanding of our evolutionary history. He describes, in clear prose, both the most recent discoveries in primate phylogeny and human evolution and the methods underlying them. Most significantly, he emphasizes how studies of population genetics and genomic sequencing interact in interpretations of primate and human genetic evolution. * John G. Fleagle, Evolutionary Anthropology *Ancestors in Our Genome provides a good basic view of modern human evolutionary biology. Recommended. * Choice *One of the book's laudable features is its accuracy. Errors are common in popular science books, but not this one. Harris cites some of the most pertinent research on the molecular foundations of human evolution, and he is invariably true to the original research. ... Though the effort to read this book may be considerable for those not familiar with genomic science, it is well worth it. Readers will come away from it with a powerful and up-to-date understanding of human evolution and of evolution in general. * Reports of the National Center for Science Education *...readers looking for an up-to-date, clearly written, and well-illustrated tour through the dynamics of human evolution will find no better guide than this compelling volume. * Bioscience *...a good overview of the state of the science regarding the genomics of human evolution. * The Scientist *All in all, the book shines when it discuses the recent technological advances in DNA sequencing, which allows readers a never-before-seen view into our genetic history. ...if you are interested in learning about the most recent findings in population genetics and human origins, then this book is a great start. * The Daily of the University of Washington *Harris gives us glimpses of the science behind these amazing discoveries of our ancestors. He explains the basics for non-biologists before diving deep into human genomics and population genetics. He unobtrusively notes his involvement in the work. The writing is always clean and light in spite of the tough concepts and jargon. The result is an incredible story of what genes and genomes can tell us about our distant past and our current condition. * The Key Reporter *[A]ccessible, informative, and entertaining. ... Ancestors in Our Genome is impressively thorough and current and will be a great resource to anyone interested in understanding how population genomic theory has been used to test fundamental hypotheses concerning the origins of our species. * American Journal of Human Biology *[O]n the whole this is a substantive, engaging, and worthwhile introduction to molecular anthropology for educated nonexperts. * Quarterly Review of Biology *
£15.99
Oxford University Press A Passion for DNA
Book SynopsisIn 1953, two young, unknown scientists sparked a worldwide revolution. Studying DNA for clues to the nature of genes, James Watson and Francis Crick deduced its molecular composition - two chains twisted into a double helix - and immediately realized that the structure implied how genes were copied and passed from one generation to the next.Their observation has had extraordinary consequences: the discovery of a genetic code that all living things share and the realization that the code translates into proteins; the ability to alter an organism''s genetic make-up; recognition that diseases like cancer begin when genes go wrong; the foundations of a biotechnology industry and the means of cloning plants and animals; a start on cataloguing human genes; and the glimmer of a new kind of medicine that uses DNA therapeutically.In the midst of the ferment, its instigator Jim Watson has been tireless. A principal architect and visionary of the new biology, a Nobel Prize-winner at 34 and best-sTrade ReviewReview from previous edition James D. Watson . . . has always been a man of passion and strong views . . . His writings on the important issues of the day, prepared over a period of more than thirty years and presented in the 25 essays of this wonderful book, are only slightly less provocative than his frequently startling spontaneous remarks. * Bruce Alberts, President, National Academy of Sciences *Table of ContentsAUTOBIOGRAPHICAL FLIGHTS; VALUES FROM A CHICAGO UPBRINGING; GROWING UP IN THE PHAGE GROUP; MINDS THAT LIVE FOR SCIENCE; EARLY SPECULATIONS AND FACTS ABOUT RNA TEMPLATES; BRAGG'S FOREWORD TO THE DOUBLE HELIX; BIOGRAPHIES: LURIA, HERSHEY, AND PAULING ; RECOMINANT DNA CONTROVERSIES; IN FURTHER DEFENSE OF DNA; STANDING UP FOR RECOMBINANT DNA; THE NOBELIST VERSUS THE FILM STAR; THE DNA BIOCHEMICAL CANARD ; ETHOS OF SCIENCE; MOVING TOWARDS THE CLONAL MAN: IS THIS WHAT WE WANT?; THE DISSEMINATION OF UNPUBLISHED INFORMATION; SCIENCE AND THE AMERICAN SCENE; THE NECESSITY FOR SOME ACADEMIC ALOOFNESS; STRIVING FOR EXCELLENCE; SUCCEEDING IN SCIENCE: SOME RULES OF THUMB ; WAR ON CANCER; THE ACADEMIC COMMUNITY AND CANCER RESEARCH; MAINTAINING HIGH QUALITY CANCER RESEARCH IN A ZERO-SUM ERA; THE SCIENCE FOR BEATING DOWN CANCER ; SOCIETAL IMPLICATIONS OF THE HUMAN GENOME PROJECT; MOVING ON TO HUMAN DNA; ETHICAL IMPLICATIONS OF THE HUMAN GENOME PROJECT; GENES AND POLITICS; FIVE DAYS IN BERLIN; GOOD GENE, BAD GENE: WHAT IS THE RIGHT WAY TO FIGHT THE TRAGEDY OF GENETIC DISEASE?; VIEWPOINT: ALL FOR THE GOOD - WHY GENETIC ENGINEERING MUST SOLDIER ON ; AFTERWORD: ENVOI - DNA, PEACE AND LAUGHTER ; NAME INDEX, SUBJECT INDEX
£16.26
Oxford University Press ENVIRONMENTAL DNA C For Biodiversity Research and
Book SynopsisEnvironmental DNA (eDNA) refers to DNA that can be extracted from environmental samples (such as soil, water, feces, or air) without the prior isolation of any target organism. The analysis of environmental DNA has the potential of providing high-throughput information on taxa and functional genes in a given environment, and is easily amenable to the study of both aquatic and terrestrial ecosystems. It can provide an understanding of past or present biological communities as well as their trophic relationships, and can thus offer useful insights into ecosystem functioning. There is now a rapidly-growing interest amongst biologists in applying analysis of environmental DNA to their own research. However, good practices and protocols dealing with environmental DNA are currently widely dispersed across numerous papers, with many of them presenting only preliminary results and using a diversity of methods. In this context, the principal objective of this practical handbook is to provide biTrade ReviewThis volume fills a much-needed gap, offering a gentle introduction into the field of environmental DNA, which will be especially useful for readers of minor to intermediate experience with environmental DNA. * Vasco Elbrecht, Centre for Biodiversity Genomics, University of Guelph, The Quarterly Review of Biology *An excellent instructional book or supplementary reading for any eDNA based classes...It is a timely and important addition to the field of molecular ecology, and will undoubtedly remain the go-to book on metabarcoding for several years. * Dr Anthony A. Charlton, Macquarie University, Sydney, Australia, Molecular Ecology *This book is a timely overview of eDNA as a complimentary and non-invasive approach for investigating and monitoring biodiversity. The book is an ideal introduction to all ecologists looking to eDNA, but also speaks to the more experienced researchers in molecular ecology. Lastly, it provides textbook material for university courses around the world. * Philip Francis Thomsen, Trends in Ecology & Evolution Journal *If you are contemplating moving into this topic, or just want to understand it better, do try and get your hands on a copy - something that might not be that easy just now as I understand the book has proved to be so popular that it is already having to be reprinted. * IMA FUNGUS *In a world faced with accelerating environmental change and loss of biodiversity, this book is a timely overview of eDNA as a complementary and noninvasive approach for investigating and monitoring biodiversity ... an ideal introduction to all ecologists looking to eDNA as a method of choice, but also speaks to the more experienced researchers in molecular ecology. Lastly, it provides textbook material for university courses around the world, where eDNA is continuously increasing in popularity. * Philip Francis Thomsen, Department of Bioscience, University of Aarhus, Trends in Ecology and Evolution *Table of Contents1: Introduction to environmental DNA (eDNA) 2: DNA metabarcode choice and design 3: Reference databases 4: Sampling 5: DNA extraction 6: DNA amplification and multiplexing 7: DNA sequencing 8: DNA metabarcoding data analysis 9: Single-species detection 10: Environmental DNA for functional diversity 11: Some early landmark studies 12: Freshwater ecosystems 13: Marine environments 14: Terrestrial ecosystems 15: Palaeoenvironments 16: Host-associated microbiota 17: Diet analysis 18: Analysis of bulk samples 19: The future of eDNA metabarcoding
£107.50
Taylor & Francis Forensic DNA Profiling
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Taylor & Francis Ltd The Human Genome in Health and Disease
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£128.25
Taylor & Francis Ltd Evolutionary Psychology
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£123.50
Taylor & Francis Ltd Evolutionary Psychology
Book SynopsisEvolutionary Psychology: The Basics is a jargon-free and accessible introduction to evolutionary psychology, which examines behaviour, thoughts, and emotions in relation to evolutionary theory.Reader and Workman outline how evolutionary thinking can enhance the core areas of psychology: social, developmental, biological, cognitive, and individual differences/abnormal psychology. Covering topics such as genetics and natural selection, mate choice, culture, morality, mental health, and childhood, among others, the book integrates psychology into the biological sciences and explains the different approaches in the field by evaluating current and past evolutionary research and theory. Key studies and theories are explored in an accessible way, with the work of key evolutionary and behavioural scientists from Darwin to Dawkins examined and explained.Including a glossary and further reading, this is the essential introduction to evolutionary psychology for students Table of ContentsCHAPTER 1. INTRODUCTION TO NATURAL SELECTION AND GENETICSCHAPTER 2. SEXUAL SELECTION AND MATE CHOICECHAPTER 3. LIVING WITH OTHERS: EVOLUTION, SOCIAL BEHAVIOUR AND MORALITYCHAPTER 4. EVOLUTION AND DEVELOPMENTCHAPTER 5. THINKING AND FEELING: COGNITION AND EMOTIONSCHAPTER 6. WHY DO PEOPLE VARY? INDIVIDUAL DIFFERENCES AND MENTAL ILLNESSCHAPTER 7. EVOLUTION, CULTURE AND LANGUAGE
£20.19
Taylor & Francis Ltd Defrosting Ancient Microbes
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Taylor & Francis Downs Syndrome Screening and Reproductive Politics
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Taylor & Francis The Future of Man The BBC Reith Lectures 1959 7 Routledge Library Editions Evolution
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Taylor & Francis The Future of Man The BBC Reith Lectures 1959 Routledge Library Editions Evolution
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Taylor & Francis Ltd Law Practice and Politics of Forensic DNA Profiling
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Taylor & Francis The Masterpiece of Nature
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Taylor & Francis The Masterpiece of Nature
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Taylor & Francis Ethical Social and Psychological Impacts of Genomic Risk Communication Earthscan Risk in Society
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Taylor & Francis Ltd Phenomics
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Taylor & Francis Ltd Comparative Genomics and Proteomics in Drug Discovery Vol 58
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Taylor & Francis Ltd Structural Genomics and High Throughput Structural Biology
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Taylor & Francis Ltd Introduction to Statistical Methods in Modern Genetics
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Taylor & Francis Ltd Epigenetics in Biology and Medicine
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Taylor & Francis Ltd Genome Editing in Plants
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Taylor & Francis The Handbook of Sex Differences Volume I Basic Biology
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Taylor & Francis Ltd Bioinformatics and Human Genomics Research
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Taylor & Francis Ltd Transcription Factors Human Molecular Genetics Series
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Taylor & Francis Ltd Nucleic Acid Testing for Human Disease
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Taylor & Francis Ltd Handbook of Detection of Enzymes on Electrophoretic Gels
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Taylor & Francis Ltd Next Generation Sequencing in Forensic Science
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Taylor & Francis Ltd Hox Modules in Evolution and Development
Book SynopsisFew, if any, genes have had the same level of impact on the field of evolutionary-developmental biology (evo-devo) as the Hox genes. These genes are renowned for their roles in patterning the body plans and development of the animal kingdom. This is complemented by the distinctive organisation of these genes in the genome, with them frequently being found as clusters in which gene position is linked to when and where the individual genes are expressed, particularly during embryogenesis. This book provides the latest overviews of Hox gene organisation and function for major clades of animals from across the animal kingdom. With the rapidly increasing availability of high-quality whole genome sequences from an ever-expanding range of species, it is becoming increasingly evident that there is great diversity in the organisation of Hox genes. These great strides in genome sequencing are wedded to important developments in our ability to detect expression and disrupt gene function in speTable of ContentsSeries Preface. Preface. About the Editor. Contributors. Introduction to Hox Modules in Evolution and Development. Multiple Layers of Complexity in the Regulation of the Bithorax Complex of Drosophila. The Role of Hox Genes in the Origins and Diversification of Beetle Horns. Duplication and Evolution of Hox Clusters in Chelicerata (Arthropoda). Structural Constraints in Hox Clusters: Lessons from Sharks and Rays. Evolution of Cyclostome Hox Clusters. Hox Genes in Echinoderms. Hox Genes in Mollusca. The Evolution of Hox Genes in Spiralia. Index.
£87.39
Taylor & Francis Ltd From Proteins to Proteomics
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Taylor & Francis Genetic Ancestry
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Taylor & Francis Ltd RNA the Epicenter of Genetic Information
Book SynopsisThe origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself. Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information.Key Features Documents the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers. The Open Access version of this book, available at www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.Trade Review“Thrilling and provocative ... There is a need for such a book... There’s nothing quite like this out there.An epic tale of biology’s central molecule, RNA.DNA does only one thing, store information. RNA has a thrilling plethora of functions, including telling DNA what to do. This book takes the reader on an odyssey through the wonders of RNA and its central role in biology.DNA science dominated the second half of the 20th Century, but it’s clear that the 21st Century belongs to RNA. This long-overdue book reveals the diverse wonders of RNA in a series of thrilling and provocative stories.”Tom Cech, Nobel laureate, University of Colorado Boulder_____________________________________“The book is truly monumental and will be treasured by RNA scientists and others, as well. It beautifully captures the excitement and wonder that I have been lucky to experience working in the RNA field since the early 1960s.”Joan Steitz, Yale University_____________________________________“This book is really disruptive and presents a coherent view of our understanding of biology in terms of the genetic molecules, the nucleic acids, DNA and RNA. It covers an immense territory of molecular biology and its history of discoveries, all presented with a clear-cut intellectual thread.... It is very timely by its breadth and emphasis on the role of RNA in biology. It makes a strong case for RNA and its late acceptance... the fight uphill, like that of Sisyphus, was tough and demanded a lot of perseverance. It is really rather complete.”Eric Westhof, University of Strasbourg_____________________________________“The book is unique. It provides the long-overdue correction of the still widespread static views on evolution, development and genome organization and function. It has the potential to induce radical changes in widely held views and attitudes.”Peter Vogt, Scripps Research Institute, La Jolla_____________________________________"History is the key to our modern understanding of RNA. This magnum opus describes how science, scientific thought and landmark discoveries revealed the central role of RNA in molecular biology and evolution. The authors are not only modern pioneers of RNA science, but also the best histo-RNA-ians of our time.”John Rinn, University of Colorado, Boulder_____________________________________"RNA, the Epicenter of Genetic Information is much more than what its title might suggest. This epic book by Mattick and Amaral superbly reflects the continuing excitement about RNA research. It is not only a description of our current understanding of the role of RNA in cell and developmental biology but is also a useful history of molecular biology. Each of the eighteen chapters is a brilliantly written semi-autonomous essay on a particular segment of the RNA odyssey. I wholeheartedly recommend this book to anybody interested in the biology of RNA, in evolution, and in the organization and function of complex genomes." Witold Filipowicz, Friedrich Miescher Institute for Biomedical Research, Basel_____________________________________"Those who might think that this book is only for the scientists, think again. It is not. It will appeal in equal measure to the thinking generalist and culturally curious interested in the thrilling history of molecular biology, the wonders of the long-overlooked central molecule RNA and its pivotal role in human development and evolution.An epic, provocative, and highly original book that highlights the way science is so often sidetracked by preconceptions and hubris, and explores the struggle to understand all that junk DNA we were told we had. The junk is not junk! The answers are all there. A story and a journey not to be missed!"Gabriel Farago (USA TODAY Bestselling author of the Jack Rogan Mysteries Series) Table of ContentsPreface, Chapter 1. Overview, Chapter 2. The genetic material?, Chapter 3. Halcyon days, Chapter 4. Worlds apart, Chapter 5. Strange genomes, strange genetics, Chapter 6. The Age of Aquarius, Chapter 7. All that junk, Chapter 8. The expanding repertoire of RNA, Chapter 9. Glimpses of a modern RNA world, Chapter 10. Genome sequences and transposable elements, Chapter 11. The human genome, Chapter 12. Small RNAs with mighty functions, Chapter 13. Large RNAs with many functions, Chapter 14. The epigenome, Chapter 15. The programming of development, Chapter 16. RNA and repeats rule, Chapter 17. Plasticity, Chapter 18. Beyond the jungle of dogmas, References
£41.99
Taylor & Francis Ltd The Genetics of Political Behavior How Evolutionary Psychology Explains Ideology
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Taylor & Francis Ltd Genomic Sequence Analysis for Exon Prediction Using Adaptive Signal Processing Algorithms
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Taylor & Francis Ltd Genomic Sequence Analysis for Exon Prediction Using Adaptive Signal Processing Algorithms
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Taylor & Francis Ltd Bioinformatics and RNA
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Taylor & Francis Routledge International Handbook of Social Neuroendocrinology
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Taylor & Francis Ltd Techniques in Genetic Engineering
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Taylor & Francis Ltd Genomes 5
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Taylor & Francis Routledge Handbook of Sport and Exercise Systems Genetics Routledge International Handbooks
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Taylor & Francis Ltd Genetics and the Psychology of Motor Performance
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Taylor & Francis Forensic DNA Transfer
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Taylor & Francis Ltd Vertebrate Cranial Placodes
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Taylor & Francis Ltd The Evolution of Human Cleverness
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