Gastroenterology Books

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Book SynopsisAround a quarter of the world's population is affected by iron deficiency, and women of childbearing age as well as children and adolescents are considered a particular risk group. This reference book deals with the latest scientific findings concerning the iron supply of the human organism with natural foods. It dispels the misconception that plant iron is less valuable than animal iron by presenting the absorption of iron from plant foods via a newly discovered metabolic pathway. From this, new points of view can be derived for vegetarians and vegans, who until now have belonged to the risk group. Furthermore, it is dedicated to forward-looking possibilities of diagnosing iron deficiency and describes modern concepts for determining the bioavailability of iron in food. New findings on the biochemistry of iron in brain metabolism, the description of the different reference values of the international professional societies and practical advice for special diets, risk groups and age groups as well as cooking recipes with simple information on iron intake complete the work. The book is aimed at nutritionists and medical practitioners, nutrition and food scientists, dieticians, pharmacists and sports scientists.Table of ContentsIntroduction.- Biochemistry of iron.- Systemic iron homeostasis.- Anemia and iron deficiency.- Diagnosis of iron deficiency states.- The iron requirement.- Bioavailability.- Diet in iron deficiency.- Iron and special diets.- Iron supplementation.

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Book SynopsisA no-nonsense, at times humorous, guide to gut health and disease, backed by the most recent science and drawing on lived examples from the author's professional practice and personal health history and including gut health basics, the building blocks of food, the gut microbiome and the seven commonest gut conditions, finishing with a roadmap to a blissful gut. With this book, you will get to appreciate the complex nature of the human gut but also learn to nourish your internal ecosystem and cope with the most common gut conditions: Reflux disease, Bloating, Constipation, Diarrhoea, Irritable Bowel Syndrome, Food Intolerance and Haemorrhoids. Sandra shares her 'four pillars' approach and addresses the fundamental relationship between gut health and mental health, finishing with recipes to help you translate the nutritional science into gut-loving meals.Table of ContentsBack to basics; Gut microbiome; Feeding your gut microbiome; The volcanic throat (Reflux); Bloating; Faecal challenge (Constipation); Bumfluenza (Diarrhoea); IBS; Food intolerance; Bum-dumplings (Haemorrhoids/piles); How to achieve a blissful gut, with 24 gut-loving recipes

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Book SynopsisThe sixth edition of Operative Surgery of the Colon, Rectum and Anus presents the state of the art in colorectal surgery. Edited by world renowned surgeons and with expert chapters from contributors in North America, Europe, and Australasia, the book is essential reading for the experienced surgeon established in colorectal practice as well as advanced trainees in general surgery. Each procedure is described in authoritative text beautifully complemented by high quality step-by-step color artwork and intraoperative photographs, enabling the reader to approach common and rare colorectal conditions with confidence.The book comprehensively covers surgery of the anus, rectum and colon in 87 chapters, grouped into nine sections for ease of reference (General Principles, Proctology, Stomas, Small Intestine, Colon, Rectum, Perineal Reconstruction, Rectal Prolapse and Surgery for Incontinence). The print edition is further enhanced by an accompanying VitalSource eBook, enablinTrade Review"…the editors have succeeded in their stated aim to produce a definitive contemporary textbook of operative colorectal surgery. I think a copy should be available in any hospital library where colorectal surgery is performed…"—Colorectal DiseaseTable of ContentsGeneral Principles. Preparation for colorectal surgery .Safety and positioning in the operating room. Access to abdominal cavity – open. Access to abdominal cavity – laparoscopic. Access to abdominal cavity – hand-assisted laparoscopic surgery. Single incision laparoscopic-assisted colectomy. Access to the abdominal cavity: natural orifice transluminal endoscopic surgery. Anastomotic technique – suture. Anastomotic technique – stapled. Specimen handling. Proctology. Office/outpatient set up. Proctosigmoidoscopy. Flexible endoscopy. Treatment of uncomplicated haemorrhoids. Excision of perianal thrombosis. Open hemorrhoidectomy. Closed hemorrhoidectomy. Stapled hemorrhoidopexy. Perianal sepsis. Anal fistula. Rectovaginal fistula repair. Anal fissure. Anoplasty. Perianal condyloma and anal intraepithelial neoplasia. Perianal skin and anal cancer Pilonidal disease. Stomas. Ileostomy. Colostomy. Stoma closure. Antegrade continence enema procedure in children. Antegrade continent enema procedure in adults. Small intestine. Small bowel resection. Meckel’s diverticulum. Malrotation. Intestinal stricturoplasty. Adhesiolysis. Colon. Appendicectomy – open. Appendicectomy – laparoscopic. Right colectomy – open. Right hemicolectomy – laparoscopic. Right hemicolectomy – hand-assisted laparoscopic surgery. Left colectomy – open. Left hemicolectomy – laparoscopic. Left hemicolectomy – hand-assisted laparoscopic surgery. Colectomy – complete mesocolic excision. Total colectomy – laparoscopic. Total colectomy – HALS. Hartmann’s procedure. Emergency colectomy. Colonic stenting. Rectum. Anterior resection of the rectum. Anterior resection – laparoscopic . Anterior resection – hand-assisted laparoscopic surgery. Anterior resection – robotic. Coloanal anastomosis with intersphincteric resection and colon J-pouch construction. Proctocolectomy for inflammatory bowel disease – open. Proctocolectomy for irritable bowel disease – laparoscopic. Continent ileostomy (Kock reservoir ileostomy). Restorative proctocolectomy with ileal reservoir .Abdominoperineal excision of the rectum and anus. Operative technique for pelvic exenteration. Pelvic exenteration: radical perineal approaches and sacrectomies. Lateral pelvic lymph node dissection in low rectal cancer. Transanal resection for rectal lesions. Transanal endoscopic microsurgery. Presacral resections – Kraske. Surgery for Hirschsprung’s disease. The APPEAR procedure. Vertical reduction rectoplasty for idiopathic megarectum. Perineal reconstruction. VRAM flap. Martius flap. Local advancement flaps. Rectal prolapse. Delorme operation. Perineal rectosigmoidectomy. Abdominal rectopexy – open. Abdominal rectopexy – laparoscopic. Laparoscopic ventral rectopexy. STARR. The EXPRESS procedure. Surgery for incontinence. Surgical repair of the anal sphincters following injury. Sacral nerve stimulation. Construction of an electrically stimulated gracilis neoanal sphincter. Artificial bowel sphincter.

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Book SynopsisOral Medicine and Pathology at a Glance, 2nd Edition offers a comprehensive overview of essential aspects of oral medicine and pathology, with an emphasis on oral health care provision in general practice. Updated new edition, covering the most important conditions and commonly encountered oral pathologies and their clinical management Presented in the popular, highly-illustrated At a Glance style with clinical photographs throughout Written by an international author team Includes a companion website with self-assessment MCQs, further reading and downloadable images Table of ContentsPreface vii About the Companion Website viii 1 Examination of extraoral tissues 2 2 Examination of mouth, jaws, temporomandibular region and salivary glands 4 3 Investigations: Histopathology 6 4 Investigations: Microbiology 8 5 Investigations: Imaging 10 6 Investigations: Blood tests 12 7 Anatomical variants and developmental anomalies 14 8 Blisters 16 9 Blisters, infections: Herpes simplex virus 18 10 Blisters, infections: Varicella zoster virus 20 11 Blisters, skin diseases: Pemphigus 22 12 Blisters, skin diseases: Pemphigoid 24 13 Pigmented lesions 26 14 Pigmented lesions: Ethnic pigmentation and tattoos 28 15 Pigmented lesions: Melanotic macule 30 16 Pigmented lesions: Nevus and others 32 17 Pigmented lesions: Malignant melanoma 34 18 Red and purple lesions 36 19 Red and purple lesions: Desquamative gingivitis, mucositis 38 20 Red and purple lesions: Erythematous candidosis 40 21 Red and purple lesions: Angiomas 42 22 Red and purple lesions: Proliferative vascular lesions, Kaposi sarcoma 44 23 Red and purple lesions: Erythroplakia 46 24 Red and purple lesions: Erythema migrans (lingual erythema migrans; benign migratory glossitis; geographical tongue; continental tongue) 48 25 Swellings: Hereditary conditions, drug‐induced swellings 50 26 Swellings: Infections, Human Papilloma Virus 52 27 Swellings: Granulomatous conditions 54 28 Swellings: Reactive lesions 56 29 Swellings: Malignant neoplasms, oral squamous cell carcinoma (OSCC) 58 30 Swellings: Malignant neoplasms, lymphoma, metastatic neoplasms 60 31 Ulcers and erosions: Local causes, drug‐induced ulcers 62 32 Ulcers and erosions: Aphthae 64 33 Ulcers and erosions: Aphthous‐like ulcers 66 34 Ulcers and erosions: Blood diseases, gastrointestinal disorders 68 35 Ulcers and erosions: Infections 70 36 Ulcers and erosions: Erythema multiforme, toxic epidermal necrolysis and Stevens‐Johnson syndrome 72 37 White lesions: Candidosis (candidiasis) 74 38 White lesions: Keratosis, leukoplakia 76 39 White lesions: Hairy leukoplakia, lichen planus 78 40 Salivary conditions: Salivary swelling and salivary excess 80 41 Salivary conditions: Dry mouth 82 42 Salivary conditions: Sjögren syndrome 84 43 Salivary conditions: Sialolithiasis, sialadenitis 86 44 Salivary conditions: Neoplasms 88 45 Salivary conditions: Mucoceles, sialosis 90 46 Neck swelling 92 47 Neck swelling: Cervical lymphadenopathy in generalized lymphadenopathy 94 48 Neurological conditions: Bell palsy, and trigeminal sensory loss 96 49 Neurological conditions and pain: Local, referred and vascular 98 50 Neurological conditions and pain: Trigeminal neuralgia 102 51 Neurological conditions and pain: Psychogenic (idiopathic facial pain, idiopathic odontalgia, and burning mouth syndrome (oral dysesthesia)) 104 52 Jaw conditions: Temporomandibular pain‐dysfunction 106 53 Jaw bone conditions: Radiolucencies and radiopacities 108 54 Jaw bone conditions: Odontogenic diseases and cysts 112 55 Jaw bone conditions: Odontogenic tumors 114 56 Jaw conditions: Bone disorders 116 57 Jaw bone conditions: Fibro‐osseous lesions 118 58 Maxillary sinus conditions 120 59 Oral malodor 122 60 Human immunodeficiency virus (HIV) infection and AIDS 124 Index 128

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Book SynopsisCovers all aspects of the structure, function, neurochemistry, transmitter identification and development of the enteric nervous system The enteric nervous system is of special interest because it is the only substantial grouping of neurons outside the central nervous system that form circuits capable of autonomous reflex activity.Trade Review"As someone who has contributed extensively to our current understanding, John Furness provides an insightful and personal account that integrates a vast array of literature into a nicely illustrated and very readable book that will be of interest to anyone working in the field." Professor David Grundy, European Journal of Gastroenterology & Hepatology "Each chapter is very well written, focused on the specific topic and easily understandable. Also, the text has been widely integrated by more than sixty high-quality schemes, illustrations and drawings... Furthermore, the entire book has been well supported by classic publications and updated literature making all together more than 12000 references in all." Dr Roberto De Giorgio, Digestive and Liver DiseasesTable of ContentsChapter 1: Structure of the enteric nervous system. The enteric plexuses. Interconnections between the plexuses. Extent of the ganglionated plexuses. Intramural extensions of extrinsic nerves. Electron microscope studies. Enteric glia. The structural similarities and functional differences between regions may have an evolutionary basis. Development of the enteric nervous system. Maturation of enteric neurons and development of function. Changes in enteric neurons with aging. Summary and conclusions. Chapter 2: Constituent neurons of the enteric nervous system. Shapes of enteric neurons. Cell physiological classifications of enteric neurons. Functionally defined enteric neurons. Neurons in human intestine with equivalence to those investigated in laboratory animals. Summary and conclusions. Chapter 3: Reflex circuitry of the enteric nervous system. Evolution of ideas about enteric circuitry. Motility controlling circuits of the small and large intestine. Intrinsic secretomotor and vasomotor circuits. Assemblies of neurons. Circuits in the esophagus and stomach. Co-ordination of motility, secretomotor and vasomotor reflexes. Circuits connecting the intestine, biliary system and pancreas. Sympathetic innervation of the gastrointestinal tract. Summary and conclusions. Chapter 4: Pharmacology of transmission and sites of drug action in the enteric nervous system. Chemical coding and multiple transmitters. Transmitters of motor neurons that innervate the smooth muscle of the gut. Transmitters at neuro-neuronal synapses. Sites within the reflex circuitry where specific pharmacologies of transmission can be deduced to occur. Transmission from entero-endocrine cells to IPANs. Roles of interstitial cells of Cajal in neuromuscular transmission. Transmitters of secretomotor and vasodilator neurons. Synapses in secretomotor and vasodilator pathways. Transmitters of motor neurons innervating gastrin cells. Summary and conclusions. Chapter 5: Neural control of motility. Rhythmic activity of gastrointestinal muscle. Structure and properties of interstitial cells of Cajal. Relationship between slow wave activity and neural control. Gastric motility. Patterns of small intestine motility and their intrinsic neural control. Motility of the colon. Neural control of the esophagus. Gall-bladder motility. Sphincters. Muscle of the mucosa. Mechanism of sympathetic inhibition of motility in non-sphincter regions. Sympathetic innervation of the sphincters. Physiological effects of noradrenergic neurons on motility in undisturbed animals. Reflex activities of sympathetic neurons that affect motility. Summary and conclusions. Chapter 6: Enteric neurons and the physiological control of fluid secretion and vasodilation. Water and electrolyte secretion in the small and large intestines. Reflex control of water and electrolyte secretion. Secretion of gastric acid. Pepsinogen secretion. Gastric secretion of bicarbonate. Secretion into the gall bladder. Pancreatic exocrine secretion. Summary and conclusions. Chapter 7: Disorders of motility and secretion and therapeutic targets in the enteric nervous system. Therapeutic endpoints for motility disorders. Therapies for secretory diarrheas. Enteric neuropathies involving neuronal loss or phenotypic changes. Mitochondriopathies with intestinal manifestations. Irritable bowel syndrome and plasticity of enteric neurons. Summary and conclusions. Epilogue: the future of enteric neurobiology. References. Index.

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Book SynopsisFind relief from pain and inflammation with this complete Crohn''s disease cookbook Whether you''ve been recently diagnosed with Crohn''s disease or have been living with it for some time, a well-balanced, specialized diet can be invaluable for healing. Unlike other Crohns disease books, The Crohn''s Disease Cookbook can help you manage symptoms and flare-ups while enjoying mouthwatering meals with nutrient-rich, fresh ingredients. From tangy Lemon Chicken to classic Shepherd''s Pie, this complete Crohn''s Disease cookbook (and two-week meal plan) delivers everything you need to start feeling better every day. Personalize your approach to eating with symptom tracking, shopping lists for stocking an IBD-friendly kitchen, and more. Eating well and feeling your best while managing your condition is clearer and easier with one of the most comprehensive Crohns disease books. This standout among Crohns disease books features: 100 Soothing recipesDiscover dozens of delicious ways to manage Crohn''s Disease, including detailed tips for boosting nutrition and making dishes gentler on the system. Customized plansGet expert guidance on what to eat and avoid, plus two weekly meal plans to address eating for flare-ups and remission. The latest scienceExplore the most up-to-date data available for treating IBD and the effects of food on symptoms in this essential selection within Crohns disease books. Go beyond other Crohns disease books with this all-in-one cookbook for people living with Crohn''s disease.

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Book SynopsisFree digital access available with every print purchase. See inside the book for more details.While classification of pancreatic neoplasms has not evolved significantly since 2007, data related to the molecular underpinnings that characterize each type of neoplasm have grown exponentially in the past 15 years. The current multimodal study of pancreatic neoplasms has allowed a better understanding of tumor biology, more closely linking the mor¬phologic findings with clinical outcomes and targeted treatment. The prognosis of conventional pancreatic ductal adenocarcinoma remains very poor, but some promise is on the horizon based on novel treatment approaches and the increase in earlier diagnosis. Furthermore, intensive study of other pancreatic neoplasms has led to a clearer recognition that each type has distinctive biology and behavior that is often not so highly aggressive. This sense of optimism may help drive a resurgence of interest in pancreatic pathology.

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Book SynopsisDespite greater emphasis on cross-sectional imaging techniques such as CT and MR, practical knowledge of fluoroscopy remains essential for radiologists. Practical Fluoroscopy of the GI and GU Tracts covers everything a radiology trainee or experienced radiologist needs to know about these procedures in a reader-friendly, highly illustrated volume.Trade Review'The ample number of images provided is truly a highlight and brings this already well-written text to the next level. This book is an excellent resource for practising radiologist[s] and residents alike. It provides the information needed to perform the procedures in a concise step-by-step fashion. It is concise and high-yield, making it useful as both as a primary text book as well as a reference text.' Academic Radiology'The organization and layout of content makes it easy for you to understand, retain and recall information … All in all, this is a great book in its field.' Nano Khilnani, Biz IndiaTable of ContentsPreface; Part I. GI Tract: 1. Pharynx; 2. Examination of the esophagus, stomach and duodenum: techniques and normal anatomy; 3. Esophagus; 4. Stomach; 5. Duodenum; 6. Small intestine: normal anatomy and techniques; 7. Small intestine; 8. Colon: normal anatomy and techniques; 9. Colon; Part II. GU Tract: 10. Fluoroscopic evaluation of the bladder, urethra and urinary divisions; 11. Retrograde pyelography; Index.

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Book SynopsisLiver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all cliniTable of ContentsSection 1. Pathophysiology of Pediatric Liver Disease: 1. Liver development; 2. Functional development of the liver; 3. Mechanisms of bile formation and the pathogenesis of cholestasis; 4. Acute liver failure in children; 5. Cirrhosis and chronic liver failure in children; 6. Portal Hypertension in children; 7. Laboratory assessment of liver function and injury in children; Section 2. Cholestatic Liver Disease: 8. Approach to the infant with cholestasis; 9. Medical and nutritional management of cholestasis in infants and children; 10. Neonatal hepatitis and congenital infections; 11. Biliary atresia and other disorders of the extrahepatic bile ducts; 12. Neonatal jaundice and disorders of bilirubin metabolism; 13. Familial hepatocellular cholestasis; 14. Alagille Syndrome; 15. Intestinal failure associated liver disease; 16. Diseases of the gallbladder in infancy, childhood, and adolescence; Section 3. Hepatitis and Immune Disorders: 17. Hepatitis A and hepatitis E virus in children; 18. Hepatitis B virus infection in children; 19. Hepatitis C virus infection in children; 20. Autoimmune hepatitis in children; 21. Sclerosing cholangitis in children; 22. Drug-induced liver disease in children; 23. Liver disease in immunodeficiencies in children; Section 4. Metabolic Liver Disease: 24. Laboratory diagnosis of inborn errors of liver metabolism; 25. α1-Antitrypsin Deficiency; 26. Cystic fibrosis liver disease in children; 27. Inborn errors of carbohydrate metabolism; 28. Copper metabolism and copper storage disorders in children; 29. Iron storage disorders in children; 30. Heme biosynthesis and the porphyrias in children; 31. Tyrosinemia in children; 32. Lysosomal storage disorders in children; 33. Disorders of bile acid synthesis and metabolism in children; 34. Inborn errors of fatty acid oxidation; 35. Mitochondrial hepatopathies; 36. Non-alcoholic fatty liver disease in children; 37. Peroxisomal disorders in children; 38. Urea cycle disorders in children; Section 5. Other Considerations and Issues in Pediatric Hepatology: 39. Bacterial, parasitic, and fungal infections of the liver in children; 40. Systemic disease and the liver in children; 41. Fibrocystic liver disease in children; 42. Tumors of the liver in children; 43. Liver transplantation in children: indications and surgical aspects; 44. Liver transplantation in children: post-transplant care.

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Book SynopsisAre you suffering from Irritable Bowel Syndrome? Do you have episodes of wind, bloating, constipation and diarrhoea? If so, this probably means that your digestive system is not functioning properly and you need to find out why. Based on proven methods applied in her own practice, Hilda Glickman discusses the symptoms of IBS, shows you how to test at home for the possible causes and looks at how you can improve your overall health through simple changes to your diet. Written in a clear, accessible style, this book offers a five-step plan that will enable you to Find out and eliminate what should not be in your digestive tract Add in what should be in the digestive tractFacilitate the reintroduction of beneficial bacteriaHeal and strengthen your digestive tract Learn how you should eat in order to maintain a healthy digestionYour digestive system doesn''t exist on its own. If it is not functioning correc

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Book SynopsisTo all readers of this book on pancreatitis: The idea of centering a book on pancreatitis came to the authors mind after working as a general surgeon at his hospital over a period of twenty-seven years after his return from Britain, where he finished his postgraduate training and received the fellowship from the Royal College of Surgeons of Edinburgh. This book covers topics of pancreatitis including pathology, clinical presentation, investigations and treatment; it is recommended for resident surgeons and will help them to attain knowledge on pancreatitis. The author would like to thank the staff of the HBP unit at Queen Elizabeth Hospital at Birmingham, particularly Professor J. Buckle and Mr. D. Mirza, who gave the author the chance to practice his skills when he was a visiting surgeon at their unit.

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Book SynopsisFlavonoids are plant secondary metabolites with a basic polyphenolic skeleton and anticancer properties have greatly attracted the interest of scientists already for several years. This structurally diverse group of phytochemicals can be found abundantly in various edible plant products, such as fruits and vegetables, tea and cocoa, nuts, spices, grains and medicinal herbs. In the past decades, numerous experimental studies have shown antiproliferative, proapoptotic, antiinflammatory, antiangiogenic, antiinvasive and antimetastatic activities of these compounds in different cancerous systems. Because of close contacts and interactions of ingested food components with the epithelial lining of organ sites of the upper gastrointestinal tract, flavonoids can directly affect the development and progression of malignant neoplasms in the oral cavity, esophagus and stomach. This book gives a comprehensive and contemporary survey about the different anticancer actions of various natural and semisynthetic flavonoids in experimental models of oral, pharyngeal, esophageal and gastric cancers, involving the data obtained from studies of both cell lines as well as laboratorial animals. Also, the effects of flavonoids on the therapeutic responses of conventional cancer treatment modalities, i.e., different chemotherapeutic drugs and irradiation, are presented and analyzed. Moreover, the current epidemiological knowledge about the role of dietary intake of flavonoids on the risk of carcinogenesis in the upper digestive tract in populations with different dietary and lifestyle habits is described. By virtue of the high topicality of the subject but also the thoroughness of its discussion, this book could be interesting and attractive to basic scientists working in the field of plant chemicals, molecular cancer research or design and development of novel anticancer drugs; synthetic chemists in different pharmaceutical companies; health workers and nutritional counselors; medical doctors working with cancer patients; people suffering from any type of upper digestive tract tumors and their family members; and anyone who is interested in the natural tools for the fight against malignant neoplasms and whose purpose is to consciously prevent carcinogenesis within the upper gastrointestinal tract.

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Book SynopsisAcute appendicitis is one of the most common surgical abdominal emergencies worldwide, with a lifetime risk of 8.6% for males and 6.7% for females. This compilation discusses how while non-operative treatment of appendicitis has been proposed as an alternative to surgery, appendicectomy remains the mainstay of treatment in most cases and techniques have shifted from open to laparoscopic methods. The current knowledge in pathogenesis, diagnosis, and clinical management of acute appendicitis is also discussed. Next, the authors present an updated review chapter of appendicitis regarding its prevalence and risk factors, particularly how the diagnosis of appendicitis is based on a history of diffuse abdominal pain, which usually starts in the central region of the abdomen and migrates to the lower right quadrant of the abdomen. The residual remnant or "stump" of the appendix after an initial appendectomy may become inflamed causing what is commonly referred to as stump appendicitis. Treatment with antibiotics may be attempted as an alternative to surgery; however, the vast majority of cases require definitive surgical excision of the remnant appendix. The authors propose that keeping this disease in the differential is important in reducing complications associated with delayed diagnosis.

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Book SynopsisOver past several decades, an increasing number of cases of diverticulitis of colon have been reported making it a major health problem particularly in western countries. The distribution of the disease varies geographically with western population having prevalence rates of 5-45% and Asian population having prevalence rates of 13-25%. Although elderly people are more likely to develop diverticulitis, younger patients may also develop diverticular disease. In fact, it has been reported that disease in younger patients is more aggressive with higher rates of complication and recurrence. According to latest statistical reports acute diverticulitis accounts to nearly 200000 hospital admissions putting a burden of 2.7 billion dollars on healthcare system in America. Diverticular disease can cause significant symptoms, impair quality of life and can prove fatal if left untreated and is considered as the fifth most costly gastrointestinal disorder in the Western world. The book entitled, Diverticulitis; Diagnosis and Treatment, presents an up to date review of the medical and surgical management of diverticulitis. The book comprises of various topics discussing the background, epidemiology, etiology, pathogenesis, presentation, treatment both medical and surgical, and recent advances in the management of diverticulitis. The book will be academic interest for surgeons, physicians, gastroenterologists and Coloproctologists. The book can be used as a reference book by teachers, professionals and students. The main benefit of reading this book is that since this disease entity is common all over the world and its incidence is increasing and is a significant contributor of health care costs, all the relevant and latest information regarding this disease has been published in a comprehensive form which will be helpful to the students, academicians, researchers and professionals dealing with medical healthcare.

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Book SynopsisThis book includes studies aimed at determining design interventions in which the composition of microbiota may be modulated to achieve a specific microbial profile beneficial to overall host behavior. In addition, this compilation summarises and critically discusses recent literature on the evaluation of changes in the microbiota associated with liver diseases, aiming to evaluate which alterations could be involved in the initiation and progression of liver disease. The authors emphasize the importance of promoting a balanced microbiome to maintain or improve oral health effectively. In order to fully understand the progression of oral diseases, it is essential to evaluate the microbiome together with genetic, immunological and environmental factors.Table of ContentsPreface; The Effect of Gut Microbiota Alterations in the Gut-Brain Axis and Its Contribution to the Obesogenic State: An Overview; Insights into the Role of Dysbiosis in the Progression of Liver Disease: An Update; Oral Microbial Dysbiosis; Index.

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Book SynopsisInflammatory bowel disease is a heterogeneous group of chronic, idiopathic, immune-mediated, inflammatory disorders of the gastrointestinal tract, including Crohn''s disease and ulcerative colitis. In this book, the reader will find a preliminary section on the etiopathogenesis, epidemiology, and clinical-pathologic aspects of Crohn''s disease, and - bearing in mind that the best therapeutic choice begins with an accurate diagnosis - an attempt to provide an updated, comprehensive view of the state-of-the-art endoscopic and radiologic procedures used in the diagnosis, staging and management of Crohn''s disease with special emphasis on test appropriateness in the various clinical setting.

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Book SynopsisThis book examines new research on irritable bowel syndrome, also known as spastic colon, which is a functional bowel disorder characterised by chronic abdominal pain, discomfort, bloating and alteration of bowel habits in the absence of any organic cause. As discussed in this book, although there is no known cure, symptoms can often be relieved through bowel movements and through certain treatments including dietary adjustments, medication and psychological interventions. Irritable bowel syndrome may begin after an infection or a stressful life event. However, the exact cause of irritable bowel syndrome is unknown. This book examines the most common theory, which states that it is a disorder of the interaction between the brain and the gastrointestinal tract, although there may also be abnormalities in the gut flora or the immune system as well. Some researchers have also suggested that irritable bowel syndrome is a type of low-grade inflammatory bowel disease.

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Book SynopsisIn this book, the authors present topical research in the study of the causes, treatment and prevention of liver disease and peritonitis. Topics discussed include abnormal circulating adiponectin levels which are closely associated with the development of chronic liver disease; systemic immuno-inflammatory response to severe peritonitis; the pathogenesis and therapy of peritonitis in cirrhosis; ethnic disparities in liver diseases and alteration of adhesion molecules expression and cellular polarity in liver disease.

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Book SynopsisIrritable bowel syndrome (IBS) is common and affects 5 to 20% of individuals world-wide. Physicians with various specialties and at different settings are bound to meet these patients. This book is written by clinicians with long experience with IBS patients at different settings that have performed active research on IBS from different angles. Topics discussed include the prevalence and incidence of IBS world-wide, symptoms and consequences for patients and the society; IBS symptom based diagnosis; pathogenesis and the different possible etiological factors; a new hypothesis for the pathogenesis of IBS; post-infectious and inflammatory bowel disease (IBD) associated IBS and treatment options, both non-pharmacological and pharmacological. This book does not only contain up to date data, but also included are the authors'' points of view and their argument in several debated issues in IBS.

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Book SynopsisGastroenteritis is marked by inflammation of the gastrointestinal tract involving both the stomach and small intestine, and resulting in diarrhoea, vomiting, and abdominal cramps. Globally, it is estimated that 3-5 billion cases of gastroenteritis occur yearly primarily affecting children and those in the developing world. In this book, the authors present research in the study of the epidemiology, management and prevention of gastroenteritis. Topics discussed include benign infantile convulsions associated with mild gastroenteritis; the etiologic agents of viral gastroenteritis; traveller''s diarrhoea; and eosinophilic and E. coli gastroenteritis.

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Book SynopsisUlcerative colitis is a chronic inflammatory disorder of the gastrointestinal tract, primarily confined to the colon and rectum. The clinical manifestations are characterised by diarrhoea, rectal bleeding, passage of mucus and pus and abdominal cramping. This book presents current research in the study of the symptoms, treatment and complications of ulcerative colitis. Topics include treatment of steroid-dependent ulcerative colitis; the pathogenesis and neutrophil-derived defensin in ulcerative colitis; and the role of gastrointestinal granulocytes in inflammatory bowel disease.

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Book SynopsisThis book presents current research in the study of oesophageal cancer. Topics discussed include epidemiology and risk factors; helicobacter pylori infection and oesophageal cancer; celiac disease and the risk of oesophageal cancer; radiation therapy of oesophageal tumours; endoscopic ultrasound in oesophageal carcinoma; minimally invasive esophagectomy versus open techniques; esophagectomy for advanced stage esophageal cancer and surgical treatment of cervical oesophageal cancer.

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Book SynopsisThis book adheres to strict scientific principles and is designed to explore the whole aspect of gallstone disease from the micro world of genetic profiles, basic metabolisms of bile lipids in cholesterol gallstone patients, to the macro world of clinical triple defects of gallstone patients. It is especially suitable for medical professionals: internists, surgeons, residents, nurses and medical students, and for collection by libraries. This book contains updates of recent breakthroughs and developments in the genetic factors affecting cholesterol gallstone formation including genes for ABCB11, ABCG5/G8, GPBAR1, OSTα/OSTβ, Megalin and Cubilin proteins. It also covers basic metabolisms of bile lipids in relation to stone formation, and some aspects of the epidemiology, classifications, chemical and crystallography of gallstones.

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Book SynopsisThis book adheres to strict scientific principles and is designed to explore the whole aspect of gallstone disease from the micro world of the genetic profiles, basic metabolisms of bile lipids in cholesterol gallstone patients, to the macro world of clinical triple defects of gallstone patients. It is especially suitable for medical professionals: internists, surgeons, residents, nurses and medical students, and for collection by libraries. This book deals with motor dysfunction in calculous gallbladders as well as reactive oxygen species in relation to gallstone formation. Aetiology and pathogenesis of pigment, calcium carbonate and intra-hepatic gallstones are also discussed.

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Book SynopsisInfection by Helicobacter pylori has for many years been one of the medical conditions most studied not only in the gastroenterological context. This is because, in recent years, H. pylori has also been involved in a number of extra-intestinal diseases. In this book, we have tried to involve the biggest international experts on the subject. Some authors have tried to provide a complete view of the most common and widely used diagnostic methods, both invasive and non-invasive, also explaining the unusual techniques and the most innovative complementary methods not yet used in clinical practice. Other international experts have tried to describe the latest findings on pathogenesis and the various clinical manifestations of infection by H. pylori in the various systems. One chapter is reserved for H. pylori infection in childhood, an important period especially in transmission of the infection, explaining the various international guidelines for correct diagnosis and treatment. The authors have also provided the latest evidence regarding the various methods of eradication therapy, with a critical analysis of the reasons that compel some researchers to believe that eradication at all costs is not always correct and useful for humans. The book also deals with the current and latest knowledge regarding the progress and the difficulties in the development of a vaccine against H. pylori infection, the implementation of which could solve the problem of the difficulty in the eradication linked mainly to the onset of antibiotic-resistance.

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Book SynopsisBarrett''s oesophagus refers to an abnormal change or metaplasia in the cells of the lower portion of the oesophagus. When the normal squamous epithelium lining of the oesophagus is replaced by goblet cells, Barrett''s oesophagus is diagnosed. The medical significance of Barrett''s oesophagus is its strong association with oesophageal adenocarcinoma, a particularly lethal cancer. In this book, the authors discuss the risk factors, diagnosis and management of Barrett''s oesophagus. Topics include chemoprevention strategies including aspirin and non-steriodal inflammatory agents in treating Barrett''s oesophagus; an endoscopic ablative technique used in the management of Barrett''s oesophagus and early oesophageal cancer; a histopathological analysis of protease activated receptor-2 (PAR-2) and cyclooxygenase-2 (COX-2) immunoexpression in oesophageal glandular metaplasia; and the impact of inflammation-metaplasia-adenocarcinoma sequence and inflammatory microenvironment in oesophageal carcinogenesis using surgical rat models.

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Book SynopsisShort bowel syndrome (SBS) is defined as intestinal failure following a loss of intestinal length which causes marked maldigestion and malabsorption of dietary nutrients and induces major faecal issues, loss of energy, nitrogen, and fat. Intestinal failure and SBS continue to be important clinical problems due to their high mortality and morbidity rates, as well as their devastating socio-economic effects. Although intestinal transplantation has emerged as a feasible alternative in the treatment of children with SBS in the last two decades, intestinal adaptation remains the only chance for survival in a subset of these patients. Intestinal adaptation is defined as a process of progressive recovery from intestinal failure following bowel resection. In this book, the aetiology of SBS, its pathophysiology, and the cellular and molecular mechanisms of intestinal adaptation are reviewed. The most common complications of SBS, including intestinal failure associated liver disease and sepsis, are outlined with strategies to reduce them. The potential role of tissue engineering for SBS that go beyond the "simple" generation of the tubular small intestine is discussed. Such knowledge will likely provide the basis for further advances in the treatment of patients with short bowel syndrome and suggest new therapeutic strategies to maintain gut integrity, eliminate the dependence on total parenteral nutrition, and avoid the need for intestinal transplantation.

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Book SynopsisIn recent years mass media represented an important vehicle to develop the concept that everything we eat could have a positive or negative impact on our health; diet may modulate various physiological functions and may play destructive or beneficial roles in some diseases. On the other hand, numerous researchers support the concept that the maintenance of healthy gut microflora may provide protection against gastrointestinal disorders including infections and inflammatory bowel diseases. All of this information has increased the interest of consumers in their personal health and consequently toward healthy or organoleptic characteristic of foods. Consumers demand foods having a "medicinal value" and able to prevent illness and to modulate the intestinal microflora using live adjuncts micro-organisms called "probiotics". The selection of probiotics is based on some general microbiological criteria such us safety, health benefits, technological and digestive stress survival, intestinal cell adhesion and human origin. This book provides information on how this is done; discusses the efficacy of probiotics in preventing and treating microbial infections; the relation of probiotics and gastrointestinal diseases; enterococci; and the role of probiotics on immune mediated disorders.

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Book SynopsisGastric cancer is one of the leading causes of malignancy-related deaths world-wide with differences in incidence and treatment patterns geographically. There is extensive ongoing research for a better understanding of the cancer pathology and finding newer treatments. Advancements in basic science research are being translated for improving gastric cancer patient care. This book discusses an extensive array of different topics on gastric cancer in which strides of improvement have been achieved. The contributors of each specialised chapter of the book are leaders in their field and have been recognised for their work globally. This book aims to bring the readers up to date about all aspects of gastric cancer - from basic science research about animal models of gastric cancer, to pathophysiology, staging systems, different adjuvant therapies and surgical treatment options for gastric cancer. The newer treatment options of endoscopic mucosal resections and bursectomy are described in detail. The current statuses, debates and ongoing controversies in addition to the advancements on different aspects of gastric cancer research are discussed. The book is an invaluable resource of information on all aspects of gastric cancer with the latest advancements.

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Book SynopsisAppendicitis remains one of the most common surgical emergencies, with approximately 200,000 annual cases in the United States and a lifetime risk of 8%. The treatment of appendicitis has evolved significantly, from the first reported appendectomy in 1736 at St. George''s Hospital in London. This book discusses several topics on appendicitis including the surgical management of appendicitis; pediatric advanced appendicitis; acute appendicitis; treatment strategies; risk factors and clinical implications.

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Book SynopsisUncommon gastrointestinal diseases are a worrisome and challenging problem for gastroenterologists and GI Pathologists. In this book, the authors present research in the study of the epidemiology, management and prevention of uncommon gastrointestinal diseases (eg: isolated gastroduodenal Crohn''s disease, primary lymphangiectasis of intestine, microscopic colitis, eosinophilic gastroenteritis, solitary rectal ulcer syndrome and primary splenic epithelial cysts). This book is definitely useful for gastroenterologists and GI pathologists for the diagnosis, treatment and prevention of these uncommon conditions.

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Book SynopsisIntussusception is the most frequent cause of bowel obstruction in infants and toddlers. In this book, the symptoms and clinical findings of intussuception are discussed. The clinical guidelines for the management of intussuceptions in children are discussed as well. Other chapters examine the diagnosis, etiology, pathophysiology and treatment modalities for both small bowel obstruction and intussusception of the small bowel, focusing on minimally invasive surgical options; the etiology of afferent loop obstruction; the treatment options for adhesive small bowel obstruction (SBO), a common complication typically caused by adhesions that form after abdominal surgery; a literature review of traditional medical treatment options and a discussion on the authors'' experiences in treating gynaecological cancer patients with non-malignant bowel obstruction using manual physical therapy.

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