Endocrinology Books

Book SynopsisTrade Review"Izabella has healed herself and thousands of others and compiled her evidence-based approach in this must-have manual for reversing symptoms. Filled with success stories, personalized approaches, recipes and more, HASHIMOTO'S PROTOCOL is the book that all those suffering from thyroid symptoms have been waiting for." -- Dana Trentini, founder of the thyroid advocacy blog hypothyroidmom.com "Dr. Izabella Wentz is my go to resource for thyroid disease. Her new book, HASHIMOTO'S PROTOCOL, is a user-friendly guide that will help you take charge of your health and heal from Hashimoto's." -- JJ Virgin, CNS, CHFS Celebrity Nutrition & Fitness Expert and author of the NYT bestsellers The Virgin Diet and Sugar Impact Diet "Discover effective protocols, success stories, and recipes that you can use to get your health back. HASHIMOTO'S PROTOCOL lets you take charge of your health!" -- Dr. Sara Gottfried M.D., NYT bestselling author of The Hormone Cure and The Hormone Reset Diet "Dr. Izabella Wentz guides you through the HASHIMOTO'S PROTOCOL to reduce symptoms and improve your health - reducing or removing the need for medication and, in some cases, eliminating the autoimmune attack completely! This book offers real solutions, and hope, to those suffering from thyroid disease." -- Katie Wells, Founder of WellnessMama.com and award-winning blogger, author, podcaster and real food crusader "I wish Dr. Izabella Wentz's HASHIMOTO'S PROTOCOL was in my hands when I was hacking my own Hashimoto's. Dr. Wentz spent years researching and perfecting her treatment on herself and thousands of patients. There is simply no better guide to Hashimoto's than this book." -- Dave Asprey, founder and CEO of Bulletproof, author of The Bulletproof Diet "Izabella has healed herself and thousands of others and compiled her evidence based approach in this must-have manual for reversing symptoms. Filled with success stories, personalized approaches, recipes and more, HASHIMOTO'S PROTOCOL is the book that all those suffering from thyroid symptoms have been waiting for." -- Dana Trentini, founder of the thyroid advocacy blog hypothyroidmom.com "HASHIMOTO'S PROTOCOL is an essential book for anyone with Hashimoto's. Dr. Wentz has created a 90-day program from her clinical training, personal experience, careful research, and feedback from thousands of fans. I've seen countless people follow her advice and regain energy, improve autoimmunity, lose weight, and regrow hair." -- Alan Christianson, NMD, NY Times bestselling author of The Adrenal Reset Diet and founder of the Integrative Health Clinic "In HASHIMOTO'S PROTOCOL, Dr. Wentz presents an evidence-based, practical approach to treating Hashimoto's 'from the inside out'. Instead of just suppressing symptoms with drugs. Dr. Wentz will show you how to address the underlying causes so you can truly heal." -- Chris Kresser, MS, LAc, founder of Kresser Institute for Functional & Evolutionary Medicine, creator of ChrisKresser.com and Revolution Health Radio, NY Times bestselling author of The Paleo Cure "Dr. Wentz brings a focused study of Hashimoto's to her latest book, and a sensible, achievable plan born of her own experience as a Hashimoto's patient who has gone from struggling to thriving. With her unique vantage point, she is leading the way for others to do the same." -- Aviva Romm, MD, author of The Adrenal Thyroid Revolution and Botanical Medicine for Women's Health

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Book SynopsisOffering safe and practical nutritional and healthcare advice this book is vital for all women wishing to overcome the pain of endometriosis.Endometriosis is the condition in which the lining of the womb grows on other organs outside of the uterus, frequently causing intolerable pain. In some cases it may lead to problems conceiving or infertility. However, there is relief for this condition as Dian Shepperson Mills illustrates in this book.Endometriosis is a detailed, insightful look at a disease which affects approximately one in ten women worldwide. Drawing upon years of research, Dian Mills and Michael Vernon show how the right diet can provide the key to optimum health in overcoming endometriosis.This book contains:An explanation of how endometriosis affects the body and advice on how to cope with it.An account of the key role played by nutritious and healthy food.Information on foods that are harmful and foods with healing qualities.Delicious recipes and practical menu suggestio

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Book SynopsisThe Harvard-educated physician and New York Times bestselling author of The Hormone Cure shows you how to grow new receptors for your seven metabolic hormones, making you lose weight and feel great fast!When it comes to weight loss, most people don’t think about hormones.Trade Review"The Hormone Reset Diet may be just what we need to end dieting for women." -- Mark Hyman, New York Times bestselling author of The Blood Sugar Solution Praise for The Hormone Reset Diet: "The Hormone Reset Diet is a breakthrough hormone guide?entertaining, persuasive, hilarious. I've not seen this content anywhere! Get to the root of your issues: low energy, fatigue, low sex drive, anxiety, weight gain. This book is gold." -- Marci Shimoff, author of Love for No Reason Praise for The Hormone Reset Diet: "The Hormone Reset Diet is a breakthrough hormone guide?entertaining, persuasive, hilarious. I've not seen this content anywhere! Get to the root of your issues: low energy, fatigue, low sex drive, anxiety, weight gain. This book is gold." -- Danielle LaPorte, author of The Fire Starter Sessions "Never before have I read a book and shouted, 'Oh my God, that's ME!' Managing hormones is the most important issue of women my age. I don't just want to read Sara Gottfried, I want her to be my doctor, my friend, and my sister." -- Ayelet Waldman, author of Red Hook Road and Bad Mother "This wonderful book transforms how we approach women's health issues, and will help you understand how to achieve hormonal equilibrium if you suffer from fatigue, depression and other endocrine-based neuropsychiatric symptoms." -- Jay Lombard, DO, author of Balance your Brain, Balance your Life "Dr. Sara is smart, she's hip, and yet she's pure Harvard! Learn how to make your hormones hum. Run, don't walk, to buy this book-for yourself and your friends. The life you save may be your own." -- Hyla Cass, MD, author of 8 Weeks to Vibrant Health "A magnificent book! Every woman needs to read it, and every doctor." -- Louann Brizendine, MD, Author, The Female Brain and The Male Brain "Don't accept the hormonal hell of being tired, stressed, fat, never in the mood for sex. Dr. Gottfried gives you an effective, easy-to-follow plan to balance your hormones and become lean and energetic. Stop settling, reclaim your sexy!' -- JJ Virgin, author of Six Weeks to Sleeveless and Sexy "Occasionally a book comes along that's perfect for its time-on topic, written with authority. Such is the book by Sara Gottfried, MD. It is a definitive integration of safe and effective approaches to the management of menopause." -- Jeffrey Bland, PhD, author of The 20 Day Rejuvenation Diet Program "Gottfried's premise is simple: when a woman's hormones are in sync, she's a powerhouse, but when they're out of whack, they wreak havoc on her body and mind. The book is both fun and an informative read [and] Gottfried's take on the female body is eye-opening and empowering." -- Spirituality and Health magazine "Gottfried, a beautiful Harvard Medical School graduate, board-certified gynecologist, and yoga teacher, looks like an advertisement for healthy living and convincingly pushes women to make lifestyle changes rather than immediately asking for conventional prescription drugs to treat problems such as depression." -- Booklist "The Hormone Reset Diet shows us what to eat to feel and look our absolute best. No matter your age, size, or state of health, Dr. Sara Gottfried delivers sound, science-proven advice that I stand behind wholeheartedly." -- Dr. Alejandro Junger, author of the New York Times bestsellers Clean, Clean Gut, and Clean Eats "Dr. Sara Gottfried lays out all the reasons you feel like crap (hormones!) and how to get a handle on them. This is not the usual stuff you've heard over and over again, but easy, doable advice that will save you time, energy and money." -- Leanne Ely, New York Times bestselling author of the Saving Dinner series "Dr. Sara Gottfried's The Hormone Reset Diet walks you through your body's unique processes with a personalized plan for mastering your metabolism for optimal weight loss." -- Mark MacDonald, New York Times bestselling author of Body Confidence "You don't need to check your sexy in the door as you grow older. This new book is genius: Dr. Sara Gottfried redefines aging gracefully to stay lean, vibrant, and fabulous at any age!" -- JJ Virgin, New York Times best-selling author, The Virgin Diet and The Virgin Diet Cookbook "If you're tired of storing the fat you should be burning-or simply tired of stumbling through your day-then you need to read this book. Dr. Sara has the simple solutions that make lasting changes from the inside out to get you lean and give you your life back." -- Dr. Pedram Shojai, OMD, Founder, Well.Org, Author, Rise and Shine, and Producer, Vitality "When it comes to breaking new ground in understanding how to harness our hormones, nutrition, mind, and body for optimal health, Dr. Sara is out front leading the way, and thankfully, taking us along with her on this life-changing journey to better health." -- Mary Shomon, New York Times best-selling author, The Thyroid Diet Revolution "Straight from the mind of top hormone guru Dr. Sara Gottfried, The Hormone Reset Diet contains new biohacking secrets about how to eat and move to control your top seven metabolic hormones." -- Dave Asprey, bestselling author of The Bulletproof Diet Book "Dr. Sara Gottfried understands the extremely complex interplay between hormones, food and environment like no one else I know. This book is a real eye opener and I can't recommend it highly enough." -- Jon Gabriel, best selling author of The Gabriel Method and Visualization For Weight Loss "Allow the wisdom of Dr. Sara and functional medicine to come to your rescue, and heal your food addiction once and for all. It's time to reset your hormones with your fork and learn to be lean naturally." -- Mark Hyman, New York Times bestselling author of The Blood Sugar Solution "In this practical guide, Dr. Sara Gottfried teaches you what your hormones are telling you, and how to respond, so that you can be guided by the innate intelligence of your female body, to sustainable, peaceful balance with food and your weight." -- Jena la Flamme, author of Pleasurable Weight Loss: The Secrets of Feeling Great, Losing Weight and Loving Life Today. "In a world where so many have lost their way and hope when it comes to their health and body, The Hormone Reset Diet is a helpful guiding light. It's filled with great insights, helpful self-assessments, and simple tools to bring your body back to life." -- Yuri Elkaim, BPHE, RHN, NY Times best-selling author, The All-Day Energy Diet "Sara's book is just what we as women need most - a woman's perspective on what it really means to feel overwhelmed, overweight, tired, and hopeless - and a woman doctor as your guide on how to reset not just your body, but your entire relationship with food and your self." -- Aviva Romm, MD, The UltraWellness Center of Dr. Mark Hyman, Author, Botanical Medicine for Women's Health "The Hormone Reset Diet will not only allow you to lose weight, but with the right hormonal balance, you will think more clearly and feel better than ever." -- Daniel Amen, CEO of Amen Clinics and New York Times bestselling author of The Daniel Plan and Change Your Brain, Change Your Life "Feeling cranky, exhausted, and stressed shouldn't be the norm. With Sara Gottfried's practical advice, you can balance your hormones naturally-without a bunch of pills-and feel at home in your body once again. The Hormone Reset Diet holds the keys to total transformation." -- Cynthia Pasquella, founder and director of the Institute of Transformational Nutrition "Dr. Sara shares her personal journey of regaining her own health while juggling her family's needs and a demanding career. Not only does she show you that rejuvenation is possible, she gives you the insights and the recipes that will make it happen for you." -- Alan Christianson, NMD, author of The Adrenal Reset Diet "Gottfried's chatty, encouraging, woman-to-woman tone makes a very challenging diet plan seem quite doable, as does an appealing layout with boxes, illustrations, and tables. This diet guide seems certain to hit bestseller lists." -- Publishers Weekly

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Book SynopsisTrade Review“Essential reading for the many people who are overworked, burned out, running on empty, and feeling sick and tired all the time. As Dr. Gundry shows, fatigue is not your fate!” — Arianna Huffington, Founder & CEO, Thrive Global "Practical, applicable advice on how to conquer fatigue and maximize energy." — Kirkus Reviews

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Book SynopsisTrade ReviewA hands-on manual for influencing human happiness through your own biology... It doesn't get any better than this! -- Thomas Erikson, author of Surrounded by IdiotsUseful for anyone wishing to brighten up their lives -- The Sunday Times

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Book SynopsisA comprehensive guide to addressing the growing epidemic of thyroid disease from the perspective of the Ayurvedic tradition In this comprehensive guide for practitioners and those concerned with thyroid health, Marianne Teitelbaum, D.C., integrates the ancient medicine of Ayurveda with modern scientific findings to address the growing epidemic of thyroid disease. Revealing how the thyroid is the victim of many factors that conspire to create ill health--and how many cases of thyroid disease go undiagnosed--Teitelbaum focuses not only on treating thyroid problems and symptoms but also on diagnosing them at their earliest, most reversible stages. She outlines the basic principles of Ayurveda, including pulse diagnosis, a key tool for early detection, and explains the successful treatment protocols she has developed over more than 30 years of Ayurvedic practice. She details the underlying reasons for thyroid malfunction, such as inflammation, malnutrition, and toxins, and how the thyroid is connected with the health of the rest of body, including the liver and gall bladder. She explores the Ayurvedic treatment of thyroid-related conditions, such as Hashimoto’s disease, hypothyroidism, and hyperthyroidism, offering guidance on the targeted use of herbs, specific dietary recommendations, proper detoxification, and Ayurvedic recipes. She also includes treatments and remedies for common symptoms of thyroid disease, including insomnia, depression, fatigue, and osteoporosis, as well as for luxurious hair growth and weight loss. Based on the treatment of more than 90,000 patients, this book also shares success stories of thyroid healing and the scientific studies that support the author’s Ayurvedic thyroid protocols. Offering an easy-to-follow yet comprehensive guide, Teitelbaum shows that optimum thyroid health as well as overall health are within everyone’s reach.Trade Review“This excellent work beautifully blends ancient Ayurvedic wisdom and modern endocrinology with special reference to management of the thyroid gland. It is a practical guide for both practitioners and readers, helping to reveal the natural way of balancing thyroid function. I strongly recommend this book to all readers, practitioners, and students of the healing sciences.” * VASANT LAD, BAM&S, MASc, author of Ayurveda: The Science of Self-Healing *“This much-needed and timely book presents a road map to what every patient wishes for: a body in perfect balance. Our bodies are home to the greatest hormonal symphony ever played. Your thyroid is one of its conductors. Read this book, follow the guidelines, and feel your body play beautiful music, expressed as vibrant mental and physical health.” * William Sears, M.D., author of The Dr. Sears T5 Wellness Plan *“Healing the Thyroid with Ayurveda is a groundbreaking work for humanity’s wellness. At this time of massive environmental crises, Marianne’s work is necessary for cleansing and healing manifold layers of illness relating to the thyroid and endocrine system. Synthesizing Ayurveda’s ancient knowledge with scientific precision, Marianne Teitelbaum puts forth an incisive work, adding another gem to the timeless pantheon of Ayurveda’s wisdom.” * Maya Tiwari, Vedic scholar, humanitarian, and author of Ayurveda: A Life of Balance *“Healing the Thyroid with Ayurveda is finally here. Understanding the individual nature of thyroid disease is the only prescription for a cure. Now we can stop treating with blood tests and symptoms and address the source intelligently and Ayurvedically.” * John Douillard, D.C., C.A.P., author, former NBA nutritionist, and founder of LifeSpa.com *“Dr. Marianne Teitelbaum’s new book on thyroid healing offers a completely new and refreshing understanding of thyroid imbalance and the knowledge of how to correct it gently, safely, and fully by addressing root causes unique to each patient. I urge you to read this book and get on the path to healing yourself, your family, and--if you are a doctor--your patients with thyroid conditions. We can only hope that this is the first of many books to come from Dr. Teitelbaum. Read this one now.” * Nancy Lonsdorf, M.D., author of The Ageless Woman and A Woman’s Best Medicine *“Healing the Thyroid with Ayurveda is a most useful guide to anyone interested in holistic health care. Dr. Marianne Teitelbaum challenges the insufficient modern approaches to treating thyroid dysfunction by pointing to the root causes of the disease and sharing her success with treating it through the methods of a time-tested and science-proven ancient practice. This book is so important! It will intrigue if not revolutionize the way both patients and doctors address disease.” * Divya Alter, author of What to Eat for How You Feel *“Dr. Marianne Teitelbaum embodies all the wisdom and experience of a great Ayurvedic sage. She explains in language easy enough for the layperson to understand, yet detailed enough for the seasoned practitioner, exactly what we need to do to counteract the alarming epidemic levels of thyroid problems. Going beyond the use of toxic pharmaceuticals and nutraceuticals, Dr. Teitelbaum once and for all gives us a truly natural approach to healing the thyroid gland, sharing her deep knowledge of Ayurvedic herbs, detox recipes, and healing spices. This is a must-read for anyone who is seeking help with their thyroid health. Bravo!” * Lissa Coffey, author of Song Divine: A New Lyrical Rendition of the Bhagavad Gita, *“Finally, a book that describes how to treat thyroid disorders without the use of pharmaceuticals or nutraceuticals, using an approach that goes beyond all other thyroid books on the market. If you’re seeking natural treatments for your thyroid problems, this is the one book to read this year.” * Hari Sharma, M.D., physician and coauthor of Ayurvedic Healing and Contemporary Ayurveda *“This is the first and most important definitive Ayurvedic contribution on thyroid disease in the West. It is a testimonial to the work of her teacher and mentor, Vaidya Rama Kant Mishra, and his family’s lineage of Shaka Vansya Ayurveda.” * Bill Dean, M.D., author of IC Bladder Pain Syndrome *"Healing the Thyroid with Ayurveda is a critically important and unreservedly recommended addition to personal, community, college, and university library Alternative Medicine collections in general, and Thyroid Treatment supplemental studies lists in particular." * Midwest Book Review *"This reference book gives power back to the individual, illustrating that optimum thyroid health as well as overall good health is within our reach, empowering us to further our own healing or to help others on their journey." * Nexus Magazine, June/July 2019 *"Based on her 30 years of practice, Chiropractor Teitelbaum offers successful protocols to treat symptoms associated with the thyroid, such as insomnia, depression, fatigue, osteoporosis, and hair, and weight loss. The references list many scientific citations, but rather than focus on the studies, such as how ashwagandha (Withania somnifera) modulates the thyroid. The goal is general good health achieved through balancing the three Ayurvedic doshas, or constitutions. She also delves into what causes thyroid problems and how to avoid them in the first place. It is admirable and very helpful to the herb world to write these unique book that tackles such a specific condition, especially one that has relatively few natural treatments!" * Kathi Keville, American Herb Association Quarterly Director *Table of ContentsForeword by Anjali Grover, M.D. Acknowledgments Preface INTRODUCTION Traditional Healing for a New Age 1 What Is Ayurveda? 2 The Thyroid Gland and Endocrine System 3 The Root Causes of Thyroid Malfunction 4 Thyroid and Adrenal Interactions 5 Hashimoto’s Thyroiditis: Autoimmune Disease of the Thyroid Gland 6 Gallbladder Function and the Thyroid Gland 7 Ayurvedic Treatments for Specific Conditions Caused by Thyroid Dysfunction 8 Diet and Daily Routine for Thyroid Health CONCLUSION Visionary Medicine Resources References Index

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Book SynopsisThis 7th edition is a milestone in the series of Inborn Metabolic Diseases (IMD), recognised as the standard textbook for professionals involved in the diagnosis and management of IMD.Within the last 5 years a Copernican revolution in our understanding of IMD has changed the definition, concepts, paradigms, and classification. This new edition now extends the concept of IMD to include those disturbances in molecular machinery diagnosed by molecular techniques but currently without measurable metabolic markers.The book presents a clinical and biochemical approach to the diagnosis and management of IEM with many diagnostic algorithms for patients of all ages and with a particular focus on neurological presentations. It includes separate, comprehensive sections on IEM classified in 3 major pathophysiological categories: disorders of energy metabolism, both mitochondrial and non-mitochondrial; small molecule disorders, mostly diagnosed with metabolic markers; and complex molecules disorders, mostly diagnosed with molecular techniques.Two new chapters were added, describing around 600 disorders of nucleic acid metabolism, tRNA metabolism, ribosomal biogenesis, and cellular trafficking.Table of ContentsI Diagnosis and treatment: General principles: 1 Clinical Approach to Inborn Errors of Metabolism in Paediatrics.- 2 Inborn Errors of Metabolism in Adults: A Diagnostic Approach to Neurological and Psychiatric Presentations.- 3 Diagnostic Procedures.- 4 Emergency Treatments II Disorders of Energy Metabolism 5 The Glycogen Storage Diseases and Related Disorders.- 6 Congenital Hyperinsulinism and Genetic Disorders of Insulin Resistance and Signalling.- 7 Disorders of Glycolysis and the Pentose Phosphate Pathway.- 8 Disorders of Glucose and Monocarboylic Acid Monocarboxylate Transporters.- 9 Disorders of Creatine Metabolism.- 10 Disorders of the Oxidative Phosphorylation .- 11 Disorders of Pyruvate Metabolism and the Tricarboxylic Acid Cycle.- 12 Disorders of Mitochondrial Fatty Acid Oxidation and Riboflavin Metabolism.- 13 Disorders of Ketogenesis and Ketolysis III Small Molecule Disorders 14 Disorders of Galactose Metabolism.- 15 Disorders of Fructose Metabolism.- 16 Hyperphenylalaninaemia.- 17 Disorders of Tyrosine Metabolism.- 18 Branched-chain Organic Acidurias/Acidaemias.- 19 Disorders of the Urea Cycle and Related Enzymes.- 20 Disorders of Sulfur Amino Acid Metabolism.- 21 Disorders of Ornithine and Proline Metabolism.- 22 Cerebral Organic Acid Disorders and Other Disorders of Lysine Catabolism.- 23 Nonketotic Hyperglycinaemia and Lipoate Deficiency Disorders.- 24 Disorders of Glutamine, Serine and Asparagine Metabolism.- 25 Disorders of Amino Acid Transport at the Cell Membrane.- 26 Cystinosis.- 27 Biotin-Responsive Disorders.- 28 Disorders of Cobalamin and Folate Transport and Metabolism.- 29 Disorders of Thiamine and Pyridoxine Metabolism.- 30 Disorders of Neurotransmission.- 31 Disorders of Peptide and Amine Metabolism.- 32 Disorders of Purine and Pyrimidine Metabolism.- 33 Disorders of Haem Biosynthesis.- 34 Disorders in the Transport of Copper, Iron, Magnesium, Manganese, Selenium and Zinc IV Complex Molecule Disorders and Cellular Trafficking Disorders 35 Disorders of intracellular triglycerides and phospholipid metabolism.- 36 Inborn Errors of Lipoprotein Metabolism Presenting in Childhood.- 37 Disorders of Isoprenoid/Cholesterol Synthesis.- 38 Disorders of Bile Acid Synthesis.- 39 Disorders of Nucleic Acid Metabolism, tRNA Metabolism and Ribosomal Biogenesis.- 40 Disorders of Sphingolipid Synthesis, Sphingolipidoses, Niemann-Pick Disease Type C and Neuronal Ceroid- Lipofuscinoses.- 41 Glycosaminoglycans and Oligosaccharides Disorders: Glycosaminoglycans Synthesis Defects, Mucopolysaccharidoses, Oligosaccharidoses and Sialic Acid Disorders.- 42 Inborn Errors of Non-Mitochondrial Fatty Acid Metabolism Including Peroxisomal Disorders.- 43 Congenital Disorders of Glycosylation, Dolichol and Glycosylphosphatidylinositol Metabolism.- 44 Disorders of Cellular Trafficking V Appendices 45 Medications Used in the Treatment of Inborn Errors

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Book Synopsis'Every page of this book is fascinating, glorious, and profound. This is one of the great frontiers of science for our age'Daniel M. Davis, author of The Beautiful Cure and The Secret Body  ________________________________________________From a world-leading hormones specialist, the definitive book on the science of hormones and how understanding the secrets of our body’s messengers can revolutionise our health and wellbeing   Hormones are the messengers that drive every process in our body. They are essential to how we grow, fight disease and digest food; why we struggle to sleep, lose weight and manage stress – and so much more. When our hormones are imbalanced this can wreak havoc on our health, leading to conditions as far reaching as diabetes, infertility and heart disease. They also influence our personalities, how we feel and even the decisions we make. And yet for t

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Book SynopsisThyroid problems affect an estimated one in three of the adult population, yet they are difficult to diagnose on the basis of blood tests and often go undiagnosed for many year. This is the second, greatly updated and revised, edition of Dr Durrant-Peatfield's practical guide to recognizing the signs and symptoms of thyroid disease and to treating the problem with diet and natural supplements, in conjunction with modern western drugs and surgery when really necessary.

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Book SynopsisConcise, portable, and user-friendly, The Washington Manual® Endocrinology Subspecialty Consult, 5th Edition, provides quick access to the essential information needed to evaluate a patient on an endocrinology subspecialty consult service or in the outpatient setting. Edited by Drs. Janet B. McGill, Julie M. Silverstein, and Sina Jasim, this bestselling manual offers state-of-the-art guidance on the history, physical exam, diagnosis, management, and follow-up for various endocrine and metabolic disorders. Ideal for residents cycling through an internal medicine subspecialty clinical rotation or for fellows who need to better understand the fundamentals, the manual is also useful as a first-line resource for internists and other primary care providers. Enables on-the-spot bedside patient diagnosis and management with quick, efficient answers to your fundamental questions about diagnosing and treating endocrine and metabolic disorders Thoroughly revised to include a greater emphasis on treatment and therapies, including coverage of new drugs and expanded content on transgender medicine and diabetes devices Uses a consistent format throughout and outlines symptoms, signs, and problems in bulleted lists for easy, everyday reference Written by specialty fellows and faculty in the Department of Medicine at Washington University School of Medicine in St. Louis   The Washington Manual® is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by Wolters Kluwer Health under license from Washington University.  

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Book SynopsisThe Hormone Type Cookbook is the everywoman’s guide to resolving hormone imbalance through food and lifestyle.Table of ContentsINTRODUCTION: Your Hormone Health Matters CHAPTER 1: The Hormone Education You Never Had CHAPTER 2 Nutrition Foundations for Hormone Balance CHAPTER 3 High Estrogen CHAPTER 4 Low Estrogen CHAPTER 5 Low Progesterone CHAPTER 6 Low Testosterone CHAPTER 7 High Androgens CHAPTER 8 Adrenal Burnout and Balancing Cortisol CHAPTER 9 Low Thyroid Resources Guide to Reducing Endocrine Disruptors Meal Plans References Acknowledgments About the Author Index

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Book SynopsisThe third edition of this important work is a timely update to the comprehensive textbook first published in 2002 and reissued in a second edition in 2010. The past few years have witnessed major developments in our understanding of diabetes and in therapeutic approaches to this disease and its numerous complications. Thus, all chapters have been significantly revised and updated with current evidence and best practices, and four brand new chapters are included, discussing the potential role of vitamin D in the pathogenesis of diabetes, peculiarities of diabetes in the elderly, oral manifestations of diabetes, and the current state of bariatric surgery.Written by an international group of experts and carefully edited by a leading authority on the subject, Principles of Diabetes Mellitus, Third Edition is an invaluable resource for researchers and physicians of all specialties, as well as medical students and investigators of all aspects of diabetes, who deal with an illness that has reached epidemic proportions.Table of ContentsPart I.- The Main Events in the History of Diabetes Mellitus.- Part II: Physiology of Glucose Metabolism.- Normal Glucose Homeostasis.- Endocrine Pancreas.- The Role of Incretins in Insulin Secretion.- Cellular Mechanisms of Insulin Action.- The Role of Brain in Glucose Metabolism.- Part III: Diagnosis and Epidemiology of Diabetes.- Diagnostic Criteria and Classification of Diabetes.- Epidemiology.- Diabetes in Culturally Diverse Populations: From Biology to Culture.- Part IV: Genes and Diabetes.- Genetics of Type 2 Diabetes: From Candidate Genes to Genome-Wide Association Analysis.- Rodent Models of Diabetes.- Part V: Diabetes Syndromes.- Type 1 Diabetes Mellitus: Epidemiology, Genetics, Pathogenesis, and Clinical Manifestations.- Type 2 Diabetes Mellitus: Epidemiology, Genetics, Pathogenesis, and Clinical Manifestations.- Maturity-Onset Diabetes of the Young: Molecular Genetics, Clinical Manifestations, and Therapy.- Diabetes in Pregnancy.- Secondary Causes of Diabetes Mellitus.- Syndromes of Extreme Insulin Resistance.- Oral Manifestations of Diabetes.- Part VI: Complications of Diabetes.- Acute Hyperglycemic Syndromes: Diabetic Ketoacidosis and the Hyperosmolar State.- Hypoglycemia in Diabetes Mellitus.- Intake of Advanced Glycation Endproducts: Role in the Development of Diabetic Complications.- Diabetic Retinopathy.- Diabetic Nephropathy.- Diabetic Neuropathy.- Peripheral Vascular Disease in Diabetes.- The Diabetic Foot.- Male Sexual Dysfunction in Diabetes Mellitus.- Gastrointestinal Manifestations of Diabetes.- Dyslipidemia: Pathogenesis and Management.- Dermatological Complications of Diabetes Mellitus: Allergy to Insulin and Oral Agents.- Part VII: Related Disorders.- Obesity – Genetics, Pathogenesis, Therapy.- Hypertension.- Coronary Artery Disease and Cardiomyopathy.- Polycystic Ovary Syndrome.- Insulin Resistance and the Metabolic Syndrome.- Diabetes and Liver Disease.- The Increased Risk of Cancer in Obesity and Type 2 Diabetes: Potential Mechanisms.- Diabetes and Sleep Disorders.- HIV Infection and Diabetes.- Part VIII: Therapy of Diabetes Mellitus – General Principles.- Glycemic Goals.- Behavioral and Educational Approaches to Diabetes Self- Management.- Dietary Therapy of Diabetes Mellitus.- Exercise in the Therapy of Diabetes Mellitus.- Therapy of Type 1 Diabetes Mellitus.- Treating Type 2 Diabetes Mellitus.- Prevention of Microvascular Complications of Diabetes – General Overview.- Psychiatric Care of the Patient with Diabetes.- Management of Diabetes and Hyperglycemia in the Hospital Setting.- The Future of Diabetes Therapy.- Part IX: Diabetes Prevention.- Prevention of Type 1 Diabetes Mellitus.- Prevention of Type 2 Diabetes Mellitus.- Part X.- Resources for Patients with Diabetes.

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Book SynopsisFree digital access available with every print purchase. See inside the book for more details.In endocrine pathology, surgical pathologists often concentrate on neoplasms at the expense of nonneoplastic disease processes. This is unfortunate as nonneoplastic endocrine disorders are many times more common in the population. As in all fields of medicine, nonneo¬plastic endocrine diseases can closely mimic the neoplastic; an awareness of all aspects of pathology underpins routine clinical practice. This Fifth Series Fascicle offers pathologists and clinicians an opportunity to develop an increased understanding of nontumor endocrine pathology in order to inform patient care.

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Book SynopsisNow in a revised and expanded second edition, this concise, straightforward and clearly written text presents the latest information on the evaluation and management of common issues and conditions in pediatric endocrinology. Endocrinologists, pediatricians, family physicians, residents, fellows and medical students will all benefit from the discussion of endocrine physiology and its application to common clinical practice. As in the original edition, the text presents the major signs and symptoms in the diagnosis and management of pediatric endocrine disorders, often allowing the practitioner to avoid an unnecessary consultation and preparing a provider for informed communication with parents of a child with an endocrine condition. The concepts covered in the text are designed to address the first 10 headings in the content outline of the Sub-board of Pediatric Endocrinology of The American Board of Pediatrics: disorders of the hypothalamic-pituitary axis, growth, calcium metabolism and bone, the thyroid gland, puberty, and the adrenal gland, among others. Concluding each chapter is a Suggested Reading section, directing the reader to outstanding larger and more detailed texts, manuscripts and websites that offer increased detail.Practical and user-friendly, Pediatric Endocrinology, Second Edition is not simply a checklist of everything that could be done but leads the reader toward a more specific goal of what should be done.Table of ContentsIntroduction to Pediatric Endocrinology: The Endocrine System.- The Evaluation of a Child or Adolescent with Possible Endocrine Disease.- Disorders of the Hypothalamic-Pituitary Axis.- The Posterior Pituitary Gland and Disorders of Vasopressin Metabolism.- Disorders of Growth.- Disorders of the Thyroid Gland.- Disorders of Calcium Metabolism and Bone.- Differences (Disorders) of Sexual Development (Differentiation).- Disorders of Puberty.- Disorders of the Adrenal Gland.- Diabetes Mellitus.- Hypoglycemia.- Obesity.- Pediatric Endocrine Emergencies.- Medications for Pediatric Endocrinology.- Laboratory Values for Pediatric Endocrinology.

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Book SynopsisThe Harvard-educated physician and New York Times bestselling author of The Hormone Cure shows you how to grow new receptors for your seven metabolic hormones, making you lose weight and feel great fast!When it comes to weight loss, most people don’t think about hormones.Trade Review"The Hormone Reset Diet may be just what we need to end dieting for women." -- Mark Hyman, New York Times bestselling author of The Blood Sugar Solution Praise for The Hormone Reset Diet: "The Hormone Reset Diet is a breakthrough hormone guide?entertaining, persuasive, hilarious. I've not seen this content anywhere! Get to the root of your issues: low energy, fatigue, low sex drive, anxiety, weight gain. This book is gold." -- Marci Shimoff, author of Love for No Reason Praise for The Hormone Reset Diet: "The Hormone Reset Diet is a breakthrough hormone guide?entertaining, persuasive, hilarious. I've not seen this content anywhere! Get to the root of your issues: low energy, fatigue, low sex drive, anxiety, weight gain. This book is gold." -- Danielle LaPorte, author of The Fire Starter Sessions "Never before have I read a book and shouted, 'Oh my God, that's ME!' Managing hormones is the most important issue of women my age. I don't just want to read Sara Gottfried, I want her to be my doctor, my friend, and my sister." -- Ayelet Waldman, author of Red Hook Road and Bad Mother "This wonderful book transforms how we approach women's health issues, and will help you understand how to achieve hormonal equilibrium if you suffer from fatigue, depression and other endocrine-based neuropsychiatric symptoms." -- Jay Lombard, DO, author of Balance your Brain, Balance your Life "Dr. Sara is smart, she's hip, and yet she's pure Harvard! Learn how to make your hormones hum. Run, don't walk, to buy this book-for yourself and your friends. The life you save may be your own." -- Hyla Cass, MD, author of 8 Weeks to Vibrant Health "A magnificent book! Every woman needs to read it, and every doctor." -- Louann Brizendine, MD, Author, The Female Brain and The Male Brain "Don't accept the hormonal hell of being tired, stressed, fat, never in the mood for sex. Dr. Gottfried gives you an effective, easy-to-follow plan to balance your hormones and become lean and energetic. Stop settling, reclaim your sexy!' -- JJ Virgin, author of Six Weeks to Sleeveless and Sexy "Occasionally a book comes along that's perfect for its time-on topic, written with authority. Such is the book by Sara Gottfried, MD. It is a definitive integration of safe and effective approaches to the management of menopause." -- Jeffrey Bland, PhD, author of The 20 Day Rejuvenation Diet Program "Gottfried's premise is simple: when a woman's hormones are in sync, she's a powerhouse, but when they're out of whack, they wreak havoc on her body and mind. The book is both fun and an informative read [and] Gottfried's take on the female body is eye-opening and empowering." -- Spirituality and Health magazine "Gottfried, a beautiful Harvard Medical School graduate, board-certified gynecologist, and yoga teacher, looks like an advertisement for healthy living and convincingly pushes women to make lifestyle changes rather than immediately asking for conventional prescription drugs to treat problems such as depression." -- Booklist "The Hormone Reset Diet shows us what to eat to feel and look our absolute best. No matter your age, size, or state of health, Dr. Sara Gottfried delivers sound, science-proven advice that I stand behind wholeheartedly." -- Dr. Alejandro Junger, author of the New York Times bestsellers Clean, Clean Gut, and Clean Eats "Dr. Sara Gottfried lays out all the reasons you feel like crap (hormones!) and how to get a handle on them. This is not the usual stuff you've heard over and over again, but easy, doable advice that will save you time, energy and money." -- Leanne Ely, New York Times bestselling author of the Saving Dinner series "Dr. Sara Gottfried's The Hormone Reset Diet walks you through your body's unique processes with a personalized plan for mastering your metabolism for optimal weight loss." -- Mark MacDonald, New York Times bestselling author of Body Confidence "You don't need to check your sexy in the door as you grow older. This new book is genius: Dr. Sara Gottfried redefines aging gracefully to stay lean, vibrant, and fabulous at any age!" -- JJ Virgin, New York Times best-selling author, The Virgin Diet and The Virgin Diet Cookbook "If you're tired of storing the fat you should be burning-or simply tired of stumbling through your day-then you need to read this book. Dr. Sara has the simple solutions that make lasting changes from the inside out to get you lean and give you your life back." -- Dr. Pedram Shojai, OMD, Founder, Well.Org, Author, Rise and Shine, and Producer, Vitality "When it comes to breaking new ground in understanding how to harness our hormones, nutrition, mind, and body for optimal health, Dr. Sara is out front leading the way, and thankfully, taking us along with her on this life-changing journey to better health." -- Mary Shomon, New York Times best-selling author, The Thyroid Diet Revolution "Straight from the mind of top hormone guru Dr. Sara Gottfried, The Hormone Reset Diet contains new biohacking secrets about how to eat and move to control your top seven metabolic hormones." -- Dave Asprey, bestselling author of The Bulletproof Diet Book "Dr. Sara Gottfried understands the extremely complex interplay between hormones, food and environment like no one else I know. This book is a real eye opener and I can't recommend it highly enough." -- Jon Gabriel, best selling author of The Gabriel Method and Visualization For Weight Loss "Allow the wisdom of Dr. Sara and functional medicine to come to your rescue, and heal your food addiction once and for all. It's time to reset your hormones with your fork and learn to be lean naturally." -- Mark Hyman, New York Times bestselling author of The Blood Sugar Solution "In this practical guide, Dr. Sara Gottfried teaches you what your hormones are telling you, and how to respond, so that you can be guided by the innate intelligence of your female body, to sustainable, peaceful balance with food and your weight." -- Jena la Flamme, author of Pleasurable Weight Loss: The Secrets of Feeling Great, Losing Weight and Loving Life Today. "In a world where so many have lost their way and hope when it comes to their health and body, The Hormone Reset Diet is a helpful guiding light. It's filled with great insights, helpful self-assessments, and simple tools to bring your body back to life." -- Yuri Elkaim, BPHE, RHN, NY Times best-selling author, The All-Day Energy Diet "Sara's book is just what we as women need most - a woman's perspective on what it really means to feel overwhelmed, overweight, tired, and hopeless - and a woman doctor as your guide on how to reset not just your body, but your entire relationship with food and your self." -- Aviva Romm, MD, The UltraWellness Center of Dr. Mark Hyman, Author, Botanical Medicine for Women's Health "The Hormone Reset Diet will not only allow you to lose weight, but with the right hormonal balance, you will think more clearly and feel better than ever." -- Daniel Amen, CEO of Amen Clinics and New York Times bestselling author of The Daniel Plan and Change Your Brain, Change Your Life "Feeling cranky, exhausted, and stressed shouldn't be the norm. With Sara Gottfried's practical advice, you can balance your hormones naturally-without a bunch of pills-and feel at home in your body once again. The Hormone Reset Diet holds the keys to total transformation." -- Cynthia Pasquella, founder and director of the Institute of Transformational Nutrition "Dr. Sara shares her personal journey of regaining her own health while juggling her family's needs and a demanding career. Not only does she show you that rejuvenation is possible, she gives you the insights and the recipes that will make it happen for you." -- Alan Christianson, NMD, author of The Adrenal Reset Diet "Gottfried's chatty, encouraging, woman-to-woman tone makes a very challenging diet plan seem quite doable, as does an appealing layout with boxes, illustrations, and tables. This diet guide seems certain to hit bestseller lists." -- Publishers Weekly

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Book SynopsisA proven 21-day diet and lifestyle plan to help women with polycystic ovary syndrome (PCOS) take back control of their health and resolve their symptoms from a certified health coach and founder of the large PCOS Diva online community.PCOS is one of the most common hormonal disorders, and the most common cause of female infertility, affecting roughly five million American women. Because it’s symptoms are widespread—including stubborn weight gain, acne, mood swings, abnormal hair loss or growth, and irregular menstrual cycles—women suffering from PCOS are often misdiagnosed and treated with Band-Aid pharmaceuticals with uncomfortable side effects that only mask PCOS’s root causes. While there is no cure for PCOS, women can learn to control their symptoms naturally. In this welcome guide, Amy Medling shows how to combine an anti-inflammatory and hormone-balancing diet, daily movement, and stress-reducing self-care to successfully treat their PC

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Book SynopsisNew York Times bestsellerBestselling author Dr. Sara Gottfried shares a new, female-friendly keto diet that addresses women’s unique hormonal needs, so readers can shed pounds and maintain the loss more easily.It’s no surprise that most diet plans don’t work for women—most health studies are based on men instead of women, so women have no choice but to follow plans that were created by and for men. The trouble is: women’s bodies don’t work the same way. Popular programs can actually make it harder for women to lose weight, because they can wreak havoc on a woman’s complex and delicate hormonal system. New York Times bestselling author Dr. Sara Gottfried has spent her career demystifying hormones and helping patients improve their health with personalized medicine. In Women, Food, and Hormones, she presents the Gottfried Protocol, a science-based, road-tested plan designed to reset and balance your hormones and accelerate fat loss. Featuring a female-friendly fasting protocol and ketogenic diet that’s tailor-made for women, the Gottfried Protocol is designed to: Work with, not against, women’s hormones—unlike other keto plans. Improve detoxification and blood sugar levels while decreasing stress, hunger, and cravings.  Target belly fat and reduce inflammation. Increase levels of key anti-aging hormones. Complete with essential troubleshooting tips and more than 50 delicious and filling recipes, Women, Food, and Hormones is your all-in-one-guide to hormonal balance and a healthy new you. 

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Book SynopsisTable of Contents1. History of the identification of gigantism and acromegaly Liliya Rostomyan, Albert Beckers and Patrick Petrossians 2. Pathology of pituitary growth hormone excess Sylvia L. Asa and Shereen Ezzat 3. Gigantism: clinical diagnosis and description, Iulia Potorac Liliya Rostomyan, Adrian F. Daly, Patrick Petrossians and Albert Beckers 4. Acromegaly: clinical description and diagnosis Kevin C.J. Yuen and Albert Becker 5. GPR101, an orphan G-protein coupled receptor, with roles in growth, puberty, and possibly appetite regulation Fady Hannah-Shmouni and Constantine A. Stratakis 6. The role of the aryl hydrocarbon receptor interacting protein in pituitary tumorigenesis Laura C. Herna´ndez-Rami´rez 7. The 3PAs syndrome and succinate dehydrogenase deficiency in pituitary tumors Paraskevi Xekouki, Vasiliki Daraki, Grigoria Betsi, Maria Chrysoulaki, Maria Sfakiotaki, Maria Mytilinaiou and Constantine A. Stratakis 8. CDKN1B (p27) defects leading to pituitary tumors Sebastian Gulde and Natalia S. Pellegata 9. Multiple endocrine neoplasia syndromes and somatotroph adenomas Carolina R.C. Pieterman and Steven G. Waguespack 10. GNAS, McCuneErika Peverelli, Donatella Treppiedi, Federica Mangili Rosa Catalano and Giovanna Mantovani 11. Surgical management of growth hormone-secreting adenomas Elizabeth Hogan and Prashant Chittiboina 12. Medical management of pituitary gigantism and acromegaly Adrian F. Daly and Albert Beckers 13. GHRH-producing tumors and other neuroendocrine neoplasms associated with acromegaly and/or gigantism Sara Pakbaz, Anjelica Hodgson and Ozgur Mete 14. Increased growth hormone secretion from lesions outside the anterior pituitary Christina Tatsi and Constantine A. Stratakis

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Book SynopsisTrade Review"This book is a good refresher for budding endocrinologists in training or even primary care physicians/specialists. I enjoyed reading it. This edition, published 13 years after the previous edition, is more reader-friendly with lots of references and figures. The website lets readers access the book on the go, a need of the hour of medical professionals today." --© Doody’s Review Service, 2021, Deepika Arvind Panday, MD, reviewer, expert opinion "Goodman's Basic Medical Endocrinology, Fifth Edition, has been student tested and approved for decades. This essential textbook provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. It is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study." --Anticancer Research Praise for previous editions: "...provides a solid overview of endocrine function and control...an introductory text that provides a solid basis of background information for the aspiring clinician, or for students planning to progress in a direction that investigates a broader range of organisms." --GENERAL AND COMPARATIVE ENDOCRINOLOGY "...presents the subject of human endocrinology in a way that actually makes the reader want more...this is an outstanding text for medical students, graduate students, and researchers who need a good reference book in the field." --LIFE SCIENCE BOOK REVIEWTable of Contents1. Introduction 2. Pituitary gland 3. Thyroid gland 4. The adrenal glands 5. Principles of hormone integration 6. Hormones of the gastrointestinal tract 7. The pancreatic islets 8. Hormonal regulation of fuel metabolism 9. Regulation of salt and water balance 10. Hormonal regulation of calcium balance 11. Hormonal control of growth 12. Hormonal control of reproduction in the male 13. Hormonal control of reproduction in the female: the menstrual cycle 14. Hormonal control of pregnancy and lactation

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Book SynopsisTable of Contents1. Neurologic complications of pediatric congenital heart disease 2. Neurologic complications of congenital heart disease in adults 3. Neurologic complications of rheumatic fever 4. Neurologic complications of nonrheumatic valvular heart disease 5. Advances and ongoing controversies in PFO closure and cryptogenic stroke 6. Neurological complications of coronary heart disease and their management 7. Neurologic complications of heart surgery 8. Neurological complications of heart failure 9. Neurological complications of cardiomyopathies 10. Neurologic complications of myocarditis 11. Neurologic complications of infective endocarditis 12. Neurologic complications of nonbacterial thrombotic endocarditis 13. Neurologic complications of atrial fibrillation: Pharmacologic and interventional approaches to stroke prevention 14. Tachyarrhythmias and neurologic complications 15. Neurologic complications of brady-arrhythmias 16. Effects of acute neurologic disease on the heart 17. Neurologic complications of genetic channelopathies 18. Neurological complications of syncope and sudden cardiac arrest 19. Neurologic complications of cardiac arrest 20. Neurologic complications of implantable devices 21. Neurologic complications of diseases of the aorta 22. Cerebral aneurysms and cervical artery dissection: Neurological complications and genetic associations 23. Neurological complications of systemic hypertension 24. Neurologic complications of venous thromboembolism 25. Neurologic complications of cardiac disease in athletes 26. Cerebrovascular manifestations of tumors of the heart 27. Stroke in pregnancy 28. Hemodynamics in acute stroke: Cerebral and cardiac complications 29. Neurological complications of cardiovascular drugs 30. The role of biomarkers and neuroimaging in ischemic/hemorrhagic risk assessment for cardiovascular/cerebrovascular disease prevention 31. Clinical utility of echocardiography in secondary ischemic stroke prevention 32. The relationship between heart disease and cognitive impairment 33. Anxiety and psychological management of heart disease and heart surgery

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Book SynopsisTable of ContentsSECTION 1 Introduction 1. Introduction: The anterior hypothalamus 2. History of hypothalamic research: “The spring of primitive existence” 3. Anatomy and cytoarchitectonics of the human hypothalamus 4. Morphology and distribution of hypothalamic peptidergic systems 5. MRI maps, segregation, and white matter connectivity of the human hypothalamus in health 6. Magnetic resonance imaging of the hypothalamo–pituitary region 7. Resting-state functional connectivity of the human hypothalamus 8. Neurogenesis in the adult hypothalamus: A distinct form of structural plasticity involved in metabolic and circadian regulation, with potential relevance for human pathophysiology 9. Matching of the postmortem hypothalamus from patients and controls SECTION 2 The basal forebrain cholinergic system 10. Spatial topography of the basal forebrain cholinergic projections: Organization and vulnerability to degeneration 11. The diagonal band of Broca in health and disease 12. Nucleus basalis of Meynert degeneration predicts cognitive impairment in Parkinson's disease 13. Enlargement of early endosomes and traffic jam in basal forebrain cholinergic neurons in Alzheimer's disease 14. Gene and cell therapy for the nucleus basalis of Meynert with NGF in Alzheimer's disease SECTION 3 The circadian system 15. The circadian system: From clocks to physiology 16. Development of the circadian system and relevance of periodic signals for neonatal development 17. Disrupted circadian rhythms and mental health 18. Diurnal and seasonal molecular rhythms in the human brain and their relation to Alzheimer disease 19. Circadian changes in Alzheimer's disease: Neurobiology, clinical problems, and therapeutic opportunities 20. The circadian system in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy 21. Retina and melanopsin neurons 22. Melatonin and the circadian system: Keys for health with a focus on sleep 23. Melatonin receptors, brain functions, and therapies 24. Chronotherapy 25. The use of melatonin to mitigate the adverse metabolic side effects of antipsychotics SECTION 4 Bed nucleus of the stria terminalis and the fear circuit 26. Chemoarchitecture of the bed nucleus of the stria terminalis: Neurophenotypic diversity and function 27. Functional anatomy of the bed nucleus of the stria terminalis–hypothalamus neural circuitry: Implications for valence surveillance, addiction, feeding, and social behaviors 28. Roles of the bed nucleus of the stria terminalis and amygdala in fear reactions SECTION 5 Preoptic area 29. The median preoptic nucleus: A major regulator of fluid, temperature, sleep, and cardiovascular homeostasis 30. The neuroendocrinology of the preoptic area in menopause: Symptoms and therapeutic strategies 31. The intermediate nucleus in humans: Cytoarchitecture, chemoarchitecture, and relation to sleep, sex, and Alzheimer disease

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Book SynopsisTable of ContentsSection I. Introduction to Mitochondrial Diseases 1. Mitochondrial disease in neurology – Past, present, and future Section II. Most Common Neurological Manifestations of Mitochondrial Disease 2. Progressive external ophthalmoplegia 3. Mitochondrial optic neuropathies 4. Leigh syndrome 5. Stroke-like episodes in adult mitochondrial disease 6. Ataxia and spastic paraplegia in mitochondrial disease 7. Peripheral neuropathy in mitochondrial disease 8. Complex neurological and multisystem presentations in mitochondrial disease Section III. Diagnosing Mitochondrial Disease 9. Investigation of oxidative phosphorylation activity and composition in mitochondrial disease 10. Genetics of mitochondrial diseases: Current approaches for the molecular diagnosis 11. Laboratory and metabolic investigations 12. Neuroimaging in mitochondrial disease Section IV. Therapy and Future Challenges 13. Currently available therapies in mitochondrial disease 14. Reproductive options in mitochondrial disease 15. Clinical trials in mitochondrial disease 16. Blood biomarkers of mitochondrial disease – One for all or all for one? 17. Experimental therapy for mitochondrial diseases

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Book SynopsisTable of ContentsSection I. Introduction 1. The connectional anatomy of the temporal lobe 2. Anatomy of the temporal lobe: From macro to micro Section II. Structure/functions of the T Lobe, as they emerge from studies in healthy participants and brain-damaged populations 3. Music processing and amusia 4. Cortical disorders of speech processing: Pure word deafness and auditory agnosia 5. Neuroplasticity following cochlear implants 6. Components of language processing and their long-term and working memory storage in the brain 7. Cross-modal integration and plasticity in the superior temporal cortex 8. Visual mental imagery: Inside the mind’s eyes 9. The functions of the temporal-parietal junction 10. Visual objects and their colors 11. Face processing in the temporal lobe 12. The neural underpinnings of word comprehension and production: The critical roles of the temporal lobes 13. Domain-specific connectivity drives the organization of object knowledge in the temporal lobe 14. The noun-verb distinction 15. The neural correlates of abstract and concrete words 16. Acquired dyslexias following temporal lesions 17. Proper names and personal identity 18. Neural correlates of recognition and naming of famous persons and landmarks: A special role for the left anterior temporal lobe 19. The temporal lobes and memory 20. Working memory and active sampling of the environment: Medial temporal contributions 21. Amygdala function in emotion, cognition, and behavior 22. Amygdala connectivity and implications for social cognition and disorders Section III. Diseases of/in the temporal lobe 23. Neuropathology of the temporal lobe 24. Frontotemporal dementia: A unique window on the functional role of the temporal lobes 25. The temporal lobe in typical and atypical Alzheimer disease 26. Limbic encephalitis 27. Semiology, EEG, and neuroimaging findings in temporal lobe epilepsies 28. Neuropsychology of temporal lobe epilepsies 29. Surgery procedures in temporal lobe epilepsies

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Book SynopsisTable of ContentsSECTION 3. Neuropalliative Care in Specific Settings 1. Palliative care after stroke survival 2. Palliative care approaches to acute stroke in the hospital setting 3. Outpatient neuropalliative care 4. Community-based neuropalliative care SECTION 4. Neuropalliative Care for Specific Conditions 5. Palliative care in brain tumors 6. Palliative care for people with dementia 7. Palliative care in Parkinson disease and related disorders 8. Palliative care in multiple sclerosis 9. Palliative care principles in ALS 10. Pediatric neuropalliative care 11. Neonatal neuropalliative aare SECTION 5. Psychosocial Support, Ethics and Education 12. Care partner support 13. Spirituality and spiritual distress in neurologic illness 14. Neurology ethics at the end of life 15. Education in neuropalliative care

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Book SynopsisIn light of increasing recognition of thyroid disease as a health problem and increased understanding of the causes of the disorder, the fourth edition of this popular title covers a wide range of conditions associated with thyroid dysfunction and includes new chapters on thyroid disorders in infants, children and adolescents.Trade ReviewNo major areas are ignored, and patients who want more information on these subjects will have a good background after reading this book...I will be suggesting it to my own patients. * Doody's NotesMelissa Porter in the Daily Mail *Table of Contents1. The thyroid gland ; 2. Things that go wrong with the thyroid gland ; 3. How the doctor finds out what is wrong ; 4. Thyroid overactivity caused by Graves' disease ; 5. The eye changes associated with Graves' disease ; 6. Other causes of thyroid overactivity ; 7. Underactivity of the thyroid and its causes in adults ; 8. Hashimoto's thyroiditis ; 9. Subacute viral thyroiditis ; 10. Simple non-toxic goitre ; 11. Multinodular goitre and the solitary nodule ; 12. Cancer of the thyroid gland ; 13. Thyroid problems during and after pregnancy ; 14. Thyroid problems in infants, children and adolescents ; 15. Miscellaneous disorders of the thyroid gland ; 16. Other diseases associated with thyroid disorders ; 17. Who should be tested for thyroid problems? ; 18. Who should be referred to a specialist?

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Book SynopsisHormones are vital to the workings of the body, and while many people are aware of what hormones do, few have an appreciation of the nature and importance of the endocrine system. In this Very Short Introduction, Martin Luck explains what hormones are, what they do, where they come from, and how they work.Trade Reviewan informative and readable overview to the subject * Guardian *Table of Contents1. Hormones, history, and the shoulders of giants ; 2. What and how ; 3. Nuns, catastrophes, and the mysteries of reproduction ; 4. Water, salt, and blood pressure ; 5. The hard stuff: calcium, cells, bones, and cancer ; 6. Appetite, fat, and obesity ; 7. The thyroid gland ; 8. Light and dark ; 9. Changing perspectives ; Further reading ; Index

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Book SynopsisThe sixth edition of this highly popular text retains its comprehensive coverage of endocrine basics from previous editions while featuring entirely new chapters on several topics, including the assessment of endocrine function, sexual differentiation, growth regulation, the thyroid, the adrenals, and calcium homeostasis. Chapters have been updated and reorganized to make information easily accessible in concise form, and new figures and tables have been added to enhance the presentation of complex concepts. Fundamental principles of endocrine physiology are reinforced with illustrative examples from clinical observation and the limitations of current knowledge are properly identified. The ideal resource for students entering the field, the Textbook of Endocrine Physiology aims to provide for all a solid basis in fundamentals of endocrinology and for some, inspiration for the pursuit of advanced medical or graduate studies in the field.Trade ReviewReview(s) from previous edition(s)provides a succinct account of basic endocrine function * Baslib Book List *The second and third chapters "Genes and Hormones" and "Mechanisms of Hormone Action" are clear and useful guides to understanding the molecular and biochemical bases of hormonal action ... valuable for the medical student. * General and Comparative Endocrinology 91 *the expertise of the contributors in their fields is evident throughout; and the approach and level of detail are appropriate in the UK for second-year preclinical students, for those studying endocrine options and for those in clinical years needing to refresh and apply their knowledge of physiology. * BM. A. Radcliffe, Experimental Physiology *Excellent introductory text. * Joseph Jarabak, University of Chicago *It is a must read for graduate students and fellows. * Doris Baktuska, M.D., Medical College of Pennsylvania *Excellent text. I would recommend it as required reading for all medical students. * Romesh Khardori, M.D., Southern Illinois University School of Medicine *Well written by the best experts in the field. * Michael D. Lumpkin, PhD, Georgetown University Medical School *This text succeeds in providing excellent, very readable coverage of the field of endocrinology. The clearness of writing is commendable. This text can be highly recommended for graduate level courses and for medical students beyond the first year. * Endocrine News *In summary, this textbook incorporates modern concepts inan excellent, readable, concise, and comprehensive introduction or review of endocrine physiology. * Annals of the Royal College of Physicians and Surgeons of Canada *The coverage, readability, currency, and cost make Griffin and Ojeda's newest edition a best buy for classroom use or overall review purposes. * Item *It remains a solid text book of endocrinology written in a clear, no-nonsense style. * Physiology News, No 58 *Table of ContentsContributors ; 1. Organization of the Endocrine System ; 2. Genes and Hormones ; 3. Mechanisms of Hormone Action ; 4. Assessment of Endocrine Function ; 5. The Anterior Pituitary and Hypothalamus ; 6. The Posterior Pituitary and Water Metabolism ; 7. Sexual Differentiation ; 8. Female Reproductive Function ; 9. Male Reproductive Function ; 10. Fertilization, Implantation, and Endocrinology of Pregnancy ; 11. Growth Regulation ; 12. The Thyroid ; 13. The Adrenal Glands ; 14. Calcium Homeostasis ; 15. Glucose, Lipid, and Protein Metabolism ; Index

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Book SynopsisHannah Alderson's mission is to educate, empower and create a positive force in women's lives - providing them with the knowledge to navigate hormonal health and happiness via nutrition, sleep, movement, self love, positive mindset and creativity. Through her clinic, The Positive Method, Hannah works with women to balance hormones and boost happiness. Her clinical specialisms are PCOS, fertility, perimenopause, menopause, fat loss and endometriosis.She is a BANT Registered Nutritionist and Functional Medicine Practitioner, member of The British Menopause Society, member of the Institute of Functional Medicine and sits on the Medical Advisory board for the PCOSAA (The American Charity, Polycystic Ovarian Syndrome Awareness Association). She is highly motivated to promote the book and is the go-to expert for glossy lifestyle magazines worldwide.

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Book SynopsisThe all-in-one, comprehensive resource for the millions of people with diabetes who use insulin, revised and updatedFew diabetes books focus specifically on the day-to-day issues facing people who use insulin. Gary Scheiner provides the tools to think like a pancreas -- to successfully master the art and science of matching insulin to the body''s ever-changing needs. Comprehensive, free of medical jargon, and packed with useful information not readily available elsewhere, such as:- day-to-day blood glucose monitoring and management- designing an insulin program to best match your needs and lifestyle- how to get the best results from CGM and automated insulin delivery systems- new insulin formulations and combinations- detailed strategies for meeting your personal goals- what drugs like Trulicity, Ozempic and Mounjaro mean for you and your health- and much moreWhether you take insulin once a day or take multiple daily injections, use a stand-alone pump or an automated insulin delivery system, Think Like a Pancreas is your go-to guide!

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Book SynopsisIf you are one of the 20 million Americans living with thyroid disease or one of the thousands living undiagnosed, Dr. Raphael Kellman understands your suffering. Between inaccurate diagnosis, a wide spectrum of symptoms, and doctors who may not be familiar with the intricacies of thyroid dysfunction, it''s hard to get the treatment you need. While general hypothyroidism and Hashimoto''s thyroiditis are the most commonly known thyroid issues, there is an underdiagnosed and yet incredibly prevalent condition: Non-thyroidal Illness Syndrome (NTIS). It can cause unexplained fatigue, memory issues, problems with focus and decision making, and even dementia, and affects as many as 20% of Hashimoto''s sufferers. Luckily, Dr. Kellman has a clinically proven, expert protocol that has given thousands of patients a path to health-and now he''s delivering it to you. You''ll discover: How your thyroid function affects your overall health-and how its dysfunction can explain your tro

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Book SynopsisTable of ContentsCHAPTER 1 INTRODUCTION TO THE ENDOCRINE SYSTEM Objectives Chemical Nature of Hormones Transport of Hormones in the Circulation Cellular Responses to Hormones Summary Self-study Problems Keywords and Concepts CHAPTER 2 ENDOCRINE FUNCTION OF THE GASTROINTESTINAL TRACT 27 Objectives Enteroendocrine Hormone Families and Their Receptors Gastrin and the Regulation of Gastric Function Enteroendocrine Regulation of the Exocrine Pancreas and Gallbladder Insulinotropic Actions of Gastrointestinal Peptides (Incretin Action) Enterotropic Actions of Gastrointestinal Hormones Summary Self-study Problems Keywords and Concepts CHAPTER 3 ENERGY METABOLISM Key Pathways Involved in Energy Metabolism Objectives Overview of Energy Metabolism General Pathways Involved in Energy Metabolism Key Hormones Involved in Metabolic Homeostasis Metabolic Homeostasis: The Integrated Outcome of Hormonal and Substrate/Product Regulation of Metabolic Pathways Liver Skeletal Muscle Adipose Tissue-Derived Hormones and Adipokines Appetite Control and Obesity Diabetes Mellitus Summary Self-study Problems Keywords and Concepts CHAPTER 4 CALCIUM AND PHOSPHATE HOMEOSTASIS Objectives Calcium and Phosphorus are Important Dietary Elements that Play Many Crucial Roles in Cellular Physiology Physiologic Regulation of Calcium and Phosphate: Parathyroid Hormone and 1,25-Dihydroxyvitamin D Small Intestine, Bone, and Kidney Determine Ca2þ and Pi Levels Pathologic Disorders of Calcium and Phosphate Balance Summary Self-study Problems Keywords and Concepts CHAPTER 5 HYPOTHALAMUS-PITUITARY COMPLEX. Objectives Embryology and Anatomy Neurohypophysis Adenohypophysis Summary Self-study Problems Keywords and Concepts CHAPTER 6 THE THYROID GLAND Objectives Anatomy and Histology of the Thyroid Gland Production of Thyroid Hormones Transport and Metabolism of Thyroid Hormones Summary Self-study Problems Keywords and Concepts CHAPTER 7 THE ADRENAL GLAND Objectives Anatomy Adrenal Medulla Adrenal Cortex Zona Glomerulosa Pathologic Conditions Involving the Adrenal Cortex Summary Self-study Problems Keywords and Concepts 176.e1 CHAPTER 8 LIFE CYCLE OF THE MALE AND FEMALE REPRODUCTIVE SYSTEMS Objectives General Components of a Reproductive System Overview of Meiosis Basic Anatomy of the Reproductive Systems Sexual Development in Utero Puberty Menopause and Andropause Summary Self-study Problems Keywords and Concepts 193.e1 CHAPTER 9 THE MALE REPRODUCTIVE SYSTEM Objectives Histophysiology of the Testis Transport, Actions, and Metabolism of Androgens Hypothalamus-Pituitary-Testis Axis Male Reproductive Tract Disorders Involving the Male Reproductive System Summary Self-study Problems Keywords and Concepts 213.e1 CHAPTER 10 THE FEMALE REPRODUCTIVE SYSTEM Objectives Anatomy and Histology of the Ovary Growth, Development, and Function of the Ovarian Follicle The Human Menstrual Cycle Female Reproductive Tract Biology of Estradiol and Progesterone Ovarian Pathophysiology Summary Self-study Problems Keywords and Concepts 238.e1 CHAPTER 11 FERTILIZATION, PREGNANCY, AND LACTATION Objectives Fertilization, Early Embryogenesis, Implantation, and Placentation Placental Transport The Fetal Endocrine System Maternal Endocrine Changes During Pregnancy Maternal Physiologic Changes During Pregnancy Parturition Mammogenesis and Lactation Contraception In Vitro Fertilization Summary Self-study Problems Keywords and Concepts APPENDIX A: ANSWERS TO SELF-STUDY PROBLEMS . APPENDIX B: COMPREHENSIVE MULTIPLE-CHOICE EXAMINATION APPENDIX C: HORMONE RANGES APPENDIX D: ABBREVIATIONS AND SYMBOLS INDEX

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Book SynopsisTable of ContentsContents Top Secrets 1 I Fuel Metabolism CHAPTER 1 Diabetes Mellitus: Etiology, Classification, and Diagnosis Adnin Zaman and Cecilia C. Low Wang CHAPTER 2 Diabetes Mellitus: Acute and Chronic Complications Cecilia C. Low Wang and Adnin Zaman CHAPTER 3 Type 1 Diabetes Mellitus Jennifer M.Trujillo CHAPTER 4 Type 2 Diabetes Mellitus Sarah L. Anderson and Jennifer M. Trujillo CHAPTER 5 Diabetes Technology: Pumps, Sensors, and Beyond Adnin Zaman and Cecilia C. Low Wang CHAPTER 6 Carbohydrate Counting-Guided Insulin Dosing: Practice Exercises Michael T. McDermott CHAPTER 7 Inpatient Management of Diabetes and Hyperglycemia Stacey A. Seggelke and R. Matthew Hawkins CHAPTER 8 Diabetes in Pregnancy Amy M. Valent and Linda A. Barbour CHAPTER 9 HYPOGLY CEMIC DISORDERS Helen M. Lawler CHAPTER 10 Lipid Disorders Emily B. Schroeder and Michael McDermott CHAPTER 11 Obesity Elizabeth A. Thomas and David Saxon II B one and Mineral Disorders CHAPTER 12 Osteoporosis and Other Metabolic Bone Diseases: Evaluation Michael T. McDermott CHAPTER 13 Measurement of Bone Mass Christine Swanson CHAPTER 14 Osteoporosis Management Michael T. McDermott CHAPTER 15 Osteomalacia, Rickets, and Vitamin D Insufficiency William E. Duncan CHAPTER 16 Paget's Disease of Bone Matthew P. Wahl and Christine M. Swanson CHAPTER 17 Hypercalcemia Leonard R. Sanders CHAPTER 18 Hyperparathyroidism Leonard R. Sanders CHAPTER 19 Hypercalcemia of Malignancy Michael T. McDermott CHAPTER 20 Hypocalcemia Shari C. Fox CHAPTER 21 Nephrolithiasis Leonard R. Sanders III P ituitary and Hypothalamic Disorders CHAPTER 22 Pituitary Insufficiency John J. Orrego CHAPTER 23 Nonfunctioning Pituitary Tumors and Pituitary Incidentalomas Janice M. Kerr and Michael T. McDermott CHAPTER 24 Pituitary Stalk Lesions Janice M. Kerr CHAPTER 25 Prolactin-Secreting Pituitary Tumors Virginia Sarapura CHAPTER 26 Growth Hormone-Secreting Pituitary Tumors Mary H. Samuels CHAPTER 27 Cushing's Syndrome Mary H. Samuels CHAPTER 28 Glycoprotein-Secreting Pituitary Tumors Majlinda Xhikola, Shon Meek, and Robert C. Smallridge CHAPTER 29 Water Metabolism Leonard R. Sanders CHAPTER 30 Disorders of Growth Philip Zeitler CHAPTER 31 Growth Hormone Use and Abuse Carlos A. Torres and Homer J. LeMar, Jr. IV A drenal Disorders CHAPTER 32 Primary Aldosteronism John J. Orrego CHAPTER 33 Pheochromocytomas and Paragangliomas John J. Orrego CHAPTER 34 Adrenal Incidentalomas Michael T. McDermott CHAPTER 35 Adrenal Malignancies Michael T. McDermott CHAPTER 36 Adrenal Insufficiency Emily B. Schroeder and Cecilia C. Low Wang CHAPTER 37 Congenital Adrenal Hyperplasia Harris M. Baloch, Nicole Vietor, and Robert A. Vigersky V Thyroid Disorders CHAPTER 38 Thyroid Testing Michael T. McDermott CHAPTER 39 Hyperthyroidism Thanh D. Hoang and Henry B. Burch CHAPTER 40 Hypothyroidism Katherine Weber and Bryan R. Haugen CHAPTER 41 Thyroiditis Ayesha F. Malik, Robert C. Smallridge, and Ana Chindris CHAPTER 42 Thyroid Nodules and Goiter Michele B. Glodowski and Sarah E. Mayson CHAPTER 43 THYROID CANCER Veena R. Agrawal and Sarah E. Mayson CHAPTER 44 Thyroid Emergencies Michael T. McDermott CHAPTER 45 Euthyroid Sick Syndrome Michael T. McDermott CHAPTER 46 Thyroid Disease in Pregnancy Meghan Donnelly and Linda Barbour CHAPTER 47 Psychiatric Disorders and Thyroid Disease Roselyn I. Mateo and James V. Hennessey VI R eproductive Endocrinology CHAPTER 48 Differences (Disorders) of Sexual Differentiation Richard O. Roberts, III and Robert H. Slover CHAPTER 49 Disorders of Puberty Shanlee M. Davis and Sharon H. Travers CHAPTER 50 Male Hypogonadism Katherine N. Vu, Vinh Q. Mai, and Robert A. Vigersky CHAPTER 51 Erectile Dysfunction Mark M. Cruz, Thanh D. Hoang, and Robert A. Vigersky CHAPTER 52 Gynecomastia Mark Bridenstine, Brenda K. Bell, and Micol S. Rothman CHAPTER 53 Amenorrhea Micol S. Rothman and Margaret E. Wierman CHAPTER 54 Polycystic Ovarian Syndrome Melanie Cree-Green and Anne-Marie Carreau CHAPTER 55 Hirsutism and Virilization Tamis M. Bright and Aziz Ur Rehman CHAPTER 56 Menopause Wesley Nuffer CHAPTER 57 G ender-Affirming Treatment for Adults with Gender Incongruence and Gender Dysphoria Micol S. Rothman and Sean J. Iwamoto CHAPTER 58 U se and Abuse of Anabolic-Androgenic Steroids and Androgen Precursors Carlos A. Torres and Homer J. LeMar VII Miscellaneous Topics CHAPTER 59 Autoimmune Polyglandular Syndromes Richard Millstein CHAPTER 60 Multiple Endocrine Neoplasia Syndromes John J. Orrego CHAPTER 61 Pancreatic Neuroendocrine Tumors Michael T. McDermott CHAPTER 62 Carcinoid Syndrome Michael T. McDermott CHAPTER 63 Aging and Endocrinology Kerrie L. Moreau, Sean J. Iwamoto, and Shauna Runchey CHAPTER 64 Endocrinopathies Caused by Immune Checkpoint Inhibitors David Saxon and Thomas Jensen CHAPTER 65 Sleep and Endocrinology Roger A. Piepenbrink CHAPTER 66 Thyroid and Parathyroid Surgery Logan R. McKenna, Maria B. Albuja-Cruz, Robert C. McIntyre Jr., and Christopher D. Raeburn CHAPTER 67 Adrenal Surgery Oliver J. Fackelmayer, Chris Raeburn, Robert McIntyre Jr., and Maria Albuja-Cruz CHAPTER 68 Pancreas and Other Endocrine Tumor Surgery Stephanie Davis, Maria Albuja-Cruz, Chris Raeburn, and Robert McIntyre, Jr. CHAPTER 69 Bariatric Surgery Jonathan A. Schoen and Kevin B. Rothchild CHAPTER 70 Endocrinology in Africa Helen Yifter Bitew and Abdurezak Ahmed Abdela CHAPTER 71 Famous People With Endocrine Disorders Pratima Kumar, Kenneth J. Simcic, and Michael T. McDermott CHAPTER 72 Interesting Endocrine Facts and Figures Michael T. McDermott CHAPTER 73 Endocrine Case Studies Michael T. McDermott Index

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Book SynopsisTable of ContentsSECTION I Principles and Methods of Pediatric Endocrinology, 1 1. Overview and Principles of Pediatric Endocrinology, 1 Mark A. Sperling 2. Molecular Endocrinology, Endocrine Genetics, and Precision Medicine, 9 Ram K. Menon, Massimo Trucco, Joseph A. Majzoub, Constantine A. Stratakis 3. Receptor Transduction Pathways Mediating Hormone Action, 30 Bassil Kublaoui, Michael A. Levine 4. Endocrinology Laboratory Testing, 86 Jon Nakamoto SECTION II Endocrine Disorders in the Neonate, 106 5. Fetal-Maternal Endocrinology and Parturition, 106 Sam Mesiano, Helen N. Jones, Heide Aungst, Tani Malhotra, Louis J. Muglia 6. Ambiguous Genitalia, 123 Selma Feldman Witchel, Peter A. Lee 7. Hypoglycemia in the Newborn and Infant, 175 Diva D. De Leon, Paul Thornton, Charles A. Stanley, Mark A. Sperling 8. Disorders of the Thyroid in the Newborn and Infant, 202 Johnny Deladoey, Julia Elisabeth von Oettingen, Guy Van Vliet 9. Disorders of Mineral Metabolism: Normal Homeostasis, 220 Allen W. Root 10. Monogenic Diabetes Mellitus: Neonatal Diabetes and Maturity-Onset Diabetes of the Young, 279 Siri Atma W. Greeley*, Mary K. McCauley*, Louis H. Philipson, Mark A. Sperling *Authors contributed equally to this chapter SECTION III Childhood and Adolescent Endocrinology, 299 11. Disorders of Childhood Growth, 299 Alexander A.L. Jorge, Adda Grimberg, Mehul T. Dattani, Jeffrey Baron 12. Disorders of the Posterior Pituitary, 357 Abhinash Srivatsa, Joseph A. Majzoub 13. Thyroid Disorders in Children and Adolescents, 395 Scott Rivkees, Andrew J. Bauer 14. The Adrenal Cortex and Its Disorders, 425 Walter L. Miller, Christa E. Flück, David T. Breault, Brian J. Feldman 15. Pheochromocytoma/Paraganglioma, Medullary Thyroid Carcinoma, and Hereditary Endocrine Neoplasia Syndromes, 491 Steven G. Waguespack, Lauren Fishbein 16. Puberty in the Female and Its Disorders, 528 Robert L. Rosenfield, David W. Cooke, Sally Radovick 17. Turner Syndrome, 627 Philippe Backeljauw, Steven D. Chernausek, Claus Højbjerg Gravholt, Paul Kruszka 18. Puberty and Its Disorders in the Male, 661 Mark R. Palmert, Yee-Ming Chan, Leo Dunkel 19. Care of Transgender/Gender Nonconforming Youth, 695 Stephen M. Rosenthal, Amy B. Wisniewski 20. Disorders of Mineral Metabolism II. Abnormalities of Mineral Homeostasis in the Newborn, Infant, Child, and Adolescent, 705 Allen W. Root, Michael A. Levine 21. Diabetes Mellitus, 814 Mark A. Sperling, Joseph I. Wolfsdorf, Ram K. Menon, William V. Tamborlane, David Maahs, Tadej Battelino, Moshe Phillip 22. Autoimmune Polyglandular Syndromes, 884 Bimota Nambam, Michael J. Haller, William E. Winter, Desmond Schatz 23. Hypoglycemia in the Toddler and Child, 904 Joseph I. Wolfsdorf, Charles A. Stanley 24. Obesity, Metabolic Syndrome and Disorders of Energy Balance, 939 Joan C. Han, Ram Weiss 25. Lipid Disorders in Children and Adolescents, 1004 Stephen R. Daniels, Sarah C. Couch Index, 1022 Interactive questions for self-assessment can be found in the e-book; see inside front cover for details.

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Book Synopsis

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Book SynopsisTable of ContentsSECTION 1: THYROID NONNEOPLASTIC HEREDITARY/GENETIC/CONGENITAL 4 Thyroglossal Duct Cyst Vania Nosé, MD, PhD and Nicole A. Cipriani, MD 8 Ectopic Thyroid Vania Nosé, MD, PhD 12 Solid Cell Nests Vania Nosé, MD, PhD 16 Dyshormonogenetic Goiter Vania Nosé, MD, PhD INFECTIOUS 22 Acute Thyroiditis Vania Nosé, MD, PhD AUTOIMMUNE/INFLAMMATORY 26 Subacute/Granulomatous Thyroiditis Vania Nosé, MD, PhD 32 Palpation Thyroiditis Vania Nosé, MD, PhD and Nicole A. Cipriani, MD 34 IgG4-Related Thyroid Disease Vania Nosé, MD, PhD 38 Riedel Thyroiditis Vania Nosé, MD, PhD 44 Hashimoto Thyroiditis Vania Nosé, MD, PhD 52 Graves Disease (Diffuse Hyperplasia) Suzana Leite, MD and Vania Nosé, MD, PhD 60 Amyloid Goiter Vania Nosé, MD, PhD REACTIVE 66 Pigments and Crystals, Thyroid Nicole A. Cipriani, MD and Vania Nosé, MD, PhD 72 Post-FNA Site Changes, Thyroid Vania Nosé, MD, PhD and Darcy A. Kerr, MD NEOPLASTIC FOLLICULAR CELL-DERIVED NEOPLASMS 74 Thyroid Follicular Nodular Disease Vania Nosé, MD, PhD 80 Adenomatous Nodules Vania Nosé, MD, PhD and Lori A. Erickson, MD 86 Follicular Thyroid Adenoma Vania Nosé, MD, PhD and Lori A. Erickson, MD 94 Follicular Thyroid Adenoma With Papillary Architecture Vania Nosé, MD, PhD 98 Oncocytic Thyroid Adenoma Vania Nosé, MD, PhD and Lori A. Erickson, MD 102 Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features Vania Nosé, MD, PhD and Ying-Hsia Chu, MD 112 Hyalinizing Trabecular Tumor of Thyroid Vania Nosé, MD, PhD and Nicole A. Cipriani, MD 118 Follicular Thyroid Carcinoma Vania Nosé, MD, PhD and Lori A. Erickson, MD 128 Oncocytic Thyroid Carcinoma Ying-Hsia Chu, MD and Vania Nosé, MD, PhD 132 Invasive Encapsulated Follicular Variant Papillary Thyroid Carcinoma Vania Nosé, MD, PhD and Lori A. Erickson, MD 140 Kinase Fusion-Related Thyroid Carcinomas Ying-Hsia Chu, MD and Vania Nosé, MD, PhD 148 Follicular Cell-Derived Thyroid Carcinoma, High Grade Nicole A. Cipriani, MD and Vania Nosé, MD, PhD 158 Anaplastic Thyroid Carcinoma Vania Nosé, MD, PhD and Lori A. Erickson, MD 168 Papillary Thyroid Carcinoma Vania Nosé, MD, PhD and Ying-Hsia Chu, MD 182 Classic Papillary Thyroid Carcinoma Vania Nosé, MD, PhD and Julie Guilmette, MD, FRCPC 190 Infiltrative Follicular Variant Papillary Thyroid Carcinoma Vania Nosé, MD, PhD and Lori A. Erickson, MD 194 Macrofollicular Papillary Thyroid Carcinoma Vania Nosé, MD, PhD 200 Diffuse Sclerosing Papillary Thyroid Carcinoma Nicole A. Cipriani, MD and Vania Nosé, MD, PhD 206 Oncocytic Papillary Thyroid Carcinoma Vania Nosé, MD, PhD and Peter M. Sadow, MD, PhD 210 Tall Cell Papillary Thyroid Carcinoma Vania Nosé, MD, PhD and Julie Guilmette, MD, FRCPC 218 Columnar Cell Papillary Thyroid Carcinoma Vania Nosé, MD, PhD and Lori A. Erickson, MD 222 Clear Cell Papillary Thyroid Carcinoma Vania Nosé, MD, PhD and Julie Guilmette, MD, FRCPC 224 Solid/Trabecular Papillary Thyroid Carcinoma Vania Nosé, MD, PhD and Julie Guilmette, MD, FRCPC 228 Hobnail Papillary Thyroid Carcinoma Julie Guilmette, MD, FRCPC and Vania Nosé, MD, PhD 234 Warthin-Like Papillary Thyroid Carcinoma Vania Nosé, MD, PhD C-CELL-DERIVED TUMORS 240 C-Cell Hyperplasia Vania Nosé, MD, PhD and Adam S. Fisch, MD, PhD 246 Medullary Thyroid Carcinoma Vania Nosé, MD, PhD and Adam S. Fisch, MD, PhD MIXED MEDULLARY AND FOLLICULAR CELL CARCINOMA 256 Mixed Medullary and Follicular Cell-Derived Thyroid Carcinoma Vania Nosé, MD, PhD and Darcy A. Kerr, MD THYMIC TUMORS WITHIN THYROID 260 Spindle Epithelial Tumor With Thymus-Like Differentiation Vania Nosé, MD, PhD 266 Intrathyroid Thymic Carcinoma Vania Nosé, MD, PhD SALIVARY GLAND-LIKE THYROID TUMORS 274 Mucoepidermoid Carcinoma of Thyroid Darcy A. Kerr, MD and Vania Nosé, MD, PhD 278 Secretory Carcinoma of Salivary Gland Type Darcy A. Kerr, MD and Vania Nosé, MD, PhD HEMATOLYMPHOID TUMORS 282 Lymphoma, Thyroid Judith Ferry, MD 288 Follicular Dendritic Cell Sarcoma, Thyroid Vania Nosé, MD, PhD and Darcy A. Kerr, MD 292 Langerhans Cell Histiocytosis, Thyroid Vania Nosé, MD, PhD and Dipti P. Sajed, MD, PhD GERM CELL ORIGIN 296 Benign Thyroid Teratoma Vania Nosé, MD, PhD 302 Struma Ovarii, Struma Carcinoid, and Malignant Struma Ovarii Vania Nosé, MD, PhD EMBRYONAL THYROID TUMORS 310 Thyroblastoma Vania Nosé, MD, PhD and Julie Guilmette, MD, FRCPC MESENCHYMAL AND STROMAL TUMORS 316 Peripheral Nerve Sheath Tumor, Thyroid Vania Nosé, MD, PhD and Darcy A. Kerr, MD 320 Solitary Fibrous Tumor, Thyroid Dipti P. Sajed, MD, PhD and Vania Nosé, MD, PhD 326 Paraganglioma, Thyroid Lori A. Erickson, MD and Vania Nosé, MD, PhD 332 Leiomyoma and Leiomyosarcoma, Thyroid Dipti P. Sajed, MD, PhD and Vania Nosé, MD, PhD 336 Angiosarcoma, Thyroid Dipti P. Sajed, MD, PhD and Vania Nosé, MD, PhD 340 Primary Ewing Sarcoma, Thyroid Dipti P. Sajed, MD, PhD and Vania Nosé, MD, PhD SECONDARY TUMORS WITHIN THYROID 344 Metastasis to Thyroid Gland Vania Nosé, MD, PhD and Darcy A. Kerr, MD TUMORS OF UNCERTAIN HISTOGENESIS 350 Cribriform Morular Thyroid Carcinoma Vania Nosé, MD, PhD 360 Sclerosing Mucoepidermoid Carcinoma With Eosinophilia Darcy A. Kerr, MD and Vania Nosé, MD, PhD MOLECULAR PATHOLOGY OF THYROID NEOPLASMS 366 Molecular Pathology of Thyroid Neoplasms Vania Nosé, MD, PhD and Ying-Hsia Chu, MD PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF THYROID GLAND 372 Thyroid Carcinoma Protocol Vania Nosé, MD, PhD and Julie Guilmette, MD, FRCPC SECTION 2: PARATHYROID GLAND NONNEOPLASTIC 376 Primary Multiglandular Parathyroid Disease Lori A. Erickson, MD 386 Primary Parathyroid Clear Cell Hyperplasia Lori A. Erickson, MD 390 Secondary Parathyroid Hyperplasia Lori A. Erickson, MD 396 Tertiary Parathyroid Hyperplasia Lori A. Erickson, MD 400 Chronic Parathyroiditis Lori A. Erickson, MD NEOPLASTIC 404 Parathyroid Adenoma Lori A. Erickson, MD and Vania Nosé, MD, PhD 412 Parathyroid Lipoadenoma Lori A. Erickson, MD 416 Atypical Parathyroid Tumor Vania Nosé, MD, PhD and Lori A. Erickson, MD 422 Parathyroid Carcinoma Vania Nosé, MD, PhD and Lori A. Erickson, MD 432 Metastasis to Parathyroid Gland Lori A. Erickson, MD SECTION 3: ADRENAL GLANDS ADRENAL CORTICAL NONNEOPLASTIC 438 Adrenal Heterotopia Arthur S. Tischler, MD 440 Adrenal Hypoplasia and Malformations Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD 444 Adrenal Cytomegaly Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD 446 Infectious Disorders, Adrenal Glands Arthur S. Tischler, MD and Nada A. Farhat, MD, MA, MPH 450 Autoimmune Adrenalitis Arthur S. Tischler, MD and Nada A. Farhat, MD, MA, MPH 452 Adrenal Amyloidosis Arthur S. Tischler, MD and Nada A. Farhat, MD, MA, MPH 456 Incidental Adrenal Nodules Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD 460 Adrenal Cysts Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD ADRENAL CORTICAL NEOPLASTIC 466 Adrenocortical Hyperplasia and Adrenocortical Nodular Disease Nada A. Farhat, MD, MA, MPH and Arthur S. Tischler, MD 472 Primary Pigmented Nodular Adrenocortical Disease Vania Nosé, MD, PhD 478 Nonfunctioning Adrenal Cortical Adenoma Vania Nosé, MD, PhD and Peter M. Sadow, MD, PhD 480 Aldosterone-Producing Adenoma Vania Nosé, MD, PhD and Patricia Nogueira de Sa, MD 486 Cortisol-Secreting Adrenal Cortical Adenoma Vania Nosé, MD, PhD and Peter M. Sadow, MD, PhD 492 Sex Hormone-Producing Adrenal Cortical Adenoma Vania Nosé, MD, PhD and Peter M. Sadow, MD, PhD 494 Oncocytic Adrenal Cortical Adenoma Vania Nosé, MD, PhD and Peter M. Sadow, MD, PhD 498 Adrenal Cortical Carcinoma Vania Nosé, MD, PhD and Ying-Hsia Chu, MD 510 Adrenal Cortical Neoplasms in Children Vania Nosé, MD, PhD ADRENAL MEDULLA AND PARAGANGLIA 518 Adrenal Medullary Hyperplasia Vania Nosé, MD, PhD 522 Pheochromocytoma and Paraganglioma Vania Nosé, MD, PhD, Arthur S. Tischler, MD, and Ying-Hsia Chu, MD 534 Composite Pheochromocytoma and Composite Paraganglioma Vania Nosé, MD, PhD and Arthur S. Tischler, MD 540 Neuroblastic Tumors of Adrenal Gland Vania Nosé, MD, PhD ADRENAL MESENCHYMAL AND STROMAL TUMORS 552 Primary Adrenal Myelolipoma Vania Nosé, MD, PhD 556 Primary Adrenal Melanoma Vania Nosé, MD, PhD 560 Primary Adrenal Benign Connective Tissue Tumor Vania Nosé, MD, PhD 562 Primary Adrenal Angiosarcoma Vania Nosé, MD, PhD 566 Primary Adrenal Leiomyosarcoma Vania Nosé, MD, PhD 570 Metastasis to Adrenal Gland Vania Nosé, MD, PhD PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF ADRENAL GLAND 574 Adrenal Cortical Carcinoma Protocol Vania Nosé, MD, PhD SECTION 4: PITUITARY GLAND NONNEOPLASTIC 578 Hypophysitis, Pituitary Gland M.Beatriz S. Lopes, MD, PhD 582 Hyperplasia, Pituitary Gland M.Beatriz S. Lopes, MD, PhD 584 Sarcoidosis, Pituitary Gland M.Beatriz S. Lopes, MD, PhD and Vania Nosé, MD, PhD 588 Infarction, Pituitary Gland M.Beatriz S. Lopes, MD, PhD 590 Sheehan Syndrome, Pituitary Gland M.Beatriz S. Lopes, MD, PhD 592 Cystic Lesions of Sellar Region M.Beatriz S. Lopes, MD, PhD 596 Empty Sella Syndrome M.Beatriz S. Lopes, MD, PhD NEOPLASTIC ANTERIOR NEUROENDOCRINE NEOPLASMS 598 Pituitary Neuroendocrine Tumor/Adenoma M.Beatriz S. Lopes, MD, PhD and Vania Nosé, MD, PhD 604 Somatotroph PitNET/Adenoma M.Beatriz S. Lopes, MD, PhD 608 Lactotroph PitNET/Adenoma M.Beatriz S. Lopes, MD, PhD 612 Thyrotroph PitNET/Adenoma M.Beatriz S. Lopes, MD, PhD 616 Plurihormonal PitNET/Adenoma M.Beatriz S. Lopes, MD, PhD 620 Corticotroph PitNET/Adenoma M.Beatriz S. Lopes, MD, PhD 624 Gonadotroph PitNET/Adenoma M.Beatriz S. Lopes, MD, PhD 628 Null Cell PitNET/Adenoma M.Beatriz S. Lopes, MD, PhD 630 Metastatic Pituitary Neuroendocrine Tumor Vania Nosé, MD, PhD and M. Beatriz S. Lopes, MD, PhD OTHER ANTERIOR PITUITARY TUMORS 634 Adamantinomatous Craniopharyngioma M.Beatriz S. Lopes, MD, PhD 636 Papillary Craniopharyngioma M.Beatriz S. Lopes, MD, PhD 638 Pituitary Blastoma POSTERIOR PITUITARY NEOPLASMS 642 Pituicytoma, Spindle Cell Oncocytoma, and Granular Cell Tumor of Sella M.Beatriz S. Lopes, MD, PhD NEURONAL TUMORS 646 Gangliocytoma M.Beatriz S. Lopes, MD, PhD 650 Neuronal Cell Tumors, Pituitary M.Beatriz S. Lopes, MD, PhD OTHER PITUITARY TUMORS 652 Metastasis to Pituitary Gland M.Beatriz S. Lopes, MD, PhD 654 Mesenchymal and Hematopoietic Tumors, Pituitary Gland M.Beatriz S. Lopes, MD, PhD PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH PRIMARY PITUITARY TUMORS 658 Protocol for Examination of Specimens From Patients With Primary Pituitary Tumors Vania Nosé, MD, PhD and M. Beatriz S. Lopes, MD, PhD SECTION 5: ENDOCRINE PANCREAS 664 Pancreatic Neuroendocrine Neoplasms Vania Nosé, MD, PhD PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF ENDOCRINE PANCREAS 674 Pancreatic Neuroendocrine Carcinoma Protocol Vania Nosé, MD, PhD SECTION 6: ENDOCRINE SKIN 678 Merkel Cell Carcinoma Lori A. Erickson, MD SECTION 7: FAMILIAL TUMORSYNDROMES MAJOR ENDOCRINE GLAND AFFECTED THYROID GLAND 690 DICER1 Syndrome Vania Nosé, MD, PhD and Michelle Menon Miyake, MD 700 Familial Thyroid Carcinoma Vania Nosé, MD, PhD 706 McCune-Albright Syndrome Vania Nosé, MD, PhD 712 Multiple Endocrine Neoplasia Type 2 (MEN2) Vania Nosé, MD, PhD 720 Nonsyndromic Familial Follicular Cell-Derived Thyroid Carcinoma Vania Nosé, MD, PhD 726 PTEN Hamartoma Tumor Syndromes Vania Nosé, MD, PhD 734 Syndromic Familial Follicular Cell-Derived Thyroid Carcinoma Vania Nosé, MD, PhD PARATHYROID GLAND 742 Familial Isolated Hyperparathyroidism Vania Nosé, MD, PhD and Lori A. Erickson, MD 746 Hyperparathyroidism-Jaw Tumor Syndrome Vania Nosé, MD, PhD and Lori A. Erickson, MD 754 Multiple Endocrine Neoplasia Type 1 (MEN1) Vania Nosé, MD, PhD and Michelle Menon Miyake, MD 762 Multiple Endocrine Neoplasia Type 4 (MEN4) Vania Nosé, MD, PhD and Michelle Menon Miyake, MD ADRENAL GLAND AND PARAGANGLIA 768 Beckwith-Wiedemann Syndrome Patricia Nogueira de Sa, MD and Vania Nosé, MD, PhD 776 Carney Complex Vania Nosé, MD, PhD 784 Hereditary Neuroblastoma Vania Nosé, MD, PhD 788 Hereditary Paraganglioma/Pheochromocytoma Syndromes Vania Nosé, MD, PhD 796 Multiple Endocrine Neoplasia Type 5,MAX-Related Vania Nosé, MD, PhD 798 Neurofibromatosis Type 1 Michelle Menon Miyake, MD and Vania Nosé, MD, PhD 806 von Hippel-Lindau Syndrome Vania Nosé, MD, PhD 814 SDH-Deficient Pheochromocytoma and Paraganglioma Vania Nosé, MD, PhD and Arthur S. Tischler, MD PANCREAS 820 Glucagon Cell Hyperplasia and Neoplasia Vania Nosé, MD, PhD 824 Hereditary and Familial Pancreatic Cancer Syndrome Daniel C. Chung, MD and Vania Nosé, MD, PhD 828 MAFA-Related Familial Insulinomatosis Vania Nosé, MD, PhD 830 Pancreatic Neuroendocrine Tumor Syndromes 842 Ectopic (Paraneoplastic) Syndromes Lori A. Erickson, MD

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Book SynopsisTable of ContentsSECTION 1. Neuropalliative care as a new field 1. Key concepts and opportunities 2. Neuropalliative care: Defining an emerging field 3. The neuropalliative multidisciplinary team - Members and their roles 4. Delivery models of neuropalliative care 5. International models of neuropalliative care 6. What palliative care physicians wish neurologists knew 7. What neurologists wish palliative care physicians knew 8. When to initiate palliative care in neurology SECTION 2. Goals of care and advance care planning, prognostication, and end of life 9. Advance care planning in neurologic illness 10. Prognostication in brain tumors 11. Prognostication in dementia 12. Prognostication in neurology 13. End-of-life and hospice care for neurologic illness 14. Responding to requests for hastened death in patients living with advanced neurologic disease

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Book SynopsisTable of ContentsPart 3 Basic Science Development 1. Role of rodent models in advancing precision medicine for Parkinson disease 2. The allure and pitfalls of the prion-like aggregation in neurodegeneration 3. The shift to a proteinopenia paradigm in neurodegeneration 4. Disease mechanisms as subtypes: Lysosomal dysfunction in the endolysosomal Parkinson disease subtype 5. Disease mechanisms as subtypes: Mitochondrial and bioenergetic dysfunction 6. Disease mechanisms as subtypes: Immune dysfunction in Parkinson disease 7. Disease mechanisms as subtypes: Inflammation in Parkinson disease and related disorders 8. Disease mechanisms as subtypes: Microbiome 9. LRRK2: Genetic mechanisms vs genetic subtypes 10. Genetic mechanism vs genetic subtypes: The example of GBA 11. Subtyping monogenic disorders: Huntington disease Part 4 Clinical Trials and Therapeutic Approaches 12. Disease-modifying vs symptomatic treatments: splitting over lumping 13. Restorative cell and gene therapies for Parkinson disease 14. The promise and challenges of extracellular vesicles in the diagnosis of neurodegenerative diseases 15. Therapeutic potential of extracellular vesicles in neurodegenerative disorders 16. Lessons from antiamyloid-ß immunotherapies in Alzheimer disease 17. Lessons from immunotherapies in multiple sclerosis 18. Adaptive clinical trials and master protocols 19. Role of novel endpoints and evaluations of response in Parkinson Disease 20. Leveraging the regulatory framework to facilitate drug development in Parkinson disease

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Book SynopsisTable of ContentsSECTION I Overview of Polycystic Syndrome 1 Introduction to Polycystic Ovary Syndrome 2 Polycystic Ovary Syndrome Phenotypes 3 Polycystic Ovary Syndrome Adolescents SECTION II Pathogenesis and Clinical Presentation 4 Pathophysiology of Polycystic Ovary Syndrome 5 Interplay of Adipocytokines With Polycystic Ovary Syndrome 6 Crosstalk between Oxidative Stress and Chronic Inflammation in Pathogenesis of Polycystic Ovary Syndrome 7 Polycystic Ovary Syndrome and Subfertility: Ovulation Dysregulation and Fertility Problems (Clinical Features and Pathophysiology) 8 Clinical Features and Presentation of Polycystic Ovary Syndrome 56 9 Diagnostic Criteria for Polycystic Ovary Syndrome 10 Polycystic Ovary Syndrome and Metabolic Syndrome: Risks in Later Life 11 Polycystic Ovary Syndrome and Mental Health 12 Polycystic Ovary Syndrome and Nonalcoholic Fatty Liver Disease 13 Male Polycystic Ovary Syndrome Equivalent SECTION III Management of Polycystic Ovary Syndrome and Associated Comorbidities 14 Pharmacologic Management of PCOS: Menstrual Irregularities 15 Pharmacologic Management for Polycystic Ovary Syndrome: Hirsutism and Acne 16 Pharmacologic Management for Polycystic Ovary Syndrome: Weight Loss 17 Role of Insulin Sensitizers in the Management of Polycystic Ovary Syndrome 18 Cardiovascular Risk Reduction in Polycystic Ovary Syndrome 19 Management of Subfertility in Polycystic Ovary Syndrome 20 Management of Associated Risks of Pregnancy in Polycystic Ovary Syndrome 21 Importance of Lifestyle Modifications 22 Role of Complementary and Alternative Medicine in Polycystic Ovary Syndrome 23 Evidence-Based Recommendations for Clinical Practice (Future Directions: Research and Practice) SECTION IV Global Approach to Polycystic Ovary Syndrome 24 Polycystic Ovary Syndrome in South Asians 25 Situation Analysis of Polycystic Ovary Syndrome in Central and East Asia 26 Situational Analysis of Polycystic Ovary Syndrome in Southeast Asia 27 Situation Analysis of Polycystic Ovary Syndrome in Western Asia 28 Situation Analysis, Cultural Beliefs, Lifestyle,and the Psychological Impact of Polycystic Ovary Syndrome in Europe 29 Global Approach to Polycystic Ovary Syndrome in Africa 30 Polycystic Ovary Syndrome in North America

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Book SynopsisTable of ContentsSECTION I: EPIDEMIOLOGY AND PREVENTIVE STRATEGIES 1. General Population and Global Cardiovascular Risk Prediction 2. Diet and Hypertension 3. Exercise and Hypertension 4. Hypertension in Women SECTION II: PATHOPHYSIOLOGY 5. Pathophysiology of Hypertension 6. Genetics of Hypertension 7. Inflammation and Immunity in Hypertension SECTION III: DIAGNOSIS AND EVALUATION 8. The Environment and High Blood Pressure 9. Office Blood Pressure Measurement 10. Home Monitoring of Blood Pressure 11. Ambulatory Blood Pressure Monitoring in Clinical Hypertension Management 12. White Coat and Masked Hypertension 13. Renovascular Hypertension and ISchemic Neuropathy 14. Secondary Hypertension: Primary Hyperaldosteronism and Mineralocorticoid Excess States 15. Secondary Hypertension: Pheochromocytoma and Paraganglioma 16. Sleep Disruption and Blood Pressure SECTION IV: RISK STRATIFICATION 17. The Natural History of Untreated Hypertension 18. Isolated Systolic Hypertension 19. Assessment of Hypertension-Mediated Organ Damage SECTION V: ANTIHYPERTENSIVE THERAPY 20. Diuretics Therapy 21. Calcium Channel Blockers 22. Renin Angiotensin Aldosterone System Blockers 23. Aldosterone and Hypertension 24. ß-Blockers, Central Sympathetic Agents,and Direct Vasodilators 25. Peripheral Alpha Blockers 26. Initial Combination Therapies 27. Devices Therapies for Hypertension 28. The Treatment of Hypertension With Nutrition, Nutritional Supplements, and Lifestyle SECTION VI: HYPERTENSION MANAGEMENT APPROACHES 29. Approach to Difficult to Manage Primary Hypertension 30. Team-Based Care for Hypertension Management 31. Medication Adherence: Focus on Improvement 32. Digital Health and Telemedicine for Hypertension SECTION VII HYPERTENSION MANAGEMENT WITH COMORBIDITIES 33. Ischemic Heart Disease 34. Heart Failure 35. Hypertension and Chronic Kidney Disease Including Dialysis 36. Transplant Hypertension 37. Obesity and Hypertension: Pathophysiology and Treatment 38. Cerebrovascular Disease 39. Diabetes Mellitus: Management of Hypertension in Diabetes 40. Onco-Hypertension: Anticancer Therapy-Associated Hypertension 41. Autonomic Dysfunction and Orthostatic Hypotension 42. Dyslipidemia 43. Aorta and Peripheral Arterial Disease in Hypertension SECTION VIII SPECIAL POPULATIONS 44. Hypertension in Pregnancy 45. Hypertension in Older People 46. Hypertension in African Americans 47. Resistant Hypertension 48. Hypertensive Emergencies and Urgencies 49. Hypertension in Children: Diagnosis and Treatment Appendix Meta-Analyses of Blood Pressure Lowering Trials Index

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Book Synopsis

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Book Synopsis

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Book SynopsisTable of ContentsSection I. Assessment of the respiratory system in neurological disorders 1. Pulmonary function testing in neuromuscular disease 2. Electrophysiological assessment of respiratory function Section II. Primary breathing disorders 3. Apnea of prematurity and sudden infant death syndrome 4. Developmental diseases affecting the respiratory system: CCHS and ROHHAD 5. Central sleep apnea 6. Obstructive sleep apnea Section III. Neurological disorders affecting respiration 7. Breathing disturbances in Rett syndrome 8. Sudden unexpected death in epilepsy: Respiratory mechanisms 9. Multiple Sclerosis and related disorders 10. Stroke and breathing 11. Breathing disorders in neurodegenerative diseases 12. Spinal cord injury and degenerative cervical myelopathy 13. Motor neuron, peripheral nerve, and neuromuscular junction disorders 14. Phrenic nerve paralysis and phrenic nerve reconstruction surgery Section IV. Cardiovascular disorders affecting respiration 15. Sleep and breathing disorders in heart failure 16. Neurological effects of respiratory dysfunction 17. Neurologic complications of coronavirus and other respiratory viral infections Section V. Treatment considerations for respiratory dysfunction in neurological disorders 18. Noninvasive and invasive mechanical ventilation for neurologic disorders

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