Education Books

Book SynopsisJourneys that begin in brokenness rarely follow a straight road to healing. There are twists and turnsand setbackson the path of repentance.Night Drivingtells the story of a pastor and seminary professor whose moral failures destroyed his marriage and career, left his life in ruins, and sent him spiraling into a decade-long struggle against God. Forced to fight the demons of his past in the cab of the semi-truck he drove at night through the Texas oil fields, Chad Bird slowly began to limp toward grace and healing. Drawing on his expertise as an Old Testament scholar, Bird weaves together his own story, the biblical story, and the stories of fellow prodigals as he peels back the layers of denial, anger, addiction, and grief to help readers come face-to-face both with their own identities and with the God who alone can heal them.

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Book SynopsisTable of ContentsSECTION 1 Structural and Functional Development 1 Terminology 2 Anatomy 3 Embryology of the Heart 4 Etiology of Congenital Cardiac Disease 5 Myocardium and Development 6 Physiology of the Developing Heart SECTION 2 Prenatal Congenital Heart Disease 7 Magnetic Resonance Assessment of the Fetal Circulation in Congenital Heart Disease 8 Imaging and Quantifying the Fetal Circulation in Congenital Cardiac Disease: Ultrasound 9 Pharmacologic Intervention in the Fetus 10 Percutaneous Intervention in the Fetus, Including Postnatal Management 11 The Placenta in Congenital Heart Disease 12 Optimizing Prenatal Support of the Mother and Family SECTION 3 General Topics 13 Prevalence of Congenital Cardiac Disease 14 Economic Implications of Congenital Heart Disease in Developed Countries 15 Prematurity and Cardiac Disease 16 Surgical Techniques 17 Diagnostic Catheterization, Including Adults With Congenital Cardiac Disease 18 Interventional Techniques 19 Cross-Sectional Echocardiography and Doppler Imaging 20 Three-Dimensional Echocardiography 21 Magnetic Resonance Imaging and Computed Tomography: Diagnostic Imaging, Image Management, and Assessment of Physiology and Function 22 Electrophysiology, Pacing, and Defibrillation 23 Cardiopulmonary Exercise Testing 24 Pediatric Cardiovascular Data, Analysis, and Critical Appraisal of the Literature 25 Cardiovascular Risk Factors in Youth SECTION 4 Specific Lesions 26 Isomerism of the Atrial Appendages 27 Anomalous Systemic Venous Return 28 Pulmonary Venous Abnormalities 29 Interatrial Communications 30 Division of Atrial Chambers ("Cor Triatriatum”) 31 Atrioventricular Septal Defects 32 Ventricular Septal Defect 33 Diseases of the Tricuspid Valve 34 Diseases of the Mitral Valve 35 Tetralogy of Fallot With Pulmonary Stenosis 36 Tetralogy of Fallot With Pulmonary Atresia 37 Transposition 38 Congenitally Corrected Transposition 39 Double-Outlet Ventricle 40 Common Arterial Trunk 41 Arterial Duct: Its Persistence and Its Patency 42 Pulmonary Stenosis 43 Pulmonary Atresia With Intact Ventricular Septum 44 Congenital Anomalies of the Aortic Valve and Left Ventricular Outflow Tract 45 Coarctation and Interrupted Aortic Arch 46 Congenital Coronary Anomalies 47 Vascular Rings, Pulmonary Arterial Sling, and Related Conditions 48 Artery of the Fifth Aortic Arch 49 Abnormal Positions and Relationships of the Heart 50 Arteriovenous Communications 51 Other Malformations of the Ventricular Outflow Tracts 52 Cardiac Tumors 53 Kawasaki Disease 54 Acute Rheumatic Fever 55 Chronic Rheumatic Heart Disease 56 Infective Endocarditis 57 Pericardial Diseases in Children 58 Aortopathies in Pediatric Cardiology and Cardiac Surgery 59 Cardiologic Aspects of Systemic Disease 60 Systemic Hypertension SECTION 5 Heart Failure and Transplantation 61 Cardiomyopathies 62 Cardio-oncology 63 Myocarditis 64 Acute Circulatory Failure: Pharmacologic and Mechanical Support 65 Chronic Heart Failure: Physiology and Treatment 66 Chronic Mechanical Circulatory Support 67 Heart and Heart-Lung Transplantation SECTION 6 Functionally Univentricular Heart 68 Introduction: The "Fontan Pathway 69 Anatomic Considerations in the Functionally Univentricular Heart 70 Physiologic Principles to Maximize Outcome in Patients With a Functionally Univentricular Heart 71 Fontan Pathway From Birth Through Early Childhood 72 Interstage Management 73 Longer-Term Outcomes and Management for Patients With a Functionally Univentricular Heart SECTION 7 Beyond the Heart 74 Systemic Circulation 75 Pulmonary Hypertension 76 Neurodevelopmental and Psychosocial Outcomes in Children and Young Adults With Complex Congenital Cardiac Disease 77 Congenital Cardiac Disease in the Setting of Genetic Syndromes 78 Acute and Chronic Renal Consequences of Cardiac Disease in Children 79 Pharmacogenetics in the Treatment of Congenital and Acquired Cardiac Disease During Childhood 80 Pregnancy and Congenital Heart Disease 81 Preparing the Young Adult With Complex Congenital Cardiac Disease to Transfer From Pediatric to Adult Care 82 Psychological and Social Aspects of Pediatric Cardiac Disease 83 Ethical Issues in Pediatric Cardiology and Congenital Heart Disease 84 Clinical Care Pathways Supporting the Care of Children and Young People With Congenital Heart Disease 85 Discharge Planning, Communications With the Team Providing Care in the Ambulatory Setting and the "Medical Home 86 Growth and Nutrition 87 Quality Improvement in Congenital Cardiac Disease 88 Global Burden of Pediatric Heart Disease and Pediatric Cardiac Care in Low- and Middle-Income Countries 89 Screening in Pediatric and Congenital Cardiac Disease 90 Anesthetic Considerations for Cardiac and Noncardiac Surgery in the Child With Congenital Cardiac Disease 91 Telemedicine in Pediatric Cardiology

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About our authors Roy L. Alson, PhD, MD, FACEP, FAEMS, is a professor of emergency medicine at Wake Forest University School of Medicine and the former director of the Office of Prehospital and Disaster Medicine, also at Wake Forest. He is also an associate professor at the Childress Institute for Pediatric Trauma at Wake Forest University and an adjunct associate professor in the Department of Military Medicine at Rocky Vista University College of Osteopathic Medicine, in Parker, Colorado. Dr. Alson received his bachelor's degree from the University of Virginia in 1974 and both his PhD and an MD from the Bowman Gray School of Medicine of Wake Forest University (1982, 1985). He completed his residency in emergency medicine at Allegheny General Hospital in Pittsburgh, Pennsylvania, and is board certified in both emergency medicine and emergency medical services by the American Board of Emergency Medicine. Dr. Alson's EMS career began in the early 1970

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Book SynopsisUniversally recognized as the gold standard among word-for-word translations, the beloved New American Standard Bible, 1995 Edition, is now easier to read with Zondervan’s exclusive NASB Comfort Print typeface.

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Book SynopsisIllustrated with high-quality photomicrographs, Differential Diagnosis in Small Animal Cytology: The Skin and Subcutis is a comprehensive resource for identifying through cytology the most common cutaneous and subcutaneous diseases of dogs and cats. With key points describing the main clinical and cytological features of each lesion, the book provides lists of differential diagnoses, including diagnostic algorithms, and handy 'hints and tips' boxes. It is also enriched by chapters on the correct use and maintenance of the microscope, and techniques of collection and preparation of cytological specimens, making the book a valuable resource for veterinary pathologists (clinical and anatomic), residents, veterinary undergraduate students and small animal practitioners. Key features: -Over 130 photomicrographs of the most common skin and subcutaneous lesions to help with diagnosis. -Ideal reference book with concise descriptions of each lesion. -Organised into key bullet points to facilitate use during diagnostic work, or as a revision aid.Table of ContentsPart I: BASIC PRINCIPLES OF CYTOLOGY 1: Guide to the Choice and Correct Use of the Microscope (Ian Baldwin) 2: Collection, Preparation and Staining of Cytology Specimens 3: Guidelines to Approach Cytology Smear Examination 4: Cytological Criteria of Malignancy Part II: CYTOLOGY OF SKIN AND SUBCUTIS 5: Skin Anatomy 6: Cutaneous and Subcutaneous Inflammatory Lesions 7: Cutaneous Cysts, Tumour-like Lesions and Response to Tissue Injury 8: Cutaneous Epithelial Tumours 8.1: Tumours without epidermal or adnexal differentiation 8.2: Epidermal tumours 8.3: Follicular tumours 8.4: Sebaceous tumours 8.5: Apocrine gland tumours 8.6: Clear cell adnexal carcinoma (dog) 8.7: Merkel cell tumour 8.8: Diagnostic algorithms 9: Cutaneous and Subcutaneous Mesenchymal Tumours and Other Neoplasms 9.1: Mesenchymal tumours 9.2: Histiocytic tumours 9.3: Melanocytic tumours 10: Cutaneous and Subcutaneous Round Cell tumours 11: Cutaneous Metastatic Lesions 12: Suggested Reading and References

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Book SynopsisDefiningthe kingdom of God as the interplay of the king's power over the king's people in the king's place, this volume helps readers understand God's purpose for the world.

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Book SynopsisTable of ContentsClinical evaluation of the lower urinary tract Basic structure, function and control of the lower urinary tract Urodynamic procedures Pressure / flow cystometry Storage disorders and incontinence Voiding disorders and bladder outlet obstruction Sensory disorders The contracted bladder Neurogenic bladder disorders Paediatric urodynamics Appendices

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Book Synopsis‘This splendid and often moving work of history… Schama has a gift for combining novelistically colourful detail, serious analysis and wryly amusing asides’ Daily Telegraph   ‘Superb’ Observer   ‘Extraordinary… A meticulous retelling of a terrible yet scientifically innovative period… Makes an urgent case for building a better future on our toxic past’ Guardian   ‘This is history of the best sort – humanly engaged but never sentimental’ Mail on Sunday Cities and countries engulfed by panic and death, desperate for vaccines but fearful of what inoculation may bring. This is what the world has just gone through with Covid-19. But as Simon Schama shows in his epic history of vulnerable humanity caught between the terror of contagion and the ingenuity of science, it has happened before. Trade Review‘Superb' * Guardian *'A splendid and often moving work of history . . . Schama has a gift for combining novelistically colourful detail, serious analysis, and wryly amusing asides’ * The Telegraph *‘The histories Schama weaves together in this very personal and rather wonderful book should encourage us to know what is possible, in astonishingly short periods of time, if compounding human talent is channelled to good and universal ends’ * Literary Review *‘This is history of the best sort – humanly engaged but never sentimental’ * Mail on Sunday *'With the aplomb of a young A. J. P. Taylor, Schama neatly balances the obligation to disparage empire with the historian’s love of valorous action. He pricks the pretensions of the Raj, whose grandees thought they had materially bettered the lives of Indians; but he handsomely acknowledges the human efforts expended, in crowded slums and roadside clinics, pursuing that fond vision' * Financial Times *'Schama’s now-familiar approach, with its over-the-shoulder perspective and deluge of local detail, gives a pleasing verisimilitude to his stories of jostling individuals, ideas and institutions. It is Haffkine’s political fall that provides the book’s strongest passages. The colonial administration – a bureaucratic machine for misery, terrified of resistance – was willing to mobilise against what it saw as a foreign threat, even with millions of lives, and its own legitimacy, in the balance. We see the reactionary drive towards both self- and collective harm repeat on the scale of the nation, institution and individual, in Haffkine’s world as well as our own. History suggests there are other paths, imperfect and difficult though they might be, if we could only recognise them' * New Statesman *'A fascinating story of vaccines’ spread' * The Economist *‘Do yourself a favour, buy this book . . . it’s vast and terrifying and somehow beautiful, and it reads like a Ted Talk all-timer, but instead of a blank screen you’re left with this beautiful bow to untie and book to read’ * Irish Times *‘Delves into the history of pandemics and their cures, through the gripping personal narratives of some fascinating individuals’ * Radio Times *’Schama’s account makes the case for learning from history and opening our minds to ideas that come from strange places. Whether we like it or not, we’re all connected, now more than ever' * The Times *'His account of the individuals who have helped curb the devastating effects of widespread infections – often defying medical hierarchies and courting controversy in the process – ultimately presents an inspiring and hopeful read' * Perspective *'Schama’s skill as a narrator makes for an effortless ride between the minutiae of particular diseases, their spread throughout communities, and the story of the forces of biology in shaping global history’ * Times Literary Supplement *

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Book SynopsisAre you wondering what the hell has happened to you since you hit 40? You’re not alone! Millions of women over 40 worldwide are suffering needlessly. Stressed out and exhausted, struggling to lose weight, suffering mood swings and PMS, or hot flushes and night sweats, life can seem like one big struggle. What many women don’t realize is that the key to sustainable weight loss, vitality and balance is not the latest fad diet or fitness programme. For women over 40, the answer is to take back control of your hormones! It’s Not You, It’s Your Hormones is the essential guide for every woman over 40, providing natural and practical solutions to fight fat, fatigue and hormone havoc.Trade ReviewAmazon reviews: 'A really informative and easy to read book with loads of information to help you understand whats going on!Practical solutions and easy steps to follow all clearly set out in both book and kindle versions. The medical information goes a step further to back up the reasons for doing things and for me I found that really helpful.Nicki's 30 days to happy hormones plan takes the book on further and you really can make a great difference by adopting these small changes and when you understand how to do this its easy to commit. Nicki is realistic in her approach to life and living by the 80:20 rule which means you can experiment with the plan to suit your lifestyle too.''Brilliant, sensible advice and easy to understand. Really interesting too. It’s actually changed my whole relationship with food.''I never realised I could control my hot flushes through diet without resorting to HRT. Thank god I went to Amazon before phoning the doctor!Nicki not only knows her stuff, she is passionate about it and this comes through reading. The book is written in an encouraging way - very personable with just enough science to back the reasons why.Her passion for wanting you, the reader, to understand your body and the effects hormones are having on it, is quite addictive and I almost found myself improving through osmosis.I would thoroughly recommend this book to all women suffering from perimenopause/menopause.''I'd highly recommend this book to any ladies out there struggling to get to grips with their hormones and the horrible side effects we tend to just "live with" as we think that it's just part of being a women. Nicki helps explain the science behind hormonal imbalances in a really accessible, easy to understand way that really makes you go "ah-ha"! Her hormone balancing plan is easy to follow and full of so many helpful tips and information to make changes achievable and sustainable. I loved the lists and blocks of info as these were great to refer to for quick guidance and the recipes are delicious and use simple ingredients you can easily get hold of. Overall a fantastic read for anyone in need of more energy, a better mood and keen to lose a few extra pounds!''Most doctors know very little about hormones and like to pretend it's our age and well, what can you do? A great deal as it happens and this book is brilliant for giving clear and indepth explanations and solutions without blinding you with science. Nicki Williams really does know her stuff and every woman at the point of sheer frustration and with a myriad of symptoms should look no further than this book. You really can help yourself!''Crystal clear explanation with actionable steps to do something about it all! I love Nicki's clarity and examples. I think this is also for women in their 20's and 30's, or even older than 40 too! We all need to know at every age. And it's so good to know it's not lack of willpower. Our bodies are working as designed for cavewomen days. The fact that our days and our environment has changed, doesn't mean that our survival instincts and hormones work differently now. So incredible to see how much our present and future are driven by our deep past!''The premise of this powerful, well-researched book is simple: when a woman’s hormones are in sync, she’s a powerhouse, but when they’re out of whack, they wreak havoc on her body and mind. The effective, easy-to-follow plan to balance your hormones to reclaim your life is worth its weight in gold. A “must read” for every woman over 40.''As a business owner, my health is my biggest business asset and my energy is my number one resource! For 40+ women like me, who want to really understand what their body needs at 40+ compared to our twenties to stay healthy and full of energy, Nicki's expertise, wisdom and practical advice is a god send.''For anyone who wants to manage their menopause without using HRT this book is a godsend. It is packed with lots of detail and practical help. It’s not just about the obvious menopause/peri menopause issues. It’s about looking and feeling your best, and having all the energy you want to lead a fun life.On my first read I scanned a lot of it to get a general overview. The summaries at the end of each chapter were very helpful. But the book is so jam packed with information that I’m now going back to read certain areas in more detail. It’s definitely going to be my hormone resource going forwards.Nicki really does know her stuff, and can convey it in a down to earth manner.I thoroughly recommend this book to anyone over 40 who isn’t feeling quite as good as they would like.''I loved this book, really easy to read and well laid out.I had tried to read about this subject before and basically gave up as It all seemed so confusing and there was too much information to take in. So I so appreciated the Summary at the end of each chapter.I wish Happy Hormones had been around for me years ago, as I and many women were not even aware Peri-Menopause existed.My summary: A very well researched book with bang up to date Information. I definitely recommend it.'"I thought that this book was really informative, it helped me understand why I wasn't feeling normal! I found some useful information and tips.""...A “must read” for every woman over 40.""Easy to read and full of useful information to help through the menopause. I have made some of the positive changes recommended and am feeling the benefits already."The book is well written, easy to read and very informative. I have made some of the changes recommended and can see a difference in how I feel. Definitely recommend!"Table of ContentsIntroduction A quick guide to getting the most out of this book Part 1: Here’s the thing about hormones Chapter 1: Hormones 101 – what are they and why do they aff ect us so much? Chapter 2: Take the quiz – find out if you have a hormone imbalance Chapter 3: Meet your Feisty 4 Part 2: Why your hormones need help Chapter 4: The big dietary and lifestyle saboteurs Chapter 5: Ditch the diet – why dieting and extreme exercise is not working for you any more Chapter 6: Your liver and gut – why they are important Part 3: Your hormone-balancing plan Chapter 7: The Happy Hormone Code – your simple four-step nutrition and lifestyle solution Step 1 - Eat Step 2 - Rest Step 3 - Cleanse Step 4 - Move Chapter 8: Mindset – get your head sorted Chapter 9: Keeping it going Part 4: Beyond diet and lifestyle Chapter 10: Get yourself tested Chapter 11: How supplements can help Chapter 12: Hormone Replacement Therapy – the low-down A final word Resources: Recipes; Low GL Guide; The Happy Hormone Plate; Home Thyroid Test; The Happy Hormones Manifesto; Website and book recommendations References Index

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Book SynopsisEssential guide to a condition characterised by fluid retention and chronic swelling, explaining its link to diet and exercise and offering lifestyle adjustments and self-management strategies.

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Book SynopsisJenny Rose is Associate Professor of Religion at Claremont Graduate University and Visiting Associate Professor of Religion at Stanford University. She is the author of The Image of Zoroaster: The Persian Mage Through European Eyes (2000).Table of ContentsAcknowledgements Zoroastrianism: An Introduction List of Abbreviations Maps I: Zoroastrians Present and Past II: The Ancient Persians: Truth-Tellers and Paradise-Builders III: A Zoroastrian Presence from Seleucia to Sistan: The Parthian Period IV: Eranshahr: The Sasanian Center of the World V: The Zoroastrians of Central Asia VI: Gabr-Mahalle: Zoroastrians in Islamic Iran VII: Parsipanu: Zoroastrians in India VIII: Zoroastrians Present: Revisited IX: Zarathushtra Present and Past Appendix 1: Textual Timeline Appendix 2: The Five Gathas Appendix 3: Outline of the Yasna Appendix 4: A Selective Historical Timeline Glossary of Names and Terms Notes Select Resources Index

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Book SynopsisFrom the publisher of the Jordanville Prayer Book and A Psalter for Prayer comes the perfect devotional companion for travel and everyday life. This truly pocket edition brings together prayers for use throughout the day with all one hundred fifty Psalms of David adapted from the classic Miles Coverdale translation.Table of ContentsMorning Prayers Prayers during the Day Prayers before Sleep The Prayer of the Optina Elders The Daily Prayer of Hieroschemamonk Parthenios Sunday Troparia and Kontakia Daily Troparia and Kontakia Troparia and Kontakia of the Immovable Great Feasts Troparia, Kontakia, Prayers, and Stichera from the Triodion Passion Week Troparia and Kontakia The Hours of Holy Pascha Troparia and Kontakia from the Pentecostarion Supplicatory Canon to Our Lord Jesus Christ Supplicatory Canon to the Most Holy Theotokos Canon to the Guardian Angel Akathist to Our Sweetest Lord Jesus Akathist to Our Most Holy Lady the Theotokos Canon of Repentance to Our Lord Jesus Christ The Order of Preparation for Holy Communion The Prayers after Holy Communion The Order for Reading Canons and Akathists When Alone The Psalms of David

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Book SynopsisWe want to be healthy. We want to be lean. And we want to lose that annoying fat around our bellies. Now we can! The Lose Your Belly Diet is built around a very clear, research-based concept: eating food that nourishes and protects the microbes in your gut paves the way for weight loss and a slimmer middle. Most importantly, having great gut health is linked to good health and wellbeing throughout your body.Scientists in this rapidly growing field are finding connections between the gut microbiome and a healthy immune system and gastrointestinal system, as well as autoimmune diseases (such as rheumatoid arthritis and inflammatory bowel disease), allergies and asthma even cancer. And with every study that is published, they are convinced that a healthy gut leads to a healthy body. Indeed, when your gut is happy, your skin glows with health and you look and feel younger.The Lose Your Belly Diet includes meal plans, diet recommendations andTrade ReviewMore than a diet, this is a plan for feeling your best. I highly recommend it. -- Dr Phil McGraw

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Book SynopsisThe rollicking memoir from the cardiologist turned legendary scientist and winner of the Nobel Prize that revels in the joy of science and discovery. Like Richard Feynman in the field of physics, Dr. Robert Lefkowitz is also known for being a larger-than-life character: a not-immodest, often self-deprecating, always entertaining raconteur. Indeed, when he received the Nobel Prize, the press corps in Sweden covered him intensively, describing him as “the happiest Laureate.” In addition to his time as a physician, from being a "yellow beret" in the public health corps with Dr. Anthony Fauci to his time as a cardiologist, and his extraordinary transition to biochemistry, which would lead to his Nobel Prize win, Dr. Lefkowitz has ignited passion and curiosity as a fabled mentor and teacher. But it's all in a day's work, as Lefkowitz reveals in A Funny Thing Happened on the Way to Stockholm, which is filled to the brim with anecdotes and energy, and gives us a glimpse into the life of one of today's leading scientists. Trade Review"Cardiologist-turned-biochemist, Robert Lefkowitz won the 2012 Nobel Prize in Chemistry for showing how adrenaline works through stimulation of specific receptors, with huge implications for drug discovery. Yet he calls himself 'an accidental scientist,' because he trained as a physician. Instead of being drafted to the Vietnam War, he served at the US National Institutes of Health. His autobiography is a vividly anecdotal account, influenced by a supervisor’s lesson that data do not tell a story: 'A story is something you impose on the data.'" -- Andrew Robinson * NATURE *“Lefkowitz unveils the teamwork, persistence, and labors of love that go into living a life of significance. By turns funny and moving, this book has the power to inspire.” -- Mike Krzyzewski, Head Coach, Men’s Basketball, Duke University"This vivid tale shines with personality. Rarely has science been treated with such a winning blend of humor and humanity." * Publishers Weekly *"Lefkowitz is an avid and inveterate storyteller. Told with humor and humility, what shines through most is his love of stories. His passion for science and discovery, for helping people, and for celebrating stories is infectious." * Booklist *“An engaging Nobel Prize-winning journey of a life in medicine and science. Joyous, insightful, and irreverent, Lefkowitz describes the enormous impediments to challenging established dogma and legendary elders as well as the art and satisfaction of mentoring young scientists. For both lay readers and professional scientists, this book presents a narrative that will delight and that offers a goldmine of wisdom.” -- Robert Horvitz, Ph.D., Massachusetts Institute of Technology, Investigator of the Howard Hughes Medical Institute; Nobel Prize in Physiology or Medicine (2002)“Lefkowitz’s life is testament to the joy of science. The book is a page-turner, a riveting account of a life well-lived. It is a story of stories, a tale of greatness.” -- Roger D. Kornberg, Ph.D., Stanford University, Nobel Prize in Chemistry (2006)“In this engaging and often rollicking tale, Bob Lefkowitz recounts how the Vietnam War transformed him from a dedicated young physician into an enthusiastic, ambitious, and highly successful scientist whose discoveries have altered our understanding of cell function and approaches to drug development. Arriving at a time when the need to convert physicians into scientists is greater than ever, this book can do more than just entertain and instruct: it can inspire young doctors to remake their careers.” -- Harold Varmus, M.D., Lewis Thomas University Professor, Weill Cornell Medicine; Nobel Prize in Physiology or Medicine (1989); Author of The Art and Politics of Science“More than just a heartwarming and thrilling chronicle of a great physician-scientist, Lefkowitz has written a story-based leadership guide for any aspiring mentor. A testament to the power of building enduring excellence by believing in, championing, and developing others.” -- Sanyin Siang, Leadership Coach and author of The Launch Book“A spell-binding memoir, packed with deep insights and charged with the thrill of discovery. This is a tale told from the pinnacle of human achievement, that also serves as a master-class in humility and overcoming tragedy—all interwoven with laugh-out-loud anecdotes. Lefkowitz is a brilliant and charming storyteller, with an indomitable passion for living, and wisdom for the ages.” -- Karl Deisseroth, M.D., Ph.D., Stanford University, Winner of the Kyoto Prize and the Heineken Prize; Author of Projections“In this entertaining book, Nobelist Bob Lefkowitz recounts how he became a passionate and renowned physician-scientist. He unveils the secret to his scientific stardom in a series of engrossing stories spanning his fifty-year career. No tale is left untold—many are amusing, some might raise a few eyebrows.” -- Joseph L. Goldstein, M.D., and Michael S. Brown, M.D., U.T. Southwestern Medical Center, Nobel Prizes in Physiology or Medicine (1985)“Lefkowitz provides joyous remembrance of his amazing career as a physician-scientist. Interlaced with vignettes of personal sacrifice, growth, and friendship is the story of the seminal discoveries that culminated in science’s highest award. A beautiful story of family, hard work, and steadfast optimism.” -- Christine Seidman, M.D., Professor, Harvard Medical School, Director, CV Genetics Center Brigham and Women’s Hospital“How does a brilliant young physician accidentally get hooked on research? Bob Lefkowitz's life-altering shift changed not only his life but the lives of hundreds of his trainees. From the dazzling way adrenaline controls critical body functions to the thrill of his Nobel Prize win, this engaging book will help you better understand how physician scientists dedicate their careers to understanding human biology and enhancing human health." -- P. Roy Vagelos, M.D., Retired Chairman and CEO, Merck & Co.; Chairman of the Board, Regeneron Pharmaceuticals“Lighthearted, yet profoundly personal and moving, Lefkowitz’s memoir shares the secret recipe for winning a Nobel prize—two parts genius, one part audacity in challenging authority, one part insightful and supportive mentoring, a splash of good luck, and ten parts resilience and persistence. Bob Lefkowitz is at the top of the list of the extraordinary cadre of physicians turned scientists who ushered in the modern biotechnology revolution.” -- Barry S. Coller, M.D., David Rockefeller Professor of Medicine, Rockefeller University, Physician-in Chief, Rockefeller University Hospital"The odds of a scrappy kid growing up in the Bronx winning a Nobel Prize are overwhelmingly small. How Bob Lefkowitz managed to do this is revealed in this delightfully rich and moving book allowing the reader to understand Bob’s intelligence, warmth, and complexity. If you read one book this year, choose this one. It will fill you with joy, hope, and give you a new friend.” -- Ralph Snyderman, M.D., Professor of Medicine, Chancellor Emeritus, Duke University“A blend of comedy, history, and tragedy, this book is much more than a delightfully amusing tale of a bright kid from the Bronx who ultimately wins a Nobel Prize. Bob Lefkowitz’s message is of the utmost importance. U.S. taxpayer dollars funded a unique cadre of young physicians—'the Yellow Berets’—whose discoveries have led to revolutionary therapies for heart disease, cancer, diabetes, impotence, neurodegeneration, HIV, and coronavirus, all while training the next generation of medical scientists. Reading this book shows that investments in science will continue to save the world.” -- Peter Agre, M.D., Professor and Director, Johns Hopkins Malaria Research Institute, Bloomberg School of Public Health; Nobel Prize in Chemistry (2003)“Robert Lefkowitz’s memoir is a rollicking, absorbing read. It turns out many funny things happened on his way to Stockholm. Beautifully written, this book demonstrates the importance of humor, humility, and humanity in the pursuit of scientific discovery." -- Jerry Speyer, Chairman, Tishman-Speyer"A deeply personal perspective of events, people, thoughts, and actions that have created an era of major scientific breakthroughs. Full of insights and revelations about the milieu that underlies today’s biomedical revolution, from a key participant. Written with a candor and style that make Bob Lefkowitz’s life adventures as a physician-scientist a delight to read.” -- Stanley N. Cohen, M.D., Professor of Genetics and Medicine, Stanford University“Bob Lefkowitz is a legend in his own time. In addition to his clinical background as an MD and acknowledged scientific mettle resulting in a Nobel Prize, he is a renowned raconteur. Bob also has an excellent sense of humor, and these twin skills have made him a highly sought-after public speaker. They are both on vivid display in this highly readable and entertaining autobiography, which begins with his childhood in the Bronx and embraces his long and distinguished career.” -- Michael Rosbash, Ph.D., Peter Gruber Professor of Neuroscience, Brandeis University, Investigator of the Howard Hughes Medical Institute“Lefkowitz is not only a gifted scientist, but also a gifted story-teller. From the Yankees to Duke basketball to the game show Jeopardy through the upper echelons of science on his way to a Nobel Prize, he proves that science can be fun and rewarding for himself, the field, and his patients." -- Brian Druker, M.D., Director, Knight Cancer Institute, Oregon Health & Science University“Lefkowitz appreciates the power of storytelling, both at the bedside in making diagnoses and at the bench in generating hypotheses. Full of vignettes that are sometimes embarrassingly honest, at other times laugh-out-loud humorous, but always infused with his own special brew of humility and hubris. An informative and entertaining read.” -- Helen H. Hobbs, Investigator, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center“A tribute to teamwork that aims to inspire the young generation of scientists to take a similar journey. This book shows that making a breakthrough discovery, changing a paradigm, and using science as a tool to change people’s lives is possible, while also emphasizing that such achievements are not made by angels but by human beings like all of us.” -- Aaron Ciechanover, M.D., D.Sc., Technion, Israel Institute of Technology, Nobel Prize in Chemistry (2004)

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Book Synopsis'Hugely entertaining' Guardian'Fascinating' Mail on SundayIn 1882, Jean-Martin Charcot was the premiere physician in Paris, having just established a neurology clinic at the infamous Salpêtrière Hospital, a place that was called a 'grand asylum of human misery'. Assessing the dismal conditions, he quickly upgraded the facilities, and in doing so, revolutionized the treatment of mental illness. Many of Charcot's patients had neurosyphilis (the advanced form of syphilis), a disease of mad poets, novelists, painters, and musicians, and a driving force behind the overflow of patients in Europe's asylums. A sexually transmitted disease, it is known as 'the great imitator' since its symptoms resemble those of almost any biological disease or mental illness. It is also the perfect lens through which to peel back the layers to better understand the brain and the mind. Yet, Charcot's work took a bizarre turn when he brought mesmerism - hypnotism - into his clinic, abandoning his pursuit of the biological basis of illness in favour of the far sexier and theatrical treatment of female 'hysterics', whose symptoms mimic those seen in brain disease, but were elusive in origin. This and a general fear of contagion set the stage for Sigmund Freud, whose seductive theory, Freudian analysis, brought sex and hysteria onto the psychiatrist couch, leaving the brain behind. How The Brain Lost Its Mind tells this rich and compelling story, and raises a host of philosophical and practical questions. Are we any closer to understanding the difference between a sick mind and a sick brain? The real issue remains: where should neurology and psychiatry converge to explore not just the brain, but the nature of the human psyche?Trade ReviewAbsorbing and scholarly... A twin biography of psychiatry and neurology, their study charts this uneasy relationship from marriage to divorce to reconciliation even as fundamental questions about the nature of mental illness remain... Hugely entertaining. * Guardian *A rollicking ride, patient by patient, through the history of two conditions, hysteria and neurosyphilis. * The Times *Central to this book is the ongoing dispute regarding which mental illnesses can be attributed to physical abnormalities within the brain and which originate in the mind, or consciousness. The authors emphasise that in many cases we still cannot be sure... Along the way, their investigations exhume some unforgettable scenes and characters... Fascinating * Mail on Sunday *Rich, compassionate and passionate... Sceptical of the excesses of both psychological and biological reductionism, it is a refreshing call for an intellectual reset and disciplinary rapprochement. -- Anne Harrington * Nature *This aptly titled book picks up where Oliver Sacks left off in examining the behavioral characteristics of neurobehavioral syndromes in an effort to span the gap that has historically separated the twin disciplines of the brain, neurology and psychiatry. * Jeffrey A. Lieberman, author of Shrinks: The Untold Story of Psychiatry *Through tales of eminent physicians and their suffering patients, replete with sex, drugs, and magnetically-induced hypnotism, we learn how a bacterium that deprived countless souls of their reason also helped scientists discover a role for brain biology in mental illness. * Alan Jasanoff, PhD, author of The Biological Mind *Ropper and Burrell have written an insightful, fantastically readable analysis of what was once called "hysteria." Also, by studying how things can go wrong, we learn a great deal about the working of the human mind when things go right. * Elizabeth Loftus, author of Eyewitness Testimony *Table of Contents0: INTRODUCTION 1: A CLINICAL LESSON 2: WHAT IS A DISEASE? 3: PYGMALION AND GALATEA 4: THE INVENTION OF HYSTERIA 5: THE PAPUAN IDOL 6: HEARTS OF DARKNESS 7: THE SOUL OF A NEW DISEASE 8: THE UNSETTLED TERRITORIES OF THE MIND 9: THE DIFFICULT CASE OF ANNA O. 10: THE DEVIL AND ADRIAN LEVERKÜHN 11: SEX AND THE NEW WOMAN 12: WINNING THE BATTLE AND LOSING THE WAR 13: THE PSYCHIC INTERPRETATION OF DISEASE 14: A BEAUTIFUL NAME FOR A HORRIBLE DISEASE 15: MEDICINAL LOBOTOMY: THE INVENTION OF THORAZINE 16: THE FEVERED DREAM OF A SCIENTIFIC PSYCHOLOGY 17: THE LESSONS OF NEUROSYPHILIS

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Book SynopsisRealistic patient cases to help sharpen clinical decision-making skillsThe 60 cases in Case Files Pediatrics feature realistic clinical scenarios designed to help you enhance and hone your clinical decision-making skills. Each case includes an easy-to-understand discussion correlated to key concepts, definitions of key terms, clinical pearls, and Board-style review questions to reinforce learning. The format allows you to review a patient vignette and then explore/examine the case in a contextual, application-based manner. The book is ideal for both quick-access and slow and careful study.Table of ContentsSection I - How to Approach Clinical ProblemsPart 1. Approach to the PatientPart 2. Approach to Clinical Problem SolvingPart 3. Approach to ReadingSection II - Listing of CasesListing by Case NumberListing by Disorder (Alphabetical)Section III - Clinical CasesSixty Case ScenariosSection IV - Review Questions

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Book SynopsisRealistic patient cases to help sharpen clinical decision-making skillsA Doody's Core Title for 2022! The 60 cases in Case Files Obstetrics & Gynecology feature realistic clinical scenarios designed to help you enhance and hone your clinical decision-making skills. Each case includes an easy-to-understand discussion correlated to key concepts, definitions of key terms, clinical pearls, and Board-style review questions to reinforce learning. The format allows you to review a patient vignette and then explore/examine the case in a contextual, application-based manner. The book is ideal for both quick-access and slow and careful study.Table of ContentsSection I - How to Approach Clinical ProblemsPart 1. Approach to the PatientPart 2. Approach to Clinical Problem SolvingPart 3. Approach to ReadingPart 4. Approach to SurgerySection II - Listing of CasesObstetric TopicsGynecologic TopicsSection III - Review Questions

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Book SynopsisImagine learning to tap into the awareness, sensitivity, and highest thought patterns that enable the most successful outcomes in life, love, and business. What would your life look like if you were able to break the patterns of inconsistency that keep you from your absolute best? Could it be possible to identify and regularly access the highest version of yourself, leaving behind past hit-or-miss cycles and instead starting to win in every key area of your life?These goals are not only possible--they are what you were made for!In Balance, bestselling author Touré Roberts guides us on the eye-opening journey that unpacks the divine formula that makes this a reality.This illuminating guide brings a unique and eye-opening perspective to the evasive concept of balance. Transcending familiar theories of work-life balance, Roberts teaches that balance is a state of existence, a becoming that, when realized, not only brings forth the highest version of

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Book Synopsis***This paperback edition has a new introduction by the author and updated content.This is the first volume of North Atlantic Books’ updated paperback edition of Dale Pendell’s Pharmako trilogy, an encyclopedic study of the history and uses of psychoactive plants and related synthetics first published between 1995 and 2005. The books form an interrelated suite of works that provide the reader with a unique, reliable, and often personal immersion in this medically, culturally, and spiritually fascinating subject. All three books are beautifully designed and illustrated, and are written with unparalleled authority, erudition, playfulness, and range. Pharmako/Poeia: Plant Powers, Poisons, and Herbcraft includes a new introduction by the author and as in previous editions focuses on familiar psychoactive plant-derived substances and related synthetics, ranging from the licit (tobacco, alcohol) to the illicit (cannabis, opium) and the exotic (absinthe, salvia divinorum, nitrous oxide). Each substance is explored in detail, not only with information on its history, pharmacology, preparation, and cultural and esoteric correspondences, but also the subtleties of each plant’s effect on consciousness in a way that only poets can do. The whole concoction is sprinkled with abundant quotations from famous writers, creating a literary brew as intoxicating as its subject.The Pharmako series is continued in Pharmako/Dynamis (focusing on stimulants and empathogens) and Pharmako/Gnosis (which addresses psychedelics and shamanic plants).

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Book SynopsisComplications in Equine Surgery is the first reference to focus exclusively on understanding, preventing, recognizing, managing, and prognosing, technical and post-procedural complications in equine surgery. Edited by two noted experts on the topic, the book presents evidence-based information using a clear approach, organized by body system. Featuring color images, the book contains detailed coverage of the gastrointestinal, respiratory, musculoskeletal, urogenital, and neurological systems. Each chapter contains a short introduction of the procedure with explanations of when and how the procedure is to be performed. All chapters review how to recognize and prevent technical complications and explain how to manage post-operative complications. This important text: Offers the first resource specifically focused on complications encountered in equine surgeryTakes a helpful format organized by body systemProvides consistently formatted chapters for ease of useCovers clinically relevanTable of ContentsForeword xi Preface xiii Acknowledgements xv List of Contributors xvi 1 Surgical Complications 1Luis M. Rubio-Martinez and Dean A. Hendrickson 2 Complications of Parenteral Administration of Drugs 10Julie E. Dechant 3 Complications of Intravascular Injection and Catheterization 16Julie E. Dechant 4 Complications of Endoscopy 25Julie E. Dechant 5 Complications of Nasogastric Intubation 29Julie E. Dechant 6 Complications of Fluid Therapy 36Angelika Schoster and Henry Stämpfli 7 Complications Associated with Hemorrhage 57Margaret C. Mudge 8 Complications of Blood Transfusion 64Margaret C. Mudge 9 Complications Associated with Sutures 70Ian F. Devick and Dean A. Hendrickson 10 Complications of Bone Graft Harvesting, Handling, and Implantation 79Lynn Pezzanite and Laurie R. Goodrich 11 Complications of Cryosurgery 87Ann Martens 12 Complications of Laser Surgery 95Kenneth E. Sullins 13 Complications of Systemic Analgesic Drugs 109Maria Amengual-Vila and Eva Rioja Garcia 14 Complications of Loco-Regional Anesthesia 118Eva Rioja Garcia 15 Complications of Sedative and Anesthesia Medications 135Rachel C. Hector and Khursheed Mama 16 Complications During Recovery from General Anesthesia 154Alexander Valverde 17 Complications Associated with Surgical Site Infections 168Denis Verwilghen and J. Scott Weese 18 Complications of Reconstructive Surgery 196Jacintha M. Wilmink and Debra C. Archer 19 Complications of Excessive Granulation Tissue 204Jacintha M. Wilmink and Debra C. Archer 20 Complications of Skin Neoplasia 212Debra Archer and Jacintha M. Wilmink 21 Complications of Skin Grafting 222Debra C. Archer and Jacintha M. Wilmink 22 Complications of Oral and Salivary Gland Surgery 233Patrick Martin Dixon and Richard J.M. Reardon 23 Complications of Esophageal Surgery 254Louise L. Southwood 24 Complications of Stomach Surgery 265Louise L. Southwood 25 Complications of Splenic Surgery 272Eileen Sullivan Hackett 26 Complications of Abdominal Approaches 279Shauna P. Lawless and Eileen Sullivan Hackett 27 Complications of the Intraoperative Colic Patient 291Anje G. Bauck and David E. Freeman 28 Complications of the Postoperative Colic Patient 310Louise L. Southwood 29 Complications of Surgery of the Rectum and Anus 374Michael A. Spirito 30 Complications of Abdominal Surgery: Incisional Hernia 378John P. Caron 31 Complications of Equine Laparoscopy 391Donna L. Shettko and Dean A. Hendrickson 32 Complications of Endoscopic Laser Surgery 404Jan F. Hawkins 33 Complications Following Surgery of the Equine Nasal Passages and Paranasal Sinuses 413Lynn Pezzanite and Jeremiah T. Easley 34 Complications of Pharynx Surgery 427Norm G. Ducharme and Fabrice Rossignol 35 Complications of Larynx Surgery 438Fabrice Rossignol and Norm G. Ducharme 36 Complications of Surgery for Diseases of the Guttural Pouch 468Anje G. Bauck and David E. Freeman 37 Complications of Equine Tracheal Surgery 488John Peroni 38 Complications of Equine Thoracic Surgery 491John Peroni 39 Complications of Testicular Surgery 498James Schumacher and Thomas O’Brien 40 Complications of Penile and Preputial Surgery 522James Schumacher and Thomas O’Brien 41 Complications of Ovarian and Uterine Surgery 532James Schumacher and Thomas O’Brien 42 Complications of Vulvar, Vestibular, Vaginal, and Cervical Surgery 550James Schumacher and Thomas O’Brien 43 Complications of Urinary Surgery 571Sara K.T. Steward and Luis M. Rubio-Martinez 44 Complications of Diagnostic Tests for Lameness 583Ellen R. Singer 45 Complications of Synovial Endoscopic Surgery (Arthroscopy, Tenoscopy, Bursoscopy) 601Troy N. Trumble and Michael C. Maher 46 Complications of Equine Orthopedic Surgery 629Kyla F. Ortved and Dean W. Richardson 47 Complications of Surgery of the Equine Foot 667Britta S. Leise 48 Complications of Surgical Correction of Angular Limb Deformities 683Robert Hunt and Amy M. Buck 49 Complications of Surgical Correction of Flexural Limb Deformities 694Belinda Black and James R. Vasey 50 Complications of Splint Bone Fractures 718Timothy Lescun 51 Complications of Craniomaxillary and Mandible Fractures 730Timothy Lescun 52 Complications of Tendon Surgery 739Roger K.W. Smith 53 Complications of Muscle Surgery 757Brad Nelson 54 Complications of Regenerative Medicine 769Ashlee E. Watts 55 Complications of Osseous Cyst-Like Lesions 774Ashlee E. Watts 56 Complications of Equine Ophthalmic Surgery 779Kate S. Freeman and Dennis E. Brooks 57 Complications of Diagnostic Procedures of the Nervous System 815Laura Johnstone 58 Complications of Anterior Cervical Fusion 826Barrie DonLeo Grant 59 Complications of Surgery for Impingement of Dorsal Spinous Processes 833Luis M. Rubio-Martinez 60 Complications of Peripheral Nerve Surgery 843Yvonne A. Elce Index 855

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Book SynopsisClinically oriented and student-friendly, Basic Clinical Neuroscience provides the anatomic and pathophysiologic basis necessary to understand neurologic abnormalities. This concise but comprehensive text emphasizes the localization of specific medically important anatomic structures and clinically important pathways, using anatomy-enhancing illustrations. Updated throughout to reflect recent advances in the field, the Third Edition features new clinical boxes, over 100 additional review questions, and striking full color artwork.Features Include: Clinical Connection boxes Review questions at the end of each chapter and detailed answers in the back of the book An entire chapter on locating lesions An atlas of myelin-stained sections Unique, hand-drawn, full color artwork A glossary of key terms

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Book SynopsisDeveloping a cybernetic model of subjectivity and personhood that honors disability experiences to reconceptualize the category of the human Twentieth-century neuroscience fixed the brain as the basis of consciousness, the self, identity, individuality, even life itself, obscuring the fundamental relationships between bodies and the worlds that they inhabit. In Unraveling, Matthew J. Wolf-Meyer draws on narratives of family and individual experiences with neurological disorders, paired with texts by neuroscientists and psychiatrists, to decenter the brain and expose the ableist biases in the dominant thinking about personhood. Unraveling articulates a novel cybernetic theory of subjectivity in which the nervous system is connected to the world it inhabits rather than being walled off inside the body, moving beyond neuroscientific, symbolic, and materialist approaches to the self to focus instead on such concepts as animation, modularity, and facilitation. It does so through close readings of memoirs by individuals who lost their hearing or developed trauma-induced aphasia, as well as family members of people diagnosed as autistic—texts that rethink modes of subjectivity through experiences with communication, caregiving, and the demands of everyday life. Arguing for a radical antinormative bioethics, Unraveling shifts the discourse on neurological disorders from such value-laden concepts as “quality of life” to develop an inclusive model of personhood that honors disability experiences and reconceptualizes the category of the human in all of its social, technological, and environmental contexts.Trade Review"Unraveling is a work of cultural reimagination. Matthew J. Wolf-Meyer knits together neurological, psychiatric, and neuroscientific theories about ‘the brain’ in this broad-based inquiry into ‘communicative disorders.’ He insists that the many possibilities and blocked channels of communication depend on the interdependency of subject, personhood, family, community, and polity. He joins leading scholars in disability studies and feminist theory, illuminating the thoroughly social nature of all embodied communication and thus its ethical and political reliance on making a world where differences are welcome."—Rayna Rapp, New York University"This is a book for our times—a deep dive into the problematics of personhood in relationship to the neurological. This book, alluringly readable, vigorously challenges our conceptions of what makes a human being human and advocates for an anti-neoliberal vision of complex selfhood that is not dependent on predictable norms. While this subject could lend itself to predictable advocacy, Matthew J. Wolf-Meyer stays ahead of the reader's assumptions and provides a new and thoughtful way of conceiving big questions concerning the very definitions of life, thought, value, and ethics. A must read for anyone interested in neurodivergence and disability in general."—Lennard J. Davis, author of Obsession: A HistoryTable of ContentsContentsPreface: Blind-Man-and-WorldIntroduction: Let’s Build a New Nervous System1. Neurological Subjectivity: How Neuroscience Makes and Unmakes People through Neurological Disorder2. Symbolic Subjectivity: How Psychoanalysis and the Communication of Meaning Disable Individuals3. Materialist Subjectivity: How Technology and Material Environments Make Personhood Possible4. Cybernetic Subjectivity: The Fusion of Body, Symbol, and Environment in the Facilitated Person5. Facilitated Subjectivity, Affective Bioethics, and the Nervous SystemEpilogue: Living and Dying in the Nervous System AcknowledgmentsNotesIndex

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Book SynopsisConnect to the magic of the world around you for healing, empowerment and self-careNature is filled with hidden, elusive energies: the growth spirals of sunflowers, the electromagnetic spectrum of rainbows, the bio-energy of trees and the sound waves of thunder. Working with the potent energy of nature''s bounty, you will learn to nurture and embrace your inner guardian witch through spell work.Brimming with rituals, wishes and enchantments to encourage spiritual growth, abundance and prosperity, and featuring beautiful illustrations from the author, this book is an illuminating guide to harnessing the earth''s power for personal reflection. It reveals how magic can be used as a reciprocal force for good that protects and promotes our well-being, as well as that of our planet.The Little Book of Earth Magic is for those who seek to form a meaningful connection with nature and take their spiritual practice to a new level.

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Book SynopsisBuilding on the previous edition with contributions from internationally renowned experts this book provides a fully comprehensive resource for managing the post emergency/treatment stage of acute poisoning. Chapters incorporate evidence-based paradigms with up-to-date citations from the original medical literature. Topic areas covered include: diagnosis and management of the critically poisoned patient, including pediatric patients and poisoning in pregnancy; toxic syndromes including hepatotoxic and pulmonary syndromes as well as poisonings from medications, drugs of abuse, chemical and biological agents. This book is an essential resource for Clinical Toxicologists, Intensivists and Emergency Medicine specialists in training and in practice.Trade Review“This is a valuable addition to the archives of clinical toxicology and will undoubtedly become the standard for the profession. … I highly recommend this book as a necessary addition to the professional library of every medical student and resident with an interest in clinical toxicology as well as practitioners at all levels (nurses, fellows, residents, and attending level physicians) of critical care, intensive care, emergency medicine, and clinical and medical toxicology.” (Michael I. Greenberg, Clinical Toxicology, Vol. 56 (3), December, 2017)Table of Contents4-Dimethylaminophenol.- Acetaminophen (Paracetamol).- Beta Receptor Antagonists.- Cardiac Conduction and Rate Disturbances.- Digitalis Glycosides.- Extracorporeal Membrane Oxygenation and Cardiopulmonary Bypass in the Poisoned Patient.- Fumigants.- Gyromitra Mushrooms.- Hydrocarbons and Halogenated Hydrocarbons.- Irritant and Toxic Respiratory Injuries.- Lipid Resuscitation Therapy.- Marine Vertebrates, Cnidarians and Mollusks.- Nerve Agents.- Organophosphorus and Carbamate Insecticides.- Phosphine and Metal Phosphide.- Rifampin, Dapsone, and Vancomycin.- Salicylates.- Thallium.- Unithiol (DMPS).- Valproic Acid.- Widow and Related Lactrodectus Spiders.

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Book SynopsisHEALTHY EATING WITHOUT ANY OF THE HASSLE. The Batch Lady's simple, freezable, portion-controlled recipes will save you time and money.By following the revolutionary guidance of Sunday Times best-selling author The Batch Lady, you too can take control of your diet and create fresh and satisfying meals without spending hours in the kitchen.With over 100 amazingly simple, healthy, home-cooked recipes that can easily be stored in the freezer, The Batch Lady Healthy Family Favourites will ensure that you are sticking to your goals and not reaching for a takeaway or ready meal when you're short on time. And with Suzanne's signature easy-to-follow recipe combinations enabling you to create two or more delicious breakfasts, quick lunches, and weeknight meals simultaneously that the whole family are guaranteed to enjoy, this book will help transform your kitchen and ensure that you live a healthier, happier life, without any of the stress.

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Book SynopsisEvidence-Based Orthopedics is an up-to-date review of the best evidence for the diagnosis, management, and treatment of orthopedic conditions. Covering orthopedic surgery as well as pre- and post-operative complications, this comprehensive guide provides recommendations for implementing evidence-based practice in the clinical setting. Chapters written by leading clinicians and researchers in the field are supported by tables of evidence that summarize systematic reviews and randomized controlled trials. In areas where evidence is insufficient to recommend a practice, summaries of the available research are provided to assist in decision-making. This fully revised new edition reflects the most recent evidence using the approved evidence-based medicine (EBM) guidelines and methodology. The text now places greater emphasis on GRADEa transparent framework for developing and presenting summaries of?evidenceto allow readers to easily evaluate the quality of evidence and the Table of ContentsContributors xv Foreword xxix Preface xxxi Abbreviations xxxiii Section I Methodology of Evidence-Based Orthopedics 1 Principles of Evidence-Based Orthopedics 3 Niek Van Der Hoek MD and Paul Tornetta III MD 2 Hierarchy of Evidence and Common Study Designs 7 Annie George BHSc, Ydo V. Kleinlugtenbelt MD PhD, and Kim Madden PhD 3 Systematic Reviews and Meta-Analyses 11 Joseph T. Patterson MD and Saam Morshed MD PhD MPH 4 Healthcare Recommendations: Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) Approach 19 Mark Phillips BSc PhD, Cand 5 Outcomes and Their Interpretations 25 Leah Gitajn MD 6 Value-Based Orthopedics 31 Nathan N. O’Hara MHA and Daniel Mwayafu MBChB MMed Section II Orthopedic Medicine 7 Critical Issues in Osteoporosis Management 39 Matthew Wong-Pack BHSc MD (Cand), Kyra Cummings, Arthur Lau MD FRCPC, and Jonathan D. Adachi MD FRCPC 8 Venous Thromboembolic Events 51 Ernest Kwek MBBS FRCS(Ed) and Richard E. Buckley MD FRCSC 9 Blood Transfusion 55 Seper Ekhtiari MD MSc, David W. Sanders MD FRCSC, and Jeffrey L. Carson MD 10 Wound Infections 59 Mark D. Hasenauer MD, Michael D. Hunter MD, Kyle J. Jeray MD, and Atul F. Kamath MD 11 Smoking Cessation 65 Paul E. Matuszewski MD, David Zuelzer MD, and Robert V. O’Toole MD 12 Perioperative Medical Management 71 Jennifer Muniak MD, Susan M. Friedman MD MPH, Joseph A. Nicholas MD MPH, and Daniel A. Mendelson MD MSc 13 Orthobiologics 75 John A. Buza III MD and Thomas A. Einhorn MD 14 Intimate Partner Violence 83 Sheila Sprague PhD, Taryn Scott MSW, Erika Arseneau MSc, Prism Schneider MD FRCSC, Andrew Furey MD FRCSC, Rudolf Poolman MD PhD, Emil Schemitsch MD, and Mohit Bhandari MD PhD 15 Pain Management in Orthopedic Surgery 91 Vishal Uppal MD FRCA and Harsha Shanthanna MD PhD 16 Post-Traumatic Stress Disorder and Depression 99 Basem Attum MD and William Obremsky 17 Nutrition and Supplements in Orthopedic Care, 105 Martí Bernaus MD, Brad Petrisor MD MSc, Sofia Bzovsky MSc, and Sheila Sprague PhD Section III Joint Reconstruction III.I Hip and Knee 18 Outpatient Total Joint Arthroplasty 113 Michael Pollock BSc MSc and Brent Lanting MD 19 Hip Preservation 117 Ahmed El-Bakoury MBBS PhD, Asif A. H. Parkar MBBS, and James N. Powell MD 20 The Direct Anterior Approach 123 Thomas J. Wood MD and Brent Lanting MD MSc 21 Computer Navigation in Total Hip Arthroplasty 129 Aamer Malik MD PhD and Lawrence Dorr MD 22 Highly Crosslinked Polyethylene in Total Hip Arthroplasty 135 Glen Richardson MD MSc FRCSC and Michael J. Dunbar MD PhD FRCSC 23 Hip Resurfacing 141 Adam Hart MD MASc, Nikolaos Davarinos MD MSc, and John Antoniou MD PhD 24 Metal-on-Metal Hip Arthroplasty 147 Oliver Marin-Peña MD, Olga Pidgaiska MD, and Pedro Reis-Campos 25 Ceramic in Total Hip Arthroplasty 153 Peter M. Lewis MB BCh FRCS(Orth) and James P. Waddell MD FRCSC 26 Cement in Total Hip Arthroplasty 161 Jorge H. Nuñez MD, Tony Fraguas MD, Ernesto Guerra-Farfán MD, and Diego Collado MD 27 Head Size in Total Hip Arthroplasty 167 Francesc Angles MD, Jorge H. Nuñez MD, and Pablo Castillón MD 28 Dual Mobility in Total Hip Arthroplasty 173 Iñaki Mimendia MD, Maria Jurado MD, Ernesto Guerra-Farfán MD, and Victor BarroMDPhD 29 Trunnionosis 179 Christopher Del Balso MBBS MSc, Emil Schemitsch MD, and Brent Lanting MD MSc 30 Periprosthetic Hip Fractures 185 Lisa C. Howard MD, Bas A. Masri MD, Don S. Garbuz MD, and Clive P. Duncan MD 31 The Infected Total Hip Arthroplasty 191 Sebastián A. León MD, Xin Y. Mei MD, and Paul R. Kuzyk MD MASc 32 The Painful Total Hip Arthroplasty 199 Asif A. H. Parkar MBBS, Ahmed El-Bakoury MBBS PhD, and James N. Powell MD 33 Revision of the Femoral Component 205 Lisa C. Howard MD, Bas A. Masri MD, Don S. Garbuz MD, and Clive P. Duncan MD 34 Revision of the Acetabular Component 213 Nikolaos Davarinos MD MSc, Adam Hart MDCM MASc, and John Antoniou MD PhD 35 Antibiotic Cement in Total Knee Arthroplasty 221 Stephen M. Petis MD MSc FRCSC and Steven J. MacDonald MD FRCSC 36 Unicompartmental Knee Arthroplasty and Patellofemoral Resurfacing Arthroplasty 225 Waleed Albishi MBBS, Paul Jamieson MD, Ivan Kamikovski MD, and Geoffrey Dervin MD 37 Cemented versus Uncemented Fixation in Total Knee Arthroplasty 231 Thomas Turgeon MD FRCSC 38 Cruciate Retaining versus Posterior Stabilized Total Knee Arthroplasty 237 Michael G. Zywiel MD MSc FRCSC and Sarah Ward MD MLA FRCSC 39 Patellar Resurfacing in Total Knee Arthroplasty 243 Michael G. Zywiel MD MSc FRCSC, Rajiv Gandhi MD MSc FRCSC, and Nizar N. Mahomed MD ScD FRCSC 40 Mechanical versus Kinematic Alignment in Total Knee Arthroplasty 249 Pascal-André Vendittoli MD MSc, William Blakeney MBBS MSc MS FRACS, Charles Rivière, and Gene Dossett 41 Ligament Balancing in Total Knee Arthroplasty 253 Pascal-André Vendittoli MD MSc, Jihad Matta MD, Christophe Fornasieri MD, and William Blakeney MBBS MSc MS FRACS 42 Robotics in Total Knee Arthroplasty 259 Seper Ekhtiari MD MSc, Vickas Khanna MD, and Anthony Adili MD 43 Patient-Specific Instrumentation in Total Knee Arthroplasty 265 Seper Ekhtiari MD MSc, Luc Rubinger MD, Vickas Khanna MD, and Anthony Adili MD 44 Metal Allergy in Total Knee Arthroplasty 269 Evangelos Tyrpenou MD, Amit Atrey MD MSc FRCSC 45 Perioperative Management in Total Knee Arthroplasty 275 Sebastian M. Klim MD and Mathias Glehr MD 46 Arthrofibrosis following Total Knee Arthroplasty 279 Samuel T. Walters MBBS, Saket Tibrewal MBBS, and Jakob van Oldenrijk MD PhD 47 High-Flexion Implants in Total Knee Arthroplasty 285 Thomas J. Wood MD FRCSC and Douglas D. R. Naudie MD FRCSC 48 Venous Thromboembolism in Total Knee Arthroplasty 289 Harman Chaudhry MD MSc and Mitch Winemaker MD FRCSC 49 Highly Cross-Linked Polyethylene in Total Knee Arthroplasty 295 Pascal-André Vendittoli MD MSc, William Blakeney MBBS MSc MS FRACS, Ebru Oral, and Orhun Muratoglu 50 Exposure and Implant Options in Revision Total Knee Arthroplasty 301 Felipe Moreira MD, Maria Jurado MD, and Marcelo Casaccia MD 51 The Painful Total Knee Arthroplasty 307 Jason Werle MD FRCSC, Kelly Johnston MD FRCSC, Nicholas Desy MD FRCSC, and Stuart Goodman MD PhD FRCSC 52 Diagnosing the Infected Total Knee Arthroplasty 315 Mina Tohidi MD and John F. Rudan MD 53 Management of the Infected Total Knee Arthroplasty 321 Ewout S. Veltman MD and Dirk Jan F. Moojen MD PhD 54 Management of the Unstable Total Knee Arthroplasty 325 John Esposito MD FRCSC and James L. Howard MD MSc FRCSC 55 Stem Choices in Revision Total Knee Arthroplasty 329 Pablo A. I. Slullitel MD, Gerard M. J. March MD FRCSC, and Paul R. Kim MD FRCSC 56 Periprosthetic Fractures: Knee 335 Jesse Wolfstadt MD MSc FRCSC and Aaron Nauth MD MSc FRCSC 57 Femoral Bone Defects in Revision Total Knee Arthroplasty 341 Adam Katchky MD MSc FRCSC and David J. Backstein MEd MD FRCSC 58 Management of Structural Defects in Revision Knee Arthroplasty: Tibial Side 349 Sebastián León MD, Jennifer Leighton MD FRCSC, Xin Y. Mei MD, and Paul R. Kuzyk MD MASc FRCSC 59 Patellar Options in Revision Total Knee Arthroplasty 355 Jesse Wolfstadt MD MSc FRCSC and Paul Zalzal MASc MD FRCSC III.II Shoulder 60 Implant Design Options in the Treatment of Shoulder Osteoarthritis 361 Chad Myeroff MD, Michael Knudsen MD, and Michael D.McKee MD FRCS(C) 61 Cement in Shoulder Arthroplasty 369 Midhat Patel MD and Niloofar Dehghan MD FRCSC 62 Management of Glenoid Bone Loss 375 Diego Soza MD, Montserrat García-Portabella MD, Lledó Batalla MD, and Josep Massons MD PhD 63 Reverse Total Shoulder Arthroplasty 381 Mitchel D. Armstrong MD BMSc FRCSC, Bandar M. Assiry MBBS SB-orth, and Ryan T. Bicknell MD MSc FRCSC 64 Glenoid Components in Total Shoulder Arthroplasty 387 Eric Benson MD, George Athwal MD, and Kenneth Faber MD 65 Periprosthetic Joint Infection in Shoulder Arthroplasty 393 Peter Lapner MD FRCSC, Jay Keener MD, and Thomas Duquin MD III.III Foot and Ankle 66 Ankle Osteoarthritis 401 Rosa Busquets MD PhD and Andrea Sallent MD 67 Osteoarthritis of the 1st Metatarsophalangeal Joint 407 Seper Ekhtiari MD MSc and Waleed Kishta MD PhD 68 Hallux Valgus 413 Sebastián Drago Perez MD and Cristian Ortiz Mateluna MD 69 Cavovarus Foot 419 Sebastián Drago Perez MD and Cristian Ortiz Mateluna MD Section IV Trauma IV.I General Trauma 70 Damage Control Orthopedics 425 Sascha Halvachizadeh MD, Paolo Cinelli PhD, Florin Allemann MD, Philipp Kobbe MD MHBA, and Hans-Christoph Pap MD 71 Open Fractures 431 Michael D. Hunter MD, Mark D. Hasenauer MD, Atul F. Kamath MD, and Kyle J. Jeray MD 72 The Mangled Extremity 437 Tiffany Huynh MD and Ted V. Tufescu MD FRCSC 73 Acute Compartment Syndrome 441 Aurelia Bihari PhD, Christopher Del Balso MBBS MSc FRCSC, and Abdel-Rahman Lawend MD PhD FRCSC 74 Noninvasive Technologies for Fracture Repair 447 Natsumi Saka MD, Yoshinobu Watanabe MD PhD, and Takashi Matsushita MD DSc 75 Calcium-Based Bone Substitutes 451 Ross Leighton BSc MD FRCSC, Kelly Trask BEng MSc CCRP, Thomas A. Russell MD, Mohit Bhandari MD MSc, and Richard E. Buckley MD FRCSC IV.II Shoulder Girdle and Upper Extremity 76 Scapula Fractures 457 Peter A. Cole MD and Lisa K. Schroder BS MBA 77 Sternoclavicular Joint 463 Annie Weber MD and Raymond A. Pensy MD 78 Clavicle Fractures 469 Chad Myeroff MD and Michael D.McKee MD FRCS(C) 79 Acromioclavicular Joint 475 Chad Myeroff MD and Michael D. McKee MD FRCS (C) 80 Proximal Humeral Fractures 481 Benjamin Kopp MD and David Ring MD PhD 81 Humeral Shaft Fractures 487 David J. Hak MD MBA FACS and Cyril Mauffrey MD FRCS FACS 82 Distal Humerus Fractures 491 Brandon Girardi MD, Emil H. Schemitsch MD, and Aaron Nauth MD MSc 83 Elbow Dislocations 499 Lisa C. Howard MD and Jason W. Pollock MD 84 Radial Head Fractures 505 James D. Spearman Jr MD MBA, David Ring MD PhD, and Lee M. Reichel MD 85 Olecranon Fractures 509 Michael C. Daly MD and Jesse B. Jupiter MD 86 Forearm Fractures 515 Habeeb Khan CCPA and Rudolf W. Poolman MD PhD 87 Distal Radius Fractures 521 Boris A. Zelle MD and Riikkaa E. Nomides MD 88 Carpal Dislocations 525 Carl Nunziato MD, Geert A. Buijze MD PhD, and David Ring MD PhD 89 Carpal Fractures 529 Bert Perey MD FRCSC, Emanuelle Villemaire-Côté MD FRCSC, and Francesc A. Marcano-Fernández MD PhD 90 Metacarpal Fractures 537 Christina Ward MD IV.III Pelvis and Lower Extremity 91 Pelvic Fractures 541 G. Yves Laflamme MD FRCS(c), Jonah Hébert-Davies MD FRCS(c)c, and Dominique M.Rouleau MD MSc FRCS(c) 92 Acetabular Fractures 547 Juan Antonio Porcel Vázquez MD and Ernesto Guerra-Farfán 93 Hip Dislocations 553 Luis Felipe López MD, Carlos Prada MD MHSc, Brett D. Crist MD FACS, and Gregory J. Della Rocca MD PhD Facs 94 Femoral Head Fractures 559 Kevin D. Phelps MD, Joshua L. Gary MD, and Milton Lee “Chip” Routt Jr MD 95 Femoral Neck Fractures in Younger Patients 565 Malynda Wynn MD, Trevor Gulbrandsen MD, Michael Willey MD, and Matthew Hogue MD 96 Femoral Neck Fractures in the Elderly 571 Dylan McCreary BA, Brian P. Cunningham MD, and Marc Swiontkowski MD 97 Extracapsular Hip Fractures 577 Luke A. Lopas MD, Andrew F. Tyler MD PhD, and Samir Mehta MD 98 Subtrochanteric Femur Fractures 583 John Morellato BSc (Pharm) MBBS (Hons) FRCSC, Steven Papp BSc MSc MD FRCSC, Wade Gofton BSc MSc MD FRCSC, and Allan Liew BSc MD FRCSC 99 Femoral Shaft Fractures 589 Costas Papakostidis MD and Peter V. Giannoudis MD Facs Frcs 100 Distal Femur Fractures 595 Graeme Hoit MD, Amir Khoshbin MD, and Rudolf W. Poolman MD PhD 101 Proximal Tibia Fractures 601 Daniel Axelrod MD, Richard Jenkinson MD MSc FRCSC, and Hans Kreder MD MPH FRCSC 102 Tibial Shaft Fractures 607 Taylor Yong MD MS, Ilda Molloy MD MS, and Leah Gitajn MD 103 Intra-Articular Distal Tibia (Pilon/Plafond) Fractures 613 Luc Rubinger MD, Seper Ekhtiari MD MSc, and Peter J. O’Brien MD 104 Malleolar Fractures 619 Daniel Axelrod MD and David W. Sanders MD FRCSC 105 Talus Fractures 625 Pablo Mery MD and Carlos Prada MD MHSc 106 Calcaneal Fractures 631 Richard E. Buckley MD FRCSC 107 Lisfranc Injuries 637 Robin R. Elliot MA FRCS, Nicholas B. Jorgensen MBBS, and Terrence S. Saxby MBBS FRACS 108 Fifth Metatarsal Fractures 643 Robin R. Elliot MA FRCS, Nicholas B. Jorgensen MBBS, and Terrence S. Saxby MBBS FRACS Section V Spine 109 Mechanical Neck Pain 651 Kenneth Nwosu MD and Thomas Cha MD MBA 110 Whiplash 655 Eren O. Kuris MD and Alan H. Daniels MD 111 Cervical Radiculopathy and Myelopathy 659 Michael Fehlings MD PhD FACS FRCSC and Jetan Badhiwala MD 112 Mechanical Low Back Pain: Operative Management 665 Pranay Patel MD, Ian Buchanan MD, Zorica Buser PhD, and Jeffrey C. Wang MD 113 Mechanical Low Back Pain: Nonoperative Management 671 Kirkham Wood MD and Craig McMains MD 114 Neurogenic Claudication 677 Gregor Lønne MD PhD and Øystein Nygaard MD 115 Lumbar Radiculopathy 683 Daniel G. Tobert MD and James D. Kang MD 116 Adolescent and Adult Spinal Deformity: Nonoperative Management 687 Patrick Thornley MD and Colby Oitment MD FRCSC 117 Adolescent and Adult Spinal Deformity: Operative Management 693 Peter G. Passias MD, Frank A. Segreto MD, Samantha R. Horn BA, and Cole A. Bortz BA 118 Metastatic/Myeloma Disease 699 Marco Ferrone MD and Justin Bulcher MSc 119 Spinal Infections 705 Stuart D. Kinsella MD MTR, Lauren B. Barton BS, and Andrew J. Schoenfeld MD MSc Section VI Sports Medicine VI.I General 120 Ergogenic Aids 713 Michael J. O’Brien MD VI.II Shoulder 121 First Time Shoulder Dislocation 717 Dane Swinehart MD, Jordan Meiss MD, and Charles Cox MD 122 Recurrent Shoulder Instability 723 Joost I. P. Willems MD, Amber von Gerhardt MD, W. Jaap Willems MD, and Arthur van Noort MD PhD 123 Rotator Cuff Tears 729 Alberto Blanco MD, Montserrat García-Portabella MD, Lledó Batalla MD, and Josep Massons MD 124 Massive and Irreparable Rotator Cuff Tears 735 Brandon J. Erickson MD and Joshua S. Dines MD 125 Subacromial Pain Syndrome 739 Egbert J. D. Veen MD and Ron L. Diercks MD 126 Pathology of the Long Head of the Biceps 743 Daniel Wang BA, David Ring MD PhD, and Matt Driscoll MD 127 Superior Labral Tears and Throwing Shoulder Injuries 749 Michael T. Freehill MD, Jacob M. Kirsch MD, Hiroyuki Sugaya MD, and Jon J. P. Warner MD VI.III Elbow 128 Ulnar Collateral Ligament Injuries of the Elbow 755 Frank G. J. Loeffen MD, Izaäk F. Kodde MD PhD, and Denise Eygendaal MD PhD 129 Lateral Epicondylitis (Tennis Elbow) 761 Neeru Jayanthi MD 130 Osteochondritis Dissecans Lesions of the Elbow 769 Matthew Smith MD and Mitchel Obey MD VI.IV Hip 131 Labral Tears 775 Chetan Gohal MD, Nolan S. Horner MD, and Marc R. Safran MD 132 Femoroacetabular Impingement 779 Marc J. Philippon MD, Ioanna K. Bolia MD, and Karen K. Briggs MPH VI.V Knee 133 Initial Management of the Sports Injured Knee 783 Marc Aguilar Garcia MD, Carla Carbonell Rosell MD, and Joan Pijoan Bueno MD 134 Meniscal Tears 787 Nicola Maffulli MD MS PhD FRCS (Orth), Domiziano Tarantino MD, and Rocco Aicale MD 135 Anterior Cruciate Ligament Injuries 793 Aaron Gazendam MD, Darren de SA MD, and Freddie Fu MD 136 Posterior Cruciate Ligament Injuries 799 Chetan Gohal MD, Nolan S. Horner MD, Jihad Abouali MD, and John Theodoropoulos MD MSc 137 Combined Anterior Cruciate Ligament and Medial Collateral Ligament Injuries 805 Domiziano Tarantino MD, Rocco Aicale MD, and NicolaMaffulli MD MS PhD FRCS (Orth) 138 Multiligamentous Knee Injuries 811 James P. Stannard MD and Hee Young Lee MD 139 Posterolateral Corner Injuries 815 Nolan S. Horner MD, Chetan Gohal MD, Olufemi R. Ayeni MD PhD, and Daniel B. Whelan MD MSc 140 Lateral Extra-Articular Tenodesis Procedures and the Anterolateral Ligament 819 Felipe Moreira MD, Merce Reverté MD PhD, Enric Castellet MD, and Joan Minguell MD PhD 141 Cartilage Lesions of the Knee 825 Mario Hevesi MD, Aaron J. Krych MD, and Daniël B. F. Saris MD PhD 142 Patellofemoral Pain Syndrome (Runner’s Knee) 831 Carlos Prada MD MHSc and Sebastián Irarrázaval MD 143 Osteotomy and Lower Extremity Realignment Procedures 837 Jayson Lian BA, Darren de SA MD, João V. Novaretti MD, and Volker Musahl MD VI.VI Foot & Ankle 144 Ankle Ligament Injuries 843 Gwendolyn Vuurberg PhD, J. Nienke Altink BSc, Rover Krips MD PhD, and Gino M. M. J. Kerkhoffs MD PhD 145 Achilles Tendinopathy 849 Domiziano Tarantino MD, Rocco Aicale MD, and Nicola Maffulli MD MS PhD FRCS (Orth) Section VII Wrist 146 Distal Radius Malunions 855 Muhanned Ali MD, Roberto S. Rosales MD PhD, and Isam Atroshi MD PhD 147 Distal Radial–Ulnar Joint 861 Nina Suh MD 148 Wrist Osteoarthritis 867 Randy Bindra MD 149 Rheumatoid Wrist Reconstruction 873 Warren Hammert DDS MD 150 Acute Scaphoid Fractures 877 Joseph J. Dias MD (Research) FRCS MBBS 151 Scaphoid Nonunions 883 Anne Eva J. Bulstra MD, Job N. Doornberg MD PhD, Myriam C. Obdeijn MD PhD, and Geert A. Buijze MD PhD 152 Carpal Instability 889 Jessica B. Hawken MD and Aviram M. Giladi MD MS 153 Kienböck’s Disease 895 Simon B. M. MacLean and Gregory I. Bain 154 Trapeziometacarpal Osteoarthritis 899 Jeremiah D. Johnson MD, Jennifer M. Brewer BA, and Jennifer Moriatis Wolf MD Section VIII Hand 155 Carpal Tunnel Syndrome: Nonoperative Management 907 Thomas A. Miller MD FRCPC, Christopher Doherty MD MPH FRCSC, and Douglas C. Ross MD MEd FRCSC 156 Carpal Tunnel Syndrome: Operative Management 913 Douglas C. Ross MD MEd FRCSC, Christopher Doherty MD MPH FRCSC, and Thomas A. Miller MD FRCPC 157 Carpal Tunnel Release: Minor Procedure Room or Operating Room? 917 Kevin Cheung MD and Hannah St Denis-Katz MD 158 Thumb Carpometacarpal Osteoarthritis 921 Ryan Wolek MD, Steven McCabe MD MSc, and Matthew Furey MD MSc 159 Flexor Tendon Injuries: Surgical Management 925 Robert M. Szabo MD MPH and Shima Sokol MD 160 Flexor Tendon Injuries: Rehabilitation 931 Matthew McRae MD, Mark McRae MD, Daniel Waltho MD, and Jenny Santos MSc 161 Extensor Tendon Injuries 935 Noor Alolabi MD, Monica Alderson MSc, and Carolyn M. Levis MD MSc 162 Dupuytren’s Disease 947 Lauren Willoughby BMSc MD FRCSC, Daniel Waltho MD, Marta Karpinski BHSc, and Achilleas Thoma MD MSc 163 Rheumatoid Hand Reconstruction 953 Kevin C. Chung MD MS, Oluseyi Aliu MD, and Sandra V. Kotsis MPH 164 Replantation 957 Serge Goekjian MD FRCS (C), Lucas Gallo BHSc MD (c), and Achilleas Thoma MD MSc 165 Ulnar Neuropathy 963 Christopher Doherty MD MPH FRCSC, Thomas A. Miller MD FRCPC, and Douglas C. Ross MD MEd FRCSC 166 Finger Fractures 969 Claire Ryan MD and David Ring MD PhD Section IX Oncology 167 Radiation Therapy in Soft Tissue Sarcoma 975 Anthony Bozzo MD MSc, Aaron Gazendam MD, and Kurt R. Weiss MD 168 Chemotherapy in Soft Tissue Sarcoma 981 Robert J. Wilson ii MD, Jennifer L. Halpern MD, Jill Gilbert MD, Ginger E. Holt MD, Vicki L. Keedy MD, and Herbert S. Schwartz MD 169 Surgical Margins in Soft Tissue Sarcoma 993 Eugenia Schwarzkopf MD, Tomohiro Fujiwara MD, and John H. Healey MD 170 Allograft versus Megaprosthesis 999 Kelly C. Homlar MD, Robert J. Wilson ii MD, Jessica Rose Wilson MD MSCI, Jennifer L. Halpern MD, Herbert S. Schwartz MD, and Ginger E. Holt MD 171 Biopsy of Soft Tissue Masses 1005 Aaron Gazendam MD, Anthony Bozzo MD MSc, Casey Wang MD, and David Wilson MD MASc 172 Denosumab in Giant Cell Tumors of Bone 1011 Michael Parry MD and Robert Grimer MD Section X Pediatrics 174 Cerebral Palsy 1029 Vedant Kulkarni MD 175 Pediatric Osteoarticular Infections 1035 Brice Ilharreborde MD, Cindy Mallet MD, and Dimitri Ceroni MD 176 Simple Bone Cysts 1041 Cristina Alves MD FEBOT, Inês Balacó MD, Marta Salom Taverner MD PhD, Thomas Wirth MD PhD, and Michiel Van De Sande MD PhD 177 Pediatric Clavicle Fractures 1047 Benton E. Heyworth MD and Nirav Pandya MD 178 Supracondylar Humerus Fractures 1053 Ravi Brar MD MPH, David Skaggs MD MMM, and Sanjeev Sabharwal MD MPH 179 Adolescent Spondylolisthesis 1061 Matthew E. Oetgen MD MBA and M. Timothy Hresko MD 180 Early Onset Scoliosis 1067 Jason Pui Yin Cheung MBBS MMedSc MS FHKAM (orth) FRCS(orth) FHKCOS(Edin), Susan Nelson MD MPH, James O. Sanders MD, and Ron El-Hawary MD MSc FRCS (C) 181 Developmental Dysplasia of the Hip 1075 Emily K. Schaeffer PhD and Wudbhav N. Sankar MD 182 Legg–Calvé–Perthes Disease 1081 Benjamin Joseph MS Orth MCh Orth FRCS Ed and Hitesh Shah MS Orth 183 Slipped Capital Femoral Epiphysis 1087 Eduardo Novais MD and Randy Loder MD 184 Pediatric Femoral Shaft Fractures 1093 Matthew Winterton MD, Shital Parikh MD FACS, and Keith Baldwin MD MSPT MPH 185 Infantile Blount Disease 1099 Steven M. Rivero MD and Sanjeev Sabharwal MD MPH 186 Pediatric Anterior Cruciate Ligament Injuries 1107 Lindsay Schlichte MS, Colleen Wixted BS, and Daniel Green MD MS FACS 187 Clubfoot 1113 Anna D. Vergun MD and Peter Moskal MD 188 Tarsal Coalitions 1119 Joseph Fox MD and Maryse Bouchard MD MSc 173 Outcomes in Pediatric Orthopedics 1019 Unni G. Narayanan MBBS MSc FRCS(C) Index, 1125

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Book SynopsisTable of ContentsForeword xix Acknowledgments xxi Abbreviations xxiii Book Navigation xxix Part I Understanding Cell Culture 1 1. Introduction 3 1.1 Terminology 3 1.2 Historical Development 4 1.3 Applications 12 1.4 Advantages of Tissue Culture 13 1.5 Limitations of Tissue Culture 15 References 18 2. Biology of Cultured Cells 23 2.1 The Culture Environment 23 2.2 Cell Adhesion 23 2.3 Cell Division 28 2.4 Cell Fate 30 2.5 Cell Death 35 References 36 3. Origin and Evolution of Cultured Cells 39 3.1 Origin of Cultured Cells 39 3.2 Evolution of Cell Lines 40 3.3 Changes in Genotype 43 3.4 Changes in Phenotype 46 3.5 Senescence and Immortalization 48 Minireview M3.1 Senescence and Immortalization 48 3.6 Transformation 50 3.7 Conclusions: Origin and Evolution 58 References 58 Part II Laboratory and Regulatory Requirements 63 4. Laboratory Design and Layout 65 4.1 Design Requirements 65 4.2 Layout of Laboratory Areas 74 4.3 Disaster and Contingency Planning 80 References 83 5. Equipment and Materials 85 5.1 Sterile Handling Area Equipment 85 5.2 Imaging and Analysis Equipment 97 5.3 Incubation Equipment 99 5.4 Preparation and Washup Equipment 104 5.5 Cold Storage Equipment 107 References 109 6. Safety and Bioethics 111 6.1 Laboratory Safety 111 6.2 Hazards in Tissue Culture Laboratories 117 6.3 Biosafety 121 6.4 Bioethics 129 References 132 7. Reproducibility and Good Cell Culture Practice 137 7.1 Reproducibility 137 7.2 Good Practice Requirements 141 7.3 Cell Line Provenance 145 7.4 Validation Testing 146 7.5 Quality Assurance (QA) 148 7.6 Replicate Sampling 150 References 151 Part III Medium and Substrate Requirements 155 8. Culture Vessels and Substrates 157 8.1 Attachment and Growth Requirements 157 8.2 Substrate Materials 158 8.3 Substrate Treatments 159 8.4 Feeder Layers 163 8.5 Choice of Culture Vessel 164 8.6 Application-Specific Vessels 170 References 173 9. Defined Media and Supplements 177 9.1 Medium Development 177 9.2 Physicochemical Properties 177 9.3 Balanced Salt Solutions 185 9.4 Media Formulations 186 9.5 Serum 189 9.6 Other Media Supplements 191 9.7 Choice of Complete Medium 191 9.8 Storage of Medium and Serum 194 Suppliers 194 References 194 10. Serum-Free Media 199 10.1 Rationale for Serum-Free Medium 199 10.2 Development of Serum-Free Medium 201 10.3 Serum-Free Media Formulations 202 10.4 Serum-Free Supplements 203 10.5 Serum Replacements 209 10.6 Use of Serum-Free Medium 209 10.7 Xeno-Free Media 213 10.8 Animal Product-Free Media 214 10.9 Conclusions: Serum-Free Media 214 Suppliers 214 References 215 11. Preparation and Sterilization 219 11.1 Terminology: Preparation 219 11.2 Sterilization Methods 220 11.3 Glassware 224 Protocol P11.1 Preparation and Sterilization of Glassware 224 11.4 Other Laboratory Apparatus 229 11.5 Water 229 11.6 Media and Other Reagents 233 11.7 Sterile Filtration 238 11.8 Medium Testing 242 Suppliers 247 References 247 Part IV Handling Cultures 249 12. Aseptic Technique 251 12.1 Objectives of Aseptic Technique 251 12.2 Elements of Aseptic Environment 252 12.3 Sterile Handling 258 12.4 Good Aseptic Technique 260 12.5 Controlling Equipment Contamination 265 Suppliers 267 References 267 13. Primary Culture 269 13.1 Rationale for Primary Culture 269 13.2 Initiation of Primary Culture 270 13.3 Tissue Acquisition and Isolation 274 13.4 Primary Explantation 281 Protocol P13.3 Culture of Primary Explants 281 13.5 Enzymatic Disaggregation 283 13.6 Mechanical Disaggregation 290 Protocol P13.7 Mechanical Disaggregation by Sieving 291 13.7 Enrichment of Viable Cells 292 Protocol P13.8 Enrichment of Viable Cells 292 13.8 Record Keeping for Primary Culture 293 13.9 Conclusions: Primary Culture 294 Suppliers 294 References 294 14. Subculture and Cell Lines 297 14.1 Terminology: Cell Line and Subculture 297 14.2 Initiating a Cell Line 298 14.3 Choosing a Cell Line 300 14.4 Maintaining a Cell Line 304 14.5 Replacing Medium (Feeding) 309 14.6 Subculture (Passaging) 312 14.7 Maintaining Suspension Cultures 320 14.8 Serum-Free Subculture 322 14.9 Record Keeping for Cell Lines 323 Suppliers 324 References 325 15. Cryopreservation and Banking 327 15.1 Principles of Cryopreservation 327 15.2 Apparatus for Cryopreservation 329 15.3 Requirements for Cryopreservation 335 15.4 Cryopreservation Procedures 336 15.5 Cell Banking Procedures 341 15.6 Cell Repositories 342 15.7 Record Keeping for Frozen Stocks 345 15.8 Transporting Cells 347 Suppliers 348 References 348 Part V Validation and Characterization 351 16. Microbial Contamination 353 16.1 Sources of Contamination 353 16.2 Management of Contamination 359 Protocol P16.1 Disposal of Contaminated Cultures 360 16.3 Visible Microbial Contamination 361 16.4 Mycoplasma Contamination 364 16.5 Viral Contamination 373 16.6 Dealing with Persistent Contamination 376 Suppliers 376 References 376 17. Cell Line Misidentification and Authentication 381 17.1 Terminology: Cross-Contamination, Misidentification, and Authentication 381 17.2 Misidentified Cell Lines 382 17.3 Cell Line Authentication 386 17.4 Authentication of Challenging Samples 401 17.5 Conclusions: Authentication 403 Suppliers 403 References 403 18. Cell Line Characterization 409 18.1 Priorities and Essential Characterization 409 18.2 Genotype-Based Characterization 416 18.3 Phenotype-Based Characterization 419 18.4 Cell Imaging 423 18.5 Cell Staining 428 Suppliers 430 References 430 19. Quantitation and Growth Kinetics 437 19.1 Cell Counting 437 19.3 Cell Proliferation 450 19.4 Cloning Efficiency 456 19.5 DNA Synthesis 460 19.6 Cell Cycle Analysis 461 Suppliers 461 References 461 Part VI Physical and Genetic Manipulation 465 20. Cell Cloning and Selection 467 20.1 Terminology: Cloning and Selection 467 20.2 Cloning by Limiting Dilution 468 20.3 Cloning in Suspension 473 20.4 Selection of Clones 477 20.5 Replica Plating 480 20.6 Stimulation of Cloning Efficiency 481 20.7 Selective Culture Conditions 485 20.8 Conclusions: Cloning and Selection 487 Suppliers 487 References 487 21. Cell Separation and Sorting 491 21.1 Cell Density and Isopycnic Centrifugation 491 21.2 Cell Size and Sedimentation Velocity 495 21.3 Magnetic Separation and Sorting 496 Protocol P21.2 Magnet-Activated Cell Sorting (MACS) 499 21.4 Fluorescence-Activated Cell Sorting (FACS) 500 21.5 Microfluidic Sorting 502 Minireview M21.1 Microfluidic Cell Culture 503 21.6 Conclusions: Sorting and Separation 505 Suppliers 505 References 505 22. Genetic Modification and Immortalization 509 22.1 Gene Delivery 509 22.2 Gene Editing 517 22.3 Immortalization 523 22.4 Screening and Artifacts 526 Suppliers 528 References 528 Part VII Stem Cells and Differentiated Cells 535 23. Culture of Stem Cells 537 23.1 Terminology: Stem Cells 537 23.2 Embryonic Stem Cells (ESCs) 540 23.3 Induction of Pluripotency 545 Protocol P23.1 Generation of iPSCs Using Sendai Viral Vectors 547 23.4 Human Pluripotent Stem Cell (hPSC) Lines 549 23.5 Perinatal Stem Cells 556 23.6 Adult Stem Cells 557 23.7 Stem Cell Characterization and Banking 558 23.8 Conclusions: Culture of Stem Cells 560 Suppliers 561 References 561 24. Culture of Specific Cell Types 567 24.1 Specialized Cells and Their Availability 567 24.2 Epithelial Cells 572 24.3 Mesenchymal Cells 577 24.4 Neuroectodermal Cells 580 24.5 Hematopoietic Cells 581 24.6 Culture of Cells from Poikilotherms 585 Suppliers 587 References 587 25. Culture of Tumor Cells 593 25.1 Challenges of Tumor Cell Culture 593 25.2 Primary Culture of Tumor Cells 594 25.3 Development of Tumor Cell Lines 596 25.4 Selective Culture of Tumor Cells 599 25.5 Specific Tumor Types 603 25.6 Cancer Stem Cells (CSCs) 606 Minireview M25.1 Culture of Cancer Stem Cells 606 Suppliers 608 References 608 26. Differentiation 615 26.1 In Vitro Models of Differentiation 615 26.2 Differentiation Status in Culture 617 26.3 Induction of Differentiation 620 26.4 Practical Aspects 628 26.5 Ongoing Challenges 629 Suppliers 631 References 631 Part VIII Model Environments and Applications 639 27. Three-Dimensional Culture 641 27.1 Terminology: 3D Culture 641 27.2 Technologies for 3D Culture 643 Minireview M27.1 Advances in Technologies Enabling 3D Cell Culture and the Formation of Tissue-Like Architecture In Vitro 643 27.3 Benefits and Limitations of 3D Culture 646 27.4 Scaffold-Free 3D Culture Systems 647 27.5 Scaffold-Based 3D Culture Systems 652 27.6 Organoid Culture 659 27.7 Organotypic Culture 660 27.8 Organ Culture 662 27.9 Characterization of 3D Cultures 662 Suppliers 663 References 663 28. Scale-Up and Automation 669 28.1 Terminology: Scale-Up and Bioreactors 669 28.2 Scale-Up in Suspension 671 28.3 Scale-Up in Monolayer 677 28.4 Monitoring and Process Control 685 28.5 Scale-Up for Manufacture 688 Minireview M28.1 Culture Scale-Up and Bioreactors 688 28.6 High-Throughput Screening 691 28.7 Automation and Bioprinting 691 Suppliers 696 References 696 29. Toxicity Testing 701 29.1 In Vitro Toxicity Testing 701 29.2 Cytotoxicity Assays 704 29.3 Genotoxicity Assays 715 29.4 Carcinogenicity Assays 716 29.5 Advanced Models for Toxicity Testing 716 Suppliers 719 References 719 Part IX Teaching and Troubleshooting 725 30. Training 727 30.1 Training Principles 727 30.2 Training Programs 729 References 731 31. Problem Solving 733 31.1 Microbial Contamination 733 31.2 Cross-Contamination and Misidentification 737 31.3 Chemical Contamination 738 31.4 Slow Cell Growth 738 31.5 Abnormal Cell Appearance 740 31.6 Problems with Materials 741 31.7 Problems with Primary Culture 744 31.8 Problems with Feeding or Subculture 746 31.9 Problems with Cryopreservation 748 31.10 Problems with Cloning 750 References 752 32. In Conclusion 753 Appendix A Glossary 755 Appendix B Calculations and Preparation of Reagents 761 Calculations 761 Counting Cells with a Hemocytometer 761 Dilution of a Cell Suspension 761 Population Doubling Level (PDL) 761 Molarity 762 Percentages and Dilutions 762 Pressure 762 Rotor Speed (rpm to g) 762 Preparation of Reagents 762 Acetic Acid: Methanol 762 Agar (2.5%) 762 Alcohol (70%) 762 Bacto™ Peptone (5%) 763 Balanced Salt Solutions 763 Carboxymethylcellulose (CMC; 4%) 763 Chick Embryo Extract 763 Collagenase 763 Collection Medium 763 Crystal Violet (0.1%) 764 Dexamethasone (1 mg/ml) 764 Dissection Balanced Salt Solution (DBSS) 764 Dulbecco’s Phosphate-Buffered Saline Without Ca2+ and Mg2+ (DPBS-A) 764 EDTA (10 mM in DPBS-A) 764 EGTA 764 Erythrosin B 764 Gelatin (1%) 765 Giemsa Stain 765 Glucose (20%) 765 Glutamine 200 mM 765 Hanks’s Balanced Salt Solution (HBSS) 765 HAT Medium 765 HB Medium 765 HEPES 765 Hoechst 33258 766 Media 766 2-Mercaptoethanol (𝛽-Mercaptoethanol; 0.1 M) 766 Methylcellulose (Methocel, 1.6%) 766 Mitomycin C (100 μg/ml) 766 MTT (50 mg/ml) 766 N2 Supplement 766 N2B27 Medium 767 Naphthalene Black (Amido Black; 1%) 767 Non-essential Amino Acids (NEAA, 100×) 767 Paraformaldehyde (4%) 767 Trypan Blue (0.4%) 767 Trypsin (2.5%) 768 Versene 768 Suppliers 768 References 768 Appendix C Media Formulations 769 References 779 Index 781

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Book Synopsis"Synthesizing across disciplines--Attachment, Polyvagal, Neuroscience, Child Development Theory, Trauma, and Somatics--this book provides a new lens through which to understand safety and regulation. For therapists working with both adults and children and anyone dealing with symptoms that typically arise from early childhood trauma--anxiety, behavioral issues, depression, metabolic disorders, migraine, sleep problems, and more--this book offers fresh hope"--

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Book SynopsisTable of ContentsPart I: INTRODUCTION. 1. Substance Abuse Counseling for Today. 2. Drugs and Their Effects. 3. Motivational Interviewing. Part II: THE PROCESS OF BEHAVIOR CHANGE. 4. Assessment and Treatment Planning. 5. Helping Clients Change. 6. Empowering Clients Through Group Work. 7. Maintaining Change in Substance Use Behaviors. Part III: THE CONTEXT OF CHANGE. 8. Working with Families. 9. Successful Service Programs. 10. Preventing Substance Abuse. APPENDICES. A. Psychosocial and Substance Use History. B. Initial Behavioral Assessment and Functional Analysis. C. Comprehensive Drinker Profile. D. Family Drinking Survey. E. Useful Websites. F. Valuable Treatment Manuals.

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Book SynopsisSheds light on the surprisingly diverse and shared visions for realizing Israel as a democratic Jewish state. Building on Arthur Hertzberg's classic, The Zionist Idea, Gil Troy explores the backstories, dreams, and legacies of more than 170 passionate Jewish visionaries from the 1800s to today.Trade Review"The Zionist Ideas: Visions for the Jewish Homeland–Then, Now, Tomorrow . . . takes a comprehensive approach to unpacking the challenges modern Zionism faces, while simultaneously expanding on the virtues of Jewish self-determination."—Daniel J. Roth, Jerusalem Post"Troy has done an extraordinary job in explaining the Zionist ideas that co-exist within Jewish life. As the subtitle puts it, this book explains the Zionism of the past, the debates going on in the present, and the visions of the future that occupy the minds and hearts of Zionists. Like Hertzberg's original book, it explains and it inspires."—Jack Riemer, Jewish Advocate"Troy has delivered an anthology that will give us plenty to argue about for years to come."—Elliot Jager, Jerusalem Report"Even within our relatively small community, we too often speak to only those who agree with us. No one is better positioned to change this reality than Natan Sharansky, the universally beloved hero of the Jewish people, and Gil Troy, an academic respected equally in Israel and North America, and whose book The Zionist Ideas should be standard fare at every synagogue, JCC, and day school, and given as a gift to every b'nai mitzvah."—Eric Fingerhut, Times of Israel Blog"An excellent cross-section of Zionist thought, ideology and popular culture as well, and a worthy update of Hertzberg's masterpiece. . . . Troy's volume will help us make sense of an increasingly chaotic Zionist world."—Jerome A. Chanes, New York Jewish Week"Reading this is like being on a tour of Zionist thought that Troy is leading us through as he analyzes Zionism's evolution from its early ideology as a national movement to its development of its own."—Reviews by Amos Lassen"The Zionist Ideas is an important update and essential addition to every Jewish studies library. The wealth of ideas found between its pages gives the reader an extraordinary opportunity to explore how his or her own thinking can fit into the spectrum of Zionist thought. Troy's update has revitalized Hertzberg's groundbreaking work and opened a new opportunity for conversation about Zionism and the central place of Israel in Jewish life."—Jonathan Fass, Jewish Book Council"Building on Arthur Hertzberg's classic, The Zionist Idea, Troy explores the backstories, dreams, and legacies of more than 170 passionate Jewish visionaries from the 1800s to today."—Algemeiner"At its core, Troy's anthology is an invitation to readers to consider what it means to be a Zionist, especially in the 21st century."—Jay P. Lefkowitz, Commentary"Instead of replacing Hertzberg, Troy's book will sit neatly on the shelf next to the original. Together, they are the essential primary sources for understanding the complex foundations of Israel and its meaning in the 21st century. Students will be reaching for both of them for a long time to come."—nealgold.netTable of ContentsContents Foreword by Natan Sharansky Acknowledgments Introduction: How Zionism’s Six Traditional Schools of Thought Shape Today’s Conversation Part One. Pioneers: Founding the Jewish State 1. Pioneers: Political Zionism Peretz Smolenskin It Is Time to Plant (1875–77) Let Us Search Our Ways (1881) The Haskalah of Berlin (1883) Leon Pinsker Auto-Emancipation: An Appeal to His People by a Russian Jew (1882) Theodor Herzl The Jewish State (1896) From the Diaries of Theodor Herzl (1895) Third Letter to Baron Hirsch (1895) Max Nordau Zionism (1902) Muskeljudentum, Jewry of Muscle (1903) Jacob Klatzkin Boundaries: Judaism Is Nationalism (1914–21) Chaim Weizmann On the Report of the Palestine Commission (1937) Natan Alterman Shir Moledet (Song of the homeland) (1935) Magash HaKesef (The silver platter) (1947) Albert Einstein Palestine, Setting of Sacred History of the Jewish Race (with Erich Kahler) (1944) 2. Pioneers: Labor Zionism Moses Hess Rome and Jerusalem (1862) bilu bilu Manifesto (1882) Joseph Hayyim Brenner Self-Criticism (1914) Nahman Syrkin The Jewish Problem and the Socialist Jewish State (1898) Ber Borochov Our Platform (1906) Aaron David Gordon People and Labor (1911) Our Tasks Ahead (1920) Rachel Bluwstein My Country (1926) Berl Katzenelson Revolution and Tradition (1934) Rahel Yanait Ben-Zvi The Plough Woman (1931) 3. Pioneers: Revisionist Zionism The Union of Zionists-Revisionists Declaration of the Central Committee of the Union of Zionists-Revisionists (1925) Vladimir Jabotinsky The Fundamentals of the Betarian World Outlook (1934) Evidence Submitted to the Palestine Royal Commission (1937) The Iron Wall ([1923] 1937) Saul Tchernichovsky I Believe (1892) They Say There’s a Land (1923) The Irgun Proclamation of the Irgun Zvai Leumi (1939) Avraham (Yair) Stern Eighteen Principles of Rebirth (1940) Haim Hazaz The Sermon (1942) 4. Pioneers: Religious Zionism Yehudah Alkalai The Third Redemption (1843) Samuel Mohilever Message to the First Zionist Congress (1897) Isaac Jacob Reines A New Light on Zion (1902) Abraham Isaac Kook The Land of Israel (1910–30) The Rebirth of Israel (1910–30) Lights for Rebirth (1910–30) Moshe “Kalphon” HaCohen Mateh Moshe (Moses’s headquarters) (1920) Meir Bar-Ilan (Berlin) What Kind of Life Should We Create in Eretz Israel? (1922) 5. Pioneers: Cultural Zionism Eliezer Ben-Yehudah A Letter of Ben-Yehudah (1880) Introduction to The Complete Dictionary of Ancient and Modern Hebrew (1908) Ahad Ha’am (Asher Zvi Ginsberg) On Nationalism and Religion (1910) The Jewish State and the Jewish Problem (1897) Hayyim Nahman Bialik The City of Slaughter (1903) At the Inauguration of the Hebrew University (1925) Micah Joseph Berdichevski Wrecking and Building (1900–1903) In Two Directions (1900–1903) On Sanctity (1899) Martin Buber Hebrew Humanism (1942) An Open Letter to Mahatma Gandhi (1939) 6. Pioneers: Diaspora Zionism Solomon Schechter Zionism: A Statement (1906) Louis Dembitz Brandeis The Jewish Problem and How to Solve It (1915) Henrietta Szold Letter to Augusta Rosenwald (1915) Horace Mayer Kallen Zionism and Liberalism (1919) Stephen S. Wise Challenging Years (1949) Milton Steinberg The Creed of an American Zionist (1945) Part Two. Builders: Actualizing and Modernizing the Zionist Blueprints 7. Builders: Political Zionism Israel’s Declaration of Independence (1948) David Ben-Gurion The Imperatives of the Jewish Revolution (1944) Speech to Mapai Central Committee (1948) Am Segula: Memoirs (1970) The Law of Return (1950) Isaiah Berlin Jewish Slavery and Emancipation (1953) The Achievement of Zionism (1975) Abba Eban Statement to the Security Council (1967) Teddy Kollek Jerusalem (1977) Chaim Herzog Address to the United Nations General Assembly (1975) Albert Memmi The Liberation of the Jew (1966, 2013) Jews and Arabs (1975) Yonatan (Yoni) Netanyahu Letters from Yoni Netanyahu (1968, 1975) Elie Wiesel One Generation After (1970) A Jew Today (1975, 1978) Natan Sharanksy Fear No Evil (1988) Emmanuel Levinas Politics After (1979) Assimilation and New Culture (1980) Martin Peretz The God That Did Not Fail (1997) 8. Builders: Labor Zionism Golda Meir A Land of Our Own (1973) Address to the United Nations General Assembly (1958) Muki Tsur The Soldiers’ Chat (1967) Amos Oz The Meaning of Homeland (1967) Roy Belzer Garin HaGolan Anthology (1972) The Members of Kibbutz Ketura The Kibbutz Ketura Vision (1994) Yaakov Rotblit Shir LaShalom, A Song for Peace (1969) Leonard Fein Days of Awe (1982) Yitzhak Rabin Our Tremendous Energies from a State of Siege (1994) Shimon Peres Nobel Lecture (1994) Shulamit Aloni I Cannot Do It Any Other Way (1997) 9. Builders: Revisionist Zionism Uri Zvi Greenberg Those Living-Thanks to Them Say (1948) Israel without the Mount (1948–49) Geulah Cohen Memoirs of a Young Terrorist (1943–48) The Tehiya Party Platform (1988) Moshe Shamir For a Greater Israel (1967) The Green Space: Without Zionism, It’ll Never Happen (1991) Menachem Begin The Revolt (1951) Broadcast to the Nation (1948) Statement to the Knesset upon the Presentation of His Government (1977) Yitzhak Shalev We Shall Not Give Up Our Promised Borders (1963) Eliezer Schweid Israel as a Zionist State (1970) The Promise of the Promised Land (1988) Benjamin Netanyahu A Place among the Nations (1993) 10. Builders: Religious Zionism Ben-Zion Meir Chai Uziel Prayer for the State of Israel (1948) On Nationalism (ca. 1940–50) David Edan A Call for Aliyah (ca. 1950) Joseph Ber Soloveitchik Listen! My Beloved Knocks! (1956) Yeshayahu Leibowitz A Call for the Separation of Religion and State (1959) Zvi Yehuda Hakohen Kook On the 19th Anniversary of Israel’s Independence (1967) Abraham Joshua Heschel Israel: An Echo of Eternity (1969) Esther Jungreis Zionism: A Challenge to Man’s Faith (1977) Talma Alyagon-Roz Eretz Tzvi, The Land of Beauty (1976, 2014) Eliezer Berkovits On Jewish Sovereignty (1973) Gush Emunim Friends of Gush Emunim Newsletter (1978) David Hartman Auschwitz or Sinai (1982) The Third Jewish Commonwealth (1985) Commission on the Philosophy of Conservative Judaism Emet V’Emunah: Statement of Principles of Conservative Judaism (1988) Richard Hirsch Toward a Theology of Reform Zionism (2) Ovadia Yosef Oral Torah 14 (1979) 11. Builders: Cultural Zionism Haim Hefer There Were Times (1948) A. M. Klein The Second Scroll (1951) Leon Uris The Exodus Song / This Land Is Mine (1960) Shmuel Yosef Agnon Nobel Prize Speech (1966) Naomi Shemer Jerusalem of Gold (1967) Yehudah Amichai All the Generations before Me (1968) Tourists  (1980) Gershon Shaked No Other Place (1980, 1987) Letty Cottin Pogrebin Deborah, Golda, and Me (1991) Anne Roiphe Generation without Memory (1981) 12. Builders: Diaspora Zionism Arthur Hertzberg Impasse: A Movement in Search of a Program (1949) Some Reflections on Zionism Today (1977) Mordecai M. Kaplan A New Zionism (1954, 1959) Rose Halprin Speech to the Zionist General Council (1950) Jacob Blaustein Statements by Prime Minister David Ben-Gurion and Mr. Jacob Blaustein on the Relationship between Israel and American Jews (1950, 1956) Simon Rawidowicz Babylon and Jerusalem (1957) Two That Are One (1949) Irving “Yitz” Greenberg Twenty Years Later: The Impact of Israel on American Jewry (1968) Yom Yerushalayim: Jerusalem Day (1988) Eugene Borowitz Twenty Years Later: The Impact of Israel on American Jewry (1968) Herman Wouk This Is My God (1969, 1974) Arnold Jacob Wolf Will Israel Become Zion? (1973) Breira National Platform (1977) Hillel Halkin Letters to an American Jewish Friend: The Case for Life in Israel (1977, 2013) Dennis Prager and Joseph Telushkin Nine Questions People Ask about Judaism (1975) Alex Singer Alex: Building a Life (1983, 1986, 1996) Blu Greenberg What Do American Jews Believe? A Symposium (1996) Part Three. Torchbearers: Reassessing, Redirecting, Reinvigorating 13. Torchbearers: Political Zionism Michael Oren Jews and the Challenge of Sovereignty (2006) Tal Becker Beyond Survival: Aspirational Zionism (2011) Michael Walzer The State of Righteousness: Liberal Zionists Speak Out (2012) Aharon Barak Address to the 34th World Zionist Congress in Jerusalem (2002) Yael “Yuli” Tamir A Jewish and Democratic State (2) Ze’ev Maghen John Lennon and the Jews: A Philosophical Rampage (2010) Daniel Gordis The Promise of Israel (2012) Leon Wieseltier Brothers and Keepers: Black Jews and the Meaning of Zionism (1985) Irwin Cotler Speech to the United Jewish Communities General Assembly (2006) Gadi Taub In Defense of Zionism (2014) Bernard-Henri Lévy The Genius of Judaism (2017) Asa Kasher idf Code of Ethics (1994) 14. Torchbearers: Labor Zionism Anita Shapira The Abandoned Middle Road (2012) Ephraim Katchalski-Katzir My Contributions to Science and Society (2005) Ruth Gavison Statement of Principles, Gavison-Medan Covenant (2003) Einat Wilf Zionism: The Only Way Forward (2012) Chaim Gans The Zionism We Really Want (2013) David Grossman Speech at Rabin Square (2006) Nitzan Horowitz On the Steps of Boorishness (2013) Alon Tal Pollution in a Promised Land (2002, 2017) Peter Beinart The Failure of the American Jewish Establishment (2010) Ari Shavit Back to Liberal Zionism (2014) A Missed Funeral and the True Meaning of Zionism (2013) Stav Shaffir Knesset Speech (2015) 15. Torchbearers: Revisionist Zionism Yoram Hazony The End of Zionism? (1995) Israel’s Jewish State Law and the Future of the Middle East (2014) Shmuel Trigano There Is No “State of All Its Citizens” (2015, 2017) Israel Harel We Are Here to Stay (2001) Caroline Glick The Israeli Solution: A One-State Plan for Peace in the Middle East (2014) Ruth Wisse Jews and Power (2007) David Mamet Bigotry Pins Blame on Jews (2006, 2011) The Secret Knowledge: On the Dismantling of American Culture (2011) Ze’ev B. “Benny” Begin The Essence of the State of Israel (2015, 2017) Reuven Rivlin Remarks of President Rivlin: Vision of the Four Tribes (2015) Ayelet Shaked Pathways to Governance (2016) 16. Torchbearers: Religious Zionism Daniel Polisar Is Iran the Only Model for a Jewish State? (1999) Benjamin Ish-Shalom Jewish Sovereignty: The Challenges of Meaning, Identity, and Responsibility (2014) Eliezer Sadan Religious Zionism: Taking Responsibility in the Worldly Life of the Nation (2008) Yaacov Medan Statement of Principles, Gavison-Medan Covenant (2003) Yehuda Amital Reishit Tzemichat Ge’ulatenu: What Kind of Redemption Does Israel Represent? (2005) Benjamin “Benny” Lau The Challenge of Halakhic Innovation (2010) Yedidia Z. Stern Ani Ma’amin, I Believe (2005) Leah Shakdiel The Reason You Are Here Is Because You Are a Jew! (2004) Arnold Eisen What Does It Mean to Be a Zionist in 2015? Speech to the 37th Zionist Congress: (2015) Conservative Judaism Today and Tomorrow (2015) David Ellenson Reform Zionism Today: A Consideration of First Principles (2014) 17. Torchbearers: Cultural Zionism Gil Troy Why I Am a Zionist (2008) Yair Lapid I Am a Zionist (2009) Micah Goodman From the Secular and the Holy (2018) Ronen Shoval Herzl’s Vision 2.0 (2013) A. B. Yehoshua The Basics of Zionism, Homeland, and Being a Total Jew (2017) Erez Biton Address at the President’s House on the Subject of Jerusalem (2016) Bernard Avishai The Hebrew Republic (2008) Saul Singer They Tried to Kill Us, We Won, Now We’re Changing the World (2011) Sharon Shalom A Meeting of Two Brothers Who Had Been Separated for Two Thousand Years (2017) Einat Ramon Zionism: A Jewish Feminist-Womanist Appreciation (2017) Adam Milstein Israeliness Is the Answer (2016, 2017) Rachel Sharansky Danziger A New Kind of Zionist Hero (2015, 2017) 18. Torchbearers: Diaspora Zionism Jonathan Sacks Will We Have Jewish Grandchildren? (1994) Alan Dershowitz The Vanishing American Jew (1997) Yossi Beilin His Brother’s Keeper: Israel and Diaspora Jewry in the Twenty-First Century (2) Scott Shay Getting Our Groove Back: How to Energize American Jewry (2007) Donniel Hartman Israel and World Jewry: The Need for a New Paradigm (2011) Yossi Klein Halevi A Jewish Centrist Manifesto (2015) Ellen Willis Is There Still a Jewish Question? I’m an Anti-Anti-Zionist (2003) Theodore Sasson The New American Zionism (2013) Central Conference of American Rabbis A Statement of Principles for Reform Judaism (1999) The World Zionist Organization Jerusalem Program (1951) Jerusalem Program (2004) Source Acknowledgments Sources

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Book SynopsisTake control of your health, lose weight, prevent disease, and enjoy a long and healthy life.

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Book SynopsisA top neuroscientist’s science-driven plan on how to take better care of your brain, and, in doing so, how to enhance your memory, lose excess weight, and increase your energy and vitality. Build your best health and life possible by taking care of your brain.Your brain is the most essential organ in your body.  The brain and spinal cord are intimately connected to every bodily system and organ, so when it is balanced everything in your body and mind will function more efficiently.  It’s vitally important to take proactive steps now, or you risk losing everything, including your ability to think clearly, be creative, remember details, solve problems, and retain your memory.In Biohack Your Brain, leading neuroscientist Dr. Kristen Willeumier reveals how you can change your brain by making simple and easy modifications to your lifestyle. Combining clinical experience with revolutionary science, she details how biohacking your brain can boost your cognitive performance and so much more.Dr. Willeumier’s essential guidebook shows you the most effective techniques to prevent memory loss and neurodegenerative disorders like Alzheimer’s disease—and even how to overcome negative thoughts and stress. Through research and case studies, you’ll learn how to upgrade your nutritional choices along with the effective use of supplements, brain games, and physical activity to overcome cognitive damage, whether it’s from previous injuries, such as a concussion or a bad fall, or from the effects of living in modern day times. Dr. Willeumier shares her own story alongside those from the NFL players and other clients she has worked with to help you leverage the latest research to find personal solutions. Biohack Your Brain is a groundbreaking plan for revitalizing, nourishing, and rejuvenating your most essential asset.   Trade Review“After my years playing professional football in the NFL, I took a deep dive into studying the most important organ in my body: the brain. Thankfully, I came across Dr. Willeumier, the foremost expert on research, knowledge, and practical ways to regenerate and revitalize the most valuable asset we each possess. Her passion for and dedication to helping and healing athletes’ brain function is unparalleled, and I am thrilled that you each get to receive some of the wisdom that she has blessed me with over the years.” — EMMANUEL ACHO, former NFL linebacker, Fox Sports analyst, and author of Uncomfortable Conversations with a Black Man “Neurobiologist Willeumier debuts with a collection of proactive, accessible strategies for preserving and promoting cognitive health…This smart take will help those seeking ideas on how to sharpen their mental performance.” — Publishers Weekly “Biohack Your Brain is filled with wisdom, hope, and many great strategies to give you a better brain and a better life. Having worked closely with Dr. Willeumier for more than a decade, I know she is deeply passionate and a great communicator, which is found on every page of this book. I highly recommend it!” — DANIEL AMEN, M.D., CEO and founder of the Amen Clinics and ten-time New York Times bestselling author “I’ve often wished I had a handbook I could give patients that outlined the interventions we actually know can improve brain health. I now have one.” — from the foreword by KEITH L. BLACK, M.D., chair and professor, Department of Neurosurgery, Cedars-Sinai Medical Center “Biohack Your Brain is a superb brain-health guide that will nurture your mind, heart, and spirit.” — BOB ROTH, global meditation leader, CEO of the David Lynch Foundation, and author of the New York Times bestseller Strength in Stillness "It is so easy to get lost in the over-saturated market of mental health and wellness today. I’ve learned as an elite athlete to beware of the quick fix products and tactics promising stronger better brain health with no tangible action steps. Dr. Kristen Willeumier’s Biohack Your Brain is a step-by-step guide to unlock the power of your brain through simplified literal practices anyone can employ to optimize cognitive function. Such a thoughtful, relevant, and necessary approach to improve brain health.” — CHAMIQUE HOLDSCLAW, Team USA Olympic Gold medalist, Hall of Fame athlete, six-time WNBA All-Star, mental health advocate, host of Tremendous Upside podcast “Biohack Your Brain is an essential guide for those who are seeking to upgrade their mental game or to reverse the effects of damage from repetitive impacts. Read the newly revealed secrets Dr. Willeumier has discovered and utilizes—it might just save your brain function.” — LEIGH STEINBERG, J.D., American sports agent, CEO of Steinberg Sports and Entertainment, and author of the New York Times bestseller The Agent "A beneficial overview of the brain, what we know about it, and what we’re still discovering." — Library Journal Advance Reviews "With the rise of health-focused wearables, we're predicting biohacking will be bigger than ever in 2021. This book further fuels that theory, as leading neuroscientist Kristen Willeumier, Ph.D., shares ways to supercharge your brain (think boosting cognitive performance and prevent memory loss) via simple lifestyle changes." — mindbodygreen "In Biohack Your Brain, Kristen Willeumier, PhD, provides simple and easy tips to master cognitive training in your everyday life." — The Women's Alzheimer's Movement Weekly Newsletter “…a manageable guide to live a brain-healthy lifestyle.” — Harper’s Bazaar Arabia

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Book SynopsisThe Birth Space is a doula's guide to conception, pregnancy, birth and postpartum that highlights choice and rights in the perinatal space.In this beautiful book, trained and experienced doula Gabrielle Nancarrow offers comprehensive information about the birthing landscape that will empower you to choose the right birth for you – whether that be an obstetric, midwife or home birth.The Birth Space shows us how to prepare our minds and bodies for pregnancy and labour, from conscious conception through to postpartum and into matrescence. Gabrielle helps us understand what to expect during this period and translates the medical terminology so we are informed. She also provides remedies for common ailments, shares insights from other birth specialists, and is a constant spiritual guide from conception and beyond…talk about continuity of care!Filled with moving photography by Ilsa Wynne-Hoelscher Kidd (@ilsa_whk), Lisa Sorgini @lisa.sorgini, and Hayden Trace (@feelinghomeagain) as well as intimate real-life stories from contributors covering pregnancy loss, IVF, same-sex conception, home births, caesareans and more, The Birth Space is the essential companion for anyone who is seeking guidance as they enter this new chapter of their life‘In The Birth Space … you will find the information and support that will take you from conception through matrescence, with deeper calm, confidence and power.’ Aviva Romm, MD Trade Review'In her new and very thoughtful book, The Birth Space, doula and author Gabrielle Nancarrow renews our appreciation for the magnificence and wonder of the process. From preconception to matrescence, with sensitive storytelling and beautiful photography her words of wisdom bring back normalcy and common sense. The Birth Space fills a large void in the world of pregnancy books and I highly recommend it.' – Stuart J. Fischbein, MD FACOG 'Gabrielle Nancarrow has gathered and shared the wisdom of this pathway, honed by midwives, doulas, and mothers, to which she’s added her own special sauce of lived experience and stories, blended with the latest in innate birthing practices. The result? The Birth Space, in which you will find the information and support that will take you from conception through matrescence, with deeper calm, confidence and power. As a midwife and MD, I welcome you into this sacred space, with joy.' – Aviva Romm, MD, author of The Natural Pregnancy Book, Natural Health After Birth and Botanical Medicine for Women’s Health 'Blending heartfelt storytelling with the wisdom of a doula and a mother, The Birth Space will educate and empower you to own your birth experience and make informed choices that feel right to you. A must-read for all birthing families.' – Abby Epstein and Ricki Lake, filmmakers of The Business of Being Born

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Book SynopsisAndrew Newberg explores the latest findings of neurotheology, the multidisciplinary field linking neuroscience with religious and spiritual phenomena. He investigates some of the most controversial—and potentially transformative—implications of a neurotheological approach.Trade ReviewA tour de force in this emerging field, Neurotheology provides a superb review of the science to date and shows the many directions the field may go in the future. This book raises profound implications for neuroscience, medicine, theology, and philosophy. Fascinating and clearly written and accessible for everyone. Truly mind-blowing. -- Harold Koenig, Duke University Medical CenterThis book offers the promise that ‘neurotheology’ can help move us beyond the conflict between science and religion toward the truth or at least to a more unified and universal perspective on the interface between spirituality and the brain. Neurotheology covers many potential points of contact between science and religion, acknowledges the existence of complexity and the dangers of simple reductionism, and presents clear information on the capabilities and limitations of various forms of neurological assessment. -- John Peteet, Harvard Medical SchoolIn Neurotheology, Andrew Newberg discusses the possibility of a fruitful dialogue between neuroscience and religion and how this sort of investigation may have a profound impact on how we see spirituality, ourselves, and life. A world expert in the neuroimaging study of spiritual experiences, Newberg proposes a nondogmatic approach to the scientific study of spirituality and successfully advocates for fruitful exchanges between science and religion. -- Alexander Moreira-Almeida, Federal University of Juiz de ForaA magnificent work! Newberg is a superb scientist, yet still writes for a curious reader or college student an entirely gripping scholarly account. He addresses some of humanity's all-time epic questions of ultimate meaning with systematic, fine grain research that could only be technically possible in the past decade. A true work of scholarship, with rigor, artful synthesis, and a deep bench of knowledge around spirituality and religion. -- Lisa Miller, Ph.D., Professor and Founder, Spirituality Mind Body Institute, Teachers College, Columbia UniversityThis is an excellent introduction to the emerging field of neurotheology as well as a concise assessment of the contributions of neuroscience to our understanding of a broad range of religious and spiritual issues. * Reading Religion *This volume serves as both a great introduction to the various empirical approaches available to the study of religious phenomena and a strong argument for the crucial role of neurophysiology in aiding the psychology, cognitive science, and anthropology of religion to better understand the ‘why’ and ‘how’ of religious experience and behavior. * Quarterly Review of Biology *This book very usefully highlights complex material related to brain research and neuroscience as applied to areas of human experience broadly categorized as religious. * Religion *[A] comprehensive look at the field of neurotheology, or the neurology of religion. . . . Given that the larger relationship between science and religion has been contested for centuries, Newberg’s latest evidential support for a scientific understanding of why humans practice religion will be a welcome overview for interested readers. * Publishers Weekly *Newberg's book will be of most value to those who are struggling to reconcile science and spirituality. * Choice *Table of ContentsIntroduction: If Neurotheology Is the Answer, What Is the Question?1. Neurotheology and the Happy Prison of the Brain2. What is Neurotheology?3. Neuroscience and Neurotheology4. What is Religion from a Neurotheological Perspective?5. What is Spirituality from a Neurotheological Perspective?6. Neurotheology and the Evolution of Religion7. Neurotheology and Psychology8. Brain Pathology and Religion9. Religious Myths and the Brain10. The Ritualizing Brain11. Religious and Spiritual Practices12. The Spiritual But Not Religious Brain13. Free Will and the Brain14. Escaping the Prison of the Brain: Mysticism15. The End of Faith and the Beginning of NeurotheologyNotesIndex

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Book SynopsisTable of Contents125 chapters organised alphabetically by presenting problem within three sections - Clinical Presentations, Biochemical Presentations and Haematological Presentations.

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Book SynopsisEver since we started huddling together in communities, the story of human history has been inextricably entwined with the story of microbes. They have evolved and spread amongst us, shaping our culture through infection, disease, and pandemic. At the same time, our changing human culture has itself influenced the evolutionary path of microbes. Dorothy H. Crawford here shows that one cannot be truly understood without the other. Beginning with a dramatic account of the SARS pandemic at the start of the 21st century, she takes us back in time to follow the interlinked history of microbes and man, taking an up-to-date look at ancient plagues and epidemics, and identifying key changes in the way humans have lived - such as our move from hunter-gatherer to farmer to city-dweller -- which made us vulnerable to microbe attack. Showing how we live our lives today -- with increasing crowding and air travel -- puts us once again at risk, Crawford asks whether we might ever conquer microbes completely, or whether we need to take a more microbe-centric view of the world. Among the possible answers, one thing becomes clear: that for generations to come, our deadly companions will continue to shape human history.Oxford Landmark Science books are ''must-read'' classics of modern science writing which have crystallized big ideas, and shaped the way we think.Trade ReviewAdmirably clear and engaging. * BBC History *Table of ContentsPreface Introduction 1: How It All Began 2: Our Microbial Inheritance 3: Microbes Jump Species 4: Crowds, Filth, and Poverty 5: Microbes Go Global 6: Famine and Devastation 7: Deadly Companions Revealed 8: The Fight Back Conclusion: Living Together Glossary Notes and References Index

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Book SynopsisThis book presents principles and methods for working with emotion in psychotherapy to address the core maladaptive processes that cause anxiety, depression, and other common clinical disorders.Trade ReviewConceptually brilliant, clinically bold, and empirically persuasive, this book is pure Greenberg—perhaps today’s most well-rounded and accomplished scholar, researcher, practitioner, and trainer in psychotherapy. -- Louis G. Castonguay, PhD, Liberal Arts Professor of Psychology, Penn State University, University Park, PAIn this book, Leslie Greenberg, one of the world’s leading experts, presents a deep and insightful view of how to work with emotion in psychotherapy. This is a book for all practicing therapists, as well as for those who teach psychotherapy and those who do research on psychotherapy. The author presents a unique, research-based model of how working with emotion creates change. I particularly liked the chapters that dealt with therapist skills. It gives a sophisticated and insightful view of the roles of therapist empathy and self disclosure. It also includes important sections on dealing with culture and systemic racism. It will be useful to therapists of all persuasions. I plan to use it in my classes. -- Arthur C. Bohart, PhD, Professor Emeritus, California State University Dominguez HillsLeslie Greenberg has long been a source of some of the most important and generative ideas in our field. At a time when psychotherapy is sometimes reduced to an arid overemphasis on cognition, Greenberg points our attention to experience and emotion. This book is rigorously grounded in research and amply filled with rich nuggets for the clinician. -- Paul L. Wachtel, PhD, Distinguished Professor of Clinical Psychology, City College of CUNY, New York, NYTable of ContentsIntroduction: Working With Emotion in Psychotherapy Part I: Understanding the Fundamentals Chapter 1. Emotion Theory Chapter 2. Research on Emotional Change Chapter 3. Changing Emotion Wth Emotion Chapter 4. Essential Therapist Skills for Practicing Emotion-Based Approaches Part II: Arriving at Emotion Chapter 5. Empathic Attunement to Affect Chapter 6. Focusing on Bodily Feelings: When Words Are Not Enough Chapter 7. Blocks to Emotion Chapter 8. Unblocking Emotion Part III: Leaving Emotion Chapter 9. Working With Needs Chapter 10. Reexperiencing the Past in the Present Chapter 11. Emotion Regulation Chapter 12. Narrative and Emotion Looking Ahead: A Unified Approach to Psychotherapy References About the Author

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Book Synopsis

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