Cardiovascular medicine Books
Jaypee Brothers Medical Publishers Interesting Cases in Hypertension: Useful Lessons
Book SynopsisHypertension is another name for high blood pressure. It can lead to severe complications and increases the risk of heart disease, stroke, and death. Blood pressure is the force exerted by the blood against the walls of the blood vessels. This book presents a selection of clinical case scenarios illustrating diagnostic and management techniques for hypertension. Divided into ten sections, the text begins with discussion on hypertension and associated risk factors, and different types of hypertension. The following sections cover ECGs, diagnosis, and cases of hypertension with comorbidities including pregnancy, renal disorders and vascular conditions. The final section examines secondary hypertension. Each chapter features a clinical case with detailed discussion on diagnosis and management strategies, followed by a selection of questions for self assessment and further learning. Key points Selection of clinical case scenarios for diagnosis and management of hypertension Covers different types of hypertension, including with comorbidities Includes discussion on secondary hypertension Each case features questions for self assessment and further learning Table of Contents1. Hypertension and concomitant risk factors 2. Hypertension – types 3. Interesting ECGs in hypertension 4. Issues in diagnosis 5. Hypertension in pregnancy 6. Hypertension and renal disorders 7. Cerebro vascular associations 8. Secondary hypertension cases 9. Cardiac effects
£24.70
Jaypee Brothers Medical Publishers Advances & Innovations in Heart Failure (AIHF): A
Book SynopsisHeart failure is a serious condition caused by the heart failing to pump enough blood around the body at the right pressure. It usually occurs because the heart muscle has become too weak or stiff to work properly, most commonly caused by heart attack, high blood pressure or cardiomyopathy (heart disease). This textbook is a comprehensive guide to the latest advances in the diagnosis and management of heart failure. Comprising nearly 1000 pages, the book features 15 sections, beginning with discussion on clinical issues of heart failure, followed by imaging techniques. Each of the following sections covers a different disorder or disease that subsequently may lead to heart failure. Topics include coronary artery disease, stroke, arrhythmia, hypertension, nutritional aspects, cardio-oncology, and much more. The book concludes with rehabilitation, legal aspects, and future directions. Authored by internationally recognised experts in the field, the text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to latest advances in diagnosis and management of heart failure Extensive text comprising nearly 1000 pages covering numerous associated disorders and diseases Internationally recognised editor and author team Highly illustrated with clinical photographs, diagrams and tables Table of Contents Section 1: Clinical Section 2: Echo, Imaging and Heart Failure Section 3: Coronary Artery Disease and Heart Failure Section 4: Stroke and Heart Failure Section 5: Arrhythmia and Heart Failure Section 6: Hypertension Section 7: Valvular Section 8: Congenital Heart Disease and Heart Failure Section 9: Metabolic Section 10: Nutritional Section 11: Heart Failure and Cardio-oncology Section 12: Systematics Inflammatory Release Syndrome with Multiorgan Failure and Cardiogenic Shock Section 13: Rehabilitation Section 14: Legal and Ethical Issues Section 15: Future Directions
£114.30
Jaypee Brothers Medical Publishers Manual of Echocardiography
Book SynopsisThis new edition is a comprehensive and practical guide to the use of echocardiography in everyday clinical practice. Divided into thirteen sections, the book begins with the basic principles of echocardiography and echocardiographic examination. Subsequent chapters cover the valves of the heart and vascular system, prosthetic valves, ischemic heart disease, cardiomyopathies, pericardial disorders, cardiac tumours and congenital heart disease. The chapters follow a question and answer format and many are supplemented by case studies, as well as full colour images and illustrations. Much of the content of this manual has been abstracted from Comprehensive Textbook of Echocardiography (9789352701643) published in 2019, also by Navin C Nanda. The second edition has been fully revised and updated to include recent advances in the field. The author and editor team of internationally recognised cardiovascular experts, led by renowned Navin C Nanda, ensures authoritative content throughout the book. Key Points Practical guide to use of echocardiography in everyday clinical practice Fully revised, second edition including recent advances in the field Presented in question and answer format, supplemented by case studies Previous edition (9789351525189) published in 2016 Table of Contents Basics Echocardiographic Examination Mitral Valve Aortic Valve Aortic Diseases Tricuspid and Pulmonary Valves and Pulmonary Hypertension Prosthetic Valves Left Ventricle Ischemic Heart Disease Cardiomyopathies Pericardial Disorders Cardiac Tumours and Masses Congenital Heart Disease
£60.30
Jaypee Brothers Medical Publishers Clinical Diagnosis of Congenital Heart Disease
Book SynopsisClinical Diagnosis of Congenital Heart Disease is the latest edition of this comprehensive, highly illustrated guide to the diagnosis of congenital heart disease. Divided into 31 sections, each chapter discusses a different aspect of congenital heart disease, clearly explaining history, assessment, imaging, clinical diagnosis and management techniques. This third edition has been fully revised to provide the latest advances in the field, with in depth discussion on new diagnostic modalities. Each topic concludes with a summary of key points, and includes schematic diagrams depicting abnormal anatomy and its pathophysiological consequences. Key Points Highly illustrated guide to diagnosis of congenital heart disease Fully revised, third edition with in depth discussion on new diagnostic modalities Each topic features a summary of key points and schematic diagrams of abnormal anatomy Previous edition (9789351529125) published in 2015 Table of Contents Left Ventricular Inflow Obstruction Mitral Valve Prolapse Congenital Mitral Regurgitation Primary Endocardial Fibroelastosis Atrial Septal Defect (Secundum Type) Atrial Septal Defect with Associated Common Anomalies Ventricular septal defect Patent Ductus Arteriosus Aortopulmonary Window Complete Atrioventricular Septal Defect Congenital Aortic Stenosis Coarctation of the Aorta Aneurysms of Sinuses of Valsalva Congenital Coronary Artery Anomalies Aortic Arch Anomalies and Vascular Rings Congenital Pulmonary Stenosis Congenitally Corrected Transposition of Great Arteries Common Atrium Tricuspid Atresia Ebstein’s Anomaly Pulmonary Atresia with Intact Ventricular Septum Tetralogy of Fallot Pulmonary Atresia with Ventricular Sepal Defect Double Outlet Right Ventricle Single Ventricle Truncus Arteriosus Complete Transposition of the Great Arteries Hypoplastic Left Heart Syndrome Total Anomalous Pulmonary Venous Connections Anomalous Systemic Venous Connections Congenital Pulmonary Arteriovenous Fistula
£108.00
Jaypee Brothers Medical Publishers Clinical Cardiology: A Disease Specific Approach
Book SynopsisThis book is a comprehensive guide to the diagnosis and treatment of cardiac diseases, for clinicians and trainees. Divided into 14 sections, each one covers a different type of heart disease and is further subdivided to explain the management of more specific disorders within the same disease group. Complete sections are dedicated to diagnostic investigation and imaging techniques including electrocardiography, chest X-ray, and echocardiography. The text is further enhanced by more than 370 clinical images, flowcharts and tables to assist learning and provide quick reference to key facts. Key points Comprehensive guide to diagnosis and management of cardiac diseases Covers many different types of heart disorder Provides thorough discussion on diagnostic imaging and investigation techniques Highly illustrated with more than 370 clinical images, flowcharts and tables Table of Contents Section A: Rheumatic Heart Disease Section B: Continuous Murmur Section C: Congenital Left Ventricular Outflow Obstruction Section D: Fallot’s Physiology Section E: Congenital Cyanotic Heart Disease with Continuous Murmur Section F: Congenital Cyanotic Heart Disease: Management Issues Section G: Unequal Pulse Section H: Constrictive Versus Restrictive Physiology Section I: Left to Right Shunt Section J: Right Ventricular Outflow Obstruction Section K: Electrocardiography Section L: X-Ray Chest Section M: Echocardiography Section N: Hemodynamic
£53.20
Jaypee Brothers Medical Publishers Manual of Heart Failure Management
Book SynopsisHeart failure is a serious condition caused by the heart failing to pump enough blood around the body at the right pressure. It usually occurs because the heart muscle has become too weak or stiff to work properly, most commonly caused by heart attack, high blood pressure or cardiomyopathy (heart disease). This book is a comprehensive guide to the diagnosis and management of heart failure. Divided into 81 sections, the book begins with an overview of heart failure, its epidemiology, types, assessment and diagnosis, and imaging. Each of the following chapters provides in depth detail on a different type or cause of heart failure, concluding with discussion on intravenous drug administration. With more than 100 contributors, the text is further enhanced by charts and tables, making it an excellent quick reference guide for both practising cardiologists and trainees. Key points Comprehensive guide to diagnosis and management of heart failure Covers numerous different types and causes More than 100 expert contributors Highly illustrated with charts and tables Table of Contents Epidemiology of Heart Failure in India Heart Failure: Definition and Types Diagnosis: Signs and Symptoms Systolic Function Assessment in Heart Failure by Echocardiography Echocardiographic Assessment of Diastolic Function in Heart Failure Workup for Heart Failure Cardiac Magnetic Resonance Imaging in Heart Failure Cardiac Catheterization in Heart Failure Natriuretic Peptides in Heart Failure Natriuretic Peptides in Heart Failure: Fallacies and Special Situations Other Biomarkers of Heart Failure: Troponin T, ST-2, and Atrial Natriuretic Peptide Ultrasound B Lines: Cardiologist’s Best Friend in Heart Failure Evaluation Guideline Directed Therapy for Heart Failure: Overview Angiotensin-converting Enzyme Inhibitors Therapy in Heart Failure Angiotensin Receptor Blockers: Role, Initiation, and Maintenance in Heart Failure Aldosterone Antagonists in Heart Failure Beta-blockers in Heart Failure Diuretic Therapy in Heart Failure: Initiation, Titration, and Maintenance Angiotensin Receptor–Neprilysin Inhibitors: Role, Initiation, and Maintenance in Heart Failure Ivabradine: Role in Heart Failure, Initiation, and Maintenance Digoxin Initiation and Maintenance Hydralazine and Nitrates: Initiation and Maintenance Drugs to be Avoided in Heart Failure Antidiabetic Drugs in Heart Failure Acute Decompensated Heart Failure—Inotropes: Catecholaminergic Agents Acute Decompensated Heart Failure—Inotropes: Noncatecholaminergic Agents Mechanical Circulatory Support for Heart Failure— Current Concepts Arrhythmia Management and Anticoagulation in Heart Failure Hyponatremia in Acute Decompensated Heart Failure Potassium Imbalances During Heart Failure Management Iron Deficiency in Heart Failure Surgical Management of Heart Failure Device Therapy in Heart Failure—Implantable Cardiac Defibrillators, Cardiac Resynchronization Therapy, and Cardiac Contractility Modulation Living with Heart Failure: Self-care Heart Transplantation Peripartum Cardiomyopathy—Diagnosis and Management Tachycardiomyopathy: Definition and Management Hypertrophic Cardiomyopathy—Diagnosis and Management Ischemic Cardiomyopathy Amyloidosis: Price of Longevity Restrictive Cardiomyopathy—Cardiac Sarcoidosis Alcoholic Cardiomyopathy Valvular Heart Disease and Heart Failure— Overview of Evaluation and Management Mitral Regurgitation and Heart Failure Aortic Stenosis and Heart Failure Aortic Regurgitation and Heart Failure Mitral Stenosis and Heart Failure Tricuspid Valve Disease and Heart Failure Myocarditis and Heart Failure: Evaluation and Management Chronic Constrictive Pericarditis Anticancer Therapy and Heart Failure: Management Heart Failure with Preserved Ejection Fraction: Burden in India, Diagnosis Heart Failure with Preserved Ejection Fraction: Nonpharmacological and Pharmacological Treatment Discharge Planning: How to Assess Residual Congestion? Reducing Readmissions in Heart Failure: An Evidence-based Update Exercise and Physical Activity Training in Heart Failure Diet and Fluid Restriction in Heart Failure When will You be Able to Stop Heart Failure Drugs? Medication Adherence in Heart Failure Depression in Heart Failure: Management Vaccination in Heart Failure Patients Prevention of Heart Failure Heart Failure Clinics in India: Step-by-Step Guide Renal Dysfunction and Heart Failure: Management Ultrafiltration and Dialysis in Acute Heart Failure Following Up of Patients with Heart Failure in the Outpatient Settings: Things to Remember The 6 Minute Walk Test Pulmonary Hypertension and Heart Failure Heart Failure with Recovered Ejection Fraction Etiology of Pediatric Heart Failure Pediatric Heart Failure—Clinical Features and Outcomes Evaluation and Diagnostic Workup of Pediatric Heart Failure Treating Pediatric Heart Failure: Pharmacotherapy and General Measures Shunt-related Heart Failure in Children Inflammatory Disorders of the Cardiovascular System Kawasaki Disease Fontan Failure: An Overview Postoperative Tetralogy of Fallot and Related Conditions Right Ventricle as Systemic Ventricle, Is It Right? Eisenmenger Syndrome Practical Tips for Intravenous Drug Administration
£48.45
Thieme Publishers Delhi Textbook of Cardiac Critical Care
Book SynopsisCardiac critical care is an emerging technology. The existing literature has bundles of protocols applied in cardiac critical care intensive care unit. However, there is no textbook that exists for students’ reference. For undergraduates, postgraduates, and paramedical staff in cardiac critical care medicine, the increased demand and growth in critical care for cardiac patients necessitates further training. Textbook of Cardiac Critical Care, a brand new, practical resource, helps meet that need. The cardiac critical care division worldwide is still in its infancy, but the book has taken up the challenges of developing this evolving specialty with the entire modern infrastructure at its disposal for state-of-the-art delivery of health care to the most critically ill adult and pediatric cardiac patients. Key Highlights: A straightforward approach, abundant detailed images, and latest references provide step-by-step guidance on the principles and effective use of important imaging modality in both diagnosis and assistance with specific procedures. Coverage includes the latest advances in ECMO, ECHO, and cardiac critical care. This must-have resource will help postgraduates in cardiac anaesthesia, surgery, cardiology, medicine, paediatrics, critical care, and ECMO specialists. This book includes complimentary access to a digital copy on https://medone.thieme.com. Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.Table of ContentsSection 1: Cardiac Critical Care 1. Surgical Anatomy of the Heart 2. Ventilator Modes in Cardiac ICU 3. Noninvasive Ventilation in the ICU 4. Ventilation-Associated Pneumonia 5. Decompensated Heart Failure 6. Hyponatremia in Heart Failure 7. Dyselectrolytemia in ICU 8. STEMI: Complications and Management 9. Central Nervous System Monitoring in Cardiac Surgery 10. The Role of NIRS in Postoperative Pediatric Cardiac ICU 11. Cardiac Implantable Electronic Devices and Anesthesia 12. Hemodynamic Monitoring in Cardiac Critical Care Units 13. Recent Advances in Cardiac Pharmacology: Infographics 14. Recent Advances in the Pharmacological Management of Pulmonary Hypertension 15. Surgical Treatment of Pulmonary Hypertension 16. Conduction Defects in ICU 17. Management of Cardiac Implantable Electronic Devices in Cardiac Surgery and Intensive Care 18. Antibiotics in Cardiac Surgery Section 2: Pediatric Cardiac Critical Care 19. Challenges in ALCAPA Repair 20. Future of Pediatric Cardiac Intensive Care 21. Acyanotic Congenital Heart Disease and Transesophageal Echocardiography 22. Pediatric Fluid Status Section 3: Lung Transplant Challenges 23. Preoperative Considerations in Lung Transplantation 24. Perioperative Concerns for Lung Transplantation 25. Postoperative Considerations in Lung Transplant 26. Extracorporeal Membrane Oxygenation as a Bridge to Transplant Section 4: COVID-19 in the ICU 27. Critical Care and Cardiac Services in the Current COVID Crisis (2020–2022) 28. Cardiac, Vascular, and Thrombotic Involvement in COVID-19 Infection 29. Hemostasis in COVID-19 Infection: Learnings So Far! 30. Antiviral Drugs 31. ECMO in COVID-19 Section 5: Extracorporeal Membrane Oxygenation (ECMO) In Cardiac ICU 32. Extracorporeal Membrane Oxygenation in Cardiac ICU 33. Patient Blood Management in ECMO Cardiac Critical Care 34. Simulation on Extracorporeal Membrane Oxygenation 35. ECMO and Sepsis 36. Indications and Contraindications of Extracorporeal Membrane Oxygenation 37. Monitoring of Extracorporeal Membrane Oxygenation 38. Perfusion Perspectives for Integrated Venoarterial ECMO: AIIMS Experience 39. Nutrition in Extracorporeal Membrane Oxygenation Patients 40. Extracorporeal Cytokine Hemoadsorption Therapy in the Management of ICU Sepsis 41. ECMO for Cardiodiabetes 42. Utility of ECMO in Accidental Poisoning and Intoxication 43. Intervention Lung Assist: Pumpless Extracorporeal and Paracorporeal Technology for Refractory Respiratory Failure 44. Utility of Extracorporeal Cardiopulmonary Resuscitation in Extracorporeal Cardiopulmonary Resuscitation 45. Importance of Mechanical-Assist Devices in Acute Decompensated Heart Failure Section 6: Essentials of Echocardiography In Cardiac ICU 46. Echocardiography in ECMO 47. Role of Transesophageal Echocardiography Examination for Aortic Pathology 48. Echocardiography for Left Ventricular Assist Device Management 49. Sonoanatomy for the Critical Care Physician 50. Ultrasound-Guided Vascular Access 51. POCUS-Based Protocols and Assessment of Fluid Responsiveness
£73.15
Springer Hypertensive Cardiovascular Disease: Pathophysiology and Treatment: Pathophysiology and Treatment
Book SynopsisHypertension is a major world-wide health problem. With high blood pressure there is a greater risk of stroke, heart attack, heart failure, kidney disease and renal failure. Far too few people realize what the risks are and what can be done to prevent these risks even in the countries where pro grams in hypertension research are active and the full significance of hyper tension is best understood. Some studies of the known hypertensive popu lation indicate that one-half or less are receiving adequate treatment, and, of those on therapy, only half have their high blood pressure satisfactorily controlled. These realizations emphasize the need to inform all segments of society throughout the world on the importance of detection and control of high blood pressure. The great incidence of hypertension makes it of para mount importance that all practicing physicians have available the latest information on diagnosis and treatment of hypertensive cardiovascular dis ease. This treatise on hypertension arrives at a time when there is an increasing recognition the world over of the importance of detecting and treating high blood pressure. The book has been edited by Dr. A. Amery and his asso ciates in the University of Leuven. Professor Amery is one of the leaders in the field of hypertension and serves on the Council of the International Society of Hypertension.Table of ContentsI. Blood Pressure Control in Normotensive Subjects.- 1. Role of the kidney in blood pressure regulation.- 2. Role of central mechanisms in the blood pressure regulation.- 3. Arterial baroreflexes in normotensive and hypertensive man.- 4. Role of catecholamines in blood pressure regulation.- 5. Role of the renin-angiotensin system and prostaglandins in blood pressure regulation and sodium homeostasis.- 6. Role of kallikrein in blood pressure regulation.- 7. The lability of blood pressure.- II. Experimental Hypertension.- 8. Pathophysiology of hypertension in genetically hypertensive rats — environmental modification and prevention.- 9. The pathophysiology of hypertension: contributions of experimental pathophysiology.- III. Pathogenesis of Primary Hypertension.- 10. Role of changes in Na+ transport in cell membranes in the pathogenesis of primary hypertension.- 11. Pathophysiology of primary hypertension: role of adrenoceptors in the transformation from an early high cardiac output into a later high arteriolar resistance phase.- 12. Genetics in human hypertension.- 13. Psychophysiologic evidence for the role of the nervous system in hypertension.- 14. Interaction between functional and structural elements in primary hypertension.- 15. Role of the kidney in the pathogenesis of primary hypertension.- 16. Role of sodium in the pathogenesis of idiopathic hypertension.- 17. Role of obesity in the pathogenesis of primary hypertension.- 18. Role of catecholamines in the pathogenesis of primary hypertension.- 19. Role of renin in the control of the circulation in hypertensive disease and in heart failure.- 20. Blood pressure in the first years of life.- 21. Childhood hypertension.- 22. Hypertension in elderly.- 23. Borderline blood pressure elevation.- 24. Hemodynamics of primary hypertension.- IV. Repercussions of High Blood Pressure.- 25. Hypertension and the brain.- 26. The ocular fundus and hypertension.- 27. Influence of hypertension on the heart.- 28. Influence of hypertension on the kidney.- 29. Influence of hypertension on mortality.- 30. Malignant hypertension.- 31. Definition and classification of hypertension.- V. Secondary Hypertension.- 32. Hypertension secondary to coarctation.- 33. Hypertension secondary to renal parenchymal disease.- 34. Hypertension secondary to renovascular disease.- 35. Hypertension secondary to adrenal cortical disease.- 36. Hypertension secondary to pheochromocytoma.- 37. Hypertension secondary to thyroid dysfunction.- 38. Parathyroid function and hypertension.- 39. Hypertension in pregnancy.- 40. Hypertension secondary to contraceptive agents.- VI. Examination of the Hypertensive Patient.- 41. Clinical examination of the hypertensive patient including blood pressure measurement.- 42. Laboratory examination of the hypertensive patient.- 43. Radiological examination of the hypertensive patient.- VII. Antihypertensive Therapy.- 44. Non-drug treatment of hypertension.- 45. Diuretics as antihypertensive agents.- 46. Beta-adrenoceptor blocking drugs as antihypertensive agents.- 47. Alpha-adrenoreceptor antagonists in hypertension.- 48. Vasodilators as antihypertensive agents.- 49. Methyldopa as an antihypertensive agent.- 50. Clonidine and imidazolines as antihypertensive agents.- 51. Blockers of the neuromuscular junction as antihypertensive agents.- 52. Ganglion blockers as antihypertensive agents.- 53. Inhibitors of the renin-angiotensin system as antihypertensive agents.- 54. General strategy of antihypertensive treatment.- 55. The benefits of antihypertensive therapy.- 56. Hypertensive emergencies.- 57. Anesthesia and surgery in the hypertensive patient.- 58. Quality of life in hypertensive patients.- 59. Compliance to antihypertensive therapy.- Index of Authors.- Drug Index.
£40.49
Springer Cardiac Dynamics
Book SynopsisCardiac Dynamics is the name of a relatively young field of study, born from the fruitful interaction between branches of two different disciplines: medicine and physics. "Dynamics" is the branch of physics which deals with the action of forces on bodies or particles in motion or at rest. "Cardiac" relates to the clinical field of cardiology but also to cardiophysiology, both of which are specialized branches of medicine. Narrower than the well established field of Hemodynamics, Cardiac Dynamics is restricted to dynamic phenomena occurring in and around the heart. The mathematical treatment of such phenomena, however, is vastly more complex because of the intricate nature of the mechanisms involved in the cardiac action. Thus, whereas hemodynamics is concerned with predominantly passive (visco-) elastic structures - vessels - containing time-variant flow of viscous flui- blood -, the mechanical study of the heart requires additional con siderations such as: active elastic components representing the contractile mechanism of cardiac muscle, complex geometry and fiber structure in the myocardial wall, autoregulatory mechanisms, and intricate flow patterns associated with valve motion. Viewed in this light it is not surprising that attempts to describe ventricular pump function and to quantify contractile performance have not reached the level of sophistication which is common in e. g. arterial hemodynamics. For the same reason, many of the often simplified approaches to describe ventricular mechanics failed to stand up to more rigorous theoretical, experimental or clinical testing.Table of ContentsSection 1: Cardiac Muscle Mechanics: From the Fiber Down to the Sarcomere.- 1.1 The coming of age of cardiac muscle mechanics.- 1.2 The importance of passive elements in the contraction of the heart.- 1.3 Tension development and sarcomere length in rat cardiac trabe-culae: evidence of length-dependent activation.- 1.4 Inseparability between preload and contractility effects on pressure development in the isovolumically contracting isolated rabbit heart.- 1.5 Force-velocity-length relations in cardiac muscle segments.- 1.6 Theoretical and experimental force-velocity relations of the ventricular myocardium.- 1.7 Time course of changes in action potential duration and ejection shortening during regional transient ischaemia of pig ventricle in situ.- 1.8 A quantitative analysis of the force transients of skeletal muscle in response to quick changes in length.- Section 2: Cardiac Chamber Dynamics: From the Fiber up to the Myocardium.- 2.1 A fundamental similarity between isolated muscle mechanics and cardiac chamber dynamics.- 2.2 The chamber dynamics of the intact left ventricle.- 2.3 LV wall fibre pathways for impulse propagation.- 2.4 Transmural course of stress and sarcomere length in the left ventricle under normal hemodynamic circumstances.- 2.5 The role of wall thickness in the relation between sarcomere dynamics and ventricular dynamics.- 2.6 A model for left ventricular contractions based on the sliding filament theory.- Section 3: Pump Function and Filling: Interaction with the Low Pressure System.- 3.1 Dynamic determinants of left ventricular filling: an overview.- 3.2 Effects of the pericardium on left ventricular performance.- 3.3 Blood flow dynamics during the human left ventricular filling phase.- 3.4 Relaxation of the left ventricle.- 3.5 Intramural stress and strain analysis in the intact heart.- 3.6 Effects of intravenous isosorbide dinitrate on filling pressures and pump function in patients with refractory pump failure.- 3.7 Transfer function model of the heart.- 3.8 Dynamics of sequential large pulmonary emboli.- Section 4: Pump Function and Ejection: Interaction with Systemic Load and Coronary Perfusion.- 4.1 Pump function and its interaction with the systemic load.- 4.2 Quantification of extravascular coronary resistance.- 4.3 Studies on the optimal matching between heart and arterial system.- 4.4 End-systolic pressure as direct determinant of stroke volume from fixed end-diastolic volume in isolated canine left ventricle.- 4.5 Pump function of the left ventricle evaluated from pressure-volume loops.- 4.6 Simulation study of flow distribution across myocardium.- 4.7 Experimental studies: the appearance of large coronary arteries during arteriography.- 4.8 Hemodynamic effects of reductions in coronary blood flow caused by mechanical stenosis and platelet aggregates forming in dog coronary arteries.- Section 5: Measuring Cardiac Performance: Aims and Validity of Invasive and Noninvasive Measurement.- 5.1 Isaac Starr Lecture: Invasive and noninvasive monitoring of cardiovascular dynamics in clinical practice.- 5.2 Measuring cardiac performance: aims and validity of invasive and noninvasive assessment.- 5.3 The clinical usefulness of noninvasive and invasive tools in the assessment of left ventricular function in myocardial infarction.- 5.4 Model-based hemodynamic indicators of left ventricular performance.- 5.5 Comparative evaluation of myocardial performance factors.- 5.6 Circulatory changes during isometric exercise measured by transcutaneous aortovelography.- 5.7 Validity of parameters of ventricular performance determined by radiocardiography in patients with coronary artery disease.- 5.8 Assessment of the dynamics of cardiac responses to positive inotropic agents.- 5.9 Assessment of cardiac function in the dog by cross-sectional echocardiography.- 5.10 Dynamics of the left ventricular centre of mass in intact unanaesthetized man in the presence and absence of wall motion abnormalities.- 5.11 Cardiac pump function by ballistocardiogram: normal standards and comparison with coronary arteriograms.- Section 6: Energy Losses: Hemodynamics of Valves.- 6.1 Konrad Witzig Memorial Lecture: Some fluid mechanic theories and their application to the design of heart valves and membrane lungs.- 6.2 Fluid dynamics in the aorta.- 6.3 The closing behaviour of the natural aortic valve.- 6.4 Fluid mechanics of the aortic valve.- 6.5 Mechanical energy losses resulting from stenosis of semilunar valves.- 6.6 Pressure-flow relations and energy losses across prosthetic mitral valves: in vivo and in vitro studies.- 6.7 Blood flow velocity in subclavian artery and through mitral valve measured with transcutaneous Doppler ultrasound. The effects of exercise and mitral valve disease.- Closing Lecture: Approaching the heart of the matter.
£40.49
Springer Echocardiology: with Doppler applications and Real time imaging
Book SynopsisEchocardiology comprises all aspects of diagnostic application of ultrasound to cardiac patients. It is probably the fastest growing non-invasive technique today. Almost all progress in this young and exciting field has been the positive result of close co-operation between medical and technical scientists. This book contains a series of lectures held at Erasmus University Rotterdam in June 1977 and is divided in three sections: - clinical echocardiology, consisting of both an introduction to the basic principles as well as a wide variety of applications aimed at the clinically oriented reader. - Doppler methods, where in addition to its clinical applications also the engineering of new developments will be presented. - the two dimensional real-time imaging where many new techniques including com puter methods, holography and acousto-optical systems will be discussed. We hope that this book will stimulate communication between scientists of various disciplines and nationalities. N.Bom J. Roelandt P.G. Hugenholtz Rotterdam, June 1977 III Preface The last three decades have seen a remarkable advance in diagnostic instrument ation in diseases of the circulation. In the 1940's the only diagnostic aids were the electrocardiogram and simple X-ray. These were quickly followed by the cardiac ca theter, phonocardiography, radio isotope methods and angiocardiography. The de velopment of cardiac surgery provided the impetus to developing more accurate methods of diagnosis, preferably those that did not need invasion of the patient. The introduction of ultrasound has contributed towards this aim in the last few years.Table of ContentsClinical Echocardiology.- The future of echocardiography as scanned by an outsider.- Principles of ultrasound in medical diagnosis.- Echocardiographic examination techniques.- Echocardiographic examination of the aortic root and aortic valve.- Right-sided heart valves.- Cross-sectional echocardiographic evaluation of the Atrioventricular valves in acquired and congenital heart disease.- Screening, population and sequential follow-up.- Echocardiologic Assessment in Asymmetric Septal Hypertrophy (ASH).- Mitral valve prolapse.- A dual M-mode system for simultaneous time motion analysis of cardiac structures and evaluation of cardiac function: initial clinical applications.- Advantages of combined hemodynamic and ultrasonic studies in man.- Detection of incoordinate left ventricular contraction by echocardiography.- Cardiac anatomy in congenital heart disease.- Echocardiography in noncyanotic congenital heart disease.- Real-time Assessment of Fetal Dynamics.- Echocardiography in a general cardiologic practice.- Contrast echocardiology.- Echocardiographic assessment of cardiomyopathies.- Left ventricular wall motion in patients with W.P.W. syndrome studied by echocardiography.- Doppler instruments and applications.- Continuous wave and pulsed Doppler flowmeters — general introduction.- Pulsed Doppler echocardiography.- Applications of pulsed Doppler systems.- Aortic blood velocity measurement by transcutaneous aortovelography and its clinical applications.- Echo-Doppler systems; Applications for the detection of cardiovascular disorders.- A transcutaneous N-channel digital Doppler.- Two-dimensional real time imaging.- Real time systems for two-dimensional imaging — general introduction.- 2D imaging versus holography and 3D imaging.- Acoustical image reconstruction devices.- Mechanical sector scanners.- A dynamically focused multiscan system.- Phased array systems.- Data processing of time-motion information in Echocardiography.- Author index.
£40.49
Springer Cardiac Positron Emission Tomography: Viability, Perfusion, Receptors and Cardiomyopathy
Book SynopsisMyocardial viability has become one of the most important issues in clinical cardiology. In particular, absence or presence of viability may be decisive in patient management, and the decision to perform angioplasty (PTCA) or bypass surgery (CABG) is frequently based on the accurate assessment of viability. Although echocardiography and conventional nuclear medicine techniques may provide valuable information on viability, positron emission tomography (PET) is currently considered to be the gold standard for the assessment of myocardial viability. The simultaneous evaluation of myocardial metabolism and perfusion allows precise delineation and accurate quantification of residual myocardial viability in affected regions. In addition, accurate quantification of myocardial perfusion alone may provide insight into the basic mechanisms of syndrome X and may assist in the appropriate clarification of this clinically complicated, but frequently occurring phenomenon. Besides that, cardiac PET may deepen our insight into metabolism and perfusion of cardiac muscle disease, particularly in hypertrophic cardiomyopathy. Furthermore, receptor imaging studies with PET will become important as the study of cardiac neurohumoral regulation in heart failure has gained in interest. Cardiac Positron Emission Tomography: Viability, Perfusion, Receptors and Cardiomyopathy describes the most recent developments in cardiac PET as these are related to myocardial viability and myocardial perfusion studies of syndrome X. The value of PET for receptor imaging and cardiac muscle disease is also discussed. For cardiologists, nuclear medicine physicians, radiochemists, physiologists, technicians and basic researchers interested in understanding the most recent achievements in cardiovascular PET. Trade Review`This small, condensed and well-produced book gives a detailed account of the cardiac PET conference ... The book is clearly inteded for committed investigators and clinicians whose main interest is cardiology, but it is highly recommended as an up-to-date well-produced publication that deserves to be read, digested and kept for future specialized reference.' European Journal of Nuclear Medicine 22:10, 1995Table of ContentsPreface; W. Vaalburg, Kong I. Lie. Foreword; E.E. van der Wall, P.K. Blanksma, M.G. Niemeyer, A.M.J. Paans. State of the art in cardiac positron emission tomography; P.G. Camici. Part One: Myocardial Viability. 1. Myocardial viability: stunning and hibernation; W. Flameng, B. Shivalkar, M. Borgers. 2. Positron emission tomography assessment of myocardial viability; Eng-Shiong Tan. 3. Comparison of thallium scintigraphy and positron emission tomography; M.G. Niemeyer, J.G. Meeder, A.F.M. Kuijper, P.K. Blanksma, E.E. van der Wall. 4. Cardiac metabolism: positron emission tomography versus single photon emission computed tomography; E.E. van der Wall. 5. The role of fluorine-19-deoxyglucose single photon emission computed tomography in predicting reversibility of regional wall motion abnormalities after revascularization; J.J. Bax, J.H. Cornel, F.C. Visser, P.M. Fioretti, A. van Lingen, J.M. Huitink, O. Kamp, G.J.J. Teule, C.A. Visser. 6. Parametric positron emission tomography imaging of myocardial perfusion and metabolism; A.T.M. Willemsen, P.K. Blanksma, A.M.J. Paans. 7. Positron emission tomography compared to single photo emission computed tomography in the evaluation of myocardial viability: a preliminary cost-effectiveness analysis; M.G.M. Hunink. 8. Assessment of myocardial viability by pharmacological stress echocardiography; J.H. Cornel, M.P. Fioretti. 9. Assessment of myocardial viability by magnetic resonance imaging techniques; C.A. Schneider, F. Baer, E. Voth, P. Theissen, U. Sechtem. Part Two: Hypertrophic Cardiomyopathy. 10. Classification of hypertrophic cardiomyopathy with magnetic resonance imaging compared with echocardiography; J.L. Posma, P.K. Blanksma, Kong I. Lie. 11. Positron emission tomography characterization of the myocardium in hypertrophic cardiomyopathy; P.K. Blanksma, J.L. Posma, R.M. de Jong, J. Pruim, A.T.M. Willemsen, R.L. Anthonio, E. van der Wall, W. Vaalburg, Kong I. Lie. 12. Treatment of hypertrophic obstructive cardiomyopathy with pacing; L. Kappenberger, X. Jeanrenaud, N. Aebischer. Part Three: Receptor Imaging Studies. 13. Heart failure and the cardiac beta-adrenoceptor; O.-E. Brodde. 14. Study of cardiac receptor ligands by positron emission tomography; A. van Waarde, P.H. Elsinga, R.L. Anthonio, T.J. Visser, P.K. Blanksma, G.M. Visser, A.M.J. Paans, W. Vaalburg. 15. Assessment of sympathetic cardiac innervation by scintigraphic techniques; G. Münch, Ngoc Nguyen, D. Wieland, M. Schwaiger. 16. Experimental and clinical cardiac beta-receptor studies; R.L. Anthonio, A. van Waarde, A.T.M. Willemsen, J. Pruim, W.H. van Gilst, P.K. Blanksma, W. Vaalburg, Kong I. Lie. Part Four: Myocardial Perfusion. 17. Methodological issues in regional myocardial perfusion imaging with positron emission tomography; A. Bol, W. Wijns, J.A. Melin. 18. Altered autonomic control of the cardiovascular system in syndrome X; J.G. Meeder. 19. Positron emission tomography studies of cardiac neurostimulation; R.W.M. Hautvast. Index.
£42.74
Springer Nuclear Cardiology in Everyday Practice
Book SynopsisThe most salient feature of the infor last four chapters of the book evaluate the mation provided by nuclear medicine is its information from an analytical and pathophysiological and functional charac statistical point of view. This approach is ter. For adequate experimental or clinical required for correct decision-making. interpretation, such information should This book is therefore the result of necessarily be interpreted alongside the accumulated experience in nuclear cardiology views of the clinical cardiologist, who is with the invaluable cooperation of medical able to apply it to the individual patient. statisticians. It is directed to physicians This approach, which is routine in every with an interest in nuclear cardiology, to day clinical practice, reaches its plenitude nuclear medicine specialists wishing to when the whole process is completed and learn the uses and limitations of these an intimate cooperation is established procedures in everyday clinical cardiology, between the nuclear medicine specialist and to cardiologists who feel the need to and the clinical cardiologist. In such understand the rationale and methodology instances, each one of these professionals of the studies which benefit their patients. understands the needs, limits and possi We understand that the ultimate reason bilities of the other. for any scientific book is the transmission The present book is the fruit of such of knowledge, and we are fully conscious cooperation. In our hospital, an efficient of the enthusiasm of the authors of the nuclear cardiology team has been made up present text to achieve that aim.Trade Review... about the Spanish edition ... ` I can unreservedly recommend this book to doctors, radiologists and cardiologists working in nuclear medicine and imaging with radionuclides. It is a most useful source of reference ... it will be extremely well received. ' P.J. Ell in European Jrnl of Nuclear Medicine, 19 Table of ContentsForeword; F.M. Domènech-Torné, J. Soler-Soler. Preface; P. Ell. Introduction; J. Candell-Riera, D. Ortega-Alcalde. 1. Physicochemical and technical fundamentals; P. Galofré-Mora. 2. Image processing; D. Ortega-Alcalde. 3. Stress testing; J. Candell-Riera. 4. Myocardial perfusion studies; D. Ortega-Alcalde. 5. Methods for quantifying myocardial perfusion; J. Castell-Conesa. 6. Studies of myocardial damage and viability; M. Fraile. 7. First-pass radionuclide ventriculography; S. Aguadé-Bruix. 8. Gated blood-pool radionuclide ventriculography; D. Ortega-Alcalde. 9. Ventricular volume measurement; J. Castell-Conesa. 10. Parametric images and Fourier's analysis; D. Ortega-Alcalde. 11. Diagnosis of coronary artery disease; J. Candell-Riera. 12. Prognostic evaluation and follow-up of chronic coronary artery disease; J. Candell-Riera. 13. Diagnosis of acute myocardial infarction; J. Cortadellas-Angel. 14. Prognostic evaluation after acute myocardial infarction; A. Rius-Daví. 15. Congenital heart disease; E. Galve. 16. Valvular heart disease; M.P. Tornos-Mas. 17. Cardiomyopathies; J. Candell-Riera. 18. Methods for diagnostic evaluation; J. Rosselló-Urgell. 19. The probability of a correct diagnosis; M. Olona-Cabases. 20. Uses of multiple logistic regression; J. Vagué-Rafart. 21. Cost analysis and decision trees; B.Bermejo-Fraile. Index.
£161.99
Springer Practical Management of Hypertension
Book SynopsisWILLEM H. BIRKENHA. GER This compact guide aims to define the current approach to hypertension in practice, with the focus on the individual whom the physician faces across his desk. In the population, blood pressures are distributed along a Gaussian type of curve, but with some tailing towards the upper range. A systolic blood pressure of 160 mmHg is commonly accepted as the upper limit of the normal range. For diastolic pressure, the gradings are much more detailed: borderline hypertension (90-94 mmHg, mild hypertension (95-104 mmHg), moderate hypertension (105-114 mmHg), and severe hypertension (115 mmHg and over). Despite its skewing to the right, the bell shape of the distribution curve of blood pressures implies that the milder elevations of blood pressure are the most common. Such pressures are observed in 15-20% of the population upon casual measurement. After rechecking - which is mandator- the prevalence of hypertension drops to some 5%, due to psychological and statistical factors. Even this modest segment of the population represents an important proportion in terms of future cardiovascular risk. It is an essential part of preventive and curative health care to identify these people; the more so, because some 40% of the excess risk has already been proven to be reversible by conventional antihypertensive treatment.Table of Contents1. Techniques for measuring blood pressure and their interpretation.- 2. Pathophysiological basis of hypertension.- 3. Cardiovascular risk associated with hypertension; interactions with other risk indicators.- 4. Evaluation of the hypertensive subject.- 5. Special situations in hypertension (childhood and adolescence; pregnancy; old age).- 6. How to deal with secondary hypertension.- 7. Non-pharmacological intervention Roger.- 8. Drug treatment: efficacy and adverse effects. Specific responses in patients sub-groups and treatment approach.- 9. Predictability, assessment and improvement of compliance with regard to taking antihypertensive drugs.
£40.49
Springer Clinical Echocardiography
Book SynopsisRecently, much progress has been made with echocardiography and Doppler techniques and these ultrasound methods have grown in importance and reliability as non-invasive diagnostic procedures for many cardiovascular disorders. The objective of this t~xtbook is to offer a detailed yet concise overview of the echocardiographic diagnosis of the various cardiovascular diseases. The book focuses upon the practical echocardiographic (including Doppler) exam ination. Accordingly, the fundamental principles of echocardiography and the Doppler techniques (pulsed and continuous wave and color flow mapping are covered briefly but comprehensively). A copious amount of representative figures and illustrations is included so that the reader is able to understand the clinical application of each modality in the various cardiovascular pathologies and the echocardiographic diagnosis. In keeping with the concept of an integrated echocardiographic examination, the two-dimensional, M-mode and Doppler echocardiographic findings are included in many of the diseases. Usually, the echocardiographic examination is approached first by two-dimensional imag ing to give an understanding of the anatomical correlations, if necessary adding M-mode to clarify the time course of intracardiac movements, and secondly by each Doppler technique to evaluate the hemodynamic conditions. When familiar with these approaches, one can make not only the diagnosis of many cardiovascular diseases with echocardiography alone, but also the rational and expeditious management of patients. Today, some of the cardiac diseases (Atrial Myxoma, Atrial Septal Defect, Infective endocarditis and so forth) have been oper ated based only on echocardiographic findings.Table of Contents1. The basics of cardiac ultrasound.- Physical properties of ultrasound.- Cardiac ultrasound imaging systems.- Doppler echocardiography.- 2. Echocardiographic examination.- Placement of the transducer.- Two-dimensional examination of the heart.- A. Left ventricular long axis view.- B. Left ventricular short axis view.- C. Four chamber view.- M-mode examination.- Contrast echocardiography.- Pulsed Doppler examination.- A. Left ventricular outflow.- B. Left ventricular inflow.- C. Right ventricular outflow.- D. Right ventricular inflow.- Continuous wave (CW) Doppler examination.- High PRF Doppler examination.- 3. Acquired valvular heart disease.- Mitral valve stenosis.- Giant left atrium.- Mitral valve regurgitation (rheumatic in origin).- Mitral valve prolapse.- Ruptured chordae tendineae.- Aortic valve stenosis.- Aortic valve regurgitation.- Infective endocarditis.- Tricuspid valve stenosis.- Tricuspid valve regurgitation.- Pulmonary valve regurgitation.- Prosthetic valve.- 4. Congenital heart disease.- Atrial septal defect.- Endocardial cushion defect.- Persistent left superior vena cava.- Ventricular septal defect.- Sinus of Valsalva aneurysm.- Patent ductus arteriosus.- Pulmonary stenosis.- Ebstein’s anomaly.- Tetralogy of Fallot.- Double outlet of the right ventricle.- Single ventricle.- Corrected transposition of great arteries.- Tricuspid atresia.- Cor triatriatum.- Bicuspid aortic valve.- Supravalvular aortic stenosis.- Coronary artery fistula.- Anomalous origin of the left main coronary artery from the pulmonary trunk.- Marfan’s syndrome.- 5. Coronary artery disease.- Wall motion abnormalities.- Wall thickening and echo intensity abnormalities.- Complications of myocardial infarction.- A. Ventricular aneurysm.- B. Mural thrombus of the left ventricle.- C. Rupture of the ventricular septum.- D. Mitral regurgitation.- E. Right ventricular myocardial infarction.- Ischemic cardiomyopathy.- Examination of coronary arteries.- 6. Myocardial diseases.- Hypertrophic cardiomyopathy.- Dilated cardiomyopathy.- Secondary cardiomyopathy.- Inflammatory process of the myocardium.- Myocardial abnormality due to toxic agents.- 7. Other cardiac diseases.- Left atrial myxoma.- Right atrial myxoma.- Intracardiac rhabdomyoma.- Left ventricular fibroma.- Malignant primary cardiac tumor.- Secondary tumors of the heart.- Pericardial effusion.- Pleural effusion.- Constrictive pericarditis.- Pericardial defect.- False tendon.- Chiari network.- Atrial septal aneurysm.- Sigmoid septum.- Mitral anular calcification.- Aneurysm of the aorta.- Primary pulmonary hypertension.- 8. Evaluation of left ventricular function.- M-mode echocardiography.- Two-dimensional echocardiography.- Doppler method.- A. Evaluation of systolic function.- B. Evaluation of diastolic behavior.- 4. Age related changes in the left ventricular function.- 9. Pulmonary hypertension.- M-mode echocardiographic evaluation.- Pulsed Doppler evaluation.- 10. Echocardiographic evaluation of arrhythmia.- Bundle branch block.- Wall-Parkinson-White (WPW) syndrome.- Atrial fibrillation.- Atrial flutter.- Ectopic atrial rhythm.- Supraventricular premature contraction.- Ventricular premature contraction.- Abnormal atrio-ventricular conduction.- Cardiac pacing.- 11.Color coded Doppler flow mapping.- References.- Additional references.- Index of subjects.
£42.74
Springer Commonsense Cardiology
Book SynopsisCardiology embraces a number of different conditions and disease processes. Cardiovascular disease is now responsible for most of the deaths of adults, especially premature deaths, in the developed world. The development of effective preventive measures, new drugs and surgical techniques makes it increasingly important to recognise those at risk, to diagnose accurately those suffering from disease and to prescribe, monitor and refer appropriately. This book is intended to focus attention on the opportunities which family' practice provides for this and to look at the need for a change in emphasis in approaching the problems. The book is in five parts. Part 1 is a reminder of some of the basic principles, which are essential if sensible cardiology is to be practised. Part 2 is about cardiac drugs, their use, effectiveness and risks. Part 3 looks at the diagnostic process; it comprises the history, examination, investigation and referral of patients, who might have cardiac disease and also the drugs which are most likely to be used. Part 4 is devoted to specific conditions. In Part 5, we look at the need for prevention and consider how it may be tackled in general practice. This is not a comprehensive textbook of cardiology. It is not intended for students. It is hoped that it may be useful to experienced doctors, struggling to provide a sound, sensible service in an environment of ever expanding technology.Trade Review`This splendid book is written by two general practitioners hoping to bring the mysteries of cardiology to the fingertips of all those engaged in family practice ..., and does indeed bring commonsense to cardiology. It can be recommended to all those wishing for an introduction to the subject.' Robert H. Anderson, International Journal of Cardiology, No. 28, 1990, pp. 129-131Table of Contents1: The Basics.- 1.1 Introduction.- 1.2 Basic Anatomy.- 1.3 Physiological models.- 1.4 Electrophysiology.- 2: Cardiac Drugs.- 2.1 Introduction.- 2.2 Hazards, safety and effectiveness.- 2.3 Sorting out the drugs.- 3: The Diagnostic Process.- 3.1 Introduction.- 3.2 Clinical history.- 3.3 Sorting out the symptoms.- 3.4 Examination.- 3.5 Electrocardiology.- 3.6 Pathology tests and chest X-rays.- 4: Cardiac Disease.- 4.1 Introduction.- 4.2 Ischaemic heart disease.- 4.3 Heart failure.- 4.4 Essential hypertension.- 4.5 Arrhythmias.- 4.6 Valvular disease.- 4.7 Congenital heart disease.- 4.8 Bacterial endocarditis.- 4.9 Cardiomyopathies.- 4.10 Pulmonary embolism.- 4.11 Pregnancy.- 4.12 Care of the patient dying of heart disease.- 5: The Role of General Practice.- 5.1 Introduction.- 5.2 Risk factors and prevention.- 5.3 The role of the Primary Health Care Team.- Further reading.
£40.49
Springer Eicosanoids in the Cardiovascular and Renal Systems
Book SynopsisThe original series, Advances in Prostaglandin Research, edited by Sultan M. M. Karim, was published by MTP Press in three volumes in 1975 and 1976. A glance at those books illustrates the progress that has been made since then. The thromboxanes were mentioned twice (first publication 1975) and prostacyclin not once (first publication 1976); leukotrienes were only on the horizon. The amazing generation of research data in the last 10-15 years has given new, broad insights into many areas, including asthma, inflammation, renaL cardiovascular and gastrointestinal diseases and in reproduction, and has led in some instances to real clinical benefit. This series, Advances in Eicosanoid Research, reflects the current understanding of prostaglandins, thromboxanes and leukotrienes. The aim is to provide an introductory background to each topic and the most up-to-date information available. Although each book stands alone, the eicosanoids cut across many boundaries in their basic actions; selected chapters from each book in the series will provide illuminating and productive information for all readers which will advance their education and research. In the production of this series, I must acknowledge with pleasure my collaboration with editors and authors and the patient endeavours of Dr Michael Brewis and the staff at MTP Press.Trade Review`... adds considerably to the attractiveness of this volume. This volume can be recommended as a good reference book for medical students and graduates of medical school.' Eicosanoids, 2/63-64, 1989 Table of Contents1 Arachidonic acid metabolism and platelet function.- 2 Renal arachidonic acid metabolism.- 3 Arachidonic acid metabolism in renal disease.- 4 Eicosanoids and pulmonary injury.- 5 Eicosanoids in sepsis and its sequelae.- 6 Eicosanoids in myocardial ischaemia and injury.- 7 Prostanoids in clinical and experimental hypertension.- 8 Prostacyclin receptors.- 9 Platelet and vascular smooth muscle thromboxane A2/prostaglandin H2 receptors.- 10 Mechanisms of action of prostaglandin E2 and prostaglandin F2?: PGE and PGF? receptors.
£40.49
Springer Basic Concepts in Doppler Echocardiography: Methods of clinical applications based on a multi-modality Doppler approach
Book SynopsisBasic Concepts in Doppler Echocardiography The objective of this textbook is to offer a detailed yet concise overview of the various applications of Doppler echocardiography. The fundamental principles of pulsed mode, continuous mode, and color flow mapping are fully explained as well as the clinical applications of each modality in the evaluation of various cardiac pathologies. A copious amount of figures and illustrations is included so that the reader is able to follow the discussions in the text by referring to the appropriate case studies. The emphasis of this book is focused upon the practical Doppler examination. The sections on theoretical considerations are therefore brief but comprehensive, while the didactic sections concentrate upon how to perform and interpret the clinical examination. The instrumentation of the Doppler system is also discussed so that the physician or technologist can acquire a basic understanding of how the Doppler system actually functions. CONTRmUTORS Bjorn AJ. Angelsen Dr. Tech. Professor of Biomedical Engineering University of Trondheim Trondheim , Norway Phillip Brun M. D. Director of Research Department of illtrasonology University Medical Center, Henri Mondor Paris , France Albert Meguira M. Sc. Biomedical Engineer Sonotron / Diasonics Paris , France and the Department of illtrasonology University Medical Center, Henri Mondor Paris , France Andreas Strauss M. D. Department of illtrasonology University Medical Center, Henri Mondor Paris France Sandra Yanushka B. Sc.Table of Contents1 Basic Principles.- Sound Wave Propagation.- The Ultrasound Beam.- The Doppler Effect.- Pulsed Doppler.- High Pulse Repetition Mode.- Continuous Wave Doppler.- Color Flow Mapping.- 2 On The Design of A Color Flow Imaging System.- Technical Problems with Color Flow Imaging.- Scan methods.- Phased Annular Array.- 3 Intracardiac Flow Dynamics.- Entrance Flow.- Pulsatile Flow.- Turbulant Flow.- Cardiac Output Measurement.- 4 The Normal Examination.- The Imaging Windows.- Characteristics of Normal Intracardiac Flows.- 5 Applications In Acquired Heart Disease.- Determination of the Pressure Gradient.- Aortic Stenosis.- Mitral Stenosis.- Tricuspid Stenosis.- Pulmonary Stenosis.- Aortic Insufficiency.- Mitral Insufficiency.- Pulmonary Insufficiency.- Tricuspid Regurgitation.- Prosthetic Valves.- Obstructive Cardiomyopathy.- Dilated Cardiomyopathy.- 6 Doppler Ultrasound in Congenital Heart Disease.- The Pulmonary to Systemic Flow Ratio.- Ventricular Septal Defect.- Atrial Septal Defect.- Patent Ductus Arteriosus.- Estimation of Systolic Pulmonary Artery Pressure.- Obstructive Lesions.
£40.49
Springer Ultrasonic Diagnosis of Cerebrovascular Disease: Doppler Techniques and Pulse Echo Imaging
Book SynopsisThis book is designed as a definitive report on current capabilities of ultrasound imaging and Doppler evaluation of the cerebral circulation, both extracranial and intracranial. The basic chapters are directed to the beginner in ultrasound and hemodynamics and for the expert in updating newly available modalities and techniques new to the field. The ultrasonic and hemodynamic principles are presented for physicians and vascular technologists in a practical way to avoid unnecessary mathematics. The aim is for maximum clinical utilization so that available equipment may be used more efficiently and provide more accurate diagnosis. The selection of authors represents a wide range of the expertise available in the world today. M.P. Spencer Contents Preface V Contributors IX 1. Introduction 1 Merrill P. Spencer, M.D. 2. Ultrasound physical concepts 7 Merrill P. Spencer, M.D., Ronald E. Hileman, Ph.D., John M. Reid, Ph.D 3. Doppler instrumentation 29 Robert S. Reneman, MD., Ph.D., A.P.G. Hoeks, Ph.D. 4. Normal anatomy, anatomical anomalies and collateral Pathways of the blood supply to the brain 43 Robert Ackerstaff, M.D. 5. Normal blood flow in the arteries 57 Merrill P. Spencer, M.D. 6. Normal physiology and pathophysiology of human cerebral blood fuw ~ P.C.M. Mosmans, M.D., E.J. Jonkman, M.D.Trade Review`The book is clearly written and well illustrated and should be available in any hospital with an ultrasound department and will prove an ideal introduction and reference book to anyone interested in non-invasive assessment of cerebral vessels.' Journal of Neurology, Neurosurgerey & Psychiatry, March 1988 `The book is very good, and I recommend it for anyone performing cerebral vascular US, whether as an expert or a beginner.' Radiology, April 1988Table of Contents1. Introduction.- 2. Ultrasound physical concepts.- 3. Doppler instrumentation.- 4. Normal anatomy, anatomical anomalies and collateral Pathways of the blood supply to the brain.- 5. Normal blood flow in the arteries.- 6. Normal physiology and pathophysiology of human cerebral blood flow.- 7. Cranial blood flow measurement by means of Doppler ultrasound.- 8. Early carotid lesions and flow disturbances.- 9. Hemodynamics of arterial stenosis.- 10. Vascular bruits.- 11. Free hand Doppler techniques for examination of the extracranial arteries with continuous wave Doppler.- 12. Quantification of carotid stenosis using continuous wave Doppler and spectral analysis.- 13. Vertebral and basilar artery abnormalities.- 14. Doppler imaging.- 15. Clinical application of real-time Doppler color flow mapping of the carotid artery.- 16. Transcranial Doppler diagnosis.- 17. Real-time B-mode imaging of the carotid bifurcation.- 18. Clinical application of high resolution B-scan imaging with pulsed Doppler profiles (10mHz).- 19. Intraoperative Doppler sonography.- 20. Perioperative transcranial Doppler sonography.- 21. Conclusion.- Credit and recognition list.
£40.49
Springer Problems in Peripheral Vascular Disease
Book SynopsisIn writing this short monograph on 'Problems in Peripheral Vascular Disease', I have tried to steer a course between a simplistic dogmatic approach more appropriate to an under graduate text, and a detailed specialist treatise of interest only to vascular surgeons. Although arterial surgery has been performed for centuries, the main indications in the past were to deal with the effects of trauma and aneurysm formation. The development of arterio graphy and the ability to see arterial blocks and stenoses allowed surgeons to carry out increasingly sophistidated operations for an enlarging range of pathological conditions. Even today, arterial surgery continues to develop, and although we are often dealing with the 'surgery of ruins', a successful outcome is just as rewarding for surgeon and patient alike. In this book I have also included a discussion on venous problems including a note about recent developments in direct surgery of the deep veins of the lower limb which could be a re warding field of endeavour for the vascular surgeon. The original descriptions by Buerger and Raynaud are taken from 'Classic Descriptions of Disease' by Ralph H. Major. While reviewing my own surgical practice, I have had the pleasure of reading once again the publications of H.H.G. Eastcott (arterial surgery), J.T. Hobbs (varicose veins), G.L. Hill (Buerger's disease), Adrian Marston (intestinal ischaemia), Martin Bimstingl (vasospastic disorders) and C.H. Hawkes (lumbar canal stenosis).Table of Contents1 Arterial occlusive disease.- Presentation.- Examination and risk factors.- Investigations.- Vasoactive drugs.- Surgical treatment.- 2 The surgical treatment of intermittent claudication.- Assessment.- Aortoiliac disease.- Femoropopliteal reconstruction.- 3 The critically ischaemic limb.- Definition.- Clinical features.- Management.- Results.- 4 When should arteries be dilated?.- Percutaneous transluminal angioplasty.- Technique.- Indications.- 5 Acute ischaemia and arterial embolism.- Thrombosis.- Embolism.- Clinical features.- Management.- 6 Amputation in peripheral vascular disease.- Indications.- Technique.- Results.- Rehabilitation.- 7 What is Buerger’s disease?.- Clinical features.- Prognostic factors.- Management.- 8 Aneurysms.- Pathogenesis.- Aortic aneurysms.- Surgery of leaking aortic aneurysms.- Dissecting aortic aneurysms.- 9 What about sex, doctor?.- Physiology.- Vasculogenic impotence.- Prevention of impotence.- Surgical treatment of vasculogenic impotence.- 10 Vascular surgery of the intestinal tract.- Anatomy.- Pathology.- Chronic intestinal ischaemia.- Acute intestinal ischaemia.- 11 Raynaud’s what?.- Physiology.- Raynaud’s syndrome.- Raynaud’s disease.- Raynaud’s phenomenon.- Assessment and investi-ation.- Treatment.- 12 The diabetic foot.- Pathophysiology.- Clinical presentation.- Assessment.- Management.- 13 Lumbar canal stenosis.- Cauda equina syndrome.- Anatomy.- Clinical features.- Diagnosis.- Treatment.- 14 Varicose veins.- Anatomy.- Physiology.- Classification.- Assessment.- Management.- Recurrent varicose veins.- Superficial thrombophlebitis.- Restless leg syndrome.- 15 Compression sclerotherapy for varicose veins.- Patient selection.- Injection technique.- Complications.- 16 Venous thromboembolism.- Pathogenesis.- Prevention of deep vein thrombosis (DVT).- Clinical features of DVT.- Management of DVT.- Recurrent DVT.- Pulmonary embolism.- 17 The post-thrombotic syndrome.- Clinical features.- Venous outflow obstruction.- Venous reconstructive surgery.- 18 Leg ulcers.- Aetiology.- Clinical features.- Diagnosis.- Management.
£40.49
Springer Problems in Cardiology
Book SynopsisOver several years working in a district general hospital as a physician with a cardiological interest, the common problems in this field are clearer. This knowledge has come through normal out-patient clinic referrals, care of in-patients, and by working in a domiciliary consultative capacity. The problems that concern family physicians nowadays are somewhat different from the problems of two or three decades ago. The accent now is very much on the implications of hypertensive and ischaemic heart disease. Rheumatic fever is rarely seen, though its sequelae may still be discovered. Hence the approach of this book is to the common problems of today in family practice, and the book is not intended to be a reference text book of cardiology. It does not include references because it has been written from personal experience gained from the treatment and management of patients with common cardiac problems. It is hoped that it will be of value primarily to family physicians because it has been written in an attempt to fill a need as measured by the problems that are referred to specialists in the cardiological field. It may prove of value to those medical students and nurses who wish to consider medical problems in a practical way, that is from the ways that cardiac problems present in practice.Table of ContentsPreface.- Foreword.- 1 Presenting symptoms — chest pain.- Skin.- Intercostal muscles and muscles attached to the chest wall.- Ribs and spine.- costo-chondral junctions.- Pleura and diaphragmatic pleura.- The pericardium.- The myocardium.- The aorta.- The oesophagus.- Anxiety and cardiac neurosis.- 2 Ischaemic heart disease.- Myocardial ischaema.- Myocardial infarction.- 3 Hypertension.- Presentation.- General considerations.- Investigations.- Treatment.- Notes on hypotensive drugs.- 4 Cardiac murmurs.- Systolic murmurs.- Diastolic murmurs.- 5 Syncope.- Dysrhythmias.- Valvular heart disease.- Congenital heart disease.- Hypotension.- Other low output states.- Pulmonary embolism.- Cardiac compression.- 6 Breathlessness.- Presenting symptoms.- Acute cardiac failure.- Chronic heart failure.- The signs of heart failure.- Investigations in cardiac failure.- Treatment of cardiac failure.- 7 Infective and invasive processes of the heart.- Pericardium.- Myocardium.- Endocardium.- 8 Electrocardiography.- Particular value of e.c.g. in practice.- Reading and recording the e.c.g..- Some examples of common e.c.g. abnormalities.- 9 Dysrhythmias.- Presenting symptoms.- Supra-ventricular dysrhythmias.- Ventricular causes of dysrhythmia.- other dysrhythmias.- 10 Changing trends in the investigation and treatment of cardiological problems.- Investigations.- Methods of treatment.- 11 Drug therapy in practice.- Diuretics.- The ?-blocking drugs.- Other antidysrhythmic drugs.- Hypotensive drugs.- Anti-anginal drugs.- 12 Present and future problems.- Changing trends of cardiac disease.- Statistics concerning heart disease.- Epidemiology and prevention.- Logistics.
£40.49
Springer Handbook of Cardiac Care
Table of Contents1 Is Heart Disease Preventable?.- 2 Case Finding in General Practice.- 3 The Unexpected Finding on Routine Examination.- 4 The Patient with Chest Pain.- 5 Hypertension.- 6 Cardiac Arrhythmias.- 7 Myocardial Infarction.- 8 Congenital Cardiac Disease.- 9 Long-Term Problems.- 10 Current Investigative Techniques.- 11 Managing Strokes.- 12 Systemic Disorders and the Heart.- 13 Current Therapy.- 14 Future Prospects for the Treatment of Heart Disease.
£40.49
Springer Antihypertensive Drugs Today
Table of Contentsof Volume 4.- I Antihypertensive Drugs: Clinical Pharmacology and Therapeutic Use.- 1. Diuretics.- 1.1 Mechanism of Action.- 1.2 Pharmacokinetics.- 1.3 Clinical Use.- 1.4 Side Effects.- 2. Sympathetic Inhibiting Agents.- 2.1 Ganglion Blocking Agents.- 2.2 Guanethidine and Other Adrenergic Neurone Blocking Drugs.- 2.3 Rauwolfia Alkaloids.- 2.4 Methyldopa.- 2.5 Clonidine.- 2.6 Prazosin.- 2.7 ?-Adrenoceptor Blocking Agents.- 2.8 Labetalol.- 2.9 MAO Inhibitors.- 3. Direct-acting Vasodilators.- 3.1 Hydrallazine.- 3.2 Minoxidil.- 3.3 Diazoxide.- 3.4 Sodium Nitroprusside.- 4. Angiotensin II Analogues and Converting Enzyme Inhibitors.- 5. Treatment Regimens.- 5.1 Mild Hypertension.- 5.2 Moderate to Severe Hypertension.- 5.3 Resistant Hypertension.- 5.4 Hypertensive Emergencies and Presence of Complications.- II Metoprolol: A Review of its Pharmacological Properties and Therapeutic Efficacy in Hypertension.- 1. Animal Pharmacodynamic Studies.- 1.1 ?-Adrenoceptor Blocking Effect.- 1.2 Partial Agonist Activity.- 1.3 ?-Adrenoceptor Selectivity.- 1.4 Antihypertensive Effect.- 1.5 Cardiovascular Haemodynamics in Dogs.- 1.6 Toxicology Studies.- 1.7 Dysmotphology and Reproduction Studies.- 2. Animal Pharmacokinetic Studies.- 2.1 Absorption.- 2.2 Half-Life.- 2.3 Distribution.- 2.4 Metabolism.- 3. Human Pharmacodynamic Studies.- 3.1 Effect on Heart Rate and Cardiac Output.- 3.2 Effect on Blood Pressure.- 3.3 ?-Adrenoceptor Selectivity.- 3.4 Effect on Plasma Renin Activity.- 3.5 Metabolic Effects.- 4. Pharmacokinetic Studies in Man.- 4.1 Absorption.- 4.2 Distribution.- 4.3 Metabolism and Excretion.- 4.4 Plasma Concentration and Clinical Effects.- 5. Therapeutic Trials.- 5.1 Comparison with Placebo.- 5.2 Comparison with Other Drugs.- 5.3 Metoprolol Combined with Other Drugs.- 5.4 Long-term Treatment of Hypertension.- 5.5 Is the Efficacy of Metoprolol in Hypertension Influenced by Frequency of Administration?.- 5.6 What is the Role of Metoprolol in Hypertension?.- 6. Side Effects.- 7. Contraindications.- 8. Precautions.- 9. Dosage.- 10. Overdosage.- III Labetalol: A Review of its Pharmacology and Therapeutic Use in Hypertension.- 1. Pharmacology.- 1.1 Blockade of ?- and ?-Adrenoceptors.- 1.2 Haemodynamic Effects.- 1.3 Effect on Plasma Renin Activity and Plasma Angiotensin II.- 1.4 Effect on Respiratory Function.- 1.5 Animal Toxicological Studies.- 1.6 Mode of Action.- 2. Pharmacokinetics.- 2.1 Absorption.- 2.2 Distribution.- 2.3 Elimination.- 2.4 Plasma Concentration and Clinical Effects.- 2.5 Influence of Disease on Kinetics.- 3. Therapeutic Trials.- 3.1 Open Studies.- 3.2 Placebo-Controlled Trials.- 3.3 Labetalol Compared with a ?-Adrenoceptor Blocker Alone or in Combination with an ?-Adrenoceptor Blocker.- 3.4 Use in Phaeochromocytoma.- 3.5 Intravenous Labetalol in Severe Hypertension.- 3.6 Labetalol in Clonidine Withdrawal Hypertension.- 4. What is the Role of Labetalol in Hypertension?.- 5. Side Effects.- 6. Precautions.- 7. Dosage.- 7.1 Initial Dosage, Oral.- 7.2 Dosage Adjustment.- 7.3 Intravenous Labetalol.- IV Prazosin: A Review of its Pharmacological Properties and Therapeutic Efficacy in Hypertension.- 1. Animal Pharmacodynamic Studies.- 1.1 Mode of Action.- 1.2 Effect on Blood Pressure.- 1.3 Effect on Heart Rate.- 1.4 Effect on Plasma Renin.- 2. Pharmacokinetic Studies in Animals.- 3. Human Pharmacology.- 3.1 Pharmacodynamic Studies.- 3.2 Effect on Renal Function.- 3.3 Effect on Plasma Renin Activity.- 4. Pharmacokinetic Studies in Man.- 4.1 Absorption.- 4.2 Distribution.- 4.3 Elimination.- 4.4 Plasma Concentrations and Clinical Effects.- 4.5 Influence of Disease on Kinetics.- 5. Therapeutic Trials.- 5.1 Prazosin Compared with Placebo.- 5.2 Prazosin Compared with ?-Methyldopa.- 5.3 Prazosin plus a Thiazide Diuretic Compared with Prazosin Alone.- 5.4 Prazosin Compared with Hydrallazine.- 5.5 Prazosin in Combination with other Antihypertensive Drugs.- 5.6 Prazosin in Patients with Renal Disease.- 5.7 Rapid Lowering of Blood Pressure by Prazosin.- 6. Factors Influencing Response to Prazosin.- 6.1 Dosage.- 6.2 Baseline Severity of Blood Pressure and Impaired Renal Function.- 6.3 Duration of Therapy.- 7. What is the Role of Prazosin in the Treatment of Hypertension?.- 8. Side Effects.- 8.1 Postural Effects.- 8.2 Changes in Heart Rate.- 8.3 Skin Reactions.- 8.4 Other Effects.- 8.5 Incidence Compared with ?-Methyldopa.- 8.6 Incidence Compared with Hydrallazine.- 9. Precautions.- 10. Dosage.
£40.49
Springer Heart Transplantation: The Present Status of Orthotopic and Heterotopic Heart Transplantation
Book SynopsisIt is a great pleasure for me to contribute a brief introduction to this volume, to which so many of my colleagues at Groote Schuur Hospital and the University of Cape Town Medical School have contributed. Though considerable advances have been made in preventing or treating the complications of heart transplantation, even today a transplant pro gramme remains a major undertaking for a hospital team. The acquisition of a sufficient number of donor hearts, the maintenance of viability of those hearts, and the prevention, diagnosis and treatment of acute and chronic rejection and infection remain major challenges to those caring for patients undergoing this operation. A transplant programme draws into it medical, surgical, nursing and paramedical staff from all quarters of the hospital and medical school, and requires sustained interest and dedication if patients are to be brought successfully through the procedure. If relevant experimental research is also to be carried out at such a centre, which in my opinion is essential, then an even greater number of highly skilled and creative people is required. A few of the authors of this book have been involved with the Groote Schuur heart transplant programme since its inception in December 1967 with the operation on Louis Washkansky. I am sure that none of them (nor I) had any idea of the public interest this operation would attract.Trade Review`The contributors to this book are to be congratulated in bringing together such a wealth of information on this topic and presenting it in such a balanced and readable way. I believe this book will be essential reading for those considering initiating a heart transplant programme and, indeed, for any interested in progress in this field.' Professor Christiaan N. Barnard (Extract from foreword) Table of Contents1 Experimental development and early clinical experience.- 2 Selection and management of the recipient.- 3 Selection and management of the donor.- 4 Medico-legal aspects.- 5 Donor heart storage.- 6 Immunological aspects.- 7 Anaesthesia and intraoperative care, including cardiopulmonary bypass.- 8 Surgical techniques of orthotopic and heterotopic heart transplantation.- 9 Immediate postoperative care and maintenance immunosuppressive therapy.- 10 Physiology and pharmacology of the transplanted heart.- 11 Pathology of acute rejection.- 12 Diagnosis and management of acute rejection.- 13 Infectious complications.- 14 Malignant neoplasia in the immunocompromised patient.- 15 Psychiatric aspects.- 16 Pathology of chronic rejection.- 17 The management of chronic rejection: retransplantation.- 18 Other complications of transplantation and immunosuppression.- 19 Results of cardiac transplantation and factors influencing survival.- 20 Advantages and disadvantages of heterotopic transplantation.- 21 Transplantation of the heart and both lungs.- 22 The future of heart replacement.- Appendix: Heart transplantation at the University of Cape Town—an overview.
£40.49
Gefen Publishing House Open Hearts: Memoirs of a Cardiac Surgeon
Book Synopsis
£16.99
Fundacion Editorial Juridica Venezolana INTERVENTIONAL AND STRUCTURAL CARDIOLOGY. Legacy
Book Synopsis
£120.00
Springer Verlag, Singapore Catheter Ablation: A Current Approach on Cardiac
Book SynopsisThis book provides cutting-edge theories and techniques for catheter ablation of all kinds of tachyarrhythmias. Catheter ablation has been a main therapeutic method for tachyarrhythmias for more than thirty years now, and countless operations have been successfully performed. It is crucial for electrophysiologists to diagnose arrhythmia mechanisms correctly and to optimize ablation methods, especially in Japan, one of the world’s fastest-aging countries and where many of this book’s authors are based.The volume is divided into eight parts. The first three parts present the basic theories and novel insights essential to diagnosing and performing catheter ablations. In turn, the latter five parts highlight practical ablation methods in the context of frequently encountered arrhythmias cases, as well as rare ones such as chanellopathies. Written for electrophysiologists who treat patients with cardiac arrhythmias, the book offers readers essential tips and tricks for the optimal treatment of arrhythmias.Table of ContentsPart I Cardiac Anatomy for Catheter Ablation .- 1. Atrial and Atrio-Ventricular Junctional Anatomy: Myocardial orientation and its heterogeneity.- 2. Anatomy of Aorta, Pulmonary artery and Ventricles .- Part II Techniques and Interpretation to Diagnose the Mechanism of Supraventricular Tachycardias.- 3. Entrainment pacing: A diagnostic tool for reentrant tachycardia and its application for catheter ablation.- 4. Para-Hisian Pacing.- 5. Entrainment Pacing for Differential Diagnosis of Supraventricular Tachycardias.- Part III Special Sites for Ablation.- 6. Aortic Sinus Cusps for Catheter Ablation of Supraventricular and Ventricular Arrhythmias.- 7. Coronary Sinus for Ablation of Ventricular Tachyarrhythmia and Supraventricular.- 8. Vein of Marshall Chemical Ablation of Atrial Tachyarrhythmias.- Part IV Catheter Ablation of Atrial Tachycardias and Flutter.- 9. Cavo-tricuspid Isthmus Dependent Atrial Flutter.- 10. Uncommon Atrial Flutter.- 11. Adenosine-sensitive Atrial Tachycardia .- 12. Focal Atrial Tachycardia.- 13. Catheter Ablation of Atrial Tachycardia Following Catheter and Surgical Ablation of Atrial Fibrillation.- Part V Catheter Ablation of Atrial Fibrillation.- 14. Pulmonary vein isolation: Radiofrequency energy.- 15. Pulmonary vein isolation: cryoballoon ablation.- 16. Radiofrequency HotBalloon Ablation.- 17. Catheter Ablation of Posterior LA Isolation: Box Isolation.- 18. Isolation of Superior Vena Cava.- 19. Catheter Ablation of Non-Pulmonary Vein Foci20. Stepwise Ablation for Persistent Atrial Fibrillation.- 21. Substrate ablation of persistent AF.- 22. Autonomic Ganglionated Plexi Ablation in Patients with Atrial Fibrillation.- Part VI Catheter Ablation of Atrio-Ventricular Nodal Tachycardias.- 23. Slow Pathway Ablation for Atrioventricular Nodal Reentrant Tachycardia.- 24. Ablation of Superior Slow Pathway in Atypical Fast-Slow Atrioventricular Nodal Reentrant Tachycardia.- 25. Retrograde Fast Pathway Ablation in Atrio-ventricular Nodal Reentrant Tachycardia.- Part VII Catheter Ablation of Accessory Pathways.- 26. Free Wall Atrio-Ventricular Accessory Pathways.- 27. Posteroseptal Atrio-Ventricular Accessory Pathways.- 28. Catheter ablation of antero-septal (supero-paraseptal) and mid-septal (true septal) accessory pathways.- 29. Atriofascicular Accessory Pathways.- 30. Nodofascicular/ Nodoventricular Accessory Pathway.- Part VIII Catheter Ablation of Ventricular Tachycardias.- 31. Outflow Tract Ventricular Tachycardias and Premature Ventricular Contractions - ECG based prediction of Origin Sites -.- 32. Idiopathic Left Fascicular Ventricular Tachycardia.- 33. Bundle Branch Reentrant Ventricular Tachycardia.- 34. Papillary Muscle Ventricular Tachycardia.- 35. Ventricular Tachycardia in Non-ischemic Cardiomyopathy.- 36. Ventricular Tachycardia in Ischemic Heart Disease.- 37. Ablation of Brugada Syndrome.- 38. Ablation of Catecholaminergic Polymorphic Ventricular Tachycardia.- 39. Epicardial Ablation for Ventricular Tachycardia.- 40. Ablation of Electrical Storm.
£119.99
World Scientific Publishing Co Pte Ltd Evidence-based Clinical Chinese Medicine - Volume
Book SynopsisThe fifteenth volume of the Evidence-based Clinical Chinese Medicine series examines the management of chronic heart failure with Chinese medicine using a 'whole evidence' approach. Readers are provided with an overview of the current management of chronic heart failure with both conventional medicine and contemporary Chinese medicine. This is followed by a detailed analysis of how chronic heart failure was viewed and managed in past eras.Evidence from clinical studies is systematically reviewed and analysed to evaluate the potential benefits of Chinese herbal medicines and other Chinese medicine treatments for people with chronic heart failure. A review of experimental studies highlights some of the mechanisms of actions of a selection of the most frequently used Chinese herbs. The outcomes of analyses are presented and discussed in the final chapter and we identify implications for contemporary practice and promising areas for future research.This book provides clinicians and students in the fields of Chinese and integrative medicine with a comprehensive synthesis of traditional and contemporary knowledge that can inform clinical decision-making.
£66.50
World Scientific Publishing Co Pte Ltd Uncertainty, Decision-making And Team Work In
Book SynopsisThe Relational Medicine project is growing. In 2014 we published our practice framework 'Relational Medicine — Personalizing Modern Healthcare: The Practice of High-Tech Medicine As A RelationalAct'. Building on this foundation, we now present a cutting-edge and fully developed single case recording analysis of consecutive encounter interactions in a dramatically accelerating life-and-death decision-making situation in the high-tech medical practice of Advanced Heart Failure during which practitioners, patient, and family face multiple uncertainties as the decision-making process unfolds and the patient's condition deteriorates.We show how a multi-professional team including a cardiologist, cardiac surgeon, critical care unit nurse and fellows discuss life-prolonging options with their patient and family. We make visible the essential roles of each multi-disciplinary team member in helping frame for the patient and family what is going on and the changing options while attending to the patient's PERSON-soul-mind-body-HOOD.In bringing different data, perspectives, and facets of understanding to bear, this book offers a novel approach to studying high-tech medical care grounded in Federica Raia's Relational Ontology framework of understanding everyday practice. Using a micro-ethnographic data analysis and a participatory research strategy, we unravel a heretofore unrecognized universe of practice themes and present suggestions for medical education and training aimed at continuous practice improvement.
£66.50
Springer Verlag, Singapore Cardiovascular 3D Printing: Techniques and
Book SynopsisThis book offers readers a comprehensive introduction to the techniques and application of 3D printing in cardiovascular medicine. To do so, it addresses the history, concepts, and methods of 3D printing, choice of printing materials for clinical purposes, personalized planning of cardiac surgery and transcatheter interventions with patient-specific models, enhancement of patient-physician communication, simulation of endovascular procedures, and advances in 3D bio-printing. The book particularly focuses on the application of 3D printing to improve the efficacy and safety of cardiac interventions, and to promote the realization of precision medical care. The book gathers contributions by an international team of experts in the field of cardiovascular medicine, who combine the latest findings with their own practical experience in using 3D printing to support the diagnosis and treatment of a wide range of cardiovascular diseases. They present in-depth discussions in the fields of congenital heart disease, valvular disease, coronary artery disease, cardiomyopathy, left atrial appendage occlusion, cardiac tumors and vascular diseases.Table of ContentsHistory of 3D printing in cardiovascular diseases.- Methods of 3D printing in cardiovascular diseases.- Material selection of 3D printing in cardiovascular diseases.- Clinical application of 3D printing in cardiovascular diseases.- 3D printing in congenital cardiac diseases.- 3D printing in valve diseases.- 3D printing in LAAO.- 3D printing in coronary diseases.- 3D printing in cardiac tumour.- 3D printing in cardiomyopathy.- 3D printing in large vascular diseases.- Perspective and advancement of 3D printing.
£85.49
Springer Verlag, Singapore Low Invasive Pediatric Cardiac Surgery
Book SynopsisThis book demonstrates the significance of minimally invasive extracorporeal circulation and reduced time as two of the most important factors for pediatric cardiac surgery and early postoperative recovery. The content is divided into three major thematic sections: low invasiveness; pitfalls and countermeasures before, during and after operations; and suggestions on time-saving and team building. Abundant figures aid in comprehension, while videos of the surgery offer practical insights for readers at all levels. Advances in extracorporeal circulation devices and management have led to new clinical problems such as decreased perfusion pressure, high pressures in oxygenators, and changes in acid-base equilibrium. The book explains these problems both clinically and experimentally, and describes countermeasures. Low Invasive Pediatric Cardiac Surgery provides valuable evidence and practical suggestions for all surgeons, perfusionists, scrub-nurses, and anesthesiologists who are engaged in pediatric cardiac surgery. It will also appeal to pediatric cardiologists and medical device manufacturers. The book is intended to share the author’s experience and actual data with readers who have clinical experience, and to help prepare beginners. Table of Contents
£66.49
World Scientific Publishing Co Pte Ltd Fibroblast Growth Factors: Biology And Clinical
Book SynopsisThe fibroblast growth factor (FGF) family of ligands and the corresponding family of FGF receptor tyrosine kinases comprise one of the most versatile and diverse growth factor signaling families in vertebrates, found virtually in every tissue and cell type where they regulate metabolic and physiologic function, maintain tissue homeostasis, and mediate injury response, tissue repair, and regeneration. As a result, FGFs play critical roles in a wide variety of normal biological and abnormalities in FGF signaling can lead to a variety of disease states from developmental malformations, to atherosclerosis, pulmonary hypertension and cancer among many others. A thorough understanding of this system is necessary for critical insights into both normal and disease biology and is essential to development of rationale therapeutic strategies aimed at treatment of FGF-dependent diseases states.Recent years have seen advances in our understanding of FGFs role in endothelial and, more general, vascular biology, the subject of this book. In particular, FGFs have been implicated in the maintenance of vascular homeostasis and control of blood vessel permeability while aberrant FGF signaling has been shown to be central to the development of pulmonary hypertension, and endothelial-to-mesenchymal transition, a process implicated in the development of atherosclerosis. Finally, FGFs ability to stimulate blood vessel growth has been explored in therapeutic angiogenesis approaches.With this in mind, the present monograph is structured to provide comprehensive information to a reader interested in FGFs in general and vascular biology in particular. To this end, we explore everything from the structure and signaling of FGFs and their receptors (Chapters 1, 2 and 3) to their role in the regulation of vascular homeostasis (Chapter 4) and cardiovascular diseases (Chapters 5 and 6). We then address new developments in FGF therapeutics (chapter 7) and explore FGF biology in the epithelium (Chapter 8) thereby providing a complete analysis of this growth factor family biology in two closely related but distinctly different environments — endothelium and epithelium. Finally, we examine FGF biology in eye disease and in cancer.It is our hope that this comprehensive treatment of FGF vascular biology and its application will provide the reader with the accurate and timely summary of this rapidly moving field.
£110.70
World Scientific Publishing Co Pte Ltd Vascular Smooth Muscle: Structure And Function In
Book SynopsisThis book presents key concepts in the structure and function of vascular smooth muscle cells in health and disease. Supplemental reading may be drawn from the extensive references listed at the end of each chapter. Vascular smooth muscle cell is the major cell type in blood vessels. Dysfunction of vascular smooth muscle cells is an important cause of vascular diseases, for example, atherosclerosis, hypertension, and circulatory shock. Vascular smooth muscle cells are phenotypically plastic, capable of switching between two major phenotypes — contractile/differentiated phenotype and invasive/proliferative phenotype in response to environmental clues. Chapter 1 introduces the major areas of research presented in this monograph. Chapters 2 to 4 address the structure and function of the contractile/differentiated phenotype of vascular smooth muscle cell. Chapters 5 and 6 address the developmental basis of vascular smooth muscle cell phenotype and structure and function of podosomes (invasive organelles) in the invasive/proliferative phenotype of vascular smooth muscle cell. Chapters 7 to 9 address the role of vascular smooth muscle cell dysfunction in vascular diseases — atherosclerosis, hypertension, and circulatory shock.
£100.80
World Scientific Publishing Co Pte Ltd Cardioprotective Natural Products: Promises And
Book SynopsisCardioprotective Natural Products: Promises and Hopes focuses on the recent advances in the research of bioactive natural products with cardioprotective potential against various cardiovascular diseases/disorders. The aim of this book is to underline the promise and future hope in bioactive natural molecules, herbal formulations, natural dietary supplements and related materials in the prevention and cure of cardiovascular diseases in a scientific way.This book, which comprises a variety of about 9 chapters written by active researchers and leading experts, brings together an overview of current discoveries and trends in this field. This volume is also an outstanding source of information with regard to the industrial application of natural products for medicinal purposes. The broad interdisciplinary approach adopted in this book ensures that it is much more interesting to scientists deeply engaged in the research and/or use of bioactive natural products. It will serve not only as a valuable resource for researchers in their own fields to predict promising leads for developing pharmaceuticals to prevent and treat disease manifestations, but will hopefully also motivate young scientists to engage in the dynamic field of natural products research.
£101.70
World Scientific Publishing Co Pte Ltd Hemodynamics And Mechanobiology Of Endothelium
Book SynopsisThe book represents a paradigm shift from the traditional static model of investigation of oxidative biology to the dynamic model of vascular oxidative stress. The investigation of vascular biology and cardiovascular medicine is made possible by the use of fluid dynamics, molecular signaling, genomic approach, tissue engineering, stem cell biology, and microfluidics. This is the first book to target a wide readership from academia to industry and government agencies in the field of cardiovascular diseases.Table of ContentsMechanosensors; Mechanosignal Transduction; Flow-Dependent Regulation of Endothelial Cell Biology and Pathobiology; Flow and Vascular Diseases in Vivo; Flow Models: In Vitro and In Vivo; Hemodynamics in Cardiovascular Systems; Emerging Areas.
£108.00
World Scientific Publishing Co Pte Ltd Antioxidants And Stem Cells For Coronary Heart
Book SynopsisThis book covers two known controversial topics — antioxidants and stem cells as therapies to treat coronary heart disease. Aiming to provide college-educated but not scientifically trained readership with a wealth of information about these two cutting-edge technologies, Antioxidants and Stem Cells for Coronary Heart Disease is written with minimum scientific terminology. Basic science studies and clinical trials regarding stem cells and antioxidants are discussed and peppered with anecdotes to make them understandable and entertaining to the laymen.Table of ContentsAntioxidants and Stem Cells for Coronary Heart Disease: An Introduction; LDL Oxidation: Briefly; Acetylation of LDL; Free Radicals; The Oxygen Paradox; Retrolental Fibroplasia from 1956 to 1972. The Quiet Time; The Second Epidemic of Retrolental Fibroplasia; Cytokines and Chemokines; LDL Oxidation by Free Radicals: In Detail; Two Other Ways to Oxidize LDL: Lipoxygenase and Nitric Oxide; What is the Raison D'etre for Oxidized LDL?; Fatty Streaks and Foam Cells; Embryonic Stem Cells; Adult Stem Cells; Transgenic Mice; Part Two: The Treatment of Coronary Heart Disease with Antioxidants: An Introduction; The Mediterranean Diet; Wine, Beer and Spirits; Trans Fats; Vitamin C; Beta Carotene; Vitamin E; Probucol; Stem Cells for the Heart: Hope or Hype?; Treatment of Coronary Heart Disease in 2020: A Perspective.
£111.60
World Scientific Publishing Co Pte Ltd Heart Regeneration: Stem Cells And Beyond
Book SynopsisInjured mammalian hearts do not regenerate but scar. This is a major medical problem, as ischemic heart disease is among the leading causes of morbidity and mortality worldwide. Essential clues for human heart repair are uncovered when zebrafish and newt are found to regenerate cardiac muscle after injury.This book presents the major advances of the last decade in the field of cardiac regeneration. These recent advances include: demonstration that zebrafish, a genetically tractable system, can regenerate heart; the identification of several new stem cell populations in the heart; demonstration that stem cells can be used to improve heart function; and demonstration that induction of cardiomyocyte proliferation is a realistic future option to repair injured hearts. This book also provides detailed reviews of the research on model organisms capable of heart regeneration as well as innovative translational research to achieve regeneration in mammals, that comprises work on blood born stem cells, endogenous cardiac stem cells, paracrine factors, reawakening of cardiomyocyte proliferation, and bioengineering. More importantly, the book, in the concluding chapter, dovetails the studies with a comprehensive overview of clinical trials.Table of ContentsIntroduction into Cardiac Disease; Cardiac Growth During Development; Does Heart Regeneration Occur?; Repopulation of the Heart with New Cardiomyocytes; What is the Paracrine Effect of Stem Cells?; How to Create an Artificial Heart Ex Vivo?; The Complexity of Organ Regeneration; Clinical Trials.
£112.50
World Scientific Publishing Co Pte Ltd 100 Challenges In Cardiology
Book Synopsis100 Challenges in Cardiology comprises one hundred well-illustrated clinical scenarios covering a wide spectrum of cardiology cases — hypertension, stable and unstable angina, non-ST elevation and ST-elevation myocardial infarction, coronary intervention, percutaneous aortic and mitral valve treatment, ASD closure, complications of MI, valvular heart disease, pericardial disease, cardiomyopathies, HOCM ablation, haemodynamic assessment in catheterisation laboratory, aortic dissection, infective endocarditis and its complications. Cardiac pacing, arrhythmia diagnosis and management, electrophysiology, CT and MRI scans, and transthoracic and transoesophageal echocardiography images are also included for interpretation.This book will serve as an ideal study aid for medical students and junior doctors who are preparing for their clinical examinations in medicine as it presents the relevant investigations corresponding to each case in an interesting and easy-to-read Q&A format concerning diagnosis and management. This text will also be particularly useful for clinical fellows and specialist senior house officers and registrars who are training in cardiology and its subspecialties. By solving the problems posed by these challenging cases, the reader will gain additional knowledge as well as extra practice in diagnosis and treatment strategies in this exciting specialty of cardiology.
£53.20
Pan Stanford Publishing Pte Ltd Atherosclerosis: Treatment and Prevention
Book SynopsisIn recent years, the understanding of the pathophysiological processes of atherosclerosis, a chronic inflammatory disease of the vessel wall being the leading cause for mortality in industrial countries, has tremendously increased. The feasibility of translating such knowledge to novel therapeutic approaches is currently being explored at various levels. This book highlights advances in atherosclerosis and links these to relevant therapeutic strategies. It compiles and details cutting-edge research in cardiovascular medicine from internationally renowned authors. Table of ContentsNovel approaches in treatment of atherosclerosis. Chemokines as therapeutic targets of atherosclerosis. MIF antagonism as a therapeutic approach to atherosclerosis. Peptide-based vaccination strategies to promote Treg- or antibody-mediated atheroprotection. Modulation of prostanoids in the treatment of atherosclerosis. Stabilization of mast cells for taming vulnerable plaques. HDL, ABC transporters, and cholesterol efflux as therapeutic targets in atherosclerosis. Role of selective phospholipase A2 inhibition in the treatment of atherosclerosis. Modulation of the rennin-angiotensin system in atherosclerosis. Role of matrix metalloproteases as targets for the prevention of atherosclerosis. Probucol-derivates in the treatment of atherosclerosis. Interference with apoptosis and ER stress in the treatment of atherosclerosis. MicroRNAs in the pathogenesis and therapy of atherosclerotic vascular disease. Neutrophils and their granule proteins in the treatment of atherosclerosis. Platelets in the treatment of atherosclerosis. Costimulatory molecules in the treatment of atherosclerosis.
£126.00
World Scientific Publishing Co Pte Ltd Cardiac Drug Safety: A Bench To Bedside Approach
Book SynopsisEnsuring the safety of new medical products remains a major challenge for the pharmaceutical industry. Cardiac safety, particularly drug-induced heart rhythm abnormalities, remains an important cause of pipeline attrition and has resulted in countless major product recalls or label changes. The risk of encountering this major adverse event continues to shape the drug development and regulatory landscape.Extensive research over the past decade has shed light on the root causes of arrhythmias that are triggered by medications and has helped drive, and optimize, drug safety testing. However, current cardiac safety platforms have several limitations and there remains a pressing unmet need to improve the predictive power of today's drug safety tests.Fundamental to addressing the problem of drug-induced arrhythmias, and to reducing the impact of this safety signal on drug development, is a complete understanding of how these events may arise, what cardiac safety tests are currently used, and what opportunities there are to enhance patient safety and reduce the risk of detecting cardiac toxicity in later stages of product commercialization. By introducing the reader to these core concepts, this book delivers key insight into the increasingly important and dynamic field of cardiac safety.Table of ContentsChallenges Facing the Pharmaceutical Industry in the 21st Century; The Cellular Basis of Cardiac Electrophysiology; Clinical Arrhythmia Syndromes; The Mechanisms Underlying Cardiac Arrhythmias; The Mechanisms Underlying Drug-Induced Arrhythmias; Assessing Cardiac Safety in Drug Development; Pediatric Cardiac Safety; Drug-Induced Atrial Fibrillation; Navigating the Future Path of Cardiac Drug Safety.
£65.55
Pan Stanford Publishing Pte Ltd Myocardial Tissue Engineering
Book SynopsisRegenerative therapy has rapidly developed as one of the most promising treatments for patients suffering from severe heart failure. Autologous bone marrow-derived cells and cardiac stem cells have been clinically applied for cell injection therapy for heart failure. As a next-generation therapy, tissue-engineered myocardial-patch transplantation has also been started clinically. As further advanced therapy, several researchers have started to fabricate three-dimensional beating myocardial tissues. One of the main problems in myocardial tissue engineering is neovascularization within the tissues during scale-up. Several innovative technologies have been developed to overcome the vascularization problem.This book broadly summarizes myocardial tissue engineering and regenerative medicine, which consists of myocardial cell sources, cell therapy for damaged hearts, and tissue engineering technologies for fabricating beating hearts. With respect to myocardial cell source, it focuses on cardiac cells differentiated from embryonic stem and induced pluripotent stem cells. It describes the remarkable results obtained in the past and the present to control neovascularization and presents the future challenges in myocardial tissue engineering research. Table of ContentsIntroduction. Cell Sources for Myocardial tissue Engineering. Cell therapy for Myocardial Infarction in Clinical Trials. Tissue Engineering. Myocardial Patches. Pulsatile Myocardial Tissue Engineering. Future Developments.
£103.50
World Scientific Publishing Co Pte Ltd Clinical Electrocardiography (Fourth Edition)
Book SynopsisSince the publication of the 3rd Edition 17 years ago, progress has been truly remarkable in all areas of electrocardiography. Five of the seven chapters in this 4th Edition have been extensively revised. Out of the total of 125 ECGs, 65 are new. Each ECG is crisp and clear and all the abnormalities are highlighted by arrows for easy recognition and understanding. This book is the culmination of the author's 45 years of experience in the teaching of electrocardiography to coronary care unit nurses, medical undergraduates, postgraduates, interns, residents, senior residents and above. As the title of the book implies, the approach to the subject has been entirely from the viewpoint of a clinician. Hence, clinical-electrocardiographic correlations have been emphasized simply and succinctly throughout the text.Table of ContentsForeword; Preface; Acknowledgements; The Normal Electrocardiogram; Ischaemic Heart Disease; Miscellaneous Conditions; Cardiac Arrhythmias; Supraventricular Arrhythmias; Ventricular Arrhythmias; Bundle Branch Block, Hemiblock and Atrioventricular (AV) Block; Index;
£45.60
World Scientific Publishing Co Pte Ltd Coronary Ct Angiography In The Quantitative
Book SynopsisThis book provides a comprehensive overview of the author's work which includes significant developments of coronary CT angiography in the diagnosis of coronary plaques. The main contributions of the book lie in the following areas: both 2D and 3D analysis of coronary plaques with coronary CT angiography, diagnostic value of coronary CT angiography with use of different multislice CT scanners, quantitative analysis of coronary plaques in terms of lumen assessment, and bifurcation angle analysis, in particular, the diagnostic performance of coronary CT angiography in calcified plaques, and finally, hemodynamic analysis of plaques with regard to the effects of plaques on coronary blood flow, and CT-derived fractional flow reserve (FFRCT).
£85.50
Springer Manual of Echocardiography for Congenital Heart Diseases
Book Synopsis1. Echocardiographic Principles.- 2. Echocardiographic Views.- 3. Segmental Anatomy and Cardiac Malpositions.- 4. Shunt Lesions.- 5. Atrioventricular Septal Defects.- 6. Right Ventricular Inflow Anomalies.- 7. Right Ventricular Outflow Tract Anomalies.- 8. Anomalies of Pulmonary Veins, Left Atrium and Left Ventricular Inflow.- 9. Left Ventricular Outflow Tract Anomalies.- 10. Tetralogy of Fallot.- 11. Transposition of Great Arteries (TGA).- 12. Single Functional Ventricle.- 13. Systemic Venous Anomalies.- 14. Coronary Artery Anomalies.- 15. Congenital Cardiomyopathies, Pulmonary Hypertension, and Other Anomalies.- 16. Diagnostic Probabilities at the Bedside.
£89.99
Springer Transesophageal Echocardiography in Pediatric
Book SynopsisOverview of Echocardiography for Pediatric Congenital Heart Diseases.- TEE for Pediatric CHD Surgery and Catheter Intervention.- Septal Defects.- Valvular Abnormality.- Vascular Abnormalities.- Chamber Defect.- Other Congenital Heart Diseases.- Septal Defects.- Fistula and Collateral.- Postoperative Residual Defects.- Hybrid Procedures.- Valvular Abnormality.
£80.99
Broken Hill Publishers Ltd Emergency Cardiology: A Practical Guide
Book Synopsis
£38.46
Nova Science Publishers Inc Horizons in World Cardiovascular Research. Volume
Book Synopsis
£177.59
Post Hill Press Cardiac Cowboys: The Heroic Invention of Heart
Book SynopsisCardiac Cowboys is the dramatic story of five deeply flawed geniuses who together—and in competition with each other—invented open-heart surgery against all conventional medical wisdom and saved millions of lives.A decade after World War II, there was still no such thing as open-heart surgery, and yet half a million Americans were dying from heart disease every year. One in a hundred children would suffer and die from congenital heart disease as well, and doctors did little other than predict their deaths. After the first daring operation in 1954 and through the next three decades, five heroic surgeons braved the scorn of their peers, withstood fierce desperation, and faced possible death in order to devise procedures that would save overwhelming numbers of those doomed children and provide hope for a new life to all manner of heart-failing individuals. Devising and mastering heart transplants and bypass surgery, they invented artificial heart valves, the lifesaving pacemaker, and worked toward the holy grail of an artificial heart as their private and professional lives imploded. The story of the Cardiac Cowboys, their outsized personalities, and often self-destructive behavior is a saga more thrilling and exhilarating than fiction.
£23.19
Nova Science Publishers, Inc. Horizons in World Cardiovascular Research. Volume
Book Synopsis
£177.59
