Biophysics Books

264 products


  • Biomechanics For Dummies

    John Wiley & Sons Inc Biomechanics For Dummies

    3 in stock

    Book SynopsisA thorough explanation of the tenets of biomechanics At once a basic and applied science, biomechanics focuses on the mechanical cause-effect relationships that determine the motions of living organisms. Biomechanics for Dummies examines the relationship between biological and mechanical worlds.Table of ContentsIntroduction 1 About This Book 1 Foolish Assumptions 2 Icons Used in This Book 3 Beyond the Book 3 Where to Go from Here 4 Part I: Getting Started with Biomechanics 5 Chapter 1: Jumping Into Biomechanics 7 Analyzing Movement with Biomechanics 7 Mechanics 8 Bio 9 Expanding on Mechanics 10 Describing motion with kinematics 11 Causing motion with kinetics 13 Putting Biomechanics to Work 14 Chapter 2: Reviewing the Math You Need for Biomechanics 15 Getting Orientated 16 Brushing Up on Algebra 17 Following the order of operations 17 Defining some math operations 19 Isolating a variable 20 Interpreting proportionality 22 Looking for the Hypotenuse 23 Using the Pythagorean theorem 24 De-tricking trigonometric functions: SOH CAH TOA 26 Unvexing Vector Quantities 31 Resolving a vector into components 33 Composing a vector from components 35 Chapter 3: Speaking the Language of Biomechanics 37 Measuring Scalars and Vectors 38 Standardizing a Reference Frame 39 Directing your attention to locations of the body 40 Referencing planes and axes 40 Describing Movement: Kinematics 42 Typecasting motion: Linear, angular, and general 42 Describing how far: Distance and displacement 43 Describing how fast: Speed and velocity 44 Changing velocity: Acceleration 45 Pushing and Pulling into Kinetics 45 Forcing yourself to understand Newton’s laws of motion 47 Using the impulse–momentum relationship 49 Working with Energy and Power 49 Mechanical work 49 Mechanical energy 50 Mechanical power 51 Turning Force into Torque 51 Dealing with Measurement Units 51 Using the Neuromusculoskeletal System to Move 52 The skeletal system 53 The muscular system 53 The nervous system 55 Part II: Looking At Linear Mechanics 57 Chapter 4: Making Motion Change: Force 59 Pushing and Pulling: What Is Force? 59 Working with Force Vectors 65 Using the force components to find the resultant 66 Resolving a force into components 68 Classifying Forces 69 Contact and noncontact forces 69 Internal and external forces 70 Feeling the Pull of Gravity 74 Slipping, Sliding, and Staying Put: Friction Is FμN 76 Materials do matter: The coefficient of friction ( μ ) 80 Squeezing to stick: Normal reaction force (N) 81 Chapter 5: Describing Linear Motion: Linear Kinematics 83 Identifying Position 84 Describing How Far a Body Travels 85 Distance.85 Displacement 86 Describing How Fast a Body Travels 88 Speed 89 Velocity 90 Momentum 92 Speeding Up or Slowing Down: Acceleration 92 Constant acceleration 95 Projectile motion 95 Chapter 6: Causing Linear Motion: Linear Kinetics 103 Clarifying Net Force and Unbalanced Force 103 Newton’s First Law: The Law of Inertia 106 Newton’s Third Law: The Law of Equal and Opposite Action–Reaction 107 Newton’s Second Law: The Law of Acceleration 109 Deriving the impulse–momentum relationship from the law of acceleration 112 Applying the impulse–momentum relationship for movement analysis 114 Chapter 7: Looking At Force and Motion Another Way: Work, Energy, and Power 119 Working with Force 120 Energizing Movement 122 Kinetic energy 123 Potential energy 124 Conserving Mechanical Energy 128 Powering Better Performance 130 The Work–Energy Relationship 131 Part III: Investigating Angular Mechanics 137 Chapter 8: Twisting and Turning: Torques and Moments of Force 139 Defining Torque 140 Lining up for rotation: The moment arm of a force 141 Calculating the turning effect of a force 142 Measuring Torque 144 Muscling into torque: How muscles serve as torque generators 145 Resisting torque: External torques on the body 148 Expanding on Equilibrium: Balanced Forces and Torques 149 Locating the Center of Gravity of a Body 152 Chapter 9: Angling into Rotation: Angular Kinematics 157 Measuring Angular Position 157 Describing How Far a Body Rotates 160 Angular distance 161 Angular displacement 162 Describing How Fast a Body Rotates 163 Angular speed.163 Angular velocity 164 Speeding Up or Slowing Down: Angular Acceleration 165 Relating Angular Motion to Linear Motion 167 Angular displacement and linear displacement 168 Angular velocity and linear velocity 169 Angular acceleration and linear acceleration 171 Chapter 10: Causing Angular Motion: Angular Kinetics 173 Resisting Angular Motion: The Moment of Inertia 174 The moment of inertia of a segment174 The moment of inertia of the whole body 178 Considering Angular Momentum 180 Angular momentum of a rigid body 180 Angular momentum of the human body when individual segments rotate 181 A New Angle on Newton: Angular Versions of Newton’s Laws 181 Maintaining angular momentum: Newton’s first law.182 Changing angular momentum: Newton’s second law 186 Equal but opposite: Newton’s third law189 Changing Angular Momentum with Angular Impulse 191 Chapter 11: Fluid Mechanics 193 Buoyancy: Floating Along 193 Considering Force Due to Motion in Fluid 197 Causing drag in a fluid 198 Causing lift in a fluid 201 Part IV: Analyzing the “Bio” of Biomechanics 205 Chapter 12: Stressing and Straining: The Mechanics of Materials 207 Visualizing Internal Loading of a Body 208 Applying Internal Force: Stress 210 Normal stress 212 Shear stress 217 Responding to Internal Force: Strain 219 Determining tensile strain 221 Determining compressive strain 221 Determining shear strain 222 Straining from Stress: The Stress–Strain Relationship 223 Give and go: Behaving elastically 224 Give and stay: Behaving plastically 224 Chapter 13: Boning Up on Skeletal Biomechanics 227 What the Skeletal System Does 228 How Bones Are Classified 228 The Materials and Structure of Bones 230 Materials: What bones are made of 231 Structure: How bones are organized 232 Connecting Bones: Joints 234 Immovable joints 234 Slightly movable joints 234 Freely movable joints 235 Growing and Changing Bone 237 Changing bone dimensions 238 Stressing bone: The effects of physical activity and inactivity 239 Chapter 14: Touching a Nerve: Neural Considerations in Biomechanics 247 Monitoring and Controlling the Body: The Roles of the Nervous System 248 Outlining the Nervous System 248 The central nervous system 250 The peripheral nervous system 250 Zeroing In on Neurons 251 Parts of neurons 251 Types of neurons 251 Controlling Motor Units 259 Motor unit recruitment 261 Rate coding 261 Chapter 15: Muscling Segments Around: Muscle Biomechanics 263 Characterizing Muscle 263 Seeing How Skeletal Muscles Are Structured 265 The macrostructure of muscles 266 The microstructure of muscle fibers.268 Comparing Types of Muscle Activity 270 Isometric activity 271 Concentric activity 272 Eccentric activity 272 Producing Muscle Force 274 Relating muscle length and tension 274 Relating muscle velocity and tension277 Stretching before Shortening: The Key to Optimal Muscle Force 279 Part V: Applying Biomechanics 283 Chapter 16: Eyeballing Performance: Qualitative Analysis 285 Serving as a Movement Analyst 286 Evaluating the Performance 287 Identifying the goal of the movement 287 Specifying the mechanical objective 289 Determining whether the goal has been reached 290 Troubleshooting the Performance 293 Constraints on performance 293 Technique errors 294 Pitching by the phases 298 Intervening to Improve the Performance 302 Adapting the constraints on throwing performance 302 Refining technique 303 Chapter 17: Putting a Number on Performance: Quantitative Analysis 305 Converting Continuous Data to Numbers 305 Measuring Kinematics: Motion-Capture Systems 306 Collecting kinematic data 307 Processing kinematic data 308 Measuring Kinetics: Force Platform Systems 310 Collecting kinetic data 310 Processing kinetic data 312 Recording Muscle Activity: Electromyography 313 Collecting the electromyogram 314 Processing the electromyogram 315 Chapter 18: Furthering Biomechanics: Research Applications 319 Exercising in Space 319 Repairing the Anterior Cruciate Ligament 320 Running Like Our Ancestors 322 Protecting Our Beans: Helmet Design 324 Balancing on Two Legs: Harder Than You Think 326 Chapter 19: Investigating Forensic Biomechanics: How Did It Happen? 329 Collecting Information for a Forensic Biomechanics Analysis 330 Witness accounts 330 Police incident investigation reports 331 Medical records 331 Determining the Mechanism of Injury 332 Evaluating Different Scenarios 335 Ending up on the far side of the road 335 Landing in water with a broken jaw 336 Part VI: The Parts of Tens 339 Chapter 20: Ten Online Resources for Biomechanics 341 The Exploratorium 341 The Physics Classroom 341 Coaches Info 342 Textbook-Related Websites 343 Topend Sports 343 Dr. Mike Marshall’s Pitching Coach Services 343 Waterloo’s Dr. Spine, Stuart McGill 344 Skeletal Bio Lab 345 Biomch-L 345 American Society of Biomechanics 346 Chapter 21: Ten Things You May Not Know about Biomechanics 347 Looking at How Biomechanics Got Its Start 347 Adding Realism to Entertainment 348 Developing Safer Motor Vehicles 348 Improving the On-Shelf Quality of Fruits and Vegetables 349 Fitting Footwear to the Activity 350 Banning Biomechanically Improved Sport Techniques 351 Re-Creating Dinosaurs 352 Designing Universally and Ergonomically 352 Giving a Hand to Prosthetics Design 353 Losing Weight to Help Your Joints 354 Chapter 22: Ten Ways to Succeed in Your Biomechanics Course 355 Go to Class and Ask Questions 355 Read the Textbook 356 Do the Problems and Review Questions at the End of the Chapter 357 Create Flashcards 357 Go to Office Hours 358 Form a Study Group with Classmates 358 Accept and Apply Newton as the Foundation of Movement Analysis 359 Talk Fluent Biomechanics with Your Classmates 359 Volunteer for Research Projects 360 Attend a Biomechanics Conference 361 Index 363

    3 in stock

    £16.19

  • Life on the Edge

    Transworld Publishers Ltd Life on the Edge

    10 in stock

    Book SynopsisAre we missing a vital ingredient in its creation? Like Richard Dawkins' The Selfish Gene, which provided a new perspective on evolution, Life on the Edge alters our understanding of life's dynamics as Jim Al-Khalili and Johnjoe Macfadden reveal the hitherto missing ingredient to be quantum mechanics.Trade ReviewHugely ambitious ... the skill of the writing provides the uplift to keep us aloft as we fly through the strange and spectacular terra incognita of genuinely new science. -- Tom Whipple * The Times *Physicist Jim Al-Khalili and molecular biologist Johnjoe McFadden explore this extraordinary realm with cogency and wit. * Nature Magazine *A really original science book about a new field of research ... Groundbreaking. -- Clive Cookson * Financial Times *This thrilling book is an overview of a field that barely exists ... Al-Khalili has a genius for illustrating complex ideas via imaginative sidetracks. * The Sunday Telegraph *'Life on the Edge’ gives the clearest account I’ve ever read of the possible ways in which the very small events of the quantum world can affect the world of middle-sized living creatures like us. With great vividness and clarity it shows how our world is tinged, even saturated, with the weirdness of the quantum. * Philip Pullman *

    10 in stock

    £10.44

  • So Simple a Beginning

    Princeton University Press So Simple a Beginning

    2 in stock

    Book Synopsis

    2 in stock

    £18.04

  • Theoretical Biology of the Cell

    Cambridge University Press Theoretical Biology of the Cell

    2 in stock

    Book Synopsis

    2 in stock

    £56.99

  • Every Life Is On Fire: How Thermodynamics

    Basic Books Every Life Is On Fire: How Thermodynamics

    1 in stock

    Book SynopsisWhy are we alive? Most things in the universe aren't. And if you trace the evolutionary history of plants and animals back far enough, you will find that, at some point, neither were we. Scientists have wrestled with this problem for centuries, and no one has been able to offer a credible theory. But in 2013, at just 30 years old, biophysicist Jeremy England published a paper that has utterly upended the ongoing study of life's origins. In Every Life Is on Fire, he describes, for the first time, his highly publicized theory known as dissipative adaptation. In any disordered system, matter clumps together and breaks apart, mostly randomly, without consequence. But some of the clumps that form are momentarily better at doing one specific job: dissipating energy. These structures are less likely to fall apart. Over time, they become better at both withstanding the disorder surrounding them and creating copies of themselves. From this deep insight, grounded in thermodynamics, England is able to isolate the emergence of the first life-like behaviors. Scientists have always thought that life began as a stroke of spectacular luck. But in fact, life may be inevitable, a product of the iron physical laws of the universe.England is both a world-class physicist and an ordained rabbi, and so his enquiry doesn't end with the physics of life. We ask questions like "How did life begin?" not just for the fun of scientific inquiry, but because we want a deeper understanding of who we are and why we're here. Even if physics can explain how life-like behaviors emerged, England doubts that reducing life down to the energy flows of a bunch of microscopic particles can ever give us a satisfying answer to what it means to be alive?. He believes that life is fundamentally a philosophical distinction, not a natural one. So before we can seriously look for life's physical origins, we must first make basic choices about what we think life means. This is something researchers often fail to recognize, and it is why, throughout In Every Life Is on Fire, England informs the premises of his theory with a careful exploration of what life is for.For anyone who reads this book, no matter their creed, In Every Life Is On Fire offers a rare work of popular science that explores not just what science does, but how it imbues our lives with meaning.

    1 in stock

    £20.69

  • Biophysics

    Princeton University Press Biophysics

    20 in stock

    Book SynopsisOffers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. This title emphasizes the unifying power of abstract physical principles to motivate advanced experiments on biological systems. It covers a range of biological phenomena from the physicist's perspective.Trade ReviewWilliam Bialek, Winner of the 2013 Swartz Prize for Theoretical and Computational Neuroscience, Society for Neuroscience "[T]he book goes beyond being a structured material for readers to learn about biophysics; it takes readers on an incredible journey in discovering fascinating ways in which biological phenomena can be viewed and studied. The technical adroitness and more importantly, the unique way of thinking about biological problems, in the reviewer's opinion, makes the book a must-read for any aspiring biophysicists."--Angie Ma, Contemporary Physics "[P]hysicists who are seeking an exciting intellectual path through the complexity of biology will deeply appreciate Bialek's clear vision of the big ideas and his expert guidance through their many applications."--Stephen J. Hagen, Physics Today "The book is well crafted, linking the historic work of the 'giants', e.g. Helmholtz with his seminal view of vision and hearing, with latest and trendy research, exemplified by the use of information theory in biology."--Robert Endres, Biological Physics Group NewsletterTable of ContentsAcknowledgments ix PART I EXPLORING THE PHENOMENA 1. Introduction 3 *1.1 About Our Subject 3 *1.2 About This Book 11 2. Photon Counting in Vision 17 *2.1 A First Look 17 *2.2 Dynamics of Single Molecules 51 *2.3 Biochemical Amplification 68 *2.4 The First Synapse and Beyond 97 *2.5 Coda 115 3. Lessons, Problems, Principles 117 PART II CANDIDATE PRINCIPLES 4. Noise Is Not Negligible 127 *4.1 Fluctuations and Chemical Reactions 127 *4.2 Motility and Chemotaxis in Bacteria 149 *4.3 Molecule Counting, More Generally 172 *4.4 More about Noise in Perception 192 *4.5 Proofreading and Active Noise Reduction 218 *4.6 Perspectives 245 5. No Fine Tuning 247 *5.1 Sequence Ensembles 248 *5.2 Ion Channels and Neuronal Dynamics 279 *5.3 The States of Cells 299 *5.4 Long Time Scales in Neural Networks 329 *5.5 Perspectives 349 6. Efficient Representation 353 *6.1 Entropy and Information 354 *6.2 Noise and Information Flow 369 *6.3 Does Biology Care about Bits? 395 *6.4 Optimizing Information Flow 421 *6.5 Gathering Information and Making Models 449 *6.6 Perspectives 467 7. Outlook 469 Appendix Some Further Topics 473 * A.1 Poisson Processes 473 * A.2 Correlations, Power Spectra, and All That 484 * A.3 Diffraction and Biomolecular Structure 495 * A.4 Electronic Transitions in Large Molecules 503 * A.5 The Kramers Problem 512 * A.6 Berg and Purcell, Revisited 521 * A.7 Maximum Entropy 533 * A.8 Measuring Information Transmission 545 Annotated Bibliography 557 Index 625

    20 in stock

    £80.75

  • Taxonomic Impediments of the Benthic Infauna Potential Solutions and Consequences

    1 in stock

    £132.05

  • Huang H Introduction to Cell Mechanics and

    CRC Press Huang H Introduction to Cell Mechanics and

    1 in stock

    Book SynopsisIntroduction to Cell Mechanics and Mechanobiology is designed for a one-semester course in the mechanics of the cell offered to advanced undergraduate and graduate students in biomedical engineering, bioengineering, and mechanical engineering. It teaches a quantitative understanding of the way cells detect, modify, and respond to the physical properties within the cell environment. Coverage includes the mechanics of single molecules, polymers, polymer networks, two-dimensional membranes, whole-cell mechanics, and mechanobiology, as well as primer chapters on solid, fluid, and statistical mechanics, and cell biology.Introduction to Cell Mechanics and Mechanobiology is the first cell mechanics textbook to be geared specifically toward students with diverse backgrounds in engineering and biology.Trade Review"The new text from Jacobs, Huang, and Kwon is fully worthy of the honor of being the first text reviewed in Cellular and Molecular Bioengineering. After reading through the clear, simple, but rigorous text, I can say that their work does far more than just tie together some important notes in a single binding....this text is potentially transformative for the field, much in the way that the famous texts by Beer and Johnston, in the 1960s were transformative for the undergraduate study of mechanics of materials and machines." - Cellular and Molecular Bioengineering "This excellent book by a group of internationally recognized authors meets a real existing need in contemporary bioengineering education, and it does it effectively and successfully....The book was exactly what I wanted; it was entirely devoted to cell-scale problems, with numerous examples, each providing the relevant engineering or mathematical formulation, at a level suitable for good undergrad BME students....All chapters are comprehensible, logically-built and concise, and each is supported by high-quality graphics which add very much to the clarity of the contents...this book is a 'must-have'." - Computer Methods in Biomechanics and Biomedical Engineering“…[Introduction to Cell Mechanics and Mechanobiology] touches on all the main current techniques used to apply force to cells and to measure the forces exerted by cells….the physics behind them is well explained and derived…The book sets up a good context for why one would want to study mechanobiology and gives some good tips for designing an experiment, taking into account the fundamental differences in biology and engineering practices.”- Yale Journal of Biology and MedicineTable of ContentsPart I. Principles1. Cell Mechanics as a Framework2. Fundamentals of Cell Biology3. Solid Mechanics Primer4. Fluid Mechanics Primer5. Statistical Mechanics PrimerPart II. Practices6. Cell Mechanics in the Laboratory 7. Mechanics of Cellular Polymers8. Polymer Networks and the Cytoskeleton9. Mechanics of the Cell Membrane10. Adhesion, Migration, and Contraction of the Cell11. Mechanotransduction and Intracellular Signaling

    1 in stock

    £68.39

  • Physical Biology of the Cell

    Taylor & Francis Inc Physical Biology of the Cell

    1 in stock

    Book SynopsisPhysical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that unite a given set of biological phenomena. Herein lies the central premise: that the appropriate application of a few fundamental physical models can serve as the foundation of whole bodies of quantitative biological intuition, useful across a wide range of biological problems. The Second Edition features full-color illustrations throughout, two new chapters, a significantly expanded set of end-of-chapter problems, and is available in a variety of e-book formats.Trade Review“The book is well illustrated, problems and references complete each chapter, figures and other data can be downloaded from the Garland Science Web site. Its public is assumed to be students taking a first course in physical biology or biophysics, and scientists interested in physical modelling in biology. Physical Biology of the Cell has much to offer to both categories…”- Crystallography Reviews“This textbook is an excellent resource, both for a research scientist and for a teacher. The authors do a superb job of selecting the material for each chapter and explaining the material with equations and narrative in an easily digestible manner.”—Yale Journal of Biology and Medicine (YJBM)Praise for the First Edition of Physical Biology of the Cell“Physical Biology of the Cell…aims to be both an introduction to molecular and cellular biology for physicists and an introduction to physics for biologists. Though that sounds like a daunting task, the book fully and impressively delivers. Physical Biology of the Cell might well become a similar classic [as Molecular Biology of the Cell] for anyone who heeds its mantra “quantitative data demand quantitative models.” It will give both physicists and biologists a useful introduction into the other camp’s methods and ways of thinking.”—Ralf Bundschuh, Physics Today, 2009“[The] authors of Physical Biology of the Cell have produced one of the first multi-purpose textbooks that is readily accessible to both physicists and biologists….When read from cover to cover, the book is both very instructive and highly entertaining, with the authors using humor to deliver strong take-home messages in each chapter....Physical Biology of the Cell provides instructors with excellent material to create a graduate level course in biology or physics.”—Patricia Bassereau and Pierre Nasoy, Nature Cell Biology, 2009“Physical Biology of the Cell is beautifully crafted: self-contained and modular, it provides tutorials on fundamentals and has material to hold the interest of a more sophisticated reader. It is fast-paced, proceeding within each chapter from freshman basics to graduate level sophistication. To truly master the physics presented in thebook, one should do the problems provided with each chapter. These problems are well thought out and are a major teaching resource.”—Boris Shraiman, Cell, 2009“…a monumental undertaking by three outstanding experts in the field…the book is a rich collection of special topics in biophysics…”—Gabor Forgacs, Quarterly Review of Biology, 2009“I would thoroughly recommend [Physical Biology of the Cell] to anyone interested in investigating or applying biophysical research methods to their work. It is likely to be a fantastic teaching tool and is a welcome addition in this age of increasinglyinterdisciplinary science.”—David Stephens, The British Society for Cell Biology Newsletter, 2009“The book is well illustrated, problems and references complete each chapter, figures and other data can be downloaded from the Garland Science Web site. Its public is assumed to be students taking a first course in physical biology or biophysics, and scientists interested in physical modelling in biology. Physical Biology of the Cell has much to offer to both categories…”- Crystallography Reviews“This textbook is an excellent resource, both for a research scientist and for a teacher. The authors do a superb job of selecting the material for each chapter and explaining the material with equations and narrative in an easily digestible manner.”—Yale Journal of Biology and Medicine (YJBM)Praise for the First Edition of Physical Biology of the Cell: “Physical Biology of the Cell…aims to be both an introduction to molecular and cellular biology for physicists and an introduction to physics for biologists. Though that sounds like a daunting task, the book fully and impressively delivers. Physical Biology of the Cell might well become a similar classic [as Molecular Biology of the Cell] for anyone who heeds its mantra “quantitative data demand quantitative models.” It will give both physicists and biologists a useful introduction into the other camp’s methods and ways of thinking.”—Ralf Bundschuh, Physics Today, 2009“[The] authors of Physical Biology of the Cell have produced one of the first multi-purpose textbooks that is readily accessible to both physicists and biologists….When read from cover to cover, the book is both very instructive and highly entertaining, with the authors using humor to deliver strong take-home messages in each chapter....Physical Biology of the Cell provides instructors with excellent material to create a graduate level course in biology or physics.”—Patricia Bassereau and Pierre Nasoy, Nature Cell Biology, 2009“Physical Biology of the Cell is beautifully crafted: self-contained and modular, it provides tutorials on fundamentals and has material to hold the interest of a more sophisticated reader. It is fast-paced, proceeding within each chapter from freshman basics to graduate level sophistication. To truly master the physics presented in thebook, one should do the problems provided with each chapter. These problems are well thought out and are a major teaching resource.”—Boris Shraiman, Cell, 2009“…a monumental undertaking by three outstanding experts in the field…the book is a rich collection of special topics in biophysics…”—Gabor Forgacs, Quarterly Review of Biology, 2009“I would thoroughly recommend [Physical Biology of the Cell] to anyone interested in investigating or applying biophysical research methods to their work. It is likely to be a fantastic teaching tool and is a welcome addition in this age of increasinglyinterdisciplinary science.”—David Stephens, The British Society for Cell Biology Newsletter, 2009Table of ContentsPart I: The Facts of Life1. Why: Biology by the Numbers 2. What and Where 3. When: Stopwatches at Many Scales 4. Who: "Bless the Little Beasties"Part II: Life at Rest5. Mechanical and Chemical Equilibrium 6. Entropy Rules! 7. Two-State Systems 8. Random Walks and the Structure of Macromolecules 9. Electrostatics for Salty Solutions 10. Beam Theory 11. Biological MembranesPart III: Life in Motion12. The Mathematics of Water 13. A Statistical View of Biological Dynamics14. Crowded and Disordered Environments 15. Rate Equations and Dynamics in the Cell 16. Dynamics of Molecular Motors 17. Biological Electricity 18. Light and Life – NEW CHAPTERPart IV: The Meaning of Life19. Organization of Biological Networks20. Biological Patterns: Order in Space and Time – NEW CHAPTER21. Sequences, Specificity, and Evolution 22. Whither Physical Biology?

    1 in stock

    £87.39

  • Introduction to Biological Physics for the Health

    John Wiley & Sons Inc Introduction to Biological Physics for the Health

    1 in stock

    Book SynopsisA thoroughly updated and extended new edition of this well-regarded introduction to the basic concepts of biological physics for students in the health and life sciences. Designed to provide a solid foundation in physics for students following health science courses, the text is divided into six sections: Mechanics, Solids and Fluids, Thermodynamics, Electricity and DC Circuits, Optics, and Radiation and Health. Filled with illustrative examples, Introduction to Biological Physics for the Health and Life Sciences, Second Edition features a wealth of concepts, diagrams, ideas and challenges, carefully selected to reference the biomedical sciences. Resources within the text include interspersed problems, objectives to guide learning, and descriptions of key concepts and equations, as well as further practice problems. NEW CHAPTERS INCLUDE: Optical Instruments Advanced Geometric Optics Thermodynamic Processes HeTable of ContentsI Mechanics 1 Chapter 1 Kinematics 3 Chapter 2 Force and Newton’s Laws of Motion 17 Chapter 3 Motion in a Circle 31 Chapter 4 Statics 37 Chapter 5 Energy 47 Chapter 6 Momentum 61 Chapter 7 Simple Harmonic Motion 69 Chapter 8 Waves 79 Chapter 9 Sound and Hearing 91 II Solids and Fluids 107 Chapter 10 Elasticity: Stress and Strain 109 Chapter 11 Pressure 119 Chapter 12 Buoyancy 133 Chapter 13 Surface Tension and Capillarity 141 Chapter 14 Fluid Dynamics of Non-viscous Fluids 149 Chapter 15 Fluid Dynamics of Viscous Fluids 159 Chapter 16 Molecular Transport Phenomena 165 III Thermodynamics 171 Chapter 17 Temperature and the Zeroth Law 173 Chapter 18 Ideal Gases 185 Chapter 19 Phase and Temperature Change 199 Chapter 20 Water Vapour and the Atmosphere 213 Chapter 21 Heat Transfer 227 Chapter 22 Thermodynamics and the Body 239 Chapter 23 Thermodynamic Processes in Ideal Gases 249 Chapter 24 Heat Engines and Entropy 263 Chapter 25 Energy Availability and Thermodynamic Potentials 279 IV Electricity and DC Circuits 293 Chapter 26 Static Electricity 295 Chapter 27 Electric Force and Electric Field 301 Chapter 28 Electrical Potential and Energy 311 Chapter 29 Capacitance 323 Chapter 30 Direct Currents and DC Circuits 333 Chapter 31 Time Behaviour of RC Circuits 351 V Optics 359 Chapter 32 The Nature of Light 361 Chapter 33 Geometric Optics 375 Chapter 34 The Eye and Vision 393 Chapter 35 Wave Optics 411 Chapter 36 Advanced Geometric Optics 429 Chapter 37 Optical Instruments 449 Chapter 38 Atoms and Atomic Physics 463 Chapter 39 The Nucleus and Nuclear Physics 475 Chapter 40 Production of Ionising Radiation 485 Chapter 41 Interactions of Ionising Radiation 499 Chapter 42 Biological Effects of Ionising Radiation 509 Chapter 43 Medical Imaging 519 Chapter 44 Magnetism and MRI 525 Appendices 550 Appendix A Physical Constants 551 Appendix B Basic Maths and Science Skills 553 Appendix C Answers to Odd Numbered Problems 565 Selected Further Reading 576 Index 579

    1 in stock

    £56.00

  • Becoming Earth

    Pan Macmillan Becoming Earth

    4 in stock

    Book SynopsisA revolutionary and hopeful account of Earth not simply as an inanimate planet on which life evolved but as a planet which came to life.

    4 in stock

    £11.69

  • Everything Moves: How Biotensegrity Informs Human

    Jessica Kingsley Publishers Everything Moves: How Biotensegrity Informs Human

    5 in stock

    Book Synopsis''What a multi-sensory pleasure in learning! I will be a better teacher and better clinician using what I am learning from this book.'' Carol M Davis DPT, EdD, MS, FAPTAThe emerging science of biotensegrity provides a fresh context for re-thinking our understanding of human movement, but its complexities can be formidable. Bodywork and movement professionals looking for an accessible and relevant guide to the concept and application of biotensegrity need look no further than Everything Moves: How biotensegrity informs human movement.In order to work with our own bodies and the bodies of our students, clients and teams most effectively, we need to understand the nature of our human structure. Everything Moves offers the enquiring bodyworker or movement professional, who wants to take their understanding of how to apply biotensegrity in their work to the next level, a practical and relatable guide to the biotensegral nature of our bodies, in which all of the parts are one, yet all are constantly changing.Throughout Everything Moves, concepts and ideas are presented with activities and exercises to make them tangible, accessible and applicable. The material presented is suitable for coaches and movement teachers new to biotensegrity, as well as those with more advanced levels of understanding.Whether your focus is performance, sports, Alexander Technique, Feldenkrais, yoga, Pilates, martial arts, or dance, any arena in which bodies move can be informed by Everything Moves!

    5 in stock

    £39.90

  • Springer How Birds Find Their Way

    1 in stock

    Book SynopsisPreface.- 1 Prelude The Return of AX658.- 2 True Navigation.- 3 Unconventional Signs.- 4 The Flight of the Dove.- 5 Avian Magnetoreception.- 6 Migration.- 7 Life on the Wing.- 8 The Geography of the Species.- 9 Epilogue.

    1 in stock

    £21.84

  • Physics of the Human Body

    Springer International Publishing AG Physics of the Human Body

    1 in stock

    Book SynopsisThis book comprehensively addresses the physics and engineering aspects of human physiology by using and building on first-year college physics and mathematics. Topics include the mechanics of the static body and the body in motion, the mechanical properties of the body, muscles in the body, the energetics of body metabolism, fluid flow in the cardiovascular and respiratory systems, the acoustics of sound waves in speaking and hearing, vision and the optics of the eye, the electrical properties of the body, and the basic engineering principles of feedback and control in regulating all aspects of function. The goal of this text is to clearly explain the physics issues concerning the human body, in part by developing and then using simple and subsequently more refined models of the macrophysics of the human body. Many chapters include a brief review of the underlying physics. There are problems at the end of each chapter; solutions to selected problems are also provided. This second edition enhances the treatments of the physics of motion, sports, and diseases and disorders, and integrates discussions of these topics as they appear throughout the book. Also, it briefly addresses physical measurements of and in the body, and offers a broader selection of problems, which, as in the first edition, are geared to a range of student levels. This text is geared to undergraduates interested in physics, medical applications of physics, quantitative physiology, medicine, and biomedical engineering.Table of ContentsPreface.- Terminology, the Standard Human, and Scaling.- Statics of the Body.- Motion.- Mechanical Properties of the Body.- Muscles.- Metabolism: Energy, Heat, Work, and Power of the Body.- Fluid Pressure, Fluid Flow in the Body, and Motion in Fluids.- Cardiovascular System.- Lungs and Breathing.- Sound, Speech, and Hearing.- Light, Eyes, and Vision.- Electrical and Magnetic Properties.- Feedback and Control.

    1 in stock

    £89.99

  • Physics Of Cancer, The: Research Advances

    World Scientific Publishing Co Pte Ltd Physics Of Cancer, The: Research Advances

    1 in stock

    Book SynopsisCancer deaths per capita have decreased in recent years, but the improvement is attributed to prevention, not treatment. The difficulty in treating cancer may be due to its 'complexity', in the mathematical physics sense of the word. Tumors evolve and spread in response to internal and external factors that involve feedback mechanisms and nonlinear behavior. Investigations of the nonlinear interactions among cells, and between cells and their environment, are crucial for developing a sufficiently detailed understanding of the system's emergent phenomenology to be able to control the behavior. In the case of cancer, controlling the system's behavior will mean the ability to treat and cure the disease. Physicists have been studying various complex, nonlinear systems for many years using a variety of techniques. These investigations have provided insights that allow physicists to make unique contributions towards the treatment of cancer.This interdisciplinary book presents recent advancements in physicists' research on cancer. The work presented in this volume uses a variety of physical, biochemical, mathematical, theoretical, and computational techniques to gain a deeper molecular and cellular understanding of the horrific disease that is cancer.

    1 in stock

    £72.00

  • Handbook of Sample Preparation for Scanning Electron Microscopy and Xray Microanalysis

    Springer-Verlag New York Inc. Handbook of Sample Preparation for Scanning Electron Microscopy and Xray Microanalysis

    1 in stock

    Book SynopsisScanning electr on microscopy (SEM) and x-ray microanalysis can produce magnified images and in situ chemical information from virtually any type of specimen. The two instruments generally operate in a high vacuum and a very dry environment in order to produce the high energy beam of electrons needed for imaging and analysis. With a few notable exceptions, most specimens destined for study in the SEM are poor conductors and composed of beam sensitive light elements containing variable amounts of water. In the SEM, the imaging system depends on the specimen being sufficiently electrically conductive to ensure that the bulk of the incoming electrons go to ground. The formation of the image depends on collecting the different signals that are scattered as a consequence of the high energy beam interacting with the sample. Backscattered electrons and secondary electrons are generated Trade ReviewThis handbook should find its way to the reference bookshelf of all imaging laboratories. It should also become required reading for anyone being trained for SEM work, or anyone who might need to have their samples examined by using such techniques. In that way, it will be less likely that deficient results will be published and that the full potential of the SEM be realized. -- Iolo ap Gwynn, Microscopy and Microanalysis (2010)Table of ContentsSample Collection and Selection.- Sample Preparation Tools.- Sample Support.- Sample Embedding ?and Mounting.- Sample Exposure.- Sample Dehydration.- Sample Stabilization for Imaging in the SEM.- Sample Stabilization to Preserve Chemical Identity.- Sample Cleaning.- Sample Surface Charge Elimination.- Sample Artifacts and Damage.- Additional Sources of Information.

    1 in stock

    £113.99

  • Mathematical Biology

    Springer-Verlag New York Inc. Mathematical Biology

    1 in stock

    Book SynopsisProviding an in-depth look at the practical use of math modeling, it features exercises throughout that are drawn from a variety of bioscientific disciplines - population biology, developmental biology, physiology, epidemiology, and evolution, among others.Trade ReviewReviews of the original edition: "Murray has produced a magnificent compilation of mathematical models and their applications in biology." Nature "Murray's Mathematical Biology belongs on the shelf of any person with a serious interest in mathematical biology." Bulletin of Mathematical Biology SIAM, 2004: "Murray's Mathematical Biology is a classic that belongs on the shelf of any serious student or researcher in the field. Together the two volumes contain well over 1000 references, a rich source of material, together with an excellent index to help readers quickly find key words. ... I recommend the new and expanded third edition to any serious young student interested in mathematical biology who already has a solid basis in applied mathematics." From the reviews of the third edition: "Mathematical Biology would be eminently suitable as a text for a final year undergraduate or postgraduate course in mathematical biology … . It is also a good source of examples for courses in mathematical methods … . Mathematical Biology provides a good way in to the field and a useful reference for those of us already there. It may attract more mathematicians to work in biology by showing them that there is real work to be done." (Peter Saunders, The Mathematical Gazette, Vol. 90 (519), 2006)Table of ContentsContinuous Population Models for Single Species * Discrete Population Models for a Single Species * Models for Interacting Populations * Temperature-Dependent Sex Determination (TSD): Crocodilian Survivorship * Modelling the Dynamics of Marital Interaction: Divorce Prediction and Marriage Repair * Reaction Kinetics * Biological Oscillators and Switches * BZ Oscillating Reactions * Perturbed and Coupled Oscillators and Black Holes * Dynamics of Infectious Diseases: Epidemic Models and AIDS * Reaction Diffusion, Chemotaxis, and Non-local Mechanisms * Oscillator Generated Wave Phenomena and Central Pattern Generators * Biological Waves: Single Species Models * Use and Abuse of Fractals

    1 in stock

    £80.99

  • Mathematical Biology II

    Springer-Verlag New York Inc. Mathematical Biology II

    1 in stock

    Book SynopsisThis richly illustrated third edition provides a thorough training in practical mathematical biology and shows how exciting mathematical challenges can arise from a genuinely interdisciplinary involvement with the biosciences.Trade ReviewFrom the reviews: "The 2nd volume of the authors elucidating work highlights a surprisingly broad spectrum of applications in the field of mathematical biology. The sense given to the mathematical texture of thoughts broadens the reader’s insight … . The growing number of specialists in sub-disciplines of mathematical biology will be enjoying the truly concise approach … . It can so be said that the foremost results … might be essential for new interpretations of data … . It is a recommended text for mathematicians … ." (Daniel Gertsch, Bioworld, Issue 2, 2004) From the reviews of the third edition: "This is the second volume of the third edition of Murray’s ‘Mathematical Biology’. … covers a wide variety of problems in pattern formation, each discussed in its biological context. … This volume alone is a large book, with more than 800 pages and a similar number of references. … it is a valuable collection of results from different areas of mathematical biology." (Carlo Laing, New Zealand Mathematical Society Newsletter, Issue 90, April, 2004) "This book, a classical text in mathematical biology, cleverly combines mathematical tools with subject area sciences. The multi-layer way of material presentation makes the book useful for different types of reader including graduate-level students, bioscientists … . it is an enjoyable reading and I recommend it to anyone with serious interest in mathematical modelling." (V.V. Fedorov, Short Book Reviews, Vol. 23 (3), 2003) "This second volume of the third edition of Murray’s Mathematical biology focuses on partial differential equations (spatial models) and their application to the biomedical sciences. … Each chapter deals with its particular topic in great detail, usually focusing on one biological example and the associated mathematical model and results. This volume is not an introductory text … making it extremely useful in graduate courses and for reference." (Trachette L. Jackson, Mathematical Reviews, 2004b) "In this second volume … the development towards specific biological configurations and towards a mechanism for understanding morphogenesis represents an important portion of the work. … chapters deal with attractive topics … . There is an extensive index at the end. … very interesting and strongly recommended." (A. Akutowicz, Zentralblatt MATH, Vol. 1006, 2003) "In this volume it becomes clear that compiling the third edition was a ‘labor of love’. The book has a significantly different feel from the original first edition. … my reaction to the third edition was positive. … The historical and biological overviews have much interesting information. … Certainly, the spicy writing will keep students alert … . In summary, I recommend the new and expanded third edition to any serious young student interested in mathematical biology … ." (Leah Edelstein-Keshet, SIAM Review, Vol. 46 (1), 2004) "Mathematical Biology would be eminently suitable as a text for a final year undergraduate or postgraduate course in mathematical biology … . It is also a good source of examples for courses in mathematical methods … . Mathematical Biology provides a good way into the field and a useful reference for those of us already there. It may attract more mathematicians to work in biology by showing them that there is real work to be done." (Peter Saunders, The Mathematical Gazette, Vol. 90 (518), 2006)Table of ContentsMulti-Species Waves and Practical Applications * Spatial Pattern Formation with Reaction Diffusion Systems * Animal Coat Patterns and Other Practical Applications of Reaction Diffusion Mechanisms * Pattern Formation on Growing Domains: Alligators and Snakes * Bacterial Patterns and Chemotaxis * Mechanical Theory for Generating Pattern and Form in Development * Evolution, Morphogenetic Laws, Developmental Constraints and Teratologies * A Mechanical Theory of Vascular Network Formation * Epidermal Wound Healing * Dermal Wound Healing * Growth and Control of Brain Tumours * Neural Models of Pattern Formation * Geographic Spread and Control of Epidemics * Wolf Territoriality, Wolf-Deer Interaction and Survival

    1 in stock

    £113.99

  • Isothermal Titration Calorimetry in Enzymology

    1 in stock

    £131.25

  • Enzymatic Production of Oligosaccharides

    Elsevier Science Enzymatic Production of Oligosaccharides

    1 in stock

    1 in stock

    £140.00

  • Fungal and Protozoan Carbonic Anhydrases

    Elsevier Science Fungal and Protozoan Carbonic Anhydrases

    1 in stock

    1 in stock

    £104.50

  • Protein Aggregation  Part B

    Elsevier Science Protein Aggregation Part B

    1 in stock

    1 in stock

    £113.05

  • The Fluid Dynamics of Cell Motility

    Cambridge University Press The Fluid Dynamics of Cell Motility

    1 in stock

    Book SynopsisFluid dynamics plays a crucial role in many cellular processes, including the locomotion of cells such as bacteria and spermatozoa. These organisms possess flagella, slender organelles whose time periodic motion in a fluid environment gives rise to motility. Sitting at the intersection of applied mathematics, physics and biology, the fluid dynamics of cell motility is one of the most successful applications of mathematical tools to the understanding of the biological world. Based on courses taught over several years, it details the mathematical modelling necessary to understand cell motility in fluids, covering phenomena ranging from single-cell motion to instabilities in cell populations. Each chapter introduces mathematical models to rationalise experiments, uses physical intuition to interpret mathematical results, highlights the history of the field and discusses notable current research questions. All mathematical derivations are included for students new to the field, and end-of-Table of ContentsPart I. Fundamentals: 1. Biological background; 2. The fluid dynamics of microscopic locomotion; 3. The waving sheet model; 4. The squirmer model; Part II. Cellular locomotion: 5. Flagella and the physics of viscous propulsion; 6. Hydrodynamics of slender filaments; 7. Waving of eukaryotic flagella; 8. Rotation of bacterial flagellar filaments; 9. Flows and stresses induced by cells; Part III. Interactions: 10. Swimming cells in flows; 11. Self-propulsion and surfaces; 12. Hydrodynamic synchronisation; 13. Diffusion and noisy swimming; 14. Hydrodynamics of collective locomotion; 15. Locomotion and transport in complex fluids; References; Index.

    1 in stock

    £41.79

  • A Practical Guide to Quasi-elastic Neutron

    Royal Society of Chemistry A Practical Guide to Quasi-elastic Neutron

    1 in stock

    Book SynopsisThe technique of Quasi-Elastic Neutron Scattering (QENS) is a powerful experimental tool for extracting temporal and spatial information at the nanoscale from both soft and hard condensed matter systems. However, while seemingly simple, the method is beset with sensitivities that, if ill considered, can hinder data interpretation and possibly publication. By highlighting key theoretical and data evaluation aspects of the technique, this specialised ‘primer style’ training resource encourages research success by guiding new researchers through a typical QENS experiment; from planning and sample preparation considerations to data reduction and subsequent analysis. Research examples are referenced throughout to illustrate the concepts addressed, with the book being written in such a way that it remains accessible to chemists, biologists, physicists, and materials scientists.Table of ContentsIf You Read Nothing Else...; What is QUENS?; Which Spectrometer Should I Choose?; Facility Access; The Measurement; Data Reduction; Elastic and Inelastic Fixed Window Scans; S(Q,ω) and I(Q,t); And Finally

    1 in stock

    £42.75

  • Fundamentals of Biomechanics

    Springer Nature Switzerland AG Fundamentals of Biomechanics

    1 in stock

    Book SynopsisBlending up-to-date biomechanical knowledge with professional application knowledge, this second edition presents a clear, conceptual approach to understanding biomechanics within the context of the qualitative analysis of human movement. It develops nine principles of biomechanics, which provide an applied structure for biomechanical concepts, and the application of each principle is fully explored in several chapters. The book also offers real-world examples of the application of biomechanics, which emphasize how biomechanics is integrated with the other subdisciplines of kinesiology to contribute to qualitative analysis of human movement.Table of ContentsPart I: Introduction1. Introduction to Biomechanics of Human Movement2. Fundamentals of Biomechanics and Qualitative AnalysisPart II: Biological/Structural Bases3. Anatomical Description and Its Limitations4. Mechanics of the Musculoskeletal SystemPart III: Mechanical Bases5. Linear and Angular Kinematics6. Linear Kinetics7. Angular Kinetics8. Fluid MechanicsPart IV: Applications of Biomechanics in Qualitative Analysis9. Applying Biomechanics in Physical Education10. Applying Biomechanics in Coaching11. Applying Biomechanics in Strength and Conditioning12. Applying Biomechanics in Sports Medicine and RehabilitationAppendicesIndex

    1 in stock

    £67.49

  • Electromechanobiology of Cartilage and Osteoarthritis: A Tribute to Alan Grodzinsky on his 75th Birthday

    Springer International Publishing AG Electromechanobiology of Cartilage and Osteoarthritis: A Tribute to Alan Grodzinsky on his 75th Birthday

    1 in stock

    Book SynopsisThis is an open access book. In honor of his 75th birthday, we reflect on the impact of the pioneering work of Alan Grodzinsky and his laboratory. This volume includes in-depth discussions of tissue electromechanics, mechanobiology and biomechanics, and matrix biology in addition to the latest advancements in understanding the pathogenesis, progression and treatment of osteoarthritis. Unique to this volume, we overview decades of groundbreaking research that set the stage for the latest efforts in the field, highlighting the legacy of one researcher and their trainees.Table of ContentsPreface (Brianne K. Connizzo, Lin Han, Robert L. Sah).- Scientific Impact.- Chapter 1. Aggrecan and Hyaluronan: The infamous Cartilage Polyelectrolytes- Then and Now (Anna Plaas, Meghan Moran, John Sandy, Vincent Hascall).- Chapter 2. Understanding the Influence of Local Physical Stimuli on Chondrocyte Behavior (Byumsu Ki, Lawrence J. Bonassar).- Chapter 3. Multiscale In Silico Modeling of Cartilage Injuries (Rami K. Korhonen, Atte S.A. Eskelinen, Gustavo A. Orozco, Amir Esrafilian, Cristina Florea, and Petri Tanska).- Chapter 4. In Vitro Models and Proteomics in Osteoarthritis Research (Martin Rydén, Patrik Önnerfjord).- Chapter 5. Nanomechanics of Aggrecan: A New Perspective on Cartilage Biomechanics, Disease and Regeneration (Chao Wang, Elizabeth R. Kahle, Lin Han).- Chapter 6. Computational Modelling for Managing Pathways to Cartilage Failure (Saeed Miramini, David W. Smith, Bruce S. Gardiner, Lihai Zhang).- Chapter 7. Gene Delivery to Chondrocytes (Christopher V. Nagelli, Christopher H. Evans, Rodolfo E. De la Vega).- Chapter 8. Mechanical Articular Cartilage Injury Models and Their Relevance in Advancing Therapeutic Strategies (Bodo Kurz, Melanie L Hart, Bernd Rolauffs).- Chapter 9. Hip Osteoarthritis: Bench to Bedside Perspective (Young-Jo Kim).- Chapter 10. Harnessing Growth Factor Interactions to Optimize Articular Cartilage Repair (Stephen B. Trippel).- Personal Tributes.- Index.

    1 in stock

    £38.84

  • Modern Biophysical Chemistry: Detection and

    Wiley-VCH Verlag GmbH Modern Biophysical Chemistry: Detection and

    2 in stock

    Book SynopsisThis updated and up-to-date version of the first edition continues with the really interesting stuff to spice up a standard biophysics and biophysical chemistry course. All relevant methods used in current cutting edge research including such recent developments as super-resolution microscopy and next-generation DNA sequencing techniques, as well as industrial applications, are explained. The text has been developed from a graduate course taught by the author for several years, and by presenting a mix of basic theory and real-life examples, he closes the gap between theory and experiment. The first part, on basic biophysical chemistry, surveys fundamental and spectroscopic techniques as well as biomolecular properties that represent the modern standard and are also the basis for the more sophisticated technologies discussed later in the book. The second part covers the latest bioanalytical techniques such as the mentioned super-resolution and next generation sequencing methods, confocal fluorescence microscopy, light sheet microscopy, two-photon microscopy and ultrafast spectroscopy, single molecule optical, electrical and force measurements, fluorescence correlation spectroscopy, optical tweezers, quantum dots and DNA origami techniques. Both the text and illustrations have been prepared in a clear and accessible style, with extended and updated exercises (and their solutions) accompanying each chapter. Readers with a basic understanding of biochemistry and/or biophysics will quickly gain an overview of cutting edge technology for the biophysical analysis of proteins, nucleic acids and other biomolecules and their interactions. Equally, any student contemplating a career in the chemical, pharmaceutical or bio-industry will greatly benefit from the technological knowledge presented. Questions of differing complexity testing the reader's understanding can be found at the end of each chapter with clearly described solutions available on the Wiley-VCH textbook homepage under: www.wiley-vch.de/textbooksTable of ContentsIntroduction: What is Biophysical Chemistry? - An Example from Drug Screening PART I: Basic Methods in Biophysical Chemistry BASIC OPTICAL PRINCIPLES Introduction What Does the Electronic Structure of Molecules Look Like? Orbitals, Wave Functions and Bonding Interactions How Does Light Interact with Molecules? Transition Densities and the Transition Dipole Moment Absorption Spectra of Molecules in Liquid Environments. Vibrational Excitation and the Franck-Condon Principle What Happens After Molecules have Absorbed Light? Fluorescence, Nonradiative Transitions and the Triplet State Quantitative Description of all Processes: Quantum Efficiencies, Kinetics of Excited State Populations and the Jablonski Diagram Problems OPTICAL PROPERTIES OF BIOMOLECULES Introduction Experimental Determination of Absorption and Fluorescence Spectra Optical Properties of Proteins and DNA Optical Properties of Important Cofactors BASIC FLUORESCENCE TECHNQUES Introduction Fluorescent Labelling and Linking Techniques Fluorescence Detection Techniques Fluorscence Polarization Anisotropy Forster Resonance Energy Transfer Fluorescence Kinetics Fluorescence Recovery after Photobleaching Biochemiluminescence CHIROPTICAL AND SCATTERING METHODS Chiroptical Methods Light Scattering Vibrational Spectra of Biomolecules MAGNETIC RESONANCE TECHNIQUES Nuclear Magnetic Resonance of Biomolecules Electron Paramagnetic Resonance MASS SPECTROMETRY Introduction MALDI-TOF ESI-MS Structural and Sequence Analysis Using Mass Spectrometry PART II: Advanced Methods in Biophysical Chemistry FLUORESCENCE MICROSCOPY Introduction Conventional Fluorescence Microscopy Total Internal Reflection Fluorescence Microscopy Light-Sheet Microscopy SUPER-RESOLUTION FLUORESCENCE MICROSCOPY Stimulated Emission Depletion (STED) Microscopy Photoactivated Localization Microscopy (PALM) and Stochastic Optical Reconstruction Microscopy (STORM) 3D Super-Resolution Fluorescence Microscopy Imaging of Live Cells Multicolour Super-Resolution Fluorescence Microscopy Structured Illumination Microscopy SOFI Final Comparison SINGLE-BIOMOLECULE TECHNIQUES Introduction Optical Single-Molecule Detection Fluorescence Correlation Spectroscopy Optical Tweezers Atomic Force Microscopy of Biomolecules Patch Clamping ULTRAFAST- AND NONLINEAR SPECTROSCOPY Introduction Nonlinear Microscopy and Spectroscopy Ultrafast Spectroscopy DNA SEQUENCING AND NEXT-GENERATION SEQUENCING METHODS Sanger Method Next-Generation Sequencing Methods SPECIAL TECHNIQUES Introduction Fluorescing Nanoparticles Surface Plasmon Resonance Detection DNA Origami DNA Microarrays Flow Cytometry Fluorescence In Situ Hybridization Microspheres and Nanospheres ASSAY DEVELOPMENT, READERS AND HIGH-THROUGHPUT SCREENING Introduction Assay Development and Assay Quality Microtitre Plates and Fluorescence Readers Application Example: Drug Discovery and High-Throughput Screening Index

    2 in stock

    £51.00

  • Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Sensing with Ion Channels

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £123.49

  • Veins: Their Functional Role in the Circulation

    Springer Verlag, Japan Veins: Their Functional Role in the Circulation

    1 in stock

    Book SynopsisThe 8th International Congress of Biorheology was held at the Pacifico Yokohama, Japan, a brand new, versatile convention center for international meetings, from August 3 through 8, 1992. There were many plenary lectures and symposia, one of which was entitled "Mechanics of the Venous System." It was at this symposium that we, the editors of this monograph, each presented papers. We then moved to Gifu, Japan, for the Gifu Workshop on Veins and Vascular Capacitance. This was held on August 9, 1992, with the Second Department of Medicine, Gifu University School of Medicine, serving as the host. Nine papers were presented in the oral sessions and there were five poster presentations. This monograph, which is intended to provide a bird's­ eye view of recent trends in studies of the venous system, is an outgrowth of the Gifu Workshop. While it is not exactly the Proceedings ofthat workshop, materials in the monograph were developed from ideas presented there.

    1 in stock

    £40.49

  • Springer Nano-Optics for Enhancing Light-Matter Interactions on a Molecular Scale: Plasmonics, Photonic Materials and Sub-Wavelength Resolution

    15 in stock

    Book SynopsisThis volume presents a considerable number of interrelated contributions dealing with the new scientific ability to shape and control matter and electromagnetic fields on a sub-wavelength scale.The topics range from the fundamental ones, such as photonic metamateriials, plasmonics and sub-wavelength resolution to the more applicative, such as detection of single molecules, tomography on a micro-chip, fluorescence spectroscopy of biological systems, coherent control of biomolecules, biosensing of single proteins, terahertz spectroscopy of nanoparticles, rare earth ion-doped nanoparticles, random lasing, and nanocoax array architecture.The various subjects bridge over the disciplines of physics, biology and chemistry, making this volume of interest to people working in these fields. The emphasis is on the principles behind each technique and on examining the full potential of each technique.The contributions that appear in this volume were presented at a NATO Advanced Study Institute that was held in Erice, Italy, 3-18 July, 2011. The pedagogical aspect of the Institute is reflected in the topics presented in this volume.Table of ContentsPreface.- List of Past Institutes.- Lectures.- Real-time Optical Detection of Single Nanoparticles and Viruses using Heterodyne Interferometry; A. Mitra, L. Novotny.- Photonics Metamaterials and Transformation Optics; M. Wegener.- Plasmonic Enhancement of Light Emission and Scattering in Nanostructures; S. V. Gaponenko.- Sub-Wavelength Optical Fluorescence Microscopy for Biological Applications; P. N. Hedde, G. U. Nienhaus.- Raman Spectroscopy and Optical Coherence Tomography on a Micro-Chip; M. Pollnau et al.- Introduction to Fluorescence Spectroscopy with Applications in Biological Systems; B. Di Bartolo.- NanoPhotonics; C. Evans, E. Mazur.- Synthesis and Spectroscopy of Nanoparticles; A. P. Voitovich et al.- Photonic-Crystal Fiber Platform for Ultrafast Optical Science; A. Zheltikov.-Structure Property Relationships for Exciton Transfer in Conjugated Polymers; T. L. Andrews, T. M. Swager.- Coherent Control of Biomolecules and Imaging using Nanodoublers; L. Bonacina , J. P. Wolf.- Taking Whispering Gallery Mode Biosensing to the Single Protein Limit; S. Arnold et al.- Terahertz Spectroscopy and Imaging at the Nanoscale for Biological and Security Applications; J. W. Bowen.- Applications of Plasmonics in Biophotonics ; A. Heisterkamp et al.- Principles and Applications of Rare Earth Ion-Doped Nanoparticles ; J. M. Collins.- Is There Segregation in of Rare Earth Ions in Garnet Optical Ceramics; G. Boulon et al.- Random Lasing in Solid State Materials ; J. Fernandez et al.- Imprint-Templated Nanocoax Array Structure; M. J. Naughton.- Short Seminars.- Metallic Nanoclusters in Layered Crystals: Spectroscopy and Computer Simulations; I. Karbovnyk et al.- Optical Antennas for Single Emitter Fluorescence Enhancement; P. Bharadwaj, L. Novotny.- Ultrafast All-Optical Switching in TiO2; C. Evans et al.- Coherent Manipulation of Motional States of a Single Trapped Ion; A. S. Villar.-Thermalization of an Open Quantum System via Full Diagonalization; K. Jacobs, L. Silvestri.- The Role of Localized and Propagating Surface Plasmons in Periodically-Arrayed Nanopillars; F. J. Bezares et al.- Optical and Structural Properties of Noble Metal Island Films; M. Lončarić et al.- Localized Photonics States in Two-Dimensional Quasi-Crystalline Waveguides; G. Benedeck, A. Trabattoni.- Unified Theoretical Model of Loss Compensation and Energy Transfer for Plasmonic Nanoparticles Coated with a Shell of Active Gain Molecules; V. Pustovit et al.- Poster Presentations.- Deep UV Strategy for Discriminating Biomolecules; S. Afonina et al.- Silicon Nanowires Light Emitting Devices at Room Temperature; P. Artoni et al.- Optical and Structural Properties of Europium Oxide Thin Films on Si Substrates; G. Bellocchi et al.- Experimental Indication of Quantum Mechanical Effects in Surface Enhaced IR-Spectroscopy? ; J. Bochterle et al.- Spectral Dependence of the Amplification Factor in Surface Enhanced Raman Scattering ; C. D’Andrea et al.- Investigation of the Metal-Superconductor Hybrid Nanostructure as an Active Medium for Laser; A. Eid et al.- TiO2 for Nonlinear Optical Devices; C. Evans et al.- Atomic Layer Deposition of Lanthanide Oxides; P. A. Hansen et al.- Tip-Enhanced Raman Scattering from Bridged Metal Nanocones; M. J. Huttunen et al.- Femtosecond Laser Nanofabrication of Metal Structures through Multiphoton Photoreduction; S. Y. Kang et al.- Nanostructured Thick-Film Spinel Ceramic Materials for Sensor Device Applications; H. Klym, I. Karbovnyk.- Realization of a Two-Dimensional Isotropic Metamaterials; J. Kaschke et al.- Nanoscale Seminconductor Optical Devices; N. Kuznetsova et al.- Optical Properties of Thermochromic VO2 Nanoparticles; K. Laaksonen et al.- Lithium Niobate: The Silicon of Photonics!; M. Manzo et al.- Infrared Induced White Anti-Stokes Emissions LiYbP4O12 Nanocrystals; L. Marciniak et al.- Enhanced Light Emission from Si Nanocrystals Coupled to Plasmonic Structures; E. Massa et al.- A Spintronic Single Photon Source and Spin Manipulation in Spininjection-LEDs; A. Merz.- Polarizing Beam Splitters; J. Mueller, M. Wegener.- Point Defects Aggregation in LiF Crystals After Irradiation; A. P. Voitovich et al.- Diamond Photonic Crystal Slab with Enhanced Photoluminescence Extraction Efficiency; L. Ondič, I. Pelant.- Spectral Markers of Erythrocytes on Solid Substrate; A. A. Paiziev, V.A. Krakhmalev.- Lanthanide Doped Nanocrystalline Alkaline Earth Fluorides: Synthesis, Structural, Morphological and Spectroscopic Investigation; M. Pedroni et al.- Observation of Surface Plasmon in Metal-Coated Tapered Fiber Terminated by a Subwalength Aperture; V. Palm et al.- Fabrication of Single Photon Sources by Use of Pyramidal Quantum Dot Microcavities; D. Rülke et al.- Investigation of GaN- and CuInGaSe2- Based Heterostructures for Optoelectronics Applications; M. Z. Rzheutski et al.- Ebic Investigation of the Recombination at the Edges of GaAs Solar Cells; A. Scacabarozzi, M. Acciarri.- Dynamical Properties of Cardiomyocytes in Three-Dimensional Polymer Scaffolds; A. Scheiwe et al.- Femtosecond Laser Doped Silicon Photovoltaic Applications; M. J. Sher et al.- Laser and Optical Properties of Green-Emitting ZnCdSe Quantum Dot Based Heterostructures; A. G. Vainilovich et al.- Stokes Parameters Measurements for Whispering Gallery Modes Microcavities Characterization; F. Vanier et al.- Photonic Crystal Fiber Synthesizer for Ultrafast Lightwaves; A. A. Voronin et al.- Single Nanoparticle Surface Enhanced Fluorescence; L. R. Webster et al.- List of Participants.- Index.-

    15 in stock

    £170.99

  • Life on the Edge

    Random House USA Inc Life on the Edge

    10 in stock

    Book Synopsis

    10 in stock

    £17.00

  • Principles of Fluorescence Spectroscopy

    Springer Principles of Fluorescence Spectroscopy

    15 in stock

    Book Synopsisto Fluorescence.- Instrumentation for Fluorescence Spectroscopy.- Fluorophores.- Time-Domain Lifetime Measurements.- Frequency-Domain Lifetime Measurements.- Solvent and Environmental Effects.- Dynamics of Solvent and Spectral Relaxation.- Quenching of Fluorescence.- Mechanisms and Dynamics of Fluorescence Quenching.- Fluorescence Anisotropy.- Time-Dependent Anisotropy Decays.- Advanced Anisotropy Concepts.- Energy Transfer.- Time-Resolved Energy Transfer and Conformational Distributions of Biopolymers.- Energy Transfer to Multiple Acceptors in One,Two, or Three Dimensions.- Protein Fluorescence.- Time-Resolved Protein Fluorescence.- Multiphoton Excitation and Microscopy.- Fluorescence Sensing.- Novel Fluorophores.- DNA Technology.- Fluorescence-Lifetime Imaging Microscopy.- Single-Molecule Detection.- Fluorescence Correlation Spectroscopy.- Radiative Decay Engineering: Metal-Enhanced Fluorescence.- Radiative-Decay Engineering: Surface Plasmon-Coupled Emission.Trade ReviewPraise for Earlier Editions: "Lakowicz’s Principles of Fluorescence Spectroscopy has been the best one-volume introduction to the biophysical principles of fluorescence methods. - Roger Y. Tsien, Ph.D., Department of Pharmacology and Department of Chemistry and Biochemistry, University of California, San Diego, California "Principles of Fluorescence Spectroscopy is encyclopedic and comprehensive." - Britton Chance, Professor Emeritus in Biochemistry and Biophysics,University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania "Recommended without reservation both to the novice and to the expert in fluorescence." - Analytical Biochemistry "In addition to its use as a student text, it should be a particularly valuable reference for those involved in biochemical research." - Chemistry in Britain Advance Praise for Third Edition: "This third edition has significantly expanded the topics, and will remain as a leading reference, as well as a text…the information in the book is valuable for a wide range of disciplines." - Robert M. Clegg, Ph.D., Department of Physics, University of Illinois, Champaign-Urbana, Illinois "Overall this is a most welcome, and timely transformation of the classic, and most comprehensive textbook on fluorescence spectroscopy. It should be the number one item on the shopping list for any student or researcher involved in any aspect of fluorescence, be it as a biologist who does some microscopy, or a chemist synthesizing novel fluorophores." - Alan Ryder, Ph.D., National Centre for Biomedical Engineering Science, National University of Ireland-Galway, Galway, Ireland From the reviews of the third edition: "This book gives an overview of the principles and applications of fluorescence. It is well structured, starting with basic knowledge about the phenomena of fluorescence and ending with the latest applications. … highly readable and informative both by novices and by experienced people. … a helpful work of reference and a wonderful creation for learning and teaching. The updated 3rd edition with its appealing design and its absolutely up-to-date and, nevertheless, complete treatment of fluorescence spectroscopy makes it essential for everyone working in this field." (Christiane Albrecht, Analytical and Bioanalytical Chemistry, Vol. 390, 2008)Table of Contentsto Fluorescence.- Instrumentation for Fluorescence Spectroscopy.- Fluorophores.- Time-Domain Lifetime Measurements.- Frequency-Domain Lifetime Measurements.- Solvent and Environmental Effects.- Dynamics of Solvent and Spectral Relaxation.- Quenching of Fluorescence.- Mechanisms and Dynamics of Fluorescence Quenching.- Fluorescence Anisotropy.- Time-Dependent Anisotropy Decays.- Advanced Anisotropy Concepts.- Energy Transfer.- Time-Resolved Energy Transfer and Conformational Distributions of Biopolymers.- Energy Transfer to Multiple Acceptors in One,Two, or Three Dimensions.- Protein Fluorescence.- Time-Resolved Protein Fluorescence.- Multiphoton Excitation and Microscopy.- Fluorescence Sensing.- Novel Fluorophores.- DNA Technology.- Fluorescence-Lifetime Imaging Microscopy.- Single-Molecule Detection.- Fluorescence Correlation Spectroscopy.- Radiative Decay Engineering: Metal-Enhanced Fluorescence.- Radiative-Decay Engineering: Surface Plasmon-Coupled Emission.

    15 in stock

    £98.99

  • Cambridge University Press Cellular Biophysics and Modeling

    2 in stock

    Book SynopsisAn integrated guide to cellular biophysics and nonlinear dynamics, introducing students to the mathematical modeling of excitable cells. It combines empirical physiology and mathematical theory to present key interdisciplinary tools, highlighting how quantitative approaches can complement and advance bench research.Trade Review'In this text, Conradi Smith does an excellent job of teaching students with no mathematical training beyond calculus how to use differential equations to understand the basic principles of cell physiology and excitability. He skilfully walks students through the steps of modeling and analysis, all the while working to develop intuition and insight into how things work. His emphasis on computational methods for solution as well as graphical and geometrical means for interpretation enables him to communicate complex ideas in understandable ways. Furthermore, his patience and attention to detail will be appreciated by those students who have not had extensive exposure to the art of mathematical modeling. This text is a wonderful addition to the mathematical biology textbook literature.' James P. Keener, University of UtahTable of Contents1. Introduction; Part I. Models and Odes: 2. Compartmental modeling; 3. Phase diagrams; 4. Ligands, receptors and rate laws; 5. Function families and characteristic times; 6. Bifurcation diagrams of scalar ODEs; Part II. Passive Membranes: 7. The Nernst equilibrium potential; 8. The current balance equation; 9. GHK theory of membrane permeation; Part III. Voltage-Gated Currents: 10. Voltage-gated ionic currents; 11. Regenerative ionic currents and bistability; 12. Voltage-clamp recording; 13. Hodgkin-Huxley model of the action potential; Part IV. Excitability and Phase Planes: 14. The Morris-Lecar model; 15. Phase plane analysis; 16. Linear stability analysis; Part V. Oscillations and Bursting: 17. Type II excitability and oscillations; 18. Type I excitability and oscillations; 19. The low-threshold calcium spike; 20. Synaptic currents.

    2 in stock

    £118.75

  • Cambridge University Press Why Dna

    15 in stock

    Book SynopsisInformation is central to the evolution of biological complexity, a physical system relying on a continuous supply of energy. Biology provides superb examples of the consequent Darwinian selection of mechanisms for efficient energy utilisation. Genetic information, underpinned by the Watson-Crick base-pairing rules is largely encoded by DNA, a molecule uniquely adapted to its roles in information storage and utilisation.This volume addresses two fundamental questions. Firstly, what properties of the molecule have enabled it to become the predominant genetic material in the biological world today and secondly, to what extent have the informational properties of the molecule contributed to the expansion of biological diversity and the stability of ecosystems. The author argues that bringing these two seemingly unrelated topics together enables Schrödinger''s What is Life?, published before the structure of DNA was known, to be revisited and his ideas examined in the context of our current biological understanding.Trade Review'The essence of the book is in its title. The DNA structures and topology are described so clearly that the reader perceives these intricacies as pure evolutionary elegance, and understands WHY it is only in its balance of stability and agility that life could have started its journey. This book explains how DNA has become the fascinating prism, made of a fabric of complexity and information, into which the living reflects itself. My opinion is passionate because I have been thinking about the same problems for decades, and here I find many of the answers. Especially: what makes DNA so unique? It is a text that I keep reading over again.' Ernesto Di Mauro, IBPM, National Research Council, Rome'In What Is Life? Schrödinger conjectured that, in animate matter, order is derived from order, foreshadowing the discovery of DNA structure. Why DNA? is about this molecule and its dual information content - in linear genetic code and in thermodynamics of three-dimensional DNA structures. It addresses how DNA's intrinsic order led to complex, highly ordered living organisms, in a world that strives towards disorder. Why would DNA supplant RNA in carrying hereditary information during biological evolution? Why did multicellular organisms emerge, since natural selection favours the fittest, such as simple bacteria? What is complexity, and what has it to do with Bayesian logic? How do complexity, information and energy interrelate? This is a succinct discourse on Schrödinger's question, expanding from molecular interactions and genome cooperation to ecological systems and societal evolution. A must-read for biology scholars, and anyone interested in life's origins, biological evolution and the interface of biology and physics.' Georgi Muskhelishvili, Agricultural University of Georgia, TbilisiTable of ContentsAcknowledgements; Preface; 1. The perennial question; 2. The nature of information – information, complexity and entropy; 3. DNA – the molecule; 4. The evolution of biological complexity; 5. Cooperating genomes; 6. DNA, information and complexity; 7. Origins; 8. The complexity of societies; 9. Why DNA – and not RNA?; General reading and bibliography.

    15 in stock

    £49.39

  • Cambridge University Press The Fluid Dynamics of Cell Motility

    15 in stock

    Book SynopsisFluid dynamics plays a crucial role in many cellular processes, including the locomotion of cells such as bacteria and spermatozoa. These organisms possess flagella, slender organelles whose time periodic motion in a fluid environment gives rise to motility. Sitting at the intersection of applied mathematics, physics and biology, the fluid dynamics of cell motility is one of the most successful applications of mathematical tools to the understanding of the biological world. Based on courses taught over several years, it details the mathematical modelling necessary to understand cell motility in fluids, covering phenomena ranging from single-cell motion to instabilities in cell populations. Each chapter introduces mathematical models to rationalise experiments, uses physical intuition to interpret mathematical results, highlights the history of the field and discusses notable current research questions. All mathematical derivations are included for students new to the field, and end-of-Table of ContentsPart I. Fundamentals: 1. Biological background; 2. The fluid dynamics of microscopic locomotion; 3. The waving sheet model; 4. The squirmer model; Part II. Cellular locomotion: 5. Flagella and the physics of viscous propulsion; 6. Hydrodynamics of slender filaments; 7. Waving of eukaryotic flagella; 8. Rotation of bacterial flagellar filaments; 9. Flows and stresses induced by cells; Part III. Interactions: 10. Swimming cells in flows; 11. Self-propulsion and surfaces; 12. Hydrodynamic synchronisation; 13. Diffusion and noisy swimming; 14. Hydrodynamics of collective locomotion; 15. Locomotion and transport in complex fluids; References; Index.

    15 in stock

    £80.75

  • Cambridge University Press The Handbook of Medical Image Perception and Techniques

    5 in stock

    Book SynopsisA state-of-the-art review of key topics in medical image perception science and practice, including associated techniques, illustrations and examples. This second edition contains extensive updates and substantial new content. Written by key figures in the field, it covers a wide range of topics including signal detection, image interpretation and advanced image analysis (e.g. deep learning) techniques for interpretive and computational perception. It provides an overview of the key techniques of medical image perception and observer performance research, and includes examples and applications across clinical disciplines including radiology, pathology and oncology. A final chapter discusses the future prospects of medical image perception and assesses upcoming challenges and possibilities, enabling readers to identify new areas for research. Written for both newcomers to the field and experienced researchers and clinicians, this book provides a comprehensive reference for those interesTrade Review'In The Handbook of Medical Image Perception and Techniques, Samei and Krupinski have assembled a group of internationally-recognized experts to address an important but under-emphasized stage in the process of medical imaging.' William Hendee, Distinguished Professor Emeritus, Medical College of Wisconsin'A concise text that offers a unique collection of chapters from all the leading authors in medical perception. I would highly recommend this text for anyone wanting to know more about medical perception from its historical perspective to current research. A must have reference for anyone wanting to join in this exciting discipline.' Lonie R. Salkowski, University of Wisconsin, Madison'Drs Elizabeth Krupinski and Ehsan Samei have given us a wonderful new edition of their landmark textbook on medical image perception, with updated chapters throughout and with approximately thirty percent new material added since the first edition was published in 2010. This new volume comprehensively updates and extends the 'keystone' publication in the field of medical image perception research. Each chapter is the definitive reference on its topic, authored by a foremost expert. With this new edition, Drs Krupinski and Samei have assembled a compendium of what amounts to decades of research and accumulated wisdom in a compact package-comprehensive and yet still very accessible for a broad audience. … Anyone with an interest in this topic will find this book to be an invaluable resource.' Michael A. Bruno, Pennsylvania State UniversityTable of Contents1. Medical image perception Ehsan Samei and Elizabeth Krupinski; 2. A short history of image perception in medical radiology Harold Kundel and Calvin Nodine; 3. Spatial vision research without noise Arthur Burgess; 4. Signal detection theory – a brief history Arthur Burgess; 5. Signal detection in radiology Arthur Burgess; 6. Lessons from dinners with the giants of modern image science Robert Wagner; 7. Perception in context David Manning; 8. Perceptual factors in reading medical images Elizabeth A Krupinski; 9. Cognitive factors in reading medical images David Manning; 10. Satisfaction of search in radiology Kevib Berbaum, Edmund Franken, Robert Caldwell, Kevin Schartz and Mark Madsen; 11. Acquiring expertise in radiologic image interpretation Calvin F. Nodine and Claudia Mello-Thoms; 12. The first moments of medical image perception Jeremy M. Wolfe, Karla K. Evans and Trafton Drew; 13. Image quality and its clinical relevance Justin Solomon, Robert Saunders, Jr and Ehsan Samei; 14. Designing perception experiments Ehsan Samei; 15. Receiver operating characteristic analysis: basic concepts and practical applications Georgia Tourassi; 16. Multireader ROC analysis Stephen L. Hillis; 17. Memory effects and experimental design Tamara Miner Haygood and Karla K. Evans; 18. Observer models as a surrogate to perception experiments Craig K. Abbey and Miguel P. Eckstein; 19. Implementation of observer models Matthew A. Kupinski; 20. Value and limitations of observer models Lucretiu M. Popescu; 21. Perception of volumetric data Geoffrey D. Rubin, Trafton Drew and Lauren H. Williams; 22. Performance assessment using standardized data sets: the PERFORMS® scheme in breast screening and other domains Yan Chen and Alastair Gale; 23. Breast screen reader assessment strategy (BREAST): a research infrastructure with a translational objective Patrick Brennan, Lee Warwick and Kriscia Tapia; 24. CAD: an image perception perspective Maryellen Giger and Weijie Chen; 25. Common designs of CAD studies Yulei Jiang; 26. Evaluation of CAD and radiomic tools Berkman Sahiner and Nicholas Petrick; 27. Quantitative imaging – images to numbers Daniel C. Sullivan and Edward F. Jackson; 28. Optimization of 2D and 3D radiographic imaging systems Jeffrey H. Siewerdsen; 29. Display optimization from a physics perspective Alisa Walz-Flannigan and Scott Stekel; 30. Display optimisation from a perception perspective Mark Mcentee and Rachel Toomey; 31. Perception and training William F. Auffermann and Maciej Mazurowski; 32. Ergonomics 2.0: fatigue in medical imaging Sian Taylor-Phillips, Chris Stinton and Elizabeth Krupinski; 33. Perception issues in pathology Liron Pananowitz, Claudia Mello-Thoms and Elizabeth A. Krupinski; 34. Medical image perception from a clinical perspective Francine L. Jacobson; 35. Future of medical image perception Elizabeth A. Krupinski and Ehsan Samei.

    5 in stock

    £133.95

  • Why DNA

    Cambridge University Press Why DNA

    15 in stock

    Book SynopsisInformation is central to the evolution of biological complexity, a physical system relying on a continuous supply of energy. Biology provides superb examples of the consequent Darwinian selection of mechanisms for efficient energy utilisation. Genetic information, underpinned by the Watson-Crick base-pairing rules is largely encoded by DNA, a molecule uniquely adapted to its roles in information storage and utilisation.This volume addresses two fundamental questions. Firstly, what properties of the molecule have enabled it to become the predominant genetic material in the biological world today and secondly, to what extent have the informational properties of the molecule contributed to the expansion of biological diversity and the stability of ecosystems. The author argues that bringing these two seemingly unrelated topics together enables Schrödinger''s What is Life?, published before the structure of DNA was known, to be revisited and his ideas examined in the context of our currenTrade Review'The essence of the book is in its title. The DNA structures and topology are described so clearly that the reader perceives these intricacies as pure evolutionary elegance, and understands WHY it is only in its balance of stability and agility that life could have started its journey. This book explains how DNA has become the fascinating prism, made of a fabric of complexity and information, into which the living reflects itself. My opinion is passionate because I have been thinking about the same problems for decades, and here I find many of the answers. Especially: what makes DNA so unique? It is a text that I keep reading over again.' Ernesto Di Mauro, IBPM, National Research Council, Rome'In What Is Life? Schrödinger conjectured that, in animate matter, order is derived from order, foreshadowing the discovery of DNA structure. Why DNA? is about this molecule and its dual information content - in linear genetic code and in thermodynamics of three-dimensional DNA structures. It addresses how DNA's intrinsic order led to complex, highly ordered living organisms, in a world that strives towards disorder. Why would DNA supplant RNA in carrying hereditary information during biological evolution? Why did multicellular organisms emerge, since natural selection favours the fittest, such as simple bacteria? What is complexity, and what has it to do with Bayesian logic? How do complexity, information and energy interrelate? This is a succinct discourse on Schrödinger's question, expanding from molecular interactions and genome cooperation to ecological systems and societal evolution. A must-read for biology scholars, and anyone interested in life's origins, biological evolution and the interface of biology and physics.' Georgi Muskhelishvili, Agricultural University of Georgia, TbilisiTable of ContentsAcknowledgements; Preface; 1. The perennial question; 2. The nature of information – information, complexity and entropy; 3. DNA – the molecule; 4. The evolution of biological complexity; 5. Cooperating genomes; 6. DNA, information and complexity; 7. Origins; 8. The complexity of societies; 9. Why DNA – and not RNA?; General reading and bibliography.

    15 in stock

    £20.99

  • Cambridge University Press Quantum Chemistry Simulation of Biological Molecules

    3 in stock

    Book SynopsisThis book describes the quantum chemical simulation of a wide variety of molecular systems, with detailed analysis of their quantum chemical properties, individual molecular configurations, and cutting-edge biomedical applications.Trade Review'Recommended.' J. A. Kelly, Choice ConnectTable of Contents1. Basic Properties of Quantum Chemistry; 2. Charge Transport in the DNA Molecule; 3. Electronic Transmission Spectra of the DNA Molecule; 4. Thermodynamic Properties of the DNA Molecule; 5. Properties of the DNA/RNA Nucleobases; 6. Molecular Electronics; 7. Amino Acids Anhydrous Crystals; 8. Protein-Protein Systems; 9. Ascorbic Acid and Ibuprofen Drugs; 10. Cholesterol-lowering Drugs; 11. Collagen-based Biomaterials; 12. Anti-Migraine Drugs; 13. Anti-Parkinson Drugs; 14. Central Nervous System Disorders; 15. The Biology of Cancer; Notes; References; Index.

    3 in stock

    £63.64

  • Neutrinos: Discovery, Detection & New

    Nova Science Publishers Inc Neutrinos: Discovery, Detection & New

    1 in stock

    Book SynopsisThe idea of a neutrino was derived from experiments demonstrating continuous beta decay spectra and, at the same time, it resolved problems that had arisen in the determination of nuclear constituents. The unusual features of the neutron, especially its disintegration, led to the introduction and subsequent detection of a new particle, the neutrino. In this book, the authors present current research in the study of the discovery, detection and new developments in neutrinos. Topics include the way to a deterministic tachyon model of neutrino; neutrino emissivity and light species; and the magnetic moment and electric dipole moment of Tau-neutrinos.

    1 in stock

    £73.49

  • Research Progress in Chemical Physics &

    Nova Science Publishers Inc Research Progress in Chemical Physics &

    2 in stock

    Book SynopsisPreface; Ozonation of Hydrocarbons; Synthesis & Investigation Properties of Epoxy Containing Compounds & Composite Materials on their Basis; Biodegradable Binary & Ternary Blends of Cellulose & Ethyl Cellulose with Synthetic & Natural Polymers; Hydrosilylation Reactions of Polymethylhydrosiloxane with Acrylates & Methacrylates & Solid Polymer Electrolyte Membranes on their Basis; Biodetoxication of Aromatic Hydrocarbons in Aqueous Media; Modern Immunochemical & Biosensor Technologies for Analysis of Environmental Ecotoxicants; Poly (3-Hydroxybutyrate) with Ethylene-Propylene Copolymer Blends: Structure & Calorimetry Properties; Adaptogens Decrease the Generation of Reactive Oxygen Species by Mitochondria; Quantum-Chemical Calculation of Some Molecules Aromatic Olefines by the Method MNDO; Formation of Ozonides & their Stability in the Process of Unsaturated Polymers In Latex; Structures (Monomer & Dimer) of Sodium & Potassium 2-(N-Methylamide)-2-(3'',5''-Di-Tert.Butyl-4-Hydroxybenzyl)-Malonates & Biological Properties; Reaction of Ozone with Some Oxygen-Containing Organic Compounds; Enhanced Oil Recovery Using Binary Mixture (BM) Reaction Products as an Alternative to Increasing Reservoir Water Content; Assessment of the Potential of Enhanced Oil Recovery from Reservoirs with High Water Content Using the Heat of Nitrate Oxidation Reactions & In Situ Hydrocarbon Oxidation; Blends of Poly(3-Hydroxybutyrate) with an Ethylene-Propylene Copolymer; Kinetics of Photoinitiated Copolymerization of Bifunctional (Meth)Acrylates till High Conversion: Numerical Verification of Kinetic Model of the Process; Degradation of Films Based on Mixtures of Vinyl Alcohol with Vinyl Acetate Copolymers & Polyhydroxybutyrate under UV-Radiation; Nanofibrous Polyhydroxybutyrate-Based Biomaterials; Influence of Aminoalkoxy- & Glycidoxyalkoxysilanes on Adhesion Characteristics of Ethylene Copolymers; The Study of Influence of Dihydroquercetin & Cyclodextrin Inclusion Complex with the New Dihydroquercetin Derivative on Ozone Oxidation of Fibrinogen; Challenges & Development Perspectives on Nanopatterned Implants Loaded with Drugs; The Structural Analysis of Nanocomposites Polymer/Organoclay Flame-Resistance; The Regularity of Cracks Formation on Vulcanized Elastomers under Ozone Action: Polyisoprene; The Evaluation of Efficiency of Deposition of Dispersed Particles in Inertial Dust Separator; Comparative Evaluation of Viability of Cells of Probiotic Strains by Luminescence Microscopy & Flow Cytometry; The Interrelation Structure & Thermodynamic Properties in the Five-Membered O- & N-Heterocyclic Compounds; Thermodynamic Properties & Structure of Heteroatom Derivatives of Indene; Development of Thermoplastic Vulcanizates Based on Isotactic Polypropylene & Ethylene-Propylene-Diene Elastomer; Conclusion; Index.

    2 in stock

    £215.99

  • Nonequilibrium Statistical Mechanics

    Oxford University Press Nonequilibrium Statistical Mechanics

    15 in stock

    Book SynopsisThis book presents the main principles and methods of nonequilibrium statistical mechanics, a topic studied by both chemists and physicists. This book is written for graduate students and scientists who already have knowledge of basic equilibrium statistical mechanics and who are interested in the more complex field of time-dependent nonequilibrium statistical mechanics.Table of Contents1. Brownian Motion and Langevin equations ; 2. Fokker-Planck equations ; 3. Master equations ; 4. Reaction rates ; 5. Kinetic models ; 6. Quantum dynamics ; 7. Linear response theory ; 8. Projection operators ; 9. Nonlinear problems ; 10. The paradoxes of irreversibility ; Appendices

    15 in stock

    £140.00

  • Cellular Biophysics Transport Volume 1 A Bradford Book

    Penguin Random House LLC Cellular Biophysics Transport Volume 1 A Bradford Book

    15 in stock

    15 in stock

    £73.81

  • Principles of Analytical Electron Microscopy

    Springer Principles of Analytical Electron Microscopy

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £123.49

  • Practical Stereology

    Springer Practical Stereology

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £123.49

  • Mechanistic Approaches to Interactions of Electric and Electromagnetic Fields with Living Systems

    Springer Mechanistic Approaches to Interactions of Electric and Electromagnetic Fields with Living Systems

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £170.99

  • Lipid and Biopolymer Monolayers at Liquid Interfaces

    Springer Lipid and Biopolymer Monolayers at Liquid Interfaces

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £170.99

  • The Science of Photobiology

    Springer The Science of Photobiology

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £123.49

  • The Science of Photobiology

    Springer The Science of Photobiology

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £123.49

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