Vaccination Books

13 products


  • Vax-Unvax: Let the Science Speak

    Skyhorse Publishing Vax-Unvax: Let the Science Speak

    15 in stock

    Book SynopsisNEW YORK TIMES BESTSELLER! The Studies the CDC Refuses to Do This book is based on over one hundred studies in the peer-reviewed literature that consider vaccinated versus unvaccinated populations. Each study is analyzed, and health differences among infants, children, and adults who have been vaccinated and those who have not are presented and put in context. Readers will find information on: The infant/child vaccination schedule Thimerosal in vaccines Live virus vaccines The human papillomavirus (HPV) vaccine Vaccination and Gulf War illness Influenza (flu) vaccines Hepatitis B vaccination The COVID-19 vaccine Vaccines during pregnancy Given the massive push to vaccinate the entire global population, this book is timely and necessary for individuals to make informed choices for themselves and their families. Trade Review“Millions of people—myself included—initially believed the Covid-19 vaccine disaster to be a one-off, the result of a novel, rapidly evolving virus combined with a rushed therapeutic packaged in an experimental delivery system. Today I laugh at such naiveté. In Vax-Unvax, Kennedy and Hooker shine a blinding light on the appalling lack of research and blatant propaganda behind the entire inflated and ever-expanding childhood vaccine schedule. The authors’ painstaking investigation and rigorous analyses are rivaled only by their bravery in exposing the depth and breadth of the lies we’ve been told. As a physician who never dreamed of questioning the safety and efficacy claims of routine immunizations and who believed he was protecting his patients and his own children by endorsing them, I am humbled and enraged. Our government, the media, and the powerful and rapacious pharmaceutical industrial complex have deceived, endangered, and gaslit the public for far too long. I hope this explosive and important book finds a worldwide audience and becomes a staple in every pediatrician’s and parent’s library.”—Dr. Pierre Kory, author of The War on Ivermectin, cofounder of the Front Line Covid-19 Critical Care Alliance, cofounder of the Leading Edge Tele-Health Clinic “As the threat of fatal infectious diseases in childhood has dissipated, there has been a lagged increase in the intensity of vaccination for rare illnesses. Modern treatment and supportive care have taken much of the concern out of the infections on the childhood vaccine schedule. However, with the rise of hyper-vaccination, Kennedy and Hooker uncover a concurrent explosion of childhood allergic, immune, and neuropsychiatric illnesses. Massive systemic perturbation of the immune system with indiscriminate immunization has come at a sobering cost. Read Vax-Unvax carefully and keep it close at hand—this dawn of a new age in public health will be tumultuous for years to come.”—Dr. Peter McCullough, author of The Courage to Face COVID-19 “In this book, Kennedy and Hooker provide the complete, definitive demolition of the mythos and propaganda that tells the public vaccines improve the health of children. Not a plank of this false house remains by the end of this book. The lies are dismantled in cool, clear language void of bombast, which allows the facts, figures, and data to shine through, to a devastating conclusion. This is the book you can hand to people who are still in trance states about vaccines.”—Celia Farber, journalist and author of Serious Adverse Events “‘The Science’ is finally here in one place. If you want to follow the science related to vaccines and health problems, this is a must read. With over one hundred references, the actual harm being caused by vaccines is exposed. Parents, don't listen to an authority figure without doing your own research. This book is required reading for every informed parent.”—Paul Thomas, MD, author of The Vaccine-Friendly Plan and The Addiction Spectrum; founder and host of With the Wind: Science Revealed; cofounder KidsFirst4Ever.com “This clear, compelling, timely book lays to rest most myths about the ‘science’ and safety of many existing vaccines and exposes shoddy testing, shocking damage to health, and corrupt business practices. An important follow-up to Kennedy’s The Real Anthony Fauci.”—Naomi Wolf, bestselling author of The Beauty Myth and The Bodies of Others “While the CDC continues to refuse to do the type of vaccinated versus unvaccinated study that parents have long been demanding, independent researchers have forged ahead, and the results are now quite clear: unvaccinated children are healthier. In Vax-Unvax: Let the Science Speak, Robert F. Kennedy Jr. and Dr. Brian Hooker review that data as well as many additional studies comparing health outcomes between those who did or did not receive individual vaccines. This is an essential resource for the serious researcher and a valuable guide for anyone wishing to exercise truly informed consent. The graphs helpfully included with the discussion of each study covered speak for themselves. It is past time for the ‘public health’ establishment to stop deceiving the public with their proclamations of official dogma about the ostensible safety of these pharmaceutical products.”—Jeremy R. Hammond, independent journalist and author of The War on Informed Consent “In 1999, I gave a vaccine that caused such a bad side effect that it altered the trajectory of my patient’s life. Thus began my journey into vaccine safety research. This book is a great compilation of scientific studies you never heard about on the news. With easy-to-understand graphics and explanations of statistics, you can analyze data from clinicians and researchers from around the world. You may find yourself doubting the simplistic ‘safe and effective’ doctrine repeated by health authorities. You will find yourself more empowered to make vaccine decisions for your child.”—Elizabeth Mumper, MD, IFMCP, president & CEO, Rimland Center for Integrative Medicine “RFK Jr. and Dr. Hooker present the science that supports what I have personally witnessed in my twenty-five years as a pediatrician—unvaccinated children are healthier and have fewer chronic medical problems compared to vaccinated kids. Today’s parents, and a growing number of my colleagues, are now coming to recognize this grand irony in our modern pediatric health care system."—Dr. Bob Sears, author of The Vaccine Book and host of TheVaccineConversation.com podcast “Bobby Kennedy and Brian Hooker are tireless heroes on the front line of a great battle to protect our health freedom. Biomedical studies are being falsified and the masses are being deceived by health authorities, the vaccine industry, and a complicit media. Read this book and let the true science speak!” —Neil Z. Miller, author of Miller's Review of Critical Vaccine Studies “When I met Dr. Hooker on August 29, 2014, he was more than a decade into his relentless efforts through the Freedom of Information Act (FOIA) to reveal not only the studies the CDC refused to do but the plague of corruption surrounding CDC whistleblower William Thompson’s confession regarding the censorship and fraud in the MMR vaccine trial by the CDC to cover up the fraud in the in clinical literature surrounding all vaccines. Stunned by the blatant corruption in Dr. Hooker’s presentation that day, Kent Heckenlively and I, in collaboration with Robert F. Kennedy Jr., began to write Plague of Corruption. Throughout 2019, Dr. Hooker and Kennedy collaborated to reveal much of the CDC, FDA, and NIH corruption in the thirty-four page foreword to Plague of Corruption that revealed manipulation of hundreds of basic research studies showing dangers of xenotransplantation, microbial contamination, and environmental toxins including mercury, aluminum, PEG, and the corruption of the agencies tasked to protect public health. Vax-Unvax is the result of their heroic effort to reveal the censored science and truth behind the role of a failure by these agencies tasked to conduct safety studies in three decades of liability-free vaccines and the resultant explosion of chronic disease and disability facing our world today. Given the massive push to vaccinate a new generation, this book is a must read supporting a moratorium on inoculations in favor of oral and mucosal immunization strategies.”—Judy A. Mikovits, PhD “In Vax-Unvax: Let the Science Speak, authors Robert F. Kennedy, Jr. and Brian Hooker have provided a deep dive into vaccine safety by looking at published data from independent researchers. The resulting review of vaccinated and unvaccinated children's health outcomes clearly shows the damage, much of it neurological, that blind adherence to the CDC's current vaccine schedule can induce. The studies highlighted are those that both the FDA and CDC have routinely refused, and continue to refuse, to do themselves. The official reason for not providing such studies is based on the erroneous notion that conducting vaccinated-unvaccinated evaluations would somehow be ‘unethical.’ Kennedy and Hooker demolish this argument and then proceed to review the safety of different vaccines, many that contain adjuvant aluminum or Thimerosal, the latter an ethyl mercury compound. Overall, for those trying to understand the often-confusing claims and counterclaims, particularly lay people, the book provides some badly needed clarity. The book also considers the current Covid-19 mRNA vaccines in context to the older childhood vaccine platforms. This is a particularly timely contribution in that the Covid-19 pandemic and resulting vaccine mandates have paradoxically served to make more people question the official ‘safe and effective’ mantra that tends to surround all vaccines: If the conventional vaccine platforms using compounds with aluminum and mercury are not safe, then why should anyone trust the completely new and largely experimental vaccine platforms developed for Covid (and soon numerous vaccines)? For parents it can be both confusing and frightening to consider the pros and cons of vaccines against childhood diseases: What if they make the wrong decision, in either direction, and their child is harmed? While many in the medical profession may not like the book because it exposes the outright deception of the pharmaceutical industry, the CDC and FDA, I strongly believe that many parents, or parents-to-be, will be grateful for the information it contains. Simply put, at the end of the day the ability to consider all aspects of vaccine safety in order to make an informed choice for one's children, or oneself, is an absolutely critical aspect of real health freedom. In turn, health freedom is intimately tied to the concept of ‘security of the person,’ perhaps the most fundamental of natural rights. Kennedy and Hooker should be commended for tackling this crucial issue in order to bring clarity to the mass of ‘dis-’ and ‘mis-’ information peddled by the health establishment and the mainstream media. If indeed the ‘truth can set you free,’ then this book is a huge step in the right direction.”—Christopher Shaw, neuroscientist and professor of ophthalmology at University of British Columbia, author of Dispatches from the Vaccine Wars “If there is only one book you read in your entire life, let it be this one! If you want the science to speak . . . then have the courage to look at the actual science, data, and truth found in the pages of Vax-Unvax. Arm yourself with the information that puts the power back into the hands of parents where it belongs, not in the hands of corrupt Pharma, captured government officials, and incentivized doctors spouting catch phrases with little to no evidence to back it up. RFK Jr. and Dr. Brian Hooker are the bold voices of truth, presenting evidence that cannot be disputed. The main purpose of a parent is to love your child and keep them safe. If you have not had the courage before, I boldly implore you to find the courage now, and educate before you vaccinate!”—Leigh-Allyn Baker, actress, producer, and star of the global hit Good Luck Charlie

    15 in stock

    £21.25

  • Edward Jenner: The Vaccination Visionary

    The History Press Ltd Edward Jenner: The Vaccination Visionary

    3 in stock

    Book SynopsisEdward Jenner is a giant of modern medicine. Throughout history, smallpox had plagued humanity with disfigurement, blindness and death. It was an incurable blight, the suffering of which Jenner helped to end.Surmising from the immunity of milkmaids that cowpox might be some defence against the ravages of smallpox, in 1793 he took some of the matter from a human case of cowpox and inserted it into the arm of a young boy. To test this, the first human-to-human vaccination, he subsequently inoculated the boy with smallpox itself, and found him to be immune from the disease. In 1979 smallpox was declared extinct.In this concise biography, Rob Boddice tells the story of Jenner’s life, his medical vision and his profound legacy. It is a story that encompasses revolutions in medical experimentation, public health provision and the prevention of other diseases, from anthrax to measles, but above all it highlights the profound impact that Jenner’s vision has had upon humanity’s battle against disease.

    3 in stock

    £10.44

  • Sexualizing Cancer

    The University of Chicago Press Sexualizing Cancer

    15 in stock

    Book SynopsisThe virus that changed how we think about cancer and its culpritsand the vaccine that changed how we talk about sex and its risks. Starting in 2005, people in the US and Europe were inundated with media coverage announcing the link between cervical cancer and the sexually transmitted virus HPV. Within a year, product ads promoted a vaccine targeting cancer's viral cause, and girls and women became early consumers of this new cancer vaccine. An understanding of HPV's broadening association with other cancers led to the identification of new at-risk populationsnamely boys and menand ignited a plethora of gender and sexual issues related to cancer prevention. Sexualizing Cancer is the first book dedicated to the emergence and proliferation of the HPV vaccine along with the medical capacity to screen for HPVcrucial landmarks in the cancer prevention arsenal based on a novel connection between sex and chronic disease. Interweaving accounts from the realms of biomedical science, publiTrade Review“An engaging, informative, and exceptionally erudite effort to explicate and analyze the complex, decades-long intertwining of HPV, cancer, gender, and sexuality. Sexualizing Cancer will be a welcome resource for scholars, clinicians, and policymakers.” -- Laura M. Carpenter, Vanderbilt University“Mamo has put together an exciting and lively read, highlighting historically through to the present day the many ways in which assumptions about gender and sexuality underpin much of public health decision making. With a focus on HPV, she sets out an extremely compelling and well written narrative that places current debates within their larger economic, social, cultural, and political contexts. Weaving together the local and the global, she ultimately asks us to query how our own assumptions about gender, sexuality, race, and class impact how we read and understand public health, and the social connections and actions we take.” -- Sofia Gruskin, University of Southern CaliforniaTable of ContentsIntroduction: The Sexual Politics of Cancer and a New Regime of Cancer Prevention Chapter One: Producing and Protecting Risky Girls Chapter Two: “What’s In It for the Boys?” Chapter Three: The Cancer That Dare Not Speak Its Name Chapter Four: A Tale of Two Trials: Settling Debate through Evidence-Based Medicine Chapter Five: A “Coming Epidemic” of HPV-Associated Oral Cancer Chapter Six: Sex at the Oncology Office: Oral Cancer Care and the Politics of Prevention Chapter Seven: Cervical Cancer’s Screening Politics Chapter Eight: The Precision Imaginary: Optimizing Cancer Prevention Tools Chapter Nine: Commodities of Sexual Health Care Acknowledgments Notes Bibliography Index

    15 in stock

    £80.75

  • Sexualizing Cancer  HPV and the Politics of

    The University of Chicago Press Sexualizing Cancer HPV and the Politics of

    15 in stock

    Book SynopsisTrade Review“An engaging, informative, and exceptionally erudite effort to explicate and analyze the complex, decades-long intertwining of HPV, cancer, gender, and sexuality. Sexualizing Cancer will be a welcome resource for scholars, clinicians, and policymakers.” -- Laura M. Carpenter, Vanderbilt University“Mamo has put together an exciting and lively read, highlighting historically through to the present day the many ways in which assumptions about gender and sexuality underpin much of public health decision making. With a focus on HPV, she sets out an extremely compelling and well written narrative that places current debates within their larger economic, social, cultural, and political contexts. Weaving together the local and the global, she ultimately asks us to query how our own assumptions about gender, sexuality, race, and class impact how we read and understand public health, and the social connections and actions we take.” -- Sofia Gruskin, University of Southern CaliforniaTable of ContentsIntroduction: The Sexual Politics of Cancer and a New Regime of Cancer Prevention Chapter One: Producing and Protecting Risky Girls Chapter Two: “What’s In It for the Boys?” Chapter Three: The Cancer That Dare Not Speak Its Name Chapter Four: A Tale of Two Trials: Settling Debate through Evidence-Based Medicine Chapter Five: A “Coming Epidemic” of HPV-Associated Oral Cancer Chapter Six: Sex at the Oncology Office: Oral Cancer Care and the Politics of Prevention Chapter Seven: Cervical Cancer’s Screening Politics Chapter Eight: The Precision Imaginary: Optimizing Cancer Prevention Tools Chapter Nine: Commodities of Sexual Health Care Acknowledgments Notes Bibliography Index

    15 in stock

    £26.60

  • Preventable

    Penguin Books Ltd Preventable

    2 in stock

    Book Synopsis**THE SUNDAY TIMES BESTSELLER BBC RADIO 4 BOOK OF THE WEEK**The definitive story of COVID-19 and how global politics shape our health - from a world-leading expert and the pandemic''s go-to science communicator Professor Devi Sridhar has risen to prominence for her vital roles in communicating science to the public and speaking truth to power. In Preventable she highlights lessons learned from outbreaks past and present in a narrative that traces the COVID-19 pandemic - including her personal experience as a scientist - and sets out a vision for how we can better protect ourselves from the inevitable health crises to come.In gripping and heartfelt prose, Sridhar exposes the varied realities of those affected and puts you in the room with key decision makers at crucial moments. She vibrantly conveys the twists and turns of a plot that saw: deadlier varients emerge (contrary to the predictions of social media pundits who argued it would mutate to a milder form); countries with weak health systems like Senegal and Vietnam fare better than countries like the US and UK (which were consistently ranked as the most prepared); and the quickest development of game-changing vaccines in history (and their unfair distribution)Combining science, politics, ethics and economics, this definitive book dissects the global structures that determine our fate, and reveals the deep-seated economic and social inequalities at their heart - it will challenge, outrage and inspire.''A brutally compelling reminder that if voices like Devi''s had been listened to, so many more could have lived'' OWEN JONES''One of the most brilliant scientists in the world who has been proven consistently right in this crisis'' PIERS MORGAN''Excellent . . . Fair, clear and compelling'' NICOLA STURGEON''Those who have found Professor Devi Sridhar''s expertise and calm advice invaluable since the arrival of Covid-19 will be glad to know that she has written Preventable'' RACHEL COOKE, Guardian, Non-fiction to look out for in 2022Trade ReviewThe sensational story of how a disaster was turned into a catastrophe, with the clarity, precision and humanity that you would expect from one of the most important voices of reason of the COVID era. A brutally compelling reminder that if voices like Devi's had been listened to, so many more could have lived -- Owen JonesExcellent . . . Fair, clear and compelling. And like all of Devi's contributions over the course of the pandemic, very accessible -- Nicola SturgeonOne of the most brilliant scientists in the world who has been proven consistently right in this crisis -- Piers MorganPowerful . . . If we're to stop history from repeating itself when the next pandemic pathogen emerges, books such as Preventable are very much welcome -- Oliver Barnes * Financial Times *Contributions such as Devi's will be the building blocks of the learning we need, as a global community, to create the awareness required for the healthier and safer world all people deserve -- Dr Tedros, Director-General of the World Health OrganizationEssential reading -- Lorraine KellyDevi is a public health expert with deep knowledge and expertise in the field. She has a unique ability to translate complex public health challenges, research and recommendations into language experts and non-experts alike can understand. I always read and listen to what she has to say and I hope you will too -- Chelsea ClintonBrilliant. I read it like a thriller that I had lived through, a fascinating, detailed and personal account of the pandemic that takes you behind and beyond the headlines. I suspect it will be the most readable account of all the analyses that will follow -- Chris van TullekenSridhar's prescience transformed her into one of Britain's most prominent commentators once . . . In her new book, Preventable, Sridhar distils the lessons of the time -- George Eaton * New Statesman *Those who have found Professor Devi Sridhar's expertise and calm advice invaluable since the arrival of Covid-19 will be glad to know that she has written Preventable -- Rachel Cooke * Guardian, 'Nonfiction to look out for in 2022' *Devi Sridhar, professor of global public health at Edinburgh university, examines how the pandemic changed the world and how we might stop the next one happening * Financial Times, 'The books to read in 2022' *

    2 in stock

    £11.69

  • Antivaxxers How to Challenge a Misinformed

    MIT Press Ltd Antivaxxers How to Challenge a Misinformed

    10 in stock

    Book SynopsisA “clear and insightful” takedown of the anti-vaccination movement, from its 19th-century antecedents to modern-day Facebook activists—with strategies for refuting false claims of friends and family (Financial Times)Vaccines are a documented success story, one of the most successful public health interventions in history. Yet there is a vocal anti-vaccination movement, featuring celebrity activists (including Kennedy scion Robert F. Kennedy Jr. and actress Jenny McCarthy) and the propagation of anti-vax claims through books, documentaries, and social media. In Anti-Vaxxers, Jonathan Berman explores the phenomenon of the anti-vaccination movement, recounting its history from its nineteenth-century antecedents to today’s activism, examining its claims, and suggesting a strategy for countering them. After providing background information on vaccines and how they work, Berman describes resistance to Britain’s Vaccination Ac

    10 in stock

    £16.19

  • Vaccines For Dummies

    John Wiley & Sons Inc Vaccines For Dummies

    15 in stock

    Book SynopsisInoculate yourself againstthe confusion and misinformation surrounding vaccines Measles, mumps, and rubellaoh my!Why are we vaccinating our childrenand ourselvesagainstthese diseases, and what goes on inourbodies after the needlecomes out?Vaccines For Dummieswill inform and entertain you about allthingsvax, including how the first vaccines were discovered, what's in modern vaccines,how they aretested andapprovedfor use, and whytheCDC's vaccine schedule is what it is.Inside,you'llalso find a complete guide tovaccinebenefits,potential side effects,and contraindications, so you'll be readywhen shottime comes. Fromthe very firstinoculationshundreds of years ago to the brandnewCOVID-19 shot, creating immunity to diseases has become a human specialty.Ifyou'rewondering how safe and how necessary it all is, you aren't alone. InVaccinesForDummies,we'll explorethe issue from every angle, empowering you to take charge of your wellbeing.With this book, you will: Discoverthe ABCs of vaccines, including whatthey'remade of and how they workLearn abouteach recommended childhoodand adultimmunization, plus the seasonal flu shot, all with this evidence-based guideTake a journey through vaccine history,meeting the major players ofyesterday and todayDecide what's right for your family, with the help of the most recent vaccine science Parents,parents-to-be,adults of any age,and anyone who wants to delve into the microscopic world of pathogens and theirarch nemeses(antigens and antibodies)willget a doubledose of knowledge fromVaccinesForDummies.Table of ContentsIntroduction 1 About This Book 1 Foolish Assumptions 2 Icons Used in This Book 2 Beyond the Book 2 Where to Go from Here 3 Part 1: Getting Started with Vaccine Basics 5 Chapter 1: Focusing on Vaccine Fundamentals 7 Realizing the Crucial Role of Vaccines 8 Explaining How a Vaccine Works 9 Distinguishing between antigens and antibodies 10 Breaking down other vaccine ingredients 10 Comparing Viruses, Bacteria, and Toxins 11 Studying COVID-19 Vaccine Development 14 Understanding the Importance of Vaccine Schedules 15 Preparing for Potential Vaccine Side Effects 16 Optimizing Your Immune Response 16 Chapter 2: The (Non) Life of a Virus 17 Looking Inside Your Average Virus 18 Investigating Influenza Viruses 18 Type A 19 Type B 21 Type C 21 Type D 22 Examining Enteroviruses (Including Rhinoviruses) 22 Knowing About Norovirus 23 Understanding HIV 24 Trying to Say Goodbye to Measles 25 Checking Out the Cause of Chicken Pox: Varicella 26 Fighting Ebola 27 Surveying Variola (Smallpox) 29 Chapter 3: The Crowned Virus: Coronavirus 31 Identifying the Coronavirus in Humans 32 Combatting the Common Cold Coronavirus 33 What is a cold, exactly? 34 What causes a cold? 34 When is a cold not a cold? 35 Surveying SARS and MERS 40 Severe acute respiratory syndrome (SARS) 40 Middle East respiratory syndrome (MERS) 41 COVID-19: The Novel (and Specially Confounding) Coronavirus 42 Reviewing the start of the pandemic 42 Charting the course of the infection 44 Detecting a COVID-19 infection 46 Digging into the development of COVID-19 vaccines 50 Dealing with vaccine side effects 52 Aiming for herd immunity 53 Keeping safe from COVID-19 if you’re not yet protected by vaccination 55 Coping with COVID-19 and flu season 56 Chapter 4: Bacterial Bad Guys 57 Understanding What Makes Bacteria Different from Viruses 57 Digging into Vaccines That Defuse Bacteria 58 The make-up of vaccines that protect against bacterial toxins 59 The bacterial illnesses that vaccines prevent 59 Comparing Antibiotics and Vaccines 64 Seeing How Vaccines Help Prevent Antibiotic Resistance 65 Part 2: Verifying Valuable Vaccines 67 Chapter 5: Distinguishing and Testing Different Vaccines 69 Getting to Know the Different Types of Vaccines 70 Whole-pathogen vaccines 70 Subunit vaccines 72 Testing Vaccines for Safety and Effectiveness 75 Determining the need and costs: The preclinical stage 75 Phase I 76 Phase II 76 Phase III 76 Post–Phase III 77 Studying the Efficacy of Vaccines 78 Measuring efficacy versus effectiveness 78 Rounding up herd immunity 79 Tracing the History of Various Vaccines 80 Smallpox 80 Typhoid fever 81 Yellow fever 81 Influenza 82 Polio 82 Anthrax 82 Measles, mumps, and rubella (MMR) 82 Varicella (chicken pox) 83 Chapter 6: Tracking the Current List of Effective Vaccines 85 Chicken Pox (Varicella) 85 Diphtheria, Tetanus, and Pertussis 86 Diphtheria 86 Tetanus 87 Pertussis 88 Haemophilus Influenzae Type B (Hib) 88 Hepatitis A 89 Hepatitis B 90 Human Papillomavirus (HPV) 92 Influenza (Flu) 93 Measles, Mumps, and Rubella (MMR) 95 Measles, Mumps, Rubella, and Varicella (MMRV) 97 Meningococcal Vaccines 97 Pneumococcal Vaccines 98 For adults 99 For children 100 Rotavirus 101 Shingles (Herpes Zoster) 102 Chapter 7: What to Expect When You’re Vaccinating 105 Understanding Side Effects: What May Cause Them and What Happens 106 Looking at common vaccine ingredients 106 Distinguishing vaccine delivery methods 110 Watching for localized skin reactions 111 Expecting a systemic immune response 114 Recognizing and Treating Serious Reactions 116 Avoiding allergic reactions 117 Anaphylactic reactions 117 Febrile seizures after childhood vaccinations 118 Guillain-Barré syndrome 119 Thrombocytopenia 120 Looking at Multiple Vaccines and the Immune System 120 Part 3: Scheduling Safety 123 Chapter 8: Vaccines for Children 125 Understanding Mom-to-Baby Immunity 125 Breastfeeding benefits 126 Antibodies passed on during pregnancy 126 Getting a Reminder of the Effectiveness and Importance of Vaccinations 127 Focusing on Vaccinations in the First Year of Life 127 Hepatitis B 128 Rotavirus 129 DTaP (Diphtheria, tetanus, pertussis) 131 Hib 132 IPV (inactivated polio vaccine) 132 Influenza 133 PCV13 134 Knowing New Vaccinations for Toddlers 134 MMR (measles, mumps, rubella) 136 Varicella or MMRV 139 Hepatitis A 140 Surveying a Few Vaccines for Ages 4 to 6 140 Adding Some School-Age Vaccinations 141 Human papillomavirus (HPV) 141 Meningococcal conjugate (MenACWY) 142 Tetanus, diphtheria, and pertussis (Tdap) 142 Needing a Booster: Vaccines for Teens 143 Catching Up on Childhood Vaccines 144 Spreading vaccines out 144 Starting vaccines late 144 Adopting a child from another country 145 Checking Out Vaccine Schedules Around the World 146 Chapter 9: Vaccines for Adults 147 Vaccines When You’re 19–26 Years Old 147 Your yearly flu shot 148 The COVID-19 vaccine 149 A Tdap or Td booster 150 Vaccines When You’re 27–49 Years Old 151 Vaccines When You’re 50–64 Years Old 151 Vaccines When You’re 65-Plus Years Old 153 Influenza 153 Tdap 155 Pneumococcal vaccines 156 Vaccines Before and During Pregnancy 156 Vaccines for Travelers 157 Making sure you’re up to date on routine vaccines 158 Getting other vaccines depending on your destination 158 Catching Up: If Your Parents/Guardians Didn’t Vaccinate You 160 Chapter 10: Spelling Out Who May Face Risks 161 Knowing When to Avoid or Limit Vaccines 161 Considering vaccines and cancer 162 Vaccines and immune disorders 163 Vaccines after organ transplantation 164 Understanding Vaccines and Allergies 165 Allergies to vaccine ingredients and components 165 Different types of reactions 168 Recognizing reactions that actually aren’t allergies 169 Taking precautions before vaccination 169 Assessing Reactions to the COVID-19 Vaccine 170 Rare cases of anaphylaxis 170 Other types of reactions 170 Inspecting ingredients found in current COVID-19 vaccines 171 Getting the COVID-19 vaccine after you’ve had COVID-19 173 Chapter 11: Anti-Vaxxers and Debunking Myths About Vaccines 175 Studying the Rise of Vaccine Hesitancy 176 Understanding why some people don’t vaccinate 176 Looking at the early anti-vaxxers 178 Debunking Common Vaccine Myths 179 Myth: Diseases were disappearing before vaccines were invented 180 Myth: Vaccines cause serious side effects, illnesses, and death 180 Myth: Kids don’t need to be vaccinated so young 181 Myth: Kids don’t need to be vaccinated when illnesses don’t exist in their country 184 Myth: Giving multiple vaccines at the same time overloads the immune system 184 Myth: Vaccines can cause the disease they are supposed to prevent 185 Myth: Not getting vaccinated affects only me 186 Myth: Natural immunity is always best 186 Myth: The MMR vaccine causes autism 187 Myth: Vaccines contain harmful chemicals 188 Reviewing Vaccine Recalls 189 Part 4: The Part of Tens 191 Chapter 12: Five People Who Created Ten (Or More) Modern Vaccines 193 Edward Jenner: Snuffing Out Smallpox 193 Louis Pasteur: Ridding the World of Rabies 194 Jonas Salk and Albert Sabin: Putting Polio Behind Us 195 Maurice Hilleman: The Master of Modern Vaccines 196 Chapter 13: Ten Diseases Without Vaccines, from A to Z 199 Avian Influenzas (Bird Flu) 200 Cytomegalovirus (CMV) 200 Epstein-Barr Virus (EBV) 201 Hepatitis C 202 Herpes Simplex Virus (HSV) 1 and 2 203 HIV/AIDS 204 Lyme Disease 205 Respiratory Syncytial Virus (RSV) 207 West Nile Virus 208 Zika Virus 209 Chapter 14: The Ten Most Lethal Major Pandemics 211 Antonine Plague (165–180) 212 Plague of Justinian (541–750) 212 Bubonic Plague (Black Death) (1346–1353) 213 Cholera (1846–1860) 214 Third Plague Pandemic (1855–1960) 215 Influenza (Russian Flu) (1889–1890) 215 Influenza (Spanish Flu) (1918–1919) 216 Influenza (Asian Flu) (1957–1958) 217 Human Immunodeficiency Virus (HIV) (1981–Present) 217 COVID-19 (2020–Present) 218 Chapter 15: Ten Ways to Boost Your Immune System 219 Getting Your Vaccinations 219 Decreasing Stress 220 Eating Well 220 Maintaining a Healthy Weight 221 Getting Enough Sleep 221 Exercising for Immunity 222 Saying No to Smoking 222 Drinking Only in Moderation 223 Staying Connected 223 Considering Supplements 224 Index 225

    15 in stock

    £15.29

  • Nanovaccinology as Targeted Therapeutics

    John Wiley & Sons Inc Nanovaccinology as Targeted Therapeutics

    1 in stock

    Book SynopsisNANOVACCINOLOGY AS TARGETED THERAPEUTICS The book presents the early-stage development of nanovaccines that could well be the new generation of vaccines which have a great potential for the prevention and treatment of many diseases. Nanovaccinology as Targeted Therapeutics explores recent breakthroughs in the exciting new field of micro- and nanofabricated engineered nanomaterials. In addition to spectroscopic characterizations, significant topics for interdisciplinary research, especially in the fields of nanogels, which deal with polymer chemistry, nanotechnology, materials science, pharmaceuticals, and medicine are explored, where their small dimensions prove highly advantageous. Nanovaccinology could potentially revolutionize conventional therapy and diagnostic methods due to its superior effectiveness over its macro-sized counterparts in almost all biomedical areas. Strong interest in this novel class of material has driven many studies to discover biogenic production methods andTable of ContentsPreface xv 1 Nanotechnology in Vaccine Development and Constraints 1 Tahmina Foyez and Abu Bin Imran 1.1 Introduction 2 1.2 Nanoparticles, an Alternative Approach to Conventional Vaccines 4 1.3 Nanoparticles as Vaccine Delivery Vehicle 5 1.4 Nanotechnology to Tackle the Challenges of Vaccine Delivery 6 1.4.1 Polymeric Nanoparticles 6 1.4.2 Inorganic Nanoparticles 7 1.4.3 Biomolecular Nanoparticles 8 1.4.4 Liposome 9 1.4.5 Virus-Like Particles 9 1.4.6 Micelles 9 1.4.7 Immunostimulating Complexes 10 1.4.8 Self-Assembled Proteins (SAPNs) 10 1.4.9 Emulsions 11 1.5 Constraints and Challenges of Nanovaccines 11 1.6 Concluding Remarks 12 Acknowledgments 13 References 13 2 Nanomedicine and Nanovaccinology Tools in Targeted Drug Delivery 21 Bogala Mallikharjuna Reddy 2.1 Introduction 21 2.2 Nanomaterial-Based Drug Delivery Tools 25 2.2.1 Inorganic Nanoparticles 26 2.2.2 Polymeric Nanoparticles 26 2.2.3 Dendrimers 27 2.2.4 Liposomes 28 2.2.5 Micelles 29 2.2.6 Emulsions 30 2.2.7 Carbon-Based Nanomaterials 30 2.2.8 Self-Assembled Proteins 31 2.2.9 Immunostimulating Complexes 32 2.2.10 Virus-Like Particles 33 2.3 Targeted Drug Delivery Applications 33 2.3.1 Cancer 36 2.3.2 Neurology 37 2.3.3 Cardiology 38 2.3.4 Ophthalmology 38 2.3.5 Pulmonology 39 2.3.6 Tissue Engineering 40 2.3.7 Viral Infections 40 2.3.8 Other Miscellaneous Types 41 2.4 Commercial Nanodelivery Tools 42 2.4.1 Industrial Manufacturing 42 2.4.2 Advantages and Disadvantages 44 2.4.3 Risks and Challenges 45 2.5 Conclusions and Future Prospects 46 Acknowledgments 47 References 47 3 Nanovaccinology and Superbugs 53 Sandhya Kalathilparambil Santhosh, Kaviya Parampath Kootery, Mridul Umesh, Preethi Mariam Alex, Meghna Mani, Adina Roy and Suma Sarojini 3.1 Introduction 54 3.2 Need for Nanovaccines 55 3.3 Types of Nanovaccines 57 3.3.1 Subunit Vaccines 57 3.3.2 Conjugate Vaccines 58 3.3.3 RNA Vaccines 58 3.3.4 Reverse Vaccinology 59 3.3.5 Biomimetic Nanovaccines 60 3.3.5.1 Biomimetic Membranes 60 3.3.5.2 Outer Membrane Vesicle Nanoparticles 61 3.3.6 Nanotoxoids 62 3.3.7 Liposomes 63 3.3.8 Polymeric Nanoparticles 63 3.3.9 Virus-Like Particle 64 3.3.10 Inorganic Nanoparticles 65 3.4 Mechanism of Action of Nanovaccines 65 3.5 Limitations of Nanovaccines 68 3.6 Conclusion 69 Acknowledgment 69 References 69 4 Current Research Trends on SARS-CoV2 Virus Against Nanovaccine Formulation 77 Pushpalatha C., Chhaya Kumar, Sowmya S.V., Dominic Augustine, Elizabeth Abbu Varghese and Jithya Suresh 4.1 Introduction 78 4.2 COVID-19/SARS-CoV2 Pathophysiology 78 4.3 Development of Nanovaccines Against SARS-CoV 2 79 4.4 Biomimetic Nanovaccines Against SARS-CoV 2 80 4.4.1 Virus-Like Particles 84 4.4.2 Nucleic Acids Vaccines 85 4.4.3 Protein Vaccines 86 4.5 Translatable Subunit Nanovaccine Against SARS-CoV 2 86 4.6 Separable Microneedle Patch Nanovaccine 86 4.7 Polymer-Based Nanovaccines 87 4.8 Pharmaceutical Challenges of SARS-CoV2 Nanovaccines 88 4.9 Future Prospects of SARS-CoV2 Nanovaccines 89 4.10 Challenges and Limitations 89 4.11 Conclusion and Outlook 91 References 91 5 Nanovaccinology Against Infectious Disease 95 S. Chakroborty and P. Panda 5.1 Introduction 96 5.2 Nanovaccinology Against Bacterial Disease 97 5.3 Nanovaccinology Against Viral Disease 99 5.4 Nanovaccinology Against Cancer 101 5.5 Nanovaccinology Against Parasite-Born Disease 108 5.6 Nanovaccinology Against Autoimmune Disorders 109 5.7 Conclusion and Outlook 110 Acknowledgments 110 References 110 6 Preclinical and Commercial Trials of Cancer Diagnosis via Nano-Imaging and Nanovaccinology 115 Sowmya S.V., Pushpalatha C., Dominic Augustine, Sibikar P., Bharkhavy K.V. and Elizabeth Abbu Varghese 6.1 Introduction 116 6.2 Role of Nano-Imaging in Cancer Diagnosis, Progression, and Treatment 117 6.2.1 Gold Nanoparticles 117 6.2.2 Quantum Dots 118 6.2.3 Carbon Nanotubes 118 6.2.4 Nanowires 118 6.2.5 Cantilevers and Nanopores 118 6.2.6 Other Types of Nanoparticles 118 6.3 Challenges in the Translation of Nanotechnology-Based Imaging Methods Into Clinical Application 119 6.4 Nanovaccines for Cancer Immunotherapy 119 6.4.1 Composition of Nanovaccines in Cancer Therapy 120 6.4.1.1 Antigens 120 6.4.1.2 Immunostimulatory Adjuvants 121 6.4.1.3 Nanocarriers 121 6.5 Functionalities of Nanocarriers for the Delivery of Cancer Vaccines 122 6.5.1 Efficient Delivery of Vaccines by Nanocarriers 123 6.5.2 Co-Delivery of Antigens and Adjuvants via Nanocarriers 123 6.5.3 Nanocarriers Potentiate Immunomodulation Through Multivalent Antigens and/or Adjuvants 123 6.5.4 Self-Adjuvanted Nanocarriers 123 6.6 Nanovaccine Strategies in Cancer 123 6.6.1 STING Agonist-Based Nanovaccines 124 6.6.2 Neoantigen Nanovaccines 124 6.6.3 mRNA-Based Nanovaccines 124 6.6.4 aAPCs 124 6.6.5 Nanovaccines for Combination Therapy 124 6.7 Preclinical and Clinical Trials of Applications of Nanoimaging and Nanovaccinology in Cancer 125 6.8 Recent Developments in the Trials of Nanovaccinology in Cancer 126 6.9 Perspectives and Future Directions 127 6.10 Conclusions 127 References 127 7 Biomedical and Electronic Tune-Ups of 2C4NA Nanocrystalline Sample 131 Maalmarugan J., Egbert Selwin Rose A., Anbarasan P., Poorani R., Aarthi N., Ganesan H., Senthil Kannan K. and Flora G. 7.1 Introduction 132 7.2 Computational, Tribological, Fluorescence, and Influx Study 133 7.3 Antidiabetic (AD) Study, Anticancer Study, and Anti-Inflammatory Study 138 7.4 Conclusion 139 References 139 8 Biological, Electronic-Filter, Influx and Theoretical Practicalities of 2-Chloro-6-Nitroaniline (2C6NA) Crystals for Biomedical and Microelectronics Tasks 145 Maria Sumathi B., Maalmarugan J., Ganesan H., Saravanan P., Patel R.P., Sheeba M., Flora G. and Senthil Kannan K. 8.1 Introduction 146 8.2 Computational and Influx 146 8.3 Antibacterial, Antifungal, Antidiabetic, DPPH, FRAP, Anticancer 148 8.4 Conclusion 150 References 151 9 Antidiabetic, Anti-Oxidant, Computational, Filter, and Tribological Characterizations of Bis Glycine Lithium Bromide Monohydrate Nano (32 nm) Scaled Crystals 157 Dayana Lobo F., Senthil Kannan K., Mathivanan V., Jacintha Tamil Malar A., Christy S., Flora G., Ganesan H. and Maalmarugan J. 9.1 Introduction 158 9.2 Experimental 158 9.2.1 Synthesis 158 9.3 Results and Discussions 159 9.3.1 Single Crystalline XRD (SXRD) Study and Powder XRD (PXRD) Studies 159 9.3.2 Fluorescence (FL) Study for 32-nm Scale 160 9.3.3 Antidiabetic (AD) Study and Influx Study 160 9.3.4 AO-DPPH, FRAP of Antioxidant Activity 162 9.3.5 Tribology—Load Capacity by the Compressive Strength Model of the Polymeric Bearings, Software-Based Thermal Ellipsoidal Plot 162 9.4 Conclusion 164 References 164 10 Device Utility, Energy, and Bioutility of N2MNM4MBH Macro, Nano Models 169 Pauline Jenifer S., Flora G., Zozimus Divya Lobo C., Charles A., Senthil Kannan K., Anbuvel D., Prajith V. and Jemma Hermelin Jesy Diaz 10.1 Introduction 170 10.2 Synthesis and XRD 171 10.3 Influx 171 10.4 Computational 171 10.4.1 Antidiabetic Study 171 10.5 Conclusion 177 References 177 11 Biocurative, Tribological, Electro-Functionalities of ZnO-MIZN Nanoparticles 183 Senthil Kannan K., Prabhjeet Kaur Dhillon, Jemma Hermelin Jesy Diaz, Padmavathi P., Flora G., Irudhya Sahaya Lancy S., Jeeva Rani Thangam G. and Sheeba M. 11.1 Introduction 184 11.2 Antibacterial Activity 185 11.3 XRD and Magnetic Effect 186 11.4 Tribological Data for Nano Sample Coatings of ZnO-MIZN 189 11.5 Filter Utility 189 11.6 Conclusion 190 References 190 12 Nanotubular Device Effect, Super Cell Effectiveness, Hirshfeld Energy Analysis and Biomedicinal Efficacy of 2-Fluoro-5-Nitro-Aniline (2F5NA) Crystals 195 Flora G., Munikumari A., Sheeba M., Jemma Hermelin Jesy Diaz, Senthil Kannan K., Ponrathy T., Muthu Sheeba M. and Joshua Steve Abishek B. 12.1 Introduction 196 12.2 XRD and Computational 197 12.3 Bioutility 207 12.3.1 Antibacterial of 2F5NA Crystals 207 12.4 Conclusion 208 References 208 13 Nano, Peptide Link, Pharma Impact and Electron Density of AMPHB Macro, Nano Crystalline Samples 213 Senthil Kannan K., Dayana Lobo F., Gayathri A., Prathebha K., Jacintha Tamil Malar A., Maria Sumathi B., Flora G. and Egbert Selwin Rose A. 13.1 Introduction 214 13.2 Characterizations 215 13.2.1 XRD and Computational Impactness 215 13.2.2 Antidiabetic (AD), Anti-Inflammatory (AI), and Anti-Fungal (AF) Effect of AMPHB Macro and Nano Crystals 219 13.3 Conclusion 220 References 221 14 Super Lattice, Computational Interactions and Bio-Uses of CPDMDP Crystals 227 Flora G., Christy S., Shobana V., Divya R., Jemma Hermelin Jesy Diaz, Pauline Jenifer S., Senthil Kannan K. and Jacintha Tamil Malar A. 14.1 Introduction 228 14.2 Computational 229 14.3 Synthesis 234 14.4 Xrd 234 14.5 Influx of CPDMDP of Both Scales 235 14.6 Antidiabetic Activity of Macro, Nano CPDMDP Crystals 235 14.7 Antioxidant Activity 236 14.8 Conclusion 237 References 237 15 Biological Effect Nanotubular, Vanderwall’s Impact, of 4-Methyl-2-Nitroaniline (4M2NA) Nanocrystals 243 Senthil Kannan K., Pauline Jenifer S., Divya R., Raju K., Gayathri A., Jemma Hermelin Jesy Diaz, Maria Sumathi B. and Flora G. 15.1 Introduction 244 15.2 XRD and 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Inside Scanned, you’ll also find: The massive implications of a tech-enabled digital ID, social credit systems and biometric tracking How basic freedoms and privacy are being handed over to the state and private companies without our knowledge or consent How government programmes and increased surveillance will facilitate discrimination, segregation and stigmas for huge segments of the population Few people want to be seen as outliers, especially if it means feeling responsible or being blamed for the suffering and deaths of others. ‘But there is a fundamental flaw in applying the “greater good” argument to vaccine passports,’ Corbishley writes, ‘because the passports themselves offer precious little in the way of potential good – and a huge amount in the way of potential harm.’ This is not a liberal or conservative debate. This is not a vaccinated or unvaccinated debate. This is about freedom, global democracy and how much we are willing to give up. 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McCullough, MD, MPH; chief medical advisor, Truth for Health Foundation“Scanned by Nick Corbishley is essential reading; this book explains in an incontrovertible way how ‘vaccine passports’ have already closed off basic human liberties in many parts of the formerly free world, and shines a light on the mounting layers of dystopia and control for which they form the foundation. No one should risk missing the information in this book.”—Naomi Wolf, New York Times best-selling author of The End of America and Outrages“‘Show me your papers’ is a phrase that should send chills down the spine of any thinking person. The idea that we would bar free citizens from access to public life because they have chosen to say, ‘No, thank you’ to a pharmaceutical intervention for religious, medical, or philosophical reasons is breathtakingly wrong. Nick Corbishley’s outstanding new book, Scanned, explains why. 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