Surgery Books

Book SynopsisPart travelogue, part autobiography, part medical mystery, this moving book by the poet laureate of medicine (The New York Times) and bestselling author of Awakenings takes us to a tiny Pacific atoll and the island of Guam to explore the genesis of disease, the wonders of botany, and the complexities of being human.Sacks's total immersion in island life makes this luminous, beautifully written report a wonderous voyage of discovery. As a travel writer, Sacks ranks with Paul Theroux and Bruce Chatwin. As an investigator of the mind's mysteries, he is in a class by himself. —Publishers WeeklyFor Oliver Sacks, islands conjure up equally the romance of Melville and Stevenson, the adventure of Magellan and Cook, and the scientific wonder of Darwin and Wallace.Drawn to the tiny Pacific atoll of Pingelap by intriguing reports of an isolated community of islanders born totally color-blind, Sacks finds himself setting up a

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Book SynopsisThis book acquaints the clinicians with the most frequent problems that may occur after kidney transplantation. It deals with the most worrying extra-renal complications that may affect the kidney transplant recipient, namely infection, cardiovascular disease and malignancy.Table of Contents1. Man's Universe of Symbols 2. Human Values in a Changing World 3. Comments on Aggression 4. Systems Perspectives on the Problem of Mental Illness 5. A Definition of the Symbol 6. An Etymology of Symbolism 7. The Evolutionary Origins of Symbolism 8. The Mind-Body Problem: A New View 9. General Theory of Systems: Application to Psychology 10. Toward a Generalized Theoretical Model for Psychology 11. Problems of Education in America 12. On Interdisciplinary Study

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Book SynopsisThere is a great need for a visual resource to document, with clarity, the possible outcomes of surgery, including side effects and complications, and how these outcomes vary from individual to individual. Using a straightforward approach, Outcomes of Skin Surgery: A Concise Visual Aid is an easy-to-consult and highly illustrated reference for surgeons and patients alike. This text takes a major step forward in establishing a realistic basis for the decision-making process during a consultation.Procedures highlighted in the text include: the excision of benign and malignant tumors diagnostic biopsies cryosurgery curettage for superficial lesions photodynamic therapy Table of Contents1. No treatment. 2. Curettage, cautery, snip, shave, trichloroacetic acid. 3. Cryosurgery. 4. Radiotherapy. 5. Biopsies and excisions. 6. Flaps. 7. Grafts 8. Special sites: ear. 9. Special sites: nose. 10. Special sites: lip. 11. Special sites: eye. 12. Special sites: nails. 13. Open wound healing. 14. Wound dressings. 15. Topical therapies.

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Book SynopsisAs an active surgeon and former department chairman, Dr Paul A Ruggieri has seen the good, the bad, and the ugly of his profession. This title uncovers the truth about the abusive, exhaustive training and the arduous devotion of his old-school education. It explores the twenty-four-hour challenges that come from patients and their loved ones.

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Book SynopsisThinking about a surgical career? About to start surgical training? Do you know what to expect and how to thrive? The Hands-on Guide to Surgical Training is the ultimate, practical guide for medical students and junior doctors thinking about taking the plunge into surgery, and also for surgical trainees already in training. It's full of invaluable, practical information and career guidance to ensure you get the most out of your surgical career. It offers general guidance and advice on surgical training, together with detailed information on each of the nine surgical subspecialties, each written by seniors and consultants, as you make both clinical and career-based choices. Undoubtedly one of the most comprehensive resources for surgical trainees available, The Hands-on Guide to Surgical Training will be essential reading throughout your training and surgical career. Take the stress out of surgical training with The HTrade ReviewFor those considering surgical training, or for those already progressing through this, “The Hands-on Guide to Surgical Training” is a very readable 304-page guide to the nitty-gritty key points no-one ever tells you about. Comprehensive in its coverage, the text starts with an introduction to the clinical side of surgery. Career structure, surgical equipment and sutures (with colour pictures) together with useful advice on theatre etiquette all offer an excellent introduction to those new to the operating theatre environment. The three most frequently encountered operations are reviewed, including operative photographs, and a guide to ward rounds and clinics provides a wealth of practical experience about what to do and when. The non-clinical chapters explain the different stages of training prior to entering core surgery, and each surgical specialty is then addressed in-depth including recruitment, exams and a trainee eye-view of what it is like to work in the specialty. What really makes this book stand out is the useful training information that all trainees want to know, but which is usually hard to come by and impossible to find in one place. Competition ratios for different surgical specialties, specific career advice for women in surgery, an overview of the training bodies overseeing surgery, the European Working Time Directive and pay-banding all stand out as very pertinent areas trainees should know about, but which are rarely often covered in similar textbooks. The pocket-size format of this book is perfect for carrying around at work and the text contains bold highlights to pick out the useful sections, although in some chapters this is perhaps a little over-done. Overall, this book comes highly recommended as a unique resource that manages to combine key practical clinical information with the really useful sort of training information that many will be keen to read. (Ed Fitzgerald MRCS, Specialist Registrar, General Surgery, The Royal Marsden Hospital, London)Table of ContentsPreface vi Introduction vii Contributors ix So you want to be a surgeon? xi Abbreviations xvii Clinical 1 Theatres 1 Surgical instruments 1 Sutures 10 Theatre etiquette 12 Patient safety and the WHO surgical checklist 17 How to write the operation note 22 Introduction to operative sections 26 Appendicectomy 26 Inguinal hernia repair 31 Dynamic hip screw 37 2 Wards 45 3 Clinics 71 4 On Call 78 Non-clinical Generic stage 5 The Foundation Years 89 6 The Core Training Years 100 7 The Specialty Training Years 122 Surgical specialties 8 General Surgery 140 9 Urology 148 10 Cardiothoracic Surgery 156 11 Oral and maxillofacial surgery 160 12 Ear, nose and throat surgery (Otorhinolaryngology – head and neck surgery) 166 13 Paediatric surgery 171 14 Neurosurgery 179 15 Orthopaedics 186 16 Plastic Surgery 193 Other issues 17 Applying for Jobs 201 18 Flexible Training and Women in Surgery 219 19 Academic Surgery 225 20 Other Issues in Surgical Training 233 21 Fellowships 250 22 Approaching Consultancy 256 Appendix 1: Preoperative assessment 264 Appendix 2: Consent 286 Appendix 3: Local Anaesthetics 292 Index 295

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Book SynopsisWhat do you need to do before sitting the written component of the FRCS (Tr and Orth) examination? Practice, practice, practice. Sadly the MCQs and EMQs in the actual examination are not this straightforward. This book will help the orthopaedic surgeon preparing for the written part of the examination to be ready to face the task ahead. The MCQs and EMQs appear in the same format as the examination and cover the syllabus topics. Divided into subspecialty chapters, including trauma and basic science, this book is ideal for use alongside a revision plan. The questions have detailed answers and selected references, arming readers with the knowledge they need to approach the topic correctly. Written by recent, successful examination candidates, this question-and-answer-based revision guide is ideal preparation for the FRCS (Tr and Orth) examination as well as being helpful for other postgraduate orthopaedic exams.Table of ContentsPreface; Foreword Barry Ferris; 1. Introduction Kesavan Sri-Ram; 2. Hand and wrist Maxim Horwitz and Elliot Sorene; 3. Shoulder and elbow Deborah Higgs and Simon Lambert; 4. Spine Zaher Dannawi and Rajiv Bajekal; 5. Hip and pelvis Nashat Siddiqui and Phil Kerr; 6. Knee Kesavan Sri-Ram and Howard Ware; 7. Foot and ankle Kesavan Sri-Ram and Andrew Robinson; 8. Pathology Danyal Nawabi and Tim Briggs; 9. Paediatric orthopaedics Russell Hawkins and Deborah Eastwood; 10. Trauma Paul Whittingham-Jones, Kesavan Sri-Ram and Dennis Edwards; 11. Basic science Ben Rudge and John Skinner; Index.

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Book SynopsisMedicine and Surgery is an exciting new book that contains the core information needed by medical students in the run up to exams. This is the only book available that covers both medicine and surgery. It encompasses all of the major systems and core subjects Every condition is discussed under the key headings of definition, epidemiology, aetiology, pathophysiology, clinical features, investigations, management and prognosis The content follows a very consistent and familiar style, so that information is easily accessible, digestible and memorable Each chapter opens with an overview of clinical method before discussing the most common conditions relevant to that speciality Medicine and Surgery: A Concise Textbook is written specifically for medical students as essential revision preparation, for junior doctors as a refresher on the wards and for other allied health professionals who want a quick remindTrade Review''I like the way the book goes through each disease using the same system of definition, aetiology etc. This makes it easier to learn….The content is exactly what the undergraduate brain needs” Final year student, University of OxfordTable of Contents1 Principles and Practice of Medicine and Surgery. 2 Cardiovascular System. 3 Respiratory System. 4 Gastrointestinal System. 5 Hepatic, Biliary & Pancreatic Systems. 6 Genitourinary Systems. 7 Nervous System. 8 Musculoskeletal System. 9Dermatology & Soft Tissues. 10 Breast Disorders. 11Endocrine System. 12 Haematological System. 13 Nutritional and Metabolic Disorders. 14 Genetic Syndromes. 15 Overdose, Poisoning and Addictions. Index

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Book SynopsisA pioneering organ transplant surgeon narrates in gripping detail the revolutions that have transformed modern surgery, and the turmoil in medical education and health care reform as new capacities to prolong life and restore health run headlong into unsustainable costs. Tilney’s stage is the famous Boston teaching hospital, Brigham and Women's.Trade ReviewDr. Tilney has an eye for fascinating details, shocking stories, and unexpected connections. Invasion of the Body is a riveting account of the astonishing transformation of surgery over the past century. -- Atul Gawande, M.D.With the history of surgery and the surgical profession as his main subjects, Tilney does not hesitate to take readers on numerous side trips that enhance their understanding of the field and illustrate the interrelatedness among the discipline of surgery and the rest of medicine. Touching on everything from sanitation-free barber surgeons to robotics, he discusses the evolving science of surgery, the growth of the profession, the individuals responsible for incremental developments and breakthroughs, the technologies now available, and the directions in which the field might be headed...A very readable book that should prove fascinating to both lay readers and professionals. -- Dick Maxwell * Library Journal *Always entertaining...Dr. Tilney's analysis of surgical developments during his long career--he graduated from medical school in 1962--is little short of brilliant...Dr. Tilney provides full accounts of both the science and practice of cardiac and transplant surgery, with their backgrounds in basic immunology and the technology of the heart-lung machine. He illustrates his narrative with vivid examples of real operations, including some from his own surgical experience...He has a wonderful capacity to describe what surgeons actually do when they are operating, why they do it and why it sometimes ends in failure...Dr. Tilney is concerned, as every American citizen ought to be, with the chaotic state of American health care. His last chapter contains a great deal of wisdom (and documentation) about the problems of spiraling costs, inequality of access and the pernicious ways in which the market drives decisions about how much and what kind of treatment a patient receives...He has made a shrewd diagnosis of the lack of system in American health care, and politicians would do well to take his critique seriously. -- William Bynum * Wall Street Journal *Tumours removed, joints replaced, organs transplanted: every weekday, 85,000 non-emergency operations take place in the United States alone. Distinguished U.S. surgeon Nicholas L. Tilney intersperses moments from his own career with a rousing history of the evolution of surgery, breakthrough by breakthrough--from near-butchery to today's fine-tuned procedures. Wading through the gore with aplomb, he covers anaesthesia, pharmaceuticals, asepsis, health-care reform, surgery in war and in peace, facial transplants and more. * Nature *Readers will come away with a new appreciation of the scalpel-wielding specialists who have paved the way for heart and organ transplants, cancer removal, and plastic surgery. -- Laura Landro * Wall Street Journal *

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Book SynopsisAn estimated 30,000 children are born in the USA with congenital heart disease each year, two thirds of which will require corrective surgery. Medical advances have formed a trend of operating on newborns rather than waiting until the child is older. Ten years ago, the mortality for these operationswas 60% to 70%. That percentage has dropped to 2%. This specialized book explores the basic mechanisms of neurologic injury associated with congenital heart surgery while covering the emerging technologies for assessment of neurologic integrity and injury. The text also highlights the current and future techniques for reducing and preventing these injuries, and reviews the pertinent medicolegal issues.Trade ReviewI found this book very interesting and informative. I recommend this book to END technologist who monitor pediatric cardiac patients and who would like to better understand the mechanisms of brain injury to the patient population during surgery... The book raises many questions and provides a great resource for determining what additional studies are required to ensure the most positive post-surgical outcomes. American Journal of Electroneurodiagnostic TechnolTable of ContentsPART I DEVELOPMENT OF THE CENTRAL NERVOUS SYSTEM: Brain Development and its Relationship to PAtterns of Injury Maturation of Brain ATP Metabolism EEG Maturation with Special Reference to Epiletogenic Effects of Hypoxia Programmed Cell Death The Biology of Cell Death in the Nematode Caenorhabditid elegans and Implications for the Understanding and Treatment of Human Brain Injury after Cardiac Surgery. PART II ASSESSMENT OF CNS FUNCTION: The Neurological Examination Cognitive and Psychomotor Developmental Assessment EEG Methods with PArticular Reference to Neonatal Seizures Transcranial Doppler Technology: The Noninvasive Monitoring of Cerebral Perfusion During Cardiopulmonary Bypass PET and SPECT in the Assessment of Cerebral Function Brain Monitoring Using Optical Imaging and Optical Spectroscopy Assessment of CNS Function: Cerebral Blood Flow and Metabolism Cerebral Evaluation with Nuclear Magnetic Resonance Spectroscopy. PART III MECHANISMS OF NEUROLOGICAL INJURY: Mechanisms of Perinatal Ischemic Brain Damage Endothelial and White Cell Activation in Bypass and Reperfusion Injury: Brain Injury Excitotoxicity and Nitric Oxide. PART IV CLINICAL AND LABORATORY STUDIES OF CARDIOPULMONARY BYPASS, HYPOTHERMIA AND CIRCULATORY ARREST: A Newborn Canine Model of Hypothermic Circulatory Arrest Effects on CPB, Hypothermia and Circulatory Arrests on Cerebral Blood Flow and Metabolism Assessment by NMRS of the Effects of Cardiopulmonary Bypass, Hypothermia and Circulatory Arrest pH MANAGEMENT During Hypothermic Cardiopulmonary Bypass with Circulatory Arrest. PART V A PROSPECTIVE CLINICAL STUDY OF CIRCULATORY ARREST AT CHILDREN'S HOSPITAL, BOSTON: Methods and Procedures EEG Findings Neurologic and MRI Findings

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Book SynopsisPresents more than 800 instruments and tips associated with official names, common nicknames, and descriptions of instrument features, categories, and uses. Common types of clamping, grasping, cutting, and retracting instrumentsTable of Contents1. Instruments, Care of Instruments, and Setup Guidelines 2. General Instruments 3. Laparoscopic Instruments4. Robotic Instruments5. OB-GYN Instruments6. Urology Instruments7. Orthopedic Instruments8. Neurosurgical Instruments9. Vascular, Thoracic, and Cardiac Instruments10. Ear, Nose, and Throat Instruments11. Dental and Maxillofacial Instruments12. Ophthalmic Instruments13. Plastic Surgery InstrumentsAppendix: Answer Key to Surgical Session Questions and Labeling Exercises

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Book SynopsisIt wasn’t supposed to be this hard. If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting fifty years of false starts, abysmal failures and miraculous triumphs, as experienced by one the world’s foremost heart surgeons, O.H. “Bud” Frazier, who has given his life to saving the un-savable.  His journey takes him from a small town in west Texas to one of the country’s most prestigious medical institutions, The Texas Heart Institute, from the halls of Congress to the animal laboratories where calves are fitted

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Book SynopsisThe eighth edition of the acclaimed text Operative Pediatric Surgery continues to provide a unique level of comprehensive detail on the full range of surgically treatable conditions presented in neonate and childhood as well as in utero. Written by expert international authors, all chapters cover both minimal access and open surgery, with operative techniques illustrated by both high-quality colour line artwork, operative photographs, and a library of video clips. Encompassing the full range of pediatric surgery operations that both trainee and experienced pediatric surgeons require, this established operative guide is the standard reference for the pediatric surgeon and will ensure that they can access the most up to date and authoritative information to benefit their clinical practice.â ensures authoritative coverage of all aspects of pediatric surgeryâincludes the latest operative techniquesâreviews alternative surgical approachesâaids viTable of ContentsVideos. Preface. List of abbreviations used. Acknowledgments. Contributors. Vascular access. HEAD AND NECK. Head and neck surgery. Tracheostomy. ENDOSCOPY. Bronchoscopy. Esophageal dilatation. Esophagogastroduodenoscopy and endoscopic retrograde cholangiopancreatography. Colonoscopy. THORACIC. Principles of thoracic surgery. Esophageal atresia: Open and thoracoscopic approaches. Esophageal replacement with colon. Esophageal replacement with transposition of the stomach. Esophageal replacement with jejunal interposition. Congenital diaphragmatic hernia. Extracorporeal membrane oxygenation. Eventration of the diaphragm. Principles of lung surgery. Empyema. Chylothorax. Mediastinal masses. Chest wall deformities. Patent ductus arteriosus. Thoracoscopic sympathectomy. Thymectomy. ABDOMINAL. Inguinal hernia, hydrocele, and other hernias of the abdominal wall. Exomphalos/omphalocele. Gastroschisis. Abdominal surgery: General principles of access. Fundoplication. Total esophagogastric dissociation. Achalasia. Gastrostomy. Pyloromyotomy. Bariatric surgery. Duodenal atresia and stenosis. Malrotation. Congenital atresia and stenosis of the intestine. Meconium ileus. Vitellointestinal (omphalomesenteric) duct anomalies. Duplications of the alimentary tract. Intussusception. Appendectomy. Necrotizing enterocolitis. Anorectal malformation. Cloaca. Laparoscopic surgery and imaging-directed surgery for anorectal malformation. The Malone antegrade continence enema. Hirschsprung disease. Inflammatory bowel disease. Rectal polyps. Acquired anorectal disorders: Prolapse, fistula, and hemorrhoids. Colostomy formation and closure. Surgery of short bowel syndrome: Longitudinal intestinal lengthening and tailoring and serial transverse enteroplasty. Surgery of portal hypertension. Cholecystectomy. Surgery for biliary atresia: Open and laparoscopic. Choledochal malformation. Splenectomy. TUMORS. Liver resection. Wilms’ tumor. Neuroblastoma. Rhabdomyosarcoma. Sacrococcygeal teratoma. ENDOCRINE. Thyroidectomy. Pancreatectomy for hyperinsulinism. Adrenalectomy. UROLOGY AND GYNECOLOGY. Cystourethroscopy. Ureteropelvic junction obstruction. Nephrectomy and partial nephrectomy. Vesicoureteric reflux: Open and minimally invasive treatment. Ureteric duplication. Urinary diversion. Renal calculi. Posterior urethral valves. Hypospadias. Orchidopexy. Testicular torsion. Circumcision, meatotomy, meatoplasty, and preputioplasty. Varicocele. Bladder exstrophy and epispadias. Surgical treatment of disorders of sexual development. Ovarian cyst and tumors. TRAUMA. Burns and burn surgery. Thoracic trauma. Abdominal trauma. SPECIAL SECTION. Vascular anomalies. Fetal surgery. Kidney transplantation. Liver transplantation. Intestinal transplantation. Interventional radiology. Exposure for spinal surgery. Surgery of conjoined twins. Index.

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Book SynopsisSubstantially revised to reflect the most recent surgical techniques and practices, this reference describes the most effective strategies to prevent, identify, and manage complications in vascular surgery-guiding surgeons through patient selection; instances of entrapment, malpositioning, and rupture; emerging endovascular treatments; and specific device-related complications.Trade Review"…an indispensable book that is excellently written, well edited, and comprehensive."-Journal of Vascular SurgeryTable of ContentsPitfalls of Noninvasive Vascular Testing Dennis F. Bandyk Cardiopulmonary Complications Related to Vascular Surgery W. Darrin Clouse and David C. Brewster Renal Failure and Fluid Shifts Following Vascular Surgery Gregory J. Cherr and Kimberly J. Hansen Intimal Hyperplasia: The Mechanisms and Treatment of the Response to Arterial Injury Michael J. Englesbe and Alexander W. Clowes The Healing Characteristics, Durability, and Long-Term Complications of Vascular Prostheses Glenn C. Hunter and David A. Bull Anastomatic Aneurysyms Gary M. Jacobs and Alexander D. Shepard Hypercoaguable States and Unexplained Vascular Graft Thrombosis Jonathan B. Towne Complications and Failures of Anticoagulant and Antithrombotic Therapy John R. Hoch Gastrointestinal and Visceral Ischemic Complications of Aortic Reconstruction Daniel J. Reddy and Hector Dourron Spinal Cord Ischemia Alfio Carroccio, Nicholas J. Morrissey, and Larry H. Hollier Impotence Following Aortic Surgery Richard Kempczinski Complications Following Reconstructions of the Pararenal Aorta and Its Branches Kenneth J. Cherry Complications of Modern Renal Revascularization Jeffery D. Cardneau and Louis M. Messina The Diagnosis and Management of Aortic Bifurcation Graft Limb Occlusions Mark T. Eginton and Robert A. Cambria Problems Related to Extra-Anatomic Bypass Including Axillofemoral, Femorofemoral, Obturator, and Thoracofemoral Bypasses Kyle Mueller and William H. Pearce

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Book SynopsisThis resource stands as the only authoritative text to specifically focus on developments and best practices in anesthesiology for procedures affecting the gastrointestinal tract and related appendages. This book provides in-depth coverage of topics such as risk assessment, stress response, and scoring, as well as spans anesthetic trends and practices for endoscopic and laparoscopic procedures, as well as a variety of invasive procedures including hepatobiliary, pancreatic, colorectal, colonic, and abdominal surgeries.Trade Review"…we have long needed…an authoritative text devoted to these areas of practice and now we have it….I am particularly pleased to see whole chapters devoted to preassessment, preoptimization and perioperative fluid management, all crucial areas and ones which are sadly often inadequately considered…."…I can see this book being a valuable addition to the library of any anaesthetist who regularly works with a gastrointestinal surgeon. Not only that, but it will also be of value to non-medical anaesthetists, theatre practitioners, nurses and even surgeons. I am honoured to have been asked to be a (very small) part of it."-Professor Brian J. Pollard, Professor of Anaesthesia, The University of Manchester, United Kingdom, and Honorary Consultant in Anaesthesia and Critical Care, Central Manchester and Manchester Children's University Hospitals NHS Trust,Manchester, United KingdomTable of ContentsPhysiology of the Gastrointestinal Tract (Including Splanchnic Blood Flow and Tonometry). Surgical Considerations in Upper GI Surgery. Surgical Considerations in Lower Gastrointestinal Surgery. Stress Response during Surgery. Measurement and Prediction of Surgical Outcomes. Reducing Morbidity after Colorectal Surgery: Surgical Perspectives. Preoperative Assessment. Perioperative Fluid Management and Optimization. Regional Anaesthesia in Abdominal Surgery. Sedation for Endoscopic Procedures. Anaesthesia for Esophagogastric Surgery. Anaesthetic Considerations for Gastric Surgery. Anaesthesia for Bariatric Surgery. Anaesthesia for Antireflux Surgery. Anaesthesia for Hepatobiliary Surgery. Anaesthesia for Pancreatic Surgery. Anaesthesia for Laparoscopic Surgery. Anaesthesia for The Carcinoid Syndrome. Anaesthesia for Phaeochromocytoma Resection. Anaesthesia for Colorectal Surgery. Anaesthesia for Colorectal Surgery in the Elderly. Rapid Recovery after Major Abdominal Surgery. Anaesthesia for Anorectal Surgery. Anaesthesia for Emergency Exploratory Laparotomy. Postoperative Pain Management after Abdominal Surgery. Postoperative Nausea and Vomiting after Abdominal Surgery. The Role of the Critical Care Unit in Abdominal Surgery.

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Book SynopsisIntended as a practical guide to the treatment of nail problems through medical and surgical means, this book is aimed at the general practitioner, dermatologist and podiatrist. The emphasis throughout is on practical procedures which are in the main relatively simple.Table of ContentsPreface;. 1. Anatomy and Physiology of the Nail Apparatus;. 2. Nail Unit Infections;. 3. Nail Signs and Systemic Disease;. 4. The Nail in Dermatological Diseases;. 5. Occupational Nail Disorders;. 6. Nail Cosmetology;. 7. Nail Unit Tumours and Surgery;. Index

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Book SynopsisTraditionally, vascular disorders of the upper extremity have been slighted in conventional vascular surgery texts, despite the fact that these disorders are among those most frequently encountered. Since its original publication in 1983, this text has been a welcome and effective remedy for this reference gap. The current edition of this widely acclaimed classic, succeeds, once again, in its goal to expertly and comprehensively present the clinical presentation, diagnostic techniques, and therapeutic approaches to almost the full range of common and uncommon conditions affecting this area. In his review of the second edition (Journal of Vascular Surgery, May 1990), Dr. Kenneth Ouriel calls this book well organized, well illustrated, and comprehensive and concludes: Mastery of this text will allow one to diagnose and treat upper extremity vascular problems in a logical and efficient manner, providing the patient with the best opportunity for successful management of these Trade Review"This book should be on the shelf of anyone interested in this area" Journal of Vascular Surgery (review of the second edition) "Within the scope of vascular surgery there is no comparable text. This is an authoritative book that deals exclusively with vascular disorders of the upper extremity. The book provides a single-source text for specific problems that is easy to read and understand. In addition, the textbook provides a thoughtful and studied approach into perplexing problems associated with cumulative trauma disorders and thoracic outlet compression. Thus, this book serves as a ready reference for a variety of physicians including vascular and general surgeons, as well as general internists and vascular medicine specialists. "...highly recommended and well priced." Annals of Vascular Surgery "The 3rd edition of Vascular Disorders of the Upper Extremity is a portable size book that brings the reader up to date. A large majority of upper extremity problems encountered by the practicing vascular surgeon pose difficulties for two reasons: (1) patient volumes outside a referral center are minimal, and (2) the pathophysiology rarely involves atherosclerosis. Therefore, it is important for the practicing vascular surgeon to have a reasonable reference source to deal with these infrequent, but often complicated, cases." Journal of Vascular Surgery "I find this a timely and valuable contribution. In a crowded field of texts on circulatory disease, this focused, well written, beautifully illustrated, and comprehensively referenced work will be a useful addition to the library of clinicians caring for patients with upper extremity disorders." Doody’s Review Service "[Dr. Machleder’s] experience is evident in what he writes, and that translates into well-written, readable chapters. "...this book would be of interest to the vascular surgeon, general surgeon and trainee in surgery. It serves as a useful review of various issues on the management of these often complex vascular problems. It would be a good book to have for most practising physicians who encounter patients with upper extremity vascular disorders." Canadian Journal of SurgeryTable of ContentsPreface. H.I. Machleder. Part I: The Vascular Examination. 1. The Initial Clinical Examination. H.I. Machleder. 2. Noninvasive Vascular Laboratory Assessment. D.S. Sumner. 3. Angiography in the Diagnosis and Management of Vascular Disorders of the Upper Extremity. A.S. Gomes. . Part II: The Cumulative Trauma Disorders. 4. Introduction to Neurovascular Compression Syndromes at the Thoracic Outlet. H.I. Machleder. 5. Neurogenic Thoracic Outlet Compression Syndrome. H.I. Machleder. 6. Electrophysiological Evaluation of Patients with Cervicobrachial Pain Syndromes. S.E. Jordan, H.I. Machleder. 7. Somatosensory Evoked Potentials in the Assessment of Upper Extremity Neurovascular Compression. M.R. Nuwer. 8. Evaluation and Treatment of Repetitive Motion Disorders of the Upper Extremity in Office Workers and Musicians. E.F. Pascarelli. 9. Arterial Compression at the Thoracic Outlet. H.I. Machleder. 10. Venous Compression at the Thoracic Outlet. H.I. Machleder. 11. Surgical Approaches to Primary and Recurrent Thoracic Outlet Compression Syndromes. D.B. Ross. 12. The Management of Neuropathic Pain. J.P. Schwartz, A. Belzberg. . Part III: Intrinsic and Aquired Disorders of the Upper Extremity Vessels. 13. Small Artery Disease of the Upper Extremity. K. Williamson, J.M. Edwards, L.M. Taylor, G.J. Landry, J.M. Porter. 14. The Axillo-Subclavian and Brachial Arteries. H.I. Machleder. 15. Hemangiomas an Vascular Malformation of the Upper Extremity. P.E. Burrows, T. Laor. 16. Complications of Vascular Access in the Upper Extremity. L.L. Powell, S.E. Wilson. . Part IV: Vascular Manifestations Systemic Disorders. 17. Upper Extremity manifestations of Systemic Vascular Disorders. D.J. Klashman, S.C. Ng, D.H. Kono, H.E. Paulus. 18. Current Techniques in Thoracoscopic Sympathectomy. S.S. Ahn, K.M. Ro, J.P. Johnson

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Book SynopsisDeveloped over previous editions by the Royal College of Surgeons in Ireland to support students attending the three RCSI universities, this convenient handbook provides pragmatic guidance to the principles and practice of surgery that students can expect to encounter during undergraduate studies. Spanning the full range of surgical specialties, information is presented in a convenient and clinically relevant format that takes the students through the patient journey from presenting symptoms and aetiology to investigations, management and follow-up. The text, written as easy-to-read and easy-to-remember bullet lists, is supplemented throughout by tables, management algorithms and colour illustrations. Key Features: Concise specifically for the undergraduate medical student by a highly experienced team of surgical educators Accessible bullet text ideal for rapid reference Flexible for use when on the ward and during finals revision<Table of Contents1. Principles of Surgery. 2. Hernias. 3. Upper Gastrointestinal Surgery. 4. Hepatobiliary Surgery. 5. Colorectal Surgery. 6. Inflammatory Bowel Disease. 7. Peripheral Vascular Disease. 8. Breast Disorders. 9. Endocrine Disorders. 10. Urology. 11. Cardiothoracic Surgery. 12. Major Trauma. 13. Plastic Surgery. 14. Orthopaedic Surgery. 15. Neurosurgery. 16. Otorhinolaryngology (ENT).

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Book SynopsisThis robust, dynamic, and international field has grown to include interdisciplinary research, continually improving methodology, and globalization of training. Reflecting the diverse nature of the science from experts who have shaped it, Forensic Anthropology: A Comprehensive Introduction Second Edition builds off of the success of the first edition and incorporates standard practices in addition to cutting-edge approaches in a user-friendly format, making it an ideal introductory-level text.Table of Contents AcknowledgementsAbout the EditorsAbout the ContributorsPrefacePart 1: Forensic Anthropology and the Crime SceneChapter One: Forensic Anthropology in the United States: Past and PresentMariaTeresa A. Tersigni-Tarrant and Natalie R. LangleyChapter Two: Skeletal Remains as EvidenceMarin A. Pilloud and MariaTeresa A. Tersigni-TarrantChapter Three: Forensic Archaeology: Survey Methods, Scene Documentation, Excavation, and Recovery MethodsDenise ToChapter Four: Forensic TaphonomyJames Pokines and MariaTeresa A. Tersigni-TarrantPart 2: The Skeleton and Skeletal DocumentationChapter Five: Human OsteologyMariaTeresa A. Tersigni-Tarrant and Natalie R. LangleyChapter Six: Human Odontology and the Dentition in Forensic AnthropologyDebra Prince Zinni and Kate M. CrowleyChapter Seven: Skeletal Examination and DocumentationLee Meadows JantzPart 3: Skeletal Individuation and AnalysesChapter Eight: Sex Estimation of Unknown Human RemainsGregory E. BergChapter Nine: Ancestry Methods: The Importance, The History And The PracticeM. Katherine Spradley and Katy E. WeisenseeChapter Ten: Age Estimation MethodsNatalie R. Langley, Alice F. Gooding, MariaTeresa A. Tersigni-TarrantChapter Eleven: Stature EstimationNatalie R. LangleyChapter Twelve: Pathological Conditions as Individuating Traits in a Forensic ContextDavid Hunt and Kerriann MardenChapter Thirteen: Analysis of Skeletal TraumaNatalie R. LangleyChapter Fourteen: Introduction to Fordisc 3 and Human Variation – StatisticsRichard L. Jantz and Stephen D. OusleyPart 4: Human Identification and Advanced Forensic Anthropology ApplicationsChapter Fifteen: Time Since Death Estimation and Bone Weathering: The Postmortem IntervalRebecca J. Wilson-Taylor and Angela M. DautartasChapter Sixteen: Methods of Personal IdentificationAngi M. Christensen and Bruce E. AndersonChapter Seventeen: Mass Fatalities, Mass Graves and the Forensic Investigation of International CrimesPierre Guyomarc’h and Derek CongramChapter Eighteen: Advanced Scene Topics: Fire and ComminglingJoanne Bennett Devlin and Nicholas P. HerrmannAppendix A: Application of Dentition In Forensic AnthropologyDebra Prince Zinni and Kate M. CrowleyAppendi

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Book SynopsisChronic obstructive pulmonary disease is, of 2024, one of the three main causes of death in the world, affecting around 12% of the world's population. Its incidence is estimated to increase in the coming decades due to continuous exposure to risk factors and to an aging population.Pulmonary emphysema is one of its most serious phenotypes, with chronic and inexorable progression and, in the most severe stages, it is highly disabling and lethal.This book reviews knowledge about the pathophysiology of severe pulmonary emphysema and the current innovative interventional and minimally invasive therapeutic concepts for the management of these advanced stages of emphysema, based on the best scientific evidence.This guide provides to multidisciplinary pulmonary boards of experts in advanced lung diseases, current criteria for the choice of precision therapeutic options and beyond to maintaining optimized medical treatment to controlling lung hyperinflation, and alleviat

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Book SynopsisâPrinciples and Practicalities of ENTâ ensures that doctors of all levels are well equipped to approach common clinical scenarios encountered in ENT with confidence. Each section covers how to prepare for patients, includes key points in the history and examination, and how best to investigate and manage a wide variety of common ENT presentations and conditions. The material is structured to provide an easy reference including red flag and primary care sections to enable readers to know what to look out for when considering referrals. Inaddition to being a revision tool for medical students, doctors pursuing MRCS (ENT) examinations and higher surgical training in ENT, this book also serves as a useful aid for primary care physicians in their everyday diagnostics and referral practices.Table of ContentsAcknowledgment. Author biographies. List of abbreviations. Section I Emergency. Otology. Mastoiditis. Necrotising otitis externa. Sudden sensorineural hearing loss. Temporal bone trauma. External ear trauma. Rhinology. Epistaxis. Orbital haematoma. Periorbital cellulitis. Nasal trauma. Head and neck. Adult acute airway obstruction. Acute paediatric airway obstruction. Penetrating and blunt neck trauma. Upper aerodigestive tract foreign body. Deep space neck infections. Post-tonsillectomy bleed. Post-thyroidectomy haematoma. Section II Elective. Otology. Hearing loss and audiology. Otitis externa. Acute otitis media. Cholesteatoma. Dizziness and vertigo. Tinnitus. Facial nerve palsy. Rhinology. Rhinosinusitis. Anosmia. Head and neck. Head and neck malignancy. Malignancy of unknown primary. Dysphonia. Thyroid lump. Salivary gland mass. Dysphagia. Paediatrics. Paediatric hearing loss. Paediatric sleep disordered breathing. Index.

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Book SynopsisEchocardiography is one of the most useful and powerful diagnostic tools in the assessment of cardiac structure and function. It remains a rapidly expanding modality, with new techniques constantly developing and maturing. Building on the success of the second edition, the third edition of Making Sense of Echocardiography: A Hands-on Guide provides a timely overview for those learning echocardiography for the first time as well as an accessible handbook that experienced sonographers can refer to. The strong clinical focus and concentration on real-life scenarios make this book relevant in day-to-day practice. Key updates for this edition include the latest guidelines for the evaluation of diastolic function and pulmonary hypertension, and fully updated reference intervals throughout.Key Features Covers not only the fundamentals of echocardiography including ultrasound physics, but also new technologies such as 3D echocardiography Provides Table of ContentsPrefaceAcknowledgementsAuthor biographyAcronyms and abbreviationsPart 1 Essential principles1. History of echocardiography2. Cardiac anatomy and physiology3. Physics and instrumentation4. Doppler physics5. Myocardial mechanics6. Service provisionPart 2 Cardiac imaging techniques7. The standard transthoracic echo study8. Transoesophageal echo9. Stress echo10. Contrast echo11. Tissue Doppler imaging12. Speckle tracking13. 3D echo14. Intravascular ultrasound and epicardial echo15. Alternative cardiac imaging techniquesPart 3 Clinical cases16. The left ventricle and its systolic function17. Coronary artery disease and regional left ventricular function18. Left ventricular diastolic function19. The left atrium20. The aortic valve21. The mitral valve22. The right ventricle 23. The right atrium24. The tricuspid valve25. The pulmonary valve26. Pulmonary hypertension27. Heart valve repair and replacement28. Endocarditis29. The cardiomyopathies30. The pericardium31. The aorta 32. Cardiac masses33. Congenital heart disease34. Common echo requestsAppendix - Echo resourcesIndex

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Book SynopsisAn essential handbook that covers the radiological findings of all the common surgical conditions. Candidates preparing for the MRCS or FRCS (in General Surgery) exams will find this indispensable guide will prepare them for a wide range of questions, including rare and obscure examples that are not found elsewhere. Radiological findings are presented according to systems such as colorectal, upper GI and HPB, urology, emergency surgery and others. Each chapter describes the use of radiological modalities in different clinical scenarios and includes figures illustrating the defining characteristics of common clinical scenarios.The clear and illustrated content provides the knowledge required to answer what would otherwise be some of the most difficult questions in postgraduate surgical examinations. It is also a practical reference book that can be kept at hand to inform ward rounds and multidisciplinary team meetings. MRCS and FRCS exam candidates are expected to have Table of ContentsChapter 1: Radiological Modalities Chapter 2: Emergency Surgery Chapter 3: Upper Gastrointestinal And Hepatobiliary Surgery Chapter 4: Colorectal Surgery Chapter 5: Breast Surgery Chapter 6: Vascular Surgery Chapter 7: Paediatric Surgery Chapter 8: Urology Chapter 9: Trauma And Orthopaedics Chapter 10: Neurosurgery, Ent And Endocrine Surgery

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Book SynopsisSmashing Core Surgical Training Interviews is a crucial roadmap through the highly competitive world of surgery, written by previous Core Surgical Training National Recruitment panel members. It provides a realistic understanding of what is expected on the interview day and how best to prepare for it.This is the perfect preparation guide for any medical student or junior doctor with a serious desire to launch a career in surgery in the United Kingdom by smashing the Core Surgical Training interviews.It covers all aspects of the interview, including how to prepare the portfolio, virtual interview etiquette, and post-interview considerations.This book contains: More than 35 clinical scenarios and more than 15 management scenarios with model answers Model frameworks for structuring answers Information covering real-life struggles, including how to maximise opportunities as a medical student, how to publish, and how to decide whether to taTable of ContentsForeword by Fiona Myint. Foreword by Roy Phitayakorn. Acknowledgements. Editors. List of Contributors. Introduction. Application Process for Core Surgical Training. Multi-Speciality Recruitment Assessment (MSRA). Preparing Your Surgical Portfolio. How to Publish. Mastering the Presentation. How to Structure Your Answers: Clinical. How to Structure Your Answers: Management. Virtual Interview Etiquette. Clinical Scenarios. Management Scenarios. Post-Interview Job Preferencing. Life as a Core Surgical Trainee. The Challenges of Life as a Core Surgical Trainee. To F3 or Not to F3. Medical Students – Planning a Career in Surgery. Women in Surgery. International Medical Graduates – Planning to a Move to the UK. International Medical Graduates – Planning a Career in Surgery. Dyslexia and Neurodiversity. Out in Surgery – LGBTQ Issues. Getting into Core Surgical Training as an Ethnic Minority. Index.

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Book SynopsisThis is an updated and comprehensive treatise on optical, medical, and surgical management of keratoconus with an exclusive panoramic view of all existing modalities for confronting this serious disabling morbidity affecting people in their youth. Early diagnosis and proper treatment can salvage vision and help patients to get back to their routines and enhance their quality of life. The contents include optical and glass prescription and contact lens fitting; CXL alone; and combined surgeries, phakic IOLs, and corneal transplantation. The illustrated and organized 360-degrees approach makes this a must-have manual for ophthalmology trainees, fellows, and professionals.Key Features: Focuses on optical management for keratoconus, with the latest updates on surgical management Covers a very interesting and relevant topic for ophthalmologists and cornea specialists, using a practical case-based format Uses evidence-

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Book SynopsisThis book fulfils the need of doctors, medical students, and all healthcare personnel for information that addresses fundamental patient safety concepts that are not usually covered in conventional medical curricula.There are three valuable features. Firstly, the content encompasses the main areas of human factors and patient safety in short and easily accessible language supplemented by anecdotes from safety-critical industries such as aviation and nuclear power. Secondly, each chapter highlights the problems of human error and provides solutions that help to reduce the risks to patients. Finally, the coverage highlights the important role the public should play in protecting their own safety when in contact with healthcare systems.

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Book SynopsisThis volume describes culture media and solutions used in human ART; how they have been developed for in vitro human pre-implantation embryo development, the function and importance of the various components in media and solutions and how they interact, and how the systems in which these are used can influence outcomes. Chapters discuss inorganic solutes, energy substrates, amino acids, macromolecules, cytokines, growth factors, buffers, pH, osmolality, and the interaction of these parameters. The role of incubators and other physical factors are reviewed, along with the relevance and prospects of emerging technologies: morphokinetic analysis using time-lapse imaging and dynamic fluid incubation systems. Results of prospective randomized trials are emphasized to ascertain the added value of these techniques for selecting viable embryos. This comprehensive guide will be invaluable for embryologists, physicians and all personnel involved in the fluid products used in human ART seeking toTable of ContentsForeword Alan Trounson; Part I. Culture Media and Solutions: 1. Overview Patrick Quinn; 2. Media and embryo interactions Patrick Quinn; 3. Female tract environment and its relationship to ART media composition Henry J. Leese and Sarah Louise Whitear; 4. Buffering systems in IVF Natalie A. Clark and Jason E. Swain; 5. Essential features in media development for spermatozoa, oocytes and embryos David Mortimer; 6. Macromolecular supplementation of embryo culture media Thomas B. Pool; 7. Monozygotic twinning and assisted reproduction. Laboratory or clinical? Marius Meintjes; 8. Amino acids and ammonium Deirdre Zander-Fox and Michelle Lane; 9. Growth factors and cytokines in embryo development Sarah A. Robertson and Jeremy G. Thompson; 10. Osmolality Jay M. Baltz; 11. pH control in the embryo culture environment Joe Conaghan; 12. In vitro maturation of immature human oocytes Ri-Cheng Chian, Shan-Jun Dai and Yao Wang; 13. Oocyte and embryo cryopreservation media Diana Patricia Bernal, Ching-Chien Chang and Zsolt Peter Nagy; 14. International regulation of ART media Theresa Jeary; Part II. Culture Systems: 15. Culture of embryos in dynamic fluid environments André Monteiro da Rocha and Gary Daniel Smith; 16. Time-lapse imaging of embryo development: using morphokinetic analysis to select viable embryos Markus H. M. Montag, Kamilla S. Pedersen and Niels B. Ramsing; 17. Optimizing culture conditions Kathleen A. Miller; 18. Low cost IVF Luca Gianaroli, M. Cristina Magli and Anna P. Ferraretti; 19. Incubators old and new Eduardo Kelly and Takeo Cho; 20. Incubator management William R. Boone and H. Lee Higdon, III; 21. Summary and conclusions Patrick Quinn; Index.

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Book SynopsisThis essential revision guide for the paediatric component of the FRCS (Tr and Orth) gives step-by-step guidelines to common operations and includes tips and tricks to guide trainee orthopaedic surgeons to success in their exams. This new edition has been fully updated and expanded, and includes details of the new examination format.Table of ContentsSection I. General Introduction: 1. Introduction and general preparation Paul A. Banaszkiewicz; 2. Clinical assessment Stan Jones and Sattar Alshryda; 3. Normal lower limb variants in children Manoj Ramachandran and Greg B. Firth; Section II. Regional Paediatric Orthopaedics: 4a. Slipped upper femoral epiphysis Sattar Alshryda and Paul A. Banaszkiewicz; 4b. Legg–Calvé–Perthes disease Sattar Alshryda and Paul A. Banaszkiewicz; 4c. Developmental dysplasia of the hip Sattar Alshryda and Paul A. Banaszkiewicz; 4d. Miscellaneous hip disorders Sattar Alshryda and Paul A. Banaszkiewicz; 5. Traumatic hip disorders Sean Duffy and Fergal Monsell; 6. Orthopaedic knee disorders Sattar Alshryda and Fazal Ali; 7. Traumatic knee disorders Nick Nicolaou and Joanna Thomas; 8. Orthopaedic foot and ankle disorders Anthony Cooper, Akinwande Adedapo and Stan Jones; 9. Traumatic foot and ankle disorders Vittoria Bucknall and Mohammed Al-Maiyah; 10. Orthopaedic spine disorders Ashley A. Cole and Lee M. Breakwell; 11. Traumatic spine disorders Ashley A. Cole and Lee M. Breakwell; 12. Orthopaedic shoulder disorders Om Lahoti and Tony Antonios; 13. Traumatic shoulder disorders Talal Al-Jabri, Sandeep Gokhale and Clare Carpenter; 14. Orthopaedic elbow disorders Om Lahoti and Matt Nixon; 15. Traumatic elbow disorders Thomas Dehler and John Davies; 16. Orthopaedic hand and wrist disorders Sara Dorman and Dean E. Boyce; 17. Traumatic wrist and hand disorders Ehab Aldlyami and Khalid Alawadi; Section III. Core Paediatric Orthopaedics: 18a. Lower limbs Simon L. Barker and Sattar Alshryda; 18b. Upper limbs Bavan Luckshman and Rachel Buckingham; 18c. Gait analysis Jennifer Walsh, Syed Kazmi and Tahani Al Ali; 19. Musculoskeletal infection Mark Gaston, Richard Gardner and Simon Kelley; 20. Musculoskeletal tumours Richard Gardner, Gino R. Somers and Sevan Hopyan; 21. Skeletal dysplasia Anish P. Sanghrajka and James A. Fernandes; 22. Metabolic bone disease Richard Hutchinson, Mubashshar Ahmad and Gavin DeKiewiet; 23. Deformity correction Stan Jones, Farhan Ali, Anthony Cooper and Alwyn Abraham; 24. Orthopaedic-related syndromes Deborah M. Eastwood; 25. Miscellaneous paediatric conditions Ben Marson and Kathryn Price.

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Book SynopsisThis new edition of Surgery at a Glance provides a concise and visually-orientated summary of a comprehensive lecture course in surgery. Following the easy-to-use at a Glance format, each topic is presented with clear illustrations and key facts encapsulating all that you need to know. The book is coherently divided into clinical presentations followed by major surgical conditions. Exploring core principals and important diseases, it is an accessible companion to any surgery core text, and is ideally placed to support the current curriculum. Surgery at a Glance: Features brand new chapters on Orthopaedics and updates on the management of surgical conditions Includes more revision-friendly elements for quick reference Is fully supported by a resource website atwww.testgeneralsurgery.com containing both MCQs and short answer questionsTrade Review“Although this book is intended for surgical residents (and some may find it useful), it is most appropriate for third- and fourth-year medical students (such as those doing sub-internships). It would be a valuable addition to other books that are standard for this demographic (e.g., Surgical Recall, 6th edition, Blackbourne (Lippincott Williams & Wilkins, 2012).” (Doody’s, 21 March 2014) “Surgery at a Glance deserves ongoing recommendation as it appears in an updated new fifth edition to provide students with a summary of a comprehensive lecture course in surgery. It's arranged in an 'at a glance' format, which provides quick visuals and easy keys to understanding, with key facts supplementing discussions of major surgical conditions. New chapters on Orthopaedics, updates on post-surgery management, and a website packed with supportive resources to the text makes for a volume filled with important insights any student will find important.” (Midwest Book Review, 1 December 2013)Table of ContentsPreface 6 List of abbreviations 7 Part 1 Clinical presentations at a glance 1 Neck lump 10 2 Dysphagia 12 3 Haemoptysis 14 4 Breast lump 16 5 Breast pain 18 6 Nipple discharge 20 7 Gastrointestinal bleeding 22 8 Dyspepsia 26 9 Vomiting 28 10 Acute abdominal pain 30 11 Chronic abdominal pain 32 12 Abdominal swellings (general) 34 13 Abdominal swellings (localized) – upper abdominal 36 14 Abdominal swellings (localized) – lower abdominal 40 15 Jaundice 42 16 Diarrhoea 44 17 Altered bowel habit/constipation 46 18 Groin swellings 48 19 Claudication 50 20 Acute warm painful leg 52 21 Acute ‘cold’ leg 54 22 Leg ulceration 56 23 Dysuria 58 24 Urinary retention 60 25 Haematuria 62 26 Scrotal swellings 64 27 Stomas and incisions 66 Part 2 Surgical diseases at a glance 28 Anaesthesia 68 29 Hypoxia 72 30 Surgical infection 74 31 Sepsis 78 32 Systemic infl ammatory response syndrome 80 33 Shock 82 34 Acute renal failure 84 35 Fractures 86 36 Orthopaedics – congenital and childhood disorders 88 37 Orthopaedics – metabolic and infective disorders 90 38 Arthritis 92 39 Musculoskeletal tumours 95 40 Burns 98 41 Major trauma – basic principles 100 42 Traumatic brain injury (head injury) 102 43 Gastro-oesophageal refl ux disease 106 44 Oesophageal carcinoma 108 45 Peptic ulcer disease 110 46 Gastric carcinoma 112 47 Malabsorption 114 48 Crohn’s disease 116 49 Acute appendicitis 118 50 Diverticular disease 120 51 Ulcerative colitis 122 52 Colorectal carcinoma 124 53 Benign anal and perianal disorders 126 54 Intestinal obstruction 128 55 Abdominal hernias 130 56 Gallstone disease 132 57 Pancreatitis 136 58 Pancreatic tumours 138 59 Benign breast disease 140 60 Breast cancer 142 61 Goitre 144 62 Thyroid malignancies 146 63 Parathyroid disease 148 64 Pituitary disorders 150 65 Adrenal disorders 152 66 Skin cancer 154 67 Ischaemic heart disease 157 68 Valvular heart disease 160 69 Peripheral arterial disease 162 70 The diabetic foot 164 71 Aneurysms 166 72 Extracranial arterial disease 168 73 Venous thromboembolism 170 74 Varicose veins 173 75 Lymphoedema 176 76 Postoperative pulmonary complications 178 77 Lung cancer 180 78 Urinary tract infection 182 79 Benign prostatic hypertrophy 184 80 Renal (urinary) calculi 186 81 Renal cell carcinoma 188 82 Carcinoma of the bladder 190 83 Carcinoma of the prostate 192 84 Testicular cancer 194 85 Urinary incontinence 196 86 Solid organ transplantation 198 87 Paediatric ‘general’ surgery 200 Index 204

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Book SynopsisPercutaneous renal procedures are highly complex and require a great deal of surgical skill. This book provides urologists, nephrologists and surgeons with the knowledge, confidence and clinical skills required to perform these complex and difficult surgical procedures safely and effectively.Table of ContentsContributor List, vii Preface, xiii About the Companion Website, xiv Section 1: Introduction 1 Percutaneous Renal Access: A Historical Perspective, 3 Simpa S. Salami, Zeph Okeke, and Arthur D. Smith 2 Interventional Imaging and Radiation Safety, 7 Don C. Arnold II, Kirk M. Anderson, and D. Duane Baldwin Section 2: Percutaneous Management of Large Renal Calculi (Percutaneous Nephrolithotomy) 3 Epidemiology of Large Renal Stones and Utilization Patterns of Percutaneous Nephrolithotomy, 23 Stephen Faddegon and Margaret S. Pearle 4 Evolution of Evidence-Based Outcomes for Percutaneous Nephrolithotomy, 31 Kirsten Foell and Kenneth T. Pace 5 Patient Selection and Informed Consent, 46 Nader Fahmy and John Denstedt 6 Instrumentation and Surgical Technique: Percutaneous Access, 59 Naeem Bhojani and James E. Lingeman 7 Instrumentation and Surgical Technique: Tract Dilation and Endoscopes, 64 Michael J. Metcalfe, Ryan Paterson, and Ben Chew 8 Instrumentation and Surgical Technique: Intracorporeal Lithotrites, 74 Abhishek P. Patel and Bodo E. Knudsen 9 Instrumentation and Surgical Technique: Step-by-Step Percutaneous Nephrolithotomy: Prone, 84 Mantu Gupta and Doh Yoon Cha 10 Instrumentation and Surgical Technique: Step-by-Step Percutaneous Nephrolithotomy: Supine, 95 Arvind Ganpule, Amit Doshi, and Mahesh R. Desai 11 Instrumentation and Surgical Technique: Step-by-Step Percutaneous Nephrolithotomy: Prone-Flexed/Lateral, 106 Kirsten Foell and R. John D’A. Honey 12 Instrumentation and Surgical Technique: Step-by-Step Percutaneous Nephrolithotomy: Endoscopic Guidance, 116 Farhan Khan, Ross Moskowitz, Joseph Graversen, Michael Ordon, Ralph V. Clayman, and Jaime Landman 13 Instrumentation and Surgical Technique: Step-by-Step Percutaneous Nephrolithotomy: Mini-Percutaneous Nephrolithotomy, 126 Gunnar Wendt-Nordahl and Thomas Knoll 14 Instrumentation and Surgical Technique: Step-by-Step Percutaneous Nephrolithotomy: Multiple Access, 134 Jessica N. Lange, Patrick W. Mufarrij, and Dean G. Assimos 15 Instrumentation and Surgical Technique: Step-by-Step Percutaneous Nephrolithotomy: Tube or Tubeless Percutaneous Nephrolithotomy, 143 Andreas Neisius, Michael E. Lipkin, and Glenn M. Preminger 16 Instrumentation and Surgical Technique: Postoperative Imaging Following Percutaneous Nephrolithotomy, 152 Aditya Bagrodia and Margaret S. Pearle 17 Instrumentation and Surgical Technique: Step-by-Step Antegrade Ureteric Stenting, 161 Ravi Kulkarni Section 3: Percutaneous Management of Transitional Cell Cancer (Percutaneous Resection of Tumor) 18 Epidemiology of Disease (Upper Tract Transitional Cell Cancer), 175 Matthew R. Hotston, Sunil Mathur, and Francis X. Keeley 19 Evidence-Based Outcomes for Percutaneous Management of Upper Tract Urothelial Carcinoma, 182 Eric R. Taylor and Marshall L. Stoller 20 Patient Selection and Informed Consent, 190 Michael Conlin and Nicholas Tadros 21 Percutaneous Treatment of Upper Tract Urothelial Carcinoma, 196 Steve Dong, Matthew Dunn, and Mihir Desai Section 4: Percutaneous Ablation of Renal Cell Cancer (Thermal and Nonthermal) 22 Epidemiology and Biology of Small Renal Masses, 205 Paul L. Crispen and Steven C. Campbell 23 Evolution of Evidence-based Outcomes for Percutaneous Management, 215 Matthew J. O’Shaughnessy, David A. Leavitt, and J. Kyle Anderson 24 Patient Selection and Informed Consent, 224 Humberto Laydner and Jihad H. Kaouk 25 Instrumentation and Technique: Cryotherapy, 229 Achim Lusch, Jane Cho, Michael A. Liss, Joseph Graversen, and Jaime Landman 26 Instrumentation and Technique: Hyperthermal Ablation: Radiofrequency and Microwave Ablation, 237 Arturo Castro Jr, Lawrence Jenkins, Obi Ekwenna, John Shields, Nelson Salas, and Raymond Leveillee 27 Instrumentation and Technique: High-Intensity Focused Ultrasound, 253 Robert W. Ritchie, Tom Leslie, David Cranston, and Mark Sullivan 28 Instrumentation and Technique: Laser, 262 Ramakrishna Venkatesh, Jason R. Bylund, and Stephen E. Strup 29 Instrumentation and Technique: Irreversible Electroporation, 268 Chad R. Tracy and Jeffrey A. Cadeddu 30 Instrumentation and Techniques in Renal Radiosurgery, 276 Matthew J. Maurice, Gino J. Vricella, and Lee E. Ponsky 31 Instrumentation and Technique: Renal Histotripsy, 281 William W. Roberts Index, 290

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Book SynopsisMinor Surgery at a Glance is an essential companion for those who wish to learn or familiarise themselves with minor surgery, including trainees and practising surgeons, dermatologists, GPs, and emergency medicine physicians.Trade Review"This is a great teaching tool and an outstanding addition to the library of every student and attending clinicians as a ready reference source of minor surgical techniques. Weighted Numerical Score: 100 - 5 Stars" (Doody Enterprises 31/03/2017)Table of ContentsContributors vii Preface ix Part 1 Avoiding and Managing Problems: Principles of Safe Surgery 1 1 Consent 2 2 Physical environment 4 3 Set-up 6 4 Instruments 8 5 Infection control and prevention 10 6 Human factors 12 7 Focused history 14 8 Specimen processing and reporting 16 9 Follow-up 18 10 Anaphylaxis 20 11 Emergencies and resuscitation 22 12 Audit and practice 23 13 Communication and conflict resolution 24 Part 2 Basic Pain Control and Anaesthesia 27 14 Local anaesthesia 28 15 Sedation 30 16 General and regional anaesthesia 33 Part 3 Core Surgical Knowledge 37 17 Skin incisions 38 18 Principles of wound closure 40 19 Sutures 42 20 Needles 44 21 Diathermy 46 22 Dressings 48 23 Haemostasis 50 24 Hypertrophic and keloid scarring 52 Part 4 Practice of Minor Surgery 55 Elective Minor Surgery 55 25 Biopsy techniques 56 26 Benign and premalignant skin lesions 58 27 Melanoma 60 28 Non-melanoma skin cancer 62 29 Neck lumps 64 30 Sebaceous cysts 66 31 Lipoma 68 32 The reconstructive ladder 70 33 Cryotherapy for verrucae (plantar wart) 72 34 Muscle and nerve biopsy 74 35 Ingrown toenail 76 36 Lymph node excision 78 37 Sclerotherapy 80 38 Botulinum toxin 82 Emergency Minor Surgery 55 39 Tetanus 84 40 Scalp lacerations 86 41 Foreign bodies 88 42 Facial trauma and lacerations 90 43 Hand injuries 93 44 Trauma assessment 96 45 Psychosocial considerations 98 46 Incision and drainage of abscesses 100 47 Complications 102 48 Difficult locations 104 Index 105

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Book SynopsisPancreatitis: medical and surgical management provides gastroenterologists and GI surgeons, both fully qualified and in training, with a focused, evidence-based approach to the most exciting developments in the diagnosis and clinical management of pancreatitis. Focusing mainly on the rapidly changing and innovative medical and surgical strategies to manage the disease, new surgical procedures such as endoscopic biliary intervention and minimally invasive necrosectomy to exciting new medical therapies like Antiprotease, Lexipafant, probiotics and enzyme treatment are all discussed. Full colour throughout, with over 250 colour illustrations and with reference to the latest clinical guidelines from the AGA, ACG and UEGW at all times, it is an essential consultation tool for all those managing patients with this increasingly common condition.Trade Review"Overall, this is an excellent book on all aspects of acute and chronic pancreatitis. It is concise yet comprehensive, written by well-known and well-published, credible authorities. It will be useful not just to the intended audience of gastroenterologists and GI surgeons, but also to all physicians involved in the care of patients with pancreatitis. Most books try to cover all aspects of this complex condition in a summary fashion, which is not possible. This book fills in the gaps by providing a focused, comprehensive review including latest evidence and guidelines. 5 Stars!" (Doody Enterprises July 2017)"This is a definitive and authoritative work that is quite manageable to read, understand and process.Because of that, a reader will return to it often, extending its benefits. Pancreatitis is challengingenough without having what this book provides. This excellent contribution has indeed refreshed andadvanced my own knowledge-base by performing this review. Even the most seasoned practitioner cangarner value in its pages, and again, return to it often" Charles M. Vollmer, Jr, MD, Professor of Surgery, University of Pennsylvania Perelman School of Medicine on behalf of HPB, Summer 2017Table of ContentsList of contributors, vii 1 Epidemiology and genetics of chronic pancreatitis, 1 2A Pathobiology of the acinar cell in acute pancreatitis, 10 2B Locoregional pathophysiology in acute pancreatitis: pancreas and intestine, 19 2C Pathophysiology of systemic inflammatory response syndrome and multiorgan dysfunction syndrome in acute pancreatitis, 29 3 Diagnosis, prediction, and classification, 38 4 Medical treatment, 47 5 Nutritional treatment in acute pancreatitis, 55 6 Gallstone pancreatitis: diagnosis and treatment, 64 7 Treatment of local complications, 75 8 Treatment of systemic complications and organ failure, 85 9 Specific treatment for acute pancreatitis, 91 10 Sequelae of acute pancreatitis, 101 11 History of chronic pancreatitis, 113 12A Epidemiology and pathophysiology: epidemiology and risk factors, 118 12B Epidemiology and pathophysiology: genetic insights into pathogenesis, 126 12C Pancreatic stellate cells: what do they tell us about chronic pancreatitis?, 143 12D Autoimmune pancreatitis: an update, 152 12E Etiology and pathophysiology: tropical pancreatitis, 161 12F Mechanisms and pathways of pain in chronic pancreatitis, 169 13A Imaging of chronic pancreatitis, 179 13B Endoscopic ultrasonography in chronic pancreatitis, 188 14A Pancreatic enzyme replacement therapy (PERT), 195 14B Nutritional treatment: antioxidant treatment, 205 14C Pancreatogenic diabetes: etiology, implications, and management, 211 14D Nutrition without a pancreas: how does the gut do it?, 225 15A Endoscopic management of chronic pancreatitis, 233 15B Shocking and fragmenting pancreatic ductal stones, 245 15C Endoscopic management: celiac plexus blockade, 249 16A A brief history of modern surgery for chronic pancreatitis, 256 16B Surgery for chronic pancreatitis: indications and timing of surgery, 261 16C Chronic pancreatitis: surgical strategy in complicated diseases, 265 16D Surgery for chronic pancreatitis: pancreatic duct drainage procedures, 273 16E Surgical management: resection and drainage procedures, 279 16F The role of pancreatoduodenectomy in the management of chronic pancreatitis, 286 17A Total pancreatectomy and islet cell autotransplantation: patient selection, 295 17B Total pancreatectomy and islet cell autotransplantation: the science of islet cell preservation, from pancreas to liver, 299 17C Total pancreatectomy and islet cell autotransplantation: long-term assessment of graft function, 308 Index, 321

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Book SynopsisSurgery is a core element of the clinical practice of gynaecology. Bonney''s Gynaecological Surgery has been a firm favourite for gynaecological surgical practice since 1911. Specifically tailored for trainees in obstetrics and gynaecology, the text focuses on the most commonly performed procedures. The 12th edition will include a colour photo section. With greater emphasis on fundamental clinical skills and major updates on laparoscopic and robotic surgery, this classic text will be brought right up to date for the current trainee or junior consultant physician. Each chapter follows a consistent plan, guiding the reader through each procedure from anatomy and indications to post-op considerations and complications. The text is also accompanied by surgical illustrations of unparalleled quality, ensuring that this volume will remain a valuable resource for all clinicians specializing in gynaecological surgery.Table of ContentsPreface, vii Part 1: General 1 Introduction and prologue, 3 2 Preparation for surgery, 7 3 Instruments, operative materials and basic surgical techniques, 17 4 Opening and closing the abdominal cavity, 33 5 The laparoscopic approach in gynaecology, 45 6 Postoperative care and complications, 55 Part 2: Anatomical For the general gynaecologist and gynaecologist in training 7 Operations on the vulva, 63 8 Operations on the vagina, 71 9 Operations on the cervix, 83 10 Operations on the uterine cavity, 101 11 Operations on the uterus, 107 12 Uterine fibroids, 127 13 Operations on the fallopian tubes, 135 14 Operations on the ovaries, 141 15 Caesarean section, 147 Part 3: Urogynaecology 16 Operations for pelvic organ prolapse, 161 17 Operations for urinary incontinence, 193 18 Operations for urogenital fistulae, 231 Part 4: Oncology 19 Surgery for carcinoma of the vulva, 269 20 Vaginal cancer surgery, 281 21 Cervical cancer, 285 22 Uterine cancer, 309 23 Ovarian cancer, 313 24 Exenterative surgery, 319 Part 5: Operations on other organs 25 Vascular surgery: applications in gynaecology and gynaecological oncology, 331 26 Management of injuries to the urinary tract, 335 27 Operations on the intestinal tract for the gynaecologist, 349 28 Reconstructive procedures, 361 Index, 365

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Book SynopsisThis book offers a detailed, practical guide to incorporating minimally invasive cosmetic surgery into dental practice. Chapters thoroughly examine all aspects of using these materials in practice, and present step-by-step techniques for injecting and placing neurotoxins and fillers, with specific recommendations for product selection and in-depth information on case management. Anatomical drawings and clinical photographs depict the procedures and concepts described. From patient evaluation, treatment planning, and product selection to techniques, managing complications, and marketing the service, Neurotoxins and Fillers in Facial Esthetic Surgery provides a complete resource for using these techniques in practice. Coverage encompasses facial anatomy, neurotoxins, cosmetic fillers, hyaluronic acid dermal fillers, Radiesse calcium hydroxylapatite injectable filler, pearls and pitfalls, and how to build your practice. Offers a complete but easy-to-use-reference on all aspects of how to Table of ContentsList of Contributors xi Foreword xiii About the Companion Website xv 1 Facial Anatomy and Patient Evaluation 1Timothy Osborn and Bradford M. Towne 1.1 Facial Anatomy 1 1.2 Anatomy of Facial Skin 1 1.3 Anatomy of the Superficial Fat Compartments 2 1.4 Anatomy of the Facial Fasciae 3 1.5 Anatomy of the Facial Mimetic Muscles 5 1.6 Anatomy of the Deep Facial Fat Compartments 7 1.7 Anatomy of the Ligamentous Structures (Retaining Ligaments) of the Face 8 1.8 The Blood Supply of the Face 10 1.9 The Aging Face 10 1.10 Patient Selection, Assessment, Records 13 1.11 Patient Selection and Assessment 14 1.12 Treatment Sequencing 15 References 2 Neurotoxins: The Cosmetic Use of Botulinum Toxin A 19Jon D. Perenack and Shelly Williamson‐Esnard 2.1 Botulinum Neurotoxins Introduction 19 2.2 Botulinum Toxins Physiology and Characteristics 20 2.3 Manufacturing Process 20 2.4 Clinical Usage 24 2.4.1 Age of Patient Treated 25 2.4.2 Storage and Preparation of BoNTA 26 2.4.3 Patient Preparation and General Injection Tips 28 2.4.4 Treatment Recommendations for Specific Areas 30 2.4.4.1 Glabella 30 2.4.4.2 Forehead 32 2.4.4.3 Crow’s Feet – Lateral Orbital Lines 32 2.4.4.4 Indirect Browlift 35 2.4.4.5 Correcting Brow Asymmetry 35 2.4.4.6 Other Midface Techniques: Bunny Lines 36 2.4.4.7 Perioral Modifications with BoNTA 36 2.4.4.8 Treatment of Platysmal Bands 39 2.5 Treating Facial Asymmetries Secondary to Muscle Paralysis 41 2.6 Post‐ treatment Recommendations and Complications 41 2.7 Conclusion 42 References 43 3 Cosmetic Fillers 47Alexandra Radu and Faisal A. Quereshy 3.1 History of Cosmetic Fillers 47 3.1.1 Emergence of Autologous Fillers 48 3.1.2 Emergence of Non‐autologous Fillers 48 3.1.2.1 Silicones 49 3.1.2.2 Bovine Collagen 49 3.1.2.3 Porcine Collagen 49 3.1.2.4 Polymethylmethacrylate (PMMA) 49 3.1.2.5 Hyaluronic Acid 50 3.1.2.6 Dextran Beads in Hyaluronic Acid 50 3.1.2.7 Poly‐l‐lactic Acid 50 3.1.2.8 Calcium Hydroxylapatite 50 3.1.2.9 Polyvinyl Microspheres Suspended in Polyacrylamide 51 3.1.2.10 Polytetrafluoroethylene (PTFE) 51 3.1.2.11 Polyoxyethylene and Polyoxypropylene 51 3.2 Classification 51 3.2.1 Biodegradable Facial Fillers 51 3.2.2 Autologous and Allogeneic Facial Fillers 51 3.2.3 Xenograft Facial Fillers 53 3.2.4 Synthetic Facial Fillers 53 3.2.5 Nonbiodegradable Facial Fillers 53 3.3 Ease of Use 53 3.4 Benefits 55 3.5 Complications 58 References 61 4 Hyaluronic Acid Dermal Fillers 63Tirbod Fattahi and Salam Salman 4.1 Introduction 63 4.2 Hyaluronic Acid 63 4.3 Available Products 64 4.4 Clinical Indications 64 4.5 Injection Techniques 64 4.6 Selection Process 65 4.7 Reversibility of HA Fillers 65 4.8 Clinical Scenarios 66 4.8.1 Nasolabial Grooves 66 4.8.2 Lips 66 4.8.3 Tear Troughs 66 4.8.4 Glabella 67 4.9 Post‐ Injection Instructions 68 4.10 Longevity of HA Fillers 68 4.11 Conclusion 69 References 69 5 Radiesse™ Calcium Hydroxylapatite Injectable Filler 71Nikita Gupta, Onir L. Spiegel, and Jeffrey H. Spiegel 5.1 Treatment in Practice 72 References 74 6 Pearls and Pitfalls of Neurotoxins and Facial Fillers 75Raffi Der Sarkissian 6.1 Pearls and Pitfalls in Neurotoxin Use 75 6.2 Neurotoxin Preparation and Storage 75 6.3 Choice of Syringes and Needles 76 6.4 Basic Injection Principles 77 6.5 Specific Injection Pearls Based on Injection Site 78 6.5.1 Glabellar Techniques 78 6.5.2 Forehead Techniques 80 6.5.3 Periorbital Techniques 81 6.5.4 Treatment of Bunny Lines 83 6.5.5 Depressor Anguli Oris Techniques 83 6.5.6 Perioral Techniques 83 6.5.7 Levator Labii Superioris alaeque Nasi 84 6.5.8 Techniques for Chin Dimpling 85 6.5.9 Treatment of Platysmal Bands 85 6.5.10 Treatment for Masseter Hypertrophy 86 6.6 Neurotoxin Complications 87 6.7 Cosmetic Facial Fillers: Pearls and Pitfalls 88 6.8 Technical Pearls 91 6.9 Needles vs. Cannulas 92 6.10 Specific Injection Pearls 92 6.10.1 Fine Lines 92 6.10.2 Melolabial Groove 92 6.10.3 Labiomandibular Groove 93 6.10.4 Pre Jowl Sulcus 93 6.10.5 Labiomental Groove 93 6.10.6 Midface Volumization 94 6.10.7 Temporal Hollows 96 6.10.8 Lips 97 6.10.9 Nasojugal Groove 97 6.11 Complications of Facial Fillers 99 6.11.1 Bruising 99 6.11.2 Nodules 99 6.11.3 Overcorrection 99 6.11.4 Tyndall Effect 100 6.11.5 Calcium Hydroxylapatite 100 6.11.6 Sculptra 100 6.11.7 Granuloma Formation 100 6.11.8 Vascular Compromise 100 References 102 7 Building Your Practice 103Jay R. Levine 7.1 Internet Marketing: What’s in it for you? 103 7.2 Promoting Your Practice: Formulating a Strategy 103 7.3 Website Design Companies 104 7.4 Building Your Brand 104 7.5 Print Marketing 104 7.6 Website Design: Choosing a Designer 104 7.6.1 Other Items to Consider when Choosing a Website Designer 105 7.6.2 Designing Your Website 106 7.6.2.1 Connect with the User 106 7.6.2.2 Outside Perspective 106 7.6.2.3 Accuracy 106 7.6.2.4 Doctor Bios – How Important Are They? 106 7.6.2.5 Accessibility 106 7.6.2.6 Additional Features 107 7.6.3 SEO: More on Search Engines 107 7.6.3.1 Five Basic SEO Steps you can Take Yourself 107 7.6.3.2 Blogging 108 7.6.3.3 SEO: When to Call in the Experts 108 7.6.4 Online Ads: PPC with Google AdWords 108 7.6.4.1 Managing AdWords 108 7.6.5 Social Media: Getting Started 108 7.6.5.1 The Three Es of Social Marketing 108 7.6.5.2 How to Gain Followers 109 7.6.5.3 Facebook 109 7.6.5.4 Instagram 109 7.6.5.5 Twitter 109 7.6.5.6 YouTube 109 7.6.5.7 Pinterest 110 7.6.5.8 LinkedIn 110 7.7 Protecting Your Practice Online 110 7.8 Internet Marketing: Measuring Your Progress 110 7.9 Marketing Is Communication 110 References 111 Index 113

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Book SynopsisA concise and convenient pocket guide to interventional cardiology's latest procedures and technologies Interventional cardiology is growing more and more integral to the modern-day management of cardiovascular problems. Indeed, trainees are taught interventional methods as a matter of course. With a widening range of options open to them, however, the practicing cardiologist must be diligent and discerning when selecting the appropriate course of action for each patient, adapting their strategy as circumstance demands. Developing the skills and experience necessary to make these key judgments can be a challenging and lengthy process. Bringing together the knowledge of an international group of over 50 experts, this fifth edition of the Practical Handbook of Advanced Interventional Cardiology helps cardiologists of all levels to find interventional solutions to a wide range of problems. Its revised contents cover topics including new devices, valve procedures, and venous and atrial Table of ContentsPreface viii Contributors xi Foreword xx Acknowledgements xxii 1 Vascular Access 1Thach N. Nguyen, Nguyen Hong Phat, Phuoc T. Nguyen, and Tri Pham 2 Dynamic Coronary Angiography and Flow 29Thach N. Nguyen, Ernest F. Talarico Jr., Lê Xuân Minh Phúc, Duy Khanh Nguyen, Robert Luscomb Jr., and The‐Hung Nguyen 3 Guides 73Dobrin Vassilev, Pham Nhu Hung, Luan M. Ngo, Duy Chung, and Thach N. Nguyen 4 Wires 109Thach N. Nguyen, Nguyen Van Lanh, Huynh Dang Thanh Phuong, and Nguyen Thi Kim Dung 5 Balloon Angioplasty 125Thach N. Nguyen, Kim Truong, Quoc V.P. Bui, Ria Shah, Thien Bui, and Truong An Ngo 6 Stenting 140Thach N. Nguyen, Nguyen Van Thuan, Vy Le, Riichi André Ota González, and Ami R. Shah 7 Bioresorbable Vascular Scaffolds 167Michael Nguyen, Julia Isbister, Imran Sheikh, Tan Huay Cheem, Azeem Latib, and Nigel Jepson 8 Transradial Approach 186Jack Chen, Sandeep Nathan, Kwan S. Lee, Nguyen Thuong Nghia, Xian Kai Li, and Thach N. Nguyen 9 Slender Transradial Intervention 225Yuji Ikari 10 Left Main Percutaneous Coronary Intervention 239Michael S. Lee, Richard Shlofmitz, and Duk‐Woo Park 11 Chronic Total Occlusion 257Minh N. Vo, Sundeep Mishra, Mohamad Lazkani, Shishir Murarka, and Ashish Pershad 12 Ostial Lesions 310Szabolcs G. Szabo, Gautam Kumar, and Thach N. Nguyen 13 Acute ST‐segment Elevation Myocardial Infarction 331Jonathan Soverow, Son Truong Pham, Thai Truong, Quan H. Nguyen, Thach N. Nguyen, Alan Fong, and C. Michael Gibson 14 Interventions in Patients after Coronary Artery Bypass Graft 364Faisal Latif, Timir Paul, Thach N. Nguyen, Xu Bo, and Runlin Gao 15 Bifurcation Lesion 388Christian Stumpf, Shao Liang Chen, Imad Sheiban, and Dobrin Vassilev 16 Complications 420Nguyen Ngoc Quang, Nguyen Duc Cong, Duc Duy Nguyen, and Thach N. Nguyen 17 High‐risk Patients 467Sandeep Nathan, Vien Truong, Florian Krackhardt, Hoang Cong Nguyen, Thu Quynh Nguyen, Tra T. Ngo, Toan H.D. Le, and Thach N. Nguyen 18 Coronary Atherectomy 486Michael S. Lee and Arthur Lee 19 Removal of Embolized Material 505Thach N. Nguyen, Truong Quang Binh, Vu Tri Loc, Nguyen Si Tuan, and Duc Trung Truong 20 Subclavian Artery Interventions 523Gianluca Rigatelli, Elise Strum Anderson, Ali Otto, and Aravinda Nanjundappa 21 Renal Artery Interventions 539Gianluca Rigatelli, Frank Annie, Thi Anh Nga Nguyen, and Ho Thuong Dzung 22 Carotid Artery Occlusive Disease 553Gianluca Rigatelli, Hung D. Huynh, Dinh Duc Huy, and Horst Sievert 23 Iliac Artery Stenosis 580Gianluca Rigatelli, Aravinda Nanjundappa, Nelson Bernardo, Vijay Dave, and Cao van Thinh 24 Infrainguinal and Infragenicular Interventions 603Gianluca Rigatelli, Robert S. Dieter, Ali Foorq, Le Cao Phuong Duy, and Aravinda Nanjundappa 25 Pulmonary Embolism 624Faisal Latif, Mihas Kodenchery, Tram B. Nguyen, Nie Shao‐Ping, Tarneem Darwish, and Zeeshan Khan 26 MitraClip™ Mitral Valve Repair System 639Srinivas Iyengar, James Nguyen, and Edgar Tay 27 Septal Puncture and Inoue‐balloon Mitral Valvuloplasty 652Pham Manh Hung and Nguyen Ngoc Quang 28 Retrograde Percutaneous Aortic Valvuloplasty 690Ted Feldman, Thach N. Nguyen, Debabrata Dash, and Duane S. Pinto 29 Watchman™ Left Atrial Appendage Closure Device 701Srinivas Iyengar, James Nguyen, Edgar Tay, and Dongming Hou 30 Interventions in Acute Ischemic Stroke 714Le Van Truong, Nguyen Trong Tuyen, Ernest F. Talarico Jr., and Thach N. Nguyen Index 738

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Book SynopsisTRANSCATHETER MITRAL VALVE THERAPIES An essential survey of the advancing field of transcatheter mitral valve repair and replacementMinimally invasive transcatheter therapies have revolutionized the treatment of structural heart disease. Greatly improving outcomes for higher-risk patients, transcatheter aortic valve replacement is now established as a safe and effective alternative to invasive surgery. The mitral valve, however, poses further challenges. Contending with one of the heat's most anatomically and pathologically complex components, practitioners and engineers have yet to perfect a stream-lined, widely deliverable therapythough they are getting closer and closer to this goal. Transcatheter Mitral Valve Therapies provides a far-reaching survey of the field of mitral interventions in its current state. Highlighting the stumbling blocks preventing transcatheter mitral valve replacement's widespread adoption, the book's international group of contributors discuss the improvemeTable of ContentsList of Contributors xvii Introduction—The Mitral Book xxiii 1 The Pathology of Mitral Valve Disease 1Maria E. Romero, Sho Torii, and Renu Virmani 1.1 Introduction 1 1.2 General Anatomy of the Mitral Valve 1 1.2.1 Mitral Annulus 1 1.2.2 Leaflets 3 1.2.3 Chordae Tendineae and Papillary Muscles 5 1.2.4 Papillary Muscles and Left Ventricle 5 1.3 Pathology of Mitral Valve 5 1.3.1 Mitral Valve Stenosis 5 1.3.2 Aging Changes and Mitral Annulus Calcification (MAC) 6 1.3.3 Acute Mitral Regurgitation 8 1.3.4 Chronic Mitral Regurgitation 8 1.3.5 Degenerative MR; Myxomatous Degeneration of the Mitral Valve 8 1.3.6 Functional MR 10 References 11 2 The Importance of Minimally Invasive Approaches for Mitral Valve Repair 15Bobby Yanagawa and Niv Ad 2.1 Introduction to Minimally Invasive Mitral Valve Surgery 15 2.2 The Importance of MICS MVS 16 2.3 Patient Selection 17 2.4 Surgical Setup—Fibrillating Heart MVS 18 2.5 Alternatives for Cannulation 19 2.6 Alternatives to Myocardial Protection 19 2.7 Mitral Valve Repair 20 2.8 Outcomes 20 2.9 Initiating Minimally Invasive Mitral Valve Repair Program 21 2.10 Conclusion 22 References 22 3 When to Intervene—Should Surgical Guidelines Apply to Transcatheter Techniques in Treating MitralRegurgitation? 25Samir Kapadia, Rishi Puri, Kinjal Banerjee, and Lars G. Svensson 3.1 Introduction 25 3.2 Primary MR 25 3.2.1 Current Guideline Recommendations 25 3.2.2 Transcatheter Therapies—New Guideline Applications? 26 3.3 Secondary MR 29 3.3.1 Current Guideline Recommendations 29 3.4 Conclusions 31 References 32 4 Transcatheter Mitral Valve Therapies: A Three-Dimensional Echocardiographic View 35Shmuel Schwartzenberg, Chaim Yosefy, and Alexander Sagie 4.1 Introduction 35 4.1.1 Mitral Valve Anatomy 35 4.1.2 Mitral Valve Structure and Function 35 4.1.3 Mitral Regurgitation Severity 36 4.1.4 Diagnosis of MR Severity: Proximal Isovelocity Surface Area Method 36 4.1.5 Diagnosis of MR Severity: Vena Contracta Method 37 4.1.6 Primary and Secondary MR 37 4.1.7 Mitral Regurgitation and Cardiovascular Death and Morbidity 38 4.1.8 Screening for MitraClip Suitability 40 4.1.9 MitraClip Procedure Guidance 41 4.1.10 Transseptal Puncture 41 4.1.11 MitraClip Delivery Guidance 42 4.1.12 Adequacy of MitraClip Implantation Assessment 43 4.1.13 Other Technologies 45 4.2 Conclusions 45 References 45 5 CMR Assessment of Mitral Regurgitation 51Daniel Knight and Vivek Muthurangu 5.1 Introduction 51 5.2 Pulse Sequences Used in CMR 52 5.2.1 Cine Imaging 52 5.2.2 Phase Contrast Imaging 52 5.3 Assessment of MR Severity 52 5.3.1 Qualitative Assessment 52 5.3.2 Quantitative Assessment 55 5.3.3 Technical Considerations for the Quantitative Assessment of MR by CMR 56 5.4 Identification of MR Etiology 57 5.4.1 Primary MR 57 5.4.2 Secondary MR 57 5.5 The Role of CMR Assessment of MR in Clinical Practice 58 5.6 Conclusions 58 References 58 6 CT Planning for TMVR and Predicting LVOT Obstruction 63Dee Dee Wang, Mayra Guerrero, Brian O’Neill, Pedro A. Villablanca Spinetto, James Lee, Tiberio Frisoli, Marvin Eng, and William O’Neill 6.1 Introduction 63 6.2 History of Imaging for Mitral Valve Disease 63 6.2.1 TAVR CT Planning 63 6.2.2 Surgical and Transcatheter Mitral Interventions 63 6.3 Concept of Aortic and Mitral Valve Technology Development 64 6.4 Basics of CT Imaging Acquisition 66 6.5 Definition of Mitral Valve and TMVR device Landing Zone 66 6.6 Definition of LVOT 66 6.7 CT Methods for Neo-LVOT prediction modeling 67 6.8 CT Validation of Neo-LVOT Prediction Modeling Post-TMVR 68 6.9 Correlation Between Pre- and Post-TMVR CT Neo-LVOT Prediction Modeling 69 6.10 What Else Has CT Planning for TMVR Taught Us? 70 Acknowledgments 72 References 72 7 General Principles and State-of-the-Art Echocardiographic Evaluation of the Mitral Valve 75Federico M. Asch and Diego Medvedofsky 7.1 Introduction 75 7.2 Mechanism and Etiology of Chronic MR 75 7.2.1 Transthoracic Echocardiography 76 7.2.1.1 Assessment of MR Severity 76 7.2.2 Qualitative Assessment 76 7.2.2.1 Color Flow Doppler 76 7.3 Continuous Wave (CW) Density Jet 79 7.3.1 Semi-Quantitative Assessment 79 7.3.1.1 VC Width 79 7.4 Pulmonary Vein Flow/Mitral Inflow 79 7.4.1 Quantitative Assessment 80 7.5 Selection of Best Candidates for Interventions of the Mitral Valve 82 7.5.1 Echocardiographic Criteria of COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation) Trial 84 References 84 8 Intraprocedural Echocardiography for MitraClip 87Philip Haines and Sumbal A. Janjua 8.1 Introduction 87 8.2 Pre-Procedure Evaluation 88 8.3 Importance of the Baseline Study – TEE 88 8.4 The Transseptal Puncture 95 8.5 Guiding MitraClip System to Mitral Valve 98 8.6 Intraprocedural Guidance of Clip within Mitral Valve and Leaflets 102 8.7 Post-Clip-Deployment Assessment of Mitral Valve Function 103 8.8 Assessment of Complications and Iatrogenic ASD 105 References 112 9 Intraprocedural Echocardiography for Transcatheter Mitral Valve Replacement 115Patrick T. Gleason, John C. Lisko, and Stamatios Lerakis 9.1 Introduction 115 9.2 Baseline Mitral Valve Assessment 115 9.3 Access to the Left Atrium, Left Ventricle, and Mitral Valve 116 9.4 Predeployment and Deployment Monitoring 118 9.5 Postdeployment Evaluation 120 References 122 10 Transcatheter Repair: MitraClip for Degenerative Mitral Regurgitation 125Ted Feldman 10.1 Surgery for Degenerative Mitral Regurgitation 125 10.2 Evidence Base for MitraClip 125 10.3 Challenges for the MitraClip Procedure 130 10.4 Evaluation of MitraClip for Less than Prohibitive-Risk DMR Patients 131 10.5 Future Directions for MitraClip and Alternative Approaches for Leaflet Repair 133 10.6 Summary 135 References 136 11 MitraClip™ for Secondary Mitral Regurgitation 139Brian J. Forrestal and Toby Rogers 11.1 Introduction 139 11.2 European and US Clinical Practice Guidelines 139 11.3 The MitraClip System 140 11.4 MitraClip Preprocedural Planning 140 11.5 Surgical Outcomes Data 140 11.6 The COAPT and MITRA-FR Trials 141 11.7 Summary and Conclusions 144 References 144 12 The Edwards PASCAL Transcatheter Valve Repair System 147Mirjam Winkel, Stephan Windecker, and Fabien Praz 12.1 Introduction 147 12.2 The Edwards PASCAL™ Transcatheter Valve Repair System 147 12.3 Implantation Procedure 148 12.4 Compassionate-Use and Early Feasibility Data 150 12.5 Future Developments 151 References 152 13 The Development of a Novel Percutaneous Treatment for Secondary Mitral Regurgitation—The Carillon® Mitral Contour System® 153Steven L. Goldberg 13.1 Introduction 153 13.2 REDUCE-FMR 157 13.3 The CARILLON Trial 160 13.4 Summary 161 References 161 14 A Fully Percutaneous Mitral Ring: The Cardioband System 163Antonio Mangieri, Enrico Poletti, and Azeem Latib 14.1 Introduction 163 14.2 Mitral Annulus Anatomy 163 14.3 Pathophysiological Role of the Mitral Annulus in Mitral Regurgitation 164 14.3.1 Mitral Annulus in FMR 164 14.3.2 Mitral Annulus in DMR 164 14.4 Surgical Annuloplasty in Mitral Regurgitation 164 14.5 The Cardioband System: Description of the Device 165 14.6 Procedural Planning 165 14.7 Clinical Studies 168 14.8 Possible Complications Related to the Implantation of Cardioband 170 14.9 Recurrence of Mitral Regurgitation Following Cardioband Implantation 171 14.10 Cardioband in Combination with Other Devices 172 14.11 Conclusions 173 References 173 15 Transcatheter Mitral Cerclage Annuloplasty 175Christopher Bruce, June-Hong Kim, Toby Rogers, and Robert J. Lederman 15.1 Introduction 175 15.2 Cerclage Anatomy and Function 175 15.3 Limitations of Coronary Sinus Annuloplasty 176 15.4 Cerclage Annuloplasty Device 177 15.5 The Cerclage Procedure 177 15.6 Preclinical Experiments 178 15.7 Initial Human Experience 178 15.8 Future Directions 180 15.9 Summary 182 Competing Interests 183 References 183 16 The Transapical Off-Pump Mitral Valve Repair with the NeoChord Implantation (TOP-MINI) 185Stefan Bertog, Laura Vaskelyte, Nalan Schnelle, Iris Grunwald, Ilona Hofmann, Sameer Gafoor, Markus Reinartz, Predrag Matic, Bojan Jovanovic, Kolja Sievert, Michèle Jaqueline Lembens, and Horst Sievert 16.1 Introduction 185 16.2 Technology 185 16.3 Patient Selection 186 16.4 Procedure 186 16.5 Echocardiographic Guidance 191 16.6 Examples 191 16.6.1 Ideal Anatomy 191 16.6.2 Acceptable Anatomy 191 16.6.3 Challenging Anatomy 192 16.6.4 Data 192 16.7 Conclusion 194 References 195 17 AltaValve™—A Transcatheter Mitral Valve Regurgitation Treatment Technology 197Katherine Kumar, PhD and Saravana Kumar, PhD 17.1 Clinical Need 197 17.2 Device Description 198 17.2.1 Principle of Operation 198 17.2.2 Device Construction 199 17.2.2.1 Stent 200 17.2.2.2 Stent Cap 200 17.2.2.3 Tissue Valve 200 17.2.2.4 Fabric Skirts and Sutures 200 17.2.3 Delivery Systems 200 17.3 Anatomical Imaging and Sizing 202 17.4 Preclinical and Clinical Experience 203 17.4.1 Animal Studies 203 17.5 Human Clinical Experience 204 17.6 Summary 205 References 206 18 The ARTO Transcatheter Mitral Valve Repair System 209Andrejs Erglis, Inga Narbute, Agnese Strenge, and Samantha E. Greene 18.1 Device Description 209 18.2 Procedural Details 209 18.3 Clinical Experience with the ARTO System 212 18.4 Unique Features of the ARTO System 216 References 216 19 Transcatheter Mitral Annuloplasty: The Millipede Device 219Jason H. Rogers and Steven F. Bolling 19.1 Background 219 19.2 The Millipede Device 219 19.3 Millipede Implantation Procedure 220 19.4 Surgical Millipede Implants 220 19.5 Millipede Clinical Results 222 19.6 Clinical Implications 223 19.7 Summary 226 Author Disclosures 226 References 226 20 Transapical and Transseptal Access for Transcatheter Mitral Valve Replacement: Techniques and Devices 227James Edelman and Vinod H. Thourani 20.1 Introduction 227 20.2 Transapical Approach 227 20.2.1 Technique 228 20.2.2 Devices in Active Clinical Trial Phase 230 20.2.2.1 Tendyne 230 20.2.2.2 Intrepid 230 20.2.2.3 CardiAQ 231 20.2.2.4 TIARA 231 20.2.2.5 HighLife 231 20.3 Transseptal Approach 231 20.3.1 Technique 231 20.3.2 Devices in Active Clinical Trial Phase 233 20.3.2.1 Sapien M3 233 20.3.2.2 EVOQUE 233 20.3.2.3 Caisson 233 20.4 Conclusions 233 References 233 21 Mitral Valve-in-Valve and Valve-in-Ring Therapies 235Norihiko Kamioka, Peter C. Block, Adam B. Greenbaum, and Vasilis C. Babaliaros 21.1 Overview 235 21.2 Evidence 236 21.3 Procedure Planning 239 21.4 Procedure 243 21.5 Pitfalls and Solutions—POULEZ and LAMPOON 244 References 245 22 Edwards SAPIEN in Native Mitral Annular Calcification (MAC) 251Mayra Guerrero, Dee Dee Wang, Mackram Eleid, Charanjit Rihal, William O’Neill, and Ted Feldman 22.1 Introduction 251 22.2 Anatomic Considerations and Sizing 251 22.3 Delivery Access Types 253 22.4 Preprocedural Planning 253 22.5 Valve Deployment Technique 253 22.6 Clinical Outcomes and Complications 255 22.7 LVOT Obstruction 256 22.8 TMVR in MAC Clinical Trials 256 22.9 Aortic THV versus Dedicated TMVR Devices for MAC 257 22.10 Conclusions 257 Disclosures 258 References 258 23 Transcatheter Mitral Valve Replacement: The Tendyne Device 261Alison Duncan 23.1 Introduction 261 23.2 The Tendyne TMVI Device 261 23.2.1 Current Tendyne Device Design 262 23.3 Patient Screening and Preprocedural Imaging 262 23.3.1 Patient Selection 262 23.3.2 Anatomical Screening 263 23.4 Implantation Technique 264 23.4.1 Transapical Approach 264 23.4.2 Device Entry into Left Atrium 264 23.4.3 Intra-annular Device Deployment 264 23.4.4 Apical Pad Fixation and Adjustment of Tether Tension 264 23.4.5 Confirmation of Device Position and Function 267 23.5 Clinical Outcomes 267 23.6 Future Challenges 271 23.7 Conclusion 274 References 274 24 TIARA Transcatheter Mitral Replacement System 277Anson Cheung 24.1 Introduction 277 24.2 Neovasc TIARA TMVR System 277 24.3 Candidacy for TIARA TMVR 278 24.4 Clinical Case and TIARA TMVR Implantation 278 24.5 Clinical Updates 281 24.6 Conclusions 281 Conflict of Interest 282 References 282 25 Caisson Transcatheter Mitral Valve Replacement System 283Mathew R. Williams and Cezar S. Staniloae 25.1 Introduction 283 25.2 Caisson Transcatheter Mitral Valve Replacement System Components 283 25.2.1 Anchor 284 25.2.2 Valve 285 25.2.3 The Delivery System 285 25.2.4 Retrieval Accessories 285 25.3 Procedural Details 285 25.3.1 Role of Imaging on Valve Sizing and Procedural Guidance 287 25.3.1.1 Role of Gated CT 287 25.3.1.2 Role of TEE Guidance During the Procedure 288 25.4 Current Status of the Caisson Research Program 289 25.5 Conclusions 289 Reference 289 26 Transcatheter Mitral Valve Replacement with the CardiAQ-Edwards and EVOQUE Prostheses 291Howard C. Herrmann, Wilson Y. Szeto, and Frank E. Silvestry 26.1 Introduction 291 26.2 Device Description 291 26.3 First-in-Human Transfemoral Case 292 26.4 Initial Experience via Transapical Approach 292 26.5 Second-Generation Transseptal Approach 293 26.6 Current CardiAQ Generation Design and Contemporary Case Example 293 26.6.1 Evolution to EVOQUE TMVR 295 26.7 Discussion 296 References 297 27 Intrepid 299Eberhard Grube and Jan-Malte Sinning 27.1 Background 299 27.2 The Intrepid Valve Features 300 27.3 Clinical Experience 301 27.4 Discussion 304 References 306 28 Laceration of the Anterior Mitral Leaflet to Prevent Outflow Obstruction (LAMPOON) 309Jaffar M. Khan and Vasilis C. Babaliaros 28.1 Introduction 309 28.1.1 Mechanism of LVOT Obstruction from TMVR 309 28.1.2 Prediction of LVOT Obstruction 309 28.1.3 Prevention and Treatment of LVOT Obstruction 309 28.2 The LAMPOON Technique 310 28.2.1 CT Planning for TMVR and LAMPOON 311 28.2.2 LAMPOON Equipment 312 28.2.3 Step 1: Positioning the Snare System 312 28.2.4 Step 2: Leaflet Traversal 312 28.2.5 Step 3: Leaflet Laceration 312 28.3 Alternative LAMPOON Techniques 313 28.3.1 Antegrade Transseptal LAMPOON 313 28.3.2 Antegrade Apical LAMPOON 313 28.3.3 “Rescue” LAMPOON 314 28.4 Evidence for LAMPOON-Assisted TMVR 315 28.5 Future Directions 315 28.6 Conclusions 315 References 315 29 Use of Alcohol Septal Reduction Therapy to Facilitate Transcatheter Mitral Valve Replacement 317Marvin H. Eng, Tiberio Frisoli, Dee Dee Wang, James C. Lee, Pedro A. Villablanca Spinetto, Janet Wyman, and William W. O’Neill 29.1 Introduction 317 29.2 Technique 319 29.3 Safety 321 29.4 Efficacy 321 29.5 Conclusion 323 References 323 30 Direct Transatrial Approach with Resection of the Anterior Mitral Leaflet to Prevent Outflow TractObstruction 325Fabien Praz and Isaac George 30.1 Introduction 325 30.2 Advantages of the Direct Transatrial Access 325 30.3 Patients Selection and THV Sizing 326 30.3.1 Mitral Annulus Sizing 326 30.3.2 Assessment of the Risk of LVOTO Using Valve Simulation 326 30.4 Implantation Techniques 328 30.4.1 First-in-Human and Early Experience 328 30.4.2 Strategies to Prevent Paravalvular Leakage 329 30.5 Surgical Access 329 30.6 Early Outcomes Data 330 30.7 Conclusions 331 References 331 31 Transcatheter Closure of Mitral Paravalvular Leak 333Tilak K. R. Pasala, Vladimir Jelnin, and Carlos E. Ruiz 31.1 Introduction 333 31.2 Prevalence and Clinical Presentation 333 31.3 Assessment of Mitral PVL 334 31.3.1 Grading of Severity 334 31.3.2 Complexity of Mitral PVL 334 31.3.3 Adjunctive Imaging 334 31.4 Timing of Intervention 335 31.5 Preplanning 336 31.5.1 Location 336 31.5.2 Virtual Planning 337 31.6 Devices Used for PVL Closure 338 31.6.1 Transcatheter Procedure 338 31.6.2 Procedural Guidance 340 31.6.3 Access 340 31.6.4 Procedural Techniques 341 31.6.4.1 Crossing the PVLs 341 31.6.4.2 Catheter and Device Delivery 343 31.6.4.3 Device Deployment 344 31.6.4.4 Hopscotch Technique 345 31.7 Procedural Complications 345 31.8 Follow-Up 346 31.9 Future 346 31.10 Conclusion 346 Disclosures 346 References 346 32 Management of Iatrogenic Interatrial Septal Defect—To Close or not to Close? 349Christina Tan and James M. McCabe 32.1 Introduction 349 32.2 Hemodynamics and iASDs 349 32.3 Incidence of Persistent Iatrogenic Atrial Septal Defects 350 32.4 Evaluation of Iatrogenic Atrial Septal Defect 351 32.5 Closure 352 32.6 ASD Closure Procedure 352 32.7 Management 353 References 355 33 Antithrombotic Therapy in Transcatheter Mitral Valve Intervention 359Yuefeng Chen and Ron Waksman 33.1 Introduction 359 33.2 MitraClip System 359 33.2.1 Before the Procedure 359 33.2.2 During the Procedure 360 33.2.3 After the Procedure 361 33.2.4 Thromboembolic and Bleeding Risk 361 33.3 Transcatheter Mitral Valve Replacement 362 33.3.1 Before the Procedure 362 33.3.2 During the Procedure 362 33.3.3 After the Procedure 362 33.3.4 Thromboembolic and Bleeding Risk 363 33.4 Patients with Atrial Fibrillation 365 33.5 Antithrombotic Therapy for Other Mitral Valve Interventions 365 33.6 Conclusions 365 References 366 Index 371

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