Respiratory medicine Books
John Wiley and Sons Ltd Respiratory Illness in Children
Book SynopsisThis book has become the standard reference text on respiratory diseases in children. It has been extensively revised and updated to encompass the latest developments, and there are now specific chapters on obstructive sleep apnoea and the lung in HIV infection. The biggest revisions to existing chapters are in those on growth and development, respiratory noises, cough and pulmonary consequences of inhalation. The clinical approach in this book is strongly based on an understanding of epidemiology, pathophysiology and increasingly, molecular biology. This fourth edtition brings a stronger theoretical basis to the clinical practice that has been one of the strengths of previous edtitions.Table of Contents1: Lung Growth and Development;. 2: Neonatal Respiratory Disorders;. 3: Epidemiology of Acute Respiratory Infections;. 4: Clinical Patterns of Acute Respiratory Infection;. 5: Respiratory Noises;. 6: Asthma - Pathogenesis, Pathophysiology and Epidemiology;. 7: Asthma - Clinical Patterns and Management;. 8: Cough;. 9: Suppurative Lung Disease;. 10: Cystic Fibrosis;. 11: Pulmonary Complications of Inhalation;. 12: Tuberculosis in Childhood;. 13: Lung Defences and Infection in the Compromised Host;. 14: The Lung and HIV Infection;. 15: Miscellaneous Lung Diseases;. 16: Obstructive Sleep Apnoea;. 17: Congenital Malformations of the Bronchi, Lungs, Diaphragm and Rib Cage;. 18: Tumours of the Chest Wall, Mediastinum and Lungs;. Appendix;. Index
£141.26
Elsevier Health Sciences Cardiorespiratory Physiotherapy Adults and
Book SynopsisTrade ReviewNow in its fourth edition this text is a must for all physiotherapy students. The chapters are well laid out, and all of the information is explained in an easily understandable way. This new edition provides the most up to date information for clinical practice from paediatrics through to the elderly. Chapter six is particularly useful, it provides the reader with case studies and then works through a logical way of problem solving along with introducing the reader to specific outcome measures. All in all a must have text!!!! - Laura Culpan, Physiotherapy Student, University of Bradford This book is a must have for respiratory learning as it is clear and concise and contains both adults and paediatric care. The clear diagrams make it easier to learn and the chapters cover core subjects for example assessments, techniques, paediatrics, ventilation and many more. Throughout the authors have made small summary physio points which will be useful when revising for a particular topic. The authors have also used flow charts and pictures to put across some of the information which is very useful for visual learners. I would very much recommend this book as it contains all of the information needed for respiratory at university and during your career. - Charlotte Barrett, Physiotherapy Student, Cardiff University, UK. Overall this is a good all-round, evidence based resource to use whilst studying or if newly qualified that covers all the main aspects of respiratory and cardiac physiotherapy. It is a great place to start when writing case studies in this field. This book is structured in the familiar style that we have come to know Elsevier for: a logical and clear design that is well laid out with the text presented in a variety of formats and supported with photographs, drawings and diagrams. The sections covering surgery, again provide good information for the student, particularly things like commonly used drugs and side effects, terminology and common procedures that are likely to be encountered. Finally, there are a number of handy images stored online that can be used in your presentations but perhaps this facility would have been better with a few more resources available, such as quizzes or tests to assess knowledge. - Linda Wilkinson, Physiotherapy Student, University of Southampton, UK. As a 1st year physiotherapy student, I've been able to use this book to understand the pathophysiology of cardiorespiratory problems as well as their clinical management. It's also well structured, beginning with the assessment of a cardiorespiratory patient and covering assessment tests and techniques and their interpretation. I also like that it has separate sections for paediatrics and adults and also has a good overview of types of surgery. I feel that this book is not only useful to me now but will be essential when I go on placement, as a reference to clarify and build on my day-to-day learning. I would recommend this text to anyone looking for a good overall cardiorespiratory text. - Mayuri Butchart, Physiotherapy Student, King's College London, UK. "I found this text book useful, informative and a great aid to my first practice placement." Ms N.L Benson, 2nd Year Physiotherapy Student, University of Central LancashireTable of ContentsForeword About The Editors Preface Acknowledgements Contributors 1 ANATOMY AND PHYSIOLOGY OF THE RESPIRATORY SYSTEM Mandy Jones, Alex Harvey, Eleanor Main 2 CLINICAL ASSESSMENT Adults Amanda Thomas, Lyndal J Maxwell Infant and Child Eleanor Main The Acutely Ill or Deteriorating Patient Sarah Keilty 3 THORACIC IMAGING Adults Conor D Collins, Susan J Copley Paediatrics Joy L Barber, Christopher D George 4 CARDIAC AND CARDIOVASCULAR DISEASES Andrew D Hirschhorn, Sean F Mungovan, David A B Richards 5 RESPIRATORY DISEASES Anne E Holland, Jennifer A Alison With a contribution from Alex Harvey and Mandy Jones 6 OUTCOME MEASUREMENT IN CARDIORESPIRATORY PHYSIOTHERAPY PRACTICE Selina M Parry, Linda Denehy With Contributions from Claire E Baldwin, Bronwen Connolly, Elizabeth H Skinner, Sally J Singh, Sarah Rand, Craig A Williams 7 PHYSIOTHERAPY INTERVENTIONS Eleanor Main With contributions from Sue Berney, Linda Denehy, Michelle Chatwin, Mark R Elkins, Daniel Flunt, Amanda J Piper, Annemarie L Lee, Bredge Mccarren, Harriet Shannon, Rosemary Moore, Sarah Rand, Barbara A Webber, Marie T Williams 8 OPTIMIZING ENGAGEMENT AND ADHERENCE WITH THERAPEUTIC INTERVENTIONS Mandy Bryon 9 ADULT INTENSIVE CARE Jennifer Paratz, George Ntoumenopoulos, Alice Y M Jones, Claire Fitzgerald 10 PAEDIATRIC INTENSIVE CARE Paediatric Mechanical Support Stewart Reid, Mark J Peters Physiotherapy Management of Ventilated Infants and Children Eleanor Main, Alicia J Spittle 11 CARDIOTHORACIC SURGERY FOR ADULTS Doa El-Ansary, Julie C Reeve, Sulakshana, Balachandran, Michelle Mulligan, Linda Denehy 12 PHYSICAL ACTIVITY AND REHABILITATION Physical Activity and Physical Fitness in Health and Disease Chris Burtin, Vasileios Andrianopoulos, Martijn A Spruit Pulmonary Rehabilitation Katy Mitchell, Fabio Pitta, Anne E Holland, Annemarie L Lee, Linda Denehy Cardiac Rehabilitation Julie Redfern, Jennifer Jones 13 CARDIORESPIRATORY MANAGEMENT OF SPECIAL POPULATIONS Linda Denehy, Eleanor Main With contributions from Sarah Smailes, Anita Plaza, Jennifer Paratz, Leanne Williams, Claire Bradley, Jacqueline L Luke, Jacqueline Ross, Brooke Wadsworth, Kate J Hayes, Prue E Munro, Paul Aurora, Helena Van Aswegen, Craig A Williams, Sarah Rand, Catherine L Granger, Sue Berney, Amy Nordon-Craft, Linda Denehy APPENDIX - NORMAL VALUES, CONVERSION TABLE AND ABBREVIATIONS Index
£46.54
Elsevier Health Sciences Recognizing and Treating Breathing Disorders
Book SynopsisDisordered breathing patterns may be a symptom or a cause of frequently undiagnosed health problems. This book is intended to help practitioners understand the causes and effects of disordered breathing and to provide strategies and protocols to help restore normal function.Trade Review"...this far-reaching book covers everything one would wish to learn about breathing pattern disorders - I feel it is an essential source of reference and information to all health professionals working in this area...I would urge everyone interested in the subject to place an order..." Anne Pitman MCSP SRP, Manual Therapy, October 2002 "The whole book is well illustrated and referenced, provides practical case examples and sensible cautions..I cannot think of anything they have left out. Ashley Conway. Journal of Holistic Healthcare: Volume 4 Issue 4 November 2007 Patients with common psychological dysfunction including anxiety, low mood and depression, sleep disorder, chronic low energy syndromes etc., all can respond well when the breath cycle is identified and adapted by cognitive processes. This text is the most comprehensive of its kind and the clinical application of the content so broadly based it deserves a wide readership. Donald Scott, Osteopath, UK This is an extremely well-detailed book and I love how it explores all areas of breathing i.e. the psychological, emotional and physical elements of the process. Eva Au Zveglic, Specialised Respiratory Physiotherapist, UK This book will appeal to anyone with an interest in breathing from whatever discipline they belong to. Anne Pitman, Physiotherapy, Devonshire Place, London, UK As the current title suggests, I feel the book appropriately covers multidisciplinary management strategies of BPD which is an extremely important aim given that the disorder is so complex with multiple aetiologies and no single assessment or treatment tool. Kate Bazin. Physiotherapist, UK Breathing is an overlooked part of human function. We need more information about breathing as it is such an important prerequisite for the normal functioning of so many other body systems. Ken Crenshaw, Head Athletic Trainer of the Arizona Diamondbacks Baseball Team, USA As clinical practitioners we must always be aware of causation, maintaining and exacerbating factors. Abnormal breathing has the ability to be all three of these. T. Hewetson, Lecturer in Osteopathy, Oxford, UK This is not a perfect all-encompassing textbook.That was not its purpose. As a catalyst for stimulating further exploration and for use as a reference in clinical work of wide-ranging paradigms it succeeds admirably. David Propert, British School of Osteopathy, UK, International Journal of Osteopathic Medicine (August 2014) Table of Contents1. What are Breathing Pattern Disorders? - Leon Chaitow, Dinah Bradley, Chris Gilbert 2.1 Dynamic Neuromuscular Stabilization - Developmental Kinesiology: breathing stereotypes and postural-locomotion function - Pavel Kolar, Alena Kobesova, Petra Valouchova, Petr Bitnar 2.2. The structure and function of breathing - Leon Chaitow, Dinah Bradley, Chris Gilbert 2.3. Nasal influences on breathing - Jim Bartley 3. Patterns of breathing dysfunction in hyperventilation and breathing pattern disorders - Dinah Bradley 4. Biochemical aspects of breathing - Chris Gilbert (notes on food sensitivities and nutrition: Leon Chaitow) 5. Interaction of psychological and emotional variables with breathing dysfunction - Chris Gilbert 6.1. Dynamic Neuromuscular Stabilization: Assessment methods - Pavel Kolar, Alena Kobesova, Petra Valouchova, Petr Bitnar 6.2. Osteopathic assessment of structural changes related to BPD - Leon Chaitow 6.3. Physiotherapy Assessment Approaches - Dinah Bradley 6.4 Psychological assessment of breathing problems - Chris Gilbert 6.5 Questionnaires and Manual Methods for Assessing Breathing Dysfunction - Rosalba Courtney, Jan van Dixhoorn 6.6 Capnography Assessment - Laurie McLaughlin 7.1a Indirect approaches to breathing regulation - Jan van Dixhoorn 7.1b Dynamic Neuromuscular Stabilization: Treatment methods - Pavel Kolar, Alena Kobesova, Petra Valouchova, Petr Bitnar 7.2 Osteopathic treatment of thoracic and respiratory dysfunction - Leon Chaitow 7.3 Physiotherapy in rehabilitation of breathing pattern disorders - Dinah Bradley 7.4 Physiotherapy in rehabilitation of breathing pattern disorders - Chris Gilbert 7.5 Speech and singing - Eva au Zveglic 7.6 Breathing Pattern Disorders and the Athlete - Tania Clifton Smith 7.7 Capnography in treatment of BPD - Laurie McLaughlin 8.1 Breathing patterns in longstanding pain disorders: A somatocognitive approach to evaluation and therapy - G. Haugstad, T. Haugstad 8.2 Buteyko breathing method - Rosalba Courtney 8.3 Feldenkrais® and Breathing - John C. Hannon 8.4 Pilates in the rehabilitation of breathing disorders - Warrick McNeill, Suzanne Scott 8.5 Tai chi Qigong and breathing - Aileen Chan 8.6 A review of the use of yoga in breathing disorders - Shirley Telles, Nilkamal Singh 9 Self-help approaches - Leon Chaitow, Dinah Bradley, Chris Gilbert
£40.49
Elsevier Health Sciences Essentials of Dental Radiography and Radiology
Book SynopsisTable of ContentsPart 1 Introduction 1 The radiographic image Part 2 Radiation physics, equipment and radiation protection 2 The production, properties and interactions of X-rays 3 Dental X-ray generating equipment 4 Image receptors 5 Imaging processing 6 Radiation dose, dosimetry and dose limitation 7 The biological effects associated with X-rays, risk and practical radiation protection Part 3 Radiography 8 Dental radiography - general patient considerations including control of infection 9 Periapical radiography 10 Bitewing radiography 11 Occlusal radiography 12 Oblique lateral radiography 13 Skull and maxillofacial radiography 14 Cephalometric radiography 15 Tomography and panoramic radiography 16 Cone beam computed tomography (CBCT) 17 The quality of radiographic images and quality assurance 18 Alternative and specialized imaging modalities Part 4 Radiology 19 Introduction to radiological interpretation 20 Dental caries and the assessment of restorations 21 The periapical tissues 22 The periodontal tissues and periodontal disease 23 Implant assessment 24 Developmental abnormalities 25 Radiological differential diagnosis - describing a lesion 26 Differential diagnosis of radiolucent lesions of the jaws 27 Differential diagnosis of lesions of variable radiopacity in the jaws 28 Bone diseases of radiological importance 29 Trauma to the teeth and facial skeleton 30 The temporomandibular joint 31 The maxillary antra 32 The salivary glands Bibliography and suggested reading Index
£51.29
Elsevier Health Sciences Chest XRay Made Easy
Book SynopsisTable of ContentsHow to look at a chest X-ray Localizing lesions The CT scan The white lung field The black lung field The abnormal hilum The abnormal heart shadow The widened mediastinum Abnormal ribs Abnormal soft tissues The sick patient The hidden abnormality The chest x-ray quiz
£28.49
John Wiley & Sons A Long Way from Home The Tuberculosis Epidemic
Book SynopsisFocusing on patients' experiences and the programmes set up to deal with the tuberculosis epidemic experienced by the Inuit in the mid-20th century, this study is based on recollections of patients and interviews with participants in the government programmes.
£26.99
Lippincott Williams and Wilkins Pulmonary Physiology and Pathophysiology
Book SynopsisThe Second Edition of Pulmonary Physiology and Pathophysiology presents normal and abnormal pulmonary function in the same case-based format that has made the first edition a favorite among students. Each chapter begins with a clinical case study of diseases typically seen by practitioners. The cases are followed by a discussion and breakdown of the physiology, pathophysiology, anatomy, pharmacology, and pathology for each disease, and a question-and-answer section. This edition has an infectious diseases chapter, updates on asthma pathogenesis and bronchodilators, and user-friendly features such as chapter openers, chapter outlines, key points summary boxes, and board-formatted questions and answers.
£51.02
MP-FAD F.A. Davis Respiratory Disease a Case Study Approach to
Book SynopsisNow edited by a pulmonologist, this third edition is one of the best written texts for students learning to understand the assessment and treatment of patients with respiratory disease. Each chapter begins with a background of selected disorders, followed by a case study with questions and answers designed to stimulate critical thinking skills.Table of Contents CHAPTER 1 Introduction to Patient Assessment Robert L. Wilkins, PhD, RRT, FAARC Philip M. Gold, MD, MACP, FCCP CHAPTER 2 Introduction to Respiratory Failure Robert L. Wilkins, PhD, RRT, FAARC James R. Dexter, MD, FACP, FCCP CHAPTER 3 Asthma Robert L. Wilkins, PhD, RRT, FAARC Philip M. Gold, MD, MACP, FCCP CHAPTER 4 Chronic Obstructive Pulmonary Disease Robert L. Wilkins, PhD, RRT, FAARC Philip M. Gold, MD, MACP, FCCP CHAPTER 5 Cystic Fibrosis N. Lennard Specht, MD CHAPTER 6 Hemodynamic Monitoring and Shock Robert L. Wilkins, PhD, RRT, FAARC James R. Dexter, MD, FACP, FCCP CHAPTER 7 Pulmonary Thromboembolic Disease James R. Dexter, MD, FACP, FCCP CHAPTER 8 Heart Failure Arthur B. Marshak, MS, RRT, RPFT George H. Hicks, MS, RRT CHAPTER 9 Smoke Inhalation Injury and Burns George H. Hicks, MS, RRT Carl Eckrode, MPH, RRT CHAPTER 10 Near Drowning William F. Galvin, MSEd, RRT, CPFT, FAARC CHAPTER 11 Acute Respiratory Distress Syndrome Robert L. Wilkins, PhD, RRT, FAARC James R. Dexter, MD, FACP, FCCP CHAPTER 12 Chest Trauma George H. Hicks, MS, RRT Carl A. Eckrode, MPH, RRT CHAPTER 13 Postoperative Atelectasis Thomas P. Malinowski, BS, RRT, FAARC CHAPTER 14 Interstitial Lung Disease N. Lennard Specht, MD, FACP CHAPTER 15 Neuromuscular Diseases N. Lennard Specht, MD, FACP Rebekah Bartos, MSN, FNP CHAPTER 16 Bacterial Pneumonia Robert L. Wilkins, PhD, RRT, FAARC James R. Dexter, MD, FACP, FCCP CHAPTER 17 Pneumonia in the Immunocompromised Patient Philip M. Gold, MD, MACP, FCCP N. Lennard Specht, MD, FACP CHAPTER 18 Sleep Disordered Breathing Enrique Gil, MD, FCCP CHAPTER 19 Tuberculosis James R. Dexter, MD, FACP, FCCP Robert L. Wilkins, PhD, RRT, FAARC CHAPTER 20 Lung Cancer Gregory A.B. Cheek, MD, FCCP, MSPH APPENDIX A Normal Laboratory Values APPENDIX B GOLD Standards for Diagnosing and Treating Patients with COPD APPENDIX C Websites Useful for Learning Information About the Diagnosis and Treatment of Lung Disease Index
£62.10
MP-FAD F.A. Davis Laboratory Exercises for Competency in Repiratory
Book SynopsisRely on this best-selling laboratory manual to provide the hands-on practice you need to confidently perform the most common to complex respiratory procedures for class and clinical. Step-by-step instructions with detailed diagrams and illustrations seamlessly guide you through every procedure.Table of Contents Laboratory and Clinical Safety Communication and Cultural Diversity in Health Care Infection Control Sterilization and Disinfection Medical Record Patient Assessment: Basic Skills Vital Signs Patient Assessment: Advanced Skills Bedside Assessment of Pulmonary Mechanics Oxygen Supply Systems Oxygen Analysis Oxygen Therapy Administration Humidity Devices Aerosol Generators Cardiopulmonary Pharmacology Review Aerosol and Medication Therapy Hyperinflation Therapy Techniques Bronchial Hygiene: Chest Physiotherapy Adjunct Techniques for Bronchial Hygiene Manual Resuscitators and Manual Ventilation Pharyngeal Airways Suctioning Endotracheal Intubation Tracheostomy Care Artificial Airway Care and Maintenance Noninvasive Blood Gas Monitoring Arterial Blood Gas Sampling Arterial Blood Gas Analysis and Maintenance Blood Gas Interpretation and Calculations Basic Chest X Ray Interpretation Pulmonary Function Testing Electrocardiography Hemodynamic Monitoring Phlebotomy Intravenous Insertion and Maintenance Chest Tube Drainage Systems Bronchoscopy Assisting Noninvasive Ventilation Pressure Ventilators Continuous Mechanical Ventilation Ventilator Modes Ventilator Initiation Patient Ventilator System Care and Maintenance Discontinuation of Mechanical Ventilation Neonatal/Pediatric Respiratory Care Neonatal/Pediatric Ventilation Respiratory Care in Alternate Settings Appendices Normal and Critical Values, Formulas and Rules of Thumb Glossary
£78.30
MP-FAD F.A. Davis Neonatal and Pediatric Respiratory Care
Book SynopsisGain a solid understanding of neonatal and pediatric diseases as you explore real-world patient experiences with this unique resource. In every chapter, unfolding case studies with full-colour illustrations and photographs enhance your critical-thinking skills, making it easy to connect theory with practice.Table of Contents 1. Making Sense of Caring for Kids: A Different Approach to Respiratory Care I. Fetal Development and Transition to Extrauterine Life 2. Fetal Cardiopulmonary Development 3. Resuscitation of the Newborn During Transition to Extrauterine Life II. Perinatal Lung Diseases and Complication 4. Respiratory Distress Syndrome 5. Apnea of Prematurity and Bronchopulmonary Dysplasia 6. Diseases of Full-term infants III. Common Neonatal Complications 7. Pulmonary Complications 8. Multi-system Complications IV. Congenital Anomalies 9. Abdominal Defects 10. Airway abnormalities 11. Acyanotic Heart Defects 12. Cyanotic Heart Defects V. Pediatric Diseases with Respiratory Implications 13. Asthma 14. Cystic Fibrosis 15. Pediatric Pulmonary Diseases 16. Pediatric Infectious Airway Diseases 17. Neuromuscular Disorders 18. Pediatric Accidents with Pulmonary Involvement 19. Pediatric Neurologic Accidents VI. Ethics and Pediatric Palliative Care 20. Ethics in Perinatal and Pediatric Respiratory Care 21. Palliative and End-of-Life Care Glossary Index
£78.30
Stanford University Press Sars in China
Book SynopsisThis book examines the structure and impact of the SARS epidemic, and its short- and medium-range implications for an interconnected, globalized world. In so doing, it poses a question of the greatest possible significance: Can we learn from SARS before the next pandemic?Trade Review"SARS in China not only makes a significant contribution to China studies but also provides important clues about the state of preparation for global health challenges such as avian flu."—China Review International"This book has lined up a remarkable team of authors to try to answer the question: what can we learn from SARS before the next pandemic? And its value lies in the significant issues that it has highlighted."—The China ReviewTable of ContentsContents Preface vii Contributors xi Introduction: SARS in Social and Historical Context 1 arthur kleinman and james l. watson Part I. The Epidemiological and Public Health Background 1. The Epidemiology of SARS 17 megan murray 2. The Role of the World Health Organization in Combating SARS, Focusing on the Efforts in China 31 alan schnur 3. SARS and China's Health-Care Response: Better to Be Both Red and Expert! 53 joan kaufman Part II. Economic and Political Consequences 4. Is SARS China's Chernobyl or Much Ado About Nothing? 71 tony saich 5. SARS and China's Economy 105 thomas g. rawski 6. SARS in Beijing: The Unraveling of a Cover-Up 122 erik eckholm Part III: Social, Moral, and Psychological Consequences 7. Psychological Responses to SARS in Hong Kong-- Report from the Front Line 133 dominic t. s. lee, m.d., and yung kwok wing, mrcpsych 8. Making Light of the Dark Side: SARS Jokes and Humor in China 148 hong zhang Part IV: Globalization and Cross-Cultural Issues 9. SARS and the Problem of Social Stigma 173 arthur kleinman and sing lee 10. SARS and the Consequences for Globalization 196 james l. watson Notes 205 Index 235
£70.55
Stanford University Press SARS in China
Book SynopsisThis book examines the structure and impact of the SARS epidemic, and its short- and medium-range implications for an interconnected, globalized world. In so doing, it poses a question of the greatest possible significance: Can we learn from SARS before the next pandemic?Trade Review"SARS in China not only makes a significant contribution to China studies but also provides important clues about the state of preparation for global health challenges such as avian flu."—China Review International"This book has lined up a remarkable team of authors to try to answer the question: what can we learn from SARS before the next pandemic? And its value lies in the significant issues that it has highlighted."—The China ReviewTable of ContentsContents Preface vii Contributors xi Introduction: SARS in Social and Historical Context 1 arthur kleinman and james l. watson Part I. The Epidemiological and Public Health Background 1. The Epidemiology of SARS 17 megan murray 2. The Role of the World Health Organization in Combating SARS, Focusing on the Efforts in China 31 alan schnur 3. SARS and China's Health-Care Response: Better to Be Both Red and Expert! 53 joan kaufman Part II. Economic and Political Consequences 4. Is SARS China's Chernobyl or Much Ado About Nothing? 71 tony saich 5. SARS and China's Economy 105 thomas g. rawski 6. SARS in Beijing: The Unraveling of a Cover-Up 122 erik eckholm Part III: Social, Moral, and Psychological Consequences 7. Psychological Responses to SARS in Hong Kong-- Report from the Front Line 133 dominic t. s. lee, m.d., and yung kwok wing, mrcpsych 8. Making Light of the Dark Side: SARS Jokes and Humor in China 148 hong zhang Part IV: Globalization and Cross-Cultural Issues 9. SARS and the Problem of Social Stigma 173 arthur kleinman and sing lee 10. SARS and the Consequences for Globalization 196 james l. watson Notes 205 Index 235
£17.99
Stanford University Press Infectious Change
Book SynopsisTrade Review"In this defining ethnography of China's public health system and its complex relation to epidemics, Katherine Mason brilliantly describes health professionals, their struggles to be effective and ethical, the barriers they face, and how they animate the Chinese public health system as a lived reality. Infectious Change is an impressive contribution to both China studies and to medical anthropology!" -- Arthur Kleinman, Director * Harvard Asia Center *"Meticulously crafted, Infectious Change draws readers into the world of Chinese public health after SARS. Mason documents fundamentally different approaches to epidemic control among global, state, and local practitioners, including management of migratory populations, data collection, and ethics, arguing that global directives often stymie local efforts. This book elucidates why epidemic prevention everywhere must draw on local knowledge and practices." -- Margaret Lock * author of The Alzheimer Conundrum *"Infectious Change brings us for the first time before a hitherto unacknowledged consequence of the 2009 H1N1 crisis, and, at that, in one of the most epidemiologically critical regions of the globe today. It is this invaluable insight that should hold the attention not only of medical anthropologists but also of the wider global health community." -- Christos Lynteris * Medical Anthropology Quarterly *"This is an excellent, thought-provoking book, which will appeal to those with interests in contemporary China, medical anthropology, and histories of health and disease. It yields insights that will illuminate broader debates, such as those that pivot on the challenges inherent in promoting the "global" as a category in health." -- Robert Peckham * Bulletin of the History of Medicine *"Katherine Mason's book is an important contribution to the fields of Chinese studies and anthropology, joining a recent spate of excellent studies using the methods of anthropology to look at the intersections of public health, cultural practices and politics in China...Mason's book reminds us that implementing public health policy is never only about what is technically correct. It is about the cultural values and practices that govern relationships. It is also about understanding the power dynamics of the political system and generating the political will to construct an enabling environment and accountability mechanism to achieve it. In China, the tensions between centre and local are rarely resolved in favour of local and when new criteria for professional advancement are introduced, it results in the type of dysfunction so masterfully described by Mason." -- Joan Kaufman * China Quarterly *"In Infectious Change, Katherine A. Mason provides a captivating analysis of public health in China in the wake of SARS...Infectious Change is an insightful work that would be of interest to scholars of China and global health practitioners while also being accessible to a general academic reader. For China scholars, Mason makes a major contribution to the literature on public health." -- Emilio Dirlikov * Anthropological Quarterly *"Infectious Change presents a rich ethnographic account of how the Tianmai CDC works, how it would like to transform itself, and the barriers to doing so. It will make an excellent addition to courses on the anthropology of China or of global health because of the clarity of its ethnographic account and also because of the questions it opens up."––Elanah Uretsky, Asian MedicinTable of ContentsContents and Abstracts1Introduction chapter abstractThis chapter situates the reader in time and space and lays out the main arguments of the book. The author provides an overview of the recent history of public health in China, and describes the pseudonymous city of Tianmai. The author then suggests that due to key differences between professional responsibility as it is defined in the clinical and public health settings - particularly with regards to the aggregate nature of the public health "client" – a bifurcation of service and governance arose in Tianmai between a "common" being served and local populations being governed. The chapter lays out five "commons" that will be examined in the rest of the book: a civilized immigrant common, a professional common, a transnational scientific common, a global health common, and a global common. It also suggests that the Tianmai case can offer novel insights into the study of global health. 2City of Immigrants chapter abstractThis chapter takes a closer look at the immigrant city of Tianmai, and considers how the modern, cosmopolitan urban paradise that Tianmai's elites were trying to build included some and excluded others. In particular, the chapter examines the relationship – or lack thereof – between Tianmai's public health professionals and the city's enormous "floating population" of rural-to-urban migrants. The author shows how her interlocutors – former migrants themselves – refused to engage with migrant individuals, and actively maintained personal, moral, and professional boundaries between themselves and the floating population. This effectively divulged public health professionals of responsibility for the majority of the people who lived in their city and established them as "biological non-citizens" who had to be governed but could not be served. In doing this public health professionals worked to serve a civilized immigrant common of modern urban subjects that did not include the floating population. 3Relationships, Trust, and Truths chapter abstractThis chapter illustrates how the power to implement any given public health initiative in China was located within the webs of guanxi, or personal relationships, that public health professionals spun anew at the beginning of each project. Drawing on rich ethnographic description, the chapter takes the reader into the banqueting and other entertainment rituals that public health professionals engaged in almost daily in order to create and maintain these networks of reciprocal obligation and personalistic trust. The author then examines how a group of young, highly educated post-SARS reformers attempted to rid the public health system of guanxi, which they regarded as anti-scientific and akin to corruption. These reformers hoped to build a more transparent and reliable system of disease reporting and governance by establishing a professional common grounded in professionalized trust. 4Scientific Imaginaries chapter abstractThis chapter critically examines public health research and science in Tianmai. The author explores the efforts of Chinese public health professionals to advance their careers through scientific research, and discusses how in the wake of SARS, Chinese public health institutions dramatically increased their investments in scientific research – rendering publishable research a major focus of local public health work. Newly hired young people labored to produce the "quality" and "true" data that they associated with good science. They hoped that doing so would give them a chance to "develop themselves" as members of transnational scientific common, and to escape a local moral world that they felt was dominated by mimicry, deception, and instability. The chapter suggests that their approach to research provides a mirror through which public health researchers in other contexts could critically examine their own ethical practices, raising new questions about global research ethics. 5Pandemic Betrayals chapter abstractThis chapter provides an ethnographically rich eyewitness account of Tianmai's response to the 2009 H1N1 influenza pandemic, describing how public health professionals in Tianmai drew upon the lessons of SARS to mount what they thought would be an internationally lauded response to H1N1. In attempting to prove their pandemic preparedness capabilities and ensure a place among the global scientific elite, however, Tianmai's public health professionals instead found that their full admittance into a global health common and a global common remained elusive. The chapter discusses the professionals' difficulties in escaping their perceived status as a source, rather than a victim, of dangerous viruses; their use of disease control tactics that were portrayed abroad as excessive and unsophisticated; and their disappointment with the failure of their leaders and guanxi partners to act in the professional fashion that they had been trying to promote since SARS. 6Conclusion chapter abstractThe concluding chapter returns to the broader question of what professional responsibility can or should mean in public health and beyond, and asks how public health professionals in China could work to reconcile the "common" with the "population," and population needs with individual needs. The author uses the case of HIV/AIDS to examine the ways in which some public health professionals in Tianmai were experimenting with alternative interpretations of public health that broadened the boundaries of the common to allow in otherwise maligned groups, including rural migrants, gay men, and sex workers. The book ends by considering the implications of this ethnography for the study of public health – both local and global – more broadly.
£67.15
Stanford University Press Infectious Change
Book SynopsisTrade Review"In this defining ethnography of China's public health system and its complex relation to epidemics, Katherine Mason brilliantly describes health professionals, their struggles to be effective and ethical, the barriers they face, and how they animate the Chinese public health system as a lived reality. Infectious Change is an impressive contribution to both China studies and to medical anthropology!" -- Arthur Kleinman, Director * Harvard Asia Center *"Meticulously crafted, Infectious Change draws readers into the world of Chinese public health after SARS. Mason documents fundamentally different approaches to epidemic control among global, state, and local practitioners, including management of migratory populations, data collection, and ethics, arguing that global directives often stymie local efforts. This book elucidates why epidemic prevention everywhere must draw on local knowledge and practices." -- Margaret Lock * author of The Alzheimer Conundrum *"Infectious Change brings us for the first time before a hitherto unacknowledged consequence of the 2009 H1N1 crisis, and, at that, in one of the most epidemiologically critical regions of the globe today. It is this invaluable insight that should hold the attention not only of medical anthropologists but also of the wider global health community." -- Christos Lynteris * Medical Anthropology Quarterly *"This is an excellent, thought-provoking book, which will appeal to those with interests in contemporary China, medical anthropology, and histories of health and disease. It yields insights that will illuminate broader debates, such as those that pivot on the challenges inherent in promoting the "global" as a category in health." -- Robert Peckham * Bulletin of the History of Medicine *"Katherine Mason's book is an important contribution to the fields of Chinese studies and anthropology, joining a recent spate of excellent studies using the methods of anthropology to look at the intersections of public health, cultural practices and politics in China...Mason's book reminds us that implementing public health policy is never only about what is technically correct. It is about the cultural values and practices that govern relationships. It is also about understanding the power dynamics of the political system and generating the political will to construct an enabling environment and accountability mechanism to achieve it. In China, the tensions between centre and local are rarely resolved in favour of local and when new criteria for professional advancement are introduced, it results in the type of dysfunction so masterfully described by Mason." -- Joan Kaufman * China Quarterly *"In Infectious Change, Katherine A. Mason provides a captivating analysis of public health in China in the wake of SARS...Infectious Change is an insightful work that would be of interest to scholars of China and global health practitioners while also being accessible to a general academic reader. For China scholars, Mason makes a major contribution to the literature on public health." -- Emilio Dirlikov * Anthropological Quarterly *"Infectious Change presents a rich ethnographic account of how the Tianmai CDC works, how it would like to transform itself, and the barriers to doing so. It will make an excellent addition to courses on the anthropology of China or of global health because of the clarity of its ethnographic account and also because of the questions it opens up."––Elanah Uretsky, Asian MedicinTable of ContentsContents and Abstracts1Introduction chapter abstractThis chapter situates the reader in time and space and lays out the main arguments of the book. The author provides an overview of the recent history of public health in China, and describes the pseudonymous city of Tianmai. The author then suggests that due to key differences between professional responsibility as it is defined in the clinical and public health settings - particularly with regards to the aggregate nature of the public health "client" – a bifurcation of service and governance arose in Tianmai between a "common" being served and local populations being governed. The chapter lays out five "commons" that will be examined in the rest of the book: a civilized immigrant common, a professional common, a transnational scientific common, a global health common, and a global common. It also suggests that the Tianmai case can offer novel insights into the study of global health. 2City of Immigrants chapter abstractThis chapter takes a closer look at the immigrant city of Tianmai, and considers how the modern, cosmopolitan urban paradise that Tianmai's elites were trying to build included some and excluded others. In particular, the chapter examines the relationship – or lack thereof – between Tianmai's public health professionals and the city's enormous "floating population" of rural-to-urban migrants. The author shows how her interlocutors – former migrants themselves – refused to engage with migrant individuals, and actively maintained personal, moral, and professional boundaries between themselves and the floating population. This effectively divulged public health professionals of responsibility for the majority of the people who lived in their city and established them as "biological non-citizens" who had to be governed but could not be served. In doing this public health professionals worked to serve a civilized immigrant common of modern urban subjects that did not include the floating population. 3Relationships, Trust, and Truths chapter abstractThis chapter illustrates how the power to implement any given public health initiative in China was located within the webs of guanxi, or personal relationships, that public health professionals spun anew at the beginning of each project. Drawing on rich ethnographic description, the chapter takes the reader into the banqueting and other entertainment rituals that public health professionals engaged in almost daily in order to create and maintain these networks of reciprocal obligation and personalistic trust. The author then examines how a group of young, highly educated post-SARS reformers attempted to rid the public health system of guanxi, which they regarded as anti-scientific and akin to corruption. These reformers hoped to build a more transparent and reliable system of disease reporting and governance by establishing a professional common grounded in professionalized trust. 4Scientific Imaginaries chapter abstractThis chapter critically examines public health research and science in Tianmai. The author explores the efforts of Chinese public health professionals to advance their careers through scientific research, and discusses how in the wake of SARS, Chinese public health institutions dramatically increased their investments in scientific research – rendering publishable research a major focus of local public health work. Newly hired young people labored to produce the "quality" and "true" data that they associated with good science. They hoped that doing so would give them a chance to "develop themselves" as members of transnational scientific common, and to escape a local moral world that they felt was dominated by mimicry, deception, and instability. The chapter suggests that their approach to research provides a mirror through which public health researchers in other contexts could critically examine their own ethical practices, raising new questions about global research ethics. 5Pandemic Betrayals chapter abstractThis chapter provides an ethnographically rich eyewitness account of Tianmai's response to the 2009 H1N1 influenza pandemic, describing how public health professionals in Tianmai drew upon the lessons of SARS to mount what they thought would be an internationally lauded response to H1N1. In attempting to prove their pandemic preparedness capabilities and ensure a place among the global scientific elite, however, Tianmai's public health professionals instead found that their full admittance into a global health common and a global common remained elusive. The chapter discusses the professionals' difficulties in escaping their perceived status as a source, rather than a victim, of dangerous viruses; their use of disease control tactics that were portrayed abroad as excessive and unsophisticated; and their disappointment with the failure of their leaders and guanxi partners to act in the professional fashion that they had been trying to promote since SARS. 6Conclusion chapter abstractThe concluding chapter returns to the broader question of what professional responsibility can or should mean in public health and beyond, and asks how public health professionals in China could work to reconcile the "common" with the "population," and population needs with individual needs. The author uses the case of HIV/AIDS to examine the ways in which some public health professionals in Tianmai were experimenting with alternative interpretations of public health that broadened the boundaries of the common to allow in otherwise maligned groups, including rural migrants, gay men, and sex workers. The book ends by considering the implications of this ethnography for the study of public health – both local and global – more broadly.
£17.09
Cengage Learning, Inc Geriatric Respiratory Care
Book SynopsisA text for gerontology and geriatrics that focuses entirely on respiratory care. It provides a unique insight into the medical and psychosocial problems of the geriatric population. The text covers the various theories of aging and the issues of aging from the sociological perspective.Trade ReviewGerontology:The Study of Aging.Psychosocial Issues.Anatomic and Physiologic Changes in Later Life.Chronic Diseases of the Elderly.Pharmacology.Acute Disease of the Elderly.Long Term Care.The End of Life.Table of ContentsGerontology:The Study of Aging.Psychosocial Issues.Anatomic and Physiologic Changes in Later Life.Chronic Diseases of the Elderly.Pharmacology.Acute Disease of the Elderly.Long Term Care.The End of Life.
£126.00
University of Chicago Press On Asthma Volume 1 Medical Works of Moses
Book SynopsisMoses Maimonides (1135-1204) remains one of the most celebrated rabbis in the history of Judaism, having written extensively on law, philosophy, religion and medicine. This text, the first volume of Maimonides' complete medical writings, is a complete regimen of health for an unnamed patient.
£72.00
Brigham Young University Press On Asthma Volume 2 Critical Editions of Hebrew
Book SynopsisOffers Gerrit Bos' critical editions of all three surviving medieval Hebrew translations of Maimonides' work: one allegedly prepared by the fourteenth-century physician Samuel Benveniste; a second by Joshua Shatibi from Jativa between the years 1379 and 1390; and a third by an anonymous translator, possibly in the thirteenth century.
£105.00
Taylor & Francis Inc Obstructive Sleep Apnea
Book SynopsisMore than 18 million Americans have Obstructive Sleep Apnea (OSA), but more than 90% of cases still remain undiagnosed. This source offers a thorough review of key considerations in the identification and treatment of OSA, and discusses issues often unaddressed in other publications on the topic, such as gender, age, drug interactions, and associated conditions to supply the clinician with best practices, expert recommendations, and clear-cut tables and guidelines for the care of patients with this disorder.Table of ContentsHistory and Physical Examination. Screening and Case Finding. PSG and Cardiorespiratory Monitoring. Upper Airway Imaging. Alertness and Sleepiness Assessment. CPAP. Bilevel Pressure and Adaptive Servo-Ventilation for Obstructive and Complex Sleep Apnea. Auto- Positive Airway Pressure. Critical Factors in Positive Pressure Therapy. Noninvasive Positive Ventilation. Upper Airway Surgery in the Adult. Oral Appliances. Adjunctive and Alternative Therapies. Gender Differences. Obstructive Sleep Apnea in Children. Obstructive Sleep Apnea in the Elderly. Medication Effects. Snoring and Upper Airway Resistance Syndrome (UARS). Central Sleep Apnea. Other Respiratory Conditions and Disorders. Other Sleep Disorders.Neurologic Disorders. Medical Disorders. Legal Implications of Obstructive Sleep Apnea. A Concluding Note and Future Directions
£228.00
John Wiley and Sons Ltd Manual of Neonatal Respiratory Care
Book SynopsisThe first reports of the successful use of mechanical ventilation to treat respiratory disorders in the neonate were published in the 1960s.Trade Review"Four Stars" "This is a complete overview of every aspect of respiratory interventions and assessments. I am very impressed with the chapters and information available of the new state-of-the-art ventilators and the wider ranges of modalities that are extensively covered. This information may help clinicans narrow the options when faced with so many choices and options in ventilaor management. The binding is also convenient and allows the pages to lay flat. The list of abbreviations is complete. Not only is there a detailed table of contents, but index as well. "I have had 17 years of neonatal experience and I find a great need for a current, updated manual to have as a reference in a Level III NICU. I appreciate involvement that respiratory care practitioners had with the physicians in the development of this manual. These contributors are widely respected and experts in the field." Doody’s Review Service "The manual with its large font size, simple line diagrams and easy to read text makes it a very readable book. It is strongly recommended for residents, consultants and nurses providing active neonatal respiratory support." Indian Paediatrics "The extent of coverage, easy readability, and superb organization in conjunction with the plethora of practical pearls make it worthwhile having access to this book in a bed-side library. For a price tag of $89.00, it is simply a great bargain." Journal of Perinatology "This is a complete book that covers what you need when taking care of critical infants with respiratory disease. It enhances the collaboration of the health care team in the NICU and promotes the team’s efficiency in managing these ill infants. By thoroughly understanding and applying the information in this volume, the survival rate in the NICU may be increased and the complication rate will decrease. Journal of Pediatric NursingTable of ContentsForeword. Alan H. Jobe. Preface. Abbreviations Used in This Book. Section I. Lung Development and Normal Pulmonary Physiology. Chapter 1. Development of the Respiratory System. (Vinod K. Bhutani). Chapter 2. Spontaneous Breathing. (Emidio M. Sivieri, Vinod K. Bhutani). Chapter 3. Pulmonary Gas Exchange. (Vinod K. Bhutani). Chapter 4. Pulmonary Mechanics. (Emidio M. Sivieri, Vinod K. Bhutani). Section II. Assessment of Cardiopulmonary Function. Chapter 5. Clinical Examination. (N.R.C. Roberton). Chapter 6. Radiography. (Lawrence R. Kuhns). Chapter 7. Interpretation of Blood Gases. (David J. Durand). Chapter 8. Neonatal Graphic Monitoring. (Joanne J. Nicks). Chapter 9. Continuous Monitoring Techniques. (Christian F. Poets, David P. Southall). Chapter 10. Echocardiography. (Jonathan P. Wyllie). Section III. Neonatal Respiratory Failure. Chapter 11. Indications for Mechanical Ventilation. (Anne Greenough, Anthony D. Milner). Chapter 12. Mechanisms of Respiratory Failure. (Anne Greenough, Anthony D. Milner). Chapter 13. Tissue Hypoxia. (Anne Greenough, Anthony D. Milner). Chapter 14. Neonatal Resuscitation. (Janet M. Rennie). Section IV. Mechanical Ventilation. Chapter 15. Basic Principles of Mechanical Ventilation. (Waldemar A. Carlo, Namasivayam Ambalavanan, Robert L. Chatburn). Chapter 16. Classification of Mechanical Ventilation Devices. (Waldemar A. Carlo, Namasivayam Ambalavanan, Robert L. Chatburn). Chapter 17 Ventilator Parameters. (Waldemar A. Carlo, Namasivayam Ambalavanan, Robert L. Chatburn). Section V. Conventional Ventilation. Chapter 18. Continuous Positive Airway Pressure. (Colin J. Morley). Chapter 19. Intermittent Mandatory Ventilation. (Cheryll K. Hagus). Chapter 20. Assist/Control Ventilation. (Steven M. Donn, Sunil K. Sinha). Chapter 21. Synchronized Intermittent Mandatory Ventilation. (Steven M. Donn, Sunil K. Sinha). Chapter 22. Volume-Controlled Ventilation. (Steven M. Donn, Kenneth P. Bandy). Chapter 23. Pressure Support Ventilation. (Sunil K. Sinha, Steven M. Donn). Chapter 24. Pressure Control and Pressure-Regulated Volume-Controlled Ventilation. (Mary K. Dekeon). Section VI. Neonatal Ventilator. Chapter 25. VIP BIRD® Infant/Pediatric Ventilator. (Michael A. Becker, Steven M. Donn). Chapter 26. Dräger Babylog 8000 Plus® Infant Care Ventilator. (Donald M. Null, Jr.). Chapter 27. SLE 2000® (HFO) Ventilator. (J. Harry Baumer). Chapter 28. Sechrist Model IV-200 SAVI® Ventilator. (S. David Ferguson). Chapter 29. Newport Wave® Ventilator. (Robert L. Chatburn). Chapter 30. Bear Cub 750 PSV® Infant Ventilator. (Cheryll K. Hagus). Chapter 31. Siemens Servo 300® Ventilator. (Mary K. Dekeon). Chapter 32. Infant Star® Ventilator. (Graham Bernstein). Section VII. Neonatal Apnea. Chapter 33. Apnea Syndromes. (Charles A. Pohl, Alan R. Spitzer). Chapter 34. Diagnosis of Apnea. (Charles A. Pohl, Alan R. Spitzer). Chapter 35. Treatment of Apnea. (Charles A. Pohl, Alan R. Spitzer). Section VIII. High-Frequency Ventilation. Chapter 36. General Concepts of High-Frequency Ventilation. (Bert Bunnell). Chapter 37. High-Frequency Jet Ventilation and the Bunnell Life Pulse® High-Frequency Jet Ventilator. (Martin Keszler). Chapter 38. High-Frequency Oscillatory Ventilation. (Reese H. Clark, Dale R. Gerstmann). Chapter 39. SensorMedics 3100A® High-Frequency Oscillatory Ventilator. (Jeanette M. Asselin). Section IX. Management of Specific Respiratory Disorders. Chapter 40. Respiratory Distress Syndrome. (Steven M. Donn, Sunil K. Sinha). Chapter 41. Meconium Aspiration Syndrome. (Thomas E. Wiswell). Chapter 42. Neonatal Pneumonia. (Roger G. Faix). Chapter 43. Persistent Pulmonary Hypertension of the Newborn. (Robert E. Schumacher, Steven M. Donn). Chapter 44. Neonatal Pulmonary Hemorrhage. (Tonse N.K. Raju). Chapter 45. Thoracic Air Leaks. (Kim K. Tekkanat, Steven M. Donn). Chapter 46. Congenital Diaphragmatic Hernia. (David Field). Chapter 47. Pulmonary Hypoplasia. (David Field). Chapter 48. Bronchopulmonary Dysplasia. (Jonathan M. Davis). Section X. Complications of Mechanical Ventilation. Chapter 49. Airway and Respiratory Complications of Mechanical Ventilation. (Steven M. Donn, Sunil K. Sinha). Chapter 50. Patent Ductus Arteriosus. (Jonathan P. Wyllie). Chapter 51. Neurologic Complications of Mechanical Ventilation. (Jeffrey M. Perlman). Chapter 52. Retinopathy of Prematurity. (Alistair R. Fielder). Section XI. Sedation and Control of Pain. Chapter 53. Assessment of Pain and Sedation. (Susan Kidd, Neil McIntosh). Chapter 54. Pharmacologic Intervention. (Gopi Menon, Christine A. Walker, Neil McIntosh.). Chapter 55. Effects of Inadequate Analgesia or Sedation. (Jan Reiss, Neil McIntosh). Section XII. Weaning from Mechanical Ventilation. Chapter 56. Essentials of Weaning. (Steven M. Donn, Sunil K. Sinha). Chapter 57. Weaning Strategies. (Steven M. Donn, Sunil K. Sinha). Chapter 58. Adjunctive Treatments for Weaning. (Steven M. Donn, Sunil K. Sinha). Chapter 59. Impediments to Weaning. (Steven M. Donn, Sunil K. Sinha). Chapter 60. Extubation and Postextubation Care. (Steven M. Donn, Sunil K. Sinha). Section XIII. Nursing Care. Chapter 61. Nursing Documentation. (Mary E. Linton). Chapter 62. Chest Physiotherapy/Postural Drainage. (Jill M. Neubert). Chapter 63. Endotracheal Tube Suctioning. (Mary E. Linton). Section XIV Special Procedures. Chapter 64. Laryngoscopy and Endotracheal Intubation. (Sam W. J. Richmond). Chapter 65. Replacing the Endotracheal Tube. (Sunil K. Sinha, Jonathan P. Wyllie, Steven M. Donn). Chapter 66. Transillumination. (Kim K. Tekkanat, Steven M. Donn). Chapter 67. Evacuation of Air Leaks. (Kim K. Tekkanat, Steven M. Donn). Chapter 68. Vascular Access. (Steven M. Donn, Kim K. Tekkanat). Chapter 69. Bronchoscopy. (Neil N. Finer). Chapter 70. Tracheostomy. (Steven M. Donn). Section XV. Pharmacologic Agents Used in Respiratory Care. Chapter 71. Surfactants. (Dharmapuri Vidyasagar). Chapter 72. Adjunctive Pharmacologic Agents. (Sam W.J. Richmond). Section XVI. Transport of Ventilated Babies. Chapter 73. Transport Equipment. (Steven M. Donn, Molly R. Gates). Chapter 74. Stabilization of the Transported Newborn. (Steven M. Donn, Molly R. Gates). Chapter 75. Special Considerations. (Steven M. Donn, Molly R. Gates). Section XVII. Alternative Therapies for Intractable Respiratory Failure. Chapter 76. Extracorporeal Membrane Oxygenation. (Robert E. Schumacher). Chapter 77. Inhaled Nitric Oxide Therapy. (Martha Nelson). Chapter 78. Liquid Ventilation for Neonatal Respiratory Failure. (David S. Foley, Ronald B. Hirschl). Section XVIII. Outcome of Neonatal Intensive Care. Chapter 79. Discharge Planning of the NICU Graduate. (Win Tin, Unni Wariyar). Chapter 80. Follow-Up of the NICU. (Graduate.Win Tin, Unni Wariyar). Section XIX. Ethical Considerations. Chapter 81. Initiation of Life Support at the Border of Viability. (Daniel G. Batton, Jeffrey Maisels). Chapter 82. Withdrawal of Ventilatory Support. (Malcolm L. Chiswick). Section XX. Ventilatory Case Studies. Chapter 83. Ventilatory Case Studies. (Marie C. McGettigan, Jay P. Goldsmith). Appendix. Index.
£125.06
Cambridge University Press Cystic Fibrosis
Book SynopsisAn informative and enjoyable book introducing the condition Cystic Fibrosis to children and their families, providing comfort, hope, and key information. Featuring easy to understand language, helpful facts and fun color illustrations, this book is part of the innovative series The Strength of My Scars by surgeon, Maria Baimas-George.Table of ContentsCystic Fibrosis – Wacky Juice Machines.
£11.99
Taylor & Francis Ltd Asthma in the Workplace
Book SynopsisAsthma can be caused and aggravated by occupational factors in working adults. Agents that are responsible for occupational asthma are either sensitizers or irritants. Prevention is important to reduce the impact of the disease. This new edition of Asthma in the Workplace focuses on recent developments that are reflected by an impressive addition to the scientific literature. This fifth edition retains key elements that have made the success of previous editions: worldwide contributors, variety of topics covered, presentation of key aspects using workplace scenarios and case histories. This new comprehensive edition is intended to be of interest for health professionals, researchers, students, practitioners and various professionals involved in the assessment and management of workers exposed to occupational factors that may cause or exacerbate asthma. Key Features Comprehensive coverage of all aspects of work-related asthma, includinTable of ContentsTable of Contents Part I : Introduction 1. Definition and classification of asthma in the workplace 2. Historical aspects of occupational asthma 3. Disease occurrence and risk factors 4. Mechanisms, genetics, and pathophysiology Part II : Assessment 5. Assessment of the worker 6. Assessment of the workplace 7. Immunological and inflammatory assessments 8. Functional assessment Part III : Management 9. Management of the worker 10. Prevention 11A. Impairment and disability evaluations: I. Psychosocial, economic, and medicolegal aspects 11B. Impairment and disability evaluation: II. Various legislations Part IV : Specific agents causing immunological occupational asthma 12. Occupational asthma in the baking industry 13. Asthma and allergy to animals, fish and shellfish 14. Polyisocyanates and their prepolymers 15. Western red cedar and other wood dusts 16. Metals 17. Cleaning agents 18. Various high- and low-molecular weight agents Part V : Specific disease entities and variants 19. Irritant-induced asthma and reactive airways dysfunction syndrome 20. Asthma exacerbated at work 21. Eosinophilic bronchitis 22. Occupational rhinitis 23. Airway diseases due to organic dust exposure 24. Occupational hypersensitivity pneumonitis and organic dust toxic syndrome 25. Chronic obstructive airway disease due to occupational exposure 26. Building-related illnesses and mold-related conditions 27. Occupational urticaria and allergic contact dermatitis
£90.24
Taylor & Francis Ltd Inhaled Delivery Systems for the Treatment of
Book SynopsisInhaled therapies form the cornerstone for treatment of patients with asthma and COPD. Evolving technology has resulted in availability of a wide range of devices for delivery of inhaled drugs. The four different delivery systems -- pressurized metered-dose inhalers, slow mist inhalers, dry powder inhalers, and nebulizers -- are unique in design and require distinct inhalational instructions for correct use. This book provides current information about inhalation devices, including their advantages and disadvantages, with guidance for optimal techniques of use. The book emphasizes appropriate selection of inhalation devices based on patient and health care professional factors as well as device attributes that allow selection of the right medication in the right inhalation device at the right time for the right patient.Key Features: Addresses the objective of precision medicine the right medication in the right inhaler device at the right time. Inputs by internationaTable of ContentsForeword. About the Editors. List of Contributors. Introduction. Principles of Inhaled Therapy. Goals of Pharmacotherapy for Asthma and COPD. Pressurized Metered-Dose Inhalers (pMDI). Spacers and Valved Holding Chambers. Slow Mist Inhalers. Dry Powder Inhalers. Digital Inhalers for the Management of Obstructive Lung Diseases. Nebulizers. Inhalation Therapy in Infants and Children. Selection of Inhaler Delivery System for Adult Outpatients. Inhalation Therapy in the Intensive Care Unit. Inhaled Therapy for Other Respiratory Diseases: Cystic Fibrosis and Non-Cystic Fibrosis Bronchiectasis. Inhaled Therapy for Other Respiratory Diseases: Pulmonary Hypertension. Regulatory Considerations Related to Inhaled. Delivery Systems. Index.
£46.54
Cambridge University Press Respiratory Disease in Pregnancy
Book SynopsisRespiratory diseases affect a large proportion of the population and can cause complications when associated with pregnancy. Pregnancy induces profound anatomical and functional physiological changes in the mother, and subjects the mother to pregnancy-specific respiratory conditions. Reviewing respiratory conditions both specific and non-specific to pregnancy, the book also addresses related issues such as smoking and mechanical ventilation. Basic concepts for the obstetrician are covered, including patient history, physiology and initial examinations. Topics such as physiological changes during pregnancy and placental gas exchange are discussed for the non-obstetrician. Guidance is practical, covering antenatal and post-partum care, as well as management in the delivery suite. An essential guide to respiratory diseases in pregnancy, this book is indispensable to both obstetricians and non-obstetric physicians managing pregnant patients.Trade Review'Overall, the book is quite timely given the current COVID-19 pandemic … The book is well written and easy to read. It provides excellent foundational knowledge … For the obstetrician, it is a great resource to facilitate more educated exchanges with consultants. For non-obstetricians consulted on obstetric patients, it provides a nice review of how pregnant women are different from non-pregnant adults. There are not many books dedicated to just the respiratory system, which makes it more valuable to healthcare providers looking for this specific type of information.' Vanessa Laibl Rogers, Doody's Book Review ServiceTable of ContentsList of contributors; Section 1. The Basics – for the Obstetrician: 1. Respiratory physiology and terminology Timothy Crozier; 2. Pulmonary assessment in pregnancy Tabassum Firoz; 3. Approach to common respiratory problems in pregnancy Karen Patterson; Section 2. The Basics – for the Non-Obstetrician: 4. Cardiopulmonary physiological alterations in pregnancy Niamh Hayes and Thomas Drew; 5. Gas exchange across the placenta Brahmdeep S. Saini, Janna L. Morrison and Mike Seed; Section 3. Pulmonary Conditions Not Specific to Pregnancy: 6. Pulmonary infections in pregnancy Priya Daniel, Timothy Hills and Wei Shen Lim; 7. Asthma in pregnancy Danish Ahmad and Erika Yoo; 8. Cystic fibrosis in pregnancy Melanie Chin and D. Elizabeth Tullis; 9. Restrictive lung disease in pregnancy Stephen Lapinsky; 10. Pulmonary thromboembolic disease in pregnancy Wee-Shian Chan; 11. Pulmonary hypertension in pregnancy Liesbeth ten Klooster, Vicki J. Wilson, Ruth Newton, Karen Selby, Suarabh V Gandhi and David G Kiely; 12. Sickle chest syndromes in pregnancy Ann Kinga Malinowski and Nadine Shehata; 13. Sleep-disordered breathing in pregnancy Jennifer E. Dominguez and Ghada Bourjeily; 14. Acute respiratory distress syndrome and respiratory failure in pregnancy Justin Seashore and Alexander Duarte; 15. Other pulmonary conditions in pregnancy Muhammed Ehtisham, Humnah Khudayar and Patricia Russo-Magno; Section 4. Pulmonary Conditions Related to Pregnancy: 16. Dyspnea of pregnancy Stephen Lapinsky and Ghada Bourjeily; 17. Amniotic fluid embolism syndrome Marie Baldisseri; 18. Pregnancy-associated pulmonary edema Lisa Moore; Section 5. Other Pulmonary Issues in Pregnancy: 19. Smoking in pregnancy Catherine Chamberlain; 20. Radiological imaging of the chest in pregnancy Shital Gandhi and Siobhan Bacon; 21. Respiratory drug therapy in pregnancy Nika Mehta; 22. Biological and immunosuppressive respiratory therapy in pregnancy Bernadette Jenner and Catherine Nelson-Piercy; 23. Oxygen therapy in pregnancy Daniela Vaquez and Gustavo A. Plotnikow; 24. Airway management in pregnancy Kyle Jespersen and Michaela K. Farber; 25. Mechanical ventilation in pregnancy José Rojas-Suarez and Jezid Miranda; Index.
£83.59
John Wiley and Sons Ltd Molecular Aspects of Aging
Book SynopsisMolecular Aspects of Aging: Understanding Lung Aging covers recent research in the mechanisms that contribute to cellular senescence.Table of ContentsContributors xi Preface xiii 1 The Demography of Aging 1 David E. Bloom and Sinead Shannon 1.1 Introduction 1 1.2 Demographic trends 1 1.2.1 Fertility rates 2 1.2.2 Mortality rates and life expectancy 2 1.2.3 Proportion of older people 3 1.3 Impact of aging 4 1.3.1 Noncommunicable disease trends 4 1.3.2 Risk factors 5 1.3.3 Impact of NCDs on health and disability 6 1.3.4 Increase in multimorbidities 7 1.3.5 Impact on expenditure 7 1.4 Policy responses 8 1.4.1 Preventing and managing NCDs 8 1.4.2 Promoting exercise 9 1.4.3 Monitoring health-risk behaviors (and chronic health conditions) 9 1.5 Conclusion 9 References 10 2 The Omics of Aging: Insights from Genomes upon Stress 13 Ismene Karakasilioti, Anna Ioannidou, and George A. Garinis 2.1 Introduction 13 2.2 Safeguarding the nuclear genome 14 2.3 NER progerias and their connection to lifespan regulatory mechanisms 15 2.4 Triggering a survival response in the absence of a DNA repair defect 16 2.5 The omics connection between progeria and longevity 19 2.6 Triggering of systemic versus cell-autonomous features of the survival response 20 2.7 The omics connection between NER progeria, transcription, and longevity 21 2.8 Future perspectives 22 References 22 3 Protein Quality Control Coming of Age 27 Silke Meiners 3.1 Introduction 27 3.2 The aging molecular chaperone network 29 3.3 Protein degradation pathways in aging 30 3.3.1 Lysosomal autophagy pathway 30 3.3.2 Ubiquitin–proteasome system 32 3.4 Compartment-specific protein quality control 34 3.4.1 The aging ER stress response 34 3.5 Conclusion 35 References 35 4 Telomerase Function in Aging 41 Rodrigo T. Calado 4.1 Telomeres 41 4.2 Telomerase 43 4.3 Telomeres and human disease 45 4.3.1 Telomere dysfunction in the lungs 46 4.4 Telomeres biology, aging, and longevity 47 4.5 Conclusion 48 References 48 5 The Cellular Senescence Program 53 Pooja Shivshankar and Claude Jourdan Le Saux 5.1 Cellular senescence and evidence of senescence in a cell 53 5.1.1 Characteristics of senescent cells and the inflammatory microenvironment 53 5.1.2 Detection of senescent cells in vitro and in vivo 54 5.2 Conditions associated with cellular senescence 55 5.2.1 Oxidative stress 55 5.2.2 DNA damage 55 5.2.3 Cell cycle arrest and senescence 56 5.3 Mechanisms/pathways of senescence induction 56 5.3.1 The p53/p21 pathway 56 5.3.2 The p16/pRB pathway 57 5.3.3 Convergence/coactivation of p53/p21 and p16/pRB pathways 57 5.3.4 Induction of senescence via molecular signaling 57 5.4 Cellular senescence in aging and age-related diseases of the lungs 58 5.4.1 Normal aging 59 5.4.2 Pneumonia 59 5.4.3 Chronic obstructive pulmonary disease 60 5.4.4 Idiopathic pulmonary fibrosis 60 5.5 Conclusion 61 References 61 6 Signaling Networks Controlling Cellular Senescence 67 Leena P. Desai, Yan Y. Sanders, and Victor J. Thannickal 6.1 Introduction 67 6.2 Classification of cellular senescence 69 6.2.1 Intrinsic pathway 69 6.2.2 Extrinsic pathway 69 6.2.3 Reversibility of cellular senescence 70 6.3 Cross talk of signaling pathways 70 6.3.1 Protein kinases 70 6.3.2 Metabolic pathways 71 6.3.3 Mitochondria and reactive oxygen species 71 6.3.4 Integrin and focal adhesion signaling 72 6.3.5 Transforming growth factor-β1 73 6.3.6 Epigenetic mechanisms 73 6.4 Conclusion 76 References 77 7 Immune Senescence 85 Kevin P. High 7.1 Introduction 85 7.2 Barrier defenses and innate immunity in older adults 86 7.2.1 Barrier defenses 86 7.2.2 Innate immunity 86 7.3 Adaptive immune responses 88 7.3.1 B cell number and function 88 7.3.2 T cell number, subtypes, and function 89 7.3.3 T cell activation, differentiation, exhaustion, and senescence 90 7.4 Consequences of immune senescence 91 7.4.1 Impaired vaccine responses, increased risk of infection, and age-related illness 91 7.4.2 Immune senescence: A cause of aging itself 93 7.5 Conclusion 94 References 95 8 Developmental and Physiological Aging of the Lung 99 Kent E. Pinkerton, Lei Wang, Suzette M. Smiley-Jewell, Jingyi Xu, and Francis H.Y. Green 8.1 Introduction 99 8.2 The aging lung 99 8.2.1 Alterations in lung function and anatomy 99 8.2.2 Oxidative stress and lung antioxidant defenses 101 8.2.3 Immune system changes with aging 101 8.2.4 Body mass 102 8.2.5 Airway receptor and endocrine changes with aging 103 8.3 An animal model of the aging lung: The rat 104 8.3.1 The tracheobronchial tree and epithelium of the aging rat 104 8.3.2 Parenchymal lung structure in the aging rat 105 8.3.3 Alveolar tissue compartments 106 8.4 Conclusion 110 Acknowledgments 110 References 111 9 Mouse Models to Explore the Aging Lung 117 Mingyi Wang and Deepak A. Deshpande 9.1 Pulmonary changes during aging 117 9.1.1 Advantages of mouse models for studying physiological lung changes 118 9.2 Key findings from mouse models of aging 119 9.2.1 Longevity and lung function in mice 120 9.2.2 Different strains of mice have different alterations in lung mechanics 120 9.2.3 Transgenic mouse model to study aging in the lungs 121 9.3 Age is a risk factor for obstructive pulmonary diseases 123 9.4 Challenges ahead 124 9.5 Conclusion 125 Acknowledgments 126 References 126 10 Evidence for Premature Lung Aging of the Injured Neonatal Lung as Exemplified by Bronchopulmonary Dysplasia 131 Anne Hilgendorff 10.1 Introducing bronchopulmonary dysplasia 131 10.2 Altered pulmonary function in infants with BPD 132 10.3 Response to injury 133 10.3.1 Oxidative stress response 134 10.3.2 Extracellular matrix remodeling 136 10.3.3 Inflammation 136 10.3.4 Morphogenetic response 137 10.4 Prenatal and genetic predisposition 137 10.5 Conclusion 138 References 138 11 Remodeling of the Extracellular Matrix in the Aging Lung 145 Jesse Roman 11.1 Introduction 145 11.2 The aging lung 145 11.3 Activation of tissue remodeling in the senescent lung 146 11.4 The aging lung fibroblast 148 11.5 Potential role of oxidant stress in triggering remodeling in the aging lung 149 11.6 Implications for remodeling of the lung extracellular matrix in the aged lung 150 11.7 Conclusions 152 Acknowledgments 154 References 154 12 Aging Mesenchymal Stem Cells in Lung Disease 159 Maria G. Kapetanaki, Ana L. Mora, and Mauricio Rojas 12.1 Aging and lung diseases 159 12.2 Mesenchymal stem cells (MSCs) 160 12.2.1 Description of MSCs 160 12.2.2 Characterization of MSCs 160 12.2.3 Functional properties of MSCs 161 12.3 Impact of aging on mesenchymal stem cells 162 12.3.1 In vitro aging of MSCs 162 12.3.2 Age-related changes in B-MSCs 163 12.3.3 Aging of B-MSCs versus aging of the organism 163 12.4 B-MSCs in disease 164 12.5 B-MSCs in therapy 166 12.5.1 Ex vivo expansion 166 12.5.2 Conditions affecting the expansion 167 12.5.3 Autologous versus allogeneic B-MSCs 167 12.5.4 Combination of cell preparations 167 12.5.5 Delivery and targeting 167 12.6 Conclusion 167 Acknowledgments 168 References 168 13 COPD as a Disease of Premature Aging 173 Laurent Boyer, Jorge Boczkowski, and Serge Adnot 13.1 Introduction 173 13.2 Senescent cells contribute to the pathogenesis of COPD 174 13.2.1 Accumulation of senescent cells in COPD lungs 174 13.2.2 Inflammation and lung-cell senescence in COPD 175 13.2.3 Emphysema and lung-cell senescence in COPD 176 13.2.4 Pulmonary hypertension and cell senescence in COPD 177 13.3 Lung dysfunction and the general process of premature aging in COPD 179 13.3.1 Clinical manifestations of premature aging in COPD patients 179 13.3.2 Role for lung alterations in systemic premature aging during COPD 180 13.4 Conclusion 181 References 181 14 Lung Infections and Aging 185 Jacqueline M. Kruser and Keith C. Meyer 14.1 Introduction 185 14.2 Aging and immunosenescence 185 14.2.1 Innate immunity 187 14.2.2 Adaptive immunity 188 14.2.3 Autoimmunity 189 14.2.4 Lung-specific changes in immunity with aging 190 14.3 Inflamm-aging and susceptibility to infection 190 14.4 Respiratory infection and regulation of host responses 192 14.5 Preventing respiratory infection 194 14.6 Summary and conclusions 195 References 195 Index 201
£105.26
John Wiley and Sons Ltd Essential Respiratory Medicine
Book SynopsisA succinct yet comprehensive overview of respiratory medicine, written for students and professionals Essential Respiratory Medicine is an indispensable text offering an understanding of respiratory conditions and their clinical management within evidence-based guidelines. Containing information on taking a medical history, performing examinations and investigations, diagnosis and the management of respiratory conditions, this comprehensive text was put together by a noted expert in the field. Written in an accessible manner, Essential Respiratory Medicine contains the foundational science associated with respiratory medicine, a wide-variety of practical procedures, helpful diagrams, and self-assessments designed to enhance understanding of the material presented. The text covers a variety of conditions as well as providing suggestions for engaging with patients at different stages of care. This important resource: Demonstrates an effective approach to patients presenting with common respiratory symptoms Includes a description of all key practical procedures with diagramsDiscusses acute management of important respiratory emergenciesCovers both acute and chronic diseaseContains a companion website containing a range of learning materials, including downloadable management summaries and algorithms, an image bank, videos of patient examination, example respiratory sounds and multiple-choice questions Essential Respiratory Medicine is an essential resource for anyone on a clinical placement, rotation, or training programme in respiratory medicine.Table of ContentsAbout the author ix Acknowledgements xi About the companion website xiii 1 Introduction to respiratory medicine 1 2 Embryology, anatomy, and physiology of the lung 5 3 Pharmacology of the lung 29 4 Common respiratory investigations 51 5 Common presentations of respiratory disease 83 6 Obstructive airways disease 105 7 Diffuse parenchymal lung disease 137 8 Respiratory infections 173 9 Lung cancer 205 10 Pleural disease 235 11 Pulmonary embolus, pulmonary hypertension, and vasculitides 267 12 Suppurative lung disease 293 13 Respiratory failure 317 14 Sleep‐related disorders 333 15 Occupational, environmental, and recreational lung disease 353 16 Disorders of the mediastinum 369 17 Acute lung injury and acute respiratory distress syndrome 383 Index 395
£38.66
John Wiley & Sons Inc Comprehensive Tracheostomy Care
Book SynopsisComprehensive Tracheostomy Care is a resource developed by the UK National Tracheostomy Safety Project (NTSP) to help promote and facilitate the safe management of tracheostomies and laryngectomies.Table of ContentsNTSP Editorial board, vii Preface, ix Acknowledgements, xi Competing interests, xiii Disclaimer, xv Contact details and further information, xvii Executive summary and Key recomendations, xix 1 How the NTSP resources were developed, 1 2 What is a tracheostomy? What is a laryngectomy?, 3 3 Why and how a tracheostomy is performed, 7 4 Different types of tracheostomy tubes, 20 5 Management of the day-to-day needs of the patient with a tracheostomy and laryngectomy, 28 6 Complications, 67 7 Redflags, 72 8 Emergency management of the patient with a tracheostomy or laryngectomy, 74 9 Paediatric tracheostomy care (with Great Ormond Street Hospital, London), 85 10 Infrastructure considerations, 111 11 Competencies for staff caring for patients with tracheostomies or laryngectomies, 117 12 Courses, 122 13 Human factors, 124 Bibliography, 131
£35.96
John Wiley & Sons Inc Pulmonary Drug Delivery
Book SynopsisDrug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products.Table of ContentsList of Contributors xiii Series Preface xvii Preface xix 1. Lung Anatomy and Physiology and Their Implications for Pulmonary Drug Delivery 1Rahul K. Verma, Mariam Ibrahim, and Lucila Garcia-Contreras 1.1 Introduction 2 1.2 Anatomy and Physiology of Lungs 2 1.2.1 Macro- and Microstructure of the Airways and Alveoli as It Pertains to Drug Delivery 2 1.2.2 Lung Surfactant 4 1.2.3 Pulmonary Blood Circulation 5 1.3 Mechanisms of Aerosol Deposition 5 1.3.1 Impaction 6 1.3.2 Sedimentation 6 1.3.3 Interception 6 1.3.4 Diffusion 7 1.4 Drug Absorption 7 1.4.1 Mechanisms of Drug Absorption from the Lungs 7 1.5 Physiological Factors Affecting the Therapeutic Effectiveness of Drugs Delivered by the Pulmonary Route 8 1.5.1 Airway Geometry 8 1.5.2 Inhalation Mode 8 1.5.3 Airflow Rate 9 1.5.4 Mechanism of Particle Clearance 9 1.5.5 Lung Receptors 10 1.5.6 Disease States 11 1.5.7 Effect of Age and Gender Difference 11 1.6 Computer Simulations to Describe Aerosol Deposition in Health and Disease 11 1.6.1 Semiempirical Models 12 1.6.2 Deterministic Models 12 1.6.3 Trumpet Models (One-Dimensional) 12 1.6.4 Stochastic, Asymmetric Generation Models 13 1.6.5 Computation Fluid Dynamics (CFD)-Based Model 13 1.7 Conclusions 13 References 14 2. The Role of Functional Lung Imaging in the Improvement of Pulmonary Drug Delivery 19Andreas Fouras and Stephen Dubsky 2.1 Introduction 19 2.1.1 Particle Deposition 20 2.1.2 Regional Action of Delivered Drug 22 2.1.3 The Role of Functional Lung Imaging in Pulmonary Drug Delivery 22 2.2 Established Functional Lung Imaging Technologies 23 2.2.1 Computed Tomography 23 2.2.2 Ventilation Measurement using 4DCT Registration-based Methods 24 2.2.3 Hyperpolarized Magnetic Resonance Imaging 24 2.2.4 Electrical Impedance Tomography 25 2.2.5 Nuclear Medical Imaging (PET/SPECT) 25 2.3 Emerging Technologies 26 2.3.1 Phase-contrast Imaging 26 2.3.2 Grating Interferometry 27 2.3.3 Propagation-based Phase-contrast Imaging 28 2.3.4 Functional Lung Imaging using Phase Contrast 28 2.3.5 Laboratory Propagation-based Phase-contrast Imaging 29 2.4 Conclusion 30 References 31 3. Dry Powder Inhalation for Pulmonary Delivery: Recent Advances and Continuing Challenges 35Simone R. Carvalho, Alan B. Watts, Jay I. Peters, and Robert O. Williams III 3.1 Introduction 36 3.2 Dry Powder Inhaler Devices 37 3.2.1 Overview 37 3.2.2 Recent Innovations in Dry Powder Inhaler Technology 39 3.3 New Developments in DPI Formulations and Delivery 43 3.3.1 Particle Surface Modification 43 3.3.2 Particle Engineering Technology for Pulmonary Delivery 44 3.4 Characterization Methods of Dry Powder Inhaler Formulations 50 3.5 Conclusion 52 References 53 4. Pulmonary Drug Delivery to the Pediatric Population – A State-of-the-Art Review 63Marie-Pierre Flament 4.1 Introduction 63 4.2 Patient Consideration 64 4.2.1 Anatomy and Physiology of Children’s Lungs 64 4.2.2 Nasal Versus Oral Inhalation 65 4.2.3 Patient-related Factors Influencing Aerosol Deposition 66 4.2.4 Age and Dosage Forms of Choice 67 4.3 Delivery Systems for the Pediatric Population 69 4.3.1 Nebulizers 69 4.3.2 Pressurized Metered Dose Inhalers 72 4.3.3 Dry Powder Inhalers 73 4.3.4 Interfaces 74 4.4 Recommendations 80 4.5 Conclusion 82 References 82 5. Formulation Strategies for Pulmonary Delivery of Poorly Soluble Drugs 87Nathalie Wauthoz and Karim Amighi 5.1 Introduction 88 5.1.1 In vivo Fate of Inhaled Poorly Water-soluble Drugs 89 5.1.2 The Pharmacokinetics of Inhaled Poorly Water-soluble Drugs Administered for Local and Systemic Action 92 5.1.3 Formulation Strategies for Pulmonary Delivery of Poorly Water-soluble Drugs 93 5.2 Co-solvents 93 5.3 Cyclodextrins 97 5.4 PEGylation 99 5.5 Reduction of Size to Micro-/Nanoparticles 100 5.5.1 Nanocrystal Suspension 101 5.5.2 Nanocrystals in a Hydrophilic Matrix System 102 5.5.3 Nanoclusters 103 5.6 Solid Dispersion/Amorphization 103 5.7 Micelles 106 5.8 Liposomes 108 5.9 Solid Lipid Nanoparticles and Nanostructured Lipid Carriers 110 5.10 Conclusion 111 References 114 6. Lipidic Micro- and Nano-Carriers for Pulmonary Drug Delivery – A State-of-the-Art Review 123Yahya Rahimpour, Hamed Hamishehkar, and Ali Nokhodchi 6.1 Introduction 124 6.2 Pulmonary Drug Delivery 125 6.3 Liposomal Pulmonary Delivery 126 6.4 Nebulization of Liposomes 126 6.5 Liposomal Dry-powder Inhalers 128 6.6 Solid Lipid Microparticles in Pulmonary Drug Delivery 129 6.7 Solid Lipid Nanoparticles in Pulmonary Drug Delivery 131 6.8 Nanostructured Lipid Carrier (NLC) in Pulmonary Drug Delivery 133 6.9 Nanoemulsions in Pulmonary Drug Delivery 134 6.10 Conclusion and Perspectives 135 References 136 7. Chemical and Compositional Characterisation of Lactose as a Carrier in Dry Powder Inhalers 143Rim Jawad, Gary P. Martin and Paul G. Royall 7.1 Introduction 144 7.2 Production of Lactose 145 7.3 Lactose: Chemical Forms, Solid-State Composition, Physicochemical Properties 147 7.4 Epimerisation of Lactose 150 7.5 Analysis of Lactose 151 7.5.1 Powder X-ray Diffraction 152 7.5.2 Nuclear Magnetic Resonance 153 7.5.3 Infrared Spectroscopy 156 7.5.4 Differential Scanning Calorimetry 157 7.5.5 Polarimetry 158 7.6 The Influence of the Chemical and Solid-State Composition of Lactose Carriers on the Aerosolisation of DPI Formulations 159 7.7 Conclusions 163 References 163 8. Particle Engineering for Improved Pulmonary Drug Delivery Through Dry Powder Inhalers 171Waseem Kaialy and Ali Nokhodchi 8.1 Introduction 172 8.2 Dry Powder Inhalers 172 8.3 Particle Engineering to Improve the Performance of DPIs 172 8.3.1 Crystallization 173 8.3.2 Spray-drying 174 8.3.3 Spray-freeze-drying 177 8.3.4 Supercritical Fluid Technology 177 8.3.5 Pressure Swing Granulation (PSG) Technique 178 8.4 Engineered Carrier Particles for Improved Pulmonary Drug Delivery from Dry Powder Inhalers 178 8.5 Relationships between Physical Properties of Engineered Particles and Dry Powder Inhaler Performance 182 8.5.1 Particle Size 182 8.5.2 Flow Properties 184 8.5.3 Particle Shape 185 8.5.4 Particle Surface Texture 187 8.5.5 Fine Particle Additives 188 8.5.6 Surface Area 188 8.6 Conclusions 189 References 189 9. Particle Surface Roughness – Its Characterisation and Impact on Dry Powder Inhaler Performance 199Bernice Mei Jin Tan, Celine Valeria Liew, Lai Wah Chan, and Paul Wan Sia Heng 9.1 Introduction 200 9.2 What is Surface Roughness? 200 9.3 Measurement of Particle Surface Roughness 202 9.3.1 General Factors to Consider During a Measurement 202 9.3.2 Direct Methods to Profile or Visualise Surface Roughness 204 9.3.3 Indirect Measurement of Surface Roughness 206 9.4 Impact of Surface Roughness on Carrier Performance – Theoretical Considerations 206 9.4.1 Mixing and Blend Stability 206 9.4.2 Drug-carrying Capacity 207 9.4.3 Drug Adhesion 207 9.4.4 Drug Detachment 208 9.4.5 Particle Arrangement in Ordered Mixtures After the Addition of Fine Excipient 209 9.5 Particle Surface Modification 210 9.5.1 Spray Drying 210 9.5.2 Solution Phase Processing 211 9.5.3 Crystallisation 213 9.5.4 Sieving 213 9.5.5 Fluid-bed Coating 213 9.5.6 Dry Powder Coating 213 9.6 Conclusion 215 References 215 10. Dissolution: A Critical Performance Characteristic of Inhaled Products? 223Ben Forbes, Nathalie Hauet Richer, and Francesca Buttini 10.1 Introduction 223 10.2 Dissolution of Inhaled Products 224 10.2.1 Dissolution Rate 224 10.2.2 Dissolution in the Lungs 224 10.2.3 Case for Dissolution Testing 225 10.2.4 Design of Dissolution Test Systems 226 10.3 Particle Testing and Dissolution Media 226 10.3.1 Particle Collection 226 10.3.2 Dissolution Media 229 10.4 Dissolution Test Apparatus 230 10.4.1 USP Apparatus 1 (Basket) 231 10.4.2 USP Apparatus 2 (Paddle) and USP Apparatus 5 (Paddle Over Disc) 232 10.4.3 USP Apparatus 4 (Flow-Through Cell) 232 10.4.4 Diffusion-Controlled Cell Systems (Franz Cell, Transwell, Dialysis) 233 10.4.5 Methodological Considerations 234 10.5 Data Analysis and Interpretation 235 10.5.1 Modelling 236 10.5.2 Comparing Dissolution Profiles (Model-independent Method for Comparison) 237 10.6 Conclusions 237 References 238 11. Drug Delivery Strategies for Pulmonary Administration of Antibiotics 241Anna Giulia Balducci, Ruggero Bettini, Paolo Colombo, and Francesca Buttini 11.1 Introduction 242 11.2 Antibiotics Used for the Treatment of Pneumoniae 243 11.3 Antibiotic Products for Inhalation Approved on the Market 244 11.4 Nebulisation 246 11.5 Antibiotic Dry Powders for Inhalation 250 11.5.1 Tobramycin 251 11.5.2 Capreomycin 252 11.5.3 Gentamicin 253 11.5.4 Ciprofloxacin 254 11.5.5 Levofloxacin 255 11.5.6 Colistimethate Sodium 256 11.6 Device and Payload of Dose 256 11.7 Conclusions 258 References 258 12. Molecular Targeted Therapy of Lung Cancer: Challenges and Promises 263Jaleh Barar, Yadollah Omidi, and Mark Gumbleton 12.1 Introduction 265 12.2 An Overview on Lung Cancer 266 12.3 Molecular Features of Lung Cancer 268 12.3.1 Tumor Microenvironment (TME) 269 12.3.2 Tumor Angiogenesis 269 12.3.3 Tumor Stromal Components 270 12.3.4 Pharmacogenetic Markers: Cytochrome P450 270 12.4 Targeted Therapy of Solid Tumors: How and What to Target? 271 12.4.1 EPR Effect: A Rational Approach for Passive Targeting 272 12.4.2 Toward Long Circulating Anticancer Nanomedicines 273 12.4.3 Active/Direct Targeting 273 12.4.4 Overcoming Multidrug Resistance (MDR) 273 12.4.5 Antibody-Mediated Targeting 274 12.4.6 Aptamer-Mediated Targeted Therapy 276 12.4.7 Folate Receptor-Mediated Targeted Therapy 276 12.4.8 Transferrin-Mediated Targeted Therapy 276 12.4.9 Targeted Photodynamic Therapy 277 12.4.10 Multimodal Theranostics and Nanomedicines 278 12.5 Final Remarks 278 References 279 13. Defining and Controlling Blend Evolution in Inhalation Powder Formulations using a Novel Colourimetric Method 285David Barling, David Morton, and Karen Hapgood 13.1 Introduction 286 13.1.1 Introduction to Blend Pigmentation 287 13.1.2 Previous Work in the Use of Coloured Tracers to Assess Powder Blending 288 13.1.3 Colour Tracer Properties and Approach to Blend Analysis 288 13.2 Uses and Validation 290 13.2.1 Assessment of Mixer Characteristics and Mixer Behaviour 290 13.2.2 Quantification of Content Uniformity and Energy Input 293 13.2.3 Detection and Quantification of Unintentional Milling during Mixing 295 13.2.4 Robustness of Method with Tracer Concentration 295 13.3 Comments on the Applied Suitability and Robustness in of the Tracer Method 296 13.4 Conclusions 297 Acknowledgements 297 References 297 14. Polymer-based Delivery Systems for the Pulmonary Delivery of Biopharmaceuticals 301Nitesh K. Kunda, Iman M. Alfagih, Imran Y. Saleem, and Gillian A. Hutcheon 14.1 Introduction 302 14.2 Pulmonary Delivery of Macromolecules 302 14.3 Polymeric Delivery Systems 303 14.3.1 Micelles 304 14.3.2 Dendrimers 305 14.3.3 Particles 305 14.4 Preparation of Polymeric Nano/microparticles 305 14.4.1 Emulsification Solvent Evaporation 306 14.4.2 Emulsification Solvent Diffusion 307 14.4.3 Salting Out 307 14.5 Formulation of Nanoparticles as Dry Powders 308 14.5.1 Freeze-drying 308 14.5.2 Spray-drying 309 14.5.3 Spray-freeze-drying 309 14.5.4 Supercritical Fluid Drying 310 14.6 Carrier Properties 310 14.6.1 Size 310 14.6.2 Morphology 311 14.6.3 Surface Properties 311 14.7 Toxicity of Polymeric Delivery Systems 311 14.8 Pulmonary Delivery of Polymeric Particles 312 14.9 Conclusions 313 References 313 15. Quality by Design: Concept for Product Development of Dry-powder Inhalers 321Al Sayyed Sallam, Sami Nazzal, Hatim S. AlKhatib, and Nabil Darwazeh 15.1 Introduction 322 15.2 Quality Target Product Profile (QTPP) 324 15.3 Critical Quality Attributes (CQA) 324 15.4 Quality Risk Management 325 15.5 Design of Experiments 326 15.6 Design Space 328 15.7 Control Strategies 328 15.8 Continual Improvement 329 15.9 Process Analytical Technology/Application in DPI 329 15.10 Particle Size 329 15.11 Crystallinity and Polymorphism 330 15.12 Scale-up and Blend Homogeneity 331 15.13 Applying of QbD Principles to Analytical Methods 331 15.14 Conclusion 332 References 332 16. Future Patient Requirements on Inhalation Devices: The Balance between Patient, Commercial, Regulatory and Technical Requirements 339Orest Lastow 16.1 Introduction 340 16.1.1 Inhaled Drug Delivery 340 16.1.2 Patients 340 16.2 Requirements 341 16.2.1 Patient Requirements 341 16.2.2 Technical Requirements 343 16.2.3 Performance Requirements 345 16.3 Requirement Specifications 346 16.3.1 Requirement Hierarchy 346 16.3.2 Developing the Requirements 347 16.4 Product Development 350 16.5 Conclusions 351 References 352 Index 353
£125.95
John Wiley & Sons Inc Delivery Systems for Tuberculosis Prevention and
Book SynopsisProvides a review of novel pharmaceutical approaches for Tuberculosis drugs Presents a novel perspective on tuberculosis prevention and treatment Considers the nature of disease, immunological responses, vaccine and drug delivery, disposition and response Multidisciplinary appeal, with contributions from microbiology, immunology, molecular biology, pharmaceutics, pharmacokinetics, chemical and mechanical engineering Table of ContentsList of Contributors xvi Foreword xviii Series Preface xxi Preface xxiii 1 Introduction: A Guide to Treatment and Prevention of Tuberculosis Based on Principles of Dosage Form Design and Delivery 1A.J. Hickey 1.1 Background 1 1.2 Dosage Form Classification 3 1.3 Controlled and Targeted Delivery 5 1.4 Physiological and Disease Considerations 6 1.5 Therapeutic Considerations 7 1.6 Conclusion 8 References 8 Section 1 Pathogen and Host 11 2 Host Pathogen Biology for Airborne Mycobacterium tuberculosis: Cellular and Molecular Events in the Lung 13Eusondia Arnett, Nitya Krishnan, Brian D. Robertson and Larry S. Schlesinger 2.1 Introduction 13 2.2 Lung 14 2.3 General Aspects of Mucus and Surfactant 17 2.4 General M. tuberculosis 18 2.5 M. tuberculosis Interaction with the Lung Macrophage 19 2.6 M. tuberculosis Interaction with other Respiratory Immune Cells 23 2.7 TB Granuloma 29 2.8 Conclusion 30 References 30 3 Animal Models of Tuberculosis 48David N. McMurray 3.1 Introduction 48 3.2 What is an Animal Model of TB? 49 3.3 How are Animal Models of TB Used? 50 3.4 TB Animal Models Currently Used for TB Drug and Vaccine Evaluation 51 3.5 Summary 58 References 59 Section 2 Immunological Intervention 67 4 Vaccine Preparation: Past, Present, and Future 69Dominique N. Price, Nitesh K. Kunda, Amber A. McBride and Pavan Muttil 4.1 Introduction 69 4.2 Early Efforts in TB Vaccine Development 71 4.3 Current BCG Vaccine Formulation 73 4.4 Novel TB Vaccination Strategies 76 4.5 Future Perspective 84 4.6 Conclusions 85 References 85 5 TB Vaccine Assessment 91Andre G. Loxton, Mary K. Hondalus and Samantha L. Sampson 5.1 Introduction 91 5.2 Preclinical Vaccine Assessment 92 5.3 Clinical Assessment of Vaccines 97 5.4 Laboratory Immunological Analysis and Assessment of Vaccine Trials 102 5.5 How well do the Available Preclinical Models Predict Vaccine Success in Humans? 103 References 105 Section 3 Drug Treatment 111 6 Testing Inhaled Drug Therapies for Treating Tuberculosis 113Ellen F. Young, Anthony J. Hickey and Miriam Braunstein 6.1 Introduction 113 6.2 The Need for New Drug Treatments for Tuberculosis 114 6.3 Inhaled Drug Therapy for Tuberculosis 114 6.4 Published Studies of Inhalation Therapy for TB 115 6.5 The Guinea Pig Model for Testing Inhaled Therapies for TB 116 6.6 Guinea Pig Study Design 117 6.7 Purchase and Grouping Animals 118 6.8 Infecting Guinea Pigs with Virulent Mycobacterium tuberculosis 118 6.9 Dosing Groups of Guinea Pigs with TB Drugs 119 6.10 Collecting Data 121 6.11 Aerosol Dosing Chambers and Practice 122 6.12 Nebulizer Aerosol Delivery Systems for Liquids 123 6.13 Dry-Powder Aerosol Delivery Systems for Solids 125 6.14 Summary 127 Acknowledgements 127 References 127 7 Preclinical Pharmacokinetics of Antitubercular Drugs 131Mariam Ibrahim and Lucila Garcia-Contreras 7.1 Introduction 131 7.2 Factors Influencing the Pharmacokinetic Behavior of Drugs 132 7.3 Pulmonary Delivery of Anti-TB Drugs 138 7.4 Pharmacokinetic Study Design 140 7.5 Implications of PK Parameters on Efficacy 144 7.6 Case Studies (Drugs Administered by Conventional and Pulmonary Routes) 146 References 152 8 Drug Particle Manufacture – Supercritical Fluid, High-Pressure Homogenization 156Kimiko Makino and Hiroshi Terada 8.1 Introduction 156 8.2 Preparation of Nano- and Micro-particles 157 References 159 9 Spray Drying Strategies to Stop Tuberculosis 161Jennifer Wong, Maurizio Ricci and Hak-Kim Chan 9.1 Introduction 161 9.2 Overview of Spray Drying 162 9.3 Advances in Spray Drying Technology 174 9.4 Anti-Tuberculosis Therapeutics Produced by Spray Drying 179 9.5 Conclusion 187 9.6 Acknowledgements 187 References 187 10 Formulation Strategies for Antitubercular Drugs by Inhalation 197Francesca Buttini and Gaia Colombo 10.1 Introduction 197 10.2 Lung Delivery of TB Drugs 198 10.3 Powders for Inhalation and Liquids for Nebulization 200 10.4 Antibacterial Powders for Inhalation: Manufacturing of Respirable Microparticles 202 10.5 Antibacterial Powders for Inhalation: Devices and Delivery Strategies 208 10.6 Conclusions and Perspectives 211 References 211 11 Inhaled Drug Combinations 213Sanketkumar Pandya, Anuradha Gupta, Rajeev Ranjan, Madhur Sachan, Atul Kumar Agrawal and Amit Misra 11.1 Introduction 213 11.2 Standard Combinations in Oral and Parenteral Regimens 214 11.3 The Rationale for Inhaled Therapies of TB 216 11.4 Combinations of Anti-TB Drugs with Other Agents 222 11.5 Formulation of Inhaled Drug Combinations 224 11.6 Conclusions 230 References 230 12 Ion Pairing for Controlling Drug Delivery 239Stefano Giovagnoli, Aurélie Schoubben and Carlo Rossi 12.1 Introduction 239 12.2 Ion Pairing Definitions and Concepts 240 12.3 Ion Pairs, Complexes and Drug Delivery 245 12.4 Remarks 252 References 254 13 Understanding the Respiratory Delivery of High Dose Anti-Tubercular Drugs 258Shyamal C. Das and Peter J. Stewart 13.1 Introduction 258 13.2 Tuberculosis 259 13.3 Drugs Used to Treat Tuberculosis, Doses, Challenges and Requirements for Therapy in Lungs 260 13.4 Approaches for Respiratory Delivery of Drugs 262 13.5 Current DPI Formulations and Their Mechanisms of Aerosolization 262 13.6 DPI Formulations for Tuberculosis and Requirements 264 13.7 Issues to Consider in Respiratory Delivery of Powders for Tuberculosis 264 13.8 Relationship between De-agglomeration and Tensile Strength 266 13.9 Strategies to Improve De-agglomeration 268 13.10 DPI Formulations having High Aerosolization 269 13.11 Devices for High Dose Delivery 270 13.12 Future Considerations 271 References 272 Section 4 Alternative Approaches 275 14 Respirable Bacteriophage Aerosols for the Prevention and Treatment of Tuberculosis 277Graham F. Hatfull and Reinhard Vehring 14.1 Introduction 277 14.2 Treatment or Prevention of Tuberculosis Using Phage-based Agents 282 14.3 Selection of Mycobacteriophages 284 14.4 Respiratory Drug Delivery of Phages 285 14.5 Summary and Outlook 288 Acknowledgements 288 References 288 15 RNA Nanoparticles as Potential Vaccines 293Robert DeLong 15.1 Introduction 293 15.2 Nanoparticles 293 15.3 RNA Nanoparticle Vaccines 294 15.4 Progression of Nanomedicines into the Clinic 295 15.5 The Stability Problem 295 15.6 The Delivery Problem 298 15.7 RNA as Targeting Agent or Adjuvant? 298 15.8 Challenges for RNA Nanoparticle Vaccine Characterization 300 15.9 On the Horizon 301 References 301 16 Local Pulmonary Host-Directed Therapies for Tuberculosis via Aerosol Delivery 307Mercedes Gonzalez-Juarrero 16.1 Introduction 307 16.2 Lung Immunity to Pulmonary M. tuberculosis Infection 309 16.3 Host-Directed Therapies 313 16.4 Limitations of Preclinical Studies to Develop Inhalational Host-Directed Therapies for Tuberculosis 317 16.5 Preclinical Testing of Inhaled Small Interference RNA as Host-Directed Therapies for Tuberculosis 318 Acknowledgements 319 References 319 Section 5 Future Opportunities 325 17 Treatments for Mycobacterial Persistence and Biofilm Growth 327David L. Hava and Jean C. Sung 17.1 Introduction 327 17.2 Mycobacterial Persistence and Drug Tolerance 328 17.3 Mycobacterial Multicellular Growth 329 17.4 Mycobacterial Lipids Involved in Biofilm Formation 330 17.5 Therapies to Treat Mycobacterial Biofilms and Persistence 332 17.6 Conclusion 339 References 339 18 Directed Intervention and Immunomodulation against Pulmonary Tuberculosis 346Dominique N. Price and Pavan Muttil 18.1 Introduction 346 18.2 TB Immunology 347 18.3 Animal Models of Immunotherapies and Vaccines for TB 351 18.4 The Current TB Vaccine – Bacille Calmette Guérin 353 18.5 Other Vaccines Platforms 357 18.6 Pulmonary Immunization 361 18.7 Immunotherapeutic Agents against TB 364 18.8 Conclusion 367 References 367 Section 6 Clinical Perspective 379 19 Clinical and Public Health Perspectives 381Ruvandhi R. Nathavitharana and Edward A. Nardell 19.1 Introduction 381 19.2 Background 382 19.3 Clinical Considerations 382 19.4 Public Health Considerations 385 19.5 Inhaled Drugs and Other Alternative Delivery Systems 387 19.6 Clinical Trials of Inhaled Injectable Drugs 388 19.7 Other Novel Delivery Strategies 393 19.8 Pediatric Delivery Systems 393 19.9 Conclusion 394 References 394 20 Concluding Remarks: Prospects and Challenges for Advancing New Drug and Vaccine Delivery Systems into Clinical Application 400P. Bernard Fourie and Richard Hafner 20.1 Introduction 400 20.2 Progress in the Formulation and Manufacturing of Drugs and Vaccines for Tuberculosis 401 20.3 Considerations in the Development of TB Drug and Vaccine Delivery Options 404 20.4 Concluding Remarks 410 References 411 Index 415
£124.40
John Wiley and Sons Ltd Respiratory Nursing at a Glance
Book SynopsisFrom the publishers of the market leading at a Glance series, and in collaboration with the Association of Respiratory Nurses (ARNS), comes this easy-to-read, highly visual guide bringing together key principles of Respiratory Nursing.Trade ReviewThis text presents information on respiratory conditions in a succinct manner, beginning with an overview of the historical context of respiratory nursing and moving on to discuss anatomy and physiology, epidemiology, exercise, nutrition and pulmonary rehabilitation.There are two particularly good chapters that summarise history-taking and physical assessment, which are skills that nurses are increasinglyexpected to have......The book has a strong nursing focus and provides an excellent overview of the topic. It would be suitable for newly-qualified staff and those with more experience, such as clinical nurse specialists and ward managers. (Nursing Standard- December 2016)Table of ContentsContributors vii Preface viii About ARNS ix Part 1 The context of respiratory nursing 1 1 The origins of respiratory nursing 2 2 Working in secondary care 4 3 Working in primary care 5 4 Ambulatory, intermediate and tertiary care 6 5 The future of respiratory nursing 7 6 Respiratory public health 8 Part 2 Respiratory health 11 7 The respiratory system 12 8 Preventing respiratory disease 14 9 Epidemiology and contributing factors 16 10 Smoking and smoking cessation 18 11 Exercise and pulmonary rehabilitation 20 12 Nutrition and hydration 22 13 The upper airways 24 14 Respiratory disease and sexuality 26 Part 3 Assessment and diagnosis of respiratory disease 29 15 Respiratory history taking 30 16 Respiratory clinical examination 32 17 Measuring dyspnoea 34 18 Sputum assessment 36 19 Pulse oximetry 38 20 Blood gas sampling and analysis 40 21 Spirometry 42 22 Measuring quality in healthcare 44 23 Assessing anxiety and depression 46 Part 4 Respiratory diseases 49 24 Asthma 50 25 Chronic obstructive pulmonary disease 52 26 Pleural disease 54 27 Lung cancer 56 28 Obstructive sleep apnoea syndrome 58 29 Acute respiratory infections 60 30 Cystic fibrosis 62 31 Bronchiectasis 64 32 Occupational and environmental lung disease 66 33 Interstitial lung disease 68 34 Sarcoidosis 70 35 Pulmonary tuberculosis 72 36 Venous thromboembolism and pulmonary embolism 74 37 HIV and respiratory disease 76 Part 5 Models of care 79 38 Care pathways and care bundles 80 39 Self-management in chronic respiratory disease 82 40 Telemedicine and telehealth 84 41 Patient education 86 42 Voluntary organisations and patient support groups 88 Part 6 Respiratory medication 91 43 Pharmacology and prescribing 92 44 Inhaler technique 94 45 Nebuliser therapy 96 46 Emergency oxygen therapy 98 47 Domiciliary oxygen therapy 100 48 Other routes of administration 102 49 Adherence and concordance 103 Part 7 Acute care of the respiratory patient 105 50 Respiratory failure 106 51 Pre-hospital care 108 52 Non-invasive and invasive ventilation 110 53 Pleural procedures and management 112 54 Tracheostomy care and management 114 Part 8 Supportive and palliative care 117 55 Communication 118 56 Psychosocial impact of respiratory disease 120 57 Management of dyspnoea 122 58 Anxiety and depression in respiratory disease 124 59 Other symptom management 126 60 NIV as a domiciliary therapy 128 61 End-of-life care 130 62 Families and carers 132 References 134 Index 139
£30.35
Taylor & Francis Ltd Applied Respiratory Pathophysiology
Book SynopsisThis easy yet comprehensive reference guide covers the mechanisms of respiratory diseases, explaining the main respiratory conditions for clinicians and postgraduate trainees. It discusses their aetiology as well as the basic concepts required to effectively evaluate and treat them. Applied Respiratory Pathophysiology is the first book to bring together detailed, clinically-relevant explanation of respiratory physiological processes and pathophysiological processes in one text. It is essential reading for anyone diagnosing and treating specific clinical conditions of the lungs.Table of ContentsCHAPTER 1. EMBRYOLOGY, ANATOMY AND HISTOLOGY OF THE LUNGCHAPTER 2. PHYSIOLOGY OF THE RESPIRATORY SYSTEMCHAPTER 3. LABORATORY TECHNIQUES TO STUDY THE CELLULAR AND MOLECULAR PROCESSES OF DISORDERSCHAPTER 4. ACUTE RESPIRATORY INSUFFICIENCYCHAPTER 5. PATHOPHYSIOLOGY OF ASTHMACHAPTER 6. CHRONIC OBSTRUCTIVE PULMONARY DISEASECHAPTER 7. PULMONARY VASCULAR DISEASES CHAPTER 8. RESPIRATORY INFECTIONSCHAPTER 9. SLEEPING RESPIRATORY DISEASESCHAPTER 10. INTERSTITIAL LUNG DISEASESCHAPTER 11. LUNG CANCERCHAPTER 12. OCCUPATIONAL RESPIRATORY DISEASESCHAPTER 13. DISEASES OF THE PLEURACHAPTER 14. CYSTIC FIBROSISCHAPTER 15. BRONCHIECTASIS
£133.00
Taylor & Francis Ltd Nursing Skills in Cardiorespiratory Assessment and Monitoring
Organisms need to be able to maintain nearly constant internal environments in order to survive, grow and function effectively and efficiently. By maintaining homeostasis, humans remain healthy, strong and protected from the invasion of foreign organisms, such as viruses, bacteria and fungi. This practical pocket guide covers: the anatomy and physiology of cardiovascular system vital signs recognition of common arrhythmias and important skills for cardiovascular health cannulation and venepuncture the anatomy and physiology of the respiratory system skills related to addressing respiratory problems.This competency-based text covers relevant key concepts, anatomy and physiology, lifespan matters, assessment and nursing skills. To support your learning, it also includes learning outcomes, concept map summaries, activities, questions and scenarios with sample answers and critical reflection thinking points.Quick and easy to reference, this shor
£13.99
Taylor & Francis Ltd Complete Guide to Respiratory Care in Athletes
Book Synopsis Complete Guide to Respiratory Care in Athletes introduces the respiratory system and its function during exercise. It considers the main respiratory conditions affecting athletes and delivers practical advice for the management of respiratory issues in athletic populations.With contributions from leading international experts, the book discusses fundamental scientific principles and provides pragmatic hands-on' clinical guidance to enable practical application. Each chapter includes useful pedagogical features such as case studies and guides for carrying out assessments. The book covers wide a range of topics, including: respiratory system function during exercise impact of the environment on the upper and lower airways asthma related issues in athletes allergic rhinitis in athletes exercise induced laryngeal obstruction exercise induced dysfunctional breathing paterns respiratory muscle traiTable of Contents1. The Respiratory System and Exercise 2. Respiratory Limitations to Exercise 3. The Environment and Its Impact on Respiratory Health 4. Epidemiology and Pathophysiology of Exercise-Induced Bronchoconstriction in Athletes 5. Diagnosis of Exercise-Induced Bronchoconstriction 6. Pharmacological Treatment of Asthma Related Issues in Athletes 7. Non-Pharmacological Management of Asthma Related Issues in Athletes 8. Nasal Problems in the Athlete 9. Exercise-induced laryngeal obstruction 10. Dealing with Respiratory Infection in Athletes 11. Breathing Pattern Disorders in Athletes 12. Role of Respiratory Muscle Training to Treat Exercise Respiratory Symptoms 13. Epilogue: Optimising Care for Respiratory issues in Athletes
£36.09
John Wiley & Sons Lung Cancer Your Questions Expert Answers
Book Synopsis
£17.09
John Wiley & Sons Respiratory Critical Care
Book Synopsis
£90.90
Jones and Bartlett Publishers, Inc Equipment for Respiratory Care
Book Synopsis
£67.15
Jones and Bartlett Publishers, Inc BU Malcolm X College Respiratory Care Print
Book Synopsis
£412.19
WW Norton & Co Breathing Lessons
Book SynopsisAn authoritative, accessible guide to how our lungs work and how to protect themTrade Review"A comprehensive guide to lung structure, without seeming too daunting to a layman reader…[Han's] call pulmonary education could not have come at a better time." -- Bri Paterson - The Lancet"Breathing is essential to life, yet historically, the lungs haven’t received as much attention as other organs of the body. Especially as our world faces the intersecting health threats of COVID-19, chronic lung diseases, and air pollution, Breathing Lessons is an imperative and engaging read for all those who breathe." -- Harold Wimmer, President and CEO, American Lung Association
£13.29
Hay House Inc The Breathable Body
Book SynopsisTrade ReviewThis loving book comes from the heart of love of a daring explorer of the mysteries of the body. Open anywhere and be reminded how delicious it can be to simply take a breath. - Lorin Roche, Ph.D., author of The Radiance Sutras: 112 Gateways to the Yoga of Wonder and Delight and Meditation Made EasyIf I had to choose among the many books on breath and breathing, The Breathable Body is without question the one I would choose. While clarifying the anatomy, physiology, chemistry, and mechanics of breathing, Litman shows how breathing is a whole-body phenomenon of our dynamic, fluid organism. His depth and breadth of knowledge are present in each explanation and exploration, and if you are one of the millions suffering from a breathing, sleep, or anxiety disorder, chances are the information you need is in this book. - Don St John, Ph.D., author of Healing the Wounds of Childhood and Culture: An Adventure of a LifetimeRobert Litman shows how you can change your health, your mood, and your connection to all of life by changing how you breathe. Whether you struggle with breathing, need effective strategies for self-regulation, or want to more fully enjoy the pleasures of being alive, this book will provide insight and solutions to some surprisingly common health conditions. The Breathable Body is an essential tool for good health! - Sharon Weil, Registered Somatic Movement Educator, author of ChangeAbility: How Artists, Activists and Awakeners Navigate ChangeLitman draws on more than three decades of experience working with clients to bring together a resource accessible to everyone. What sets The Breathable Bodyapart is the connection it highlights between body and breath, and how breathing and movement are linked. Your doctor may not have told you about the benefits of breathing re-education. The Breathable Body does just that! If you breathe, this book is for you. - Patrick McKeown, Director of Education and Training at Buteyko Clinic International and author of The Oxygen AdvantageRobert provides a well-crafted paeon to the sacred and healing act of breathing; it is anatomy as poetry, required reading for anyone interested in the healing aspects of conscious breathing. - Karen M Gardner, PhD in Information Science, UC BerkeleyCombining memoir, breathing therapy, and inquiry into the dynamic movement of body and mind, The Breathable Body offers deep insights and practical instructions on every page. This is a highly relatable book you’ll return to again and again for sagely advice. - Matteo Pistono, author of Meditation: Coming to Know Your Mind and In the Shadow of the BuddhaRobert delivers a message in The Breathable Body that has the potential to not only improve your health but also enhance the quality of your life. He has managed to bridge the gap between cognitive understanding of the scientific knowledge of breathing processes while guiding his readers into an immediate somatic participation with the material. This book offers a transmission of intimate presence with oneself and a reminder that the sacred resides in the present moment. - Gael Rosewood, Continuum teacher, certified Rolfer, and CE teacher and mentor for both modalitiesConscious breathing has become a psychospiritual and energy-medicine meme, popularized in bodywork, yoga, and meditation circles to a degree that makes breathing so hyperconsciously conscious that it becomes even more unconscious. It takes a breath practitioner who has been through its many layers of morphogenesis, phenomenology, dynamic function, micromovement, and personal unlayering to teach you how to make your breathing more endurably conscious. Robert Litman is a true breath healer, explorer, and teacher. - Richard Grossinger, author of Bottoming Out the Universe and Dreamtimes and ThoughtformsRobert draws you into the world of breath like nothing I've read before! Whether you are looking for help for an ailment or want to enrich your life through breath, this book—steeped with rich resources to expand and explore breathing—is for you. - Bobbie Ellis, Continuum teacher and 500+ Experienced Registered Yoga TeacherRobert Litman takes us on a psychological journey, leading us through his own history with breathing and the metaphor for life that it has come to hold for him. Based on his hard-won wisdom, he guides us in practical ways that have helped so many—how to bring conscious breathing meaningfully into our lives. - Peter M. Litchfield, President, Graduate School of Behavioral Health Sciences, lecturer in respiratory psychophysiology, self-regulation science, and many other subjectsBreath spirals, listens, touches us on the inside, responds to kindness, tenderness, compassion, and gentleness, whispering its wildness into us. Others teach the science of breath, measuring and counting. Robert transmits the art and flow, letting breath lead us into the unknown. The Breathable Body offers a glimpse into the author’s love affair with breath, a quiet transmission into the most profound relationship we have. What a treasure this book is! - Roxanne Rhodes, Certified Yoga Instructor, Trager practitioner, and massage therapist
£15.29
John Wiley and Sons Ltd Lung Cancer
Book SynopsisLung Cancer: A Multidisciplinary Approach provides clinicians with a comprehensive text that can be used when caring for patients with lung cancer throughout the entire patient journey. This edited collection explores the aetiology of lung cancer; mesothelioma; the range of available treatments, including chemotherapy and radiotherapy; surgical care; supportive and end-of-life care; quality-of-life issues; and the role of the nurse within the multidisciplinary team. A comprehensive, evidence-based guide to lung cancer Illustrative case studies used throughout Contributions from respected healthcare professionals in the field Interprofessional in focus Lung Cancer: A Multidisciplinary Approach is an essential resource for all nurses and healthcare professionals working with cancer patients.Trade Review“This is a superb book that includes a huge amount of relevant and up-to-date information without appearing to be cumbersome. It will be invaluable to all healthcare professionals caring for patients with lung cancer.” (Nursing Standard, 1 February 2013) “This well-written book can be quite useful as a resource for RNs and other healthcare professionals caring for lung cancer patients.” (Doody's, 3 August 2012) “I recommend this volume as a resource for students, staff new to the field and qualified professionals. It provides a comprehensive overview of the main issues faced by patients diagnosed with this aggressive disease.” (Cancer Nursing Practice, 1 June 2012)Table of ContentsContributors ix Acknowledgements xi 1 Introduction to Lung Cancer and Mesothelioma 1 Alison Leary Introduction 1 Epidemiology and causes of lung cancer 2 Overview of the types of lung cancer 6 Delivering cancer services and the multidisciplinary team 8 Meeting information needs 11 Summary 13 References 13 2 The Presentation and Diagnosis of Lung Cancer and Mesothelioma 15 Neal Navani and Stephen G. Spiro Introduction 15 Clinical features of lung cancer 17 Paraneoplastic syndromes 22 Risk factors for lung cancer 26 Performance status 27 Investigation of lung cancer 28 Staging of lung cancer 38 An algorithm for the diagnosis and staging of non-small-cell lung cancer 41 Mesothelioma 42 Summary 46 References 46 Further reading 47 3 Chemotherapy and Biological Agents 49 Fharat A. Raja and Siow Ming Lee Introduction 49 Chemotherapy 50 Chemotherapy for advanced NSCLC 53 Addition of targeted therapies to chemotherapy in NSCLC 55 Chemotherapy for small-cell lung cancer 57 Mesothelioma 59 Summary 61 References 61 4 Lung Radiotherapy 65 Nita Patel and Dawn Carnell Introduction 65 Principles of radiotherapy 65 The use of radiotherapy in non-small-cell lung cancer 73 The use of radiotherapy in small-cell lung cancer 76 Palliative radiotherapy 78 Management of patients during radiotherapy 80 New techniques under evaluation 83 Summary 84 References 84 5 Surgery for Lung Cancer 87 Neil Cartwright and Aman S. Coonar Introduction 87 The role of the surgeon 89 Reaching decisions about surgery 90 Surgery for cancers of the lung 100 The role of adjuvant treatment in NSCLC 108 Palliative surgical procedures 110 Carcinoid tumours and neuroendocrine cancer 111 Surgery for small-cell lung cancer 112 Bronchoalveolar cell cancer 112 Postoperative complications, rehabilitation follow-up 112 The multidisciplinary team in postsurgical care 115 Summary 116 References 116 6 The Nursing Care of Patients with Lung Cancer 121 Sally Moore Introduction 121 What are the important issues in relation to lung cancer nursing? 122 Context of lung cancer services 123 The challenges of lung cancer 124 The role of the specialist nurse 138 Summary 139 References 139 7 Supportive Care in Lung Cancer 145 Kay Eaton Introduction 145 Supportive care 146 Communicating the 'diagnosis' 147 Attitudes towards cancer 148 Uncertainty 149 Psychological distress 150 A family-centred approach to care 152 Improving the patient experience: care across the pathway 153 Summary 156 References 156 8 End of Life Care 159 Michael Coughlan Introduction 159 Palliative and end of life care 159 Dying in the twenty-first century 160 Diagnosing dying 162 Managing complex ethical dilemmas 163 Planning care for the patient dying from lung cancer 164 Summary 181 References 182 9 Quality of Life in Lung Cancer 189 Alison Leary Introduction 189 Cancer: the journey, the individual and society 190 Doing the work of cancer and quality of life 192 Towards an understanding of the meaning of quality of life in lung cancer 192 Quality of life in advanced lung cancer: instruments used to measure health-related quality of life 197 Summary 199 References 199 Index 203
£35.06
John Wiley and Sons Ltd Childrens Respiratory Nursing
Book Synopsis* Examples of good practice provided throughout * Includes evidence-based case studies * Explores care in both hospital and community settings * A strong practical approach throughout .Trade Review“As such it makes an excellent starting point and source of reference for those involved in nursing children and young people.” (Nursing Times, 21 January 2014) “Reasonably priced, this is a useful book to refer to and might prove valuable for children’s nurses working in hospitals and in the community.” (Nursing Children and Young People, 1 March 2013) Table of ContentsContributors vii Foreword by Preface xi Acknowledgements xiii Introduction: the evolution of children’s respiratory nursing 1 Angela Horsley, Clinical Lead, Nottingham Children’s Hospital ix Janice Mighten Section I The fundamental principles of respiratory nursing 3 1 Anatomy and physiology of the respiratory system 5 Conrad Bosman 2 Homeostasis and the respiratory system 11 Andrew Prayle 3 Nursing assessment, history taking and collaborative working 16 Janice Mighten Section II Respiratory investigations and assessments 25 4 Investigations 27 Alan R. Smyth, Conrad Bosman and Janice Mighten 5 Assessment of defects in airflow and lung volume using spirometry 41 Harish Vyas and Caroline Youle 6 Oxygen therapy 55 Jayesh Bhatt and Sarah Spencer 7 Long-term ventilation 73 David Thomas and Beverley Waithe Section III Respiratory conditions 89 8 Management of lung infection in children 91 Alan R. Smyth 9 Pharmacology and the respiratory system 107 Andrew Prayle and Janice Mighten 10 Management of asthma and allergy 113 Jayesh Bhatt, Harish Vyas and Debra Forster 11 Complications with lung development and progressive airway injury 134 Jayesh Bhatt, Chhavi Goel and Sarah Spencer 12 Inherited lung disease in children 156 Alan R. Smyth, Ammani Prasad and Janice Mighten 13 Lung transplantation in children 186 Helen Spencer and Katherine Carter Section IV Practical elements and governance issues 207 14 Transition to adult services 209 Donna Hilton 15 Professional issues 215 Janice Mighten 16 Communication: a holistic approach 224 Phil Brewin Glossary 238 Abbreviations 240 Answers 243 Index 248
£45.55
Cengage Learning, Inc Basic Clinical Lab Competencies for Respiratory
Book SynopsisA book on Basic Clincial Lab Competencies for Respiratory Care.Table of ContentsTOCS not yet available
£149.48
Bloomsbury Publishing Plc What You Need to Know about Asthma
Book SynopsisWhile some individuals with asthma consider the condition only a minor nuisance, for others it significantly interferes with daily activities and may even be life-threatening. This book offers readers a broad introduction to this common respiratory issue.Asthma is a respiratory condition marked by spasms, swelling, and excess mucus production in the bronchial passages of the lungs. This triggers coughing, wheezing, chest tightness, and shortness of breath. While asthma can usually be managed with medications and avoidance of certain triggers, it''s a seriouspotentially deadlychronic disease.What You Need to Know about Asthma is part of Greenwood''s Inside Diseases and Disorders series. This series profiles a variety of physical and psychological conditions, distilling and consolidating vast collections of scientific knowledge into concise, readable volumes. A list of top 10 essential questions begins each book, providing quick-access answers to readers'' most pressing conTrade ReviewAn excellent and concise, yet clear and comprehensive, overview of a common disease. Should benefit new and longtime asthma patients, their parents and other relatives, and school personnel. * Library Journal *Table of ContentsSeries Foreword Acknowledgments Introduction Essential Questions Chapter 1 What Is Asthma? Chapter 2 The History of Asthma Chapter 3 Causes and Risk Factors Chapter 4 Signs and Symptoms Chapter 5 Diagnosis, Treatment, and Management Chapter 6 Long-Term Prognosis and Potential Complications Chapter 7 Effects on Family and Friends Chapter 8 Prevention Chapter 9 Issues and Controversies Chapter 10 Current Research and Future Directions Case Studies Glossary Directory of Resources Bibliography Index
£41.02
Taylor & Francis Ltd Practical Rhinology
Book SynopsisAn ideal textbook for trainee and practising rhinologists and otolaryngologists, Practical Rhinology provides expert direction on all aspects of rhinology. This up-to-date text addresses the most pertinent aspects of contemporary rhinology and provides a distillation of the current advances in this superspecialty from several of the world''s leaders in the field. Designed to help the clinician during day-to-day practice, the book emphasizes clinical management and focuses on the most common disorders and symptoms.General chapters on anatomy, pre- and post-operative management and complications are accompanied by skilled guidance on how to address specific surgical problems, such as anterior skull base surgery, the frontal sinus, and nasal tumours. Additional chapters provide invaluable information on technical advances, paediatric conditions, CSF leaks, and orbital and lacrimal surgery. Chapters on how to interpret symptoms and the patient''s perspeTrade ReviewAn ideal textbook for trainee and practising rhinologists and otolaryngologists, Practical Rhinology provides expert direction on all aspects of rhinology. Completely up-to-date, the text addresses the most pertinent aspects of contemporary rhinology and provides a distillation of the current advances in this superspecialty from several of the world's leaders in this field.—Doody's Core TitlesTable of ContentsApplied surgical anatomy of the nasal cavity and paranasal sinuses. Making sense of symptoms. Medical management of rhinosinusitis. Technical advances and the endoscopically assisted bimanual technique. Preoperative work-up and assessment. Complications of sinus surgery. Orbital and lacrimal surgery. Endonasal surgery of the anterior skull base. Pituitary and parasellar surgery. Endoscopic management of nasal tumours. Cerebrospinal fluid leaks. The frontal sinus. The posterior ethmoid cells and sphenoid sinus. Management of recalcitrant sinusitis, including allergic fungal sinusitis and Samter’s triad. What is new in managing the maxillary sinus? Paediatric issues in sinus surgery. Sinus surgery and olfaction in chronic rhinosinusitis. Postoperative management. Helping patients. Case studies.
£190.00
Taylor & Francis Inc Clinical Asthma
Book SynopsisEnormous progress in asthma research has been made in the past 50 years, including a greater understanding of its complex pathogenesis and new and more effective therapies. Consequently, the scientific literature has grown vast and can be difficult to integrate. With contributions from a distinguished panel of world-renowned authors, Clinical Asthma: Theory and Practice presents a comprehensive study of both the common and the more challenging problems faced by all health care personnel who treat patients with asthma. The book is divided into seven sections, starting with the basics of asthma and ending with a discussion on the approach to asthma worldwide and in the primary care setting. Reflecting a strong clinical emphasis, each chapter begins with a patient case study supported by essential background information on the basic science and clinical decision-making process. This is followed by a discussion of clinical evaluation and management. ThTrade Review"…if you want to learn more about asthma in reasonable depth then this is a good port of call. It is reasonably detailed and its main thrust is clinical … I’m sure once a healthcare professional is finished reading it, then they will be far more knowledgeable in this condition."—Dr. Harry Brown Table of ContentsThe Basics of Asthma. Epidemiology of Asthma: A Worldwide Perspective. Immunopathogenesis. Genetics and Asthma. Endotypes and Asthma. Diagnosis of Asthma. Guidelines in Asthma. Diagnosis of Asthma in Preschool-Age Children. Diagnosis of Asthma in Older Children and Adults. United Airways: Managing Patients with Allergic Rhinitis and Asthma. Asthma Triggers. Viral Infections in Asthma. Asthma and Allergens. Air Pollutants. Exercise-Induced Bronchoconstriction. Asthma Education and Outcomes. Asthma Education. Adherence and Outcomes. Inhaler Devices. Assessment of Asthma Control in Adults. Asthma Management and Treatments. Management of Pediatric Asthma. Management of Adolescent Asthma. Management of Adult Asthma. Management of Asthma in Older Adults. Severe Acute and Life-Threatening Asthma in Children. Severe Acute and Life-Threatening Asthma in Adults. Asthma and Special Populations. Asthma and Obesity: Clinical Implications. Occupational Asthma. Asthma in Pregnancy. Anxiety and Depression and Asthma. Approach to Asthma Worldwide and in the Primary Care Setting. Managing Asthma and Allergy: A Countrywide Approach to Integrating Care. Primary Care Setting and Integrating Care across Primary/Secondary Care Interface. Preventing Asthma Death: Primary Care Setting. Index.
£161.50
Taylor & Francis Inc Lung Transplantation
Book SynopsisLung Transplantation: Principles and Practice covers the current practice in donor and recipient management as well as current treatment strategies and outcomes. With 39 chapters from international experts in the field, the book is divided into four broad sections: General Topics, Donor Management, Recipient Management and Outcome, and the Future of Lung Transplantation. The book discusses significant advances achieved in the past decade in areas such as donor allocation, organ preservation and management, recipient selection, management and support, surgical and critical care techniques, immune suppression, and infection prophylaxis. Specific instances of pulmonary disease that commonly necessitate lung transplantation are also covered. Generously illustrated in full color, this valuable resource is relevant to both specialists and other providers who may refer or care for patients before and after transplantation. Trade Review"This thorough review of lung transplantation covers in detail all aspects, providing an excellent resource for all health professionals involved in this field. The accompanying ebook can be accessed using different platforms (PC, iPad, Kindle, etc.) and provides tools to easily find chapters, figures, and references… This is one of the most complete resources on lung transplantation and it provides a wealth of information that is easy to access via the online version." - Reinaldo Rampolla, MD(Ochsner Medical Center), Doody's Book Review ServiceTable of ContentsGENERAL TOPICS. History of Lung Transplantation. Immunology of Lung Transplantation. Ethical Considerations in Transplantation: A Focus on Lung Transplantation. Indications for Lung Transplantation and Patient Selection. Recipient Management before Transplantation. DONOR MANAGEMENT. Allocation of Donor Lungs. Donor Selection and Management. Non-Heart-Beating Donors. Donor Lung Preservation. Donor Procurement. Ex Vivo Lung Perfusion. RECIPIENT MANAGEMENT AND OUTCOME. The Humoral Response to Lung Transplantation. Anesthesia for Lung Transplantation. Mechanical Ventilation and Extracorporeal Membrane Oxygenation (ECMO) Bridges to Lung Transplantation. Single-Lung Transplantation: Technical Aspects. Bilateral Sequential Lung Transplantation: Technical Aspects. Heart-Lung Transplantation: Technical Aspects. Lobar Lung Transplantation from Living Donors: Technical Aspects. Technical Aspects of Redo Lung Transplantation and Lung Transplantation after Previous Thoracotomy. Lung Transplantation for Idiopathic Pulmonary Fibrosis. Lung Transplantation for Emphysema and α1-antitrypsin Deficiency. Lung Transplantation for Cystic Fibrosis and Bronchiectasis. Lung Transplantation for Pulmonary Hypertension. Lung Transplantation for Connective Tissue Disorders. Posttransplantation Critical Care Management. Primary Graft Dysfunction. Management of Surgical Complications. Immunosuppression Strategies in Lung Transplantation. Viral Infections in Lung Transplantation. Fungal Infections in Lung Transplantation. Bacterial Infections after Lung Transplantation. Diagnosis of Lung Rejection and Infection: A Pathologist’s Perspective. Obliterative Bronchiolitis/Bronchiolitis Obliterans Syndrome: Etiology, Diagnosis, and Management. Chronic Lung Allograft Dysfunction Other Than Bronchiolitis Obliterans Syndrome. Medical Complications of Lung Transplantation. Malignancy Following Lung Transplantation. Quality of Life Following Lung Transplantation. FUTURE OF LUNG TRANSPLANTATION. Future Therapies in Lung Transplantation. New Horizons in Lung Transplantation.
£194.75
Taylor & Francis Inc The Health Effects of Asbestos
Book SynopsisThe health-related effects of asbestos have long been mired in controversy, with industry and plaintiff attorneys playing a significant role. This comprehensive book provides a balanced and extensive evidence-based critical analysis of the literature concerning asbestos-related diseases, from a scientific and historical perspective. The book presents a carefully referenced review of the medical literature on the health effects of asbestos, and reflects the extensive experience of the author in evaluating patients with asbestos-related disorders.Trade Review"What Dr. Smith outlines as an evidence-based approach is likely as relevant to other key toxic materials as it is to asbestos. His first chapter, devoted to reading and finding truth in the medical scientific literature, is instructive in many fields. An understanding of the health effects of asbestos has remained as refractory as the mineral itself. I'll return to these pages many times, as much to understand how we have proceeded, as to review the specific health-related effects of asbestos." - J. Thomas Pierce, MBBS PhD (Navy Environmental Health Center)Table of ContentsHow to Critically Read and Find Truth in the Medical Scientific Literature. Limitations of Epidemiologic Exposure Studies on the Health. Clinical Toxicology of Asbestos. History of Asbestos Commercial Use and Discovery of Adverse Health Effects: Asbestosis. What Is Asbestosis and What Is Not: Radiology and Pathology Correlates the Association of Lung Cancer and Asbestosis. The Effect of Smoking and Lung Cancer. Asbestos-Related Pleural Disease. Disability and Impairment in Asbestosis and Asbestos-Related Diffuse Pleural Disease. The Evolution of Workers’ Compensation and Employer Responsibility. Does Asbestos Cause Additional Malignancies Other than Lung Cancer and Mesothelioma? Asbestos Exposure and Mesothelioma. The Many Causes of Mesothelioma. Other Causes of Mesothelioma Not Related to Asbestiform Mineral Fibers. Mesothelioma and Asbestos Fiber Type. Chrysotile and Mesothelioma. The Tremolite Hypothesis. Mesothelioma Latency and Risk Risk Modeling. Household and Neighborhood Exposure to Asbestos. What Did Asbestos Pipe insulation Manufacturers and the U.S. Navy Understand About the Risk to Manufacturing Employees and End Users? The intervention of Government to Provide Safety Standards NIOSH/ACGIH Standards. Is there a Safe Or Risk-Free Level of Asbestos Exposure? How Do We Define Risk?
£161.50
Taylor & Francis Inc Asthma COPD and Overlap
Book SynopsisUsing illustrative case examples, this book thoroughly reviews similarities and differences between asthma, chronic obstructive pulmonary disease (COPD) and the overlap syndrome. It is important to highlight the distinctions because these commonly encountered conditions in respiratory and primary care share many similarities but have important differences often mistaken for each other. This can have serious implications for treatment, particularly as new treatments are targeted at specific phenotypes of the diseases. This practical guide shows how to distinguish between the diseases on a pathological and clinical basis so that appropriate management and treatment may be pursued. Table of ContentsDefinitions and Pathophysiology. Definitions of Asthma and COPD and overlap syndrome. Epidemiology. Genetics. Histopathology. Physiology. Mechanisms. Environmental Exposures and Triggers. Tobacco-active and passive smoke exposure. Indoor and outdoor pollutants and allergens. The role of infection in asthma and COPD (microbiomes). Exercise. Diagnosis. Differential Diagnosis: Diseases mimicking or complicating asthma and COPD. Phenotypes and Endotypes. Occupational lung diseases. Special populations. History and Physical Examination. Diagnostic Testing. Treatment. Environmental control. Medications. Biologics and emerging therapies. Invasive treatments. Oxygen therapy, pulmonary hygiene and pulmonary rehabilitation. Smoking cessation. Unmet needs and promising therapies. Management. Treatment of acute exacerbations. Approach to chronic management. Prognosis and Outcomes. Outcomes and quality
£74.09
University of Minnesota Press Breathtaking: Asthma Care in a Time of Climate
Book SynopsisAnalyzing asthma care in the twenty-first centuryAsthma is not a new problem, but today the disease is being reshaped by changing ecologies, healthcare systems, medical sciences, and built environments. A global epidemic, asthma (and our efforts to control it) demands an analysis attentive to its complexity, its contextual nature, and the care practices that emerge from both. At once clearly written and theoretically insightful, Breathtaking provides a sweeping ethnographic account of asthma’s many dimensions through the lived experiences of people who suffer from disordered breathing, as well as by considering their support networks, from secondary school teachers and coaches, to breathing educators and new smartphone applications designed for asthma control. Against the backdrop of unbreathable environments, Alison Kenner describes five modes of care that illustrate how asthma is addressed across different sociocultural scales. These modes of care often work in combination, building from or preceding one another. Tensions also exist between them, a point reflected by Kenner’s description of the structural conditions and material rhythms that shape everyday breathing, chronic disease, and our surrounding environments. She argues that new modes of distributed, collective care practices are needed to address asthma as a critical public health issue in the time of climate change.Trade Review"This elegant first monograph from the Asthma Files Project is written simply for all audiences and provides five practical recommendations. Breathtaking is social science at its best: experiential, explanatory, critical, and providing ways forward. Alison Kenner herself is an active participant as community social-scientist and as partner to someone who suffers disordered breathing. She guides us vividly across scales and registers."—Michael M.J. Fischer, author of Anthropology in the Meantime"Breathtaking is a sweeping ethnographic account of asthma and its treatments that expertly traverses questions of lived experience, medical technology, and critical ecology as they bear on the epidemic of disordered breathing. Beautifully written and poignant, this book makes a robust contribution to our understanding of the health effects of environmental degradation and climate change, deepens the critiques of biomedicalization, and heralds the promise of complementary and alternative medicine."—Anthony Ryan Hatch, author of Blood Sugar"Breathtaking is an engrossing read."—CHOICE"Breathtaking presents a compelling and very readable ethnographic overview of the ways that asthma is grappled with across a variety of 21st century American contexts. This book offers an insightful and multi-faceted account of a condition that affects so many around the world."—Somatosphere"Overall, Breathtaking takes asthma from the biomedical world, and using a multi-sited ethnography, traces connections between the experience of asthma, the environment and our bodies, allowing us to imagine new carescapes that could make the world more breathable."—LSE Review of Books"In the absence of swift and uncompromising action on the part of US legislators to combat climate change, Kenner advocates democratizing access to affordable health care; integrating breathing training into the doctor’s toolkit; and enacting policy, at all levels of government, to improve the indoor environments in which we spend the majority of our time."—H-EnvironmentTable of ContentsIntroduction1. Attuning to Asthma in Time and Place2. Three Modes of Control as Asthma Care3. Counting on Breath: Making Time with Respiratory Retraining4. The Datafication of Care5. Public Health Carescapes for Climate ChangeConclusionAcknowledgmentsNotesBibliographyIndex
£81.00
