Respiratory medicine Books

284 products


  • Pilbeams Mechanical Ventilation

    Elsevier - Health Sciences Division Pilbeams Mechanical Ventilation

    Book SynopsisTable of ContentsChapter 1 Basic Terms and Concepts of Mechanical Ventilation Chapter 2 How Ventilators Work Chapter 3 How a Breath Is Delivered Chapter 4 Establishing the Need for Mechanical Ventilation Chapter 5 Selecting the Ventilator and the Mode Chapter 6 Initial Ventilator Settings Chapter 7 Final Considerations in Ventilator Setup Chapter 8 Initial Patient Assessment Chapter 9 Ventilator Graphics Chapter 10 Assessment of Respiratory Function Chapter 11 Hemodynamic Monitoring Chapter 12 Methods to Improve Ventilation in Patient-Ventilator Management Chapter 13 Improving Oxygenation and Management of Acute Respiratory Distress Syndrome Chapter 14 Ventilator-Associated Pneumonia Chapter 15 Sedatives, Analgesics, and Paralytics Chapter 16 Extrapulmonary Effects of Mechanical Ventilation Chapter 17 Effects of Positive Pressure Ventilation on the Pulmonary System Chapter 18 Troubleshooting and Problem Solving Chapter 19 Basic Concepts of Noninvasive Positive Pressure Ventilation Chapter 20 Weaning From and Discontinuation of Mechanical Ventilation Chapter 21 Long-Term Ventilation Chapter 22 Neonatal and Pediatric Mechanical Ventilation Chapter 23 Special Techniques Used in Ventilatory Support Appendix A Answer Key Appendix B Review of Abnormal Physiological Processes Appendix C Graphics Exercises Glossary Index

    £101.59

  • Body By Breath: The Science and Practice of

    Victory Belt Publishing Body By Breath: The Science and Practice of

    3 in stock

    Book Synopsis

    3 in stock

    £52.79

  • Respiratory System

    Clinical Press Ltd Respiratory System

    Book SynopsisMost postgraduate examinations now include radiographic interpretation. This may be presented as a slide show of as a film-viewing session. Radiographs and other imaging modalities are also used ubiquitously in the viva' section of most such examinations including those of the American Boards and professional societies and universities worldwide. This series of Clinical Film Viewing will assist candidates to prepare for this process. Each book examines a particular system or technique followed by profusely illustrated cases typical of those presented in postgraduate examinations.

    £14.25

  • Workbook for Raus Respiratory Care Pharmacology

    Elsevier - Health Sciences Division Workbook for Raus Respiratory Care Pharmacology

    15 in stock

    Book SynopsisTable of ContentsUnit I: Basic Concepts and Principles in Pharmacology 1. Introduction to Respiratory Care Pharmacology 2. Principles of Drug Action 3. Administration of Aerosolized Agents 4. Calculating Drug Doses 5. The Central and Peripheral Nervous Systems Unit II: Drugs Used to Treat the Respiratory System 6. Adrenergic (Sympathomimetic) Bronchodilators 7. Anticholinergic (Parasympatholytic) Bronchodilators 8. Xanthines 9. Mucus-Controlling Drug Therapy 10. Surfactant Agents 11. Corticosteroids in Respiratory Care 12. Nonsteroidal Antiasthma Agents 13. Aerosolized Antiinfective Agents 14. Antimicrobial Agents 15. Cold and Cough Agents 16. Selected Agents of Pulmonary Value 17. Neonatal and Pediatric Aerosolized Drug Therapy Unit III: Critical Care, Cardiovascular, and Polysomnography Agents 18. Skeletal Muscle Relaxants (Neuromuscular Blocking Agents) 19. Diuretic Agents 20. Drugs Affecting the Central Nervous System 21. Vasopressors, Inotropes, and Antiarrhythmic Agents 22. Drugs Affecting Circulation: Antihypertensives, Antianginals, Antithrombotics 23 Sleep and Sleep Pharmacology

    15 in stock

    £35.14

  • Ruppels Manual of Pulmonary Function Testing

    Elsevier - Health Sciences Division Ruppels Manual of Pulmonary Function Testing

    Book SynopsisTable of ContentsChapter 1 Indications for Pulmonary Function Testing Chapter 2 Spirometry Chapter 3 Diffusing Capacity Tests Chapter 4 Lung Volumes, Airway Resistance and Gas Distribution Tests Chapter 5 Ventilation and Ventilatory Control Test Chapter 6 Blood Gases and Related Tests Chapter 7 Cardiopulmonary Exercise Testing and Field Tests Chapter 8 Pediatric Pulmonary Function Testing Chapter 9 Bronchoprovocation Challenge Testing Chapter 10 Specialized Test Regimens Chapter 11 Pulmonary Function Testing Equipment Chapter 12 Quality Systems in the Pulmonary Function Laboratory Chapter 13 Reference Values and Interpretation Strategies Appendix A Answers to Self -Assessment Questions Glossary Index

    £63.89

  • Pediatric Respiratory Diseases: A Comprehensive

    Springer Nature Switzerland AG Pediatric Respiratory Diseases: A Comprehensive

    1 in stock

    Book SynopsisThis is a comprehensive and authoritative textbook on pediatric pulmonology. Edited by Pablo Bertrand and Ignacio Sánchez, renowned academics and pediatricians from the Pontifical Catholic University of Chile, it encompasses five sections and 74 chapters, presenting and discussing the most important topics related to pediatric respiratory diseases. Written and presented in a simple and didactic format, it intends to ease learning and settlement of doubts in pediatric respiratory diseases. The reader is naturally introduced into the physiology, diagnosis, syndromes, diseases and the treatment associated with the respiratory pathologies affecting children. The chapters include algorithms for the treatment of various syndromes and updated treatment proposals grounded in evidence-based medicine for more than 50 pulmonary diseases. Pediatric Respiratory Diseases – A Comprehensive Textbook is an essential reference for the proper clinical approach to respiratory diseases in children. It is intended for all interns, residents and fellows with interest in pediatric pulmonary medicine, as well as practicing physicians, general practitioners, pediatricians and pulmonologists who face pediatric respiratory disorders in daily clinical practice.Table of ContentsTABLE OF CONTENTS.-CHAPTER 1: History of Training Specialists in Respiratory Diseases.-CHAPTER 2: Development of the Respiratory System.-CHAPTER 3: Physiological basis of the respiratory system.-CHAPTER 4: Clinical History and Physical Examination of the Respiratory System.-CHAPTER 5: Physiological Evolution of Sleep.-CHAPTER 6: Immunological Defense Mechanisms of the Respiratory System.-CHAPTER 7: New Frontiers in Research on the Respiratory System.-CHAPTER 8: Evaluating Pulmonary Function in Infants and Pre-School Children.-CHAPTER 9: Assessing Pulmonary Function in School-age Children and Adolescents.-CHAPTER 10: Assessing Respiratory Muscular Function in Patients with Neuromuscular Diseases.-CHAPTER 12: Assessing Arterial Oxygen Saturation.-CHAPTER 13: Assessing the Sleep of Newborns to Adolescents.-CHAPTER 14: Study of Infection Agents in Respiratory Diseases.-CHAPTER 15: Assessing the Airway with Flexible Endoscopy.-CHAPTER 16: Assessing the Airway with Rigid Endoscopy.-CHAPTER 17: Children with Respiratory Failure.-CHAPTER 18: Children with Persistent Cough.-CHAPTER 19: Infants with Persistent Tachypnea.-CHAPTER 20: Children with Persistent Stridor.-CHAPTER 21: Children with snoring.-CHAPTER 22: Children with Recurring Wheezing.-CHAPTER 23: Haemoptysis in Children.-CHAPTER 24: Infant with an Apparently Life Threating Event.-CHAPTER 25: Management of an Immunosuppressed Child with Lung Infection.-CHAPTER 26: Respiratory complications in Children with Neurological Diseases.-CHAPTER 27: Managing a Foreign Body in a Child’s Airway.-CHAPTER 28: Epidemiology of respiratory infections.-CHAPTER 29: Acute Laryngitis (CROUP).-CHAPTER 30: Acute Bronchiolitis.-CHAPTER 31: Community Acquired Pneumonia.-CHAPTER 32: Atypical Pneumonia.-CHAPTER 33: Complicated Pneumonia.-CHAPTER 34: Pneumonia Caused by Emerging Viral Agents.-CHAPTER 35: Pulmonary Tuberculosis.-CHAPTER 36: Respiratory Diseases in the Newborn.-CHAPTER 37: Bronchopulmonary Dysplasia.-CHAPTER 38: Allergic diseases, from the infant to the adolescent.-CHAPTER 39: Latin America Asthma Epidemiology and Related Risk Factors.-CHAPTER 40: Evaluation of Asthma Risk in Infants and Preschoolers.-CHAPTER 41: Asthma: Clinical and Diagnosis Approach.-CHAPTER 42: Asthma: Treatment.-CHAPTER 43: Primary Ciliary Dyskinesia.-CHAPTER 44: Cystic Fibrosis: Clinical and Diagnosis Approach.-CHAPTER 45: Cystic Fibrosis: Treatment.-CHAPTER 46: Pulmonary Aspergillosis.-CHAPTER 47: Post Infectious Bronchiolitis Obliterans.-CHAPTER 48: Obstructive Sleep Apnea Syndrome in Children.-CHAPTER 49: Sudden Infant Death Syndrome.-CHAPTER 50: Primary Immunodeficiencies and Immune Diseases.-CHAPTER 51: Acquired Immune Deficiency Syndrome.-CHAPTER 52: Sickle Cell Disease.-CHAPTER 53: Congenital Malformations of the Airway.-CHAPTER 54: Congenital Lung Malformations.-CHAPTER 55: Gastroesophageal Reflux and Respiratory Diseases.-CHAPTER 56: Pneumothorax and Thoracic Trauma.-CHAPTER 57: Nutrition in Chronic Respiratory Disease.-CHAPTER 58: Diseases Caused by Pollutants and Tobacco Exposure.-CHAPTER 59: Nursing care Education in Chronic Respiratory.-CHAPTER 60: Evidence-Based Medicine for Respiratory Diseases.-CHAPTER 61: Inhalation Therapy.-CHAPTER 62: Pulmonary Anti-Inflammatory Effects of Macrolides.-CHAPTER 63: Chest Physiotherapy.-CHAPTER 64: Pulmonary Rehabilitation in Children with Chronic Respiratory Diseases.-CHAPTER 65: Prolonged Hospitalization due to Chronic Respiratory Diseases.-CHAPTER 66: Oxygen Therapy.-CHAPTER 67: Acute mechanical ventilation.-CHAPTER 68: Chronic Invasive Ventilation.-CHAPTER 69: Long-Term Non-Invasive Ventilation.-CHAPTER 70: Tracheotomy.-CHAPTER 71: Airway Surgery and Endoscopic Procedures.-CHAPTER 72: Lung, Chest Cavity, and Dorsal Spine Surgery.-CHAPTER 73: Extracorporeal Circulation Membrane Oxygenation Therapy for Acute Respiratory Diseases.-CHAPTER 74: Pediatric Lung Transplantation

    1 in stock

    £132.99

  • Springer Selective Antibiotic Use in Respiratory Illness: a Family Practice Guide

    15 in stock

    Book SynopsisThe purpose of this book is to clarify the use of antibiotics in the management of the eommon respiratory illnesses seen in general practiee. The underlying philosophy, whieh embraees the avoidanee of unneeessary use, is that proper use entails a full understanding of the nature of the illness. The eoneept of seleetive antibiotie use reeognizes that respiratory illnesses eommonly eomprise multiple illness features, and that some of these features have a viral cause and some a bacterial one. In assessing antibiotic need, eaeh feature or eomponent part of an illness may be evaluated individually, so enabling adecision for antibiotie use in the illness as a whole. The nature of eaeh individual illness feature with its antibiotic indication is diseussed in sueeessive ehapters, and this aecumulated knowledge is of value in managing the more eomplex PUO and flu-like illnesses whieh are diseussed at the end of the book. The first two ehapters eneompass the principles of antibiotic use and the relationship between antibiotie preseribing and various states of the patient, e.g. allergy, pregnaney ete. An attempt has been made to justify every reeommendation or decision, and non-antibiotic management is diseussed where relevant.Table of Contents1 Antibiotics and the Patient.- Allergy.- Antibiotic Diarrhoea.- The Contraceptive Pill.- Pregnancy.- Lactation.- Neonates.- Children.- The Elderly.- Hepatic and Renal Impairment.- Drug Interactions.- Absorption.- 2 Management Principles.- 3 Pyrexia.- Febrile Convulsions.- Delirium.- Rigors.- Symptomatic Management of Pyrexia.- Antibiotic Use.- 4 Sore Throat, Tonsillitis and Pharyngitis.- Definition.- The Non-inflamed Sore Throat.- The Inflamed Throat.- Referral for Tonsillectomy.- 5 Otitis Media.- Use of the Auroscope.- Clinical Features of Acute Otitis Media.- Bacteria in Acute Otitis Media.- Secretory Otitis Media.- Management and Antibiotic Use.- Chronic Otitis Media.- 6 Sinusitis.- Clinical Features.- Bacteriology.- Management and Antibiotic Use.- 7 Laryngitis.- Croup.- Hoarseness or Loss of Voice.- 8 Coughs and Colds.- The Acute Cough.- Cold in the Nose.- Persistent Cough in Children.- Persistent Cough in Adults.- The Absent Cough.- 9 Wheezy Bronchitis in Children.- The Nature of Wheezy Bronchitis.- Recognition of Asthma.- Management of the Acute Episode.- Longerterm Management.- Differential Diagnosis.- 10 Pneumonia.- Clinical Diagnosis.- Investigation.- Infective Causes.- Management and Antibiotic Use.- Differential Diagnosis.- 11 Bronchitis, Bronchiolitis and Bronchiectasis.- Acute Bronchitis.- Acute Bronchiolitis.- Chronic Bronchitis.- Bronchiectasis.- 12 Vomiting and Diarrhoea.- Non-specific Vomiting.- Gastro-enteritis.- Management.- 13 PUO in Children.- Definition.- Emergent Diagnoses.- Management and Antibiotic Use.- 14 Influenza and the ’Flu-like Illness.- The Influenzal Illness.- Viral Causes.- Differential Diagnosis.- Clinical Assessment of the Patient with ’Flu.- Management and Antibiotic Use.

    15 in stock

    £72.68

  • Cystic Fibrosis

    Cambridge University Press Cystic Fibrosis

    1 in stock

    Book SynopsisAn informative and enjoyable book introducing the condition Cystic Fibrosis to children and their families, providing comfort, hope, and key information. Featuring easy to understand language, helpful facts and fun color illustrations, this book is part of the innovative series The Strength of My Scars by surgeon, Maria Baimas-George.Table of ContentsCystic Fibrosis – Wacky Juice Machines.

    1 in stock

    £11.99

  • Cambridge University Press Fetal and Neonatal Lung Development

    10 in stock

    Book SynopsisThis book provides an authoritative review of fetal and neonatal lung development, and is designed to provide diverse groups of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease.Trade Review'This is an outstanding work on the subspecialty of fetal and neonatal pulmonology.' Nano Khilnani, Biz India Online News (www.bizindia.net)Table of ContentsList of contributors; Preface; 1. The genetic programs regulating embryonic lung development and induced pluripotent stem cell differentiation Finn Hawkins, Scott A Rankin, Darrell N. Kotton and Aaron M. Zorn; 2. Early development of the mammalian lung-branching morphogenesis Kathleen M. Stewart and Edward E. Morrisey; 3. Pulmonary vascular development Timothy D. Le Cras and Marlene Rabinovitch; 4. Transcriptional mechanisms regulating pulmonary epithelial maturation: a systems biology approach Jeffrey A. Whitsett and Yan Xu; 5. Environmental effects on lung morphogenesis and function: tobacco products, combustion products and other sources of pollution Cindy T. McEvoy and Eliot R. Spindel; 6. Congenital malformations of the lung Susan E. Wert and Kathryn A. Wikenheiser-Brokamp; 7. Lung structure at preterm and term birth Jason C. Woods and Johannes C. Schittny; 8. Surfactant during lung development Timothy E. Weaver, Lawrence M. Nogee and Alan Jobe; 9. Initiation of breathing at birth Arjan te Pas and Stuart Hooper; 10. Perinatal modifiers of lung structure and function Suhas G. Kallapur and Sailesh Kotecha; 11. Chronic neonatal lung injury and care strategies to decrease injury Robert P. Jankov and A. Keith Tanswel; 12. Apnea and control of breathing Christopher C. Stryker, Andrew Dylag and Richard J. Martin; 13 Alveolarization into adulthood Manjith Narayanan; 14. Physiologic assessment of lung growth and development throughout infancy and childhood Anne-Marie Gibson, Sarath Ranganathan and Lex W. Doyle; 15. Perinatal disruptions of lung development: mechanisms and implications for chronic lung diseases Michael A. O'Reilly; 16. Lung growth through the 'life course' and predictors and determinants of chronic respiratory disorders Fernando D. Martinez; 17. The lung structure maintenance program: sustaining lung structure during adulthood and implications for COPD risk Norbert F. Voelkel and Masahiro Sakagami; Index.

    10 in stock

    £136.80

  • Respiratory Disease in Pregnancy

    Cambridge University Press Respiratory Disease in Pregnancy

    7 in stock

    Book SynopsisRespiratory diseases affect a large proportion of the population and can cause complications when associated with pregnancy. Pregnancy induces profound anatomical and functional physiological changes in the mother, and subjects the mother to pregnancy-specific respiratory conditions. Reviewing respiratory conditions both specific and non-specific to pregnancy, the book also addresses related issues such as smoking and mechanical ventilation. Basic concepts for the obstetrician are covered, including patient history, physiology and initial examinations. Topics such as physiological changes during pregnancy and placental gas exchange are discussed for the non-obstetrician. Guidance is practical, covering antenatal and post-partum care, as well as management in the delivery suite. An essential guide to respiratory diseases in pregnancy, this book is indispensable to both obstetricians and non-obstetric physicians managing pregnant patients.Trade Review'Overall, the book is quite timely given the current COVID-19 pandemic … The book is well written and easy to read. It provides excellent foundational knowledge … For the obstetrician, it is a great resource to facilitate more educated exchanges with consultants. For non-obstetricians consulted on obstetric patients, it provides a nice review of how pregnant women are different from non-pregnant adults. There are not many books dedicated to just the respiratory system, which makes it more valuable to healthcare providers looking for this specific type of information.' Vanessa Laibl Rogers, Doody's Book Review ServiceTable of ContentsList of contributors; Section 1. The Basics – for the Obstetrician: 1. Respiratory physiology and terminology Timothy Crozier; 2. Pulmonary assessment in pregnancy Tabassum Firoz; 3. Approach to common respiratory problems in pregnancy Karen Patterson; Section 2. The Basics – for the Non-Obstetrician: 4. Cardiopulmonary physiological alterations in pregnancy Niamh Hayes and Thomas Drew; 5. Gas exchange across the placenta Brahmdeep S. Saini, Janna L. Morrison and Mike Seed; Section 3. Pulmonary Conditions Not Specific to Pregnancy: 6. Pulmonary infections in pregnancy Priya Daniel, Timothy Hills and Wei Shen Lim; 7. Asthma in pregnancy Danish Ahmad and Erika Yoo; 8. Cystic fibrosis in pregnancy Melanie Chin and D. Elizabeth Tullis; 9. Restrictive lung disease in pregnancy Stephen Lapinsky; 10. Pulmonary thromboembolic disease in pregnancy Wee-Shian Chan; 11. Pulmonary hypertension in pregnancy Liesbeth ten Klooster, Vicki J. Wilson, Ruth Newton, Karen Selby, Suarabh V Gandhi and David G Kiely; 12. Sickle chest syndromes in pregnancy Ann Kinga Malinowski and Nadine Shehata; 13. Sleep-disordered breathing in pregnancy Jennifer E. Dominguez and Ghada Bourjeily; 14. Acute respiratory distress syndrome and respiratory failure in pregnancy Justin Seashore and Alexander Duarte; 15. Other pulmonary conditions in pregnancy Muhammed Ehtisham, Humnah Khudayar and Patricia Russo-Magno; Section 4. Pulmonary Conditions Related to Pregnancy: 16. Dyspnea of pregnancy Stephen Lapinsky and Ghada Bourjeily; 17. Amniotic fluid embolism syndrome Marie Baldisseri; 18. Pregnancy-associated pulmonary edema Lisa Moore; Section 5. Other Pulmonary Issues in Pregnancy: 19. Smoking in pregnancy Catherine Chamberlain; 20. Radiological imaging of the chest in pregnancy Shital Gandhi and Siobhan Bacon; 21. Respiratory drug therapy in pregnancy Nika Mehta; 22. Biological and immunosuppressive respiratory therapy in pregnancy Bernadette Jenner and Catherine Nelson-Piercy; 23. Oxygen therapy in pregnancy Daniela Vaquez and Gustavo A. Plotnikow; 24. Airway management in pregnancy Kyle Jespersen and Michaela K. Farber; 25. Mechanical ventilation in pregnancy José Rojas-Suarez and Jezid Miranda; Index.

    7 in stock

    £83.59

  • Bronchiolitis: Observations, Interventions &

    Nova Science Publishers Inc Bronchiolitis: Observations, Interventions &

    1 in stock

    Book SynopsisRespiratory Syncytial Virus (RSV) is a ubiquitous and highly contagious virus belonging to the Paramyxoviridae family. RSV is the most common cause of bronchiolitis and hospitalisation during the first year of life and it might be associated with an increased risk of recurrent wheeze, asthma as well as with decreased respiratory function in school-aged children. In Chapter One, the authors report the most updated evidences for the environmental prophylaxis and summarise current recommendations about targeted palivizumab immunisation and ongoing trials on RSV vaccine development. Chapter Two summarises the most recent literature regarding acute bronchiolitis to provide an evidence-based approach to the management and treatment of this disease. In Chapter Three, the authors review risk factors associated with hospitalisation and pediatric intensive care unit admission. The final chapter illustrates a practical, pathophysiological and step up approach to children affected by severe bronchiolitis.

    1 in stock

    £83.29

  • Pleural Effusions: Causes, Types and Treatment

    Nova Science Publishers Inc Pleural Effusions: Causes, Types and Treatment

    1 in stock

    Book SynopsisThere is extensive literature available on pleural effusions and in recent years there has been significant developments in their diagnostic evaluation. The use of point of care ultrasound, pleural manometry, and medical pleuroscopy has expanded over the last decade. The goal of writing this book was to become a source or reference for clinicians who manage patients with pleural effusions. Pleural space contains minimal amount of fluid and physiological processes keep a constant equilibrium so that it remains as such. Pleural effusions develop as a result of processes that disrupt this fine balance, as in heart failure, infections, and malignancies, which account for majority of the pleural effusions. Besides these three common causes, pleural effusions cause symptoms in many other conditions, some of which are common regardless of the etiology of the pleural effusion, such as, dyspnea and cough. Diagnosing the etiology becomes important as management can vary depending upon the cause. In some situations, involvement of the pleural space portends a poor prognosis, such as in malignancies and treatment focuses on symptom relief. The chapters in thise book span over a wide range of topics involving pleural effusions. Initial chapters focus on clinical presentation, radiology, diagnostic evaluation, and classification of pleural effusions. There is a chapter on malignant pleural effusions, pleural infections and empyema, rheumatological causes of pleural effusions and tubercular and fungal pleural effusions. Pleural manometry is an important tool in the work-up of a trapped lung and an entire chapter is dedicated to this topic. Another chapter focuses on interventional procedures including pleuroscopy. The last two chapters go over cases of pleural effusions which cover many of the topics covered in the book. The book compiles recent literature on pleural effusions with an aim to help clinicians manage patients with pleural effusions effectively.

    1 in stock

    £163.19

  • New Developments in Asthma Research

    Nova Science Publishers Inc New Developments in Asthma Research

    1 in stock

    Book SynopsisAsthma is a disease that affects the lungs. It causes repeated episodes of wheezing, breathlessness, chest tightness, and night-time or early morning coughing. Tens of millions of people throughout the world suffer from asthma. Airways are the paths that carry air to the lungs. As the air moves through the lungs, the airways become smaller, like branches of a tree. During an attack, the sides of the airways in the lungs become inflamed and swollen. Muscles around the airways tighten, and less air passes in and out of the lungs. Excess mucus forms in the airways, clogging them even more. The attack, also called an episode, can include coughing, chest tightness, wheezing, and trouble breathing. Environmental exposures, such as house dust mites and environmental tobacco smoke, are important triggers of an attack. This book presents important new research on the causes on asthma as well as its diagnosis and treatment.

    1 in stock

    £116.24

  • New Topics in Tuberculosis Research

    Nova Science Publishers Inc New Topics in Tuberculosis Research

    1 in stock

    Book SynopsisTuberculosis, the disease that the World Health Organization has recently declared a global emergency, was supposedly defeated by antibiotics half a century ago. It has returned in a highly contagious and fatal new form that cannot be treated with conventional drugs. Multidrug-resistant TB (MDR-TB), could cause some 10 million deaths over the next decade and is thriving in the overcrowded prisons of the former Soviet Union. The virtual collapse of the world''s borders means that refugees, tourists, immigrants, business travellers, and others can spread the TB bacillus very efficiently. London, for example, has experienced a 100% increase in reported cases in the past 10 years. This book covers all aspects of the disease: epidemiology, microbiology, diagnosis, treatment, control and prevention. Leading research is presented from centres around the world.

    1 in stock

    £176.24

  • Asthma: Etiology, Pathogenesis & Treatment

    Nova Science Publishers Inc Asthma: Etiology, Pathogenesis & Treatment

    1 in stock

    Book SynopsisAsthma is characterised by intermittent airway obstruction, bronchial smooth muscle cell hyper-reactivity to broncho-constrictors, and chronic bronchial inflammation. The aetiology of asthma is heterogeneous with a number of established risk factors. The prevalence of asthma has been increasing in all age and racial groups during the past two decades. The variation in prevalence rates for racial and ethnic groups probably results from differences in genetic, environmental, social, and cultural influences. Factors affecting increased asthma prevalence include obesity and exposure to environmental irritants. The population has become increasingly sedentary, spending more time indoors where the exposure to allergens, such as mould, dust mites, and cockroach dust, is more prevalent. In addition, the increased prevalence of allergic rhinitis and atopy related to exposure to allergens at an early age is associated with the prevalence of asthma. This book provides new research on this field from around the globe.

    1 in stock

    £113.24

  • Acute Lung Injury: Epidemiology, Health Effects

    Nova Science Publishers Inc Acute Lung Injury: Epidemiology, Health Effects

    1 in stock

    Book SynopsisIn this book, authors review the current knowledge on acute lung injury (ALI). ALI/acute respiratory distress syndrome (ARDS) is characterized by diffuse alveolar damage, alveolar capillary leakage, lung edema, neutrophil-derived inflammation, and surfactant dysfunction. These changes lead to clinical manifestations of decreased lung compliance, severe hypoxemia, and bilateral pulmonary infiltrates. In the first chapter the authors describe how two different models of multi-causality (intuitively appealing threshold model and abstract sufficient cause model), both of which are commonly used in the description of the etiology of diseases, can be applied to transfusion related acute lung injury (TRALI) and can both be used to describe the same observed relations between multiple risk factors and TRALI. In the second chapter, a dysfunction of the normal endothelialepithelial barriers and its role in the development of acute lung injury is described. Two leading pathogenic mechanisms of ALI are increased endothelial permeability and reduced alveolar liquid clearance capacity. Understanding of the fundamental mechanisms involved in the regulation of endothelial permeability is essential for the development of barrier protective therapeutic strategies. The following two chapters are focused on novel therapeutic strategies used in the treatment of ALI and more severe form acute respiratory distress syndrome (ARDS). Appropriate treatment involves protective lung ventilation, optimal fluid management, and pharmacological treatment. Despite that there are several possibilities of potentially beneficial pharmacotherapy of ALI/ARDS, the results of experimental and clinical studies are often controversial. The authors review the use of various pharmacological agents (including corticosteroids, neutrophil elastase inhibitors, anticoagulants, pulmonary vasodilators, antioxidants, methylxanthines, exogenous surfactant, gene-therapy, cell therapy, nitric oxide, myorelaxants, beta-agonists) and critically evaluate their effects in animal models and in patients with ALI/ARDS.

    1 in stock

    £67.99

  • Respiratory Diseases: Causes, Treatment and

    Nova Science Publishers Inc Respiratory Diseases: Causes, Treatment and

    1 in stock

    Book Synopsis

    1 in stock

    £106.49

  • Hypoxia: Causes, Types & Management

    Nova Science Publishers Inc Hypoxia: Causes, Types & Management

    1 in stock

    Book SynopsisLow oxygenation levels are a hallmark of numerous pathologic conditions. Hypoxia occurs in chronic diseases of brain, kidneys and liver. Malignant tumours grow rapidly with insufficient vasculature, thereby producing areas of chronic hypoxia. This book contains contributions from an international group of authors covering a wide range of situations in benign as well as malignant diseases, in which understanding the role of hypoxia may lead to novel diagnostic and therapeutic strategies. These include modulation of tissue oxygenation as well as treatment concepts directed specifically at hypoxic cells.

    1 in stock

    £206.24

  • Asthma: Causes, Complications & Treatment

    Nova Science Publishers Inc Asthma: Causes, Complications & Treatment

    1 in stock

    Book SynopsisAsthma is a complex disorder characterized by variable and recurring symptoms, airflow obstruction, bronchial hyper-responsiveness, and underlying inflammation. Although asthma is commonly thought of as a disease of children and young adults, a significant percentage of the older adult population is affected and carry a higher rate of morbidity and mortality from the disease. This book examines the causes, complications and treatment of asthma with topics including mathematical modelling in aspirin-induced asthma; the role of neuroimmune and psychological systems in the pathophysiology of bronchial asthma; special considerations of asthma in older adults; changes in the respiratory epithelium in bronchial asthma; and epidemiology of asthma during pregnancy.

    1 in stock

    £106.49

  • Fighting Lung Cancer Through the HER Family of

    Nova Science Publishers Inc Fighting Lung Cancer Through the HER Family of

    1 in stock

    Book SynopsisLung cancer is the most common and most lethal malignancy world-wide, causing 1.4 million diseases every year. Half of non-small cell lung cancers (NSCLC) are diagnosed at such an advanced stage that a cure cannot be considered a realistic aim, and over 75% of cases selected for a curative treatment eventually relapse within five years. The 5-year overall survival rates are less than 20% for NSCLC patients. As a disease, NSCLC demands our maximum abilities as researchers, physicians, and care-givers, and a continuous updating of our knowledge. Conventional chemotherapy for advanced NSCLC does not provide a great long-term benefit in terms of survival. Accordingly, a different therapeutic approach has to be explored. The human epidermal growth factor family of surface receptors (HER) became a critical target to be investigated. The epidermal growth factor receptor (EGFR) is over-expressed in over 80% of non-small cell lung cancer. The presence of sensitising conformational mutations in the EGFR increases the efficacy of modern tyrosine kinase inhibitors against its inner portion (EGFR-TKI). The EGFR-TKIs greatly prolong disease-free survival of those patients harbouring sensitising EGFR mutations, and have been suggested as an essential tool in the therapeutic repertoire. This volume aims to serve as an updated compendium of biology and applications of anti-EGFR therapies, and offers a look at the future of anti-HER therapy in lung cancer. This volume exhaustively reviews and discusses: 1) the nature and significance of activating EGFR mutations, and those clinical and pathological phenomena related to HER alterations; 2) the most common laboratory methodologies to study EGFR, and the future of HER analysis; 3) the right time to analyse EGFR mutations and evolutionary changes in the HER; 4) EGFR-TKI application in unselected and selected NSCLC patients; 5) upcoming anti-HER therapies; 6) the eventual role of anti-HER therapies in early NSCLC; 7) mechanisms of acquired resistance to anti-HER therapies, and experimental and conventional strategies to bypass them; 8) the application of anti-HER therapies in other malignancies. This book is an indispensable handbook for all those specialists devoted to the diagnosis and management of lung cancer.

    1 in stock

    £149.99

  • Fighting Lung Cancer with Conventional Therapies

    Nova Science Publishers Inc Fighting Lung Cancer with Conventional Therapies

    1 in stock

    Book SynopsisLung cancer, the most common and deadliest malignancy worldwide, is one of the biggest challenges for modern oncology. Although lung cancer presents the same incidence as breast or colorectal cancer, it causes as much deaths as breast and colorectal cancers together. Lung cancer demands our abilities as researchers, physicians, and care-givers in a multidisciplinary approach. Genetic, biology, pharmacy, pneumology, internal medicine, radiology, pathology, thoracic surgery, radiation, medical oncology and palliative care departments are essential members of the thoracic tumor boards. Fighting Lung Cancer through Conventional Therapies is the second volume of a saga entirely devoted to the treatment of lung cancer. In the age of targeted oncology, more than 90% of lung cancer patients are managed with conventional surgery, radiation, and chemotherapy only. Furthermore, 100% of them will need conventional treatments during the course of the disease. This volume updates indications, techniques, and applications of surgery, radiotherapy and chemotherapy in the treatment of lung cancer by an international team of experts. Included within these pages are: epidemiology and pathology; baseline and mediastinal staging; minimally invasive surgery, video-assisted thoracic surgery, and standard surgery in early-stage non-small cell lung cancer; radiation therapy for early non-small cell lung cancer; the management of locally advanced non-small cell cancer; applications of surgery to metastatic lung cancer; the new role of radiotherapy in metastatic non-small cell lung cancer; conventional chemotherapy as well as experimental treatments and combos with targeted therapies; the treatment of early and advanced small cell lung cancer; the role of palliative supportive care; and the integration of all those disciplines in multidisciplinary tumor boards are exhaustively reviewed.

    1 in stock

    £230.39

  • COPD & the Workplace

    Nova Science Publishers Inc COPD & the Workplace

    1 in stock

    Book SynopsisChronic obstructive pulmonary disease (COPD) is a major cause of disability and is the fourth leading cause of death throughout the world. Although cigarette smoking is the major and best studied causative factor of COPD, there is consistent evidence that a substantial proportion of COPD cases cannot be explained by smoking. Other noxious particles and gases, such as workplace dusts, vapours, fumes or gases, indoor air pollution from burning biomass fuels during cooking foods and heating spaces, and air pollution in urban areas are important risk factors of COPD. According to collected data, 15-20% of COPD cases are likely to be caused or made worse by work; around 4,000 COPD deaths every year are related to workplace exposures, and 40% of COPD patients are below the retirement age. The development of COPD as a consequence of workplace exposure is a matter of growing interest and importance. There is no doubt that certain workplace exposures enhance the risk of COPD and may do so independently of or in concordance with cigarette smoking. The evidence is most coherent for work that entails exposure to coal, silica, welding fumes, cadmium fumes, cotton dust, farming dusts, grain dust and/or wood dust. The research found consistent associations between workplace exposures and COPD across a wide range of sectors, describing a nearly uniform pattern of exposure-response relationships. Based on the research, affected occupations include miners, construction workers, road workers, tunnel workers, welders, glass workers, metal workers, foundry workers, textile workers, farm laborers, wood workers, chemical workers, and rubber workers; in other words, a working population including millions and millions workers worldwide have been affected. It seems that occupational risk for COPD, although variable, is smaller compared with that of cigarette smoking. However, it affects a large proportion of the population and its contribution to the total burden of COPD cannot not be neglected. In addition, existing evidence indicates that workplace exposure may influence the course of COPD as factors with significant impacts on the progression and severity of the disease. As in the case of the workplace agents being causative factors of COPD, the mechanisms underlying this effect still are not fully understood. This monograph contains seven chapters which cover the most important aspects of this issue. It summarizes results of the studies performed in this area of research and conclusions based on them. This monograph also presents the author''s view regarding the influence of workplace exposures on the development and progression of COPD. In addition, it may be a basis for further research for better understanding of the association between COPD and workplace exposures.

    1 in stock

    £83.29

  • Cystic & Idiopathic Pulmonary Fibrosis: Risk

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