Physiology Books

1386 products


  • Cambridge University Press A History of Nerve Functions

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £85.49

  • Cambridge University Press Endocrine Pharmacology

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £50.95

  • Cambridge University Press The Stress of Hot Environments

    15 in stock

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    15 in stock

    £40.84

  • Cambridge University Press Lively Membranes

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £32.29

  • Cambridge University Press Hormones and Human Behaviour 2 The Scientific Basis of Psychiatry Series Number 2

    15 in stock

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    15 in stock

    £28.99

  • Cambridge University Press Physiology of Mammals and Other Vertebrates

    15 in stock

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    15 in stock

    £39.89

  • Cambridge University Press Brain Control of Responses to Trauma

    15 in stock

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    15 in stock

    £56.04

  • 15 in stock

    £109.80

  • Cambridge University Press Muscular Contraction

    15 in stock

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    15 in stock

    £73.14

  • Cambridge University Press Brain Control of Responses to Trauma

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £134.90

  • Cambridge University Press Contribution of Nutrition to Human and Animal Health

    15 in stock

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    15 in stock

    £158.65

  • 15 in stock

    £99.75

  • Cambridge University Press Neurobiological Effects of Sex Steroid Hormones

    15 in stock

    Neurobiological Effects of Sex Steroid Hormones | BookCurl

    15 in stock

    £114.95

  • Cambridge University Press Movement Control

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £34.19

  • Cambridge University Press Body Composition Techniques in Health and Disease 36 Society for the Study of Human Biology Symposium Series Series Number 36

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £119.70

  • Cambridge University Press Vertebrate Ecophysiology

    15 in stock

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    15 in stock

    £55.09

  • Cambridge University Press Clinical Physiology

    15 in stock

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    15 in stock

    £65.54

  • Cambridge University Press Medical Physiology

    15 in stock

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    15 in stock

    £26.99

  • Cambridge University Press A Practical Guide to Vertebrate Mechanics

    15 in stock

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    15 in stock

    £114.30

  • Cambridge University Press A Practical Guide to Vertebrate Mechanics

    15 in stock

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    15 in stock

    £66.49

  • Cambridge University Press Applied Surgical Physiology Vivas

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £54.14

  • Cambridge University Press Physiology by Numbers An Encouragement to Quantitative Thinking

    15 in stock

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    15 in stock

    £52.24

  • Cambridge University Press An Introduction to Vascular Biology

    15 in stock

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    15 in stock

    £82.64

  • Cambridge University Press An Introduction to Neuroendocrinology

    15 in stock

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    15 in stock

    £158.65

  • Cambridge University Press Biological Membranes Theory of Transport Potentials and Electric Impulses

    15 in stock

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    15 in stock

    £126.35

  • Cambridge University Press Allostasis Homeostasis and the Costs of Physiological Adaptation

    15 in stock

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    15 in stock

    £118.75

  • Cambridge University Press Introduction to the Senses

    15 in stock

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    15 in stock

    £41.79

  • Cambridge University Press Hardwired Behavior What Neuroscience Reveals about Morality

    15 in stock

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    15 in stock

    £26.99

  • Cambridge University Press Allostasis Homeostasis and the Costs of Physiological Adaptation

    15 in stock

    Book SynopsisThe concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical sTrade ReviewReview of the hardback: 'This book … is very welcome as it goes a good way towards introducing readers of all levels to the concept … it is well balanced … this book will be an important text for those who want to know more.' BiologistTable of Contents1. Principles of allostasis: optimal design, predictive regulation, pathophysiology and rational therapeutics Peter Sterling; 2. Protection and damaging effects of the mediators of stress and adaptation: allostasis and allostatic load Bruce S. McEwen; 3. Merging of the homeostatic theory with the concept of allostatic load David S. Goldstein; 4. Operationalizing allostatic load Burton Singer, Carol D. Ryff and Teresa Seeman; 5. Drug addiction and allostasis George F. Koob and Michael LeMoal; 6. Adaptive fear and the pathology of anxiety and depression: an allostatic framework Jeffrey B. Rosen and Jay Schulkin; 7. A chronobiological perspective on allostasis and its application to shift work Ziad Boulos and Alan M. Rosenwasser; 8. Allostatic load and life cycles: implications for neuroendocrine control mechanisms John C. Wingfield; 9. Commentary: viability as opposed to stability: an evolutionary perspective on physiological regulation Michael L. Power.

    15 in stock

    £48.44

  • Cambridge University Press Zoonomia Volume 1

    15 in stock

    Book SynopsisThe two-volume Zoonomia (1794–6) attempts to 'reduce the facts belonging to animal life into classes, orders, genera, and species; and by comparing them with each other, to unravel the theory of diseases' and marks a new stage in the development of the science of medicine.Table of ContentsPreface; 1. Of motion; 2. Explanations and definitions; 3. The motions of the retina demonstrated by experiments; 4. Laws of animal causation; 5. Of the four faculties of motions of the sensorium; 6. Of the four classes of fibrous motions; 7. Of irritative motions; 8. Of sensitive motions; 9. Of voluntary motions; 10. Of associate motions; 11. Additional observations on the sensorial powers; 12. Of stimulus, sensorial exertion, and fibrous contraction; 13. Of vegetable animation; 14. Of the production of ideas; 15. Of the classes of ideas; 16. Of instinct; 17. The catenation of animal motions; 18. Of sleep; 19. Of reverie; 20. Of vertigo; 21. Of drunkenness; 22. Of propensity to motion; 23. Of the circulatory system; 24. Of the secretion of saliva, and of tears; 25. Of the stomach and intestines; 26. Of the capillary glands, and of the membranes; 27. Of hæmorrhages; 28. The paralysis of the lacteals; 29. The retrograde motion of the absorbent vessels; 30. The paralysis of the liver; 31. Of temperaments; 32. Diseases of irritation; 33. Of sensation; 34. Of volition; 35. Of association; 36. The periods of diseases; 37. Of digestion, secretion, nutrition; 38. Of the oxygenation of the blood in the lungs and placenta; 39. Of generation; 40. Of ocular spectra.

    15 in stock

    £53.19

  • McGraw-Hill Education High School Laboratory Manual for Human Anatomy

    7 in stock

    Book Synopsis

    7 in stock

    £34.20

  • Earthly Materials

    HarperCollins Earthly Materials

    3 in stock

    3 in stock

    £23.19

  • McGraw-Hill Education - Europe Loose Leaf Version of Regional Human Anatomy A

    Book Synopsis

    £111.42

  • Circuits Signals and Systems for Bioengineers

    Elsevier Science Publishing Co Inc Circuits Signals and Systems for Bioengineers

    4 in stock

    Book SynopsisTable of ContentsPart I - SIGNALS 1. The Big Picture: Bioengineering Signals and Systems 2. Signal Analysis in the Time Domain 3. Signal Analysis in the Frequency Domain: The Fourier Series and the Fourier Transformation 4. Signal Analysis in the Frequency Domain - Implications and Applications Part II - SYSTEMS 5. Linear Systems Analysis in the Time Domain - Convolution 6. Linear Systems Analysis in the Frequency Domain: The Transfer Function 7. Linear Systems in the Complex Frequency Domain: The Laplace Transform 8. Analysis of Discrete Linear Systems - The z-Transform and Applications to Filters 9. System Simulation and Simulink 10. Stochastic, Nonstationary, and Nonlinear Systems and Signals 11. Two-Dimensional Signals - Basic Image Analysis PART III - CIRCUITS 12. Circuits Elements and Circuit Variables 13. Analysis of Analog Circuits and Models 14. Circuit Reduction - Simplifications 15. Basic Analog Electronics - Operational Amplifiers APPENDICES Appendix A - Derivations; Appendix B - Laplace Transforms and Properties of the Fourier; Appendix C - Trigonometric and Other Formulae; Appendix D - Conversion Factors: Units; Appendix E - Complex Arithmetic; Appendix F - LF356 Specifications; Appendix G - Determinants and Cramer's Rule

    4 in stock

    £90.00

  • Anatomy  Physiology for Emergency Care

    Pearson Education (US) Anatomy Physiology for Emergency Care

    2 in stock

    Book SynopsisTable of Contents Preface 1 An Introduction to Anatomy and Physiology 2 The Chemical Level of Organization 3 Cell Structure and Function 4 The Tissue Level of Organization 5 The Integumentary System 6 The Skeletal System 7 The Muscular System 8 The Nervous System 9 The General and Special Senses 10 The Endocrine System 11 The Cardiovascular System: Blood 12 The Cardiovascular System: The Heart 13 The Cardiovascular System: Blood Vessels and Circulation 14 The Lymphatic System and Immunity 15 The Respiratory System 16 The Digestive System 17 Nutrition and Metabolism 18 The Urinary System 19 The Reproductive System 20 Development and Inheritance Appendix I Answers to Concept Check and Chapter Review Questions Appendix II A Periodic Chart of the Elements Appendix III Weights and Measures Appendix IV Normal Physiological Values Appendix V Key Notes Glossary/Index

    2 in stock

    £128.39

  • Animal Physiology

    Oxford University Press Inc Animal Physiology

    10 in stock

    Book SynopsisComprehensive, contemporary, and engaging, Animal Physiology provides evolutionary and ecological context to help students make connections across all levels of physiological scale.Table of ContentsPreface Part I Fundamentals of PhysiologyChapter 1 Animals and Environments: Function on the Ecological StageChapter 2 Molecules and Cells in Animal PhysiologyChapter 3 Genomics, Proteomics, and Related Approaches to PhysiologyChapter 4 Physiological Development and EpigeneticsChapter 5 Transport of Solutes and WaterPart II Food, Energy, and TemperatureChapter 6 Nutrition, Feeding, and DigestionChapter 7 Energy MetabolismChapter 8 Aerobic and Anaerobic Forms of MetabolismChapter 9 The Energetics of Aerobic ActivityChapter 10 Thermal RelationsChapter 11 Food, Energy, and Temperature AT WORK: The Lives of Mammals in Frigid PlacesPart III Integrating SystemsChapter 12 NeuronsChapter 13 SynapsesChapter 14 Sensory ProcessesChapter 15 Nervous System Organization and Biological ClocksChapter 16 Endocrine and Neuroendocrine PhysiologyChapter 17 ReproductionChapter 18 Integrating Systems AT WORK: Animal NavigationPart IV Movement and MuscleChapter 19 Control of MovementChapter 20 MuscleChapter 21 Movement and Muscle AT WORK: Plasticity in Response to Use and DisusePart V Oxygen, Carbon Dioxide, and Internal TransportChapter 22 Introduction to Oxygen and Carbon Dioxide in PhysiologyChapter 23 External Respiration: The Physiology of BreathingChapter 24 Transport of Oxygen and Carbon Dioxide in Body Fluids (with an Introduction to Acid- Base Physiology)Chapter 25 CirculationChapter 26 Oxygen, Carbon Dioxide, and Internal Transport AT WORK: Diving by Marine MammalsPart VI Water, Salts, and ExcretionChapter 27 Water and Salt Physiology: Introduction and MechanismsChapter 28 Water and Salt Physiology of Animals in Their EnvironmentsChapter 29 Kidneys and Excretion (with Notes on Nitrogen Excretion)Chapter 30 Water, Salts, and Excretion AT WORK: Mammals of Deserts and Dry SavannasAppendixGlossary Index

    10 in stock

    £201.40

  • 3 in stock

    £56.05

  • Self Comes to Mind

    Knopf Doubleday Publishing Group Self Comes to Mind

    10 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    10 in stock

    £15.30

  • Blood and Guts

    Little, Brown & Company Blood and Guts

    Book SynopsisDiscusses the elements of the human body. Includes suggestions for related experiments and projects.

    £14.99

  • Nursing Key Topics Review Pathophysiology

    Elsevier - Health Sciences Division Nursing Key Topics Review Pathophysiology

    15 in stock

    Book Synopsis

    15 in stock

    £36.57

  • Cengage Learning Anatomy Physiology LooseLeaf Version

    2 in stock

    2 in stock

    £198.99

  • The Body

    Random House USA Inc The Body

    10 in stock

    Book Synopsis

    10 in stock

    £28.00

  • Anatomy and Physiology for the Manual Therapies

    John Wiley & Sons Inc Anatomy and Physiology for the Manual Therapies

    2 in stock

    Book SynopsisAnyone planning on a career in the therapeutic sciences requires a unique foundation in the basic sciences of the human body. This new book offers detailed content on the muscles, skeleton, and nervous system, but also provides the necessary information on other systems.Table of Contents1.ORGANIZATION OF THE HUMAN BODY 1 1.1 Anatomy and Physiolo Defined 2 1.2 Levels of Organization and Body Systems 2 1.3 Life Processes 6 1.4 Homeostasis: Maintain Limits 8 1.5 Aging and Homeostasis 12 1.6 Anatomical Terms 12 1.7 Body Cavities 17 1.8 Medical Imaging 20 2 INTRODUCTORY CHEMISTRY 28 2.1 Introduction to Chemistry 29 2.2 Chemical Compounds and Life Processes 35 3 CELLS 47 3.1 A Generalized View of the Cell 48 3.2 Plasma Membrane 49 3.3 Transport Across the Plasma Membrane 50 3.4 Cytoplasm 57 3.5 Nucleus 63 3.6 Gene Action: Protein Synthesis 64 3.7 Somatic Cell Division 68 3.8 Cancer 70 3.9 Aging and Cells 72 4 TISSUES 77 4.1 Types of Tissues 78 4.2 Cell Junctions 78 4.3 Epithelial Tissue 79 4.4 Connective Tissue 89 4.5 Membranes 101 4.6 Musular Tissue 102 4.7 Nervous Tissue 104 4.8 Tissue Repair: Restoring Homeostasis 105 4.9 Aging and Tissues 106 5 THE INTEGUMENTARY SYSTEM 111 5.1 Structure of the Skin 112 5.2 Accessory Structures of the Skin 118 5.3 Types of Skin 123 5.4 Functions of the Skin 124 5.5 Maintaining Homeostasis: Skin Wound Healing 125 5.6 Skin Conditions Important to Therapists 127 5.7 Aging and the Integumentary System 130 6.BONE TISSUE 135 6.1 Functions of Bone and the Skeletal System 136 6.2 Structure of Bone 136 6.3 Histology of Bone Tissue 138 6.4 Blood and Nerve Supply of Bone 141 6.5 Bone Formation 142 6.6 Bone Growth 145 6.7 Bones and Homeostasis 147 6.8 Aging and Bone Tissue 152 7 THE SKELETAL SYSTEM:THE AXIAL SKELETON 159 7.1 Divisions of the Skeletal System 160 7.2 Types of Bones 160 7.3 Bone Surface Markings 162 7.4 Skull 162 7.5 Hyoid Bone 177 7.6 Vertebral Column 177 7.7 Thorax 186 7.8 Disorders of the Axial Skeleton 189 8 THE SKELETAL SYSTEM:THE APPENDICULAR SKELETON 195 8.1 Pectoral (Shoulder) Girdle 196 8.2 Upper Limb (Extremity) 199 8.3 Pelvic (Hip) Girdle 205 8.4 Comparison of Female and Male Pelves 209 8.5 Comparison of Pectoral and Pelvic Girdles 210 8.6 Lower Limb (Extremity) 211 9 JOINTS 221 9.1 Joint Classifications 222 9.2 Fibrous Joints 222 9.3 Cartilaginous Joints 224 9.4 Synovial Joints 225 9.5 Types of Movements at Synovial Joints 230 9.6 Selected Joints of the Body 236 9.7 Factors Affecting Contact and Range of Motion at Synovial Joints 251 9.8 Arthroplasty 252 9.9 Aging and Joints 253 10 MUSCULAR TISSUE 257 10.1 Overview of Muscular Tissue 258 10.2 Skeletal Muscle Tissue 259 10.3 Contraction and Relaxation of Skeletal Muscle Fibers 263 10.4 Metabolism of Skeletal Muscle Tissue 268 10.5 Control of Muscle Tension 270 10.6 Muscle Spasms 273 10.7 Exercise and Skeletal Muscle Tissue 277 10.8 Cardiac Muscle Tissue 277 10.9 Smooth Muscle Tissue 278 10.10 Aging and Muscular Tissue 279 11 THE MUSCULAR SYSTEM: THE MUSCLES OF THE HEAD AND NECK 284 11.1 How Skeletal Muscles Produce Movement 285 11.2 How Skeletal Muscles Are Named 289 11.3 Principal Skeletal Muscles of the Head and Neck 289 12 THE MUSCULAR SYSTEM:THE MUSCLES OF THE TORSO 316 13 THE MUSCULAR SYSTEM:THE MUSCLES OF THE UPPER LIMB 336 14 THE MUSCULAR SYSTEM: THE MUSCLES OF THE TORSO 316 14.1 Introduction to the Muscles of the Lower Limb (Extremity) 370 14.2 Muscle Interactions 398 15 NERVOUS TISSUE 403 15.1 Overview of the Nervous System 404 15.2 Histology of Nervous Tissue 407 15.3 Electrical Signals in Neurons 413 15.4 Synaptic Transmission 418 15.5 Regeneration and Repair of Nervous Tissue 421 16 THE SPINAL CORD AND SPINAL NERVES 426 16.1 Spinal Cord Anatomy 427 16.2 Spinal Nerves 430 16.3 Spinal Cord Physiology 444 16.4 Traumatic Injuries of the Spinal Cord 458 17 THE BRAIN AND CRANIAL NERVES 463 17.1 The Brain 464 17.2 Cranial Nerves 477 17.3 Aging and the Nervous System 479 18 THE AUTONOMIC NERVOUS SYSTEM 483 18.1 Introduction to the Autonomic Nervous System 484 18.2 Comparison of Somatic and Autonomic Nervous Systems 484 18.3 Structure of the Autonomic Nervous System 486 18.4 Functions of the Autonomic Nervous System 491 18.5 Integration and Control of Autonomic Functions 492 19 SOMATIC AND SPECIAL SENSES 498 19.1 Overview of Sensations 499 19.2 Somatic Senses 500 19.3 Special Senses and Olfaction: Sense of Smell 504 19.4 Gustation: Sense of Taste 506 19.5 Vision 507 19.6 Hearing and Equilibrium 515 19.7 Aging and the Special Senses 521 20 THE ENDOCRINE SYSTEM 527 20.1 Endocrine Glands 528 20.2 Hormone Action 528 20.3 Hypothalamus and Pituitary Gland 530 20.4 Thyroid Gland 535 20.5 Parathyroid Glands 538 20.6 Pancreatic Islets 539 20.7 Adrenal Glands 542 20.8 Ovaries and Testes 545 20.9 Pineal Gland 545 20.10 Other Hormones 546 20.11 The Stress Response 547 20.12 Aging and the Endocrine System 547 21 THE CARDIOVASCULAR SYSTEM: THE BLOOD 553 21.1 Functions of Blood 554 21.2 Components of Whole Blood 554 21.3 Hemostasis 563 21.4 Blood Groups and Blood Types 566 22 THE CARDIOVASCULAR SYSTEM: THE HEART 571 22.1 Structure and Organization of the Heart 572 22.2 Blood Flow and Blood Supply of the Heart 579 22.3 Conduction System of the Heart 581 22.4 Electrocardiogram 583 22.5 The Cardiac Cycle 584 22.6 Cardiac Output 586 22.7 Exercise and the Heart 590 23 THE CARDIOVASCULAR SYSTEM: BLOOD VESSELS AND CIRCULATION 594 23.1 Blood Vessel Structure and Function 595 23.2 Blood Flow Through Blood Vessels 599 23.3 Checking Circulation 603 23.4 Circulatory Routes 603 23.5 Aging and the Cardiovascular System 620 24 THE LYMPHATIC SYSTEM AND IMMUNITY 627 24.1 Overview of Immunity 628 24.2 Lymphatic System Structure and Function 628 24.3 Innate Immunity 634 24.4 Adaptive Immunity 636 24.5 Aging and the Immune System 645 25 THE RESPIRATORY SYSTEM 651 25.1 Overview of the Respiratory System 652 25.2 Organs of the Respiratory System 653 25.4 Exchange of Oxygen and Carbon Dioxide 664 25.5 Transport of Respiratory Gases 667 25.6 Control of Respiration 667 25.7 Exercise and the Respiratory System 671 25.8 Aging and the Respiratory System 671 26 THE DIGESTIVE SYSTEM 677 26.1 Overview of the Digestive System 678 26.2 Layers of the GI Tract and the Peritoneum 679 26.3 Mouth 681 26.4 Pharynx and Esophagus 683 26.5 Stomach 685 26.6 Pancreas 688 26.7 Liver and Gallbladder 688 26.8 Small Intestine 692 26.9 Large Intestine 697 26.10 Phases of Digestion 700 26.11 Aging and the Digestive System 701 27 NUTRITION AND METABOLISM 707 27.1 Nutrients 708 27.2 Metabolism 711 27.3 Metabolism and Body Heat 719 28 THE URINARY SYSTEM 726 28.1 Overview of the Urinary System 727 28.2 Structure of the Kidneys 728 28.3 Functions of the Nephron 732 28.4 Transportation, Storage, and Elimination of Urine 737 28.5 Aging and the Urinary System 739 29.4 Female Reproductive Cycle 759 29.5 Aging and the Reproductive Systems 763 29 THE REPRODUCTIVE SYSTEMS 744 29.1 Introduction to the Reproductive Systems 745 29.2 Male Reproductive 29.3 Female Reproductive System 752 APPENDIX A: MEASUREMENTS A1 B: PERIODIC TABLE B3 C: ANSWERS C4 GLOSSARY G1 CREDITS CR1 INDEX I1

    2 in stock

    £193.46

  • Visualizing Anatomy and Physiology

    John Wiley & Sons Inc Visualizing Anatomy and Physiology

    10 in stock

    Book SynopsisVisualizing Anatomy and Physiology is a visually powerful textbook, illustrated for maximum pedagogical effect, up-to-the-minute in all aspects of anatomical science and physiology. Organized into 16 chapters, the material is designed to fit more easily into the shorter one-semester course. Chapters 1-16 provide motivating and engaging content as well as clinical and everyday relevance of the science of the discipline. This edition includes numerous assessment opportunities and tested visuals that are used to teach and explain, not just illustrate.Table of Contents1 Organization of the Human Body. 2 Introductory Chemistry. 3 Cells and Tissues. 4 The Integumentary System. 5 The Skeletal System. 6 The Muscular System. 7 The Nervous System. 8 Somatic Senses and Special Senses. 9 The Endocrine System. 10 The Cardiovascular System: Blood. 11 The Cardiovascular System: Heart, Blood Vessels, and Circulation. 12 The Lymphatic System and Immunity. 13 The Respiratory System. 14 The Digestive System, Nutrition, and Metabolism. 15 The Urinary System, Fluid, Electrolyte, and Acid-Base Balance. 16 The Reproductive Systems. Appendix A Periodic Table. Appendix B Measurements. Appendix C Answers to Self-Tests. Glossary. Line Art Credits. Photo Credits. Index.

    10 in stock

    £165.25

  • Anatomy and Physiology for the Manual Therapies

    John Wiley and Sons Ltd Anatomy and Physiology for the Manual Therapies

    10 in stock

    Book SynopsisTable of Contents1 Organization of the Human Body 1 1.1 Anatomy and Physiology Defined 2 1.2 Levels of Organization and Body Systems 2 1.3 Life Processes 6 1.4 Homeostasis: Maintaining Limits 8 Control of Homeostasis: Feedback Systems 8 Homeostasis and Good Health 9 1.5 Aging and Homeostasis 12 1.6 Anatomical Terms 12 Names of Body Regions 12 Directional Terms 12 Exhibit 1.1 Directional Terms 14 Planes and Sections 16 1.7 Body Cavities 17 Abdominopelvic Regions and Quadrants 18 1.8 Medical Imaging 20 Key Medical Terms Associated with the Organization of the Human Body 24 2 Introductory Chemistry 28 2.1 Introduction to Chemistry 29 Chemical Elements and Atoms 29 Ions, Molecules, and Compounds 30 Chemical Bonds 31 Chemical Reactions 34 2.2 Chemical Compounds and Life Processes 35 Inorganic Compounds 35 Organic Compounds 36 Carbohydrates 36 Lipids 38 Proteins 41 Nucleic Acids 43 Adenosine Triphosphate 43 3 Cells 47 3.1 A Generalized View of the Cell 48 3.2 Plasma Membrane 49 3.3 Transport Across the Plasma Membrane 50 Passive Processes 51 Active Processes 54 3.4 Cytoplasm 57 Cytosol 57 Organelles 57 3.5 Nucleus 63 3.6 Gene Action: Protein Synthesis 64 Transcription 66 Translation 66 3.7 Somatic Cell Division 68 Interphase 68 Mitotic Phase 68 3.8 Cancer 70 Growth and Spread of Cancer 70 Causes of Cancer 70 Carcinogenesis: A Multistep Process 71 Treatment of Cancer 71 3.9 Aging and Cells 72 Key Medical Terms Associated with Cells 72 4 Tissues 77 4.1 Types of Tissues 78 4.2 Cell Junctions 78 4.3 Epithelial Tissue 79 General Features of Epithelial Tissue 80 Covering and Lining Epithelium 80 Glandular Epithelium 88 4.4 Connective Tissue 89 General Features of Connective Tissue 90 Connective Tissue Cells 90 Connective Tissue Extracellular Matrix 91 Classification of Connective Tissues 92 Types of Mature Connective Tissue 92 Connective Tissues: Diverse and Dynamic 100 4.5 Membranes 101 Mucous Membranes 101 Serous Membranes 101 Synovial Membranes 101 4.6 Musular Tissue 102 4.7 Nervous Tissue 104 4.8 Tissue Repair: Restoring Homeostasis 105 4.9 Aging and Tissues 106 Excess Adiposity 106 Key Medical Terms Associated with Tissues 106 5 The Integumentary System 111 5.1 Structure of the Skin 112 Epidermis 113 Keratinization and Growth of the Epidermis 116 Dermis 116 Skin Color 117 5.2 Accessory Structures of the Skin 118 Hair 118 Skin Glands 121 Nails 122 5.3 Types of Skin 123 5.4 Functions of the Skin 124 5.5 Maintaining Homeostasis: Skin Wound Healing 125 Epidermal Wound Healing 125 Dermal Wound Healing 125 5.6 Skin Conditions Important to Therapists 127 Skin Cancer 127 Burns 128 Pressure Ulcers 129 5.7 Aging and the Integumentary System 130 Key Medical Terms Associated with the Integumentary System 130 Exhibit 5.1 The Integumentary System and Homeostasis 131 6 Bone Tissue 135 6.1 Functions of Bone and the Skeletal System 136 6.2 Structure of Bone 136 6.3 Histology of Bone Tissue 138 Compact Bone Tissue 139 Spongy Bone Tissue 139 6.4 Blood and Nerve Supply of Bone 141 6.5 Bone Formation 142 Intramembranous Ossification 142 Endochondral Ossification 142 6.6 Bone Growth 145 Growth in Length 145 Growth in Thickness 146 6.7 Bones and Homeostasis 147 Bone Remodeling 147 Factors Affecting Bone Growth and Bone Remodeling 148 Fracture and Repair of Bone 148 Bone’s Role in Calcium Homeostasis 151 6.8 Aging and Bone Tissue 152 Key Medical Terms Associated with Bone Tissue 154 7 The Skeletal System: The Axial Skeleton 159 7.1 Divisions of the Skeletal System 160 7.2 Types of Bones 160 7.3 Bone Surface Markings 162 7.4 Skull 162 General Features and Functions 163 Cranial Bones 164 Facial Bones 170 Nasal Septum 173 Orbits 174 Foramina 174 Unique Features of the Skull 174 7.5 Hyoid Bone 177 7.6 Vertebral Column 177 Normal Curves of the Vertebral Column 179 Intervertebral Discs 179 Parts of a Typical Vertebra 179 Regions of the Vertebral Column 180 7.7 Thorax 186 Sternum 186 Ribs 186 7.8 Disorders of the Axial Skeleton 189 Abnormal Curves of the Vertebral Column 189 Spina Bifida 190 Key Medical Terms Associated with Axial Skeleton 191 8 The Skeletal System: The Appendicular Skeleton 195 8.1 Pectoral (Shoulder) Girdle 196 Clavicle 196 Scapula 197 8.2 Upper Limb (Extremity) 199 Humerus 199 Ulna and Radius 201 Carpals, Metacarpals, and Phalanges 202 8.3 Pelvic (Hip) Girdle 205 Ilium 206 Ischium 206 Pubis 207 False and True Pelves 207 8.4 Comparison of Female and Male Pelves 209 8.5 Comparison of Pectoral and Pelvic Girdles 210 8.6 Lower Limb (Extremity) 211 Femur 211 Patella 213 Tibia and Fibula 214 Tarsals, Metatarsals, and Phalanges 215 Arches of the Foot 217 Exhibit 8.1 The Skeletal System and Homeostasis 218 Key Medical Terms Associated with Appendicular Skeleton 219 9 Joints 221 9.1 Joint Classifications 222 9.2 Fibrous Joints 222 Sutures 222 Syndesmoses 224 Interosseous Membranes 224 9.3 Cartilaginous Joints 224 Synchondroses 224 Symphyses 224 9.4 Synovial Joints 225 Structure of Synovial Joints 225 Bursae and Tendon Sheaths 227 Types of Synovial Joints 227 9.5 Types of Movements at Synovial Joints 230 Gliding 230 Angular Movements 230 Rotation 233 Special Movements 234 9.6 Selected Joints of the Body 236 Exhibit 9.1 Temporomandibular Joint 238 Exhibit 9.2 Shoulder Joint 240 Exhibit 9.3 Elbow Joint 243 Exhibit 9.4 Hip Joint 244 Exhibit 9.5 Knee Joint 246 Exhibit 9.6 Ankle Joint 249 9.7 Factors Affecting Contact and Range of Motion at Synovial Joints 251 9.8 Arthroplasty 252 9.9 Aging and Joints 253 Key Medical Terms Associated with Joints 253 10 Muscular Tissue 257 10.1 Overview of Muscular Tissue 258 Types of Muscular Tissue 258 Functions of Muscular Tissue 258 Properties of Muscular Tissue 259 10.2 Skeletal Muscle Tissue 259 Connective Tissue Components 259 Nerve and Blood Supply 261 Histology 261 10.3 Contraction and Relaxation of Skeletal Muscle Fibers 263 Sliding Filament Mechanism 263 Neuromuscular Junction 263 Physiology of Contraction 264 Relaxation 266 Muscle Tone 268 10.4 Metabolism of Skeletal Muscle Tissue 268 Energy for Contraction 268 Muscle Fatigue 268 Oxygen Consumption after Exercise 270 10.5 Control of Muscle Tension 270 Twitch Contraction 270 Frequency of Stimulation 271 Motor Unit Recruitment 271 Types of Skeletal Muscle Fibers 271 Isometric and Isotonic Contractions 272 10.6 Muscle Spasms 273 10.7 Exercise and Skeletal Muscle Tissue 277 Effective Stretching 277 Strength Training 277 10.8 Cardiac Muscle Tissue 277 10.9 Smooth Muscle Tissue 278 10.10 Aging and Muscular Tissue 279 Key Medical Terms Associated with Muscular Tissue 280 11 The Muscular System: The Muscles of the Head and Neck 284 11.1 How Skeletal Muscles Produce Movement 285 Muscle Attachment Sites: Origin and Insertion 285 Lever Systems and Leverage 285 Effects of Fascicle Arrangement 288 Coordination within Muscle Groups 288 11.2 How Skeletal Muscles Are Named 289 11.3 Principal Skeletal Muscles of the Head and Neck 289 Exhibit 11.1 Muscles of Facial Expression 294 Exhibit 11.2 Muscles that Move the Eyeballs and Upper Eyelids (Extrinsic Eye Muscles) 300 Exhibit 11.3 Muscles that Move the Mandible and Assist in Mastication (Chewing) and Speech 302 Exhibit 11.4 Muscles of the Anterior Neck that Assist in Deglutition (Swallowing) and Speech 304 Exhibit 11.5 Muscles of the Anterior Neck that Assist in Elevating the Ribs or Flexing the Neck and Head 307 Exhibit 11.6 Muscles of the Lateral Neck that Move the Head 310 12 The Muscular System: The Muscles of the Torso 316 Exhibit 12.1 Muscles of the Abdoman that Act on the Abdominal Wall 317 Surface Features of the Abdomen and Pelvis 320 Exhibit 12.2 Muscles of the Thorax Used in Breathing 324 Exhibit 12.3 Muscles of the Pelvic Diaphragm and Perineum that Support the Pelvic Viscera 325 Exhibit 12.4 Muscles of the Neck and Back that Act on the Posterior Head, Posterior Neck, Back, and Vertebral Column 328 Suboccipital Muscles 332 13 The Muscular System: The Muscles of the Upper Limb 336 Exhibit 13.1 Muscles of the Thorax that Move the Pectoral Girdle 337 Movements of the Scapula 340 Exhibit 13.2 Muscles of the Thorax and Shoulder that Move the Humerus 341 Surface Features of the Shoulder 341 Surface Features of the Armpit 341 Surface Features of the Back 346 Exhibit 13.3 Muscles of the Arm that Move the Radius and Ulna 347 Surface Features of the Arm and Elbow 352 Exhibit 13.4 Muscles of the Forearm that Move the Wrist, Hand, and Digits 354 Exhibit 13.5 Muscles of the Palm that Move the Digits–Intrinsic Muscles of the Hand 362 Surface Features of the Hand 366 14 The Muscular System: The Muscles of the Lower Limb 369 14.1 Introduction to the Muscles of the Lower Limb (Extremity) 370 Exhibit 14.1 Muscles of the Gluteal Region that Move the Femur 371 Surface Features of the Buttock 378 Exhibit 14.2 Muscles of the Thigh that Move on the Femur, Tibia, and Fibula 380 Surface Features of the Thigh and Knee 383 Exhibit 14.3 Muscles of the Leg that Move the Foot and Toes 386 Surface Features of the Leg, Ankle, and Foot 391 Exhibit 14.4 Intrinsic Muscles of the Foot that Move the Toes 393 14.2 Muscle Interactions 398 The Interconnectedness of the Whole Body 398 Posture and Interactions between Muscles 398 Exhibit 14.5 Contributions of the Muscular System to Homeostasis 400 15 Nervous Tissue 403 15.1 Overview of the Nervous System 404 Structures of the Nervous System 404 Functions of the Nervous System 404 Organization of the Nervous System 405 15.2 Histology of Nervous Tissue 407 Neurons 407 Myelination 409 Gray and White Matter 411 Neuroglia 411 15.3 Electrical Signals in Neurons 413 Action Potentials 413 Conduction of Nerve Impulses 417 Effect of Axon Diameter 418 15.4 Synaptic Transmission 418 Events at a Synapse 418 Neurotransmitters 420 15.5 Regeneration and Repair of Nervous Tissue 421 Neurogenesis in the CNS 421 Damage and Repair in the PNS 421 Key Medical Terms Associated with Nervous Tissue 422 16 The Spinal Cord and Spinal Nerves 426 16.1 Spinal Cord Anatomy 427 Protective Structures 427 External Anatomy of the Spinal Cord 427 Internal Anatomy of the Spinal Cord 429 16.2 Spinal Nerves 430 Connective Tissue Coverings of Spinal Nerves 432 Distribution of Spinal Nerves 433 Exhibit 16.1 Cervical Plexus 434 Exhibit 16.2 Brachial Plexus 436 Exhibit 16.3 Lumbar Plexus 440 Exhibit 16.4 Sacral and Coccygeal Plexuses 442 Dermatomes 444 16.3 Spinal Cord Physiology 444 Sensory and Motor Tracts 445 Reflexes and Reflex Arcs 449 Reflexes and Diagnosis 457 16.4 Traumatic Injuries of the Spinal Cord 458 Key Medical Terms Associated with the Spinal Cord and Spinal Nerves 458 17 The Brain and Cranial Nerves 463 17.1 The Brain 464 Major Parts and Protective Coverings 464 Brain Blood Supply and the Blood-Brain Barrier 464 Cerebrospinal Fluid 464 Brain Stem 468 Diencephalon 469 Cerebellum 471 Cerebrum 471 Hemispheric Lateralization 476 Memory 476 Electroencephalogram (EEG) 476 17.2 Cranial Nerves 477 17.3 Aging and the Nervous System 479 Key Medical Terms Associated with the Brain 479 18 The Autonomic Nervous System 483 18.1 Introduction to the Autonomic Nervous System 484 18.2 Comparison of Somatic and Autonomic Nervous Systems 484 18.3 Structure of the Autonomic Nervous System 486 Organization of the Sympathetic Division 486 Organization of the Parasympathetic Division 488 18.4 Functions of the Autonomic Nervous System 491 ANS Neurotransmitters 491 Activities of the ANS 491 18.5 Integration and Control of Autonomic Functions 492 Autonomic Reflexes 492 Autonomic Control by Higher Centers 494 Key Medical Terms Associated with the Autonomic Nervous System 494 19 Somatic and Special Senses 498 19.1 Overview of Sensations 499 Definition of Sensation 499 Characteristics of Sensations 499 Types of Sensory Receptors 499 19.2 Somatic Senses 500 Tactile Sensations 500 Thermal Sensations 501 Pain Sensations 502 Proprioceptive Sensations 503 19.3 Special Senses and Olfaction: Sense of Smell 504 Structure of the Olfactory Epithelium 504 Stimulation of Olfactory Receptors 505 The Olfactory Pathway 505 19.4 Gustation: Sense of Taste 506 Structure of Taste Buds 506 Stimulation of Gustatory Receptors 506 The Gustatory Pathway 506 19.5 Vision 507 Accessory Structures of the Eye 507 Layers of the Eyeball 509 Interior of the Eyeball 511 Image Formation and Binocular Vision 512 Stimulation of Photoreceptors 514 The Visual Pathway 514 19.6 Hearing and Equilibrium 515 Anatomy of the Ear 515 Physiology of Hearing 518 Auditory Pathway 519 Deafness 519 Physiology of Equilibrium 519 Equilibrium Pathways 519 Reflexology via the Ear 519 19.7 Aging and the Special Senses 521 Key Medical Terms Associated with Somatic and Special Senses 522 Exhibit 19.1 Contributions of the Nervous System to Homeostasis 523 20 The Endocrine System 527 20.1 Endocrine Glands 528 20.2 Hormone Action 528 Target Cells and Hormone Receptors 528 Chemistry of Hormones 528 Mechanisms of Hormone Action 528 Control of Hormone Secretions 528 20.3 Hypothalamus and Pituitary Gland 530 Anterior Pituitary Hormones 531 Posterior Pituitary Hormones 533 20.4 Thyroid Gland 535 Actions of Thyroid Hormones 535 Control of Thyroid Hormone Secretion 536 Calcitonin 537 20.5 Parathyroid Glands 538 20.6 Pancreatic Islets 539 Actions of Glucagon and Insulin 540 20.7 Adrenal Glands 542 Adrenal Cortex Hormones 543 Adrenal Medulla Hormones 545 20.8 Ovaries and Testes 545 20.9 Pineal Gland 545 20.10 Other Hormones 546 Hormones from Other Endocrine Cells 546 Prostaglandins and Leukotrienes 546 20.11 The Stress Response 547 20.12 Aging and the Endocrine System 547 Key Medical Terms Associated with the Endocrine System 548 Exhibit 20.1 Contributions of the Endocrine System to Homeostasis 549 21 The Cardiovascular System: The Blood 553 21.1 Functions of Blood 554 21.2 Components of Whole Blood 554 Blood Plasma 554 Formed Elements 554 21.3 Hemostasis 563 Vascular Spasm 564 Platelet Plug Formation 564 Blood Clotting 564 Hemostatic Control Mechanisms 566 Clotting in Blood Vessels 566 21.4 Blood Groups and Blood Types 566 ABO Blood Group 567 Rh Blood Group 567 Transfusions 568 Key Medical Terms Associated with Blood 568 22 The Cardiovascular System: The Heart 571 22.1 Structure and Organization of the Heart 572 Location and Coverings of the Heart 572 Heart Wall 575 Chambers of the Heart 575 Great Vessels of the Heart 577 Valves of the Heart 577 22.2 Blood Flow and Blood Supply of the Heart 579 Blood Flow through the Heart 579 Blood Supply of the Heart 579 Myocardial Ischemia and Infarction 580 22.3 Conduction System of the Heart 581 22.4 Electrocardiogram 583 Arrhythmias 583 22.5 The Cardiac Cycle 584 Pressure and Volume Changes during the Cardiac Cycle 584 Heart Sounds 586 22.6 Cardiac Output 586 Regulation of Stroke Volume 586 Regulation of Heart Rate 589 22.7 Exercise and the Heart 590 Key Medical Terms Associated with the Heart 590 23 The Cardiovascular System: Blood Vessels and Circulation 594 23.1 Blood Vessel Structure and Function 595 Arteries and Arterioles 595 Capillaries 595 Venules and Veins 597 23.2 Blood Flow Through Blood Vessels 599 Blood Pressure 599 Resistance 600 Regulation of Blood Pressure and Blood Flow 600 23.3 Checking Circulation 603 Pulse 603 Measurement of Blood Pressure 603 23.4 Circulatory Routes 603 Systemic Circulation 603 Pulmonary Circulation 605 Exhibit 23.1 The Aorta and Its Branches 606 Exhibit 23.2 The Arch of the Aorta 608 Exhibit 23.3 Arteries of the Pelvis and Lower Limbs 610 Exhibit 23.4 Veins of the Systemic Circulation 612 Exhibit 23.5 Veins of the Head and Neck 614 Exhibit 23.6 Veins of the Upper Limbs 615 Exhibit 23.7 Veins of the Lower Limbs 617 Hepatic Portal Circulation 619 Fetal Circulation 620 23.5 Aging and the Cardiovascular System 620 Exhibit 23.8 Contributions of the Cardiovascular System to Homeostasis 622 Key Medical Terms Associated with Blood Vessels 623 24 The Lymphatic System and Immunity 627 24.1 Overview of Immunity 628 24.2 Lymphatic System Structure and Function 628 Lymphatic Vessels and Lymph Circulation 628 Lymphatic Organs and Tissues 631 24.3 Innate Immunity 634 First Line of Defense: Skin and Mucous Membranes 634 Second Line of Defense: Internal Defenses 634 24.4 Adaptive Immunity 636 Maturation of T cells and B cells 637 Types of Adaptive Immune Responses 637 Antigens and Antibodies 637 Processing and Presenting Antigens 638 T Cells and Cell-Mediated Immunity 639 B Cells and Antibody-Mediated Immunity 642 Immunological Memory 643 24.5 Aging and the Immune System 645 Exhibit 24.5 Contributions of the Lymphatic System and Immunity to Homeostasis 646 Key Medical Terms Associated with the Lymphatic System 647 25 The Respiratory System 651 25.1 Overview of the Respiratory System 652 25.2 Organs of the Respiratory System 653 Nose 653 Pharynx 654 Larynx 654 Trachea 656 Bronchi and Bronchioles 656 Lungs 657 25.3 Pulmonary Ventilation 660 Muscles of Inhalation and Exhalation 661 Pressure Changes During Ventilation 662 Lung Volumes and Capacities 662 Breathing Patterns and Modified Respiratory Movements 664 25.4 Exchange of Oxygen and Carbon Dioxide 664 External Respiration: Pulmonary Gas Exchange 665 Internal Respiration: Systemic Gas Exchange 665 25.5 Transport of Respiratory Gases 667 Oxygen Transport 667 Dioxide Transport 667 25.6 Control of Respiration 667 Respiratory Center 668 Regulation of the Respiratory Center 669 25.7 Exercise and the Respiratory System 671 25.8 Aging and the Respiratory System 671 Exhibit 25.1 Contributions of the Respiratory System to Homeostasis 672 Key Medical Terms Associated with the Respiratory System 673 26 The Digestive System 677 26.1 Overview of the Digestive System 678 26.2 Layers of the GI Tract and the Peritoneum 679 26.3 Mouth 681 Tongue 681 Salivary Glands 682 Teeth 682 Digestion in the Mouth 683 26.4 Pharynx and Esophagus 683 26.5 Stomach 685 Structure of the Stomach 686 Digestion and Absorption in the Stomach 687 26.6 Pancreas 688 Structure of the Pancreas 688 Pancreatic Juice 688 26.7 Liver and Gallbladder 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