Physiology Books

Book SynopsisA classic of modern gross scholarship.Complete with hilariously disgusting illustrations and fun activities, this guide to all things gross covers everything from barf to farts to scabs. Discover the science behind the sickeningly cool stuff that comes out of our bodies!

Read more less

Book SynopsisUses clinical case studies to promote interactive learning and to build a foundation of knowledge for clinical practice. This title includes various cases that present an unknown clinical disorder and examines differential diagnoses, treatments, and outcomes as well as relevant physiologic principles for a well-rounded review.

Read more less

Book Synopsis1 The Cardiac Conducting System and Its Autonomic Control.- Anatomy of the Conducting System.- Autonomic Innervation of the Heart.- 2 The Pathophysiology of Atrial Fibrillation.- Pathology.- The Electrophysiology of Atrial Fibrillation.- The Ventricular Response in Atrial Fibrillation.- The Role of the Autonomic Nervous System in Atrial Fibrillation.- Fibrillatory Waves in Atrial Fibrillation.- The Brody Phenomenon in Atrial Fibrillation.- The QT Interval in Atrial Fibrillation.- Atrial Fibrillation and the Wolff-Parkinson-White Syndrome.- Aberration in Atrial Fibrillation.- 3 Models of the Atrioventricular Node.- The Electrophysiological Model of the Atrioventricular Node.- Analogue Models of the Atrioventricular Node.- Mathematical Models of the Atrioventricular Node in Atrial Fibrillation.- The Atrioventricular Node as a Biological Oscillator.- More Electrophysiological Phenomena: Ventricular Extrasystoles.- Phase Resetting: An Achilles Heel.- 4 The Measurement of Cardiac Output in Sinus Rhythm and Atrial Fibrillation.- Assessment of Cardiac Function.- The Assessment of Cardiovascular Function.- Measuring Volumetric Cardiac Output by the Fick Method..- The Indirect Fick Technique.- Thermodilution.- Reproducibility of Thermodilution.- Measurement of Cardiac Output by Echocardiography and Doppler Ultrasound.- Linear Cardiac Output.- Expectations of Linear Cardiac Output.- Comparison between Thermodilution and Doppler Ultrasound.- Application of Linear Cardiac Output Measurement to Atrial Fibrillation.- Average Stroke and Minute Distance in Atrial Fibrillation.- Beat-to-Beat Measurement of Stroke Output.- 5 The Haemodynamics of Atrial Fibrillation: The Development of a Model of Left Ventricular Function.- The Relationship Between Time and Volume of the Pulse.- Derivation of a Mathematical Model of Left Ventricular Function.- The Physiological Basis for the Mathematical Model of Left Ventricular Function.- Application of the Mathematical Model of Left Ventricular Function.- Haemodynamic Consequences of Atrial Fibrillation.- Endocrine Consequences of Atrial Fibrillation.- 6 The Haemodynamics of Atrial Fibrillation: The Effect of Ventricular Rate on Cardiac Output.- Further Information from Multiple Regression Analysis.- The Ventricular Rate for Maximum Cardiac Output.- What is Meant by Control of Ventricular Rate?.- 7 The Use of the Haemodynamic Model of Atrial Fibrillation for Evaluating Drug Action.- More Haemodynamic Profiles.- Additional Haemodynamic Data Derived from Stroke Distance.- A Pilot Study of the Effect of Enoximone in Atrial Fibrillation.- A Placebo Controlled Trial of Enoximone and Digoxin in Atrial Fibrillation.- Conclusions.- 8 The Autonomic Control of Ventricular Rate in Atrial Fibrillation.- Respiratory Sinus Arrhythmia.- Measurement of Baroreflex Function.- A Systems Approach to Heart Rate Control.- Conclusions.- 9 Clinical Aspects of Atrial Fibrillation.- Epidemiology.- Aetiology.- Thromboembolism.- 10 The Management of Atrial Fibrillation.- Presentation.- Control of Ventricular Rate.- Cardioversion.- Chemical Cardioversion and Prevention of Atrial Fibrillation.- Anticoagulant Therapy.- The Wolff-Parkinson-White Syndrome.- New and Experimental Techniques in Atrial Fibrillation Pacing.- Appendix. A Simple Computer Model of the Electrophysiological System of the Heart, Considering the Sinoatrial and Atrioventricular Nodes as Sine Wave Oscillators.Table of Contents1 The Cardiac Conducting System and Its Autonomic Control.- Anatomy of the Conducting System.- Basic Cardiac Electrophysiology.- The Initiation and Propagation of the Cardiac Impulse.- Resetting the Sinoatrial Node Pacemaker.- The Spread of the Impulse Through the Atria.- The Functioning of the Atrioventricular Node.- Does the Atrioventricular Node Conduct?.- Autonomic Innervation of the Heart.- Autonomic Control of the Sinoatrial Node.- Autonomic Control of the Atrioventricular Node.- 2 The Pathophysiology of Atrial Fibrillation.- Pathology.- The Electrophysiology of Atrial Fibrillation.- Electrophysiological Factors that Predispose to Atrial Fibrillation.- Initiation of Atrial Fibrillation.- The Mapping of Atrial Flutter and Fibrillation: The Essential Distinction Between Them.- The Ventricular Response in Atrial Fibrillation.- The Input to the Atrioventricular Node.- The Ventricular Response in Atrial Fibrillation.- The Role of the Autonomic Nervous System in Atrial Fibrillation.- Autocorrelation and the Baroflex.- Fibrillatory Waves in Atrial Fibrillation.- The Brody Phenomenon in Atrial Fibrillation.- The QT Interval in Atrial Fibrillation.- Is the QT Interval in Atrial Fibrillation Different from that in Sinus Rhythm?.- Atrial Fibrillation and the Wolff-Parkinson-White Syndrome.- Aberration in Atrial Fibrillation.- 3 Models of the Atrioventricular Node.- The Electrophysiological Model of the Atrioventricular Node.- Analogue Models of the Atrioventricular Node.- Mathematical Models of the Atrioventricular Node in Atrial Fibrillation.- The Model of Cohen et al. (1983).- The Atrioventricular Node as a Biological Oscillator.- The Model of Guevara and Glass (1982).- Resetting the Oscillator.- The Response of a Sine-Wave Oscillator to a Rapid Random Input.- The Effect of a Refractory Period on the Behaviour of the Sine-Wave Model of the Atrioventricular Node.- What Values Should Be Assigned to the Sine-Wave Model’s Parameters?.- More Electrophysiological Phenomena: Ventricular Extrasystoles.- The “Compensatory Pause” in Atrial Fibrillation.- Peeling Back Refractoriness.- The Effect of Right Ventricular Pacing in Atrial Fibrillation.- The Wolff-Parkinson-White Syndrome.- Conclusions.- Phase Resetting: An Achilles Heel.- 4 The Measurement of Cardiac Output in Sinus Rhythm and Atrial Fibrillation.- Assessment of Cardiac Function.- The Assessment of Cardiovascular Function.- Measuring Volumetric Cardiac Output by the Fick Method..- The Indirect Fick Technique.- Thermodilution.- Reproducibility of Thermodilution.- Measurement of Cardiac Output by Echocardiography and Doppler Ultrasound.- Measurement of Aortic Cross-Sectional Area.- Measurement of Stroke Distance.- Linear Cardiac Output.- Relationship Between Body Surface Area and Aortic Cross-Sectional Area.- Effect of Age and Blood Pressure on Aortic Size and Stroke Distance.- Expectations of Linear Cardiac Output.- Comparison between Thermodilution and Doppler Ultrasound.- Relationship Between Linear and Volumetric Cardiac Output.- Application of Linear Cardiac Output Measurement to Atrial Fibrillation.- Average Stroke and Minute Distance in Atrial Fibrillation.- Beat-to-Beat Measurement of Stroke Output.- 5 The Haemodynamics of Atrial Fibrillation: The Development of a Model of Left Ventricular Function.- The Relationship Between Time and Volume of the Pulse.- Is Pulse Volume Irregularly Irregular?.- Derivation of a Mathematical Model of Left Ventricular Function.- The Physiological Basis for the Mathematical Model of Left Ventricular Function.- Effect of RR—1 on Stroke Distance: Preload.- Effect of RR—1 on Stroke Distance: Contractility.- The Effect of RR-1 on Stroke Distance: Afterload.- Effect of RR-2 on Stroke Distance.- Balance of Effects of RR-1 and RR-2.- Pulsus Alternans.- Application of the Mathematical Model of Left Ventricular Function.- Graphical Presentation of Multiple Regression Equation.- Haemodynamic Consequences of Atrial Fibrillation.- Venous Return.- Ventricular Filling.- Mitral Regurgitation.- Coronary Blood Flow.- Regional Blood Flow.- Systolic Time Intervals.- Endocrine Consequences of Atrial Fibrillation.- 6 The Haemodynamics of Atrial Fibrillation: The Effect of Ventricular Rate on Cardiac Output.- Further Information from Multiple Regression Analysis.- Three Haemodynamic Profiles.- Relationship between Stroke and Minute Output.- The Contribution of the Force-Frequency Effect to Maintenance of Cardiac Output at High Ventricular Rates.- The Predicted Effect of Heart Rate on Cardiac Output in Mitral Stenosis.- Effect of Irregularity Per Se on Cardiac Output.- The Ventricular Rate for Maximum Cardiac Output.- The Predicted Ventricular Rate for Maximal Cardiac Output 122 Relationship Between Slope of the Md/Mean VR Graph and Ventricular Rate.- Group Relationship Between Mean R-R Interval and Stroke Distance.- The Magnitude of the Effect of Ventricular Rate on Cardiac Output.- The Ventricular Rate for Maximum Cardiac Output: Sinus Rhythm.- Comparison of Atrial Fibrillation and Sinus Rhythm.- What is Meant by “Control” of Ventricular Rate?.- A New Concept of Control of the Ventricular Rate in Atrial Fibrillation.- 7 The Use of the Haemodynamic Model of Atrial Fibrillation for Evaluating Drug Action.- More Haemodynamic Profiles.- Additional Haemodynamic Data Derived from Stroke Distance.- A Pilot Study of the Effect of Enoximone in Atrial Fibrillation.- The Effect of Enoximone on the Haemodynamic Model.- Control of Ventricular Rate While on Enoximone.- A Placebo Controlled Trial of Enoximone and Digoxin in Atrial Fibrillation.- Conclusions.- 8 The Autonomic Control of Ventricular Rate in Atrial Fibrillation.- Respiratory Sinus Arrhythmia.- Quantifying Respiratory Sinus Arrhythmia.- Cheyne-Stokes Respiration.- Respiratory Variation of P-R Intervals.- Modelling the Effect of the Vagus on the Atrioventricular Node.- Respiratory Variation of Ventricular Rate in Atrial Fibrillation.- Modelling the Action of the Vagus on the Ventricular Response to Atrial Fibrillation.- Measurement of Baroreflex Function.- Ramp Method.- Neck-Suction Method.- Integration of Respiratory Sinus Arrhythmia and the Baroreflex.- The Frequency Response of the Heart Rate Control System.- A Systems Approach to Heart Rate Control.- The Effect of Ventricular Rate on Blood Pressure in Atrial Fibrillation.- The Effect of Ventricular Rate on Blood Pressure in Sinus Rhythm.- Regulation of Ventricular Rate in Atrial Fibrillation.- Conclusions.- 9 Clinical Aspects of Atrial Fibrillation.- Epidemiology.- Incidence.- Prevalence.- Prognosis.- Aetiology.- Coronary Artery Disease.- Myocardial Infarction.- Valvular Heart Disease.- Thyrotoxicosis.- Alcohol.- Metabolic Causes of Atrial Fibrillation.- The Role of the Autonomic Nervous System in Precipitating Atrial Fibrillation.- Physical Factors Precipitating Atrial Fibrillation.- Iatrogenic Atrial Fibrillation.- Self-Induced Atrial Fibrillation.- Congenital and Familial Causes of Atrial Fibrillation.- Infection and Infestation.- Malignancy.- Connective Tissue Disorders.- The Acute Abdomen.- Neurological Conditions.- Respiratory and Sundry Conditions.- Spontaneous Termination of Atrial Fibrillation.- Thromboembolism.- Prevalence of Thromboembolism in Atrial Fibrillation.- Prevalence of Atrial Fibrillation in Thromboembolism.- Prevalence of Stroke in Atrial Fibrillation.- The Prevalence of Atrial Fibrillation in Stroke.- Intracardiac Thrombi in Atrial Fibrillation.- 10 The Management of Atrial Fibrillation.- Presentation.- Symptoms.- Signs.- Investigations.- General Management.- Control of Ventricular Rate.- Digitalis.- Beta-adrenergic Blockers.- Calcium Antagonists.- Cardioversion.- Selection of Patients for Cardioversion.- Complications of Cardioversion.- Physiological Consequences of Cardioversion.- Long-Term Results of Cardioversion.- Chemical Cardioversion and Prevention of Atrial Fibrillation.- Quinidine.- Calcium Antagonists.- Disopyramide.- Propafenone.- Digoxin.- Beta-adrenergic Blockers.- Amiodarone.- Flecainide and Other Class 1 Agents.- Anticoagulant Therapy.- Rheumatic Valve Disease.- Non-rheumatic Atrial Fibrillation.- Cardioversion.- The Wolff-Parkinson-White Syndrome.- New and Experimental Techniques in Atrial Fibrillation Pacing.- Internal Cardioversion.- His Bundle Ablation.- Surgical Treatment for Atrial Fibrillation.- Appendix. A Simple Computer Model of the Electrophysiological System of the Heart, Considering the Sinoatrial and Atrioventricular Nodes as Sine Wave Oscillators.

Read more less

Book Synopsis

Read more less

Book SynopsisThe ability to regulate and manipulate the generation or remodeling of blood vessels is key to the successful treatment of many chronic diseases, both oncological and non-oncological. Several bioactive compounds present in human diets are now known to exert an inhibitive effect on the either the signaling or construction of new blood vessels. The identification and characterization of these anti-angiogenic molecules opens a new avenue for the research and production of functional and medicinal foods with far reaching implications for the food-based treatment of chronic degenerative disease.Drawing from an extensive list of esteemed international contributors, Anti-Angiogenic Functional and Medicinal Foods explores the history and scope of the use of conventional foods, nutraceuticals, and health products in North America, Europe, the Middle East, Asia, India, Australia, and New Zealand. Recent advancements in proteomics, genomics, and toxicogenomics give us a far more detailed picture of the molecular basis of nutrition and systems toxicology. Explaining the role of angiogenesis in various chronic diseases, individual chapters consider endothelial cell responses, the mechanism of the angiogenic cascade, and the angiogenic function involved in tumors, cardiovascular disease, inflammatory arthritis, and obesity. A collection of chapters studies specific foods and their functional bioactive compounds such as the effects of edible berry anthocyanins, various Chinese medicinal foods, dietary flavonoids, probiotics, shark cartilage, EPA and DHA, and marine polysaccharides. The book concludes with a discussion of the challenges faced during the development and delivery of anti-angiogenic functional food products. Presenting the current research and state of the science, Anti-Angiogenic Functional and Medicinal Foods provides researchers, scientists, clinical nutritionists, and oncologists with a valuable reference to this important and growing mode ofTable of ContentsHistory and Scope of Functional Foods Around the World; The “Ohmics” Technologies and Functional Foods;Angiogenesis and Chronic Degenerative Diseases;Angiogenesis, Functional, and Medicinal Foods

Read more less

Book Synopsis

Read more less

Book SynopsisYour cells are talking about you. Right now, both your inner and outer worlds are abuzz with chatter among living cells of every possible kind—from those in your body and brain to those in the environment around you. From electrical alerts to chemical codes, the greatest secret of modern biology, hiding in plain sight, is that all of life's activity boils down to one thing: conversation. While cells are commonly considered the building block of living things, it is actually the communication between cells that brings us to life, controlling our bodies and brains, determining whether we are healthy or sick, and directly influencing how we think, feel, and behave. In The Secret Language of Cells, doctor and neuroscientist Jon Lieff lets us listen in on these conversations, and reveals their significance for everything from mental health to cancer. He explains the surprising science of how very different cells—bacteria and brain cells, blood cells and viruses—all speak the same language. This overarching principle has been long overlooked because scientific journals use impenetrable jargon that makes it hard to be understood across disciplines, much less by the general public. Lieff presents a fascinating and accessible look into cellular communication science—a groundbreaking and comprehensive exploration of this biological phenomenon. In these pages, discover the intriguing lives of cells as they ask questions, get answers, give feedback, gather information, call for each other, and make complex decisions. During infections, immune T-cells tell brain cells that we should "feel sick" and lie down. Cancer cells warn their community about immune and microbe attacks. Gut cells talk with microbes to determine which are friends and which are enemies, and microbes talk with each other and with much more complicated human cells in ways that determine which medicines work and which will fail. With applications for immunity, chronic pain, weight loss, depression, cancer treatment, and virtually every aspect of health and biology, cellular communication is revolutionizing our understanding not just of disease, but of life itself. The Secret Language of Cells is required reading for anyone interested in following the conversation.Trade Review"Using the common theme of 'cellular conversations,' this book covers an astonishing breadth of biological topics. By removing most of the 'impenetrable jargon' from his descriptions, geriatric psychiatry specialist Lieff succeeds in making the complex interactions between cells accessible for most readers." —Choice Reviews "The Secret Language of Cells takes us on an exciting journey into a world where we can visualize elaborate conversations among immune cells, brain cells, gut cells, bacteria, and even viruses. Dr. Lieff gives a wealth of examples for his thesis that this cellular signaling is the basis of life. It is a must-read for anyone seeking to understand modern biology and advanced medical science." —Ray Kurzweil, inventor, author, and futurist "The Secret Language of Cells explains the complex ways that cells in the body communicate and presents a new paradigm for understanding health and disease. It also suggests new possibilities for treatment and for promoting healing. I'm pleased that my former Harvard colleague, Jon Lieff, has written this important book." —Andrew Weill, MD, director of the Andrew Weil Center for Integrative Medicine, professor at University of Arizona College of Medicine, and author "Through a brilliant synthesis of cellular biology, microbiology, immunology, and neuroscience, TheSecret Language of Cells offers a lucid explanation of the marvelous intricacies of cellular life. The result is a masterful exploration of the profound implications of cellular intelligence for understanding pathophysiology, human health, and even our origins." —William B. Miller, Jr., MD, physician, biologist, author of The Microcosm Within: Evolution and Extinction in the Hologenome, and internationally recognized expert on Cognition-Based Evolution "Jon Lieff's description of cellular communication is insightful, provocative, illuminating, and engaging and provides deep and novel observations into the remarkable symphony of how life happens. Mimicking the cellular world he describes, Dr. Lieff is the great communicator and muse of living things. An inspiring and informative read." —Ted Kaptchuk, professor of medicine at Harvard Medical School "This journey into the dynamic realm of cellular conversations is a tour-de-force—fascinating, vital, and especially timely for understanding emerging viruses. As we learn about intelligence in smaller and smaller animals, it's not surprising that the tiniest creatures—microbes and even viruses—exhibit elaborate communication and complex decision making. Read The Secret Language of Cells!" —Marc Bekoff, PhD, professor emeritus of ecology and evolutionary biology at the University of Colorado, Boulder and author of Canine Confidential: Why Dogs Do What They Do "The Secret Language of Cells reveals how the micro world reflects the macro, alive with heroes and villains, shapeshifters and tricksters, vigilant guards and gullible bystanders, helpers that commit suicide for the common good and warriors that seize the day or collapse from exhaustion. Lieff's fascinating exploration inspires awe for the astonishing dialogues and clarion calls at the heart of the intelligence within." —Antonia Felix, EdD, MFA, New York Times bestselling author "Calling all physicians, microbiologists, medical students, and fellow science enthusiasts—you're going to love The Secret Language of Cells!This book reveals fascinating ongoing conversations between cells, bacteria, and viral particles that provide the basis for understanding growth, development, healthy biology, and pathology. Perhaps more importantly, they provide the blueprint for novel interventions, treatments, and cures for ailments ranging from chronic inflammatory diseases, to cancers and even viral infections. The COVID-19 pandemic has focused the world's lens on the world of microbes like never before. Read this book and join the conversation." —Jill Grimes, MD, family physician, speaker, author, and educator "The Secret Language of Cells is ideal for the education of medical and science students, as well as for practicing physicians. Dr. Lieff's remarkable synthesis of the scientific literature provides a current view of the intricate communication systems determining our physiology. He clearly explains how conversations among cells are the bridge between immunology, neuroscience, microbiology, and cancer research." —Sharon Redd, MD, senior associate in anesthesia at Boston Children's Hospital and assistant professor in anesthesia at Harvard Medical School "In TheSecret Language of Cells, Dr. Lieff, brilliantly and effectively, communicates the complexities of modern biology to clinicians, and even laypeople, in understandable terms. In the process, he elucidates how communications between diverse varieties of cells determine our physical, mental, and emotional health, as well as the potential social implications." —Sanford Finkel MD, founder of AAGP, cofounder of IPA and APA Council on Aging, and clinical professor of Psychiatry at University of Chicago Medical School "Dr. Jon Lieff's The Secret Language of Cells is a tour-de-force . . . I highly recommend this fascinating book to science readers and anyone wanting to better understand the role and importance of cellular functions and communications in health and disease." —George T. Grossberg, MD, director of Geriatric Psychiatry for the Department of Psychiatry & Behavioral Neuroscience at Saint Louis University School of Medicine "Dr. Lieff has synthesized an extensive literature on the biological communications that underlie life into a highly accessible book. His integrative summary will appeal to a broad audience, from high school biology students to professionals with specific areas of expertise." —Barnett Meyers, MD, professor emeritus at Weill Cornell Medical College of Cornell University "The Secret Language of Cells makes it possible for a healthy dialogue between biology and philosophy, a step closer to making a bridge between life-science and various monistic and non-dual philosophies." —Dr. Sthaneshwar Timalsina, professor for the Department of Religious Studies at San Diego State University

Read more less

Book SynopsisJennifer Pilotti's latest book explores the science at the intersection of movement and mental health. It encourages readers to consider in greater detail the way exercise impacts the nervous system, and how it influences the ability to sense, feel and perceive the internal and external world.Based on the author's extensive experience in both researching and teaching movement therapies, the book is designed to be accessible to practitioners and professionals across a range of disciplines. From Yoga and Tai Chi to dance teaching and personal training, the coaching guidance provided can also help therapists of all kinds think about the use of language, potential roadblocks and exercise interventions and programming in new ways.By examining key topics including aerobic exercise, resistance training and restorative movement, this book is a valuable resource for all kinds of practitioners looking for inventive ways to help their clients achieve physical and emotional balance.Trade ReviewJenn does an incredible job explaining the connections between exercise and mental health, while also providing practical application. A must read if you or your clients experience anxiety, stress, or chronic pain. -- Nikki Naab-Levy, B.S. Exercise Science

Read more less

Book SynopsisThis book spans topics in both congenital and acquired right heart disease providing readers with detailed information on the physiology, anatomy and myocardial mechanics of the right ventricle (RV), while describing the use of echo and MRI imaging to diagnose, and new developments in surgery and cardiac catheterization to treat. Right Ventricular Physiology, Adaptation and Failure in Congenital and Acquired Heart Disease includes extensive discussion of RV-pulmonary interactions, pulmonary hypertension and ventricular-ventricular interactions, including specific topics in embryology, fetal RV function, RV mechanics, pathophysiology of RV adaptation/ failure, molecular aspects of RV dysfunction, congenital heart disease, pulmonary arterial hypertension, pulmonary valve replacement, stem cell and future therapies.​ It is thus important reading for all cardiovascular medicine professionals, but especially pediatric cardiologists and surgeons, those who manage these patients in the cardiac care unit and investigators studying the RV. Table of ContentsIntroduction.- Embryological origins: How does the RV form?.- The fetal RV: systemic powerhouse or prone to fail?.- Metabolism and bioenergetics in the hypertrophied RV: what is different from the LV?.- Why does the RV myocardium fail?.- Does the RV really contract differently from the LV?.- How does the pressure loaded RV adapt and why does it fail? Macro and molecular perspectives.- Novel mechanisms of lung injury and repair in PAH: does success in the lab translate to hope for our patients?.- Right-left ventricular interactions in PAH.- From M-mode to 3D echo:-what should we use to assess RV function?.- What does MRI offer beyond volumes?.- Why is the RV different in TOF and in ASD?.- RV dyssynchrony and cardiac resynchronization therapy: New insights into mechanisms and pathophysiology.- The single right ventricle in the Fontan circulation: How does it work and why does it fail?.- Transcatheter pulmonary valve replacement: When should we pull the trigger? What do we hope to achieve?.- What should the echocardiographer tell me to plan tricuspid valve repair?.- Investigating the RV: What is the path going forward?.- Ventricular-vascular coupling in PAH: An engineer’s perspective is relevant to the clinician.- The RV in cardiac transplantation-How do we know if it’s going to cope and what do we do when it doesn’t?.- Does the RV really contract differently from the LV?.- How can computer models contribute to the clinician’s assessment of ventricular-ventricular interactions, ventricular-vascular interactions and RV failure?.- Can the RV support the failing LV.- Ebstein anomaly: Does echocardiographic assessment determine surgical repair?.- Arrhythmogenic right ventricular cardiomyopathy: Why does it happen and how do we make the diagnosis?.- Can surgeons preserve RV function in hypoplastic left heart syndrome?.- The RV in ccTGA: Why does it fail? Can we prevent it?.- Drugs?.- Assist devices.- News on the horizon.

Read more less

Book Synopsis

Read more less

Book Synopsis

Read more less

Book Synopsis1. Themeanrestingmembranepotentialofrattaste cells is - 36 mVunderadap- tation of the tongue to 41.4 mMNaCI and - 50mV under water adaptation. 2. The shapes ofreceptor potentials ofrattastecells inresponsetothe four basic tastestimuli(0.5MNaCI, 0.02 M Q-HCI, 0.01 MHCl, and0.5 M sucrose)are classified into three types, namely (1) a depolarization alone, (2) a depolariza- tion preceded by a transient hyperpolarization, and (3) a hyperpolarization alone. No regenerative spike potentials are evoked in rat taste cells by chemical stimuli. The amplitude of rat taste cell responses increases with increasing concentrationofthe taste stimulus. Mostofthe rat taste cells show a multiple sensitivity in that single cells respond to various combinations of the four basic taste stimuli with depolarizations or hyperpolarizations. 3. The rise and fall times of depolarizing responses to 0.5 M NaCI are much shorter than those of depolarizing responses to the other three stimuli. The fall time of depolarization evoked by 0.01 M HCI is the longest. The rise and fall times of all hyperpolarizing responses are shorter than those of all de- polarizing responses.Table of ContentsReceptor Potential in Rat Taste Cells.- Functional Properties of the Fish Olfactory System.- Homeostasis of Extracellular Fluid in Retinas of Invertebrates and Vertebrates.- Slowly Conducting Afferent Fibers from Deep Tissues: Neurobiological Properties and Central Nervous Actions.

Read more less

Book SynopsisDieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.Table of ContentsVergleichende Physiologie des Verdauungsapparates.- Die Nahrungsaufnahme bei Protozoen.- Die Verdauungsvorgänge bei Protozoen.- Einige vergleichend — physiologische Probleme der Verdauung bei Metazoen.- Über tierverdauende Pflanzen.- Normale und pathologische Physiologie des Verdauungsapparates der höheren Tiere, insbesondere des Menschen.- Chemie der Kohlehydrate.- Chemie der Fette.- Chemie der Eiweißkörper.- Mechanik der Nahrungsaufnahme und Nahrungsbeförderung.- Kaubewegungen und Bissenbildung.- Schlucken.- Pathologie des Schluckaktes.- Das Wiederkauen.- Die Magenbewegungen.- Der Brechakt.- Bewegungen des Darmes.- Die Defäkation.- Die Pathologie der Bewegungsvorgänge des Darmes (einschließlich der Obstipation und der Defäkationsstörungen) und der extrahepatischen Gallenwege.- Pharmakologie der Magen- und Darmbewegung (einschließlich Wirkungen der Hormone).- Die sekretorische Tätigkeit des Verdauungsapparates und die Funktion der Sekrete.- Funktionelle Anatomie und Histophysiologie der Verdauungsdrüsen.- Gewinnung reiner Sekrete der Verdauungsdrüsen.- Die sekretorische Tätigkeit der Verdauungsdrüsen.- Physikalische Eigenschaften und chemische Zusammensetzung der Verdauungssäfte unter normalen und abnormen Bedingungen.- Die Galle.- Fermente der Verdauung.- Die Wirkungen der Mikroorganismen im Verdauungstraktus.- Einfluß der Mikroorganismen auf die Vorgänge im Verdauungstraktus bei Herbivoren.- Über die Wechselbeziehungen zwischen Bakterienflora und den Verdauungsvorgängen beim Säugling.- Der Einfluß der Mikroorganismen auf die Vorgänge im Verdauungstraktus beim erwachsenen Menschen.- Pathologie der Verdauungsvorgänge.- Vergleichende pathologische Physiologie der Verdauung.- Pathologische Physiologie der Speicheldrüsen.- Pathologische Physiologie des Magensaftes und des Magenchemismus.- Pathologische Physiologie spezieller Krankheitsbilder.- Die Motilität und Sekretion des operierten Magens.- Pathologische Physiologie der Darmdrüsen.- Die äußere Sekretion des Pankreas unter pathologischen Bedingungen.- Gallenabsonderung und Gallenableitung.- Physiologie und Pathologie der Ernährungs- und Verdauungsvorgänge im frühen Kindesalter.- Physiologie und Pathologie der Ernährungs- und Verdauungsvorgänge im frühen Kindesalter.- Pharmakologie der Verdauungsdrüsen.- Pharmakologie der Verdauungsdrüsen.

Read more less

Book SynopsisWhy do we eat? Is it instinct, or some other impetus? Despite the necessity of food, anxieties about what and how to eat are widespread in our culture, and scientists and physicians continue to have shifting theories about the phenomenon of appetite and its causes and norms. In Appetite and Its Discontents, Elizabeth A. Williams charts the history of inquiry into appetite between 1750 and 1950, as scientific and medical concepts of appetite shifted alongside developments in physiology, natural history, psychology, and ethology. Williams argues that trust in appetite was undermined in the mid-eighteenth century, when researchers who investigated ingestion and digestion began claiming that science alone could say which ways of eating were healthy and which were not. Tracing nineteenth- and twentieth-century conflicts over the nature of appetite, Williams explores contemporary worries about eating through the lens of science and medicine to show us how appetite--once a matter of persoTrade Review"An exceptionally well-researched and detailed examination of appetite as an object of scientific and medical inquiry. Despite its strict focus on disciplinary debates, the gendered dimensions of appetite, particularly appetite disorders, is afforded attention throughout the book. Williams is careful to comment on the oppressive aspects of health as defined by scientific medicine and the potentially stigmatizing effects for those who deviate from normative frameworks. Graduate students and scholars interested in medicalization and healthism would benefit from reading this work. Fat studies scholars may also find this book of interest as Williams discusses the shifting conceptualization of 'obesity' and the drive toward thinness as a marker of health and well-being." * Food, Culture & Society *"Historian of Science Elizabeth Williams' wonderful new book Appetite and its Discontents: Science, Medicine and the Urge to Eat, 1750–1950 offers a fascinating, erudite, and illuminating narrative of the complex and contested relationship between appetite and scientific research, using changing scientific understandings of the appetite as a way for telling a distinct narrative of modernity. . . . the author pulls together scientists and practitioners from a remarkably wide array of disciplinary backgrounds, and from across Europe and the United States, to paint a story of the gradual transformation of appetite from a natural and ultimately positive aspect of the human condition to something both troublesome and misleading. In so doing, this book defines a key yet previously ignored topic of historical research, narrating shifts in scientific thinking that have profound implications for understanding contemporary society." * Journal of the History of Behavioral Sciences *"Deeply researched. . . . [Williams] has written what is undoubtedly the most comprehensive account of scientific and medical thinking since the Enlightenment about appetite. Her book is clearly and elegantly written, prodigiously researched and copiously referenced. It should be essential reading for historians of science, medicine and food." * Social History of Medicine *"Williams displays remarkable skill and encyclopedic knowledge in mining the output of scholars and practitioners in a wide range of fields for their thought and research on appetite. . . . Williams's book is carefully researched and that she has provided a great resource for anyone interested in expanding the history of appetite, or anyone interested in related fields such as the history of nutrition." * British Journal for the History of Science *"This fascinating book, magisterial and yet accessible, opens up broad questions about human life and culture through a careful focus on the meaning of appetite as a central, albeit often ill examined, 'natural' human drive. . . . Chapter by elegant chapter, the author elucidates contextual changes and deftly illustrates significant arguments through focused analyses covering Hippocrates and Aristotle through 20th-century psychiatry and psychoanalysis. The limitations set by the author for cogent analysis scarcely limit the connections that will reward readers, from central themes of gender and identities to relationships of appetite and larger systems of production and consumption, especially as she poses questions linking these historical processes to contemporary issues that permeate science, medicine, and Western culture more generally. . . . Rewarding and stimulating. . . . Recommended." * CHOICE *"Excellent. . . . A fascinating commentary on the current state of thinking as regards questions of appetite. . . . Appetite and its Discontents is a work to be celebrated not only by historians of medicine but by many others besides. . . . [Williams's] work represents something like an invitation to further research and discovery, encouraging expansion and curiosity." * European Journal for the History of Medicine and Health *"The narrative covers not only a broad swathe of time, but a huge range of disciplines impinging on the activity of eating. . . . The text is copiously referenced and well written in a solidly factual style. It will appeal to those interested in how something we all intuitively think we understand is actually very hard to pin down." * The Biologist (UK) *"A magisterial historical overview of research on the physiology and psychology of hunger. [Williams] makes clear how this long history continues to inform modern approaches to eating, and her book is essential reading for anyone interested in either historical or contemporary notions of appetite. . . . Williams sketches an unusually broad and inclusive arc of medical inquiry into an ephemeral sensation that precisely resisted the kind of disciplinary classification that its researchers frequently tried to bestow upon it. Readers will become intimately familiar with the plurality of investigators, methods, and texts that comprise appetite's fascinating history. . . . This book thoroughly impresses with its ambitions, scope, and execution. Williams has certainly achieved her primary goals. She vividly illustrates the convoluted historical processes by which appetite became an 'object' for scientists and physicians from numerous disciplines to investigate and ultimately control. Perhaps even more significantly, she suggests how an awareness of the many contested philosophies and approaches employed to understand the fickle sensation of hunger may help restore a freedom to modern appetites increasingly governed by scientific rigidity and expert advice." * New Mexico Historical Review *"What kind of phenomenon is appetite? Is it a natural thing or something driven by the availability of culinary luxury? Can be appetite be trusted as a guide to good eating or something that should be moralized or managed? . . . [Williams] records thinking that saw (and still see) appetite as a division or union between mind and body, questions what is normal and what is pathological, and asks is appetite a personal responsibility or something we can turn over (or blame) on dietetic authorities. Eventually and inevitably, she comes to examine attitudes toward obesity, with wide ranging theories including glandular, pathological fat tissue, maladies of nutrition, heredity, or habit." * CHoW Line *"Williams has written a fascinating and comprehensive history of the efforts of Western science and medicine to elucidate the functions and dysfunctions of appetite from the eighteenth century to the present. Her analysis of the myriad disciplinary and clinical studies on this elusive entity yields new and important insights into the evolution of methods and experiments on hunger and eating in medical and scientific practice against the background of the dramatic changes in the food supply over time. This deeply learned history has lessons galore for all us contemporary eaters." -- Robert A. Nye, Oregon State University"There is no equivalent scientific history of appetite available today. This book is the product of immense and extraordinarily wide-ranging research and it provides an important public service: it shows the narrow historical limits of current frames for thinking about appetite and obesity, and vividly brings alive other ways of thinking which once held sway. I strongly recommend it." -- Dana Simmons, University of California, Riverside"Appetite and Its Discontents interrogates the myriad ways in which scientists in the fields of natural history, physiology, medicine, psychology, and ethology conceptualized the phenomenon of appetite, differentiated it from hunger, and identified it as an important object of study. . . . a deeply researched monograph." * Isis *"Williams' study is an instructive and stimulating treasure trove of insights about appetite spanning more than two centuries... She reminds us of how fruitful it is to historicize food and nutrition alongside social debates on responsibility." * NTM Zeitschrift für Geschichte der Wissenschaften, Technik und Medizin (translated from German) *“A novel and compelling addition to a growing body of work focused on the complex historical relationship between humans and food, Appetite and Its Discontents is sprawling and well researched, presenting broad overviews as well as specific case studies that trace a well-supported historical lineage. The text is a welcome contribution to historiographies of science, medicine, and nutrition, and may be of particular interest to scholars and students in these fields as well as those interested in histories of psychology, science and technology studies, and epistemology at large.” * H-Net Reviews *"Since appetite is so key to organisms’ basic survival yet also firmly rooted in both body and mind, it continues to pose urgent but unanswerable questions for society—and Williams’s history of appetite shows us that we should not necessarily wait for scientists to answer them for us. In this book, she convincingly demonstrates, by carefully tracing the contours of important disciplinary debates, that there has never been clear scientific consensus around the ontology of appetite... Those interested in the narrow scientific or medical history of appetite will find Appetite and Its Discontents to be a detailed, overdue addition to the conversation." * Early American Literature *"It is one of the many merits of Williams’s book that it not only gives a clear account of the medical history of the study of appetite, but also raises so many more intriguing questions for further research." * Journal of Modern History *Table of ContentsList of Illustrations Introduction Part One Anxieties of Appetite: Created Needs in the Enlightenment, 1750–1800 Introduction to Part One 1 Why We Eat: The Ancient Legacy 2 “False or Defective” Appetite in the Medical Enlightenment 3 Human and Animal Appetite in Natural History and Physiology Part Two The Elusiveness of Appetite: Laboratory and Clinic, 1800–1850 Introduction to Part Two 4 Perils and Pleasures of Appetite at 1800: Xavier Bichat and Erasmus Darwin 5 The Physiology of Appetite to 1850 6 Extremes and Perplexities of Appetite in Clinical Medicine Part Three Intelligent or “Blind and Unconscious”? Appetite, 1850–1900 Introduction to Part Three 7 The Drive to Eat in Nutritional Physiology 8 The Psychology of Ingestion: Appetite in Physiological and Animal Psychology 9 Peripheral or Central? Disordered Eating in Clinical Medicine Part Four Appetite as a Scientific Object, 1900–1950 Introduction to Part Four 10 Psyche, Nerves, and Hormones in the Physiology of Ingestion 11 Appetite and the Nature-Nurture Divide: Eating Behavior in Psychology and Ethology 12 Somatic, Psychic, Psychosomatic: The Medicine of Troubled Appetite Epilogue: Appetite after 1950 Acknowledgments List of Abbreviations Notes Bibliography Index

Read more less

Book SynopsisTrade Review"An exceptionally well-researched and detailed examination of appetite as an object of scientific and medical inquiry. Despite its strict focus on disciplinary debates, the gendered dimensions of appetite, particularly appetite disorders, is afforded attention throughout the book. Williams is careful to comment on the oppressive aspects of health as defined by scientific medicine and the potentially stigmatizing effects for those who deviate from normative frameworks. Graduate students and scholars interested in medicalization and healthism would benefit from reading this work. Fat studies scholars may also find this book of interest as Williams discusses the shifting conceptualization of 'obesity' and the drive toward thinness as a marker of health and well-being." * Food, Culture & Society *"Historian of Science Elizabeth Williams' wonderful new book Appetite and its Discontents: Science, Medicine and the Urge to Eat, 1750–1950 offers a fascinating, erudite, and illuminating narrative of the complex and contested relationship between appetite and scientific research, using changing scientific understandings of the appetite as a way for telling a distinct narrative of modernity. . . . the author pulls together scientists and practitioners from a remarkably wide array of disciplinary backgrounds, and from across Europe and the United States, to paint a story of the gradual transformation of appetite from a natural and ultimately positive aspect of the human condition to something both troublesome and misleading. In so doing, this book defines a key yet previously ignored topic of historical research, narrating shifts in scientific thinking that have profound implications for understanding contemporary society." * Journal of the History of Behavioral Sciences *"Deeply researched. . . . [Williams] has written what is undoubtedly the most comprehensive account of scientific and medical thinking since the Enlightenment about appetite. Her book is clearly and elegantly written, prodigiously researched and copiously referenced. It should be essential reading for historians of science, medicine and food." * Social History of Medicine *"Williams displays remarkable skill and encyclopedic knowledge in mining the output of scholars and practitioners in a wide range of fields for their thought and research on appetite. . . . Williams's book is carefully researched and that she has provided a great resource for anyone interested in expanding the history of appetite, or anyone interested in related fields such as the history of nutrition." * British Journal for the History of Science *"This fascinating book, magisterial and yet accessible, opens up broad questions about human life and culture through a careful focus on the meaning of appetite as a central, albeit often ill examined, 'natural' human drive. . . . Chapter by elegant chapter, the author elucidates contextual changes and deftly illustrates significant arguments through focused analyses covering Hippocrates and Aristotle through 20th-century psychiatry and psychoanalysis. The limitations set by the author for cogent analysis scarcely limit the connections that will reward readers, from central themes of gender and identities to relationships of appetite and larger systems of production and consumption, especially as she poses questions linking these historical processes to contemporary issues that permeate science, medicine, and Western culture more generally. . . . Rewarding and stimulating. . . . Recommended." * CHOICE *"Excellent. . . . A fascinating commentary on the current state of thinking as regards questions of appetite. . . . Appetite and its Discontents is a work to be celebrated not only by historians of medicine but by many others besides. . . . [Williams's] work represents something like an invitation to further research and discovery, encouraging expansion and curiosity." * European Journal for the History of Medicine and Health *"The narrative covers not only a broad swathe of time, but a huge range of disciplines impinging on the activity of eating. . . . The text is copiously referenced and well written in a solidly factual style. It will appeal to those interested in how something we all intuitively think we understand is actually very hard to pin down." * The Biologist (UK) *"A magisterial historical overview of research on the physiology and psychology of hunger. [Williams] makes clear how this long history continues to inform modern approaches to eating, and her book is essential reading for anyone interested in either historical or contemporary notions of appetite. . . . Williams sketches an unusually broad and inclusive arc of medical inquiry into an ephemeral sensation that precisely resisted the kind of disciplinary classification that its researchers frequently tried to bestow upon it. Readers will become intimately familiar with the plurality of investigators, methods, and texts that comprise appetite's fascinating history. . . . This book thoroughly impresses with its ambitions, scope, and execution. Williams has certainly achieved her primary goals. She vividly illustrates the convoluted historical processes by which appetite became an 'object' for scientists and physicians from numerous disciplines to investigate and ultimately control. Perhaps even more significantly, she suggests how an awareness of the many contested philosophies and approaches employed to understand the fickle sensation of hunger may help restore a freedom to modern appetites increasingly governed by scientific rigidity and expert advice." * New Mexico Historical Review *"What kind of phenomenon is appetite? Is it a natural thing or something driven by the availability of culinary luxury? Can be appetite be trusted as a guide to good eating or something that should be moralized or managed? . . . [Williams] records thinking that saw (and still see) appetite as a division or union between mind and body, questions what is normal and what is pathological, and asks is appetite a personal responsibility or something we can turn over (or blame) on dietetic authorities. Eventually and inevitably, she comes to examine attitudes toward obesity, with wide ranging theories including glandular, pathological fat tissue, maladies of nutrition, heredity, or habit." * CHoW Line *"Williams has written a fascinating and comprehensive history of the efforts of Western science and medicine to elucidate the functions and dysfunctions of appetite from the eighteenth century to the present. Her analysis of the myriad disciplinary and clinical studies on this elusive entity yields new and important insights into the evolution of methods and experiments on hunger and eating in medical and scientific practice against the background of the dramatic changes in the food supply over time. This deeply learned history has lessons galore for all us contemporary eaters." -- Robert A. Nye, Oregon State University"There is no equivalent scientific history of appetite available today. This book is the product of immense and extraordinarily wide-ranging research and it provides an important public service: it shows the narrow historical limits of current frames for thinking about appetite and obesity, and vividly brings alive other ways of thinking which once held sway. I strongly recommend it." -- Dana Simmons, University of California, Riverside"Appetite and Its Discontents interrogates the myriad ways in which scientists in the fields of natural history, physiology, medicine, psychology, and ethology conceptualized the phenomenon of appetite, differentiated it from hunger, and identified it as an important object of study. . . . a deeply researched monograph." * Isis *"Williams' study is an instructive and stimulating treasure trove of insights about appetite spanning more than two centuries... She reminds us of how fruitful it is to historicize food and nutrition alongside social debates on responsibility." * NTM Zeitschrift für Geschichte der Wissenschaften, Technik und Medizin (translated from German) *“A novel and compelling addition to a growing body of work focused on the complex historical relationship between humans and food, Appetite and Its Discontents is sprawling and well researched, presenting broad overviews as well as specific case studies that trace a well-supported historical lineage. The text is a welcome contribution to historiographies of science, medicine, and nutrition, and may be of particular interest to scholars and students in these fields as well as those interested in histories of psychology, science and technology studies, and epistemology at large.” * H-Net Reviews *"Since appetite is so key to organisms’ basic survival yet also firmly rooted in both body and mind, it continues to pose urgent but unanswerable questions for society—and Williams’s history of appetite shows us that we should not necessarily wait for scientists to answer them for us. In this book, she convincingly demonstrates, by carefully tracing the contours of important disciplinary debates, that there has never been clear scientific consensus around the ontology of appetite... Those interested in the narrow scientific or medical history of appetite will find Appetite and Its Discontents to be a detailed, overdue addition to the conversation." * Early American Literature *"It is one of the many merits of Williams’s book that it not only gives a clear account of the medical history of the study of appetite, but also raises so many more intriguing questions for further research." * Journal of Modern History *Table of ContentsList of Illustrations Introduction Part One Anxieties of Appetite: Created Needs in the Enlightenment, 1750–1800 Introduction to Part One 1 Why We Eat: The Ancient Legacy 2 “False or Defective” Appetite in the Medical Enlightenment 3 Human and Animal Appetite in Natural History and Physiology Part Two The Elusiveness of Appetite: Laboratory and Clinic, 1800–1850 Introduction to Part Two 4 Perils and Pleasures of Appetite at 1800: Xavier Bichat and Erasmus Darwin 5 The Physiology of Appetite to 1850 6 Extremes and Perplexities of Appetite in Clinical Medicine Part Three Intelligent or “Blind and Unconscious”? Appetite, 1850–1900 Introduction to Part Three 7 The Drive to Eat in Nutritional Physiology 8 The Psychology of Ingestion: Appetite in Physiological and Animal Psychology 9 Peripheral or Central? Disordered Eating in Clinical Medicine Part Four Appetite as a Scientific Object, 1900–1950 Introduction to Part Four 10 Psyche, Nerves, and Hormones in the Physiology of Ingestion 11 Appetite and the Nature-Nurture Divide: Eating Behavior in Psychology and Ethology 12 Somatic, Psychic, Psychosomatic: The Medicine of Troubled Appetite Epilogue: Appetite after 1950 Acknowledgments List of Abbreviations Notes Bibliography Index

Read more less

Book SynopsisDistilling a vast amount of research in a style that is engaging, conversational, and even personal and witty, this book opens readers’ eyes to the complexity and significance of the humble knee.Trade ReviewHan Yu provides an engaging and accessible meditation on the human knee—its evolution, its structure, its function, its pathologies, its weaknesses, as well as its roles in society and fashion, the feminist and equality movements, and aggression. Who knew there were so many ways to view the human knee? -- Ian Tattersall, curator emeritus, American Museum of Natural HistoryWalking will never be the same. Kudos to Han Yu for exploring the functional development, frailties, and cultural impacts of this seemingly simple hinge joint. In a conversational tone, she bridges topics as disparate as women’s fashions, martial arts, therapeutic heat, and police tactics. Wonderful stories, personal anecdotes, and summaries of scientific investigations combine to provide the reader with openings for many stimulating dinnertime conversations. Who knew that flapper girls applied rouge to their knees to attract further attention? -- Roy A. Meals, MD, orthopedic surgeon and author of Bones, Inside and OutAs fun and entertaining as it is erudite and well-researched, this book is a very comprehensive look at an overlooked part of our anatomy, warts and all. -- Nathan H. Lents, author of Human Errors: A Panorama of Our Glitches, from Pointless Bones to Broken GenesIn this enlightening blend of science and cultural history, Yu (Mind Thief), an English professor at Kansas State University, considers the evolution and physiology of the human knee, as well as its role in fashion and customs. Yu excels at identifying colorful material on an ostensibly mundane subject, and lay readers will appreciate the accessible prose. This makes for an animated and wide-ranging exploration of an unassuming body part. * Publishers Weekly *Highly recommended. * Choice Reviews *Highly recommended. * American Library Association (ALA) *Table of Contents1. Knees Before the Brain2. Confused Anatomy3. Bare Knees, Dicey Power4. The Weaker Sex?5. To Kneel, or Not to Kneel6. Treatment, or Placebo7. The Hurtful Knee8. Race and Money9. Last WordsNotesBibliographyIndex

Read more less

Book SynopsisTrade ReviewBonnan combines wit and passion with the sensibilities of a talented instructor in this encyclopedic tour of the vertebrate skeleton . . . accessible even for those without a background in anatomy. * Publishers Weekly *No bones about it, a text like The Bare Bones was sorely needed in the popular literature of vertebrate paleontology. Matthew Bonnan's tome on the evolution, form, and function of the vertebrate skeleton may seem daunting in size, but it is written in an enjoyable and readable fashion that will absolutely delight all sorts of readers from expert to soon-to-be-expert. * Palaeontologia Electronica *The Bare Bones covers a lot of ground, much of it familiar, but it is a remarkably fun book to read. Bonnan avoids the most intimidating jargon of anatomy and phylogenetics, elucidating the necessary concepts through clear writing and clever application of nonbiological analogies. He is forthcoming about the simplifications and omissions that make the volume so readable, and his conversational style and wit make this an unintimidating yet highly informative book that would work wonderfully in college courses. * The Quarterly Review of Biology *Table of ContentsPrefaceAcknowledgmentsPart One: Setting the StageChapter 1. Introduction: How Vertebrates and Cars Are (and Are Not) SimilarChapter 2. Evolution to Deep Time, Pedigree to AnatomyPart Two: The Origin and Early Evolution of the Vertebrate ChassisChapter 3. Inferring the Basic Vertebrate ChassisChapter 4. Evolution of a Bony ChassisPart Three: The Evolution of the Jawed Vertebrate Chassis and Something FishyChapter 5. The Jawed Vertebrate Chassis: A PrimerChapter 6. Placoderms and Cartilaginous FishesChapter 7. The Fish-like Osteichthyes, Part 1Chapter 8. The Fish-like Osteichthyes, Part 2Part Four: The Vertebrate Chassis Moves to LandChapter 9. The Tetrapod Chassis: A PrimerChapter 10. The Tetrapod Chassis in TransitionChapter 11. The Amphibian ChassisChapter 12. The Amniote Chassis: A Primer and the Lead Up to True AmniotesPart Five: Deep Scaly I: Reptilian Chasses from Early Reptiles to Sea MonstersChapter 13. Lizards and the Tuatara as an IntroductionChapter 14. Early Reptiles and TurtlesChapter 15. Snakes and Sea DragonsPart Six: Deep Scaly II: The Archosaur Chassis, Those Ruling ReptilesChapter 16. The Archosaur Chassis, Part 1: Modern ArchosaursChapter 17. The Archosaur Chassis, Part 2: A Primer on Archosaur Posture and DiversityChapter 18. The Archosaur Chassis, Part 3: Pterosaurs, Dinosaurs, and the Origins of BirdsPart Seven: Overcome By Fur: The Mammalian ChassisChapter 19. The Mammalian Chassis: A PrimerChapter 20. The Evolution of the Mammal ChassisChapter 21. Brains, Milk, and the Modern Radiations of MammalsAppendix: The Cards of TimeReferences CitedIndex

Read more less

Book Synopsisto Biomechanics of Human Movement.- Fundamentals of Biomechanics and Qualitative Analysis.- Biological/Structural Bases.- Anatomical Description and Its Limitations.- Mechanics of the Musculoskeletal System.- Mechanical Bases.- Linear and Angular Kinematics.- Linear Kinetics.- Angular Kinetics.- Fluid Mechanics.- Applications of Biomechanics in Qualitative Analysis.- Applying Biomechanics in Physical Education.- Applying Biomechanics in Coaching.- Applying Biomechanics in Strength and Conditioning.- Applying Biomechanics in Sports Medicine and Rehabilitation.

Read more less

Book SynopsisBridging the gap between textbook diagrams and the complex reality of histological preparations, this magnificent atlas of human microanatomy is designed to help students understand the complex structures encountered when viewing microscopic sections of tissues. Instead of simply depicting an individual section, each drawing is a compilation of the key structures and features seen in many preparations from similar tissues or organs. Invaluable to students in a range of life science and medical disciplines including human and veterinary medicine, dentistry, mammalian biology, pharmacy, and nursing.Table of Contents1. Epithelial Tissue.- 2. Connective Tissue.- 3. Cartilage and Bone.- 4. Blood Cells and Hemopoietic Cells.- 5. Muscular Tissue.- 6. Nervous Tissue and Nervous System.- 7. Circulatory System.- 8. Lymphatic Organs.- 9. Respiratory System.- 10. Digestive System.- 11. Urinary System.- 12. Male Reproductive System.- 13. Female Reproductive System.- 14. Endocrine Organs.- 15. The Integument.- 16. The Eye.- 17. The Ear.- References.

Read more less

Book SynopsisAn engrossing examination of the science behind the little-known world of sleep.Trade Review"A lively overview of recent research into sleep." -- Maureen Corrigan - NPR's Fresh Air"A thoroughly enjoyable overview of a familiar yet remarkably foreign terrain." -- Abigail Zuger, MD - New York Times"The most diverting and consistently fascinating book on the topic ever... but you couldn’t find a more charming guide to what we do know than Dreamland." -- Laura Miller - Salon.com"A page-turner for the science-minded." -- Susannah Cahalan - New York Post"'Small science' at its best, illuminating aspects of human biology and behavior that have powerful repercussions in our private and social lives." -- Carol Tavris - Wall Street Journal"Randall’s wit and curiosity make him a comforting guide." -- Boston Globe"An accessible and well-researched guide to a fascinating subject." -- New Scientist"This fabulous book is likely to address any and all questions you might have about sleep.... There’s plenty of practical information, like how to overcome insomnia without drugs, how to combat snoring, how to encourage young children to get to sleep and, perhaps most useful, how to bet successfully on professional football games: our circadian rhythms favor West Coast teams over East Coast teams on Monday nights. This is one book that will not put you to sleep." -- Publishers Weekly, starred review"Randall emphasizes the too-often neglected common-sense realization that sleep is no void; rather, it is perhaps one-third of the puzzle to living well. The author also notes that sleep is not an undifferentiated continuum; the most restful sleep arrives in five stages of about 90 minutes each. A welcome study of an element of life that is often 'forgotten, overlooked, and postponed.'" -- Kirkus Reviews

Read more less

Book SynopsisA taboo-busting romp through the shame, stink and strange science of sweating.Trade Review"Love stinks! As do our immune systems, parenthood, and a host of other human functions. In this exuberant romp, a science journalist ponders the myths and marvels of perspiration, sniffing out why these glands are essential to our species. Everts employs original research and encounters with clinicians on the cutting edge, among them a Ph.D. who reverse-engineered his own odors. A glowing, revelatory account that belongs on the same shelf with works by Ed Yong and Carl Zimmer." -- 18 of the Best Books to Pick Up This July - Oprah Daily"[The Joy of Sweat is] an entertaining and illuminating guide to the necessity and virtues of perspiration... Everts is a crisp and lively writer." -- Jennifer Szalai - The New York Times Book Review"Everts’ book oozes with diverse information about sweat. Some of it busts unhelpful myth... But the ballast of The Joy of Sweat is Everts’ accounts of new biotechnologies that exploit perspiration." -- Peter Carty, the i newspaper - i newspaper"Most animals do not sweat to regulate their body temperature. Some evolutionary biologists even argue that perspiration helped humans to dominance, notes science journalist Sarah Everts in her well-researched, zesty study." -- Andrew Robinson reviews five of the week’s best science picks - Nature"In The Joy of Sweat, Sarah Everts offers a fascinating account of an involuntary bodily function that turns out to be as unique as a fingerprint." -- Irina Dumitrescu - Times Literary Supplement"Everts has charm and enthusiasm, writes breezily and, along the way, effectively debunks a number of enduring myths... this journey through one of the more arcane areas of human biology is fun, entertaining and full of interesting facts, whatever your levels of hidrosis." -- Simon Humphreys - The Daily Mail

Read more less

Book SynopsisA primer on brain functionality as it relates to therapeutic work.Trade Review"What makes this book stand out from others of its kind is the clinical dialogue interwoven with neurobiological commentary. This allows readers to be easily guided through complex neurobiological concepts, as well as clinical narrative. . . . [A]nyone interested in the application of neurobiological principles to psychotherapy will find this useful." -- Somatic Psychotherapy Today

Read more less

Book SynopsisWhat makes the heart beat faster or slower? How do tightrope walkers keep their balance? Why does spinning fast cause dizziness? Explore the mysteries and the workings of the human body through this fascinating collection of ideas, projects, and activities. Have fun while you learn about everything from the body''s basic building blocks to how the brain receives messages from other parts of the body. Make a model of a human cell that you can eat for dessert. Make a working model of a human lung from a soda bottle, a balloon, and a garbage bag. Through these and other activities, you''ll find out how your lungs supply air to your blood and your heart pumps blood throughout your body; how your body sees, hears, feels, smells, and tastes the world around it; how you lose and regain up to five pounds of skin every year; and much more. Most of the materials you need are already part of you; the rest you will easily find around the house or classroom. Every activity has been child tested andTable of ContentsBuilding Blocks. Breathrough. Brain Power. Controller. Balancing Act. Regulator. Quick Action. Overcoat. In Touch. Hairy, Scratchy Skin?. Seeing Is Believing. Sound Effects. Smellers. Tasters. Receivers. Tilt. In and Out. Travelers. Around and Around. The Pump. Food Processor. Support System. Pullers. And Then There Were Three. Pass It On. Glossary. Index.

Read more less

Book SynopsisAlthough normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the central nervous system. It has been shown that oestrogen acts as a neural growth factor with important influences on the survival, plasticity, regeneration, and aging of the mammalian forebrain.Trade Review"The text is an excellent summary of what is new on estrogens in the brain and will be of interest to neuroscience departments..." --Jnl of the Neurological Sciences, March 2001Table of ContentsChairman's Introduction (B. McEwen). Mechanism of Oestrogen Signalling with Particular Reference to the Role of ERß in the Central Nervous System (E. Treuter, et al.). Oestrogen Receptor Function at Classical and Alternative Response Elements (P. Kushner, et al.). GENERAL DISCUSSION I. Nuclear Receptor Versus Plasma Membrane Oestrogen Receptor (E. Levin). Novel Sites and Mechanisms of Oestrogen Action in the Brain (C. Toran-Allerand). Oestrogen Modulation of Noradrenaline Neurotransmission (A. Herbison, et al.). Oestrogen and the Cholinergic Hypothesis: Implications for Oestrogen Replacement Therapy in Postmenopausal Women (R. Gibbs). Ovarian Steroid Action in the Serotonin Neural System of Macaques (C. Bethea, et al.). Oestrogen Effects on Dopaminergic Function in Striatum (J. Becker). GENERAL DISCUSSION II. Oestrogen Effects in Olivo-Cerebellar and Hippocampal Circuits (S. Smith, et al.). Effects of Oestradiol on Hippocampal Circuitry (C. Woolley). Oestrogen and Cognitive Function Throughout the Female Lifespan (B. Sherwin). Neuroprotective Effects of Phenolic A Ring Oestrogens (P. Green, et al.). The Female Sex Hormone Oestrogen as Neuroprotectant: Activities at Various Levels (C. Behl, et al.). Neurohormonal Signalling Pathways and the Regulation of Alzheimer ß-Amyloid Metabolism (S. Gandy & S. Petanceska). Oestrogens and Dementia (V. Henderson). Indexes.

Read more less

Book SynopsisSkeletal Muscle Mechanics: From Mechanisms to Function summarises the variety of approaches used by todaya s scientist to understand muscle function and the mechanisms of contraction. This book contains research by leading scientists from numerous fields using many different scientific techniques.Table of ContentsPartial table of contents: MECHANISMS OF MUSCLE CONTRACTION. Considerations on the Mechanisms of Muscular Contraction (W. Herzog). Cross-bridge Action: Present Views, Prospects, and Unknowns (A. Huxley). THEORETICAL MODELLING OF MUSCLE AND MUSCLE CONTRACTION. Considerations on the Theoretical Modelling of Skeletal Muscle Contraction (W. Herzog). The Two-state Cross-bridge Model as a Link Between Molecular and Macroscopic Muscle Mechanics (G. Zahalak). Three-dimensional Geometric Model of Skeletal Muscle (R. Lemos, et al.). IN VIVO MUSCLE FUNCTION (HUMAN). Considerations on In Vivo Muscle Function (W. Herzog). In Vivo Mechanics of Maximum Isometric Muscle Contraction in Man: Implications for Modelling-based Estimates of Muscle Specific Tension (C. Maganaris & V. Baltzopoulos). Muscle Inhibition and Functional Deficiencies Associated with Knee Pathologies (E. Suter & W. Herzog). Effects of Ageing on Eccentric and Concentric Muscle Torque Production in Lower and Upper Limbs (A. Vandervoort, et al.). IN VIVO MUSCLE FUNCTION (ANIMAL). In Vivo Function and Functional Design in Steady Swimming Fish Muscle (S. Katz & R. Shadwick). Visco-Elastic Properties of Cardiac Trabeculae: Re-examination of Diastole (B. Stuyvers, et al.). Index.

Read more less

Book SynopsisThis book summarises the current state of the art of our understanding of the problem of non-communicable diseases and their primary prevention. It aims to increase international awareness of the global burden of non-communicable diseases and in particular to highlight the trends in developing countries; evaluates the impact of changes in diet, nutrition and lifestyle that predispose to chronic non-communicable diseases in modern societies; shares knowledge of the growing problems on non-communicable diseases and experiences related to its prevention between health professionals of developing and developed countries; identifies and prioritises major research issues and suggest strategies to deal with the global epidemic of chronic non-communicable diseases.Trade Review"This book represents a well organized and edited report of the Sixth Annual Public Health Forum.... Surely, [the Forum] and this book...borrowing a sentence from the preface, have 'given a significant contribution to the...acceleration of action that is required to counter and reverse...diet-related NCD.'" (European Journal of Public Health, Vol. 9, No. 1, 1999)Table of ContentsOverview of Diet-Related Non-Communicable Diseases. Prenatal Influences on Disease in Later Life. Cardiovascular Disease and Diabetes in Migrants - Interactions Between Nutritional Changes and Genetic Background. Inequalities in Diet and Health Dietary Fats and Non-Communicable Diseases. Diet and Large Bowel Cancer. Interactions Between Diet and endogenous Hormones: Possible Role in Breast Cancer Assessing the Net Effect of Alcohol Consumption on Mortality. The Public Health Impact of Globalisation of Food Trade Some Aspects of Norwegian Nutrition and Food Policy Symposium: The Burgeoning Global Burden of Obesity. Workshop Reports Diet, Lifestyle and Chronic Disease: Lessons From Contrasting Worlds. Where Do We Go From Here in Public Health? Index.

Read more less

Book SynopsisCurrent Toxicology Series Series Editors Diana Anderson BIBRA Toxicology International, Surrey, UK Michael D Waters Consultant, Chapel Hill, NC, USA Timothy C Marrs Department of Health, London, UK Nutrition and Chemical Toxicity Edited by Costas Ioannides, University of Surrey, Guildford, UK An enormous amount of research is currently devoted to evaluating the role of nutrition in the aetiology of major human diseases and to clarifying the underlying mechanisms. This resurgent interest reflects the realisation that carcinogens may be generated during the normal cooking of food and that they may play a role in human carcinogenesis. Moreover, during the last decade it has become apparent that naturally occurring chemicals in food, primarily of plant origin, can afford effective protection against human cancer and heart disease. As a result, the need for up-to-date information in this subject area has never been greater. Nutrition and Chemical Toxicity deals in depth with the various toxTrade Review"The book is a well structured reference source for nutritional toxicologists, with many clear and concise diagrams, and a comprehensive bibliography at the end of each chapter." (British Toxicology Society Newsletter)Table of ContentsToxicants in Food: Naturally Occurring (H. Mori, et al.). Toxicants in Food: Fungal Contaminants (J.-S. Wang, et al.). Toxicants in Food: Generated During Cooking (K. Skog & M. Jägerstad). Toxicants in Food: Food Allergens (G. Reese & S. Lehrer). Nutritional Modulation of Cytochromes P450 (C. Ioannides). Interactions between Drugs and Diet (J. Thomas, et al.). Glutathione, Sulphur Amino Acids and Chemical Detoxication (T. Bray, et al.). Modulation of the Carcinogenic Response by Caloric Restriction (A. Turturro, et al.). Lipotropes and Chemical Carcinogenesis (E. Farber & A. Ghoshal). Expression of Chemical Toxicity in Vitamin Deficiency and Supplementation (G. Williamson). Safety Evaluation of Vitamins and Minerals (J. Hathcock). Naturally Occurring Organosulphur Compounds as Potential Anticarcinogens (H. Mori & A. Nishikawa). Cancer Chemoprevention by Tea Polyphenols (N. Ahmad, et al.). Animal Diets in Safety Evaluation Studies (G. Rao & J. Knapka). Index.

Read more less

Book SynopsisThe seven distinguished contributors to this volume illuminate not only the history of the biological and medical sciences but also the relationship between institutes and ideas which characterized the explosion of scientific investigation, especially in Germany. Besides William Coleman and Frederic L. Holmes, they include Robert G. Frank, Jr., Timothy Lenoir, John E. Lesch, Kathryn M. Olesko, and Arlene M. Tuchman. Scientific investigation was not new to the nineteenth century, but it was during that period that it began to be carried out on a scale large enough to become crucial to the welfare of nations. Much remains to be learned about how the forms of organization characteristic of the modern investigative enterprise originated. This book explores such questions in relation to one of the dominant experimental sciences of the century, physiology. Each author shows, through the examination of a specific institute or a specific subject, that the interplay between research, pedagogy, personal vision, and state or public interests can be studied to particular advantage in localized settings.This title is part of UC Press's Voices Revived program, which commemorates University of California Press's mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1988.

Read more less

Book SynopsisExploring questions of how and why the quality of a person s voice influences our perceptions, Foundations of Voice Studies provides a comprehensive introduction to, and analysis of, the role that voice quality plays in our social lives.Trade Review“Foundations of Voice Studies has won the American Publishers Award for professional and Scholarly Excellence (PROSE Award) for best book of 2011 in the areas of Language and Linguistics. It has been praised as “a gem” by David Pisoni of Indiana University and “a remarkable book” by Stefanie Shattuck-Hufnagel of MIT. Even just its tables make this an invaluable book, worthy of a spot in every phonetician’s library.” (The Phonetician, 1 January 2011) Table of Contents1 Introduction. 2 Producing a Voice and Controlling Its Sound. 3 Neurological Foundations of Voice Production and Perception. 4 Physical Characteristics and the Voice: Can We Hear What a Speaker Looks Like? 5 Recognizing Speaker Identity From Voice: Theoretical and Ethological Perspectives and a Psychological Model. 6 The Brain Behind the Voice: Cerebral Models of Voice Production and Perception. 7 Identifying Unfamiliar Voices in Forensic Contexts. 8 Linguistic Uses of Voice Quality: How Voice Signals Linguistic and Pragmatic Aspects of Communication. 9 Perception of Emotion and Personality from Voice. 10 Miscellany: Voice in Law Enforcement, Media and Singing. References. Author Index. Subject Index.

Read more less

Book SynopsisWhether classified as regulators of inflammation, metabolism, or other functions, a distinctive set of molecules enables the body to convey information from one cell to another. Giamila Fantuzzi offers a primer on molecular mediators that coordinate complex bodily processes, and explores the consequences of their discovery for modern medicine.Trade ReviewFrom the way our brain thinks to how our body fights germs, the wonders of human life are fundamentally about how our cells and tissues interact. This book is a tour de force about how this communication happens. Examined with passion and insight, a wondrous and important story unfolds about how the human body really works above and beyond the level of individual genes and cells. -- Daniel M. Davis, author of The Compatibility GeneThe scholarship in the book is truly impressive. The interviews are revealing portraits of accomplished scientists. The writing style is lucid and purged of jargon so as to be intelligible to non-scientists. All in all this is a valuable and eminently readable record of the birth and development of a field that has had a dramatic impact on human health. -- Scott Durum, Center for Cancer Research, National Cancer InstituteReading this work will keep the reader current on a substantial number of recent, important studies on cell-to-cell information transfer. The reader will enjoy the personal essays and then want to read more about the scientific contributions. It is fascinating to find a work that is genuinely informative and also a joy to read. No matter the nature of the reader’s background, he or she will learn an immense amount of information from this book. -- F. W. Yow * Choice *

Read more less

Book SynopsisHuman Structure is an innovative introduction to human gross anatomy with a twofold approach to view the basics of anatomy from a broad scientific perspective and to explain the facts of form and function in terms and concepts that minimize the usual confusion and anxiety of beginning anatomy studies. Functional, comparative, and developmental anatomy are ingeniously woven into a single explanatory perspective, presenting human anatomy as an intelligible whole rather than as a heap of disconnected facts to be memorized. As a result, Human Structure is suitable not only for first-year medical students but also for undergraduates in premedical or biological science courses, for students in paramedical or college-level nursing programs, and indeed for anyone seeking a refresher course in human anatomy. The book begins with the generalized segmental organization characteristic of vertebrates and then examines the most obviously segmented parts of the human body: the bones, muscles, vesseTable of ContentsPreface Acknowledgments PART I: Vertebrate Anatomy and the Segmented Trunk 1. The Vertebrate Body 2. The Vertebral Column 3. The Spinal Cord and the Spinal Nerves 4. The Epaxial Muscles 5. The Body Wall PART II: The Thorax and its Viscera 6. The Development of the Mammalian Circulatory Pattern 7. The Heart and the Great Vessels 8. The Thorax PART III: The Abdomen and the Pelvis 9. The Abdominal Viscera 10. The Evolution and Development of the Urogenital Organs 11. The Pelvis and the Perineum PART IV: The Limbs 12. Fundamentals of Limb Anatomy 13. The Shoulder and the Arm 14. The Hand and the Forearm 15. The Hip and the Thigh 16. The Leg and the Foot 17. Upright Posture and Locomotion PART V: The Head and Neck 18. The Specializations of the Head 19. The Brain and the Skull 20. Nose, Eye, and Ear 21. The Pharyngeal Gut 22. The Cervical Segments Index

Read more less

Book SynopsisThe Hidden Mechanics of Exercise reveals the microworld of the body in motion, from motor proteins that produce force to enzymes that extract energy from food, and tackles questions athletes ask: What should we ingest before and during a race? How does a hard workout trigger changes in our muscles? Why does exercise make us feel good?Trade ReviewGillen’s enjoyable account emphasizes the molecules and protein structures that allow us to move, run, jump, control fuel use, and regulate adaptations to exercise training… Refreshingly, Gillen approaches the subject from the system down rather than the molecule up. Throughout the book, he emphasizes how tiny changes in protein structures scale up to produce whole-body movements… Gillen offers exercise enthusiasts wishing to understand the science behind their training an interesting read. The book also serves as an engaging primer for exercise-science students who want to begin to understand some of the underlying molecular mechanisms. The Hidden Mechanics of Exercise introduces concepts that make the step to the specialized textbook or research article easier. At the same time, researchers studying the behavior of the individual molecules may find Gillen’s account enlightening in regard to the functional implications of their work at the whole-body level. -- Stephen D. R. Harridge * Science *Anyone who has an interest in how the body and mind works in a sporting context will not only gain an insight and much knowledge, but also enjoy the way that the message is put across. * Athletics Weekly *To most of us, what happens deep inside our bodies when we exercise is a mysterious black box. This entertaining and illuminating book lucidly explains for nonspecialists the marvels of how molecules literally move a body. Gillen provides the ideal introduction to the physiology of exercise for anyone interested in how bodies work. -- Daniel E. Lieberman, author of The Story of the Human Body

Read more less

Book SynopsisTrade Review"I had never read the Hodgkin–Huxley papers until this book came my way. I am grateful that it did."---Brian Hayes, American Scientist"With this guide, Raman and Ferster have not only provided lecturers with the opportunity to includea review of the original Hodgkin–Huxley papers in their courses as a rare learning experience, but also have made accessible these historical documents to any interested neuroscientist of the post-Hodgkin–Huxley generations who otherwise would probably never haven taken—and enjoyed!—the intellectual ride of reading them. For this great service, the authors deserve our applause."---Günther K. H. Zupanc, Journal of Comparative Psychology A

Read more less

Book SynopsisTrade Review"I had never read the Hodgkin–Huxley papers until this book came my way. I am grateful that it did."---Brian Hayes, American Scientist"With this guide, Raman and Ferster have not only provided lecturers with the opportunity to includea review of the original Hodgkin–Huxley papers in their courses as a rare learning experience, but also have made accessible these historical documents to any interested neuroscientist of the post-Hodgkin–Huxley generations who otherwise would probably never haven taken—and enjoyed!—the intellectual ride of reading them. For this great service, the authors deserve our applause."---Günther K. H. Zupanc, Journal of Comparative Psychology A

Read more less

Book SynopsisAccurate analysis of blood gases is vital to give information on a patient's respiratory and circulation state as well as the adequacy of resuscitation. This text guides the reader through the basic principles and a new system of interpretation.Table of ContentsHow to take an arterial blood gas sample; the survival guide to understanding acid-base balance; too much alkali; the survival guide to understanding oxygenation; too little oxygenation; complex situations; special situations; putting it all together; self assessments.

Read more less

a huge range and FREE tracked UK delivery on ALL orders.

Read more less

Book SynopsisMaster the basics of anatomy and physiology in a flash! A multi-media, interactive approach makes learning fun and easy in any setting. This unique package of text, flash cards, and CD-ROM provides all of the elements you need to build a basic understanding of the structure and function of the human body.Table of Contents Anatomical Direction and Systems Cells and Tissues Integumentary System Skeletal System Blood and Lymphatic System Immunology Muscular System Nervous System Sensory System Digestive System Respiratory System Cardiovascular System Urinary System Endocrine System Reproductive System Appendices Review Exercise Answers Index of Key Terms Index of Pathology Terms

Read more less

Book SynopsisProvides the must-have knowledge you need of basic joint structure and muscle action and their normal and pathologic functions. The focus is on the science behind muscle function and movement and how groups of muscle together can contribute to function or dysfunction.Table of Contents Chapters/Online Modules I. Foundation Concepts 1. Principles of Kinesiology and Biomechanics 2. Structure and Function of Joints 3. Structure and Function of Muscles 4. Additional Biomechanical Principles II. The Vertebral Column 5. Structure and Function of the Spine 6. Structure and Ventilation Function of the Thorax 7. Structure and Function of the Temporomandibular Joint Appendix A: Attachments and Innervation of the Muscles and Structures of the Axial Skeleton III. The Upper Extremity 8. Structure and Function of the Shoulder Complex 9. Structure and Function of the Elbow Complex 10. Structure and Function of the Wrist and Hand Complex Appendix B. Attachments and Innervation of the Muscles and Structures of the Upper Exremity IV. The Lower Extremity 11. Structure and Function of the Hip Complex 12. Structure and Function of the Knee 13.Structure and Function of the Ankle and Foot Complex 14. The Kinesiology of Gait Appendix C. Attachments and Innervation of the Muscles and Structures of the Lower Extremity Glossary Index

Read more less

Book SynopsisBody system by system, the exercises and activities you'll find inside this text will help you to master the basics of anatomy and physiology. Complete the corresponding sections of the Workbook as you proceed from topic to topic in class.Table of Contents Chapter 1 Organization and General Plan of the Body Chapter 2 Some Basic Chemistry Chapter 3 Cells Chapter 4 Tissues and Membranes Chapter 5 The Integumentary System Chapter 6 The Skeletal System Chapter 7 The Muscular System Chapter 8 The Nervous System Chapter 9 The Senses Chapter 10 The Endocrine System Chapter 11 Blood Chapter 12 The Heart Chapter 13 The Vascular System Chapter 14 The Lymphatic System and Immunity Chapter 15 The Respiratory System Chapter 16 The Digestive System Chapter 17 Body Temperature and Metabolism Chapter 18 The Urinary System Chapter 19 Fluid-Electrolyte and Acid-Base Balance Chapter 20 The Reproductive Systems Chapter 21 Human Development and Genetics Chapter 22 An Introduction to Microbiology and Human Disease Appendices Glossary Index

Read more less

Book SynopsisTackle a tough subject in bite-sized pieces. A seemingly huge volume of information is organized into manageable sections to make complex concepts easy to understand and remember. You begin with an overview of the body, including its chemical and cellular structures, then progress to one-of-a-kind portrayals of each body system, grouped by function.Table of ContentsPart I Foundation of the BodyChapter 1 Orientation to the Human BodyChapter 2 Chemistry of LifeChapter 3 CellsChapter 4 Human MicrobiomePart II Covering, Support, and Movement of the BodyChapter 5 TissuesChapter 6 Integumentary SystemChapter 7 Bones & Bone TissueChapter 8 Skeletal SystemChapter 9 JointsChapter 10 Muscular SystemPart III Regulation and Integration of the BodyChapter 11 Nervous SystemChapter 12 Sense OrgansChapter 13 Endocrine SystemPart IV Maintenance of the BodyChapter 14 BloodChapter 15 HeartChapter 16 Vascular SystemChapter 17 Lymphatic & Immune SystemsChapter 18 Respiratory SystemChapter 19 Urinary SystemChapter 20 Fluid, Electrolyte, & Acid-Base BalanceChapter 21 Digestive SystemChapter 22 Nutrition & MetabolismPart V ContinuityChapter 23 Reproductive SystemsChapter 24 Pregnancy & Human DevelopmentChapter 25 HeredityAppendix Answers to Test Your Knowledge Questions

Read more less

Book Synopsis

Read more less

Book SynopsisOur Marvelous Bodies offers a unique perspective on the structure, function, and care of the major systems of the human body. Unlike other texts that use a strictly scientific approach, physiologist Gary F. Merrill relays medical facts alongside personal stories that help students relate to and apply the information.Trade Review"Merrill has written a concise yet thorough primier on the physiology of the major human body systems. Highly recommended." * CHOICE *"Using marvelous examples of everyday experience, Merrill effectively illustrates and explains many complex physiological processes. This blending of basic human biology with real-life stories greatly helps us to understand our own bodies—as patients, students, or as health care professionals." -- Richard A. Nyhof * professor of Biology, Calvin College *"Merrill's approach to science instruction is a unique one. I found it captivating." -- Byron Cryer * University of Texas Southwestern Medical School *Table of ContentsList of Figures List of Tables Preface1. The Foundation Structure and Function Homeostasis, Equilibrium, and the Steady State Physiological Gradients Physiological Reflexes Control Systems Analysis Feedback and Feedforward2. Understanding the Mammalian Nervous System What Are Neurons? What Is the Nervous System? Neuron Communication, Electrical and Chemical Transmission Different Neurotransmitters and Their Locations and Functions Discomfort, Pain, and the Nervous System Mental Activity, Cerebral Blood Flow, and Health of the Nervous System3. The Endocrine System and Physiological Communication Advances in Endocrinology Hormones, Proteins, and Peptides The Hypothalamic-Pituitary Axis Excesses and Deficiencies of GH and Health The Adrenal Gland and Growth The Thyroid Gland4. The Cardiovascular System and the Blood The Blood The Heart and Cardiac Cycle The Blood Vessels Lifestyle and Monitoring Cardiovascular Health Reactive Hyperemia and Blood Flow to Organs and Tissues5. Health and the Respiratory System Componenets of the Respiratory System Pulmonary Ventilation, or Lung Inflation and Deflation Respiration, Exchange, and Transport of Blood Gases Central and Peripheral Regulation of the Respiratory System Lungs and Balance of Acids and Bases Lifestyle and Care of the Lungs6. Kidneys and Renal Physiology Functional Morphology of the Kidneys Glomerular Filtration Rate and Urine Regulation of GFR and RPF REabsorption, Secretion, and the Formation of Urine Renal Health, Hydration, and Urination Diabetes and Sugar in the Urine7. The Gastrointestinal System Components of the Gastrointestinal (GI) or Enteric System Mechanics and Reflexes of the GI Tract Secretions of the GI Tract Digestion of Carbohydrates, Fats, and Proteins Health of the Oral Cavity and Vocalization Health of the GI Tract and Diet8. The Reproductive System Gametogenesis, Genetic, Gonadal, and Phenotypic Sex The Sexually Indifferent Embryonic Gonad Spermatogenesis and the Male Reproductive System Oogenesis, Folliculogenesis, and the Female Reproductive System Sexually Transmitted Diseases (STDs), Sexual Behavior, and Infertility9. The Immune System Cellular Defenses Chemotaxis, Margination, Diapedesis, and Phagocytosis Ports of Entry for Pathogens and the Reticuloendothelial System (RES) Immunity, Regenerative Medecine, and Stem Cells10. Muscle Function Muscle Diversification Excitation-Contraction Coupling in Muscle Cycling of Cross-Bridges and Shortening of Sarcomeres Muscle Levers, Hypertrophy, and Atrophy Muscle Diseases and Conditions Experimenting with Muscle11. Integrated Physiological Responses Hypovolemic Hypotension Baroreceptor Reflexes and Cardiac Output Vasomotor Responses and Blood Pressure Renal Response and the Renin-Angiotensin System Blood Flow and Its Distribution and Redistribution during Hypotension Long-Term Responses to Hypotension12. For the Record Blood Pressure and Your Health Blood Lipids and Physical Activity Blood Cells and Good Health Blood Sugar, Diabetes, and Metabolic Syndrome Glossary Notes and Suggested Reading Index

Read more less

Book SynopsisIn Our Intelligent Bodies, physiology professor Gary F. Merrill takes you on a guided tour through the human body and its marvelously sophisticated autonomic systems. Written in a fun, easy-to-comprehend style, it will give you a new appreciation for the smart decisions our bodies are making when our brains aren’t paying attention.Table of ContentsContents Preface 1 Intelligence and Problem Solving 2 Physiology of Light and Vision 3 Hearing and the Cochlea 4 Proprioception and Balance 5 Acid Base and pH Regulation 6 Cardiovascular and Hemodynamics 7 Respiration and Its Control 8 Kidneys and Body Water 9 Gut and Nutrient Flow

Read more less

Book SynopsisIn Our Intelligent Bodies, physiology professor Gary F. Merrill takes you on a guided tour through the human body and its marvelously sophisticated autonomic systems. Written in a fun, easy-to-comprehend style, it will give you a new appreciation for the smart decisions our bodies are making when our brains aren’t paying attention.Table of ContentsContents Preface 1 Intelligence and Problem Solving 2 Physiology of Light and Vision 3 Hearing and the Cochlea 4 Proprioception and Balance 5 Acid Base and pH Regulation 6 Cardiovascular and Hemodynamics 7 Respiration and Its Control 8 Kidneys and Body Water 9 Gut and Nutrient Flow

Read more less

Book SynopsisAs medical and surgical skills improve, innovative procedures can bring back patients who have travelled farther on the path to death than at any other time in history. Hagan and the contributors to this volume engage in evidence-based research on near-death experiences and include physicians who themselves have undergone a near-death experience.Trade Review“A subject currently the focus of intense public discussion, this book conveys a lot of important information in a very brief compass.”—Edward F. Kelly, University of Virginia, author of Beyond Physicalism: Toward Reconciliation of Science and Spirituality

Read more less

Book SynopsisThe use of stable isotopes in nutritional studies is now widespread, and the technique is becoming increasingly popular. Practical applications are numerous and include:calcium and iron absorption studiesstudies looking at the impacts of diet, physical activity, aging, and medical therapy and supplementation on nutrient metabolismthe measurement of energy cost of pregnancystudies on the causes of growth faltering in infantsinvestigations into childhood and adult obesity.This book is designed as a laboratory handbook of methods used to perform stable isotope studies in humans. It covers basic principles, dosage information, sample preparation procedures, analytical instrumentation, and necessary mathematical methods and provides the fundamentals to enable researchers to evaluate and establish stable isotope methods in their own laboratories.Table of Contents1: Introduction, S A Abrams and W W Wong 2: The measurement of protein kinetics with stable isotope tracers, F Jahoor, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center, Houston, Texas,USA 3: Stable isotope studies of macromineral metabolism: Calcium, magnesium and iron, S A Abrams 4: Evaluation of trace mineral status and bioavailability using stable isotopes (zinc, copper, selenium, molybdenum), N M Lowe, University of Central Lancashire, Preston, UK and C S Broome, University of Liverpool, UK 5: Energy utilization with doubly labelled water (2H218O), W W Wong 6: Body composition measurements with 2H218O isotope dilution, W W Wong 7: Stable isotopes and gas chromatoraphy - Mass spectrometry in studies of glucose and metabolism in children, A L Sunehag, and M W Haymond, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center, Houston, Texas, USA 8: Cholesterol and other lipid metabolism, R E Ostlund, Washington University School of Medicine, St Louis, Missouri, USA 9: Index

Read more less