Pathology Books
The University of Chicago Press Madness and Enterprise
Book SynopsisTrade Review“In this smart and sophisticated book, Bassiri shows us how an economic style of reasoning came to permeate psychiatry at the turn of the century. Not only were economic and psychiatric metaphors constantly entangled with one another but madness itself became central to economic rationalization. This book offers us a radically new perspective on the history of psychiatry. It also puts forth a fascinating philosophy of psychiatry which places irrationalism at the heart of modern capitalism.” -- Camille Robcis, Columbia University“For too long, we have accepted a contrast between madness and reason and all the more so between madness and economics. But Bassiri brilliantly demonstrates how our conceptions of madness and moral value are shot through with economic ideas, that in modern societies madness has had a fully economic rationality, that this economic rationality matters for social thought as much as for psychiatric treatments. In a historical epistemology that forces us to reread classics of modern psychology as much as relearn its story through half-forgotten intellectuals, he offers something truly original: a theory of suffering amid capitalist enterprise, and of the ways in which we can imagine a form of care unbound by a century and a half of transactional thinking.” -- Stefanos Geroulanos, New York University
£84.00
The University of Chicago Press Madness and Enterprise
Book SynopsisUncovers a powerful relationship between pathology and money: beginning in the nineteenth century, the severity of mental illness was measured against a patient's economic productivity. Madness and Enterprise reveals the economic norms embedded within psychiatric thinking about mental illness in the North Atlantic world. Over the course of the nineteenth century, various forms of madness were subjected to a style of psychiatric reasoning that was preoccupied with money. Psychiatrists across Western Europe and the United States attributed financial and even moral value to an array of pathological conditions, such that some mental disorders were seen as financial assets and others as economic liabilities. By turning to economic conduct and asking whether potential patients appeared capable of managing their financial affairs or even generating wealth, psychiatrists could often bypass diagnostic uncertainties about a person's mental state. Through an exploration of the intertwined hTrade Review“In this smart and sophisticated book, Bassiri shows us how an economic style of reasoning came to permeate psychiatry at the turn of the century. Not only were economic and psychiatric metaphors constantly entangled with one another but madness itself became central to economic rationalization. This book offers us a radically new perspective on the history of psychiatry. It also puts forth a fascinating philosophy of psychiatry which places irrationalism at the heart of modern capitalism.” -- Camille Robcis, Columbia University“For too long, we have accepted a contrast between madness and reason and all the more so between madness and economics. But Bassiri brilliantly demonstrates how our conceptions of madness and moral value are shot through with economic ideas, that in modern societies madness has had a fully economic rationality, that this economic rationality matters for social thought as much as for psychiatric treatments. In a historical epistemology that forces us to reread classics of modern psychology as much as relearn its story through half-forgotten intellectuals, he offers something truly original: a theory of suffering amid capitalist enterprise, and of the ways in which we can imagine a form of care unbound by a century and a half of transactional thinking.” -- Stefanos Geroulanos, New York University
£28.00
Springer-Verlag New York Inc. AJCC Cancer Staging Handbook
Book SynopsisGeneral Information on Cancer Staging and End-Results Reporting.- Purposes and Principles of Cancer Staging.- Cancer Survival Analysis.- Head and Neck.- Lip and Oral Cavity.- Pharynx.- Larynx.- Nasal Cavity and Paranasal Sinuses.- Major Salivary Glands.- Thyroid.- Mucosal Melanoma of the Head and Neck.- Digestive System.- Esophagus and Esophagogastric Junction.- Stomach.- Small Intestine.- Colon and Rectum.- Anus.- Gastrointestinal Stromal Tumor.- Neuroendocrine Tumors.- Liver.- Intrahepatic Bile Ducts.- Gallbladder.- Perihilar Bile Ducts.- Distal Bile Duct.- Ampulla of Vater.- Exocrine and Endocrine Pancreas.- Thorax.- Lung.- Pleural Mesothelioma.- Musculoskeletal Sites.- Bone.- Soft Tissue Sarcoma.- Skin.- Cutaneous Squamous Cell Carcinoma and Other Cutaneous Carcinomas.- Merkel Cell Carcinoma.- Melanoma of the Skin.- Breast.- Breast.- Gynecologic Sites.- Vulva.- Vagina.- Cervix Uteri.- Corpus Uteri.- Ovary and Primary Peritoneal Carcinoma.- Fallopian Tube.- Gestational Trophoblastic Tumors.- Genitourinary Sites.- Penis.- Prostate.- Testis.- Kidney.- Renal Pelvis and Ureter.- Urinary Bladder.- Urethra.- Adrenal.- Ophthalmic Sites.- Carcinoma of the Eyelid.- Carcinoma of the Conjunctiva.- Malignant Melanoma of the Conjunctiva.- Malignant Melanoma of the Uvea.- Retinoblastoma.- Carcinoma of the Lacrimal Gland.- Sarcoma of the Orbit.- Ocular Adnexal Lymphoma.- Central Nervous System.- Brain and Spinal Cord.- Lymphoid Neoplasms.- Lymphoid Neoplasms.Trade ReviewFrom the reviews of the seventh edition:“Provide a new organ-specific classification that oncologists and other professionals who manage patients with cancer need in order to accurately classify tumours for staging. … a ‘Bible’ for oncologists, pathologists and surgeons, being also useful for all health officers, including general physicians and students, who want to remain updated in oncology. … this is a book that has to be present in all diagnostic imaging departments, as a major support to produce information adequate to the new oncology algorithms.” (Vincenzo Cuccurullo and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 38, 2011)Table of ContentsGeneral Information on Cancer Staging and End-Results Reporting.- Purposes and Principles of Cancer Staging.- Cancer Survival Analysis.- Head and Neck.- Lip and Oral Cavity.- Pharynx.- Larynx.- Nasal Cavity and Paranasal Sinuses.- Major Salivary Glands.- Thyroid.- Mucosal Melanoma of the Head and Neck.- Digestive System.- Esophagus and Esophagogastric Junction.- Stomach.- Small Intestine.- Colon and Rectum.- Anus.- Gastrointestinal Stromal Tumor.- Neuroendocrine Tumors.- Liver.- Intrahepatic Bile Ducts.- Gallbladder.- Perihilar Bile Ducts.- Distal Bile Duct.- Ampulla of Vater.- Exocrine and Endocrine Pancreas.- Thorax.- Lung.- Pleural Mesothelioma.- Musculoskeletal Sites.- Bone.- Soft Tissue Sarcoma.- Skin.- Cutaneous Squamous Cell Carcinoma and Other Cutaneous Carcinomas.- Merkel Cell Carcinoma.- Melanoma of the Skin.- Breast.- Breast.- Gynecologic Sites.- Vulva.- Vagina.- Cervix Uteri.- Corpus Uteri.- Ovary and Primary Peritoneal Carcinoma.- Fallopian Tube.- Gestational Trophoblastic Tumors.- Genitourinary Sites.- Penis.- Prostate.- Testis.- Kidney.- Renal Pelvis and Ureter.- Urinary Bladder.- Urethra.- Adrenal.- Ophthalmic Sites.- Carcinoma of the Eyelid.- Carcinoma of the Conjunctiva.- Malignant Melanoma of the Conjunctiva.- Malignant Melanoma of the Uvea.- Retinoblastoma.- Carcinoma of the Lacrimal Gland.- Sarcoma of the Orbit.- Ocular Adnexal Lymphoma.- Central Nervous System.- Brain and Spinal Cord.- Lymphoid Neoplasms.- Lymphoid Neoplasms.
£49.49
John Wiley & Sons Inc The Biology of Cancer
Book SynopsisAdvances in research and the treatment of cancer mean that more patients and their carers are asking healthcare professionals about the latest treatments and how they may be of benefit. It is essential that staff working with cancer patients understand fully how these new treatments work in order to disseminate timely and appropriate information to patients. The application of biology to the delivery of cancer care is playing an ever-increasing role in the management of these diseases. The Biology of Cancer: Second Edition provides details of the most recent developments in cancer care and is divided into three sections: Understanding Cancer examines predisposing factors to developing cancer, diagnosis and its implications on the individual and society. The Science of Cancer a closer look at the cell, genetics, the immune system, tumour markers and monoclonal antibodies. Research and Treatment exploring translational oncology, applTrade Review"This edition would seem to be useful to a wide range of health staff working with patients affected by cancer … .Well referenced throughout and contains a helpful glossary." (Journal of Community Nursing, January 2009)Table of ContentsContributors. Preface. Acknowledgments. Introduction. Part 1. Understanding Cancer. Chapter 1. What is cancer?(Janice Gabriel). Chapter 2. Predisposing factors to developing cancer (Janice Gabriel). Chapter 3. Cancer: what does a diagnosis mean for an individual and what are the implications for society? (Janice Gabriel). Part II. The Science of Cancer. Chapter 4. The Cell (Louise Knight). Chapter 5. Cytotoxic Chemotherapy (Debbie Wright). Chapter 6. What are DNA and RNA? (Scott C. Edmunds). Chapter 7. Genetics and Cancer (Scott C. Edmunds). Chapter 8. The immune system (Helmout Modjtahedi & Ailsa Clarke). Chapter 9. Tumour Markers (F. Guy Gabriel). Chapter 10. Monoclonal antibodies (Helmout Modjtahedi). Part III. From Research to Treatment. Chapter 11. What is translational oncology research? (Elaine Lennan). Chapter 12. The application of research methodology to cancer research (Carmel Sheppard). Chapter 13. Research ethics relating to cancer (David Carpenter). Glossary. Reference. Index.
£47.45
John Wiley & Sons Inc Molecular Pathology in Drug Discovery and
Book SynopsisThe pharmaceutical industry is looking for new ways to better identify populations that will react positively to new drugs, and molecular pathology can fill that need.Trade Review“Molecular Pathology in Drug Discovery and Development is a well-written book that provides both an overview of how biomarkers may be developed and detailed explanations of how to measure and analyze said biomarkers.” (The Yale Journal of Biology and Medicine, March 2010)Table of ContentsPreface. Contributors. 1 MOLECULAR PATHOLOGY AND DRUG DEVELOPMENT (Franz Fogt and J. Suso Platero). 1.1. General Pathology. 1.2. General Aspects. 1.3. Molecular Pathology, the Molecular Way. 1.4. Application of Molecular Pathology. 1.5. Molecular Pathology in Drug Development. 1.6. Pharmaceutical Drug Development. References. 2 MOLECULAR PATHOLOGY IN ONCOLOGY TARGET AND DRUG DISCOVERY (Rolf-P. Ryseck, Ricardo Attar, Matthew V. Lorenzi, and Brent A. Rupnow). 2.1. Introduction. 2.2. History of Chemotherapy and Cancer Drug Discovery. 2.3. Target-Based Drug Discovery. 2.4. Utilization of Molecular Pathology in the Discovery of Novel Cancer Targets. 2.5. Hit Identifi cation and In Vitro Lead Optimization. 2.6. Implications for Molecular Pathology in Cancer Drug Development and Use. 2.7. Summary and Future Considerations. References. 3 MOLECULAR PATHOLOGY AND TRANSCRIPTIONAL PROFILING IN EARLY DRUG DEVELOPMENT (Cornelia Liedtke, Lajos Pusztai, and W. Fraser Symmans). 3.1. Introduction. 3.2. Biomarkers in Clinical Setting and in Early Drug Development. 3.3. Advantages of Biomarker Implementation. 3.4. Changing Paradigm in Clinical Drug and Biomarker Development. 3.5. Promises of Transcriptional Profiling. 3.6. Biomarker Development and Validation Using Microarray Analysis. 3.7. Neoadjuvant Chemotherapy as an Intriguing Model for Biomarker Development. 3.8. Transcriptional Profi ling for Identifi cation of Individual Genes as Biomarkers. 3.9. Transcriptional Profi ling for the Definition of Multigene Predictors Using .Transcriptional Profiling. 3.10. Novel Tools for Pathway Analysis. 3.11. Implementation of Biomarkers into the Clinical Setting. 3.12. Conclusion. References. 4 MOLECULAR PATHOLOGY IN NONCLINICAL SAFETY ASSESSMENT (Richard A. Westhouse). 4.1. Introduction. 4.2. Drug Development. 4.3. Drug Discovery. 4.4. Biopharmaceuticals. 4.5. Summary. References. 5 TOXICOGENOMICS IN DRUG DEVELOPMENT (Wayne R. Buck and Eric A. G. Blomme). 5.1. Introduction. 5.2. Brief Overview of Large-Scale Gene Expression Technologies. 5.3. Analysis of Microarray Data. 5.4. Application of Toxicogenomics in Drug Development. 5.5. Considerations for Toxicogenomic Study Design. 5.6. Overview of Major Regulatory Developments Related to Use of Toxicogenomics in Drug Discovery and Development. 5.7. Summary. References. 6 MOLECULAR PATHOLOGY AS A WAY TO FIND THE RIGHT DOSE FOR A DRUG (F. Rojo, A. Rovira, S. Serrano, and J. Albanell). 6.1. Introduction. 6.2. Anti-EGFR-Targeted Therapies: The Pharmacodynamic Experience. 6.3. Molecular Pathology with Small Molecules Gefitinib and Erlotinib. 6.4. Molecular Pathology with Cetuximab and Other Monoclonal Antibodies to EGFR. 6.5. Proteasome Inhibitors: Pharmacodynamics on Blood Samples. 6.6. Pharmacodynamics with Rapamycin Analogs. 6.7. Second Generation of Targeted Therapies: Multitarget Agents. 6.8. Conclusions and Perspectives: Phase 0 Clinical Trials. References. 7 MOLECULAR PATHOLOGY IN LIFE-CYCLE MANAGEMENT IN DRUG DEVELOPMENT (Martha Quezado, Carlos A. Torres-Cabal, and David Berman). 7.1. Introduction. 7.2. Molecular Pathology Techniques. 7.3. Practical Applications of Molecular Pathology Biomarkers. 7.4. Conclusion. References. 8 MOLECULAR PATHOLOGY AND MOLECULAR THERAPY (Hewei Li). 8.1. Introduction. 8.2. Molecular Therapy Strategies. 8.3. Molecular Therapy Clinical Trials. References. 9 MOLECULAR PATHOLOGY: IMMUNOHISTOCHEMISTRY ASSAYS IN DRUG DEVELOPMENT PERFORMED BY A CONTRACT RESEARCH LABORATORY (Frank Lynch and Steve Bernstein). 9.1. Immunohistochemistry Is the Technique of Microscopic Visualization of Target Proteins in Tissue Sections Using Specific Antibodies. 9.2. Basics of the IHC Assay. 9.3. Immunohistochemistry Assay Development. 9.4. Sending a Study to a Contract Laboratory vs. Running In-house. 9.5. Choosing and Working with an Outside Laboratory— Keys for a Succe.ssful Relationship—What to Do before a Slide Is Stained. 9.6. Running and Managing Outsourced Clinical Studies 9.7. Applications of IHC in Drug Discovery and Development Process. 9.8. Conclusion. References. 10 QUANTIFICATION OF MOLECULAR PATHOLOGY: COLORIMETRIC IMMUNOHISTOCHEMISTRY (Raphael Marcelpoil). 10.1. Introduction. 10.2. Imaging Devices and Systems. 10.3. Quantifi cation: Introduction to Colorimetric Image Analysis. 10.4. Measuring Colorimetric Information. 10.5. Chromogen Separation. 10.6. Measuring Information. 10.7. Conclusion. References. 11 AQUA® TECHNOLOGY AND MOLECULAR PATHOLOGY (Mark Gustavson, Marisa Dolled-Filhart, Jason Christiansen, Robert Pinard, and David Rimm). 11.1. Introduction. 11.2. AQUA Technology—How It Works. 11.3. Standardization. 11.4. Quantification. 11.5. Localization. 11.6. Multiparametric Analysis. 11.7. Application of AQUA Technology to Drug Discovery and Companion Diagnostics. 11.8. Summary and Conclusions. References. Index.
£116.96
John Wiley & Sons Inc Cardiovascular Effects of Inhaled Ultrafine and
Book SynopsisThis book assists scientists, toxicologists, clinicians, and public health regulators to understand the complex issues that determine the impact of air pollution on the cardiovascular system.Trade Review"It is timely and detailed in its account of complex issues attending air pollution related to the cardiovascular and cardiopulmonary systems. . . This book could well be the most important occupational and environmental health book I have ever read." (Doody's, 16 September 2011) Table of ContentsFOREWORD. PREFACE. THE EDITORS. CONTRIBUTORS. PART I. ISSUE FRAMING. CHAPTER 1 OVERVIEW (Flemming R. Cassee and Morton Lippmann). CHAPTER 2 ACUTE EFFECTS OF PARTICULATE MATTER ON THE RISK OF MYOCARDIAL INFARCTION (Krishnan Bhaskaran, Shakoor Hajat, and Liam Smeeth). CHAPTER 3 CHRONIC EFFECTS OF AIR POLLUTION ON CARDIOVASCULAR HEALTH (Ranjini M. Krishnan, Joel Kaufman, and Gerard Hoek). PART II. EXPOSURE. CHAPTER 4 PARTICLE CHARACTERIZATION (Thomas A.J. Kuhlbusch and Christof Asbach). CHAPTER 5 EXPOSURE ASSESSMENT FOR AMBIENT ULTRAFINE PARTICLES (Timo Lanki, Josef Cyrys, H.-Erich Wichmann, and Jeroen de Hartog). CHAPTER 6 FROM EXPOSURE TO DOSE (Werner Hofmann and Bahman Asgharian). CHAPTER 7 TRANSLOCATION OF INHALED NANOPARTICLES (Wolfgang G. Kreyling, Winfried Möller, Otmar Schmid, Manuela Semmler-Behnke, and Günter Oberdörster). CHAPTER 8 ROLE OF CHEMICAL COMPOSITION IN DETERMINING THE CARDIOVASCULAR EFFECTS OF PARTICLES (Andrew J. Ghio and Yuh-Chin T. Huang). PART III. METHODOLOGY. CHAPTER 9 IN VITRO STUDIES (Per E. Schwarze and Gerrit M. Alink). CHAPTER 10 EXPERIMENTAL STUDIES IN ANIMALS (Urmila P. Kodavanti, Lung-Chi Chen, and Daniel L. Costa). CHAPTER 11 HUMAN EXPOSURE STUDIES (Jeremy P. Langrish, Mark W. Frampton, and Anders Blomberg). CHAPTER 12 PANEL STUDIES (Joel Schwartz). PART IV. PARTICLES AND CARDIOVASCULAR DISEASE: MECHANISMS. A. ATHEROGENESIS. CHAPTER 13 PARTICULATES AND OXIDATIVE STRESS (Steffen Loft, Roel P.F. Schins, and Peter Møller). CHAPTER 14 ROLE OF INFLAMMATION IN THE ATHEROGENIC EFFECTS OF PARTICULATE MATTER (Thomas Sandström and David Newby). CHAPTER 15 INHALED PARTICLES, POSTPRANDIAL LIPIDS, AND THEIR POSSIBLE CONTRIBUTION TO ATHEROGENESIS: THE TROJAN HORSE HYPOTHESIS (Carlijne Hassing, Maarten J.M. Cramer, and Marcel Th.B. Twickler). CHAPTER 16 INHALED PARTICULATE MATTER AND ATHEROSCLEROSIS IN HUMANS (Barbara Hoffmann and Nino Künzli). CHAPTER 17 EFFECTS OF NANOPARTICLES ON THE PULMONARY VASCULATURE (Laurel E. Plummer, Kent E. Pinkerton, Amy K. Madl, and Dennis W. Wilson). CHAPTER 18 PARTICULATE MATTER, HYPERTENSION, AND THE METABOLIC SYNDROME (Robert D. Brook and Sanjay Rajagopalan). CHAPTER 19 PARTICLES AND THE VASCULAR ENDOTHELIUM (Nicholas L. Mills and Mark R. Miller). PART IV. PARTICLES AND CARDIOVASCULAR DISEASE: MECHANISMS. B. VASCULAR DYSFUNCTION. PART IV. PARTICLES AND CARDIOVASCULAR DISEASE: MECHANISMS. C. THROMBOSIS. CHAPTER 20 PARTICLES, COAGULATION, AND THROMBOSIS (Evren Kilinç, Goran Rudež, Henri M.H. Spronk, Abderrahim Nemmar, Moniek P.M. de Maat, Hugo ten Cate and Marc F. Hoylaerts). CHAPTER 21 PARTICLES AND THE PATHOGENESIS OF ATHEROTHROMBOSIS (Qinghua Sun and Xiaohua Xu). PART IV. PARTICLES AND CARDIOVASCULAR DISEASE: MECHANISMS. D. ARRHYTHMIA. CHAPTER 22 PARTICLES AND THE AUTONOMIC NERVOUS SYSTEM (Swapna Upadhyay, Alison Elder, Wayne E. Cascio, and Holger Schulz). CHAPTER 23 AIR POLLUTION AND ARRHYTHMIA (Helen C. Routledge and Jonathan N. Townend). PART V. ENVIRONMENTAL AND PUBLIC HEALTH POLICY. CHAPTER 24 RISK ASSESSMENT (Robert L. Maynard and Jon G. Ayres). CHAPTER 25 ENVIRONMENTAL REGULATION OF PARTICULATE MATTER (Richard Damberg, Klaas Krijgsheld, May Ajero, and Sophie Punte). CHAPTER 26 FROM AMBIENT ULTRAFINE PARTICLES TO NANOTECHNOLOGY AND NANOTOXICOLOGY (Ken Donaldson and David B. Warheit). INDEX.
£142.16
John Wiley & Sons Inc Endotoxin and Sepsis
Book SynopsisProgress in Clinical and Biological Research, Volume 397 ENDOTOXIN AND SEPSIS Molecular Mechanisms of Pathogenesis, Host Resistance, and Therapy Proceedings of the Fourth Conference of the International EndotoxinSociety Held in Nagoya, Japan, October 23-27, 1996 Jack Levin, Matthew Pollack, Takashi Yokochi, and Masayasu Nakano,Editors Recent breakthroughs in our understanding of the molecular biologyof the human immune response have lead to important advances in therecognition and treatment of sepsis. Endotoxin and Sepsis:Molecular Mechanisms of Pathogenesis, Host Resistance, and Therapycompiles the latest basic and clinical research on many aspects ofsepsis, including sepsis/SIRS. It provides researchers andclinicians with an up-to-date overview of the critical data andconcepts in this rapidly progressing field of inquiry. Featuring contributions by researchers and clinicians from aroundthe world, this book presents papers coveringTable of ContentsEnzymes of Lipid A Biosynthesis: Target for the Design of New Antibiotics (C. Raetz). Biosynthesis of Escherichia coli 09 Polysaccharide and its Evolution (N. Kido). Core Structure, of Enterobacterial Lipopolysaccharides (O. Holst, et al.). Unique Structural and Biological Features of Helicobacter pylori Lipopolysaccharides (A. Moran & G. Aspinall). What We Know and Don't Know about the Chemical and Physical Structure of Lipopolysaccharides in Relation to Biological Activity (S. Müller-Loennies, et al.). Roles for LBP and Soluble Cd14 in Cellular Uptake of LPS (R. Tapping, et al.). Structure-Function Analysis of Soluble and Membrane-Bound CD14 (T. Kirkland & S. Viriyakosol). Roles of CD14 in LPS Signaling and Scavenging: Analysis of CD14-Transgenic and Non-Transgenic Mice and Rats in Response to LPS (S. Yamamoto, et al.). The Role of Scavenger Receptors in LPS-Induced Macrophage Activation (T. Kirikae, et al.). The CD11/CD18 Integrins: Characterization of Three Novel LPS Signaling Receptors (R. Ingalls, et al.). The Role of Tyrosine Kinases and MAP Kinases in LPS-Induced Signaling (A. DeFranco, et al.). CD14 Dependent and Independent Signaling Pathways in Murine Macrophages from Normal and CD14 "Knockout" (CD14KO) Mice Stimulated with LPS or Taxol (S. Vogel, et al.). ADP-Ribosylation: Role in LPS-Induced Phosphorylation of Two Cytosolic Proteins (p36/38) in Monocytes (S. Hauschildt, et al.). CD14 Dependent Mechanisms of Cell Activation (J. Han, et al.). Cytokine Regulation of Inducible Nitric Oxide Synthase in Vascular Smooth Muscle Cells (J. Cohen, et al.N). Detoxification of Lipopolysaccharide by Lysozyme (N. Ohno, et al.). Role of Hepatocytes in the Clearance of Lipopolysaccharide and its Clinical Significance (K. Tanikawa, et al.). Antibiotic-Mediated Release of Endotoxin and the Pathogenesis of Gram-Negative Sepsis (D. Morrison). Molecular Mechanisms Responsible for Endotoxin Tolerance (B. Yoza, et al.N). Endotoxin Tolerance Alters Macrophage Membrane Regulatory G Proteins (M. Makhlouf, et al.). Lipopolysaccharide (LPS) Antibodies Regulate Cellular Uptake of LPS and LPS Induced Proinflammatory Responses (C. Ohl & M. Pollack). Apoptotic Cell Death in Response to LPS (T. Yokochi, et al.). Stimulation of Human T Lymphocytes by Lipopolysaccharide (LPS) in the Presence of Autologous and Heterologous Monocytes (T. Mattern, et al.). Role of CD14 in Infection: Studies in CD14-Deficient Mice (A. Haziot, et al.). Reconciling the Concepts of Endotoxin Sensitization and Tolerance (M. Freudenberg, et al.). Production of Nontoxic Lipid A by Chemical Modification and its Antagonistic Effect on LPS Activity (K. Tanamoto). The Protective Effect of Prostaglandin E1 on Endotoxin-Induced Hepatocyte Injury (H. Shimada, et al.). Natural and Synthetic LPS and Lipid A Analogs or Partial Structures that Antagonize or Induce Tolerance to LPS (N. Qureshi, et al.). The Molecular Basis for Therapeutic Concepts Utilizing CD14 (F. Stelter, et al.). Natural and Synthetic Polypeptides that Recoggnize the Conserved Lipid A Binding Site of Lipoplysaccharides (M. Porro, et al.). Prevention of Endotoxin Shock through Targeting Leukocytes Adhesion Molecules (H. Higashi, et al.). Suppression of TNF and other Proinflammatory Cytokines by the Tetravalent Guanylhydrazone CNI-1493 (K. Tracey). Interaction of Lipopolysaccharide with a Mammalian Lyso-phosphatidate Acyltransferase (LPAAT) Tranfected into E. coli, and Effect of Lisofylline on LPAAT Transfected into Mammalian Cells (S. Bursten). Role of Nitric Oxide and Reactive Oxygen Species in Endotoxin Shock (T. Yoshikawa, et al.). The Role of Interleukin 6 in Endotoxin-Induced Inflammatory Responses (T. van der Poll & S. van Deventer). The Pathogenic Role of LBP in Gram-Negative Sepsis and Septic Shock (D. Heumann, et al.). Index.
£999.99
John Wiley & Sons Inc Biomolecular Free Radical Toxicity
Book SynopsisBiomolecular injury is damage inflicted by a reactive molecule on a biological molecule. This work presents up-to-date and wide-ranging information in a user-friendly format for research scientists specializing in food and nutrition-based toxicology.Table of ContentsMACROMOLECULAR MECHANISMS OF INJURY AND THE ROLE OF ANTIOXIDANTS. Membrane Lipid and Lipoprotein Injury: Prevention by Antioxidants (H. Wiseman & T. Ridgway). DNA Injury: Prevention by Antioxidants (R. Hambly). Protein Injury: Prevention by Antioxidants (B. Evans & J. Woodward). GENE EXPRESSION AND CELL MEDIATED MECHANISMS OF TOXICITY EXPRESSION. Xenobiotic Metabolism and Bioactivation by Cytochromes P-450 (C. Ioannides). Apoptosis Triggered by Free Radicals: Role in Human Diseases (G. Kass, et al.). HUMAN AND ENVIRONMENTAL HEALTH EFFECTS. Dietary Phytoestrogens, Oestrogens and Tamoxifen: Mechanisms of Action in Modulation of Breast Cancer Risk and Prevention of Heart Disease (H. Wiseman). Strategies for the Removal of Ecotoxicants: Environmental Oestrogens and Oestrogen-Mimics (T. Ridgway & H. Wiseman). Index.
£228.56
John Wiley & Sons Inc Foundations of Medical Imaging
Book SynopsisThis handbook of medical imaging relates all concepts to electronic engineering. It provides an understanding of applied physics and its principles in order to allow for the design, transmittal and interpretation of electronic imaging signals and systems.Table of ContentsBASICS FOR MEDICAL IMAGING. Mathematical Preliminaries for Image Processing. Image Reconstruction from Projections in Two Dimensions. Image Reconstruction from Projections--True Three-Dimensions andOther Related Techniques. IMAGING WITH IONIZING RADIATION. Radiation Physics and Detectors. X-Ray Computerized Tomography. Nuclear Tomographic Imaging--Single Photon Emission ComputedTomography. Tomographic Nuclear Medical Imaging--Positron EmissionTomography. MAGNETIC RESONANCE IMAGING. Nuclear Magnetic Resonance Physics and Instrumentation. Magnetic Resonance Imaging: Mathematics and Algorithms. Magnetic Resonance Imaging: Methods and Techniques. Flow and Flow-Related Magnetic Resonance Imaging. Chemical-Shift and Spectroscopic Imaging. ULTRASOUND AND ULTRASONIC IMAGING. Ultrasound Physics. Ultrasonic Imaging. BIOMAGNETIC IMAGING. Neuromagnetic Imaging. Index.
£184.46
MP-FAD F.A. Davis Pathology for the Physical Therapist Assistant
Book SynopsisMeets the needs of PTA students for usable, understandable pathology related to clinical application. Extensively illustrated, this book allows students to more easily comprehend and maintain interest in otherwise complicated pathological processes.Table of Contents 1. Inflammation and Healing 2. Immunopathology, Neoplasia and Chromosome Abnormalities 3. Cardiovascular Pathologies 4. Respiratory Diseases 5. Degenerative Joint Diseases and Bone Pathologies 6. Rheumatoid Arthritis and Related Conditions 7. Neurological Disorders 8. Burns and Skin Conditions 9. Endocrine, Metabolic, and Nutritional Disorders 10. Infectious Diseases 11. Female and Male Reproductive System Conditions 12. Diseases of the Digestive Tract and Urinary System 13. Intensive Care 14. The Geriatric Patient
£63.90
Springer-Verlag New York Inc. Sepsis
Book SynopsisThis detailed volume presents a variety of animal models that are commonly used to study sepsis and some key procedures to measure specific disease outcomes.Table of Contents1. Cecal Ligation and Puncture Susanne Drechsler and Marcin Osuchowski 2. Colon Ascendens Stent Peritonitis (CASP) Anna Herminghaus and Olaf Picker 3. Induction of Sepsis via Fibrin Clot Implantation Sailaja Ghanta, Min-Young Kwon, and Mark A. Perrella 4. Cecal Slurry Injection in Neonatal and Adult Mice Jaimar C. Rincon, Philip A. Efron, Lyle L. Moldawer, and Shawn D. Larson 5. Injection of Escherichia coli to Induce Sepsis Xian-Hui He, Dong-Yun Ouyang, and Li-Hui Xu 6. A Mouse Model of Pseudomonas aeruginosa Pneumonia Brian W. LeBlanc and Craig T. Lefort 7. A Mouse Model of Candidiasis Pilar Fajardo, Ana Cuenda, and Juan José Sanz-Ezquerro 8. Francisella tularensis Infection of Mice as a Model of Sepsis Charles T. Spencer, Mireya G. Ramos Muniz, Nicole R. Setzu, and Michelle A. Sanchez 9. A Mouse Model of Necrotizing Enterocolitis Belgacem Mihi, Wyatt E. Lanik, Qingqing Gong, and Misty Good 10. A Murine Model of Full-Thickness Scald Burn Injury with Subsequent Wound and Systemic Bacterial Infection Antonio Hernandez, Naeem K. Patil, and Julia K. Bohannon 11. Mouse Intensive Care Unit (MICU) Tamara Merz, Sandra Kress, Michael Gröger, Peter Radermacher, and Oscar McCook 12. Creation of BLT Humanized Mice for Sepsis Studies Erica L. Heipertz and Wendy E. Walker 13. Scoring Sepsis Severity in Mice Tina S. Mele 14. Identification of ILC2 in the Lung Using Flow Cytometry Hui Xu and Meihong Deng 15. Measurement of Intestinal Permeability During Sepsis Takehiko Oami and Craig M. Coopersmith 16. Sepsis Biomarkers Yachana Kataria and Daniel Remick 17. Detection of Blood Cell Surface Biomarkers in Septic Mice Dinesh G. Goswami and Wendy E. Walker 18. Microfluidic Chips for Sepsis Diagnosis Yun Zhou, Yijia Yang, and Dimitri Pappas 19. Analgesia and Humane Endpoints for Rodents in Sepsis Research Christine A. Boehm and Jean A. Nemzek 20. Agent-Based Modeling of Systemic Inflammation: A Pathway towards Controlling Sepsis Gary An and Chase Cockrell
£98.99
John Wiley and Sons Ltd The Cutaneous Lymphoid Proliferations A
Book SynopsisA masterful and thorough revision of the only single-source, authoritative reference on cutaneous lymphoproliferative disease.Table of ContentsAcknowledgments, viii 1 Introduction to the Classification of Lymphoma 1 Kiel Lukes–Collins, and Working Formulation classifications 1 WHO, REAL, EORTC, and the Combined WHO/EORTC classifications 2 Summary 7 References 8 Appendix: Definitions of key terms and techniques 9 2 The Therapy of Cutaneous T Cell Lymphoma 14 Benjamin H. Kaffenberger, Mark A. Bechtel, and Pierluigi Porcu Introduction 14 Diagnostic work-up and staging procedures 14 CTCL therapies 15 Goals of therapy in advanced-stage CTCL 16 Extracorporeal photopheresis (ECP) 17 Interferons 17 Retinoids 17 Immunotoxins 18 Monoclonal antibodies 18 Histone deacetylase inhibitors (HDACi) 19 Antibody drug conjugates (ADC) 19 Cytotoxic chemotherapy 19 Investigational therapies 20 TLR agonists and cytokines 20 Allogeneic hematopoietic stem cell transplantation (allo-HSCT) 20 References 21 3 Molecular Analysis in Cutaneous Lymphoid Proliferation 23 Shabnam Momtahen, Cynthia Magro, and Carl Morrison Introduction 23 Immunoglobulin and T cell receptor structure 23 PCR design for determination of clonality 24 Detection of PCR products for clonality 24 Evaluation of results 25 The value and utility of molecular diagnostics in primary cutaneous lymphomas 26 Limitations of clonality assessment by PCR 27 Case vignettes 29 References 36 4 Benign Lymphocytic Infiltrates 37 Introduction 37 Spongiotic and eczematous dermatitis 37 Other spongiotic/eczematous tissue reactions 40 Other causes of subacute eczematous dermatitis 40 Interface dermatitis: cell-poor vacuolar interface dermatitis 42 Interface dermatitis: lichenoid pattern 46 Diffuse and nodular lymphocytic dermal infiltrates without atypia 51 Diffuse and nodular lymphocytic infiltrates associated with autoimmune disease 53 References 57 5 Reactive Lymphomatoid Tissue Reactions Mimicking Cutaneous T and B Cell Lymphoma 59 Lymphomatoid drug eruptions 59 Molecular profile of lymphomatoid drug eruptions 61 Pathogenetic basis of lymphomatoid drug reactions 62 Reactive lymphomatoid lesions encountered in lesions of collagen vascular disease 63 Angiomatous Variants of Pseudolymphoma 67 Case vignettes 69 References 86 6 Precursor Lesions of Cutaneous T Cell Lymphoma 89 Cutaneous T cell lymphoid dyscrasia 89 Large plaque parapsoriasis 90 Hypopigmented interface T cell dyscrasia: a unique indolent T cell dyscrasia 91 Pigmented purpuric dermatosis (PPD) 92 Pityriasis lichenoides 94 Idiopathic erythroderma (pre-Sézary) 96 Syringolymphoid hyperplasia with alopecia 96 Folliculotropic T cell lymphocytosis/pilotropic T cell dyscrasia 97 Idiopathic follicular mucinosis/alopecia mucinosa 98 Keratoderma-like T cell dyscrasia 99 Atypical lymphocytic lobular panniculitis 100 Case vignettes 102 References 132 7 Marginal Zone Lymphoma and Other Related Post Germinal Center B Cell Lymphoproliferative Disorders of The Skin 134 Marginal zone lymphoma 134 Blastic marginal zone lymphoma 140 Epidermotropic marginal zone lymphoma 140 Castleman disease 141 Primary cutaneous plasmacytoma 142 Case vignettes 145 References 166 8 Primary Cutaneous Follicle Center Cell Lymphoma 169 Clinical features 169 Pathology 169 Phenotypic profile 171 Molecular studies 172 Pathogenesis 172 Cytogenetics 172 Case vignettes 174 Additional molecular and cytogenetic study 185 References 186 9 Primary Cutaneous Diffuse Large B-Cell Lymphoma Including the Leg Type and Precursor B Cell Lymphoblastic Lymphoma 187 Primary cutaneous diffuse large B cell lymphoma 187 Systemic diffuse large B cell lymphomas with a propensity to involve the skin 197 Case vignettes 200 Additional light microscopic, phenotypic, molecular, cytogenetic studies 210 References 215 10 Intravascular Lymphoma 218 Clinical features 218 Light microscopic findings 219 Phenotypic profile 219 Molecular and cytogenetic studies 219 Pathogenesis 219 Differential diagnosis 219 Intravascular anaplastic large cell lymphoma 219 Benign intravascular proliferations of histiocytes and reactive T cells 220 Case vignettes 221 References 224 11 Cutaneous Mantle Cell Lymphoma 225 Clinical features 225 Light microscopic findings 225 Phenotypic profile 226 Molecular studies 227 Cytogenetic profile 227 Pathogenesis 227 Case vignettes 229 Additional molecular and cytogenetic studies 233 References 234 12 Mycosis Fungoides and Sézary Syndrome 236 Definition 236 Mycosis fungoides 236 Sézary syndrome and erythrodermic mycosis fungoides 243 Large cell transformation of mycosis fungoides 251 Extracutaneous involvement in mycosis fungoides 254 Case vignettes 259 References 271 13 CD30-Positive Lymphoproliferative Disorders Including Lymphomatoid Papulosis, Borderline CD30-Positive Lymphoproliferative Disease, Anaplastic Large Cell Lymphoma, and T-Cell-Rich CD30-Positive Large B Cell Lymphoma 274 Introduction 274 Lymphomatoid papulosis 274 CD8+ lymphomatoid papulosis, including the type D variant 278 Type E lymphomatoid papulosis (Case vignette 15) 278 Borderline CD30-positive lymphoproliferative disorders (type C LYP) (Case vignette 9) 279 Lymphomatoid papulosis with a rearrangement of chromosome 6p25.3 279 Cutaneous anaplastic large cell lymphoma 280 Small cell ALCL 282 Additional unusual histologic variants of anaplastic large cell lymphoma 282 Breast-implant-associated anaplastic large cell lymphoma 282 Intravascular anaplastic large cell lymphoma 282 Sarcomatoid anaplastic large cell lymphoma (Case vignette 14) 283 CD30-positive large B cell lymphoma 285 Case vignettes 286 References 309 14 CD4+ Peripheral T Cell Lymphoma, Not Otherwise Specified, Including Primary Cutaneous Cd4+ Small/Medium-Sized Pleomorphic T Cell Lymphoma 312 Introduction 312 Primary cutaneous CD4+ small/medium-sized pleomorphic T cell lymphoma 312 CD30-negative large cell T cell lymphoma 313 Cutaneous follicular helper T cell lymphoma 314 Overview of overall prognosis of primary cutaneous peripheral T cell lymphoma, unspecified 315 Evolution of the nomenclature of primary cutaneous CD4+ small/medium-sized pleomorphic T cell lymphoma 319 Case vignettes 320 References 333 15 Subcutaneous Panniculitis-Like T Cell Lymphoma 334 Clinical features 334 Morphology 336 Phenotype 337 Molecular studies 337 Differential diagnosis 337 Case vignettes 340 References 349 16 CD8 T Cell Lymphoproliferative Disease of the Skin 351 Overview 351 Introduction 351 Classification of primary CD8+ cutaneous T cell lymphomas 352 Histomorphology of primary cutaneous CD8+ T cell lymphoma: primary cutaneous aggressive epidermotropic CD8+ T cell lymphoma, and CD8+ variants of peripheral T cell lymphoma, NOS, including primary cutaneous CD8+ granulomatous T cell lymphoma 353 CD8 variant of lymphomatoid papulosis and other related CD30-positive T cell lymphoproliferative disorders of CD8 subtype 354 Light microscopic findings 354 Indolent CD8 positive lymphoid proliferation of the face and other body sites including acral surfaces 355 CD8 prolymphocytic leukemia 355 CD8 pseudolymphoma related to underlying HIV disease 356 Drug-associated CD8+ pseudolymphoma 356 Actinic reticuloid as a unique form of CD8+pseudolymphoma 356 Case vignettes 357 References 375 17 Nasal and Related Extranodal Natural Killer Cell/T Cell Lymphomas and Blastic Plasmacytoid Dendritic Cell Neoplasm 377 Introduction 377 Biology of NK and NK-like T cells 377 NK/T-cell lymphoma 379 Nasal NK/T cell lymphoma 379 Nasal type NK/T cell lymphoma 380 Aggressive NK cell lymphoma 380 Role of Epstein–Barr virus in the evolution of NK/T cell lymphomas 382 Blastic plasmacytoid dendritic cell neoplasm 382 CD56-positive γ δ lymphoma involving the subcutaneous fat 383 Chronic granular lymphocytosis/large granular cell leukemia 384 Natural killer-like CD4+ T cell lymphoma 384 EBV-associated NK/T cell lymphomas of the elderly 385 Hydroa vaccineforme (HV)-like lymphoma 385 Cutaneous intravascular NK T cell lymphoma 386 Case vignettes 387 References 401 18 Primary Cutaneous γ δ T Cell Lymphoma 404 Introduction 404 Case vignettes 409 Additional supplemental figures 411 References 414 19 Epstein–Barr Virus-Associated Lymphoproliferative Disease 415 Introduction 415 Hydroa vacciniforme-like EBV-associated T cell lymphoproliferative disease/mosquito bite hypersensitivity 416 EBV+ cutaneous B cell lymphoproliferative disorder of the elderly 420 EBV-associated mucocutaneous ulcer 421 EBV + T cell lymphoproliferative disease of the elderly 421 General principles regarding EBV-associated lymphomagenesis 421 Pathogenetic link between EBV-associated B cell lymphoma and iatrogenic immune dysregulation related to either methotrexate or cyclosporine 421 Case vignettes 423 References 432 20 Hodgkin Lymphoma of the Skin 435 Clinical features 435 Subtypes of Hodgkin lymphoma 436 References 447 21 Chronic Lymphocytic Leukemia of B Cell and T Cell Prolymphocytic Leukemia 449 B cell chronic lymphocytic leukemia 449 T cell prolymphocytic leukemia 452 Case vignettes 455 References 471 22 Adult T Cell Leukemia/Lymphoma 473 Clinical features 473 Pathology 474 Phenotypic studies 475 Pathogenesis 475 Infective dermatitis of childhood 476 Case vignettes 477 References 484 23 Angioimmunoblastic Lymphadenopathy/Angioimmunoblastic T Cell Lymphoma 486 Clinical features 486 Light microscopic findings 487 Phenotypic studies 488 Molecular studies 488 Pathogenesis 489 Case vignettes 491 References 497 24 Lymphomatoid Granulomatosis 499 Introduction 499 Clinical features 499 Histopathology 500 Histogenesis 501 Clonality studies 501 Differential diagnosis 501 Treatment 502 Case vignette 503 References 506 25 Cutaneous Infiltrates of Myeloid Derivation 507 Introduction 507 Leukemia cutis 507 Clonal histiocytopathy syndromes 509 Histiocytopathy of factor XIIIA perivascular dermal dendritic cell origin 514 Case vignettes 517 References 537 Index 541
£260.06
John Wiley and Sons Ltd Endocrinology
Book SynopsisTable of ContentsPreface xix Acknowledgments xx CHAPTER 1 Pituitary Gland Therapies 1 1.1 Cushing's Disease 1 1.2 Acromegaly 10 1.3 Prolactinoma 15 1.4 Adult Growth Hormone Insufficiency 19 1.5 Central Diabetes Insipidus 22 1.6 Syndrome of Inappropriate ADH Secretion 28 CHAPTER 2 Thyroid Gland Therapies 43 2.1 Hashimoto's Thyroiditis 43 2.2 Graves' Disease and Thyroid Eye Disease 51 2.3 Riedel's Thyroiditis 60 2.4 Thyroid Hormone Resistance 61 2.5 TSH-Secreting Tumors 64 2.6 Thyroid Cancer 65 CHAPTER 3 Adrenal Gland Therapies 83 3.1 Primary Adrenal Insufficiency 83 3.2 Primary Hyperaldosteronism 91 3.3 Pheochromocytomas and other Paraganglioma Syndromes 96 3.4 Classic Congenital Adrenal Hyperplasia 103 3.5 Nonclassic Congenital Adrenal Hyperplasia 106 CHAPTER 4 Pancreatic Gland Therapies 122 4.1 Diabetes Mellitus 122 4.2 Neuroendocrine Tumors 148 4.3 Hypoglycemia Syndromes 154 CHAPTER 5 Parathyroid Gland and Bone Therapies 171 5.1 Primary Hyperparathyroidism 171 5.2 Hypoparathyroidism 176 5.3 Paget's Disease of Bone 184 5.4 X-Linked Hypophosphatemia 186 5.5 Osteoporosis 189 CHAPTER 6 Reproductive Organ Therapies 215 6.1 Polycystic Ovary Syndrome 215 6.2 Male Hypogonadism 230 6.3 Menopause 238 6.4 Turner's Syndrome 242 CHAPTER 7 Therapies in Disorders of Lipid Metabolism and Obesity 256 7.1 Hyperlipoproteinemia Syndromes 256 7.2 Obesity 271 7.3 Lipodystrophy Syndromes 280 CHAPTER 8 Miscellaneous Topics in Disorders of Endocrine Glands 295 8.1 Recent Technological Advances in Diabetes Care 295 8.2 Immune Checkpoint Inhibitor-Related Endocrinopathies 299 8.3 Pseudoendocrine Conditions 301 8.4 Drugs of Abuse with Endocrine Side Effects 303 CHAPTER 9 Dynamic Tests in Clinical Endocrinology 313 9.1 Pituitary Gland 313 9.2 Disorders of the Thyroid Gland 323 9.3 Disorders of the Adrenal Glands 326 9.4 Disorders of the Pancreas 329 9.5 Disorders of the Reproductive Organs 332 Appendix A 343 A.1 Cardiovascular Outcome Trials in Diabetes Care 343 A.2 Common Side Effects of Endocrine Treatments (Board Review) 344 A.3 Brand Names of Common Medications in Endocrinology 346 Index 348
£56.04
John Wiley & Sons Applied Pathophysiology for the Advanced Practice
Book Synopsis
£85.50
John Wiley and Sons Ltd Pathology of Sudden Cardiac Death
Book SynopsisPathology of Sudden Cardiac Death provides a comprehensive review of cardiovascular disorders. While sudden cardiac death could primarily be seen as an arrhythmogenic event, this actually represents the minority of cases. For the vast majority, there is an underlying anatomic disorder of the cardiovascular system responsible for the ultimate hemodynamic collapse known as sudden cardiac death. Although an increasing array of non-invasive diagnostic tools continue to develop, many physicians and operators of these new diagnostic modalities have never actually seen specimens which demonstrate the fundamental pathologic abnormalities. By providing an atlas style review of ischemic and non-ischemic etiologies of sudden cardiac death, this book opens a window to see the underlying pathology first hand.Table of ContentsPreface. Foreword. Introduction. Acknowledgments. 1. Atherosclerotic coronary disease. 2. Nonatherosclerotic coronary disease. 3. Myocardial disease. 4. Diseases of the conduction system. 5. Systemic hypertension. 6. Valvular heart disease. 7. Metabolic and infiltrative disorders. 8. Tumors and blood dyscrasias. 9. Great vessels and related structures. 10. Diseases of the pericardium. 11. Multi-organ system diseases. References. Index.
£90.86
John Wiley and Sons Ltd Instant Pathology
Book SynopsisIndispensable dip-in revision aid Instant Pathology is the latest addition to the Instant series of basic science revision aids. It presents the fundamental pathological information needed for clinical practice in an easily accessible dip-in format.Trade Review"If you are looking for a book that covers pathology in an easy to understand way, then this is the book for you. I would highly recommend this book to medical students and junior doctors alike. A real gem." Medical Student, Manchester University "Short bursts of text and lots of bullet points make absorbing the information child's play." SHO, University Hospital Birmingham "Excellent format for quick assimilation of knowledge." SHO, West Middlesex University Hospital "The definitions and epidemiological facts are clear and concisely written." Clinical Lecturer in Histopathology, Bristol "Instant Pathology is a really simple book that gives you the basic information you need for last minute revision...It is easy to read with short sections on each disease. It has a clear layout making learning quick and easy" Medical Student, Oxford University “A quick reference for…students…Written in a student-friendly way, this book will be most useful to senior medical students who wish to review pathology.” Doody’s Book ReviewsTable of ContentsPreface. . List of abbreviations. . 1: General histopathology. Terminology. Acute inflammation. Chronic inflammation. Repair (healing) and regeneration. Neoplasia and carcinogenesis. Cell cycle and apoptosis. Tissue sampling and biopsy. Tissue fixation and preparation. Tissue examination and observation. Immunohistochemistry. Genetics in disease. Using the histopathology department. . 2: Vascular pathology. Thrombosis and embolism. Atheroma and atherosclerosis. Arteritis and vasculitis. Aneurysmal disease. Myocarditis and cardiomyopathy. Endocarditis. Vascular tumours. Pericarditis. 3: Respiratory pathology. Pneumonia and lower respiratory tract infection. Bronchiectasis. Pulmonary tuberculosis. Fibrotic lung disease. Chronic obstructive pulmonary disease. Malignant bronchogenic tumours. Other respiratory tumours. Sarcoidosis. 4: Gastrointestinal pathology. Oesophageal carcinoma. Peptic ulcer disease and gastritis. Gastric carcinoma. Crohn’s disease. Inflammatory small bowel diseases. Colitis. Colorectal neoplasia. Pancreatitis. Pancreatic tumours. Gallstones and related gallbladder pathologies. Biliary tumours. Hepatitis. Alcoholic liver disease. Non alcoholic cirrhosis. Liver tumours. 5: Genitourinary pathology. Glomerulonephritis. Nephrotic syndrome. Renal tumours. Urinary epithelial tumours. Prostatic disorders. Testicular tumours. 6: Breast pathology. Breast carcinoma. Abnormalities of Normal Development and Involution (ANDI). Other benign breast disorders. 7: Gynaecological pathology. Endometriosis. Leiomyoma. Endometrial hyperplasia and neoplasms. Cervical carcinoma. Ovarian epithelial tumours. Ovarian non-epithelial tumours. 8: Endocrine pathology. Non-neoplastic adrenal disease. Neoplastic adrenocortical disorders. Neoplastic adrenomedullary disorders. Non neoplastic thyroid disease. Thyroid tumours. Parathyroid and multiple endocrine disorders. 9: Bone pathology. Inflammatory bone diseases. Paget’s disease. Osteoporosis (generalised). Benign bone tumours. Malignant bone tumours. 10: Skin pathology. Benign skin diseases. Benign skin tumours. Malignant skin tumours. Malignant melanoma. 11: Neuropathology. Encephalitis. Meningitis. Degenerative disorders. Demyelinating disorders. Neurologic vascular events. Peripheral nervous system tumours. Benign intracranial tumours. Malignant central nervous system tumours. 12: Rheumatological/immunological pathology. Rheumatoid arthritis. Other autoimmune arthritides. Amyloidosis. Index
£29.40
Springer-Verlag New York Inc. Radioguided Surgery
Book SynopsisThis multidisciplinary textbook is designed to be the standard on the subject and is geared for use by physicians who are involved in the care and/or diagnosis of cancer patients. A wealth of illustrations, including a full-color insert, enhances the application of new concepts.Trade ReviewFrom the reviews: "This is a multidisciplinary book covering all aspects of radioisotope guided surgery for all practitioners involved in the field. The book distinguishes itself from others in the field by the clarity and breadth of explanation … . This is intended primarily for those actually involved in the field -- not just surgeons, but all physicians involved in the care of cancer patients … . Practitioners and trainees in the subspecialty fields of surgical oncology, endocrine surgery, nuclear medicine, and pathology will find it of use." (Carol EH Scott-Conner, MD, PhD, Doody’s Review Service, March, 2008) "This is a new, updated publication, which has the merit of giving wide and deep information about a field, radioguided surgery … . It is designed with a multidisciplinary approach and addressed not only to nuclear physicians but also to surgeons, oncologists, pathologists … . In conclusion, the book is an original and effective publication that we recommend to all physicians both qualified and in training, including students, who are already working in the field … ." (Vincenzo Cuccurullo and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 36, 2009)Table of Contents*Anatomy and physiology of lymphatic circulation as it relates to metastatic spread of solid cancers *The role of lymph node staging for clinical decision making in patients with solid cancers *Techniques to identify sentinel lymph nodes in patients with: Breast cancer, Melanoma, Penile carcinoma, Head and neck cancer, Ovarian cancer, Vulvar cancer, Endometrial cancer, Cancers of the gastrointestinal tract and pancreas, Neuroendocrine tumors, Prostate cancer, Non-small cell lung cancer *Histopathology of sentinel lymph nodes: Imprint cytology in sentinel lymph node biopsy, Conventional histology and immunohistochemistry, Molecular biology techniques for sentinel lymph nodes *Non-sentinel-node applications of radioguided surgery: Breast cancer, Parathyroid tumors, Neuroendocrine tumors, Solitary lesions in the lung, Thyroid cancer, Present role of radioimmunoguided surgery *The perspective of the nuclear medicine physician, the surgeon, and the pathologist *Radiopharmaceuticals for radioguided surgery *Instrumentation: Physical performance parameters of intraoperative probes, and other technical issues of radioguided surgery, Imaging probes and positron-sensitive probes *Radiation protection issues in radioguided surgery *Training and credentialing for radioguided surgery
£89.99
John Wiley and Sons Ltd Identification of Pathogenic Fungi
Book SynopsisSince the first edition of Identification of Pathogenic Fungi, there has been incredible progress in the diagnosis, treatment and prevention of fungal diseases: new methods of diagnosis have been introduced, and new antifungal agents have been licensed for use. However, these developments have been offset by the emergence of resistance to several classes of drugs, and an increase in infections caused by fungi with innate resistance to one or more classes. Identification of Pathogenic Fungi, Second Edition, assists in the identification of over 100 of the most significant organisms of medical importance. Each chapter is arranged so that the descriptions for similar organisms may be found on adjacent pages. Differential diagnosis details are given for each organism on the basis of both colonial appearance and microscopic characteristics for the organisms described. In this fully updated second edition, a new chapter on the identification of fungi in histopaTrade Review“Clinicians, microbiology laboratory personnel, and students will all find this reference source valuable.” (Clinical Infectious Diseases, 22 August 2014) Table of ContentsPreface, ix Acknowledgements, xi 1 Introduction, 1 2 Identification of Moulds, 11 Media for Mould Identification, 14 Mounting Fluids, 16 3 Moulds with Arthrospores, 18 Neoscytalidium dimidiatum, 20 Coccidioides species, 24 Onychocola canadensis, 28 4 Moulds with Aleuriospores: I. The Dermatophytes, 31 Microsporum gypseum, 38 Microsporum canis, 40 Microsporum equinum, 42 Epidermophyton floccosum, 44 Trichophyton terrestre, 46 Trichophyton rubrum, 48 Trichophyton interdigitale, 52 Trichophyton mentagrophytes, 54 Trichophyton erinacei, 56 Trichophyton equinum, 58 Trichophyton soudanense, 60 Microsporum persicolor, 62 Trichophyton tonsurans, 64 Microsporum audouinii, 66 Trichophyton violaceum, 68 Trichophyton verrucosum, 70 Trichophyton schoenleinii, 72 Trichophyton concentricum, 74 Other Microsporum and Trichophyton species, 76 5 Moulds with Aleuriospores: II. Others, 80 Geomyces pannorum, 82 Chrysosporium keratinophilum, 84 Myceliophthora thermophila, 86 Histoplasma capsulatum, 88 Blastomyces dermatitidis, 92 Paracoccidiodes brasiliensis, 96 6 Moulds with Holoblastic Conidia, 99 Aureobasidium pullulans, 102 Sporothrix schenckii, 104 Cladophialophora bantiana, 106 Cladosporium sphaerospermum, 108 Fonsecaea pedrosoi, 110 Rhinocladiella atrovirens, 112 Rhinocladiella mackenziei, 114 Ochroconis gallopava, 116 Alternaria alternata, 118 Ulocladium chartarum, 120 Curvularia lunata, 122 Bipolaris hawaiiensis, 124 Exserohilum rostratum, 126 7 Moulds with Enteroblastic Conidia Adhering in Chains, 129 Aspergillus flavus species complex, 134 Aspergillus fumigatus species complex, 136 Aspergillus glaucus, 138 Aspergillus nidulans species complex, 140 Aspergillus versicolor species complex, 142 Aspergillus ustus species complex, 144 Aspergillus niger species complex, 146 Aspergillus terreus species complex, 148 Aspergillus candidus species complex, 150 Penicillium marneffei, 152 Scopulariopsis brevicaulis, 154 Purpureocillium lilacinum, 156 Paecilomyces variotii, 158 8 Moulds with Enteroblastic Conidia Adhering in Wet Masses, 161 Fusarium lichenicola, 166 Fusarium dimerum species complex, 168 Fusarium semitectum, 170 Fusarium proliferatum, 172 Fusarium oxysporum species complex, 174 Fusarium solani species complex, 176 Acremonium strictum, 178 Acremonium kiliense, 180 Lecythophora mutabilis, 182 Scedosporium prolificans, 184 Scedosporium apiospermum, 186 Phaeoacremonium parasiticum, 188 Pleurostomophora richardsiae, 190 Phialophora verrucosa, 192 Hortaea werneckii, 194 Exophiala spinifera, 196 Exophiala dermatitidis, 198 Exophiala jeanselmei, 200 9 Mucoraceous Moulds and Their Relatives, 203 Cunninghamella bertholletiae, 208 Lichtheimia corymbifera, 210 Rhizomucor pusillus, 212 Mucor circinelloides, 214 Rhizopus microsporus, 216 Rhizopus arrhizus, 218 Mucor hiemalis, 220 Basidiobolus ranarum, 222 Conidiobolus coronatus, 224 Pythium insidiosum, 226 Apophysomyces elegans, 228 Saksenaea vasiformis, 230 Mortierella wolfii, 232 10 Miscellaneous Moulds, 235 Aphanoascus fulvescens, 238 Monascus ruber, 240 Chaetomium species, 242 Phoma herbarum, 244 Myxotrichum deflexum, 246 Schizophyllum commune, 248 Leptosphaeria senegalensis, 250 Neotestudina rosatii, 252 Piedraia hortae, 254 Lasiodiplodia theobromae, 256 Pyrenochaeta romeroi, 258 Madurella mycetomatis, 260 11 Identification of Yeasts, 263 Media for Yeast Identification, 272 Candida albicans, 274 Candida tropicalis, 276 Candida krusei, 278 Candida lipolytica, 280 Candida kefyr, 281 Candida lusitaniae, 282 Candida parapsilosis, 284 Candida pelliculosa, 286 Candida guilliermondii, 287 Candida glabrata, 288 Cryptococcus neoformans and Cryptococcus gattii, 290 Rhodotorula glutinis, 292 Saccharomyces cerevisiae, 294 Geotrichum candidum, 296 Saprochaete capitata, 298 Trichosporon species, 300 Malassezia furfur species complex, 302 Malassezia pachydermatis, 304 12 Identification of Fungi in Sections, Smears and Body Fluids, 305 Appendix 1: Common Mycological Terms, 321 Appendix 2: Further Reading, 325 Species Index, 327 Subject Index, 333
£106.16
Springer-Verlag New York Inc. Serous Cavity Fluid and Cerebrospinal Fluid
Book SynopsisThis volume offers an easy-to-use and authoritative synopsis of site specific topics in cytopathology. This compact, heavily illustrated guide book fits into a lab coat pocket, making it an ideal quick reference.Table of Contents1. Introduction, Clinical and Technical Aspects2. Normal Cytology3. Reactive Mesothelial Hyperplasia4. Malignant Mesothelioma5. Metastatic Cancers6. Effusions in Children7. Abdomino-pelvic Washings8. Lymphocytic Effusions9. Benign Inflammatory and Other Uncommon Conditions
£98.99
Springer The Principles of Clinical Cytogenetics
Book SynopsisHistory of Clinical Cytogenetics.- DNA, Chromosomes, and Cell Division.- Human Chromosome Nomenclature: An Overview and Definition of Terms.- Basic Cytogenetics Laboratory Procedures.- The Essentials of Light Microscopy.- Quality Control & Quality Assurance.- Instrumentation in the Cytogenetics Laboratory.- Autosomal Aneuploidy.- Structural Chromosome Rearrangements.- Sex Chromosomes, Sex Chromosome Disorders, and Disorders of Sex Development.- The Cytogenetics of Infertility.- Prenatal Cytogenetics.- The Cytogenetics of Spontaneous Abortion.- Chromosome Instability.- The Cytogenetics of Hematologic Neoplasms.- The Cytogenetics of Solid Tumors.- Fluorescence in situ Hybridization (FISH).- Microarray-Based Cytogenetics.- Fragile X: A Family of Disorders: Changing Phenotype and Molecular Genetics.- Genomic Imprinting and Uniparental Disomy.- Genetic Counseling.Trade ReviewFrom the reviews of the third edition:“The audience includes those performing clinical cytogenetic testing or using results for genetic counseling or clinical care. It also would be of interest to anyone interested in cytogenetic analysis and application, from healthcare providers … to the educated lay public. … This is truly a remarkable and comprehensive book on clinical cytogenetics. … You would also want this book as a handy reference for which genetic abnormality is associated with what disease, and the best test method to use to identify the suspected abnormality.” (Valerie Ng, Doody’s Book Reviews, July, 2013)Table of ContentsSECTION 1 - Basic Concepts and Background1. History of Clinical CytogeneticsSteven L. Gersen2. DNA, Chromosomes, and Cell Division Martha B. Keagle3. Human Chromosome Nomenclature: An Overview and Definition of TermsMarilyn L. Slovak, Aaron Theisen, and Lisa G. ShafferSECTION II - Examining and Analyzing Chromosomes4. Basic Cytogenetics Laboratory ProceduresMartha B. Keagle and Steven L. Gersen5. The Essentials of Light MicroscopyNathan Claxton and Stephen Ross6. Quality Control & Quality AssuranceMartha B. Keagle7. Instrumentation in the Cytogenetics LaboratorySteven L. GersenSECTION III – Clinical Cytogenetics8. Autosomal AneuploidyJin-Chen C. Wang9. Structural Chromosome RearrangementsKathleen Kaiser-Rogers and Kathleen Rao10. Sex Chromosomes, Sex Chromosome Disorders, and Disorders of Sex DevelopmentCynthia M. Powell11. The Cytogenetics of InfertilityLinda Marie Randolph12. Prenatal CytogeneticsLinda Marie Randolph13. The Cytogenetics of Spontaneous AbortionSolveig M. V. Pflueger14. Chromosome InstabilityXiao-Xiang ZhangSECTION IV – Cancer Cytogenetics15. The Cytogenetics of Hematologic NeoplasmsAurelia Meloni-Ehrig16. The Cytogenetics of Solid Tumors Linda D. Cooley and Kathleen S. WilsonSECTION V - Adjunct Technologies17. Fluorescence in situ Hybridization (FISH)Daynna J. Wolff18. Microarray-Based CytogeneticsLisa G. ShafferSECTION VI – Beyond Chromosomes19. Fragile X: A Family of Disorders: Changing Phenotype and Molecular GeneticsElaine B. Spector 20. Genomic Imprinting and Uniparental DisomyJin-Chen C. Wang21. Genetic CounselingSarah Hutchings Clark
£189.99
Springer-Verlag New York Inc. Vitreous
Book SynopsisThe vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how vitreous is composed and what role it plays in normal physiology as well as pathology. Over the years, however, many studies have produced important findings concerning vitreous biochemistry, structure, physiology, and pathobiology. Published on the 25th anniversary of Sebag''s first book on Vitreous, this second installment is nearly five times longer than its predecessor, reflecting how much has been learned in the past quarter century. This well-constructed compendium not only addresses the most current scientific knowledge, but also reviews clinical perspectives in a manner that lends richness to the scope of the book. Written by 90 authors, this book has 56 chapters organized into 7 sections: Biochemistry; Anatomy, Development, and Aging; Pathology/Pathobiology; PhysiTrade Review“A striking feature of this textbook is the stunningly vivid color illustrations that have remarkable resolution, in spite of considerably large size. Graphs and tables are featured in both grayscale and color, adding significantly to the ease of comprehension when reading this book. … this book is not only useful to skilled clinicians and expert scientists, but also students, as the book has no competition anywhere in the world.” (Taiji Sakamoto, Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 257, 2019) Table of ContentsPREFACE: J. SebagFOREWORD: D. Jackson Coleman and Harvey LincoffINTRODUCTION: Is your vitreous really necessary? - Professor Wallace F Foulds I. BIOCHEMISTRY - Professor Paul Bishop, Section EditorA. Vitreous Proteins – PB Bishop B. Hyaluronan and other Carbohydrates in the Vitreus– JL Denlinger, EA Balazs C. Hereditary Vitreo-Retinopathies – M P Snead, A J Richards D. Vitreous Proteomics and Regression of the Fetal Hyaloid Vasculature – KMP Yee, L P Aiello, MC Madigan, A A Sadun, J Sebag E. Diabetic Vitreopathy – J Gale, L P Aiello, J Sebag F. Vitreous Biochemistry & Artificial Vitreous - S Crafoord, F Ghosh, J Sebag II. ANATOMY, DEVELEOPMENT & AGING - Dr. J. Sebag, Section Editor A. Development and Developmental Disorders of Vitreous - Z S Kingston, J M Provis, M C Madigan B. Myopic Vitreopathy – J Gale, Y Ikuno C. Vitreous Aging & Posterior Vitreous Detachment – K Tozer, M Johnson, J Sebag D. Hyalocytes: Essential Vitreous Cells in Vitreo-Retinal Health & Disease – T Kita, T Sakamoto, T Ishibashi E. Vitreo-Retinal Interface & Inner Limiting Membrane – W Halfter, E Cunningham, J Sebag F. To See the Invisible - the Quest of Imaging Vitreous-J Sebag, RH Silverman, D J ColemanIII. PATHOLOGY/PATHOBIOLOGY - Dr. J. Sebag, Section EditorA. Congenital Vascular Vitreo-Retinopathies - M E Hartnett, R HobbsB. Anomalous Posterior Vitreous Detachment & Vitreoschisis - J Sebag, M Niemeyer, MJ KossC. Pathology of Vitreo-Maculopathies - A Gandorfer, R Schumann, C Haritoglou, A KampikD. Vitreo-Macular Adhesion/Traction & Macular Holes - Pseudo, Lamellar & Full-Thickness - M Englander, JS Duker, PK KaiserE. Vitreo-Papillary Adhesion and Traction - MY Wang, AA Sadun, J SebagF. Vitreous in the Pathobiology of Macular Pucker – K Tozer, J Sebag G. Vitreous in Age-related Macular Degeneration – I Krebs, C Glittenberg, S Binder H. Peripheral Vitreo-Retinal Pathology - J Sebag, S Dunker, WR GreenI. Role of Vitreous in the Pathogenesis of Retinal Detachment –W Foulds J. Cell Proliferation at the Vitreo-Retinal Interface in Proliferative Vitreo-Retinopathy and Related Disorders – S Mehta, R Zhang, HE Grossniklaus K. Vitreous in Retino-Vascular Diseases and Diabetic Macular Edema – GE Lang L. Proliferative Diabetic Vitreo-Retinopathy –P Kroll, EB Rodrigues, CH Meyer IV. PHYSIOLOGY & PHARMACOTHERAPY - Professor Einar Stefansson, Section EditorA. Vitreous Physiology – E Stefánsson B. Oxygen in Vitreo-Retinal Physiology and Pathology - N Hollekamp, D Beebe, Y B ShuiC. Vitreous and Iris Neovascularization - D McLeodD. Physiology of Accommodation & Role of Vitreous - D J Coleman & R H Silverman & H Lloyd E. Principles and Practice of Intravitreal Application of Drugs – P Lin, S Mehda, E deJuan F. Pharmacotherapy of Proliferative Vitreo-Retinopathy – P J Banerjee, D G Charteris, D Wong G. (SiO, PFCs) - I Y Wong, N Cheung, D Wong V. VITREO-RETINAL SURGERY A. Posterior Vitreo-Retinal Surgery - Professor Susanne Binder, Section Editor1. Age-Related Macular Degeneration Surgery - S Binder, L P Chong 2. Vitreo-Maculopathy Surgery – M Figueroa, I Contreras 3. Chromodissection in Vitreo-Retinal Surgery – C Haritoglou, A Gandorfer A Kampik 4. Macular Hole & Macular Pucker Surgery with Special Emphasis on Re-Operations – B Pan, K M P Yee, F N Ross-Cisneros, A A Sadun, J Sebag5. Surgery of Diabetic Vitreo-Retinopathy & Diabetic Macular Edema - S Brunner & S Binder 6. Vitreous Surgery of Arterial and Venous Retino-Vascular Diseases – J Garcia-Arumi & S Binder, M Leila, M Victori B. Peripheral Vitreo-Retinal Surgery - Dr. Lawrence P. Chong, Section Editor1. The History of Vitrectomy Instrumentation – J M Parel2. Modern Vitrectomy Cutters – L P Chong 3. The Future of Vitrectomy – J P Hubschman, S U Shah, V B Voleti4. Prophylaxis and Cure of Retinal Detachment – C P Wilkinson 5. Management of Proliferative Vitreo-Retinopathy- A. N. Mehta & G. W. Abrams 6. Retinectomy in Recalcitrant Retinal Detachments – L. P. Chong 7. Pneumatic Retinopexy – K M P Yee and J Sebag 8. Floaters and Vision - Current Concepts and Management Paradigms L. C. Huang, K M P Yee, C A Wa, A A Sadun, J Sebag 9. Rare Indications for Vitrectomy: Tumor Excision, Optic Nerve Pits, Malignant Glaucoma - L P Chong VI. PHARMACOLOGIC VITREOLYSIS - Dr. J. Sebag, Section EditorA. Pharmacologic Vitreolysis - J Sebag B. The History of Pharmacologic Vitreolysis - W S Foulds C. Pharmacologic Vitreolysis with Tissue Plasminogen Activator – P Kroll & H HesseD. Pharmacologic Vitreolysis with Plasmin 1. Basic Science Experiments - Th Verstraeten 2. Clinical Studies - H Terasaki & T Asami E. Pharmacologic Vitreolysis with Ocriplasmin 1. Basic Science Studies - M deSmet & B Jonkcx 2. Clinical Studies - P Stalmans F. Hyaluronidase as a Vitreous Liquefactant - M deSmet, L Grillone G. Pharmacologic Vitreolysis with Dispase (Vitreolysin™) - T H Tezel, L. Del Priore, H J KaplanH. Chondroitinase as a Vitreous Interfactant - Vitreous Dis-insertion in the Human - S R Russell, G S Hageman
£179.99
Thieme Medical Publishers Inc Thieme Test Prep for the USMLE®: Pathology Q&A
Book SynopsisThieme Test Prep for the USMLE®: Pathology is the choice of medical students... ...I am very impressed ...These answers and explanations waste no time getting right to the point and hit the high-yield points a student must know... for the USMLE® Step 1 exam. - Nicholas T. Gamboa, MS-II (Second-year medical student, University of Utah School of Medicine) These path questions really tested the concepts succinctly and directly. - Amy Leshner (Fourth-year medical student, Chicago College of Osteopathic Medicine) ...The major test-prep resources do not focus on these subjects in detail. A question bank...would be beneficial to those who struggle with these as an additional resource for studying ... - Ethan Young (Fourth-year medical student, University of South Dakota, Sanford School of Medicine) Thieme Test Prep for the USMLE®: Pathology provides medical students studying for boards with a thorough review of pathology concepts. Co-authored by a pathologist and family practice physician, this robust test prep tool combines pathology with strong clinical correlations. Key Highlights Over 1,100 USMLE®-style multiple choice questions and detailed explanations, classified by organ system and difficulty Questions begin with a clinical vignette and approximately 20% are image-based, mirroring the USMLE®-format This essential resource will help you assess your knowledge and fully prepare for board examinations.Table of Contents1 Cell Injury, Adaptations, and Death 2 Inflammation and Repair 3 Hemodynamics 4 Diseases of the Immune System 5 Neoplasia 6 Genetic and Pediatric Diseases 7 Environmental and Nutritional Diseases 8 Diseases of the Cardiovascular System 9 Diseases of the Hematopoietic and Lymphoid Systems 10 Diseases of the Respiratory System 11 Diseases of the Kidney and Urinary Tract 12 Diseases of the Mouth and Gastrointestinal Tract 13 Diseases of the Liver, Gallbladder, and Biliary Tract 14 Diseases of the Pancreas 15 Diseases of the Male and Female Genital Tract 16 Diseases of the Breast 17 Diseases of the Endocrine System 18 Diseases of the Musculoskeltal System 19 Diseases of the Peripheral and Central Nervous Systems 20 Diseases of the Skin 21 Mixed Items 22 Images
£29.55
John Wiley & Sons Inc Pathologies of Speech and Language: Advances in
Book SynopsisThis volume gives a kaleidoscopic view on the field of clinical phonetics and linguistics. Topics include phonological issues in normal and defective development; aphasia, dysphasia, dysarthria, apraxia of speech and neurological conditions as well as critical evaluations of methods in clinical linguistics and phonetics.Table of ContentsList of Contributors. Preface. Acknowledgements. Part I: Phonology and Developmental Disorders. Chapter 1 The status of phonological representation in fluetn aphasia, S Kohn. Chapter 2 Sonority, glottals, and the characterization of (sonorant), B Heselwood. Chapter 3 Constraint-based analysis of Japanese rhotacism, I. Ueda, S. Davis. Chapter 4 Feature geometry, underspecification and child substitutions, M. Yavas, C.Core. Chapter 5 Identification and discrimination of vowels in children with apraxic speech disorders, P. Groenne, B. Maassen, Th. Crul. Chapter 6 Evaluation of speech perception and comprehension processes of children: Description and practical results, M. Gosy. Chapter 7 The influence of sampling context upon young children's production of fricative CV and CCV syllables, C. Miller, T. Spickler, R. Daniloff, R. Berry. Chapter 8 The development of between-words processes in the connected speech of children aged between 3 and 7 years, C. Newton, B. Wells. Chapter 9 Syntax at late stages of acquisition: Experiments with normal and SLI children, J. Niemi, . Hagg. Chapter 10 A follow-up study of the linguistic and intellectual abilities of children who were phonologically disordered, Th. Powell, M. Elbert, D. Dinnsen. Chapter 11 Language performance of black children as a function of their cultural mistrust, face of saminer, nature of reinforcement and language task, S. Terrell, R. Daniloff, M. Henoch, T. Flowers. Chapter 12 Stuttering as a honological encoding defect? R. Burger, F. Wijnen. Chapter 13 Perceptual properties of truncated infact protosyllabic CV - utterances, N. Roussel, R. Daniloff, M. Daly, K. Kao, C. Miller, R. Berry. Part II: Hearing Impairment and Capd. Chapter 14 Biology of speech sound perception and linguistic experience, N. Kraus, Th. McGee, D Burton Koch. Chapter 15 Sensorineural hearing loss as a filter in word comprehension, V. Mildner. Chapter 16 Speech perception tests on the internet: An example using filtering to simulate reception in hearing impairment, P. Korkko, K. Huttunen, M. Sorrri. Chapter 17 Validation of a central auditory speech perception test for children, K. Neijenhuis, Th. Crul, B. Maassen, P. Groenen. Chapter 18 Electrophysiological event-related indicators of speech perception performance in children using a cochlear implant, P. Groenen, A. Snik, P. van den Broek. Chapter 19 Listener judgements of diphthongs by hearing and deaf speakers, E. Gerrits, B. Elsendoorn, W. Peeters. Chapter 20 Durationsd and formants frequencies of diphthongs by hearing and deaf speakers, B. Elsendoorn, E. Gerrits, W. Peeters. Chapter 21 Evaluation of vocal production and hearing abilities of 1-2 year-old children. Criteria for an early cochlear implantation, M. Holm, S. Frischmuth, S. Vinter. Chapter 22 Interactive developmental intonology: Analysis of hearing mother-deaf children conversations, S. Vinter, C. Bried, M. Holm. Part III: Aphasia and Neurological Condition. Chapter 23 Single or dual semantics? Brain lateralization and the semantic processing of words, Y. Joanette, P. Goulet, L. Gagnon, B. LeBlanc, A. Simard. Chapter 24 Case assignment in agrammatis: Analysis of the spontaneous speech of Dutch and German agrammatic aphasics, E. Ruigendijk, R. Bastiaanse, R. van Zonneveld. Chapter 25 Production and perception of speech prosody in left- and right-brain-damaged adults, D. Huot, J. Ryalls, G. LeDorze. Chapter 26 An acoustic investigation of pitch accent contrasts in the speech of a Norwegian patient with a left hemisphere lesion (Broca's Aphasia), I. Moen, K. Sundet. Chapter 27 Assessment of auditory word comprehension in aphasia, W. Ziegler, A. Jochmann, A. Zierdt. Chapter 28 Remediation of apraxia of speech using magnetometer-feedback therapy, W. Katz, S. Bharadwaj. Chapter 29 Palilalia in progressive supranuclear palsy: Failure of the articulatory buffer and subcortical inhibitory systems, H. Garratt, K. Bryan, J. Maxim. Chapter 30 Acoustic analysis of coarticulation in cerebellar dysarthria, I. Hertrich, H. Ackermann. Part IV: Methods in Clinical Linguistics. Chapter 31 What hte neurologist can contribute to diagnosis and therapy in speech pathology, W. Renier. Chapter 32 Clinical computational copus linguistics: A case study, M. Perkins, R. Catizone, I. Peers, Y. Wilts. Chapter 33 exIPA transcriptions of consonants and vowels spoken by dyspractic children: Agreement and validity, W. Vieregge, B. Maassen. Chapter 34 Isochronicity in speech production and the perception of categorical timing relations, V. Boucher. Chapter 35 Effects of stricture-force changes on the coordination of oral and flottal aperture motions in normal speech, V. Boucher. Chapter 36 Articulation difficulties following maxillofacial surgery: A single case study, A. Main, S. Kelly, G. Manley. Chapter 37 CLEFTNET Scotland: Applications of new technology to the investigation and treatment of speech disorders associated with cleft palate within a Scottish context, M. Nairn, W. Hardcast, F. Gibbon, R. Razzell, L. Crampin, L. Harvey, B. Reynolds. Chapter 38 MoDiaS - A PC-based system for routine acoustic analysis of neurogenic speech disorders, M. Merck, W. Ziegler. Chapter 39 A comparison of computerized speech/voice anlaysis programs, S. Awan, T. Bressman, R. Sader, H. Horch. Chapter 40 Measures of RMS nasalance using NasalView in patients undergoing secondary osteoplasty, S. Awan, T. Bressman, R. Sader, H. Horch. Chapter 41 Does the syllable affliation of intervocalic consonantsd have an articulatory basis? Evidence from electromagnetic midsagittal artculography, N. Schiller, P. van Lieshout, A. Meyer, W. Levelt. Chapter 42 Registration of lip and tongue movement with a new electromagnetic articulography instrument, H. Horn, Th. Scholl, H. Ackermann, I. Hertrich, R. Berndt, G.Goz. Chapter 43 Variability of tongue-movement during speaking sequences in diagnosis of tongue-thrust, H. Horn, G. Goz, M. Bacher, J. Luther, D. Axman-Krcmar. Chapter 44 Variability of tongue movement during normal swallowing and tongue-thrust, H. Horn, G. Goz, M. Bacher, J. Luther, D. Axmann0Krcmar. Index.
£144.85
American Registry of Pathology Tumors of the Lymph Nodes and Spleen
Book SynopsisThe understanding of diagnostic lymph node and spleen pathology has evolved at an impressive pace since 1995, when the third series AFIP atlas was published. Progress has been fuelled, in large part, by the application of a number of technologies to the study of hematopoietic neoplasms. The World Health Organization (WHO) classification scheme for hematologic neoplasms has captured much of this progress, and is generally accepted for clinical practice. The current volume, part of the fourth series of atlases, integrates the WHO classification, including the 2016 revision, and highlights areas in which the WHO classification is likely to evolve with time. In keeping with the goals and tradition of the atlases, this volume emphasizes morphological features of hematopoietic neoplasms, and includes a discussion of differential diagnoses for each disease category. In addition, the results of immunophenotypic and molecular genetic testing for each disease are highlighted, including findings generated by using high-throughput techniques that likely will be integrated into standard diagnostics in the near future. Overall, this atlas will provide readers with the comprehensive information necessary for the pathological and clinical assessment of lymph node and splenic lesions.
£197.60
American Registry of Pathology Tumors of the Intestines
Book SynopsisThere have been many advances in the pathology of intestinal tumours since the publication of the Third Series Intestines Fascicle in 2003, but many of the foundations of intestinal tumour diagnosis remain tried and true. Tubular adenomas are still tubular adenomas, but better understanding of serrated polyps has been a key advance in the years since the publication of the Third Series volume. Additionally, developments in molecular biology of colorectal carcinoma have allowed for targeted therapy and refinements to our evaluation of Lynch syndrome, which was termed hereditary nonpolyposis colorectal carcinoma (HNPCC) in the past.Our understanding of other polyposis syndromes has similarly blossomed in the past 15 years. Neuroendocrine tumours have been reclassified in the 2010 World Health Organization classification of gastrointestinal tumours. The molecular basis of gastrointestinal stromal tumours of the intestines has been a subject of great interest as well.In producing this update, this group of authors has enjoyed working together in gathering images and information to update this edition of the Intestines atlas. In doing so, we stand on the shoulders of giants before us, namely Drs. Robert H. Riddell, Robert E. Petras, Geraint T. Williams, and Leslie H. Sobin.While many areas of intestinal tumour pathology are without controversy, the classification and nomenclature for appendiceal tumours remain a subject of debate, including among ourselves. We have attempted to offer information on the various divergent viewpoints where they exist for this topic and others. Our efforts have been synergistic, and we hope that readers will enjoy the many interesting illustrations that we were able to amass.
£157.60
American Registry of Pathology Melanocytic Tumors of Skin
Book Synopsis
£178.50
American Registry of Pathology Tumors of the Lower Respiratory Tract
Book SynopsisRemarkable advances have occurred since the Series 3 Fascicle published in 1995 with paradigm shifts in every dimension of our understanding of lung tumors including clinical, radiologic, histopathologic, cytopathologic, immunohistochemical, molecular and therapeutic aspects. The molecular revolution leading to effective targeted therapies and breakthroughs in immunotherapy for lung cancer have led to novel approaches incorporating the concept of personalized medicine for patients who historically had little hope. These advances have strengthened the place of pathologists to play a central role in the multidisciplinary team that is now needed to properly diagnose and manage lung cancer patients.
£186.40
American Registry of Pathology Tumors of the Salivary Glands
Book SynopsisThis book serves as a one-stop, comprehensive reference for the pathology of salivary gland neoplasms, with an emphasis on numerous high-quality, illustrative photomicrographs. The authors incorporated the most cutting-edge genetic data emerging on such tumors, as this information often has a profound impact on their diagnosis and classification. With the quickly evolving nature of salivary gland pathology, this contribution to the Fifth Series is a key update to the previous edition from the Fourth Series, which was published in 2008.
£999.99
Springer Nature Switzerland AG Color Atlas of Human Fetal and Neonatal Histology
Book SynopsisThe first edition of Color Atlas of Fetal and Neonatal Histology was an important step in updating the histology texts available to practicing pathologists and pathology trainees who perform fetal autopsy and/or participate in research involving fetal tissues. It was a well-received volume that filled a major gap in pathology references related to normal histology and provided a comprehensive, state-of-the art review of fetal and neonatal histology. While the basics of fetal histology have changed little in the intervening years since publication of the first edition, this successor edition provides new insights and a fresh perspective.This book contains six new chapters including: blood vessels and lymphatics, external genitalia, eye, ear, skin, and maceration changes. Many existing chapters have also been expanded to address a greater breadth of fetal and neonatal histology such as postnatal testis development and the cardiac conduction system. The “Special Considerations” sections were also expanded in many chapters to address particularly problematic issues within individual organ systems. The book reviews the histology of the major organ systems in the fetus and neonate and provides detailed images, up-to-date references, and practical guidelines for identifying tissues across all gestational ages of development. The second edition of Color Atlas of Fetal and Neonatal Histology serves as the ultimate go-to resource for pathologists and researchers dealing with, and interested in, fetal and neonatal histology. It provides a comprehensive summary of the current status of the field with excellent and extensive illustrative examples that help guide the clinical study of fetal and neonatal histology and stimulate investigative efforts with fetal tissue. Table of ContentsHeart.- Blood Vessels and Lymphatic Vessels.- Lung.- Gastrointestinal Tract.- Liver.- Pancreas.- Salivary Glands.- Kidney.- Urinary Bladder.- Testis.- Epididymis.- Vas Deferens.- Seminal Vesicle.- Prostate Gland.- Ovary.- Fallopian Tubes.- Uterus.- Vagina.- External Genitalia.- Adrenal Gland.- Thyroid Gland.- Parathyroid Gland.- Pituitary Gland.- Thymus Gland.- Spleen.- Lymph Nodes.- Palatine Tonsil.- Bone Marrow.- Brain and Spinal Cord.- Eye.- Ear.- Bone.- Skeletal Muscle.- Skin.- Mammary Gland.- Placenta.- Histological Changes Associated With Fetal Maceration.
£999.99
Springer Nature Switzerland AG Cardiac Pathology: A Guide to Current Practice
Book SynopsisThis updated second edition provides a comprehensive overview of cardiac pathology. Clear illustrations of the common styles of dissection are provided along with the normal anatomy and histology. The chapters cover autopsy heart examination, ischemic heart disease, myocarditis, sudden death, valvular disease, transplant pathology, cardiomyopathy, cardiac neoplasia and congenital heart disease with a clear analysis of diagnostic criteria (macroscopic, microscopic and genetic) for both common cardiac diseases and those of less common types. The text is accompanied by high quality macroscopic and microscopic images and references to other specialty data sources. Cardiac Pathology: A Guide to Current Practice is aimed at established pathologists and trainees, as well as any clinician with an interest in cardiac disease. It will be of value to those working in cardiac surgery, cardiology and those in the autopsy/forensic fields.Table of Contents
£113.99
Springer Nature Switzerland AG The International Academy of Cytology Yokohama
Book SynopsisThis text describes a system of reporting breast fine needle aspiration biopsy that uses five clearly defined categories, each described by a specific term and each with a specific risk of malignancy. The five categories are insufficient/inadequate, benign, atypical, suspicious of malignancy and malignant. Each category has a risk of malignancy and is linked to management recommendations, which include several options because it is recognized that diagnostic infrastructure, such as the availability of core needle biopsy and ultrasound guidance, vary between developed and low and middle income countries. This text includes key diagnostic cytological criteria for each of the many lesions and tumors found in the breast. The cytopathology of specific lesions is illustrated with high quality photomicrographs with clear figure descriptions. Chapters also discuss current and potential future ancillary tests, liquid based cytology, nipple cytology and management. An additional chapter provides an overview of an approach to the diagnosis of direct smears of breast fine needle aspiration biopsies.The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology provides a clear logical approach to the diagnosis and categorization of breast lesions by FNAB cytology, and aims to facilitate communication with breast clinicians, further research into breast cytopathology and related molecular pathology, and improve patient care. Table of ContentsThe International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology. Introduction and Overview.- Insufficient/Inadequate.- Benign.- Atypical.- Suspicious of Malignancy.- Malignant.- An Approach to the Interpretation of Breast Fine Needle Aspiration Biopsy Cytology Direct Smears.- Nipple Cytology.- Role of Ancillary Tests in Breast Fine Needle Aspiration Biopsy Cytology.- Fine Needle Aspiration Biopsy Cytology of the Breast Utilizing Liquid-based Preparations.- Clinical Management.
£61.74
Springer Nature Switzerland AG Clinical Forensic Medicine: A Physician's Guide
Book SynopsisThis updated volume on clinical forensic medicine covers the topics required for forensic healthcare professionals working in general forensic medicine and sexual offence medicine. All chapters have been reviewed and revised to reflect how the provision of forensic medical services has changed since the previous edition with multidisciplinary teams working in the custodial environment, comprising doctors, nurses, and paramedics and those practitioners providing sexual offence examinations.New and updated topics include: the increasing importance of photo documentation by health care professionals; updated information on strangulation, torture; a review of bite mark injuries; the explosion of Novel Psychoactive Substances worldwide; the changing patterns of deaths in custody and deaths following police contact; and the introduction in various jurisdictions of legal limits for drugs based on zero tolerance or a risk based approach.Written by a team of experts, the new edition of this book is a valuable resource for forensic healthcare professionals including doctors, nurses and paramedics working in general forensic medicine and sexual offence medicine, as well as emergency physicians, pediatricians and gynaecologists.Table of ContentsThe History & Development of Clinical Forensic Medicine World-wide.- Fundamental Principles.- Sexual Assault Examination.- Injury Assessment, Documentation & Interpretation.- Physical Child Abuse.- Chemical Crowd Control Agents.- Medical TASER Conducted Electrical Weapons.- Care of Detainees.- Infectious Diseases: The Role of the Forensic Physician.- Fitness to be interviewed.- Substance Misuse.- Deaths in Custody.- Traffic Medicine.
£94.99
Springer Nature Switzerland AG The Pathophysiologic Basis of Nuclear Medicine
Book SynopsisThis book, now in its fourth edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging. The new edition has been revised and updated significantly to reflect recent changes and to ensure that the contents are in line with likely future directions. In addition to that, chapters have been reorganized in order to simplify the contents and to increase the readability. The book starts by providing essential information on general pathophysiology, cell biology and biologic effects of ionizing radiation followed by the mechanisms of radiopharmaceutical localization in different tissues and cells. This is followed by a series of chapters that covers all relevant organ systems presenting the basic knowledge of anatomy, physiology, and pathology and relating them to the clinical utilization of various scintigraphic modalities. The final chapter is devoted to the basis of therapeutic applications of nuclear medicine. The book will prove invaluable to all with an interest in the pathophysiologic basis of Nuclear Medicine, including nuclear medicine professionals, radiologists, surgeons, pediatricians and internal medicine physicians.Table of ContentsChapter 1 : General concepts of Pathophysiology Chapter 2 : Cell biology and biologic effects of ionizing radiation Chapter 3 : Basis of Radiopharmaceutical uptake Chapter 4 : Basis of inflammation imaging Chapter 5 : Basis of Musculoskeletal imaging Chapter 6 : Basis of endocrine system imaging Chapter 7 : Basis of Genitourinary system imaging Chapter 8 : Basis of respiratory system imaging Chapter 9 : Basis of cardiovascular system imaging Chapter 10 : Basis of digestive system imaging Chapter 11 : Basis of CNS imaging Chapter 12 : Basis of oncologic imaging Chapter 13 : Basis of therapeutic radionuclide therapy
£170.99
Springer International Publishing AG Nasal Physiology and Pathophysiology of Nasal
Book SynopsisThis fully revised and expanded second edition provides a comprehensive and up-to-date overview of nasal physiology and pathophysiology. With the help of numerous tables, schematic drawings, and color photographs, it helps readers gain a better understanding of the impact of structural changes and the process of disease development, and to make treatment decisions. Each chapter has been written by a leading expert in the field and addresses one important aspect in an accessible way. Covering all four functions of the nose: respiration, defense, olfaction and cosmesis, the book discusses the various techniques for the clinical evaluation of nasal function as well as current trends and future directions in nasal physiologic research. This second edition also includes additional chapters on rhinomanometry, local nasal inflammation, T cells and B cells, and artificial intelligence for the nose. Given its scope, the book is a valuable resource for both experienced otorhinolaryngologists and novices in the field.Table of Contents1. Mucus, Goblet Cell, Submucosal Gland2. Coagulation system and rhinosinusitis 3. Cilia, Ciliary Movement, and Mucociliary Transport4. Functional Defense Mechanisms of the Nasal respiratory Epithelium 5. Local Nasal Inflammation : T Cells and B cells6. Mast Cells7. Macrophage8. The Neutophil and Chronic Rhinosinusitis9. The role of EO 10. CRS and biologic therapies 11. Nasal NO 12. Physiology and Pathophysiology of Sneezing and Itching13. The Dry Nose14. Physiology of the Aging Nose and Geriatric Rhinitis15. Nutrition and the Upper Respiratory Tract16. Physiology of Lacrimal drainage17. Intranasal Trigeminal Perception18. Sinus Pain 19. Computational Fluid Dynamics of the Nasal Cavity 20. Physiology and Pathophysiology of Nasal Breathing 21. Function of the Turbinates22. The Nasal valves23. Nose and Sleep Breathing Disorders24. Pathophysiology of OSAS25. Rhinomanometry26. Acoustic Rhinomanometry27. New Measurement methods in the Diagnosis of nasal Obstruction28. Testing of Transport, Measurement of Ciliary Activity29. Nasal Defensive Proteins30. Assessment of Olfactory Function 31. Olfaction32. Electron Microscopy and the Nose33. Genetic Background of the Rhinologic Diseases34. Vomeronasal Organ 35. Physiology of the Nasal Cartilages and their importance to Rhinosurgery36. Physiology and Pathophysiology of the Growing Skeleton 37. Physiologic Concerns During Rhinplasty38. Nasal Pulmonary Interactions39. Phyiologic and Dentofacial Effects 40. The nose and the Eustachian Tube41. Nanomedicine and nose
£170.99
Springer International Publishing AG Clinical Laboratory Management
Book SynopsisClinical Laboratory Management shall be a valuable resource for clinical laboratorians, students of medical laboratory technology, laboratory managers, and hospital managers.
£107.99
Springer Atlas of Interstitial Lung Disease Pathology
Book SynopsisGeneral Approach to Interstitial Lung Disease: Clinical, Radiologic, and Pathologic Considerations.- Imaging in Interstitial Lung Disease.- Biopsy Choices and Handling in Interstitial Lung Disease.- Acute Interstitial Pneumonia (AIP).- Organizing Pneumonia (OP).- Usual Interstitial Pneumonia (UIP).- Nonspecific Interstitial Pneumonia (NSIP).- Respiratory Bronchiolitis with Interstitial Lung Disease (RBILD), Smoking-Related Interstitial Fibrosis (SRIF), and Desquamative Interstitial Pneumonia (DIP).- Combined Pulmonary Fibrosis with Emphysema.- Langerhans Cell Histiocytosis.- Introduction to Granulomatous Forms of Interstitial Lung Disease.- Hypersensitivity Pneumonitis.- Sarcoid.- Miscellaneous Granulomatous Forms of Interstitial Lung Disease.- Eosinophilic Pneumonias.- Pulmonary Alveolar Proteinosis.- Lymphangioleiomyomatosis.- Drug Reactions Producing Interstitial Lung Disease.- Lymphoid and Hematopoietic Processes Producing a Pattern of Interstitial Lung Disease.- Bronchiolitis.- Interstitial Lung Disease in Patients with Connective tissue Diseases and Interstitial Pneumonias with Autoimmune Features.- Pneumoconioses Producing a Pattern of Interstitial Lung Disease.- Mimics of Interstitial Lung Disease.
£999.99
Springer PathoMaps
Book SynopsisGeneral pathology.- Respiratory tract.- Vascular and lymphatic system.- Heart.- Ear, nose and throat.- Esophagus and stomach.- Small and large intestine.- Liver and intrahepatic bile ducts.- Gallbladder, extrahepatic bile ducts and pancreas.- Kidneys.- Male reproductive system and urinary tract.- Female reproductive system.- Breast and pregnancy-associated diseases.- Soft tissues.- Joints.- Bones.- Skin.- Primary lymphatic organs (bone marrow and thymus).- Secondary lymphatic organs (Lymph nodes and spleen).- Pituitary and adrenal gland.- Thyroid and parathyroid glands.- Central Nervous system (CNS).- Peripheral nervous system and musculature.- Eye.- Hereditary tumor syndromes and phacomatoses.- Service section.
£28.49
De Gruyter Late Radiation Pathology of Mammals
Book Synopsis
£111.62
Thieme Publishing Group Oral Pathology
Book SynopsisA key tool in recognizing and diagnosing lesions of the oral cavity and face at the earliest possible stage. Peter A. Reichart, DDS, Professor, Center for Dentistry, Charite Clinic, Berlin, Germany; and Hans Peter Philipsen, DDS, Professor, San Pedro de Alcantara, Spain This newest volume in Thieme's world-acclaimed Color Atlas of Dental Medicine Series forges the crucial connection between clinical oral pathology and histopathologic examination to arrive at a precise and definitive diagnosis. You will find more than 1,000 exquisite, full-color illustrations that cover the spectrum of clinical, radiographic, and histopathologic findings. And in a unique benefit, the book follows the sequential steps of a typical clinical examination, offering you the practical approach you can most easily use. Special features: Offers a new understanding of the pathogenesis and etiology of oral lesions, with magnificent full-color photographs and illustrations Chapters organized by the anatomic configuration of the oral region that you would follow in a standard examination Covers dozens of diseases of the oral mucosa and face; TMJ disorders and diseases of the salivary glands; cancer and organ transplant-related syndromes; diagnosis and treatment of facial pain; and psychosomatic oral diseases Includes a dedicated chapter on the oral manifestations of HIV infection Complete with "diagnostic keys", a tabular section organized by color, surface structure and radiographic criteria of a wide range of oral lesions, the book is indispensable for establishing an "at-a-glance diagnosis" when you have a patient seeking immediate guidance. This book offers no less than a wholly new concept in the practice of dentistry today: a synthesis of clinical practice and oral pathology that puts dentists ever closer to clinical medicine. It allows you to recognize and diagnose lesions of the oral cavity and face at the earlier possible stage, and know when referral is required. Take advantage of the experience and knowledge of the two world-renowned authors and move your practice to a new level: order Oral Pathology today! (Color Atlas of Dental Medicine, Series Editors: Klaus H. Rateitschak, DDS, PhD, and Herbert E. Wolf, DDS)Trade ReviewAn exhaustive atlas of oral pathology..the text is clear and concise..an invaluable and friendly resource for the practicing physician or resident in training. -- Journal of the Osteopathic College of Ophthalmology and Otorhinolaryngology ". . . beautifully developed . . . a wonderful balance between illustrations and text, allowing for easy reading and comprehension . . . will certainly assist all dental clinicians in gaining a more complete understanding of the etiology, diagnosis, and treatment of craniomandibular disorders." -- Journal of Clinical OrthodonticsTable of ContentsOral Diagnosis Biopsy HIV Infection Facial Region Lips Buccal Mucosa/Sulcus Tongue Floor of the Mouth Palate Gingiva Edentulous Jaw Jaws Epithelial Cysts of the Jaws Odontogenic Tumors Salivary Glands
£170.52
Thieme Publishing Group Practical Breast Pathology
Book SynopsisAll the information needed for successful diagnosis and management of breast carcinoma Focused on a modern, interdisciplinary approach to diagnosing and managing diseases of the breast, this concise book builds on the high standard set in the previous edition. It provides a complete foundation in the basic principles, radiologic appearance and underlying pathology of breast disease, without overwhelming non-pathologist members of the team with excessive detail. For effective communication at every level, Practical Breast Pathology, Second Edition provides the clear information, case examples and superb illustrations that make it an ideal clinical problem solver. Special features of the second edition: High-quality examples of modern multimodality radiology (digital mammography, ultrasound and magnetic resonance imaging) correlated with large-format 2D and 3D histologic slides New findings on such clinically important topics as the lobar nature of breast carcinoma, multifocality, diffuse carcinomas and extent of disease, concept of the sick lobe and more Introduction of the molecular classification of invasive breast cancer Discussion of prognostic and predictive factors in breast carcinoma, such as hormone receptors and HER2 status Updates on preoperative diagnosis, including intact biopsy and radiologic assessment of the extent and distribution of lesions Enriched with new information and stunning illustrations in every chapter, Practical Breast Pathology, Second Edition is a key link in the exchange between pathologists, radiologists, oncologists and breast surgeons, as well as residents and trainees. It provides an essential framework for understanding the mammographic-pathologic correlation, leading to increased cooperation among clinical team members and significantly improved outcomes for patients.Table of Contents1. Normal Breast Tissue or Fibrocystic Change? 2. General Morphology of Breast Lesions 3. Hyperplastic Changes with and without Atypia 4. Ductal Carcinoma In Situ 5. The Most Common Types of Invasive Breast Carcinoma 6. The Most Common Benign Lesions and their Borderline and Malignant Counterparts 7. Fine-Needle Aspiration or Core Biopsy: A Preoperative Diagnostic Algorithm 8. The Postoperative Workup 9. Assessment of the Most Important Prognostic Parameters 10. Case Reports
£97.38
Thieme Publishing Group Freyschmidt's Koehler/Zimmer Borderlands of
Book SynopsisThe classic text in a revised and expanded fifth edition! Is a radiological finding normal or pathologic? This "borderline" between the two states presents a daunting challenge to radiologists and orthopedic surgeons on a daily basis. Thieme proudly presents the updated and expanded fifth edition of the landmark text generations of physicians have used to differentiate borderline findings! Redesigned for optimal use, the book is organized according to diagnostic questions raised by clinical findings, radiographic findings, or both. You'll find all possible variants in five pathologic categories: anomaly; trauma; necrosis; inflammation; and tumor. The book provides imaging examples of the entire body, from the skull base, shoulder, and clavicle, to lower spine, knees, and the feet. More than 4,200 high-quality illustrations give clear examples of potential findings. Key features of this historic text: Illustrated with more than 4,200 outstanding drawings, photographs, and radiographs--nearly 4 per page! Full coverage of pathologic conditions in their fully developed form, Exhaustive analysis of borderline findings for both pediatric and adult cases Valuable guidelines on integrating pathologic conditions with CT and MRI findings This book is the encyclopedic resource that will expand your knowledge of findings in skeletal radiology and enhance your diagnostic skills. No personal or professional library is complete without this new standard-bearer in the field!Table of Contents1 Introduction to the Radiological Evaluation of Normal Variants 2 Upper Extremity The Hand Forearm Elbow Region Upper Arm 3 Shoulder Girdle and Thorax Scapula Acromioclavicular Joint The Shoulder Joint as a Whole Clavicle and Sternoclavicular Joint Sternum Ribs 4 Skull Cranial Vault Skull Base Facial Skeleton 5 Spinal Column Atlas and Axis Midcervical and Lower Cervical Spine Thoracic Spine Lumbar Spine Sacrum and Coccyx Sacroiliac Joints 6 Pelvis 7 Lower Extremity Femur Patella Proximal Tibia and Fibula Knee Joint as a Whole Shaft of the Tibia and Fibula Distal Tibia and Fibula Foot
£109.72
Springer International Publishing AG Laboratory Hemostasis: A Practical Guide for
Book SynopsisCoagulation testing is the basis for the diagnosis of bleeding and thrombotic disorders, as well as the mainstay of anticoagulant monitoring and management. This handbook provides practical information and guidance on topics relevant to directing a coagulation laboratory, filling a void in the literature. Since the first edition, all chapters have been updated and an entirely new chapter is included on pharmacogenomics and pharmacogenetics. The book will aid pathologists, clinical laboratory scientists and other physicians serving as laboratory directors to understand and carry out their responsibilities. It will also assist residents and fellows in learning the basics of coagulation testing and serve as a useful day-to-day reference for coagulation laboratory supervisors, technologists, and technicians. Finally, clinicians may find aspects of the book helpful in understanding the role of the coagulation laboratory in patient evaluation and monitoring.Trade ReviewFrom the book reviews:“The purpose is to provide a single reference with information and guidance related to directing a clinical coagulation laboratory. The book is intended for everyone involved in clinical coagulation testing -- residents and fellows, clinical laboratory scientists, pathologists, or doctoral level scientists involved in directing a clinical coagulation laboratory. It would also be of interest to ‘users’ -- e.g., clinical hematology consultants. … This is a must-have for any clinical coagulation laboratory director.” (Valerie L. Ng, Doody’s Book Reviews, January, 2015)Table of ContentsRole and Responsibilities of the Laboratory Director.- Collection of Coagulation Specimens.- Instrumentation for the Coagulation Laboratory.- Validation of Coagulation Assays, Instruments and Reagents.- Hemostasis Screening Assays.- Testing for Inherited Bleeding Disorders.- Testing for Acquired Platelet Disorders.- Acquired Coagulation Disorders and TTP.- Testing for Inherited and Acquired Thrombotic Disorders.- Monitoring of Anticoagulant Therapy.- Pharmacogenomics and Pharmacogenetics.- Coagulation Testing and Transfusion Medicine.
£75.99
Springer International Publishing AG Atlas of Salivary Gland Pathology
Book SynopsisSurgical pathologists play a central role in patient surveillance and treatment by surgeons, radiation oncologists, and medical oncologists. Although salivary gland tumors are uncommon overall, their histopathologic diversity and challenge command the attention of practicing surgical pathologists. Atlas of Salivary Gland Pathology focuses on the diagnostic approach to salivary gland neoplasia—one of the more challenging fields within surgical pathology—emphasizing the need to understand downstream implications with respect to patient surveillance and treatment. The presence of formidable histologic mimicry in salivary gland neoplasia is well-documented in the pathology literature and has also been observed in the consultation practice of the volume editor. This textbook is designed with the needs of practicing surgical pathologists and pathologists-in-training in mind, providing a comprehensive overview of both common and rare salivary gland neoplasms. The primary educational objectives for readers include the following: 1) distinguish benign from low-grade malignant salivary gland neoplasms, 2) effectively use histochemical, immunohistochemical, and cytogenetic studies in challenging cases, 3) understand which diagnoses merit additional surgery and/or adjuvant therapy (radiation, chemotherapy), and 4) enhance pathologist-to-clinician communication in the setting of salivary gland disease.Table of ContentsGross Anatomy.- Microscopic Anatomy.- Intraoperative Examination.- Gross Examination.- Microscopic Examination.- Acinic Cell Carcinoma.- Adenoid Cystic Carcinoma.- Basal Cell Adenoma.- Basal Cell Adenocarcinoma.- Canalicular Adenoma.- Carcinosarcoma.- Clear Cell Carcinoma.- Epithelial-Myoepithelial Carcinoma.- Intraductal Carcinoma.- Lymphadenoma.- Lymphoepithelial Carcinoma.- Mucoepidermoid Carcinoma.- Myoepithelioma.- Myoepithelial Carcinoma.- Oncocytoma.- Oncocytic Carcinoma.- Pleomorphic Adenoma.- Pleomorphic Adenoma, Carcinoma Ex.- Polymorphous Adenocarcinoma.- Salivary Duct Carcinoma.- Secretory Carcinoma.- Small Cell Neuroendocrine Carcinoma.- Warthin’s Tumor.
£113.99
Springer International Publishing AG Non-Neoplastic Liver Pathology: A Pathologist’s
Book SynopsisThis book provides a quick, pattern-based reference for interpreting histologic changes in non-neoplastic liver. It is designed to guide the reader based on morphologic pattern and basic clinical information. Each chapter covers a broad but identifiable pattern of pathologic liver findings (e.g., “portal inflammation” or “steatosis”) and discusses the major disease entities that manifest as such a pattern. As liver biopsies can be complex and daunting, such an approach should improve the reader’s ability to identify a likely diagnosis or differential and to distinguish among the possible disease entities. Sample reports at the end of each chapter offer guidance on how to sign out cases. Non-Neoplastic Liver Pathology: A Pathologist’s Survival Guide will be of value to practicing pathologists without specialized training in hepatic pathology, pathology residents and fellows trying to learn the basics of non-neoplastic liver pathology, and hepatologists interested in reviewing liver biopsies with pathologistsTrade Review“This relatively slim book is envisioned as a quick, pattern‐based guide for interpreting liver biopsies. … This book is intended primarily for general pathologists who have had limited training in hepatic pathology. … Pathologists will be better served by this book … .” (Ivan Damjanov, Doody's Book Reviews, February, 2017Table of Contents
£98.99
Springer International Publishing AG Atlas of Diffuse Lung Diseases: A
Book SynopsisThis atlas is designed as an easy-to-use reference guide that identifies and illustrates the key patterns of diffuse lung diseases observed on high-resolution computed tomography (HRCT) and then documents in more detail the characteristics and appearances of the individual diseases, grouped on the basis of their prevalent pattern. A further feature of the book is its interdisciplinary nature: contributions from experts in various specialties are tightly interwoven throughout and many pathologic correlations are included. Less experienced readers will find that this atlas, with its wealth of figures and helpful color coding, steers them towards correct interpretation when confronted by the multiplicity and complexity of these diseases; those who are already experts, on the other hand, will benefit from the detailed coverage of individual diseases, which will deepen their understanding. At the end of the book, a graphically appealing and practice-oriented illustrated glossary with tips and tricks offers a further highly effective educational tool. Given the clinical spectrum of diseases covered, this atlas will prove invaluable for a wide range of healthcare workers, especially radiologists, pulmonologists, and pathologists.Table of ContentsAnatomy.- Secondary Lobule.- Thinking through Pathology.- Elementary Lesions.- How to approach the Diseases.- Key HRCT Patterns.- Septal Pattern.- Fibrosing Pattern.- Nodular Pattern.- Alveolar Pattern.- Cystic Pattern.- Dark Lung Pattern.- Septal Diseases.- Fibrosing Diseases.- Nodular Diseases.- Alveolar Diseases.- Cystic Diseases.- Dark Lung Diseases.- Case-Based Glossary with Tips & Tricks.
£75.99
Springer International Publishing AG Atlas of Mohs and Frozen Section Cutaneous
Book SynopsisOf all the techniques used to treat non melanoma skin cancer, the highest cure rates belong to the Mohs surgical procedure. Critical to this technique is optimal preparation and interpretation of frozen sections. The second edition of this highly successful atlas details both common and uncommon cutaneous neoplasms that can serve as a source of reference for established practitioners and a review for those in training. It includes new frozen section specimens, the most current diagnostic guidelines, and discussion of the advancements in tissue staining. There is also an additional chapter with self-study tools, where readers can test their knowledge using various images with a multiple choice answer format, followed by a discussion of the correct answer. With high resolution figures, the Atlas of Mohs and Frozen Section Cutaneous Pathology, Second Edition is the premier text on the topic, serving as a highly practical guide to microscopic analysis, diagnosis, and discrimination of common and problematic cutaneous neoplasms. Highlights of the Atlas include diagnosis of basic and routine dermatologic entities, diagnosis and distinction of rare and/or deadly neoplasms such as dermatofibrosarcoma protuberans and merkel cell carcinoma, a troubleshooting guide dealing with quality control of the frozen section technique, and discussion of techniques including immunohistochemistry. Comprehensive and presented in full color, the Atlas of Mohs and Frozen Section Cutaneous Pathology, Second Edition is an indispensable reference for anyone involved with the Mohs procedure, including dermatologic surgeons, Mohs cutaneous surgeons, as well as pathologists and dermatopathologists who perform frozen section analysis of cutaneous specimens.Table of ContentsContentsSection I: Introduction1 Mohs and Frozen Section OverviewMichael B. Morgan, Terri Bowland2 Quality Assurance Dennis H. Nguyen, Daniel M. Siegel, Deborah Zell, Richard Spallone, Michael B. MorganSection II: Tumors of the Epidermis/Adnexae3 Histology with Regional and Ethnic Variation Michael B. Morgan, John R. Hamill, Jr.4 Benign Epidermal Tumors Michael B. Morgan5 Pseudotumors Martin Dunn, Michael B. Morgan6 Squamous Cell Carcinoma: Variants and Challenges Michael B. Morgan7 Basal Cell Carcinoma: Variants and Challenges Michael B. Morgan8 Adnexal Neoplasms Michael B. Morgan9 Malignant Adnexal Neoplasms Ryan S. Jawitz, Jack C. Jawitz, Michael B. Morgan10 Merkel Cell Carcinoma Michael B. Morgan11 Sebaceous Tumors Michael B. Morgan12 Paget’s Disease Michael B. Morgan13 Melanocyte Pathology Michael B. MorganSection III: Tumors of the Dermis14 Benign Mesenchymal Tumors Michael B. Morgan15 The Sarcomas Aaron M. Bruce, James M. Spencer16 Lymphoid Pathology John R. Hamill Jr., Michael B. MorganSection IV: Special Topics17 Perineural Pathology Martin Dunn, Michael B. Morgan18 Cytopathology of Cutaneous Tumors Kenneth B. Calder, Rahel Mathew, Michael B. Morgan19 Immunohistochemistry Applications Basil S. Cherpelis, L. Frank Glass, John R. Hamill Jr., Neil Alan Fenske20 Histotechnique and Staining Troubleshooting John R. Hamill Jr., Stephen SpencerSection V: Mohs Clinicopathologic Self-Test Series 21 A Painful Perineural Infiltrate Rebecca S. Thornhill, Tyler Scott22 A Painful Subcutaneous Nodule Rebecca S. Thornhill, Nicole Asher23 Basaloid LesionTyler Scott, Nicole Asher 24 Rapidly Growing Hemorrhagic PapuleRebecca S. Thornhill, Nicole Asher 25 Aggressive Spindle Cell NeoplasmRebecca S. Thornhill, Tyler Scott 26 Eyelid Tumor Nicole Asher, Tyler Scott27 Non-melanoma Skin Cancer with Anemia Rebecca S. Thornhill, Tyler Scott28 Follicular Neoplasm Tyler Scott, Nicole Asher29 Hemorrhagic Papule in a Patient with Lip Carcinoma Rebecca S. Thornhill, Tyler Scott30 Blue Ball in the DermisRebecca S. Thornhill, Nicole Asher
£142.49
Springer International Publishing AG Clinical Oral Medicine and Pathology
Book SynopsisFollowing on the favorable reception of the first edition, the authors have thoroughly revised and updated the second edition of this resourceful clinical handbook. The book has been well received internationally by a wide audience of clinicians, including general dentists, oral surgeons, otolaryngologists, primary care physicians, nurse practitioners, dental hygienists, physician assistants, and dermatologists, and sales have been strong among students and post-graduate residents training in medical, dental, and allied health fields, supporting the versatility of this work and serving as testimony to its value in both the academic and private practice arenas. Several key updates and improvements have been made to the second edition. All informational content has been updated to ensure accuracy and relevance, particularly in the rapidly evolving fields of oncology and pharmacology. A new chapter has been added entitled “Oral Sequelae of Cancer and Cancer Therapy” which better organizes and consolidates previous content while expanding on topics such as targeted therapies and hematopoietic stem cell transplantation. Additional clinical images have been included throughout the book so that the full clinical spectrum of any given condition is well-represented. Furthermore, the print quality, as well as the positioning and layout of the clinical images has been improved for optimal utility. Lastly, the summary boxes that follow each condition have been reconfigured with color-coded icons for improved definition, ease of use and cross-referencing. Clinical Oral Medicine and Pathology, Second Edition will continue to serve as an authoritative contemporary resource for clinicians seeking guidance in the diagnosis and management of oral diseases.Trade Review“The book is well structured with good flow from one chapter to the next. Each chapter is well laid-out with clear headings and illustrated text to help with diagnosis and management of oral medicine-related conditions. Concise descriptions of each condition provide background information and treatment recommendations with useful summary tables for quick reference. … this would be a useful resource for any healthcare professional seeing patients with oral disease.” (Anne M. Hegarty, British Journal of Hospital Medicine, Vol. 78 (1), January, 2017)Table of ContentsTable of Contents Chapter 1 Normal Anatomy Chapter 2 Variants of Normal and Common Benign Conditions Chapter 3 Diagnostic Tests and Studies Chapter 4 White Lesions Chapter 5 Immune-Mediated and Allergic Conditions Chapter 6 Pigmented Lesions Chapter 7 Oral Infections Chapter 8 Salivary Gland Disease Chapter 9 Oral Cancer Chapter 10 Orofacial Pain Conditions Chapter 11 Oral Manifestations of Systemic Disease Chapter 12 Oral Sequelae of Cancer Therapy Chapter 13 Prescribing Guidelines for Commonly Used Medicationsp>
£75.99
Springer International Publishing AG Inflammatory Dermatopathology: A Pathologist's
Book SynopsisThis fully updated and revised new edition will guide the reader to develop a systematic approach to the diagnosis of inflammatory disorders of the skin. It covers the most common and clinically important inflammatory disorders of the skin in a image-rich easy to read format. Each section includes a practical tips section to help navigate the differential diagnosis. Examples of diagnostic comments are provided that practicing pathologists can utilize in their own reports. Therefore, this book will not only guide the reader in how to approach inflammatory dermatoses, it will also help with writing the report. All chapters are revised and updated and include new images. The second edition of Inflammatory Dermatopathology will be of great value to surgical pathologists, pathology residents, dermatology residents, and dermatopathology fellows. Table of ContentsIntroduction.- Spongiotic Dermatitis.- Psoriasiform Dermatitis.- Interface Dermatitis.- Vasculitis and Thrombotic Disorders.- Nodular and Diffuse Dermatitis.- Palisading Granulomatous Dermatitis.- Sclerosing Dermatitis.- Bullous Dermatitis.- Panniculitis.- Alopecia.- Infections.- Miscellaneous Dermatoses.
£75.99
