Pathology Books

Book SynopsisThe Italian Study Group on Cardiomyopathies organized in Florence in April 1997, eight years after the first successful meeting, the second international symposium devoted to "Advances in Cardiomyopathies". In these years exceptional progress has been made in the field of heart muscle diseases, in clinical research as well as in molecular biology, molec- ular genetics., pathophysiology and treatment. Many of these advances were presented and discussed in Florence by a distinguished team of international experts. Hypertrophic cardiomyopathy was addressed in ten papers; in the first one Seidman reported the results obtained by the use of molecular genetic tech- niques which showed that hypertrophic cardiomyopathy is a heterogeneous disorder caused by different mutations of different genes and discussed the clinical role and significance of genetic testing. Original data regarding the natural history and prognosis of symptomatic patients were obtained in the Italian multicentric study (Cecchi, Lazzeroni), while Baroldi discussed the clinico-pathologic spectrum of the disease in severely symptomatic patients treated with heart transplantation. Sudden death in the young (Basso), the identification and management of high risk patients (Elliott), the clinical importance and the problems of detec- tion of ischemia (Camici) were deeply discussed as well as the indications and results of different types of treatment: medical, surgical, DDD pacing (Spirito, Betocchi, Schoendube).Table of ContentsIntroduction: II Florence Meeting on Advances in Cardiomyopathies The Clinical Significance of Genetic Testing in Familial Hypertrophic Cardiomyopathy The Italian Multicentric Study on Hypertrophic Cardiomyopathy: I.Natural History and Clinical Course of Unselected Patients Detection and Clinical Consequences of Myocardial Ischemia and, Reduced Coronary Reserve The Coronary Circulation is Dysfunctional in both Hypertrophied and Non-Hypertrophied Myocardium Hypertrophic Cardiomyopathy and Sudden Death in the Young: a Pathologist's View Identification and Management of High Risk Patients with Hypertrophic Cardiomyopathy The Italian Multicentric Study on Hypertrophic Cardiomyopathy: II. Prognostic Assessment in Symptomatic Patients Medical Treatment of Heart Failure in Hypertrophic Cardiomyopathy DDD Pacing in HCM: State of the Art Indications and Outcome of Cardiac Surgery for Severely Symptomatic Patients with Hypertrophic Obstructive Cardiomyopathy Genetic Basis of Dilated Cardiomyopathy Virus Infection in Cardiomyopathies: Brief Overview, Recent Advances Organ-specific Cardiac Autoantibodies in Dilated Cardiomyopathy: Pathogenetic Implications Inflammatory Cardiomyopathy: Diagnosis and Therapeutical Options Pathophysiologic Role of Coronary Microcirculatory Impairment in Dilated Cardiomyopathy Molecular Biology of Cardiac Failure Dilated Cardiomyopathy: does Etiological Heterogeneity Portend Clinical Heterogeneity? The Natural History of Dilated Cardiomyopathy. The SPIC Registry 1986-1995. Therapeutic Strategies in Dilated Cardiomyopathy: Immunosuppressive Treatment for Inflammatory Dilated Cardiomyopathy (Myocarditis) Prevention of Sudden Death in Patients with Dilated Cardiomyopathy End-Stage Heart Failure and Timing of Heart Transplantation Beta-Blockers for Heart Failure: Practical Issues DDD Pacing in Dilated Cardiomyopathy Cardiomyoplasty: Surgical Therapy for Ischemic and Idiopathic Dilated Cardiomyopathies .

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Book SynopsisThis new edition provides trainees with a comprehensive review of cytopathology, presented as multiple choice questions with answers and detailed explanatory notes. Divided into twelve chapters, the book covers different body systems including the respiratory tract, breast, thyroid, lymph nodes, liver, gastrointestinal tract, and much more. Each topic covers key aspects of modern cytopathology including diagnostic criteria, reporting systems, ancillary testing modalities, molecular mechanisms of diseases, and clinico-pathological correlations. All chapters have been fully updated and questions are in line with those trainees may encounter in American Board of Pathology examinations. Key learning points are summarised at the end of each topic. Authored by renowned pathologist Fang Fan from City of Hope Medical Centre, California, the third edition of this book is highly illustrated with clinical images and figures. The previous edition (9789352700462) published in 2017.Table of ContentsChapter 1: Cervical and Vaginal Cytology Chapter 2: Respiratory Tract and Mediastinum Chapter 3: Urine and Bladder Washings Chapter 4: Effusions and Peritoneal Washings Chapter 5: Cerebrospinal Fluid Chapter 6: Breast Chapter 7: Thyroid Chapter 8: Salivary Gland Chapter 9: Lymph Nodes Chapter 10: Liver Chapter 11: Gastrointestinal Tract, Pancreas and Biliary Tract Chapter 12: Laboratory Management, Quality Control and Quality Assurance

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Book SynopsisCrop diseases are known to be caused by various abiotic and biotic agents. Among the biotic agents, microbial plant pathogens u fungi, bacteria, phytoplasmas, viruses and viroids u accounts for significant quantitative and qualitative losses in agricultural and horticultural crops. It is essential to have adequate knowledge of various aspects of these plant pathogens. Information on precise identification of microbial plant pathogens, process of disease development, epidemiology, assessment of losses due to diseases, principles of disease management, their applications for containing the diseases and the possible ways of integrating the practices is required to develop and enhance the effectiveness of disease management systems suitable for different ecosystems. Basic plant pathological methods provided in the appendix and glossary of plant pathological terms presented in this book will help the students to have a clear understanding of the subject. Graduating students, researchers and teachers desirous of updating the information on different aspects of microbial plant pathogens and the diseases caused by them, will find this book to be useful.Table of ContentsPart I: Causes and Development of Crop Diseases: 1: Introduction 2: Types of Crop Diseases 3: Methods of Establishing the Causes and Diagnosis of Crop Diseases 4: Development of Plant Diseases Caused by Microbial Pathogens 5: Molecular Basis of Microbial Pathogenicity and Host Plant Defense 6: Assessment of Losses Caused by Crop Pathogens Part II: Principles of Crop Disease Management: 7: Principles and Practices of Crop Disease Management 8: Exclusion of Diseases Caused by Microbial Plant Pathogens 9: Reduction of Pathogen Inoculum Using Physical and Chemical Techniques 10: Reduction of Pathogen Inoculum Using Cultural Practices 11: Reduction of Pathogen Inoculum Using Antimicrobial Chemicals 12: Reduction of Pathogen Inoculum Using Biological Agents 13: Host Plant Resistance to Microbial Pathogens 14: Induction of Resistance to Crop Diseases Part III: Practices Adopted for Crop Disease Management: 15: Integrated Management of Diseases Affecting Roots of Plants 16: Integrated Management of Diseases Affecting Stems of Plants 17: Integrated Management of Diseases Affecting Foliage of Plants 18: Integrated Management of Diseases Affecting Inflorescence of Plants 19: Integrated Management of Viral and Phytoplasma Diseases of Crops 20: Integrated Management of Postharvest Diseases

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Book SynopsisTechniques related to various physiological phenomenon are subject of tremendous interest and importance to plant physiologist, agronomist, horticulturist, ecologist, and biochemists. This book is intended to provide recognized methods related various plant processes in a comprehensive form. Techniques on crop physiology such as hydroponics and plant nutrition, test for various stresses, water potential and water flow in plants, canopy gas measurements (Photosynthesis, Respiration and Transpiration), basic equations for growth studies and methods for estimations of plant products, microclimate. Efforts were also made to incorporate the topic like Climate Change and theory of phytotron as well as rhizotron in this book. The book will make the reader familiar with latest procedure to elucidate the problems. The validity of the results based on fundamentals principles of physics. This book is meant to be used in conjunction with a standard text of plant physiology though elementary principles relating to the techniques are briefed. The subjects on hormones, tissue culture and seed technology are useful for students. Hope this book shall serve the need of students, teachers and researchers.Table of Contents1. Importance of Plant / Crop Physiology in Agriculture 2. Plant Physiology Laboratory 3. Osmotic Pressure Potential by Plasmolytic Method 4. Separation of Plant Pigments by Chemical Method 5. Determination of Stomatal Frequency and Stomatal Index 6. Transpiration 7. Oxygen Evolution During Photochemical Reaction 8. Measurement of Photosynthetic Rates by Gas Exchange Techniques 9. Growth Regulators 10. Seed Physiology 11. Tissue Culture Techniques 12. Growth Analysis 13. Hydroponics and Plant Nutrition 14. Tests for Various Stresses in Crop Plants 15. Analysis for Carbohydrates 16. Nitrogen and Protein Analysis 17. Analytical Methods for Fats and Fatty Acids 18. Micronutrient Analysis 19. Determination of Phytochemicals 20. Climate Change, Phytotron and Rhizotron

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Book SynopsisThe book has been written as Text Book for Undergraduate as well as Post Graduate students covering major aspect of horticultural diseases.Table of Contents01 Diseases of fruit crops like mango, banana, grapes, citrus, guava, papaya, apple, custard apple, sapota. 02 Diseases of plantation Crops like coconut, coffee, tea, betelvine. 03 Diseases of vegetable crops like potato, tomato, brinjal, chilli, bhendi, crucifers, cucurbits, onion & garlic, pea, beans, ginger. 04 Diseases of flower crops like rose, chrysanthemum, jasmine and crossanda 05 Each has further be divided into sub-heads such as introduction and economic importance, symptoms on different parts, causal organism, disease cycle, favorable conditions 06 Symptoms of important diseases have been illustrated with coloured photographs which will help in their correct and easy diagnosis. 07 Management practices including, cultural, physical, biological, host resistance leading to integrated disease management. 08 Some portions have been slightly elaborated to suit the requirement of students appearing in ARS/NET/SRF competitive examinations. 09 this book will serve immensely for teachers and students in the field of plant pathology.

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Book SynopsisKeeping abreast of the major strides made in the field of neuropathology, Essentials of Diagnostic Surgical Neuropathology brings out its second edition with the aim of keeping the neuroscience community updated with the new developments in neuropathology. This second edition comes close on the heels of the fifth edition of the WHO Classification of Central Nervous System Tumours (WHO CNS5) which was published in 2021. This new edition has retained the concise, point wise format of the earlier edition, making it a handy reference book. While the major changes in this edition are in neoplastic pathology, this book also provides updates in the pathology of non-neoplastic lesions that need surgical intervention. The highlights of the neoplastic section are: Description of new tumour types and subtypes included in the WHO CNS5 Grading of tumours as per WHO CNS5 Relevant immune profile and diagnostic molecular pathology for each tumour according to WHO CNS5. Essential and desirable diagnostic criteria, as defined by WHO CNS5, in a tabular form at the end The salient features of the non-neoplastic section include: New section on Therapy-related Neuropathology Recent classifications of vascular malformations and epilepsy related lesions New section on Infectious and Inflammatory Lesions Mimicking Neoplasms New chapter on Surgical Pathology of Spinal Dysraphism and Other Neural Tube Defects Another important feature includes the addition of a new chapter on techniques viz. Smears in the Rapid Diagnosis of Central Nervous System Lesions Challenges in the Interpretation of Stereotactic Biopsies Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.Table of Contents1. Tumors of the Nervous System 2. Aneurysms and Vascular Malformations of the Nervous System 3. Traumatic Brain Injury 4. Surgical Pathology of Drug-Resistant Epilepsy 5. Infectious and Inflammatory Lesions Mimicking Neoplasms 6. Surgical Pathology of Spinal Dysraphism and Other Neural Tube Defects 7. Miscellaneous

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Book SynopsisEarly diagnosis of parasitic diseases, especially of the opportunistic infections, is gaining importance daily and pathologists now have the chance to make rapid diagnoses of these disorders by examining tissues and body fluids. Though parasitic infections and infestations occur mainly in subtropical and tropical areas, they are increasingly imported into other areas, where the pathologist must be able to recognize them. This new full-colour atlas, containing over 500 photographs, many diagrams and tables, with extensive references and index, concentrates on histology, differential diagnosis and on the structure of parasitic elements such as eggs, larvae and adult worms, in and outside tissues. The atlas will be invaluable as a bench manual for the practising pathologists to keep by the microscope, as well as for physicians, surgeons, dermatologists and pathologists in training, and all those who are concerned with parasitic infections. Table of ContentsConsultant Editor's Note. Preface. I: Parasitic Diseases. II: Protozoan Diseases. Haemoflagellate Infections. 1. American Trypanosomiasis. 2. African Trypanosomiasis. Leishmaniases. 3. Cutaneous Leishmaniasis. 4. Muto-Cutaneous Leishmaniasis. 5. Visceral Leishmaniasis. 6. Giardiasis. 7. Trichomoniasis. 8. Amoebiasis. 9. Acanthamoebiasis. 10. Blastocystis Infection. 11. Toxoplasmosis. 12. Babesiosis. 13. Sarcosporidiosis. 14. Isosporosis. 15. Cryptosporidiosis. 16. Malaria. 17. Pneumocystosis. 18. Balantidiasis. 19. Microsporidiosis. III: Helminthic Diseases. A. Nematodiasis. 20. Enterobiasis. 21. Ascariasis. 22. Trichuriasis. 23. Uncinariasis. 24. Strongyloidiasis. 25. Trichinosis. 26. Toxocariasis. 27. Anisakiasis. 28. Gnathostomiasis. 29. Angiostrongylosis. 30. Capillariasis. 31. Dracunculosis. Filaria Infections. 32. Filariasis. 33. Loiasis. 34. Onchocerciasis. 35. Dirofilariasis.36. Rare and Uncommon Nematodiases. 37. Larva migrans. B. Cestodiasis. 38. Taeniasis. 39. Diphyllobothriasis. 40. Dipylidiasis. 41. Hymenolepiasis. 42. Cysticercosis. 43. Echinococcosis. C. Trematodiasis. 44. Blood Flukes. 45. Lung Flukes. 46. Liver Flukes. 47. Intestinal Flukes. D. Worm Eggs. IV: Disorders by Arthropods. 48. Scabies. 49. Demodicidosis. 50. Tungiasis. 51. Myiasis. 52. Pentastomiasis.

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Book SynopsisThis atlas is the fruit of a many years' ex- eet atlas est Ie fruit d'une longue experience Dieser Atlas ist das Ergebnis langjlihriger Er- perience in the application of anatomico-clini- de la methode anatomo-clinique appliquee a fahrung mit der auf die ophthalmologische cal methods to ophthalmological oncology. I' oncologie ophtalmologique. Onkologie angewandten anatomisch-klini- schen Methode. In the field of ophthalmology, as in other En Ophtalmologie comme dans les autres dis- medical areas, oncology has progressively in- ciplines medicales, I' allongement progress if Wie auch in anderen Disziplinen gewinnt die creased in importance with the gradual de l'esperance de vie donne davantage Onkologie in der Ophthalmologie mit der lengthening of life expectation. Apart from d'importance a l'oncologie. En effet, mises a steigenden Lebenserwartung immer mehr an rare tumours and certain malformations in part les rares tumeurs de I' enfant et certaines Bedeutung. Von den wenigen Tumoren des children, neoformations in ophthalmology are malformations, les neoformations en Kindes und gewissen MiBbildungen largely confined to ageing patients. Any of the Ophtalmologie sont l'apanage preferentiel du abgesehen sind Neubildungen in der Ophthal- intraocular tissues may be affected: those of sujet age. Elles peuvent toucher tous les tis sus mologie in erster Linie dem lilteren Menschen the iris, the ciliary body, the choroid or the intra-oculaires: iris, corps ciliaire, choroYde, vorbehalten. Sie konnen an slimtlichen in- retina, as well as of the orbit and the eyelid.Trade Review' I recommend it as a useful addition to the library of an individual specializing in ophthalmic pathology and ocular oncology. ' Ophthalmic Practice: Asian Edition 1:1 1995 Table of ContentsDetailed table of contents.- Tumours of the Eyelids and the Conjunctiva.- I. Tumours of the epithelium and adnexa.- 1. Benign tumours.- 1.1 Benign tumours of the epithelium (without adnexa).- 1.1a Papillomas of the eyelid.- 1.1b Seborrheic keratosis.- 1.1c Conjunctival keratosis.- 1.1d Molluscum contagiosum.- 1.1e Kerato-acanthoma.- 1.2 Cysts.- 1.2a Epidermal and pilar cysts.- 1.2b Conjunctival cysts.- 1.3 Benign pilar tumours.- 1.3a Trichilemmoma.- 1.3b Tricho-epithelioma.- 1.3c Pilomatricoma.- 1.4 Benign sebaceous gland tumours.- 1.4a “Senile” sebaceous naevus of the eyelid.- 1.4b “Senile” sebaceous naevus of the caruncle.- 1.4c Meibomian adenoma.- 1.5 Sweat gland benign tumours.- 1.5a Hidrocystoma.- 1.5b Papillary syringadenoma.- 1.5c Syringomas.- 1.5d Eccrine acrospiroma.- 1.6 Oncocytoma of the caruncle.- 2. Precancerous epithelial tumours.- 2.1 Palpebral actinic keratosis.- 2.2 Conjunctival actinic keratosis.- 2.3 Conjunctival carcinoma in situ.- 2.4 Xeroderma pigmentosum.- 3. Malignant epithelial tumours.- 3.1 Basal cell carcinomas of the lids.- 3.2 Squamous cell (epidermoid) carcinoma of the lids.- 3.3 Squamous cell (epidermoid) carcinoma of the conjunctiva.- 3.4 Muco-epidermoid carcinoma of the conjunctiva.- 3.5 Sebaceous carcinomas.- 3.6 Sweat gland carcinomas.- II. Pigmented tumours of the lids and the conjunctiva.- 1. Benign pigmented tumours.- 1.1 Junctional naevus.- 1.2 Compound naevus.- 1.3 Intradermal naevus.- 1.4 Cystic benign naevus.- 1.5 Balloon cell naevus.- 1.6 Giant pigmented naevus.- 1.7 Juvenile melanoma of S. Spitz.- 1.8 Blue naevus of Tièche.- 2. Malignant melanomas of the eyelids and the conjunctiva.- 2.1 Precancerous Hutchinson-Dubreuilh melanosis.- 2.2 Superficial spreading melanoma.- 2.3 Nodular melanoma.- III. Xanthomatous tumours.- 1. Tuberous xanthoma of the lid.- 2. Xanthelasma.- 3. Juvenile xanthogranuloma of the eyelid and conjunctiva.- IV. Vascular benign tumours.- 1. Palpebro-conjunctival lymphangiomas.- V. Vascular malignant tumours.- 1. Kaposi’s sarcoma.- VI. Tumours of adipose tissue.- 1. Lipoma of the conjunctiva.- VII. Palpebro-conjunctival tumours of nerve tissue.- 1. Neurofibroma.- 2. Schwannoma.- 3. Merkel cell tumour.- VIII. Dysgenetic tumours of the conjunctiva, lids and orbit.- 1. Dermoid cyst.- 2. Dermoid of the limbus and dermis-like choristoma.- 3. Dermolipoma.- 4. Complex choristoma.- 5. Epibulbar osteoma.- IX. Inflammatory and degenerative pseudo-tumoral lesions.- 1. Chalazion.- 2. Pyogenic granuloma.- 3. Pinguecula.- 4. Pterygium.- 5. Palpebro-conjunctival amyloidosis.- Orbital and Orbito-Palpebral Tumours.- X. Fibrohistiocytic tumours.- 1. Benign fibrohistiocytoma.- 2. Malignant fibrohistiocytoma.- 3. Nodular fasciitis.- XI. Tumours of muscular tissue.- 1. Embryonal rhabdomyosarcoma.- XII. Benign palpebro-orbital vascular tumours.- 1. Cavernous haemangioma.- 2. Benign haemangio-endothelioma.- 3. Haemangio-pericytoma.- 4. Flat haemangioma.- 5. Intravascular vegetating haemangio-endothelioma.- XIII. Tumours of adipose orbital tissue.- 1. Lipoma.- 2. Liposarcoma.- XIV. Bone tumours.- 1. Osteoma.- 2. Bone haemangioma.- 3. Giant cell tumour.- 4. Osteosarcoma.- 5. Mesenchymatous chondrosarcoma.- XV. Pseudo-tumorous bone dysplasias.- 1. Fibrous dysplasia and ossifying fibroma.- 2. Bone cyst aneurysm.- XVI. Tumours of the neural tissue or neural-like tumours.- 1. Schwannoma.- 2. Orbital neurofibroma.- 3. Granular cell tumour.- 4. Alveolar soft part sarcoma.- 5. Sympathoblastoma.- XVII. Tumours of the infra-orbital optic nerve.- 1. Glioma.- 2. Meningiomas.- XVIII. Haemato-sarcomas.- 1. Lymphomas.- 2. Plasmacytomas.- 3. Granulocytic sarcoma.- XIX. Tumours of the lacrimal gland.- 1. Benign mixed tumour.- 2. Malignant tumours of the lacrimal gland.- 2.1 Adenoid cystic carcinoma.- 2.2 Carcinoma within a pleomorphic adenoma.- 2.3 Other carcinomas.- XX. Tumours of the lacrimal sac.- XXI. Pseudo-tumorous histiocytic lesions (X Histiocytoses).- 1. Eosinophilic granuloma of bone.- 2. Hand-Schuller-Christian disease.- 3. Sinus histiocytosis.- Tumours of the Uvea.- XXII. Iris tumours.- 1. Iris cysts.- 1.1 Primary cysts of the iris pigment epithelium.- 1.2 Secondary cystic proliferation.- 2. Iris pigmented tumours.- 2.1 Adenomas of the iris pigment epithelium.- 2.2 Melanocytic tumours of the iris stroma.- 3. Iris myogenic tumours.- 4. Juvenile xanthogranuloma.- 5. Metastases to the iris.- XXIII. Tumours of ciliary body.- 1. Epithelial tumours.- 1.1 Tumours of non-pigmented epithelium.- 1.1a Medullo-epitheliomas.- 1.1b Adult-type tumours.- 1.2 Tumours of the ciliary pigment epithelium.- 2. Melanocy tic tumours of the ciliary body stroma.- 2.1 Benign tumours.- 2.2 Ciliary body melanomas.- XXIV. Choroidal tumours.- 1. Melanocytic tumours and other neural crest-derived-tumours.- 1.1 Choroidal naevi.- 1.2 Choroidal tumours in neurofibromatosis.- 1.3 Melanosis oculi and naevus of Ota.- 1.4 Choroidal melanomas.- 2. Vascular tumours.- 2.1 Haemangiomas.- 3. Choroidal osteomas.- 4. Leukaemias and lymphomas.- 5. Metastatic carcinomas.- Tumours of the Retina and the Optic Disc.- XXV. Malignant tumour: Retinoblastoma.- XXVI. Glial tumours of the retina and the optic disc.- 1. Astrocytoma.- XXVII. Vascular tumours.- 1. Coats disease.- 2. Von Hippel’s disease.- XXVIII. Retina and disorders of the blood and blood forming organs.- XXIX. Tumours of the retinal pigment epithelium.- XXX. Melanocytoma of the optic disc.- XXXI. Drusen of the optic disc.- Technical appendix.- Literature.- Alphabetical index of subjects.

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Book SynopsisOur aim in producing a colour atlas of toxicological guidelines itemize the investigations to be carried out pathology was to present a catalogue of histopathologi­ during the course of the study and they normally include: cal lesions which we had encountered over the years in clinical observations and behaviour; food intake and body various laboratory animal species exposed to a vast weight measurements; serum biochemistry; haema­ range of pharmaceuticals, agrochemicals and industrial tology; ECG and ophthalmology. At the end of a study, chemicals. While we believe a colour atlas is the ideal full macroscopic and microscopic examinations of the way to share our experiences with others, it quickly organ weight analyses together with tissues are essen­ became clear to us that for the atlas to be meaningful tial. By far the greater part of the material used in this the associated text must be comprehensive and contain book is from toxicity studies conducted in recent years ample literature references. and performed in compliance with the Good Laboratory The atlas is intended for both the trainee and the Practice standards of governmental regulatory bodies in experienced toxicological pathologist working with lab­ Europe, Japan and North America. oratory animals in the pharmaceutical, agrochemical or Toxicity studies are commonly carried out in rats, chemical environment.Table of Contents1 The cardiovascular system.- 2 The respiratory system.- 3 The liver.- 4 The alimentary system and pancreas.- 5 The urinary system.- 6 The reproductive system.- 7 The endocrine glands.- 8 The lymphoid system.- 9 The nervous system.- 10 The eye and ear.- 11 The musculoskeletal system and skin.

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Book SynopsisDermatopathology is both exciting and exasperating. tum corneum cells. This occurs in disorders of keratiniza­ Skin has an elegant simplicity in its functions yet a tion because the process of desquamation is disturbed (Figure 1. 1). ferocious complexity in its structure. This is one of the paradoxes that underly the pathology of skin disease Parakeratosis. The presence of nucleated horn cells in and may go some way in explaining the multitudinous the stratum corneum. Normally the horn cells (corneocy­ disorders to which the skin is subject. The ready visibility tes) are thin lamellae of less than 1 f. lm thickness. They of the skin may also help explain why straightforward contain no detectable cytoplasmic contents as these are histological examination cannot always provide an lost in the granular cell layer. Parakeratosis occurs when answer to a clinicians's question. Quite dramatic appear­ the process of keratinization is disturbed such as when ances may be due to alterations of the relative rates of the rate of epidermal cell production is increased (as in blood flow, with or without oedema, in the different psoriasis) so that nuclei are not broken down before the vascular plexuses or around different structures in the stratum corneum is reached and when damage occurs horizontal dimension, neither of which may result in to the upper epidermis (Figure 1. 2). 'much to see' histologically. The inherent sampling error Porokeratosis.Table of ContentsI.- 1 Normal skin.- 2 Reactions to trauma and vascular injury.- II.- 3 Infections.- 4 Disorders of keratinization.- 5 Bullous and vesicular skin disorders.- 6 Eczema, psoriasis, lichen planus.- 7 Other inflammatory diseases.- 8 Connective tissue disease, vasculitis and erythemas.- 9 Acne, rosacea, perioral dermatitis and related disorders.- 10 Miscellaneous disorders of connective tissue.- 11 Scalp and hair disorders.- 12 Cutaneous deposits in metabolic disorders.- III.- 13 Melanocytic naevi and malignant melanoma.- 14 Benign epidermal tumours and cysts.- 15 Premalignant and malignant lesions of epidermis.- 16 Tumours of the dermis.- 17 Lymphocytic, mast-cell and atypical histiocytic skin tumours and dermal leukaemia.

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Book SynopsisThis book describes a standardized method for classifying and reporting invasive endometrial malignancies via direct endometrial sampling. Featuring a wealth of color illustrations, it provides specific diagnostic categories and cytomorphologic criteria to promote uniform and reliable diagnoses. It also describes the history of directly sampled endometrial cytology, reviews the sampling techniques and algorithmic approach, discusses specimen adequacy, and outlines challenges for the future. The Yokohama System for Reporting Endometrial Cytology – Definitions, Criteria and Explanatory Notes offers a valuable resource for researchers at clinical cytopathological laboratories around the world whose work involves gynecological cytology, oncology, pathology, and cytopathology. It will also appeal to researchers in the fields of cytotechnology, basic science, pathology and related industries, medical residents and clinicians.Table of Contents1. Endometrial Cytology in Historical Perspective 2. Overview of the Yokohama System for Reporting Endometrial Cytology 3. Pathogenetic Bases of the Yokohama System for Reporting Endometrial Cytology 4. Endometrial Cell Sampling Procedure to Obtain Cytologic Specimens 5. Algorithmic Interpretational and Diagnostic Approach to Endometrial Cytology for the Yokohama System 6. Evaluation of sample Adequacy: Cytologic criteria 7. Processing Methodology of Endometrial Cytology Samples 8. Negative for Malignant Tumors and Precursors: TYS1 9. Endometrial Hyperplasia without Atypia 10. Endometrial Atypical Hyperplasia / Endometrioid Intraepithelial Neoplasia 11. Malignant Neoplasms 12. Endometrial Glandular and Stromal Breakdown (EGBD) as Benign Mimics of Malignancy 13. Atypical Endometrial Cells (ATEC) 14. Cell Block Techniques for Endometrial Cytology Technical Procedures, Role of Immunocytochemistry, Advantages, Applications 15. Molecular Pathology of Endometrial Carcinoma: A general appraisal 16. Molecular Pathology of Endometrial Carcinoma on LBC Samples and Cell Blocks 17. Future Challenges and Perspectives of Endometrial Cytology 18. The Future Direction in Endometrial Oncology Through the Liquid Biopsy

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Book SynopsisThis textbook covers all aspects of rhinosporidiosis known till date and puts forward the various aspects of the disease on which further research can be carried out. Detailed descriptions of varied presentations of rhinosporidiosis managed at our institute is provided, accompanied by numerous clinical and intraoperative photographs. This book will serve as a comprehensive source of information related to all aspects of rhinoporidiosis. Experts from multiple specialties have contributed about aspects pertaining to their specialties.Table of Contents1. Introduction.- 2. Microbiological aspects.- 3. Epidemiology.- 4. Clinical presentation- ENT aspects- 5. Clinical presentation- ophthalmological aspects.- 6. Clinical presentation – cutaneous manifestations.- 7. Investigations.- 8. Surgical management.- 9. Pharmacological management.- 10. Pathological aspects.- 11. Immunological aspects.- 12. Our experience.- 13. Research topics.

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Book SynopsisThe second edition of this well-received book provides detailed information on the basic and advanced laboratory techniques in histopathology and cytology. It offers clear guidance on the principles and techniques of routine and special laboratory techniques. It also covers advanced laboratory techniques such as immunocytochemistry, flow cytometry, liquid-based cytology, polymerase chain reactions, tissue microarray, molecular technology, etc.The book's second edition covers several important recent topics with many new chapters, such as liquid biopsy, artificial neural network, digital pathology, and next-generation sequencing.Each chapter elucidates basic principle, practical methods, troubleshooting, and clinical applications of the technique. It includes multiple colored line drawings, microphotographs, and tables to illustrate each technique. The book is a helpful guide to the post-graduate students and fellows in pathology, practicing pathologists, as well as laboratory technicians, and research students.Table of ContentsPart I: Basic Laboratory Techniques in Histopathology LaboratoryChapter 1: Fixation of histology samples: Principles, methods and types of fixatives Chapter 2: Processing of tissue in histopathology laboratoryChapter 3: Embedding of tissue in histopathologyChapter 4: Decalcification of bony and hard tissue for histopathology processingChapter 5: Tissue Microtomy: principle and procedureChapter 6: Frozen section: Principle and procedureChapter 7: Staining principle and general procedure of staining of the tissueChapter 8: Haematoxylin and Eosin stain of the tissue sectionChapter 9: Special Stains for the carbohydrate, protein, lipid, nucleic acid and pigmentsChapter 10: Connective tissue stain: Principle and procedureChapter 11: Amyloid stainingChapter 12: Stains for the Microbial OrganismsPart II: Basic Laboratory Techniques in Cytology LaboratoryChapter 13: Cytology sample procurement, fixation and processingChapter 14: Routine staining in cytology laboratoryChapter 15: Basic technique of fine needle aspiration cytologyPart III: Advanced Techniques in Histology and Cytology LaboratoriesChapter 16: Immunocytochemistry in histology and cytologyChapter 17: Flow cytometry: Basic principles, procedure and applications in pathologyChapter 18: Digital pathology and whole slide imaging Chapter 19: Automation and liquid based cytology in cytology sampleChapter 20: Polymerase chain reaction: Principle, technique and applications in pathology Chapter 21: Fluorescent in situ hybridisation techniques in pathology: Principle, technique and applicationsChapter 22: Tissue microarray in pathology: Principal, technique and applications Chapter 23: Sanger sequencing and next generation gene sequencing: Basic principles and applications in pathologyChapter 24: Liquid biopsy: Basic principles, techniques and applications Chapter 25: Artificial neural network in Pathology: Basic principles and applicationsPart IV: Microscopy, quality control and laboratory organizationChapter 26: Light microscope and other different microscopesChapter 27: Fluorescence and confocal microscope: Basic principles and applications in pathologyChapter 28: Electron microscopy: Principle, components, optics and specimen processingChapter 29: Quality control and laboratory organization Chapter 30: Laboratory safety and laboratory waste disposalChapter 31: Multiple choice questions

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Book SynopsisSudden death is an uncommon condition. But when it occurs, especially in a young person, the acute loss can generate a substantial amount of grief with a great sense of disbelief. This mysterious and dreadful condition instils much fear and anxiety into the living, and more specifically for family members and friends. Understandably, the apprehension is brought about by the unexpectedness of the event and uncertainty of the consequences. The feeling of uneasiness is largely attributed to the lack of information regarding this condition. However in recent years, several causes of sudden death have been clarified. Treatment modalities have improved and reduced the occurrence of dying suddenly.This book is meant for anyone who wants to know more about sudden death. It aims to diminish its terror by explaining the various conditions that predispose individuals to sudden death and ways which may prevent it from occurring.

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Book SynopsisSection I: Bone sarcomas.- Ewing sarcoma/PNET.- Osteosarcoma.- Chondrosarcoma.- Section II: Soft tissue sarcomas.- Gastrointestinal stromal tumor (GIST).- Rhabdomyosarcoma.- Leiomyosarcoma- Uterine, to highlight the spectrum of endometrial sarcomas ranging from low grade ESS to high grade endometrial sarcomas to leiomyosarcoma.- Liposarcoma-retroperitoneal: well diff/dediff.- Undifferentiated pleomorphic sarcoma (UPS).- Angiosarcoma-to highlight the various vascular sarcomas, including kaposi.- Alveolar soft part sarcoma.- Synovial sarcoma.- Malignant peripheral nerve sheath tumor (MPNST).- Solitary fibrous tumor.- Dermatofibroma protuberans (DFSP).- Radiation induced sarcoma.- Section III: Soft tissue tumors with low malignant potential but aggressive local behavior.- Inflammatory myofibroblastic tumor.- Aggressive fibromatosis.- Giant cell tumor of the bone.- Chordoma.- Sarcoma survivorship/AYA.

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Book SynopsisChapter 1. Atherosclerosis is a Global No.1 Killer.- Chapter 2. Fatty Streaks: Initial (or Precursor) Lesions of Atherosclerosis.- Chapter 3. Atheroma and Its Complicated Lesions.- Chapter 4. Origin of the Foam Cell: The Leading Actor of Inflammation Hypothesis of Atherosclerosis.- Chapter 5. Origin of the Foam Cell: The Leading Actor of Inflammation Hypothesis of Atherosclerosis.- Chapter 6. Cholesterol and Its Carriers – Lipoproteins.- Chapter 7. Foam Cells: Mechanisms of Cholesterol Uptake, Storage, and Extracellular Release, and Their Pathophysiological Significance.- Chapter 8. Cell Death in Atherosclerosis: Apoptosis? or Necrosis? or more?.- Chapter 9. Macrophages as Phagocytes in Atherosclerosis: Heterophagy and Autophagy.- Chapter 10. Vascular Dendritic Cells: Their Roles in Atherosclerosis.- Chapter 11. Vascular Endothelial Cells and Atherosclerosis.- Chapter 12. Development of Initial Lesions and Their Progression to Atheroma.- Chapter 13. The Process of Atheroma Growth, Vulnerability, and Rupture.- Chapter 14. Familial Hypercholesterolemia.- Chapter 15. Cholesterol Embolism.- Chapter 16. Pathology of Acute Coronary Syndromes.- Chapter 17. Aortic Aneurysm and Acute Aortic Syndromes.- Chapter 18. Renovascular Hypertension and Related Conditions.- Chapter 19. Peripheral Arterial Disease of the Lower Extremities.- Chapter 20. Experimental Animal Models for the Study of Atherosclerosis.

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Book SynopsisChapter 1 Surgical Pathology of Tumors and Tumor-like Lesions in Gastrointestinal Tract.- Chapter 2 Surgical Pathology of Tumors and Tumor-like Lesions in Liver, Gallbladder and Pancreas.- Chapter 3 Surgical Pathology of Tumors and Tumor-like Lesions in Respiratory Tract and Mediastinum.- Chapter 4 Surgical Pathology of Tumors and Tumor-like Lesions in Head, Neck and Thyroid.- Chapter 5 Surgical Pathology of Tumors and Tumor-like Lesions in Urinary Tract and Male Reproductive System.- Chapter 6 Surgical Pathology of Tumors and Tumor-like Lesions in Female Reproductive System.- Chapter 7 Surgical Pathology of Tumors and Tumor-like Lesions in Lymph Node and Spleen.- Chapter 8 Surgical Pathology of Tumors and Tumor-like Lesions in Peritoneum and Retroperitoneum.- Chapter 9 Surgical Pathology of Tumors and Tumor-like Lesions in Bone and Soft Tissue.- Chapter 10 Surgical Pathology of Tumors and Tumor-like Lesions in Neuromuscular System.- Chapter 11 Surgical Pathology of Other Tumors and Tumor-like Lesions.

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