Neurosciences Books

Book SynopsisFrom the UK's foremost literary psychoanalyst, a dazzling new book on the universal urge to change our lives.We live in a world in which we are invited to changeto become our best selves through politics, or fitness, or diet, or therapy. We change all the timegrowing older and olderand how we think about change changes over time too.We want to think of our lives as progress mythsas narratives of positive personal growthat the same time as we inevitably age and suffer setbacks.Adam Phillips's sparkling book On Wanting to Change explores the stories we tell about change, and the changes we actually makeand the fact that they don't always go, or come, together.

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Book SynopsisTrade Review"For those who want to understand what’s happening to them and why grief is so confounding, this is a fascinating and comforting read.” — Oprah Daily “[A]n insightful book…fascinating look at what goes on inside our minds when we lose someone special.” — Wake-Up Call, Katie Couric Media “This book has helped so many who are grasping to make sense of loss, and I recommend it now, hoping that it will offer insights, solace, or even answers.” — Amanda Stern, How to Live (blog) “The Grieving Brain is a probing exploration into the science of grief and grieving. We are given an opportunity to view loss in a new way. If you have felt the pain of a loss and wondered if it will ever get better, O'Connor shows how the brain can help heal.” — Sharon Salzberg, author of Real Change “A pioneer of the neuroscience of grief, O'Connor lays out in simple prose how we try to make sense of the impossible conundrum of loss. Anyone who's been through a loss or just wants to know how bereavement works, this is the book for you.” — George Bonanno, author of The End of Trauma "We will all be touched by loss. To understand grief is to understand a fundamental human experience. This book is a powerful and comprehensive exploration of grief, the best I have read.” — Roshi Joan Halifax, PhD, pioneer in the end-of-life care field and author of Standing at the Edge and Being with Dying “Absorbing and wise, The Grieving Brain offers insights and coping mechanisms for those of us who have peered up from the depths of grief and wondered, why does this hurt so much? How can I make a meaningful life for myself now?” — Maryanne O’Hara, author of Little Matches "The Grieving Brain answered fascinating questions that I would not have thought to ask. State-of-science studies, fun facts and fascinating insights kept me turning pages and losing track of time." — Ira Byock, MD, active emeritus professor, Dartmouth Geisel School of Medicine, author of Dying Well and The Best Care Possible “[C]lear, confirming, compassionate, beautifully readable …” — Mad In America

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Book SynopsisA timely and important perspective on how people frame decisions and how relying on sacred values unwittingly leads to social polarization.When you are faced with a decision, do you consider the best outcome, or do you consider your deepest values about which actions are appropriate? The Cost of Conviction contrasts these two primary strategies for making decisions: consequentialism, the former, or prioritizing one?s sacred values, the latter. Steven Sloman argues that, while both modes of decision making are necessary tools for a good decision maker, people err by deploying sacred values more often than they should, especially when it comes to sociopolitical issues. As a result, we oversimplify, grow disgusted and angry, and act in ways that contribute to social polarization. In this book, Sloman provides a new understanding of today?s societal ills and grounds that understanding in science.The book begins by covering the philosophical and conceptual background of the two decision-making strategies, then takes a deep dive into the psychology of decision making. Drawing on historical and current examples of the use of the two strategies, the author provides a thorough overview of the psychology of decision making, including work on judgment, conscious and unconscious decision-making processes, the roles of emotion, and even an analysis of habit and addiction.With its unique emphasis on sacred values, The Cost of Conviction is an eye-opening must-read for all decision makers, especially those who wish to understand judgment, social decision making, and leadership.

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Book SynopsisThe Sunday Times top ten bestseller - neuroscientist Hannah Critchlow shows how our future is already largely hardwired into our brains. Like Sapiens and Thinking Fast and Slow, The Science of Fate revolutionises the way we understand our species and ourselves.

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Book SynopsisVestibular schwannoma is a rare benign tumor arising from VIII cranial nerve. Its localisation into internal auditory canal and cerebello-pontine angle is the main reason for the relevant clinical implication of such disease. This book develops all the features regarding the vestibular schwannoma, starting from the biology of the tumor, passing to the clinical presentation and instrumental diagnostic pathway to make diagnosis and concluding with therapeutic options linked to several factors regarding tumor size, localisation, symptoms, patient characteristics and outcome. The chapters are divided into 3 sections: pathophysiology, clinical features and treatment. Advancements in microsurgical technique and radiosurgery, coupled with an increased understanding of the natural history of the disease, have made modern management of this tumor considerably more complex and the opinions are still divided between conservatism and definitive cure. The last section includes the rehabilitation after treatment of patients affected by vestibular schwannoma. The contributions to this book were done by several eminent expert authors in their field, and all references are up to date. This is a robust resource for residents, fellows, and early attending physicians, as well as mid- to later-career physicians who care for patients with vestibular schwannoma.Table of ContentsPreface; Biology of Vestibular Schwannoma: The Role of PTEN and microRNA-21; Clinical Features, Instrumental and Imaging for Diagnosis of Vestibular Schwannoma; Neurofibromatosis Type 2; Imaging of Vestibular Schwannoma; Solitary Vestibular Schwannoma: Decision Making of Treatments; Conservative Management of Vestibular Schwannoma; The Enlarged Translabyrinthine Approach; The Retrosigmoid Approach: From the Microsurgical Anatomy to the Surgery; Middle Fossa Approach for Vestibular Shwannoma: An Overview; Endoscopic Approach to Vestibular Schwannoma; Radiotherapy for Vestibular Schwannoma; Facial Nerve Restoration after Vestibular Schwannoma Surgery; Vestibular and Proprioceptive Rehabilitation Strategy in Acoustic Neurinoma; Index.

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Book SynopsisTable of ContentsPreface to the second editionReproduction of altas figures in other publicationsAcknowledgementsIntroductionHistologyPreparation of photographs and drawingsThe construction of abbreviations in the Paxinos/Watson nomenclatureIdentification of structuresReferencesList of structuresIndex of abbreviationsFigures

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Book SynopsisPrinciples of Neurobiology, Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, figures in PowerPoint, and a Question Bank for adopting instructors.Trade ReviewProf Liqun Luo is the recipient of the 2020 Award for Education in Neuroscience granted by the Society for Neuroscience in recognition of his continuing commitment to both cutting-edge research and neuroscience education. The first edition of his textbook has been adopted by over 150 courses taught by major universities all of the world."This textbook from Dr. Liqun Luo is fantastic for advanced undergraduate courses on neurobiology. The emphasis on experiment-led explanations of neurobiology is critical for students transiting from textbook learning to thinking like modern scientist." - Marla B. Feller, Paul Licht Distinguished Professor in Biological Sciences, Division of Neurobiology, Department of Molecular and Cell Biology & Helen Wills Neuroscience Institute, University of California, Berkeley"Principles of Neurobiology is a stellar achievement of scholarship - a synthesis of the most interesting and important discoveries in neuroscience, written by a leader in our field who has based his text on a careful reading of thousands of primary research papers. Remarkably, this book does not just describe each 'discovery': it also describes the path to discovery, noting the specific technologies and experimental designs that enabled each key result." - Rachel Wilson, Martin Family Professor of Basic Research in the Field of Neurobiology, Harvard Medical School and Investigator, Howard Hughes Medical Institute"… what an extraordinary achievement this is – I don’t think there are many out there any longer who can cover the entire field of neuroscience in such a scholarly manner, singlehandedly! The integration that results from this is likely unique to this book." - Edvard Moser, Professor of Psychology and Neuroscience, Founding Director of the Kavli Institute for Systems Neuroscience, Norwegian University of Science and TechnologyProf Liqun Luo is the recipient of the 2020 Award for Education in Neuroscience granted by the Society for Neuroscience in recognition of his continuing commitment to both cutting-edge research and neuroscience education. The first edition of his textbook has been adopted by over 150 courses taught by major universities all of the world."This textbook from Dr. Liqun Luo is fantastic for advanced undergraduate courses on neurobiology. The emphasis on experiment-led explanations of neurobiology is critical for students transiting from textbook learning to thinking like modern scientist." - Marla B. Feller, Paul Licht Distinguished Professor in Biological Sciences, Division of Neurobiology, Department of Molecular and Cell Biology & Helen Wills Neuroscience Institute, University of California, Berkeley"Principles of Neurobiology is a stellar achievement of scholarship - a synthesis of the most interesting and important discoveries in neuroscience, written by a leader in our field who has based his text on a careful reading of thousands of primary research papers. Remarkably, this book does not just describe each 'discovery': it also describes the path to discovery, noting the specific technologies and experimental designs that enabled each key result." - Rachel Wilson, Martin Family Professor of Basic Research in the Field of Neurobiology, Harvard Medical School and Investigator, Howard Hughes Medical Institute"… what an extraordinary achievement this is – I don’t think there are many out there any longer who can cover the entire field of neuroscience in such a scholarly manner, singlehandedly! The integration that results from this is likely unique to this book." - Edvard Moser, Professor of Psychology and Neuroscience, Founding Director of the Kavli Institute for Systems Neuroscience, Norwegian University of Science and TechnologyTable of Contents1. An Invitation to Neurobiology. 2. Signaling within Neurons. 3. Signaling across Synapses. 4. Vision. 5. Wiring the Visual System. 6. Olfaction, Taste, Audition, and Somatosensation. 7. Constructing the Nervous System. 8. Motor Systems. 9. Regulatory Systems. 10. Sexual Behavior. 11. Memory, Learning, and Synaptic Plasticity. 12. Brain Disorders. 13. Evolution of the Nervous System. 14. Ways of Exploring.

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Book SynopsisIntroducing the Collins Modern Classics, a series featuring some of the most significant books of recent times, books that shed light on the human experience classics which will endure for generations to come.What if intelligent life on earth not only evolved on land, but also in the sea?Other Minds is a bold new story of how nature became aware of itself a story that largely occurs in the ocean, where animals first appeared. Tracking the mind's fitful development over millennia, Other Minds explores the incredible evolutionary journey of the cephalopods. What kind of intelligence do they possess? And how did the octopus, a solitary creature with little social life, become so smart?Heralded as the scuba-diving philosopher' when Other Minds first published, Peter Godfrey-Smith explores the underwater world and the concept of sentience to trace the question of inner life back to its roots. By comparing human beings with our most remarkable animal relatives, Other Minds casts crucial neTrade ReviewPraise for Other Minds: ‘Entrancing and profound’ Financial Times ‘A superb, coruscating book’ Literary Review ‘Startlingly incisive … refreshing guidance’ New York Times ‘Brilliant … The beauty of Godfrey-Smith’s book lies in the clarity of his writing; his empathy, if you will. He takes us through those early stirrings in the seas of deep time, from bacteria that sense light and can taste, to cnidarian jellyfish, the first organisms to exhibit nervous systems, which he describes wonderfully.’ Philip Hoare, Guardian ‘Fascinating and often delightful … This book ingeniously blends philosophy and science to trace the epic journey from single-celled organisms of 3.8 billion years ago to the awakening and development of cephalopod consciousness.’ The Times ‘As poignant as anything you will read this year’ Mail on Sunday ‘In Other Minds, Peter Godfrey-Smith, a philosopher, skilfully combines science, philosophy and his experiences of swimming among these tentacled beasts to illuminate the origin and nature of consciousness.’ The Economist ‘A delight on so many levels’ Dive magazine ‘To investigate these astonishing animals with such empathy and rigour is achievement enough. To do so while casting light on the birth and nature of consciousness, as Peter Godfrey-Smith does here, is captivating.’ China Miéville, author of Kraken ‘I love this book, its masterful blend of natural history, philosophy, and wonder … It’s a captivating story, and Peter Godfrey-Smith brings it alive in vivid, elegant prose … A must-read for anyone interested in the evolution of the mind – ours and the very other, but equally sentient, minds of the cephalopods.’ Jennifer Ackerman, author of The Genius of Birds

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Book SynopsisA leadership consultant and neuropsychologist identify the universal habits of the heart and mind—the keys to unlocking our true potential, creating our best selves and eliminating behavior patterns that hold us back.Trade Review"Heartstyles provided the 'aha' moment that made me reflect on my leadership approach and pivot. Often my team and I share stories of being 'below the line,' and have promised to suppose each other to lead with love and humility. We are on a journey to model these behaviors for the entire organization. Leading with heart is core to the transformation of our company culture and completely aligned with our purpose of helping people live better lives." — Milind Pant, CEO, Amway

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Book SynopsisA Next Big Idea Club Must-ReadA compelling and accessible new perspective on the modern science of psychology, based on one of Yale’s most popular courses of all timeHow does the brain—a three-pound wrinkly mass—give rise to intelligence and conscious experience? Was Freud right that we are all plagued by forbidden sexual desires? What is the function of emotions such as disgust, gratitude, and shame? Renowned psychologist Paul Bloom answers these questions and many more in Psych, his riveting new book about the science of the mind.Psych is an expert and passionate guide to the most intimate aspects of our nature, serving up the equivalent of a serious university course while being funny, engaging, and full of memorable anecdotes. But Psych is much more than a comprehensive overview of the field of psychology. Bloom reveals what psychology can tell us about the most pressing moral and political issues of our time—including belief in conspiracy theories, the role of genes in explaining human differences, and the nature of prejudice and hatred.Bloom also shows how psychology can give us practical insights into important issues—from the treatment of mental illnesses such as depression and anxiety to the best way to lead happy and fulfilling lives. Psych is an engrossing guide to the most important topic there is: it is the story of us.

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Book Synopsis?Nervous takes the focus from the abstract and does what doctors (and historians) failed to do: makes her story, her pain, and her life as real as any history that proceeded. Nervous gives face and weight to those forgotten women whose suffering has become little more than anecdotal collections of stories, not real people. It?s seamless and powerful. Nervous is a masterful personal narrative, beautifully written and captivating. It should? and will? be placed alongside some of the best well-crafted and compelling contemporary memoirs of this era.??Bassey Ikpi, New York Times bestselling author of I?m Telling the Truth but I?m LyingActivist Jen Soriano brings to light the lingering impacts of transgenerational trauma and uses science, history, and family stories to flow toward transformation in this powerful collection that brings together the lyric storytelling, cultural exploration, and thoughtful analysis of The Argonauts, The Woman Warrior, What My Bones Know, and Minor Feelings.The power of quiet can haunt us over generations, crystallizing in pain that Jen Soriano views as a form of embodied history. In this searing memoir in essays, Soriano, the daughter of a neurosurgeon, journeys to understand the origins of her chronic pain and mental health struggles. By the end, she finds both the source and the delta of what bodies impacted by trauma might need to thrive. In fourteen essays connected by theme and experience, Soriano traverses centuries and continents, weaving together memory and history, sociology and personal stories, neuroscience and public health, into a vivid tapestry of what it takes to transform trauma not just body by body, but through the body politic and ecosystems at large.Beginning with a shocking timeline juxtaposing Soriano?s medical history with the history of hysteria and witch hunts, Nervous navigates the human body?centering neurodiverse, disabled, and genderqueer bodies of color?within larger systems that have harmed and silenced Filipinos for generations. Soriano?s wide-ranging essays contemplate the Spanish-American War that ushered in United States colonization in the Philippines; the healing power of an inherited legacy of music; a chosen family of activists from the Bay Area to the Philippines; and how the fluidity of our nervous systems can teach us how to shape a trauma-wise future.With Nervous, Soriano boldly invites us along on a watershed journey toward healing, understanding, and communion.

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Book SynopsisJoy, sorrow, jealousy and awe - these and other feelings are the stuff of our daily lives. Presumed to be too private for science to explain and not to be essential for comprehending human rationality and understanding, they have largely been ignored. But not by the great seventeenth-century Dutch philosopher Spinoza. And not by Antonio Damasio. In this book Dr. Damasio draws on his innovative research and on his experience with neurological patients to examine how feelings and the emotions that underlie them support the governance of human affairs.Trade ReviewBig claims, well made: it is a rare pleasure to pick up such a rigorous and readable book about scientific advance that is so firmly anchored in philosophical history * Time Out *Virtually all the interesting philosophy today is done, not by professional philosophers, but by scientists like Damasio... The map may be incomplete, but thanks to Damasio we do at least know the principal landmarks * New Humanist *Damasio's book interweaves lucid and fascinating explanations of neurological findings with historical and philosophical ruminations on Spinoza... Rich and informative * New Scientist *There is much in this book to please Damasio's fans. He is a lively and humane writer, and ranges easily across a wide variety of topics * Independent *

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Book SynopsisWhy have all human cultures - today and throughout history - made music? Why does music excite such rich emotion? How do we make sense of musical sound? These are questions that have, until recently, remained mysterious. Now The Music Instinct explores how the latest research in music psychology and brain science is piecing together the puzzle of how our minds understand and respond to music. Ranging from Bach fugues to nursery rhymes to heavy rock, Philip Ball interweaves philosophy, mathematics, history and neurology to reveal why music moves us in so many ways. Without requiring any specialist knowledge, The Music Instinct will both deepen your appreciation of the music you love, and open doors to music that once seemed alien, dull or daunting, offering a passionate plea for the importance of music in education and in everyday life.''You''ll never listen to music the same way again'' - IndependentTrade ReviewWonderful account of why music matters... one of the finest and most versatile of current non-fiction writers * Sunday Times *Exemplary... In contemplating the mysteries of music we are also contemplating the mystery of ourselves... Ball, thankfully, doesn't try to provide any easy answers, but rather sends the reader back to the music a better listener * Observer *This is a truly fascinating and eye-opening account of a phenomenon so commonplace we barely think about it, yet one which is also mind-bogglingly complicated. Once you've read The Music Instinct, you'll never listed to music the same way again * Independent *A musical experience in itself...his love of the subject is abundantly evident.. His mastery of many scientific disciplines is a delight * Daily Telegraph *Impressively engaging...it will be the rare music lover that does not come away without having learned many interesting things * Guardian *

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Book SynopsisPaul Bloom is Professor of Psychology at University of Toronto and the Brooks and Suzanne Ragen Professor Emeritus of Psychology at Yale University. His research explores the psychology of morality, identity and pleasure. Bloom is the recipient of multiple awards and honours, including most recently the million-dollar Klaus J. Jacobs Research Prize. He has written for scientific journals such as Nature and Science, and for the New York Times, New Yorker, Atlantic and Guardian. He is the author or editor of eight books, including Just Babies, How Pleasure Works, Descartes' Baby and most recently Against Empathy.Trade ReviewWonderfully humane, lucid and entertaining ... a brave and necessary tract for the times * Telegraph *A great, provocative book ... that will legitimately change how you think about the world and your own sense of morality * The New York Times *Bloom dismantles the argument that empathy is the basis of all morality … Empathy, it turns out, is sentimental, superficial and racist * New Statesman *The title may shock, but this is a book of calm reason and expansive compassion. It’s also a pleasure to read: warm, lucid, and thought-provoking -- Steven Pinker, author of The Better Angels of Our NatureI couldn’t put this brilliantly argued book down. Engaging and witty, learned and stim­ulating, provocative and packed with cutting-edge findings, Against Empathy is sure to start many important debates * Amy Chua, author of Battle Hymn of the Tiger Mother *

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Book SynopsisProvides information for users in conjunction with brain atlases for the identification of brain structures, the connectivity between different areas, and to evaluate data collected in anatomical, physiological, pharmacological, behavioural, and imaging studies.Table of ContentsI: Evolution and Development Brain evolution, Nervous system, Fetal Development of the central nervous system, Development of the peripheral nervous system II: PERIPHERAL NERVOUS SYSTEM AND SPINAL CORD Peripheral motor system, Peripheral autonomic pathways, Spinal cord: cyto and chemo architecture, Spinal cord: connection III: BRAINSTEM AND CEREBELLUM Organization of human brain stem nuclei, Reticular formation: eye movements gaze and blinks, Periaqueductal gray, Raphe nuclei, Locus coeruleus, Substantia nigra, ventral tegmental area and retrobrul field, The brainstem cholinergic system, Cerebellum and precerebellar nuclei IV: DIENCEPHALON, BASAL GANGLIA, BASAL FOREBRAIN AND AMYGDALA Hypothalamus, Hypophysis, Circumventricular organs, Thalamus, The basal ganglia Basal forebrain, Amygdala V: CORTEX Architecture of the human cerebral cortex, Hippocampal formation, Cingulate gyrus, The frontal cortex/ lobes, Motor cortex, Posterior parietal cortex, Temporal cortex, Lower Brain Stem Regulation of Visceral, Cardiovascular and Respiratory Function VI: SYSTEMS Somatosensory system, Trigeminal sensory system, Pain system, Gustatory system, Olfaction, Vestibular system, Auditory system, Visual system, Emotional system, Cerebral vascular system

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Book SynopsisExamines whether there exists a unified conceptual framework for the field that is firmly based on scientific understanding regarding human development and functioning, that applies across all the clinical populations and practice areas within the field, and that would also help integrate professional psychology more fully into health care.Trade Review"Melchert's book is a valuable resource for graduate students and their faculty to understand how professional psychology is transforming into a health profession, while maintaining its unique psychological identity. I highly recommend it." --Dr. James Bray, Past President American Psychological Association, Editor, Primary Care Psychology and Handbook of Family PsychologyTable of Contents1. The Need for a Unified Conceptual Framework in Professional Psychology2. Professional Psychology as a Health Care Profession3. The Public We Serve: Their Mental Health Needs and Sociocultural and Medical Circumstances4. Resolving Conceptual and Theoretical Confusion in Professional Psychology5. The Biopsychosocial Approach: General Systems, Nonlinear Dynamical Systems, and Complexity Theory6. Ethical Foundations of Professional Practice7. A Unified Theoretical Framework8. Assessment9. Treatment Planning10. Treatment11. Outcomes Assessment12. Prevention and Public Health Perspective on Mental Health13. Implications for Professional Psychology Education and Practice

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Book SynopsisIncorporates findings on developmental gene expression and shows the boundaries of neuromeres in the diencephalon and brain stem. This book features: 161 thoroughly revised coronal diagrams and accompanying photographic plates spaced at 120 m intervals; and 19 thoroughly revised sagittal diagrams and accompanying photographic plates.Trade Review"…this version contains 161 revised coronal diagrams with accompanying photographic plates of microtome slides taken at 120 micrometer intervals through the brain from its anterior to posterior end…The book will be useful to students and teachers of neuroanatomy in medical schools, with additional uses in neurological research and specialist veterinary medicine." --ProtoView.com, March 2014Table of ContentsFeatures of the Edition Introduction Methods Stereotaxic reference system Nomenclature and the construction of abbreviations The basis of delineation of structures References Index of structures Index of abbreviations Parts of the rat brain Figures

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Table of ContentsPreface Part One: Biomechanical Concepts Chapter 1. Joint Torque Chapter 2. Stiffness and Stiffness-Like Measures Chapter 3. Velocity-Dependent Resistance Chapter 4. Mechanical Work and Energy Part Two: Neurophysiological Concepts Chapter 5. Muscle tone Chapter 6. Reflexes Chapter 7. Preprogrammed Reactions Chapter 8. Efferent Copy Chapter 9. Central Pattern Generator Part Three: Motor Control Concepts Chapter 10. Redundancy and Abundance Chapter 11. Motor Synergy Chapter 12. Equilibrium-Point Hypothesis Chapter 13. Motor Program Part Four: Examples of Motor Behaviors Chapter 14. Posture Chapter 15. Grasping Glossary

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Book SynopsisTable of ContentsNEURONS, SYNAPSES, AND CIRCUITS 1. Membrane Voltage 2. Dynamics of the Action Potential 3. Synaptic Transmission 4. Synaptic Plasticity 5. Neuromodulators 6. Neuronal Communication Beyond Synapses 7. Microcircuits of the Neocortex 8. Microcircuits of the Hippocampus MEASURING, PERTURBING, AND ANALYZING BRAIN NETWORKS 9. Unit Activity 10. LFP and EEG 11. Optical Measurements and Perturbations 12. Imaging Structural Networks With MRI 13. Imaging Functional Networks With MRI 14. Deep Brain Stimulation 15. Noninvasive Brain Stimulation 16. Network Interactions CORTICAL OSCILLATIONS 17. Low-Frequency Oscillations 18. Theta Oscillations 19. Alpha Oscillations 20. Beta Oscillations 21. Gamma Oscillations 22. High-Frequency Oscillations NETWORK DISORDERS 23. Parkinson’s Disease 24. Epilepsy 25. Schizophrenia 26. Autism Spectrum Disorders 27. Major Depressive Disorder TOOLBOXES Toolbox Neurons, Toolbox Animal Models, Toolbox Neurology, Toolbox Psychiatry, Toolbox Matlab, Toolbox Electrical Circuits, Toolbox Differential Equations, Toolbox Dynamical Systems, Toolbox Graph Theory, Toolbox Modeling Neurons, Toolbox Physics of Electric Fields, Toolbox Time and Frequency

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Book SynopsisTable of Contents1. Neural Induction 2. Polarity and Segmentation 3. Genesis and Migration 4. Generation of Neural Diversity 5. Wiring up the Brain: Axon Navigation 6. Differentiation 7. Naturally-Occurring Neuron Death 8. Synapse Formation 9. Refinement of Synaptic Connections 10. Behavioral Development

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Book SynopsisTable of ContentsSection I. Foundations and Principles of Geriatric Neurology 1. Geriatric pharmacotherapy: Appraising new drugs for neurological disorders in older patients 2. Animal models of cognitive aging and circuit-specific vulnerability 3. Psychopharmacology and pharmacokinetics 4. Models of care 5. Neurologic examination in the elderly 6. Cognitive and neuropsychological evaluation of the elderly 7. Chronic neurological disorders and related comorbidities: Role of age-associated physiological changes 8. Autonomic dysfunction: diagnosis and management 9. Epidemiology of aging and associated neurological disorders: Prevalence and incidence of Alzheimer disease and other dementias 10. Neuropsychology of aging 11. Cognitive reserve 12. Neuroimaging in aging and neurological diseases Section II. Neurological Disorders of Late-Life 13. Alzheimer disease 14. Parkinson disease – diagnosis and appreciation of comorbidities 15. Frontotemporal dementia 16. Recognizing and treating atypical Parkinson disorders 17. Down syndrome 18. The long-term consequences of repetitive head impacts: Chronic traumatic encephalopathy 19. Delirium in the critically ill patient 20. Vascular cognitive impairment: a preventable component of dementia 21. Stroke in the elderly 22. Gait and dementia 23. Assessment and treatment of major depression in older adults 24. Neuropsychiatric symptoms in dementia 25. Epilepsy and aging 26. Sleep physiology and disorders in aging and dementia Section III. General Topics in Geriatric Neurology 27. Urological function and dysfunction in aging: Diagnosis and treatment 28. Geriatric rehabilitation 29. Palliative medicine and end-of-life care 30. Headache in the elderly 31. Driving in the elderly in health and disease 32. The evolution of geriatric neurology

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Book SynopsisTable of Contents1. Introduction to Reasoning 2. Historical Perspectives on Reasoning 3. The Neuroscience of Reasoning 4. The Comparative Approach: Reasoning in Other Species Daniel Krawczyk and Aaron Blaisdell 5. Reasoning Origins: Human Development in Infancy and Childhood 6. Reasoning over the Lifespan 7. Disorders and their Effects on Reasoning 8. Causal Reasoning 9. Deduction and Induction 10. Analogical Reasoning 11. Decision Making and Abductive Reasoning 12. Social Reasoning 13. Future Directions: Emerging Technology and Cognitive Enhancement

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Book SynopsisTable of ContentsSECTION I. PHARMACOLOGICAL AND CLINICAL APPLICATIONS1. Overview of Brain Tumor Epidemiology and Histopathology2. Clinical Pharmacology of Brain Tumor Chemotherapy3. Antiepileptic drugs and chemotherapy: Potential interactions and impact on treatment of patients with cancer4. Brain Tumor Models for Cancer Therapy5. Genomics and proteomics in neuro-oncology6. Chemotherapy Resistance7. Clinical Trial Design and Implementation in Neuro-Oncology8. Biology of the Blood-Brain and Blood-Brain Tumor Barriers SECTION II. INNOVATIVE CHEMOTHERAPY DELIVERY9. Intra-arterial Chemotherapy10. Blood-Brain Barrier Disruption Chemotherapy11. Interstitial Chemotherapy and Polymer-Drug Delivery12. Intratumoral Chemotherapy and Convection-Enhanced Delivery13. Marrow-Ablative Chemotherapy with Autologous Hematopoietic Progenitor Cell Rescue in Brain Tumors14. CSF Dissemination of Primary Brain Tumors 15. Gene/Viral Treatment Approaches for Malignant Brain Cancer16. Nanoparticles as Therapeutic Agents for Brain Tumors SECTION III. MOLECULAR BIOLOGY AND MOLECULAR THERAPEUTICS17. Overview of Molecular Genetics of Brain Tumors18. Cell Cycle Regulation19. Targeting cell cycle proteins in brain cancer20. Apoptosis Pathways and Chemotherapy in Brain Tumors21. Growth Factor Signaling Pathways and Targeted Therapy22. Targeting the RAS-RAF-MEK-ERK Signaling Pathway in Gliomas23. PI3-kinase, Akt, mTOR and Treatment24. Scatter Factor/HGF and C-MET in Glioblastoma25. Targeting the sonic hedgehog pathway in brain cancers: Advances, limitations, and future directions26. Angiogenesis and angiogenesis inhibitors in brain tumors27. Bevacizumab and Brain Tumors28. Histone Deacetylase Inhibitors as Therapeutic Agents SECTION IV. CHEMOTHERAPY FOR SPECIFIC TUMORS – ADULTS 29. Historial and conventional chemotherapy approaches for high grade astrocytomas 30. The use of temozolomide for chemo-radiation and adjuvant therapy of high-grade gliomas31. Molecular Treatment of High-Grade Glioma32. Chemotherapy of Low-Grade Astrocytomas33. Chemotherapy of Oligodendrogliomas34. Chemotherapy of Primary Central Nervous System Lymphoma35. Chemotherapy for Medulloblastoma in Adults36. Chemotherapy of Adult Ependymoma 37. Chemotherapy for Glioneuronal Tumors38. Medical therapy of Schwannomas 39. Chemotherapy of Pineal Parenchymal Tumors40. Chemotherapy of Meningiomas41. Chemotherapy of Brain Metastases SECTION V. CHEMOTHERAPY FOR SPECIFIC TUMORS – PEDIATRICS42. Chemotherapy of Pediatric Low-Grade Gliomas43. Chemotherapy of Pediatric High-Grade Gliomas44. Chemotherapy for Medulloblastoma45. Chemotherapy of Brainstem Gliomas46. Germ Cell Tumors47. Chemotherapy of Ependymoma – Childhood48. Chemotherapy for CNS Atypical Teratoid/Rhabdoid Tumor49. Chemotherapy of Central Nervous System Primitive Neuro-Ectodermal Tumors50. Pediatric Choroid Plexus Carcinoma: Current Management and Future Directions SECTION VI. IMMUNOTHERAPY OF BRAIN TUMORS51. The Immune Response to Glioblastoma: Overview and Focus on Checkpoint Blockade52. Blockade of the Checkpoint Inhibitor Pathways and Activated T-cell Therapy in Brain Tumors53. Overview of Dendritic Cell Vaccines for Brain Tumors54. Overview of Vaccine Strategies against Epidermal Growth Factor Receptor in Brain Tumors55. Overview of CNS Vaccines – Pediatrics SECTION VII. RESPONSE ASSESSMENT, QUALITY OF LIFE, AND NEUROPSYCHOLOGY56. Issues in Response Assessment of Brain Tumor Chemotherapy57. Pseudoprogression in Neuro-Oncology: Overview, Pathophysiology, and Interpretation58. Response assessment in neuro-oncology (RANO): An update 59. Immunotherapy Response Assessment in Neuro-Oncology (iRANO)60. Quality of Life in Neuro-Oncology61. Neuropsychology of Chemotherapy in Brain Tumor Patients

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Book SynopsisTable of Contents1. Organization of the spinal cord 2. Development of the spinal cord 3. Vertebral column and spinal meninges 4. Spinal nerves 5. Primary afferent projections to the spinal cord 6. Cytoarchitecture of the spinal cord 7. Motor neurons of the spinal cord 8. The preganglionic motor column 9. Projections from the spinal cord to the brain 10. Projections from the brain to the spinal cord 11. Pattern generation in the spinal cord 12. Spinal cord transmitter substances 13. Gene expression in the neonate and adult mouse spinal cord 14. Spinal cord imaging 15. The lamprey spinal cord – Primordial vertebrate organization 16. Atlas of the rat spinal cord 17. Atlas of the mouse spinal cord 18. Atlas of the newborn mouse spinal cord 19. Atlas of the marmoset spinal cord 20. Atlas of the rhesus monkey spinal cord 21. Atlas of the human spinal cord

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Book SynopsisTable of ContentsSection 1 Dementia: Introductory Chapters 1. A review of the different types of dementia2. The classification of dementia: problems and challenges3. Alzheimer’s disease: an overview4. Dementia and competing hypothesis – the example of Alzheimer’s disease and its various hypotheses5. Lewy body dementia – an overview6. Mixed dementia – an overview7. Vascular dementia – an overview8. Linking in physical activity and dementia9. Risk factors in dementia10. Mortality in dementia – linking in delirium11. Rare forms of dementia12. Prion diseases and dementia13. Dementia in Parkinson disease14. Dementia in traumatic brain injury15. Risk factors in dementia – towards a coherent theory of dementia16. Genetics of dementia Section 2 Biomarkers, Psychometric Instruments, and Diagnosis 17. Circulating biomarkers in neurodegenerative dementias – YKL-40 and beyond18. Salivary biomarkers in Alzheimer’s disease19. Use of cerebrospinal fluid in diagnosis of dementias20. SPECT perfusion imaging in assessment of neurodegenerative dementias21. Computerised tomography (CT) in assessment of neurodegenerative dementias22. Magnetic resonance imaging (MRI) in assessment of neurodegenerative dementias23. Questionnaires: The mini-mental state examination (MMSE) and beyond24. The Cambridge Mental Disorders of the Elderly Examination (CAMDEX) and applications to dementia25. The Montreal Cognitive Assessment (MoCA) and applications to dementia26. The Hopkins Verbal Learning Test (HVLT) and applications to dementia27. The Addenbrooke’s Cognitive Examination (ACE) and applications to dementia28. ALBA Screening Instrument (ASI) and applications to dementia29. The prediction of Alzheimer’s disease Section 3 Pharmacological Treatments for Dementia30. Cholinesterase inhibitors in dementias – an overview31. NMDA receptor antagonists in dementia – an overview32. Donepezil usage – a focused review33. Rivastigmine usage – a focused review34. Galantamine usage – a focused review35. Memantine – a focused review36. Failures and successes of monoclonal antibodies – bapineuzumab and beyond37. Immunotherapies: an overview Section 4 Non-Pharmacological Treatments38. Internet counselling39. Counselling in dementia40. Cognitive rehabilitation in dementia41. Cognitive stimulation in dementia42. Anodal Transcranial Direct Current Stimulation43. Nanoparticles: nanodiamond treatment in Alzheimer’s disease44. Increasing intakes and improving nutritional status in dementia45. All-trans retinoic acid in Alzheimer’s disease46. Environmental enrichment in dementia47. Music therapy in dementia48. Aromatherapy in dementia49. Massage in dementia50. Dancing in dementia51. Multisensory Stimulation in Dementia52. Animal-assisted therapy in dementia53. Occupational therapy in dementia

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Book SynopsisTable of ContentsPart I: Genetics, molecular and cellular biology 1. The neuron navigator 2 gene and Alzheimer’s diseaseChun Xu, Brenda Bin Su, Stephanie Lozano and Kesheng Wang 2. Interlinking polymorphisms, estrogens, and Alzheimer diseaseLu Hua Chen, Leung Wing Chu and You-Qiang Song 3. Linking EEGs, Alzheimer disease, and the phosphatidylinositol-binding clathrin assembly protein (PICALM) geneNatalya Ponomareva, Tatiana Andreeva, Vitaly Fokin, Sergey Illarioshkin and Evgeny Rogaev 4. CD36 gene polymorphisms and Alzheimer’s diseaseOmar Šerý, Nandu Goswami and Vladimir J. Balcar 5. Genetic contributions to sporadic frontotemporal dementiaJessie S. Carr, Daniel W. Sirkis and Jennifer S. Yokoyama 6. Clinical response to cholinesterase inhibitors in dementia: the role of CYP2D6 and APOE genetic polymorphismsLuís Felipe José Ravic de Miranda, Karina Braga Gomes and Paulo Caramelli 7. A1 and A2 purinergic receptor expression in dementiaJ. Mendiola-Precoma, L.C. Berumen, A. Rodríguez-Cruz and G. García-Alcocer 8. Molecular aspects of metallothioneins in dementiasGemma Comes, Anna Escrig, Yasmina Manso, Olaya Fernández-Gayol, Paula Sanchis, Amalia Molinero, Mercedes Giralt, Javier Carrasco and Juan Hidalgo 9. Implication of microRNAs in Alzheimer’s disease pathogenesisKatarzyn Marta Zoltowska, Katarzyna Laskowska-Kaszub, Siranjeevi Nagaraj and Urszula Wojda 10. Role of cellular oxidative stress in dementiaGiovanna Galliciotti, Antonella De Jaco, Diego Sepulveda-Falla, Emanuela D’Acunto and Elena Miranda 11. Toward an integrative understanding of the neuroinflammatory molecular milieu in Alzheimer disease neurodegenerationJuan M. Zolezzi, Paulina Villaseca and Nibaldo C. Inestrosa 12. Wnt signaling and dementiaCarolina Alquezár and Ángeles Martín-Requero 13. Linkage of atypical protein kinase C to Alzheimer diseaseRobert V. Farese and Mini P. Sajan 14. Linking histone deacetylases and phosphodiesterase 5 in novel treatments for Alzheimer’s diseaseAna Garcia-Osta and Mar Cuadrado-Tejedor 15. Nuclear factor erythroid 2-related factor 2 in Alzheimer’s diseaseKelsey E. Murphy and Joshua J. Park 16. Implications of alpha- and beta-secretase expression and function in Alzheimer’s diseaseSven Reinhardt and Kristina Endres 17. Methylation analysis of DNA in Alzheimer’s diseaseFabio Coppedè 18. The signalosome malfunctions in age-associated neuropathologiesRicardo Puertas-Avendaño, David Quinto-Alemany, Miriam González-Gómez and Raquel Marin 19. FAM3C in Alzheimer’s disease: a risk-related molecule and potential therapeutic targetMasaki Nishimura, Naoki Watanabe, Emi Hibino, Masaki Nakano, Yachiyo Mitsuishi, Lei Liu and Takuma Sugi 20. Amylin and amylin receptors in Alzheimer’s diseaseWen Fu and Jack H. Jhamandas 21. Mammalian target of rapamycin complexes: regulation and Alzheimer’s diseaseHenry Querfurth and Han-Kyu Lee 22. Mammalian target of rapamycin complexes: protein synthesis and autophagy, Parkinson’s disease, amyotrophic lateral sclerosis, and frontotemporal dementiaHenry Querfurth and Han-Kyu Lee 23. Linking CD200 in brains and dementia: molecular aspects of neuroinflammationDouglas Gordon Walker Part II: Neurological, physiological and imaging 24. Hippocampal atrophy associated with dementia risk factors and dementiaHiroshi Yao, Yuko Araki, Fumio Yamashita, Makoto Sasaki and Manabu Hashimoto 25. Inflammation and insulin resistance in Alzheimer’s disease: partners in crimeYuval Nash and Dan Frenke 26. Brain susceptibility to hypoxia/hypoxemia and metabolic dysfunction in Alzheimer’s disease: insights from animal and in vitro modelsVito Antonio Baldassarro, Andrea Bighinati, Michele Sannia, Luciana Giardino and Laura Calzà 27. Neuropeptides and neurolipids: what they are and how they relate to Alzheimer’s diseaseIván Manuel, Laura Lombardero, Alberto Llorente-Ovejero and Rafael Rodríguez-Puertas 28. Neurotransmitter receptors in Alzheimer’s disease: from glutamatergic to cholinergic receptorsLaura Lombardero, Alberto Llorente-Ovejero, Iván Manuel and Rafael Rodríguez-Puertas 29. Aß42-a7-like nicotinic acetylcholine receptors and Alzheimer’s diseaseHoau-Yan Wang and Amber Khan 30. Synaptosomal bioenergetic defects in Alzheimer’s diseasePamela V. Martino Adami and Laura Morelli 31. Limitations of amyloid imaging in Alzheimer’s diseaseDavid Weidman 32. Linking gradient echo plural contrast imaging metrics of tissue microstructure with Alzheimer diseaseDmitriy A. Yablonskiy, Tammie L. Benzinger and John C. Morris 33. Hypertensive disorders during pregnancy and later dementia: is there a connection?Ellika Andolf 34. Unraveling the contributions of sleep dysfunction to Alzheimer’s diseaseElie Gottlieb, Natalie A. Grima, Mark Howard, Amy Brodtmann and Matthew P. Pase Part III: Behaviour and psychopathology 35. Overview of behaviors in dementiaDorothy M. Grillo and Rachel Anderson 36. Delirium superimposed on dementia: a clinical challenge from diagnosis to treatmentMorandi Alessandro, Pozzi Christian, Grossi Eleonora and Bellelli Giuseppe 37. Self-consciousness deficits in dementiaEva M. Arroyo-Anlló and Roger Gil 38. Attentional impairments to novel images in dementiaCelina S. Liu, Michael Rosen, Nathan Herrmann and Krista L. Lanctôt 39. Frontal lobe syndrome and dementiasPetronilla Battista, Chiara Griseta, Rosa Capozzo, Madia Lozupone, Rodolfo Sardone, Francesco Panza and Giancarlo Logroscino 40. The stigma of dementiaAlbert Aboseif and Benjamin K.P. Woo 41. Delusions in dementiasMadia Lozupone, Maddalena La Montagna, Antonello Bellomo, Petronilla Battista, Davide Seripa, Antonio Daniele, Antonio Greco, Onofrio Resta, Giancarlo Logroscino and Francesco Panza 42. Linking motor speech function and dementiaMatthew L. Poole and Adam P. Vogel 43. Spatial navigation and Alzheimer’s diseaseLaura E. Berkowitz, Ryan E. Harvey and Benjamin J. Clark 44. Violence and dementiaG. Cipriani, S. Danti, A. Nuti, L. Picchi and M. Di Fiorino 45. Factors contributing to protection and vulnerability in dementia caregiversFan Zhang, Sheung-Tak Cheng and Manuel Gonçalves-Pereira Part IV: Diet, nutrition and environment 46. Nutritional status of dementia and management using dietary taurine supplementationMi Ae Bae and Kyung Ja Chang 47. Selenium and Alzheimer’s diseaseAdriana Gisele Hertzog da Silva Leme and Barbara R. Cardoso 48. Linking adiponectin and obesity in dementiaMa1gorzata Bednarska-Makaruk 49. The impact of the gut microbiome in Alzheimer’s disease: cause or consequence?Malena dos Santos Guilherme and Kristina Endres 50. (-)-Epigallocatechin-3-gallate and Alzheimer’s diseaseLaura Xicota and Rafael de la Torre 51. Lead, cadmium and Alzheimer’s diseaseKelly M. Bakulski, Howard Hu and Sung Kyun Park Part V: Models and modelling in dementia 52. Alzheimer model 5xfad mice and applications to dementia: transgenic mouse models, a focus on neuroinflammation, microglia, and food-derived componentsTatsuhiro Ayabe and Yasuhisa Ano 53. Use of 192 IgG-saporin as a model of dementia and its applicationJ.W. Chang and Y.S. Park 54. Amyloid beta 1e42-induced animal model of dementia: a reviewJosiane Budni and Jade de Oliveira 55. Resources for the neuroscience of dementiaRajkumar Rajendram and Victor R. Preedy

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