Molecular biology Books
Sinauer Associates Is an Imprint of Oxford University Press Fundamentals of Molecular Evolution
Book SynopsisPublished by Sinauer Associates, an imprint of Oxford University Press. This book describes the dynamics of evolutionary change at the molecular level, the driving forces behind the evolutionary process, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology involved in dealing with molecular data from an evolutionary perspective, and the logic of molecular hypothesis testing. The second edition incorporates newly acquired evolutionary insight from genome projects involving bacteria, plants, and animals, as well as analytical tools that have been developed and perfected in the last decade, and has been brought up to date in line with the many advances in genomics, protein engineering, computational biology, and bioinformatics.The authors explain evolutionary phenomena at the molecular level in a way that can be understood without much prerequisite knowledge of molecular biology, evolution, or mathematics. Both mathematical and intuitive explanations are provided, and examples that support and clarify the many theoretical arguments and methodological discussions are included.Trade ReviewFundamentals Of Molecular Evolution can serve both as an excellent text book for students of different biological disciplines and as a very useful introduction into molecular evolution for professional readers. Undoubtedly, this book should be an essential purchase for all libraries in higher education institutions with biology departments. * V. N. Ksenzenko and Y. A. Trotsenko, Journal of Chemical Technology and Biotechnology *Table of ContentsIntroduction.- Genes, Genetic Codes, and Mutation.- Dynamics of Genes in Populations.- Evolutionary Change in Nucleotide Sequences.- Rates and Patterns of Nucleotide Substitution.- Molecular Phylogenetics.- Gene Duplication, Exon Shuffling, and Concerted Evolution.- Evolution by Transposition.- Genome Evolution.- Appendix I. Timetables of Evolution.- Appendix II. Basics of Probability.- Literature Cited.- Subject Index.- Appendix I: Spatial and Temporal Frameworks of the Evolutionary Process.- Appendix II: Basics of Probability.- Literature Cited.- Index.- Taxonomic Index.
£135.99
John Wiley and Sons Ltd Amino Acids and Proteins in Fossil Biominerals
Book SynopsisTable of ContentsPreface vii Acknowledgements ix 1 Biominerals and the Fossil Record 1 Why Study Old Biominerals? 1 What are Biominerals? 4 How and Why are Biominerals Formed? 5 ‘Biomineralization Toolkit’: From Proteins to Proteomes 8 Fossil Biominerals, Fossil Proteomes 12 References 16 2 Mechanisms of Degradation and Survival 23 Introduction 23 Hydrolysis 27 Racemization 31 Decomposition and Other Diagenesis-induced Modifications 35 References 38 3 Proteins in Fossil Biominerals 43 Bone and Other Collagen-based Hard Tissues 43 Tooth 45 Eggshell 47 Mollusc Shell 51 Other Substrates 57 References 63 4 Chiral Amino Acids: Geochronology and Other Applications 71 Dating the Quaternary (Pleistocene and Holocene) 71 Principles of AAR Dating 76 Measuring D/L Values 78 Factors Affecting D/L Values 82 Aminostratigraphy 87 Aminochronology 92 Palaeothermometry 97 Testing the Suitability of Biominerals for Geochemical Analyses 98 Taxonomic Identification 99 Appendix: Practical Tips on How to Plan and Conduct an AAR Study 100 References 104 5 Ancient Protein Sequences 113 Ancient Protein Analysis by Mass Spectrometry 113 Ancient Proteins: Past and Future 120 References 122 Index 127
£79.95
John Wiley and Sons Ltd Zika Virus and Diseases
Book SynopsisCompiles the most current information on the Zika virus and its associated diseases This comprehensive book provides the most up-to-date information for students, medical students, and scientists on Zika virus and its associated diseases. It includes all the information related to the Zika virus since its discovery in 1947; its epidemic outbreak in 2007-2014; how the epidemiology changed in America in 2015-2016; its mode of transmission; how to prevent and treat it; and associated diseases. Zika Virus and Diseases: From Molecular Biology to Epidemiology offers complete and up-to-date coverage in 10 chapters. It presents information from papers that attempted to associate the virus with diseases in Africa until the first animal experiment; discusses its association with Guillain-Barré syndrome and microcephaly; describes the basic mechanisms for Zika (ZIKV) replication, including important differences between Dengue (DENV), West-Nile virus (WNV), and ZIKV;Table of ContentsPreface ix List of Abbreviations xi 1 The History of ZIKV Discovery 1 1.1 ZIKV Isolation from Monkeys and Mosquitos 1 1.2 ZIKV Infection in Humans 6 1.3 ZIKV Infection Spread to Other Hosts and Regions 7 1.4 Cross‐Paths between ZIKV and Other Flaviviruses 9 References 10 2 ZIKV: From Silent to Epidemic 15 2.1 Outbreak in Yap Island (2007) 15 2.2 Outbreak in French Polynesia (2013) 16 2.3 How Did ZIKV Reach Brazil? 18 2.4 Outbreak in Brazil (2015) 18 2.5 ZIKV Spread through South, Central, and North Americas 20 References 22 3 ZIKV Transmission and Prevention 29 3.1 Modes of Transmission 29 3.2 Prevention 37 References 40 4 Association with Guillain‐Barre Syndrome and Microcephaly 49 4.1 Association with Neurological Disorders 49 References 58 5 ZIKV Animal Models 69 5.1 Animal Models: Embryonated Hen Eggs 69 5.2 Animal Models: Landrace Piglet 69 5.3 Animal Models: Mice 70 5.4 Animal Model: Nonhuman Primate 74 References 78 6 Biology of ZIKV 83 6.1 Structural and Physical Properties of ZIKV Virion 84 6.2 Binding and Entry 87 6.3 Genome Structure 89 6.4 Translation and Proteolytic Processing 91 6.5 Features of the Nonstructural Proteins 92 6.6 RNA Replication 100 6.7 Features of the Structural Proteins 104 6.8 Virus Assembly and Release from Virus‐Infected Cells 107 References 109 7 Zika Virus (ZIKV) Strains and Lineages 131 7.1 East and West African Lineage 131 7.2 Africa vs. Asian/American Lineage 132 References 140 8 ZIKV‐Host Interactions 147 8.1 Systematic Studies to Identify ZIKV Affected Functions and Pathways 147 8.2 Induction and Dysregulation of Innate Immune Responses during ZIKV Infection 150 8.3 Induction of Cell Death and Apoptosis by ZIKV 156 8.4 Induction of Autophagy by ZIKV 160 8.5 Dysregulation of Cell Cycle and Induction of Abnormal Mitosis by ZIKV 163 References 164 9 Inhibitors of ZIKV Replication and Infection 179 9.1 Drugs That Lead to the Destruction of ZIKV Virions 179 9.2 Drugs That Inhibit ZIKV Entry and Endocytosis 180 9.3 Drugs That Target ZIKV NS2B‐NS3 Protease Activity 186 9.4 Drugs That Target ZIKV NS5 RNA‐Dependent RNA Polymerase Activity 191 9.5 Neutralizing Antibodies That Target ZIKV Structural Protein 200 9.6 Drugs That Inhibit ZIKV Infection by Targeting Host Machinery 201 9.7 Drugs That Show Neuroprotective Activity but Do Not Suppress ZIKV Replication: Emricasan 205 9.8 Other Drugs That Inhibit ZIKV Infection Identified from a Screening of FDA‐Approved Drugs 206 References 210 10 Long‐Term Care and Perspectives 229 10.1 Prenatal Care and Diagnosis of Abnormal Fetus Development 229 10.2 Long‐Term Care for Patients Affected by ZIKV 230 10.3 Assistance to Families with Children Affected by ZIKV 230 10.4 Perspectives 231 References 232 Index 237
£103.50
OM Book Service Loose Leaf for Concepts of Genetics
Book Synopsis
£136.60
McGraw-Hill Companies Loose Leaf for Genetics Analysis and Principles
Book Synopsis
£140.40
Basic Books Life as We Made It: How 50,000 Years of Human
Book Synopsis
£22.50
American Society for Microbiology Principles of Microbial Diversity
Book Synopsis
£85.44
American Society for Microbiology Medical Biotechnology
Book Synopsis
£85.50
American Society for Microbiology Antibodies for Infectious Diseases
Book Synopsis
£102.60
American Society for Microbiology Molecular Microbiology: Diagnostic Principles and
Book Synopsis
£151.00
American Society for Microbiology Paleomicrobiology of Humans
Book Synopsis
£65.08
American Society for Microbiology Mobile DNA III
Book Synopsis
£121.00
American Society for Microbiology Virulence Mechanisms of Bacterial Pathogens
Book Synopsis
£108.90
Oxford University Press Inc The Cell: A Molecular Approach
Book SynopsisEven the most experienced instructor can find teaching cell biology daunting, and most cell biology texts are bogged down in detail or background information. Lost in all the details are the more fascinating material and contemporary advances that represent this rapidly moving field. With so much to cover, creating a classroom around active learning may be difficult or nearly impossible. The Cell: A Molecular Approach, Eighth Edition, endeavors to address those issues with succinct writing, incorporation of current research, a test bank that encourages critical thinking, and an active learning framework. With just enough detail for a one-semester, sophomore/junior level course, the text presents fundamental concepts and current research, including chapters on Genomics and Transcriptional Regulation and Epigenetics, and new in-text boxed features on Molecular Medicine and Key Experiments. Instructors will appreciate updates to the eighth edition test bank, such as raising the Bloom's level of questions overall, and giving instructors the ability to select questions based on level. Finally, for instructors who want to flip their classrooms or just get students more engaged, The Cell, Eighth Edition, is the only cell biology text that is accompanied by an Active Learning Guide. This chapter-by-chapter playbook shows instructors how to create a dynamic learning environment with in-class exercises, clicker questions, and links to relevant media, animations, testing, and self-quizzing, all aligned with the new in-text learning objectives, wherever appropriate. This text provides the right level of detail, student engagement, and instructor support for the modern cell biology classroom.Trade Review"I like the level of detail, modularity, resources and questions, and supplementary materials. I think the students like the clarity that the book provides. It is taught on a good level for undergraduates, especially those interested in medicine (teaching to the level of detail in the MCATs is always a good idea in my course)." -Nathan Jebbett, University of Vermont "I have not been able to find any other textbook that provides the key essential information related to this complex scientific area with the simplicity and depth provided in this textbook." -Germán Rosas-Acosta, The University of Texas at El Paso "This textbook is not too advanced for the medical students. Other textbooks (such as The Cell by Alberts) are more appropriate for PhD-level students with more details, but The Cell is a good, solid textbook for students in healthcare professions, with the 'right' amount of details." -Nancy Bae, Midwestern University "A formidable text on the molecular aspects of biology, biochemistry, cell function and regulation." -Floyd C. Knoop, Creighton UniversityTable of ContentsPart I: Fundamentals and FoundationsChapter 1. Introduction to Cells and Cell ResearchChapter 2. Molecules and MembranesChapter 3. Bioenergetics and MetabolismChapter 4. Fundamentals of Molecular BiologyChapter 5. Genomics, Proteomics, and Systems BiologyPart II: The Flow of Genetic InformationChapter 6. Genes and GenomesChapter 7. Replication, Maintenance, and Rearrangements of Genomic DNAChapter 8. RNA Synthesis and ProcessingChapter 9. Transcriptional Regulation and EpigeneticsChapter 10. Protein Synthesis, Processing, and RegulationPart III: Cell Structure and FunctionChapter 11. The NucleusChapter 12. Protein Sorting and TransportChapter 13. Mitochondria, Chloroplasts, and PeroxisomesChapter 14. The Cytoskeleton and Cell MovementChapter 15. The Plasma MembraneChapter 16. Cell Walls, the Extracellular Matrix, and Cell InteractionsPart IV: Cell RegulationChapter 17. Cell SignalingChapter 18. The Cell CycleChapter 19. Cell Renewal and Cell DeathChapter 20. Cancer
£181.58
American Society for Microbiology The Power of Plagues
Book Synopsis
£31.30
