Medicine and Nursing Books
McFarland and Company, Inc. Growing Up with a Schizophrenic Mother
Book Synopsis An estimated two to three million people in the United States today were raised by a schizophrenic parent. Brown and Roberts offer a unique book based on interviews with over forty adult children of mothers diagnosed as schizophrenic. Such topics as the isolation their family felt, their chaotic home environments, their present relationships with their mothers, and the lost potential of mother and child are covered. Their stories are fascinating and provide important information to both the mental health community and the lay public. The offspring have been described as having higher rates of increased aggressivity and sibling conflict, but often their circumstances strengthened these children and contributed to artistic and creative talents, resiliency, and high achievements. The authors provide an overview of schizophrenia, behaviors of the affected parent, and the marital relationship of the patient and her non-schizophrenic spouse. As adults, the respondents now shar
£999.99
SAC Publications,Switzerland Outdoor and Mountain Medicine: Mountaineering
Book SynopsisPublished by the Swiss Alpine Club, Outdoor and Mountain Medicine is a detailed reference work for everybody travelling in the mountains and keen to know more about medicine and health in the outdoors.In addition to first aid and makeshift rescue, topics like training and nutrition, women and children in high altitude, health problems on treks and expeditions, medical issues in rock climbing, canyoning, mountain biking and so on are explained by experienced mountain doctors. Countless practical tips are presented in an easy to understand format, supported with colour photos, illustrations and tables.
£37.95
Taylor & Francis Ltd Communications in the Building Industry
a huge range and FREE tracked UK delivery on ALL orders.
£42.99
Elsevier - Health Sciences Division Study Guide for Fundamentals of Nursing
Book Synopsis
£35.14
Deep & Deep Publications Health and Human Development
Book Synopsis
£46.49
Obelisco Salud Ayurveda
Book Synopsis
£23.71
Elsevier - Health Sciences Division Clinical Companion for Fundamentals of Nursing
Book SynopsisTable of ContentsCHAPTER 1 Medical, Nursing, and Health Professions Terminology CHAPTER 2 Communication CHAPTER 3 Interprofessional Collaboration and Delegation CHAPTER 4 Clinical Judgment and the Nursing Process CHAPTER 5 Documentation CHAPTER 6 Patient Interview CHAPTER 7 Vital Signs CHAPTER 8 Physical Assessmen CHAPTER 9 Pain Assessment CHAPTER 10 Skin, Hair, and Nail Assessment CHAPTER 11 Head, Eyes, Ears, Nose, and Throat Assessment (HEENT) CHAPTER 12 Respiratory Assessment CHAPTER 13 Cardiac and Peripheral Vascular Assessment CHAPTER 14 Musculoskeletal Assessment CHAPTER 15 Neurological Assessment CHAPTER 16 Abdominal Assessment CHAPTER 17 Breast and Genital Assessment CHAPTER 18 Safety CHAPTER 19 Equivalents and Dosage Calculation CHAPTER 20 Medication Administration CHAPTER 21 Infection Control CHAPTER 22 Mobility and Positioning CHAPTER 23 Personal Care CHAPTER 24 Wound Care CHAPTER 25 Oxygen Administration CHAPTER 26 Nutrition and Diets CHAPTER 27 Diagnostic Testing and Procedures CHAPTER 28 Preoperative and Postoperative Care CHAPTER 29 Emergent Clinical Situations CHAPTER 30 Death and Dying Index
£31.34
Taylor & Francis Everyday Community Practice
Book SynopsisThis book provides a practical but sophisticated exploration of community development practice and is an accessible, relevant, and contextualised guide for those studying social work and human services in Australia. This fully revised and expanded second edition (including new insights from communities preparing for, responding to, and recovering from disasters) draws on the experiences of not only the authors but many current practitioners from diverse backgrounds working alongside communities to support socially just change. The perspectives of these practitioners are drawn on throughout the book as well as in the exemplary projects case studies at the end of the book. Blending practical skills and ideas with a solid theoretical foundation, each chapter includes reflective questions and examples which can be used both on the classroom and in the field.Enabling students to feel better supported in challenging dominant individualised practice frameworks, it argues strongly that only collective action (supported by community development practice) can address significant social challenges such as those created by climate change, poverty, and social exclusion.
£37.99
Konark Publishers Pvt.Ltd Survive Covid: by Staying Alkaline
Book Synopsis
£6.64
Elsevier - Health Sciences Division Fundamentals of Nursing
Book Synopsis
£114.94
Cambridge University Press Cytohistology of Focal Liver Lesions
£107.73
Cambridge University Press Magnetic Resonance Imaging in Movement Disorders
Book SynopsisMagnetic Resonance Imaging in Movement Disorders is the first book to focus in detail on MRI in a range of movement disorders. Since MRI was first employed in imaging Parkinson''s disease, the number of imaging techniques and their application in diagnosis and management has extended widely. The book shows various imaging strategies ranging from functional, structural and chemical methods as they relate to both motor and non-motor aspects of Parkinson''s disease and other conditions such as Huntington''s disease and dystonia. Chapters on MRI in surgery and using MRI as a potential outcome measure in clinical trials show the clinical relevance of methods. Novel methods including DTI, tractography and resting case studies are described in detail. The book also summarises the relevance of fMRI to various aspects of movement disorders. Magnetic Resonance Imaging in Movement Disorders is essential reading for neurologists, radiologists and movement disorder specialists.Table of Contents1. Magnetic resonance imaging (MRI) methods in Parkinson's disease Silvia Mangia, Shalom Michaeli and Paul J. Tuite; 2. Imaging iron in Parkinson's disease W. R. Wayne Martin; 3. Motor Parkinson's disease and structure Stephane Lehericy, Cyril Poupon and Cecile Gallea; 4. MR imaging of Parkinson's disease with cognitive impairment and dementia Richard Camicioli; 5. fMRI of motor signs in Parkinson's disease Tobias Wächter; 6. Functional MRI of cognition and mood in Parkinson's disease Alison Simioni and Alain Dagher; 7. Networks and resting-state in Parkinson's disease Nazanin Baradaran and Martin J. McKeown; 8. MRI for targeting in surgical treatment of movement disorders Aviva Abosch and Noam Harel; 9. MR imaging and spectroscopy in Huntington's disease Isabelle Iltis and Janet Dubinsky; 10. Neuroimaging of Tourette's syndrome Yulia Worbe and Andreas Hartmann; 11. Dystonia Bernhard Haslinger; 12. Tauopathies Jennifer L. Whitwell and Keith A. Josephs; 13. Magnetic resonance imaging of multiple system atrophy Klaus Seppi, Christoph Mueller, Gregor K. Wenning and Michael Schocke; 14. Ataxia Kathrin Reetz and Ferdinand Binkofski; 15. Magnetic resonance spectroscopy in Parkinson's disease Uzay E. Emir and Gülin Öz; 16. The image of essential tremor: current neuroimaging and clues to disease localization, pathogenesis and diagnosis Hiral Shah and Elan D. Louis; 17. Adult clinical applications Michael Samuel and Jozef Jarosz; 18. MRI in clinical trials Norbert Schuff; Index.
£129.60
Cambridge University Press Adult Hydrocephalus
Book SynopsisAdult hydrocephalus is an insidious yet treatable condition that develops slowly, with usual onset around 60 years of age. It is poorly recognized and many cases are not diagnosed until late in the course of disease, leading to poorer patient outcomes and a high financial cost to healthcare providers. The resulting neurological symptoms include gait/balance problems, loss of bladder control, and a cognitive decline leading to dementia, which is often mistaken for Alzheimer''s disease. This book - the first published on this topic since 1993 - provides comprehensive guidelines to improve the speed and accuracy of diagnosis, and covers various neurosurgical techniques used to treat the disease, including the insertion of different types of shunts and endoscopic third ventriculostomy. This is essential reading for neurologists, neurosurgeons, family physicians, and radiologists who may well encounter adult patients with hydrocephalus more often than they realize.Table of ContentsPrologue; Part I. Basic Sciences: 1. Anatomy and physiology of the cerebrospinal fluid system Thomas A. Kosztowski, Aristotelis Filippidis, Rory Goodwin, Benjamin Elder and Daniele Rigamonti; 2. Neuropathology of human hydrocephalus Marc R. Del Bigio; 3. Animal models of hydrocephalus Marianne Juhler; 4. Genetics of hydrocephalus Jun Zhang; 5. The epidemiology of hydrocephalus Are Brean and Per Kristian Eide; Part II. Pathophysiology: 6. Pathophysiology of gait dysfunction in normal pressure hydrocephalus Jonathan Pindrik, Amy Bastian and Daniele Rigamonti; 7. The pathophysiologic basis of cognitive dysfunction in idiopathic normal pressure hydrocephalus Norman Relkin and Heather Katzen; 8. Incontinence and lower urinary tract symptoms in normal pressure hydrocephalus Adam P. Klausner and Samuel P. Robinson; 9. Normal pressure hydrocephalus grading scales Masatsune Ishikawa; Part III. Diagnosis: 10. The differential diagnosis of normal pressure hydrocephalus Marianne Juhler, Daniele Rigamonti and Carsten Wikkelso; 11. Core imaging in adult hydrocephalus Benjamin D. Elder, Patrick Bankah, Ari M. Blitz, Rory C. Goodwin, Thomas A. Kosztowski, Ignacio Jusué-Torres and Daniele Rigamonti; 12. Imaging of the cerebrospinal fluid circulation Olivier Balédent; 13. Cerebrospinal fluid dynamics and infusion techniques Cemil Kayis and Gunes A. Aygok; 14. Monitoring of intracranial pressure and assessment of cerebrospinal fluid dynamics Marek Czosnyka, Martin U. Schuhmann, Stefano Signoretti, Zofia Czosnyka and John D. Pickard; 15. Cerebrospinal fluid biomarkers in idiopathic normal pressure hydrocephalus Andrew A. Tarnaris; Part IV. Treatment and Outcomes: 16. Hydrocephalus shunt procedures Benjamin D. Elder and Daniele Rigamonti; 17. Hydrocephalus shunts: principles, hardware, shunt testing Zofia Czosnyka, Krzysztof Cieslicki, John D. Pickard and Marek Czosnyka; 18. Management of shunts in normal pressure hydrocephalus: follow-up and late complications Ahmed Mohyeldin, Ammar Shaikhouni and John McGregor; 19. Endoscopic third ventriculostomy: indications, technique, outcome, and complications Steffen Fleck, Jörg Baldauf and Henry W. S. Schroeder; 20. Outcome of idiopathic normal pressure hydrocephalus Gunes A. Aygok; Part V. Associated Conditions: 21. Normal pressure hydrocephalus syndrome secondary to hemorrhage, infection and malignancy Rory C. Goodwin and Daniele Rigamonti; 22. Low-pressure syndromes and cerebrospinal fluid leaks: diagnosis and management Debraj Mukherjee and Wouter I. Schievink; 23. Management of the adult with congenital hydrocephalus Jonathan Pindrik and Edward S. Ahn; 24. Management of hydrocephalus with associated cerebrospinal fluid pathologies Petra Margarete Klinge; 25. Chiari malformation and hydrocephalus in adults Aristotelis S. Filippidis and Harold L. Rekate; 26. Pseudotumor cerebri syndrome John D. Pickard and Nicholas Higgins; Epilogue; Index.
£118.75
Cambridge University Press The Genetic Basis of Sleep and Sleep Disorders
Book SynopsisThe first comprehensive book on the subject, The Genetic Basis of Sleep and Sleep Disorders covers detailed reviews of the general principles of genetics and genetic techniques in the study of sleep and sleep disorders. The book contains sections on the genetics of circadian rhythms, of normal sleep and wake states and of sleep homeostasis. There are also sections discussing the role of genetics in the understanding of insomnias, hypersomnias including narcolepsy, parasomnias and sleep-related movement disorders. The final chapter highlights the use of gene therapy in sleep disorders. Written by genetic experts and sleep specialists from around the world, the book is up to date and geared specifically to the needs of both researchers and clinicians with an interest in sleep medicine. This book will be an invaluable resource for sleep specialists, neurologists, geneticists, psychiatrists and psychologists.Table of ContentsPreface; Part I. General Principles of Genetics and Genomics: 1. Methods in complex trait analysis: mapping the genetic basis of sleep using model organisms Amelie Baud and Jonathan Flint; 2. Linkage and associations Elizabeth J. Rossin and Benjamin M. Neale; 3. Genome-wide association study approaches to sleep phenotypes Patrick Sleiman, Michael March and Hakon Hakonanson; Part II. Genetics of Sleep and Circadian Rhythms: 4. Genetic epidemiology of sleep and sleep disorders Christer Hublin and Jaakko Kaprio; 5. Drosophlia model systems for genetic sleep research Stephane Dissel and Paul J. Shaw; 6. Caenorhabditis elegans and zebrafish in sleep research David A. Prober and David M. Raizen; 7. Optogenetic control of arousal neurons Antoine Adamantidis, Matthew E. Carter and Luis De Lecea; 8. Prostaglandin D2 in the regulation of sleep Yoshihiro Urade and Michael Lazarus; 9. Astroglial regulation of sleep Marcos G. Frank; 10. The role of metabolic genes in sleep regulation Matthew S. Thimgan and Karen D. Schilli; 11. A systems biology approach for uncovering the genetic landscape for multiple sleep-wake traits Peng Jiang, Andrew Kasarskis, Christopher J. Winrow, John J. Renger and Fred W. Turek; 12. Genetic control of the circadian pacemaker Ethan Buhr and Joseph S. Takahashi; 13. Epigenetic basis of circadian rhythms and sleep disorders Irfan A. Qureshi and Mark F. Mehler; Part III. Sleep Physiology and Homeostasis: 14. Genetics of sleep and EEG Thomas Curie and Mehdi Tafti; 15. Genetic interaction between circadian and homeostatic regulation of sleep Valérie Mongrain and Paul Franken; 16. Genetic approaches to understanding circadian entrainment Till Roenneberg and Karla V. Allebrandt; 17. Animal models for cognitive deficits induced by sleep deprivation Laurent Seugnet and Paul Salin; 18. Individual differences in sleep duration and responses to sleep loss Devon A. Grant and Hans P. A. Van Dongen; 19. Clock polymorphisms associated with human diurnal preference Simon N. Archer and Derk-Jan Dijk; 20. Sleep and long-term memory storage Jennifer H. K. Choi and Ted Abel; 21. Sleep and synaptic homeostasis Chiara Cirelli and Giulio Tononi; Part IV. Insomnias: 22. Heritability and genetic factors in chronic insomnia Yves Dauvilliers and Charles M. Morin; Part V. Narcolepsy and Hypersomnias: 23. HLA and narcolepsy Katsushi Tokunaga and Makoto Honda; 24. Orexin (hypocretin) and narcolepsy Takeshi Sakurai and Seiji Nishino; 25. Gene-wide association studies in narcolepsy Hyun Hor; 26. Genetic disorders producing symptomaric narcolepsy Seiji Nishino and Takashi Kanbayashi; 27. Genetics of recurrent hypersomnia Michael Billiard, Rosa Periata-Adrados and Mehdi Tafti; Part VI. Sleep-related Breathing Disorders: 28. Linkage and candidate gene studies of obstructive sleep apnea Annette C. Fedson, Thorarinn Gislason and Allan I. Pack; 29. Genomic mutations and genotype-phenotype in pediatric sleep-related breathing disorders Leila Kheirandish-Gozal and David Gozal; Part VII. Circadian Rhythm Sleep Disorders: 30. Genetic of familial advanced sleep phase Suet Ying Chong, Louis J. Ptacek and Ying-Hui Fu; 31. Delayed sleep phase disorder, circadian genes, sleep homeostasis and light sensitivity Simon N. Archer and Derk-Jan Dijk; Part VIII. Parasomnias and Sleep-related Movement Disorders: 32. Family and genome-wide association studies of restless legs syndrome Eva C. Schulte and Juliane Winkelmann; Part IX. Psychiatric and Medical Disorders: 33. Circadian clock genes and psychiatric disorders Marc Cuesta, Nicholas Cermakian and Diane B. Boivin; 34. Genetics of autosomnal dominant nocturnal frontal lobe epilepsy Keivan Kaveh Moghadam and Giuseppe Plazzi; Part X. Medication Effects: 35. Gene therapy for sleep disorders Dheeraj Pelluru, RodaRani Konadhode, Carlos Blanco-Centurion, Meng Liu and Priyattam J. Shiromani; Index.
£82.64
Cambridge University Press Experimental Design for Laboratory Biologists
Book SynopsisSpecifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.Trade Review'This is a wonderfully lucid introduction to experimental design, written by an author who is clearly aware of the pitfalls that exist for the unwary experimenter. The focus is on how to design experiments to ensure reproducible research, with many examples illustrating general principles that need to be understood to avoid error and bias. The coverage of statistical analysis follows on naturally from the design issues, and is amply illustrated with exercises in R. Highly recommended.' Dorothy Bishop, University of Oxford'Worldwide there is a salient discussion about deficiencies in the validity and predictiveness of research in the life sciences. Indeed, a fullblown 'reproducibility crisis' has been proclaimed. Against this backdrop this important textbook is a timely and highly useful contribution in the pressing quest to improve the robustness, rigor, and reproducibility of current biological and preclinical research. Proper experimental design is the bedrock for obtaining reliable evidence. By providing the necessary conceptual know-how and practical knowledge, [this book] enables investigators in all stages of their careers to minimize bias and improve statistical power through proper design and analysis of their experiments. This volume is unique … [as] it is immensely readable and accessible even for those with little previous knowledge, in combining all relevant aspects in a practical, concise and comprehensive manner, and in its clear focus on factors that help to improve the quality of research.' Ulrich Dirnagl, Charité University Hospital, Germany'There is an increasing need to better design experiments not only to reduce the number of any animals being used in any such work, but also to ensure that the data so produced is meaningful. As part of that process knowing how to power studies and then properly analyse the data so generated is vital, and of late there have been concerns that this is not been done to same vigour as that seen in the clinical arena. However, most scientists struggle with this aspect of their work, and thus it is really refreshing to come across a book that explicitly deals with experimental design and analysis. This new book clearly lays out what can and should be done and is written by an acknowledged expert and I have no doubt that this book will become a recommended read for all those contemplating undertaking work of this type.' Roger Barker, University of CambridgeTable of Contents1. Introduction: 1.1 What is reproducibility?; 1.2 The psychology of scientific discovery; 1.3 Are most published results wrong?; 1.4 Frequentist statistical interference; 1.5 Which statistics software to use?; 2. Key ideas in experimental design: 2.1 Learning versus confirming experiments; 2.2 The fundamental experimental design equation; 2.3 Randomisation; 2.4 Blocking; 2.5 Blinding; 2.6 Effect type: fixed versus random; 2.7 Factor arrangement: crossed versus nested; 2.8 Interactions between variables; 2.9 Sampling; 2.10 Use of controls; 2.11 Front-aligned versus end-aligned designs; 2.12 Heterogeneity and confounding; 3. Replication (what is 'N'?): 3.1 Biological units; 3.2 Experimental units; 3.3 Observational units; 3.4 Relationship between units; 3.5 How is the experimental unit defined in other disciplines?; 4. Analysis of common designs: 4.1 Preliminary concepts; 4.2 Background to the designs; 4.3 Completely randomised designs; 4.4 Randomised block designs; 4.5 Split-unit designs; 4.6 Repeated measures designs; 5. Planning for success: 5.1 Choosing a good outcome variable; 5.2 Power analysis and sample size calculations; 5.3 Optimal experimental designs (rules of thumb); 5.4 When to stop collecting data?; 5.5 Putting it all together; 5.6 How to get lucky; 5.7 The statistical analysis plan; 6. Exploratory data analysis: 6.1 Quality control checks; 6.2 Preprocessing; 6.3 Understanding the structure of the data; Appendix A. Introduction to R; Appendix B. Glossary.
£104.50
Cambridge University Press Manual of Stem Cell and Bone Marrow Transplantation
Book SynopsisFully revised throughout, the second edition of Manual of Stem Cell and Bone Marrow Transplantation is based on the in-house handbook used at the world-renowned Dana-Farber Cancer Institute. It is a practical pocket manual for all members of the stem cell and bone marrow transplant team. Written by experts at Dana-Farber, the contents are handily arranged in outline format for maximum usefulness and convenience. This essential and user-friendly manual covers all aspects of the transplantation process, from stem cell processing through management of transplant-related complications. Topics discussed thoroughly include evaluation and counselling of patients and donors, preventative care, graft-versus-host disease and conditioning regimens. A new extensive chapter on oral health in stem cell transplantation has been added. These features make the Manual of Stem Cell and Bone Marrow Transplantation an ideal resource for the entire transplant team.Table of ContentsAcknowledgements; 1. Rationale for transplantation; 2. Types of transplantation; 3. HLA matching in allogeneic transplantation; 4. Stem cell source; 5. Pre-transplant evaluation and counselling of patient and donor; 6. Conditioning regimens; 7. Stem cell infusion; 8. ABO compatibility; 9. Engraftment; 10. Preventative care; 11. Transplant-related complications; 12. Overview of acute and chronic graft-versus-host disease; 13. Acute graft-versus-host disease and staging; 14. Graft-versus-host prophylactic regimens; 15. Treatment guidelines for acute graft-versus-host disease; 16. Chronic graft-versus-host disease; 17. Engraftment syndrome; 18. Infectious disease; 19. Graft rejection and failure; 20. Gastrointestinal complications; 21. Oral health in stem cell transplantation; 22. Pulmonary complications; 23. Veno-occlusive disease; 24. Special transfusion-related situations; 25. Cardiovascular complications; 26. Neurologic complications; 27. Cystitis; 28. Donor lymphocyte infusion; 29. Transplantation: regulation and accreditation; Index.
£999.99
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 107
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapter One reviews the antitumor effecrs of lithium carbonate. Chapter Two analyses the current evidence on the role of epigenetic mechanisms involved in the progression of various types of cancer and their clinical relevance. Chapter Three examines pregnancy and hemodialysis. Chapter Four focuses on the pharmacokinetics, efficacy and safety of levonorgestrel. Chapter Five discusses challenges and management of childhood obesity in the United Kingdom. Chapter Six reviews dynamic and integrated synaptic processing in sex-steroid sensitive medial amygdala of female rats. Chapter Seven studies the characterization of anti-coxsackie virus B3 constituents of Scabiosa arenaria Forssk by reversed phase-high-performance liquid chromatography. Chapter Eight provides a review of risk factors, diagnosis and management of congenital upper limb anomalies. Chapter Nine summarizes the current knowledge on genetics, environmental factors, clinical characteristics, medical, laser and surgical treatment options of exfoliation syndrome and exfoliative glaucoma.
£163.19
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 109
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapter One reviews sialic acids in early life and their impact beyond infancy. Chapter Two examines how prolonged excitation of hypothlamic sympathetic center provokes preeclampsia by the stimulation of expanded pregnant uterus through uterus-brain nerve. Chapter Three reviews the genesis of the new and emerging field of synthetic biology. Chapter Four studies individuals'' involvement in biobanking and new ways of doing research in bio-medicine. Chapter Five discusses the impact of IgG4-related sclerosing cholangitis after hepato-biliary-pancreatic resection in our population and identifies non-invasive diagnostic methods, IgG-IgG4 serum values, and magnetic resonance cholangiography (MRC) images to diagnose this entity in the early postoperative period in order to avoid aggressive and unnecessary treatment. Chapter Six examines and summarizes the available literature on burnout amongst emergency medicine physicians and provides recommendations for future work in this field. Chapter Seven provides microbiological and physicochemical characterizations of ground and spring waters associated with public health issues. Chapter Eight examines how abdominal vagal afferent nerves could be activated by nutrients and hormones via the mechanisms of molecular sensing, signal transduction and sensing regions and how they regulate food intake and metabolism. Chapter Nine discusses the major musculoskeletal manifestations found in diabetes mellitus. Chapter Ten elucidates important basic and clinical aspects of malignant otitis externa (MOE) and outlines an updated diagnostic workup and management of MOE in a clear and concise manner.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 110
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapter One reviews parkin and other proteins of Parkinson''s Disease. Chapter Two discusses hyperlipidemia, its impact on the development of cardiovascular disease (CVD), and the use of statins, as well as both yeast polysaccharides and other miscellaneous newer and investigational non-statin agents, to treat hyperlipidemia. Chapter Three summarises the concept, pathogenesis, variables and treatment of mitochondrial dysfunction in severe hemorrhagic shock. Chapter Four reviews use of telomerase-targeted replicative adenoviruses for cancer treatment and diagnosis. Chapter Five evaluates the swelling and diffusional behavior of guar gum for the controlled release of bioactive agents. Chapter Six reviews both in vitro and in vivo studies that were carried out to check the activity of phytoestrogens used in topical products. Chapter Seven presents the potential application of phytoestrogens to alleviate the symptoms of climacteric. Chapter Eight provides preventive measure of developing osteonecrosis of the jaw in patients receiving bisphophonate therapy. Chapter Nine investigates the possible mechanisms of the protective effect of glutamine on animal models and its use in the clinic. Chapter Ten presents relevant features of the glutamine role in immune pathways, energy metabolism and exercise, highlighting the relationships between glutamine supplementation and performance in adult subjects with different levels of activity.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 111
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapters One and Two review the clinical uses, functionality, mechanisms of action and adverse reactions of Andrographis Paniculata. Chapter Three gives an overview of the chemical structure and biosynthesis of triacylglycerols in vegetables, and their health benefits. Chapter Four discusses long-chain fatty acids in triacylglycerol stores and physical performance. Chapter Five presents the different methods for determining skin color. Chapter Six discusses the imaging of chronic pancreatitis. Chapter Seven examines the influence of gingivitis on abdominal aortic aneurysms. Chapter Eight provides a review of the existing research on measurement, rates, correlates, and consequences of sedentary behavior in Multiple Sclerosis. Chapter Nine focuses on injury and recovery of the periodontal ligament.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 112
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapters One describes the oxidative stress in disease and health, as well as the action of classic and new antioxidants. Chapter Two examines an investigation by big data analysis of the Urban Heat Island (UHI) effect on human health problems. Chapter Three provides a literature review of the associations between sedentary behaviour and health-related outcomes in Japan. Chapter Four assesses non-specific chronic low back pain and reviews management strategies. Chapter Five studies scleroderma and its mythological background. Chapter Six reviews the possible mechanisms of 5-HT and their metabolites as common protectors against oxidative stress produced by animal venoms. Chapter Seven focuses on the effect of broad bean true mosaic virus (BBTMV) and salicylic acid (SA) treatments on the concentrations of photosynthetic pigments, total phenolics content, protein contents and the yield of susceptible and tolerance broad bean cultivars. Chapter Eight reviews the photochemical (photooxidative) activity of xanthone itself and the preventive effect of xanthone derivatives on photosensitised DNA damage.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 113
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapters One reviews the epidemiology and molecular mechanisms of hepatocellular carcinoma, as well as methods for its diagnosis and treatments with a special emphasis on the latest advances. Chapter Two examines in vitro anti-cancer actions of progesterone on human melanoma cells based on recovery cell growth, adhesion and migration functions. Chapter Three reviews the medical uses, potential complications and advances in spinal anesthesia for ambulatory surgery. Chapter Four evaluates the effects of low dose spinal anesthesia on vital signs of patients for Cesarean Section (CS) and fracture repair. Chapter Five discusses Horner''s syndrome after spinal and epidural anesthesia. Chapter Six studies the chronobiology and electrophysiology of the rat heart under pentobarbital anesthesia. Chapter Seven provides literature orientation and personal experiences to discuss patient-specific instrumentation of total knee arthroplasty. Chapter Eight reviews the involvement of the endocrine system in the pathogenesis and clinical course of Ménières disease. Chapter Nine summarises recent research reporting several different effects of non-gluten members of the α-amylase/trypsin inhibitors and other nutritional food ingredients on the onset and severity of innate and/or adaptive immune responses.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 115
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapters One studies Kleine-Levin syndrome. Chapter Two reviews stress, hypothalamicpituitaryadrenal dysfunction, inflammation, and psychomotor disability in preterm birth infants. Chapter Three discusses the cellular and molecular basis of fibrogenesis. Chapter Four examines the role of ocular melanin, melanosomes and melanocytes in eye functionality. Chapter Five focuses on hypopituitarism especially on the clinical feature, pathogenesis, and treatment of these novel conditions of hypophysitis. Chapter Six discusses benign and malignant anorectal pathology. Chapter Seven analyses the medical and surgical management of haemorrhoids. Chapter Eight introduces and reviews computer aided drug designing. Chapter Nine discusses the occurrence and risk assessment of organochlorine pesticides in seafood. Chapter Ten gathers and describes information about trans fats and their regulation in Mexico in over the last ten years. Chapter Eleven analyses the legislation, consumption and potential replacement solutions of trans fat in Argentina.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 117
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapters One discusses the utility of negative pressure therapy in the treatment of chronic resistant venous ulceration by reviewing the current available literature on this topic. Chapter Two reviews telemedicine in chronic respiratory diseases. Chapter Three focuses on the role of GABA/glycine in respiratory network formulation using knock-out mice with respiratory failure. Chapter Four investigates in vitro and in vivo studies of prolonged dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) treatment. Chapter Five analyses superparamagnetic iron oxide nanoparticles (SPIONs) based magnetic hypothermia as a promising therapy in cancer treatment. Finally, Chapters Six and Seven discuss the prevalence, risk factors, potential complications, and psychological impacts of miscarriage and perinatal mortality.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 118
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapters One researches recent topics in retinal ganglion cells. Chapter Two provides a review of acetylsalicylic acid resistance. Chapter Three analyses the effect of chlorogenic acid (CGA) on myocardial diseases. Chapter Four focuses on the role of diet in the composition and activity of gut microbiota. Chapter Five examines data on the Maillard reaction as a cause of stochastic damage in E. coli, and subsequently, of E. coli aging. Chapter Six studies haploinsufficient tumor suppressor genes. Chapter Seven discusses animal models of respiratory distress in neonates. Chapter Eight presents professional training in the work-up of bleeding disorders in women. Chapter Nine investigates microbial dynamics characterisation during the composting process of organic wastes.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 119
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapters One describes the prevalence, anticipated risk factors and potential complications related to ectopic pregnancies. Chapter Two reviews the mechanism participating in altered glucocorticoid sensitivity that in turn affects their effect on immune response. Chapter Three analyzes the usefulness of an initial intravenous immunoglobulin therapy with a delayed use of anti-inflammatory drugs for Kawasaki disease. Chapter Four focuses on the formation, metabolism and role in diabetic vascular complications that glycation end products have. Chapter Five highlights the applications of analytical methods in the determination of fluoroquinolones in pharmaceutical or biological material and in the degraded solutions. Chapter Six describes the in silico characterization of carvacrol and its derivatives in order to determine the physicochemical, topological and quantum mechanical properties that promote their antibacterial activity. Chapter Seven studies the CTHRC1 as a pituitary hormone. Chapter Eight discusses nitric oxide and abdominal aortic aneurysms. Chapter Nine provides an overview of cloud point extraction of parabens from water samples. Chapter Ten reviews past and current state of Pacific sleeper shark abundance in the North Pacific, discusses its deterrence aspects for fisheries and proposes some ways of commercial exploitation of the stocks of this shark.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 120
Book SynopsisThe chapters in this volume present the latest developments in medicine and biology. Chapters One begins with a review of the clinical aspects, side effects and potential complications of intrauterine devices (IUD). Chapter Two analyzes new strategies to reduce the burst release effect of copper-based IUDs. Chapter Three discusses ubiquitin-conjugating enzymes. Chapter Four provides some advanced research and treatment methods in the enhancement of innate immune response to prevent infections or infections leading to diseases. Chapter Five focuses on Basiliximab. Chapter Six studies bismuth ions, gastrins, and their biological activity in the gastrointestinal tract. Chapter Seven analyzes the risks and benefits of the barium enema. Chapter Eight investigates the complications caused by ventilation in patients with acute respiratory distress syndrome. Chapter Nine includes a critical discussion on the management of a quadricep hematoma from acute injury to the end stage of rehabilitation. The final chapter provides an updated review on the mechanisms linking obesity with inflammation, and analyzes the importance of inflammatory biomarkers such as TNF-alpha, IL-6, C-reactive protein and Ceruloplasmin as connecting links between inflammation, obesity and associated complications.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 121
Book SynopsisChapter One examines what has been learned about the Nipah Virus, a highly lethal paramyxovirus, throughout the nearly two decades since its discovery. The authors review includes progress in the understanding of its molecular characteristics, its pathogenesis in humans and animal models, transmission and prevention of infection, the development of experimental vaccines and therapeutics, and the relationship with its pteropid bat hosts. Chapter Two covers Bursitis, a characteristic feature of polymyalgia rheumatic (PMR), which is a common inflammatory rheumatic disease of people aged 50 and above, with pain and stiffness in the shoulder girdle and often pelvic girdle and neck. Although local musculoskeletal signs and symptoms are the hallmark of the disease, PMR is a systemic inflammation. The authors discuss how weekly bilateral shoulder corticosteroid injections have been studied, and their efficacy and safety have been proved, but oral cortiocosteroids still remain the cornerstone of therapy. Chapter Three reviews fetal sinus bradycardia, a condition defined by a heart rate less than 100 bpm. The author give an overview of the current diagnostic techniques, prognosis and treatment strategies. Mechanical stress on heart, caused by volume overload alone, is considered to be the condition that regulates the synthesis and release of natriuretic peptides. Thirty years later the measurements of the peptides, especially NT-proBNP, has not met all of the expectations of a simple and useful tool in cardiology; the mechanical stress on the heart does not explain all of the findings made in clinical studies. In Chapter Four, a hypothesis is presented in which the oxygen metabolism is in the focus. Chapter Five discusses how red light stimulated the phosphorylation of two small proteins, transit peptide NDPK2 and pre-sequence NDPK3 in etiolated pea seedling stems. In human NDPKs, Nm23H1 and Nm23H2 may function to reduce the influx of singlet oxygen and suppress tumor metastasis. Chapter Six offers several easy exercises that can be used as postoperative therapy for carpal tunel sydnrome, or as preventative measures for people with a heightened risk of developing the syndrome. The theory behind the load cell is presented both for conventional-socket transtibial amputees and osseo-integrated transfemoral amputees in Chapter Seven. Examples of equipment used on osseo-integrated transfemoral amputees is also shown. Studies and outcomes for a transtibial and a transfemoral osseo-integrated prosthesis are given, including force-moment analysis. In Chapter Eight, the relationship of catalase activity, Cdk5 regulation of topographic neuronal architecture, and cross-talk are discussed.
£205.59
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 122
Book SynopsisChapter One deals with the structural and developmental aspects of bacterial biofilms; the problems associated with biofilm formation and current control strategies utilised in clinical and industrial sectors; and the advances regarding the use of compounds derived from plants to control the formation of biofilms at the different stages of development. Chapter Two discusses how the current antibiotic crisis has made understanding bacterial cellular metabolism essential for improving existing therapies and identifying novel therapeutic approaches. Bactericidal agents have been reported targeting the cytoplasmic membrane, DNA, RNA, protein synthesis, and cell wall synthesis. In Chapter Three, a revision of the studies concerning the effect of bariatric surgery procedures in overall oral food perception is made, discussing how this may influence choices and dietary behaviour. Chapter Four provides a review of studies of taxeme-induced peripheral neurotoxicity (TIPN) and discusses challenge for TIPN areas. Chapter Five identifies surrogate markers for predicting the long-term prognosis and biochemical response to ursodeoxycholic acid (UDCA) in patients with primary biliary cholangitis (PBC). Chapter Six broadly covers IgG4- related disease (IgG4 RD), a constellation of disorders united by histopathological and immunohistochemical analysis. Classically, IgG4 RD has been associated with gastrointestinal (GI) tract, especially the pancreas and often patients present with repeated bouts of pancreatitis. Chapter Seven discusses the use of Retinol, a monoaromatic compound of vitamin A, for the treatment of wrinkles, fine lines, changes in microrelief and anti-aging effects. Chapter Eight identifies factors that protect an individual from developing a whiplash injury after a road traffic incident and looks at demographic variations rendering a person more likely to suffer a whiplash.
£205.59
Nova Science Publishers Inc Advances in Medicine and Biology: Volume 126
Book SynopsisAdvances in Medicine and Biology. Volume 126 opens with a discussion on fungal infections of the central nervous system and the way they have been known to parallel the incidence of systemic fungal infections in at risk populations. The reported percentages of central nervous system involvement associated with invasive fungal infections range from 3% - 100% depending on the species isolated. Next, the authors discuss the effect of agouti-related peptide on the increase of food intake and body weight in animal models of cachexia, proposing agouti-related peptide as a possible anti-anorexigenic drug. This compilation includes the first complete overview of human leukocyte antigen variation across Austronesian populations and includes the effects of admixture along the migration path during their 5,000 year diaspora. The authors conclude that intermarriage has shifted allele frequencies in migrant peoples from those found in their original pure Austronesian stock (Taiwanese natives) towards those populations with which they have since become blended. Following this, a review of the factors affecting the photodegradation reaction and mechanism of riboflavin and related compounds is provided. Riboflavin belongs to the family of vitamin B complex and is present in a number of food products. Additionally, this book addresses the determination that the existence of the majority of microorganisms in the form of three-dimensional associates on the phase interface proves the significant survivable advantages as compare with selective ones. Afterwards, the authors present their designed dimeric dipeptide called GK-2 (bis(N-succinyl-Lglutamyl-L-lysine)hexametylendiamide) on the base of a beta-turn sequence of NGF loop4, which is most exposed to solvent and hence has a significant role in the interaction of NGF with the receptor. Later, the authors analyzed the pharmacological properties of the GlyR in the immature retina and compare those with the adult. Membranes from adult and immature rat retinas were incubated under different conditions in the presence of radioactive glycine or strychnine. Radioactive binding was considered as the specific binding to the GlyR. The closing chapter discusses Professor Werner Kalow (1917-2008), a pioneer in the field of pharmacogenetics/pharmacogenomics, foreseeing future emerging subspecialties such as pharmacoepigenetics/pharmacoepigenomics and pharmacoanthropology. All these disciplines study human individuality and variability, paving the way for a translational personalized medicine. However, they cannot be legitimate if not properly founded by a broader, coherently unified science which deals with method and principles.
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Nova Science Publishers Inc Advances in Health and Disease: Volume 3
Book SynopsisIn this compilation, the authors begin by examining the correlation between stress tolerance, metabolism, and energy balance using insects as model systems and demonstrate how in recent years, we have learned mostly from physiological responses in insects that many parallels exist between invertebrate and mammalian homeostasis. Therefore, studying insects as simpler model organisms can provide useful information for elucidating the complexities of mammalian metabolism. Following this, the book presents a mixed-methods study with the goal of adding to the existing body of knowledge in the areas of HIV-related risk behaviors, HIV testing behaviors, and the various factors that act as barriers and facilitators to HIV testing among Asian Americans and Pacific Islanders. The authors go on to deliberate on the advantages and disadvantages of potential strategies for the treatment of mitochondrial diseases caused by mutant mtDNA. As cells contain multiple copies of mtDNA, pathogenic mtDNA mutations frequently coexist with wild-type mtDNA, a phenomenon known as heteroplasmy. The patient attachment style is investigated as a moderator of the patient and practitioner relationship in order to potentially promote clinical interventions aimed to enhance the adherence to medical care, improving health-care outcomes and patient quality of life. Next, the patterns of dislocation and subluxation are reviewed, along with associated issues, in order to allow surgeons to provide optimal care for these patients. Hip dislocation or subluxation may occur after surgical procedure and has been reported after hip arthroscopy and other open procedures. The authors discuss Castlemans disease, a rare lymphoproliferative syndrome derived into two groups: unicentric and multicentric. Unicentric Castlemans disease is presented as an isolated mass, such as mediastitial lymph node, and is curable with surgery in most cases. Multicentric Castlemans diseaseis comprised of heterogeneous disorders with various etiologies and represents systemic inflammatory symptoms, such as fever and weight loss. The subsequent chapter discusses the evidence concerning the involvement of microbiota on the appearance and development of inflammatory bowel diseases and the eventual response to medical treatment. Despite promising links between microbial composition and disease phenotypes, to date no causative role for the microbiome has been established, and our understanding of the dynamic role of the human microbiome in inflammatory bowel diseases remains incomplete. The book also examines sudden death, an unexpected event that happens in healthy people or in stable patients. It must occur within one hour from the onset of the first symptoms, and it is precipitated by a cardiac arrest, which is irreversible due to the absence of adequate assistance. In closing, amantadine is examined in the context of treatment of Parkinson''s disease and its complications. As a tricyclic amine, it enhances the release of dopamine at the synaptic cleft and inhibits its uptake, acts directly at the D2 receptor and up-regulates it, has anti-muscarinic properties, and non-competitive antagonism of the NMDA receptor. It has been studied as both a monotherapy or adjuvant therapy for Parkinson''s disease with mixed results.
£205.59
Nova Science Publishers Inc Advances in Medicine and Biology. Volume 127
Book SynopsisIn Advances in Medicine and Biology. Volume 127, the authors discuss Parkinson''s disease (PD), a neurological disorder characterized by the death of dopaminergic neurons in the substantia nigra pars compacta and reduced dopamine levels in the striatum. Currently, there are few pharmacological treatments for PD and although Levodopa has frequently been used, it is not a viable treatment option for all patients. Thus, this book presents experimental evidence supporting the claim that endocannabinoid signaling may represent a promising therapeutic target for PD, inducing a reduction in neurodegeneration with minimal psychotropic effects. Subsequently, it presents findings that free-hydroxyproline observed in a physiological system must be resulted from a degradation of protein molecules. Variations in free-hydroxyproline concentrations in the plasma and white muscle of fishes, with genetic differences in growth rates and with different feedings, could indicate differences in protein degradation rates for tissue remodeling and growth. Since the synthesis of the connective tissue framework of muscle is a rate-limiting step in muscle growth, the concentrations of white muscle free-hydroxyproline could be reliable for growth studies, as its levels are correlated with fish specific growth rates (SGR) and feed efficiency. Next, the authors analyze the results of umbilical hernia repair using Ventralex Hernia Patch, a bilayer prosthesis. Preoperative characteristics, surgical procedure details, postoperative complications and recurrence rate were studied. An overview of the most up-to-date findings on the association of NGF with development of schizophrenia is presented, based on literature data as well as the authors own findings. The contributions of other research groups are provided and discussed in the context of prominent existing hypothesis of psychiatric disorder development. Afterwards, hernias are discussed as one of the most common reasons a primary care patient may need referral for surgical intervention. The emergence of next-generation prosthesis seeks to achieve the best possible integration into the tissues, improving their performance on all interfaces and avoiding complications. The authors exhibit a retrospective cohort study to assess the impact of 6-hour versus 4-hour HD sessions in end-stage renal disease (ESRD) patients treated with three times per week, daytime, in-center HD. Using data from a cohort of forty-three, stable chronic ESRD patients, the authors compared twenty-one patients undergoing 6-hour HD sessions with twenty-two patients on conventional 4-hour HD sessions. The following chapter begins with an introduction to collagen and the function of Hyp in the collagen molecule, followed by a description of sources of various Hyp fractions in tissues and body fluids. The effects of different toxins on various Hyp fractions in the serum and tissues are also discussed. Then, soy isoflavones or soy derivatives (supplements containing S-equol) are recommended for relieving vasomotor symptoms. The evidences for standardized cohosh preparations are effective and are also be recommended. This book also discusses DNA damage repair, a very important biological process commonly associated with human health and diseases, because a detailed elucidation of DNA repair mechanism is essential for a better understanding of health and disease. Afterwards, the current information on collagen PTMs and their alteration under different pathological conditions are examined. It has been reported that collagen undergoes polyubiquitination in response to S-adenosyl-L-methionine. The polyubiquitination inhibits Collagen processing leading to decreased collagen secretion in hepatic stellate cells (HSCs). In closing, a critical review about the impact of changes in lifestyle and diet supplementation with natural phytochemicals on cancer statistics is given. This review highlights the new advances in understanding the anticancer activity of flavonoids based on its ability to damage DNA in cancer cells.
£205.59
Nova Science Publishers Inc Advances in Medicine and Biology. Volume 128
Book SynopsisIn Advances in Medicine and Biology. Volume 128, the authors provide evidence that several families of GPCRs dynamically modulate microglial phenotypes and provide evidence that aberrations in G-protein coupled receptors-mediated signaling are prime contributors to a loss of homeostatic microglia states. A comprehensive landscape on the physiological conditions already known to be important for dendritic cell (DC) differentiation is included. Specifically: presenting stages of development of bone marrow stem cells; comparing the ontogeny of DCs in mice and humans; debating the differences between conventional DCs versus plasmacytoid DCs; highlighting that Langerhans cells (LCs) have different origins; discussing factors that may modulate the development of DC subsets; and emphasizing ontogenetic properties of DCs that make them different from monocytes and macrophages. Next, the authors review ex vivo and in vitro studies about the effects of human soluble fibrinogen molecule on blood components behavior and its effects at physiological and pathophysiological conditions, as well as in vitro studies conducted in experimental animal models. The tacrolimus (TAC) metabolism is reviewed in a separate study which proposes the TAC metabolism rate (C/D ratio) as a novel tool to assist physicians in risk stratification to individualize therapy in patients after (renal) transplantation. Continuing, the book postulates that modulation of nitric oxide (NO) concentrations at the maternal-fetal interface is relevant for maintaining early gestation due to failures in vascular adaptations. NO regulates vascular tone, angiogenesis, and cellular aggregation and adhesion, which are important functions in establishing and maintaining normal pregnancy. This book also presents the research and development of a collaborative, social-networked approach to train elementary and middle-school students so that the students can be aware of their bad sitting posture and timely improve it. Results show that the proposed approach and the developed posture training tools were very effective in improving teens posture.
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Nova Science Publishers Inc An Essential Guide to Mens and Womens Health
Book Synopsismen. Topics include: the epidemiology and temporal trends of low bone mass, osteoporosis and related fractures; the morbidity and mortality associated with osteoporosis and osteoporotic fractures; low bone mass risk factors and etiology; and osteoporotic risk assessment. The book includes a study with the goal of understanding workers social representation of occupational risks and preventive measures. A qualitative approach was utilised based on social representation theory processual approach. The sample was comprised of male workers from a municipal service responsible for cleaning and conservation of the public area with no permanent contract in a large city in the South-eastern region of Brazil. The authors describe working conditions and health conditions of men from small enterprises in Campinas Fruit and Vegetables Warehouse Wholesale. A cross-sectional study with a sample of 200 male workers was developed. Data collection was performed using the following instruments: questionnaire with socio-demographic data, lifestyle, health and work aspects, QSETES elaborated on by author Monteiro and a stress scale adapted by Monteiro based on Elo et al. The authors study the status of women in India, arguing that many poor health outcomes of girls and women can be attributed to their low rank in society. Specifically, the focus is on female economic devaluation, specifically dowry, an issue with historical antecedents that has failed to be addressed or even exacerbated by the entry of the country into the global economy. Postpartum hemorrhage (PPH) is examined as one of the worlds leading causes of maternal mortality. Various conservative surgical procedures have been developed in recent years to reduce the need for hysterectomy, including external compression sutures, selective de-vascularization by surgical ligation or radiological embolization of the uterine and pelvic arteries and intrauterine balloon tamponade. The authors also examine the correlation between the development of congenital malformations and teratogenesis brought on by adverse conditions within the millieur interieur of the developing embryo, suggesting that the pharmacokinetic processes must be seen in the perspective of maternal and fetal lethal dose parameters. A study on perceived motives for contraceptive interference (CI) is included, hypothesizing that common barriers to male condom use might also be perceived as motives for CI enacted by a man toward his female partner.
£92.79
Nova Science Publishers Inc Advances in Medicine and Biology: Volume 130
Book SynopsisAdvances in Medicine and Biology. Volume 130 begins by discussing proton pump inhibitors (patented in 1979) that selectively target the H,K- ATPase of gastric parietal cells as a reliable therapeutic regimen for management of acid reflux disease and gastric bleeding. Around the same time, H. pylori was recognized as the main cause of peptic ulcer. The following chapter explores how common bile duct stones can be predicted and investigated. In addition, the management of proven ductal calculi is discussed in the preoperative, intraoperative and postoperative stages. The investigation of ductal stones is partly dependent upon patient presentation and liver function tests, but also on availability of imaging modality and surgical experience. Afterwards, the authors summarize the current knowledge regarding the toxic effects of STZ on mammalian DNA and chromosomes, putting emphasis on the most recent findings on this subject. At the chromosome level, STZ induces chromosomal aberrations (including those ones involving telomeric sequences), micronuclei and sister chromatid exchanges. A review of current state of knowledge of atmospheric parameters pathophysiological mechanisms and its cardiovascular risk effects is included. Additionally, some medical prevention strategies that can provide effective protection against the negative health effects of global climate change are presented. The authors go on to summarize the morphogenesis, 3D structure, and rearrangement of the IHBDs, as well as the cellular changes of cholangiocytes during development and regeneration. Recent advances based on gene targeting, lineage tracing, and threedimensional (3D) analysis of the liver tissue have improved our understanding of the IHBDs morphogenesis and regeneration. The goal of the concluding chapter is to describe the current educational preparation and scope of practice of pediatric advance practice providers (APPs) and provide guidelines with a new practice model as to how to successfully integrate APPs into the pediatric emergency department. The pediatric health care and role of an acute care APP has evolved significantly in the last few years, with APPs seeing patients ranging from non-urgent to all kinds of pediatric emergencies.
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Nova Science Publishers Inc Advances in Medicine and Biology: Volume 132
Book SynopsisBiofilms are complex and dynamic communities of surface-attached microorganisms held together by a self-produced extracellular polymeric matrix, forming a highly hydrated structure. It is known that there is considerable heterogeneity within biofilms with respect to local environments, which may result in spatial and temporal patterns of gene expression. Advances in Medicine and Biology. Volume 132 begins by discussing the use of GFP to explore these microbial communities, presenting the most recent developments associated with GFP variants and novel applications of this molecule in biofilm research. Next, the authors discuss the fibrinolytic and its important role in reproduction. Plasminogen Activator Inhibitor-1 (PAI-1) is one of the primary regulators of the fibrinolytic system and is expressed in various cells including ovarian granulosa and theca cells, endometrial cells and trophoblasts. This overview provides the current knowledge on the role of PAI-1 and PAI-1 gene mutations in reproduction. Green fluorescent protein (GFP) is a bio-luminous fluorescent phosphoprotein which was originally isolated from the luminous organ of the jellyfish Aequorea Victoria. At the molecular level, it is composed of 238 amino acids with an approximate molecular weight of about 27 kDa. The authors discuss the role of GFP in animal diagnostic technologies, molecular tracking techniques using GFP as fusion tags in studying proteinprotein interactions and real time monitoring of host pathogen interactions. In the authors Immunoallergology Department, a recent study of 64 CSU patients treated with omalizumab provided pertinent information. Overall, the patients had a reduction of the UAS7 score of 5.82% per omalizumab administration (pOa) and of the DLQI score of 6.69% pOa (data not published). However, when patients were divided according to their baseline serum total IgE levels (STIgE), patients with higher STIgE had a much faster response to omalizumab. The results of this study are discussed in detail. The subsequent chapter aims to explore the diagnosis and management of gastrointestinal stromal tumours (GISTs) that arise from the small bowel in both metastatic and non-metastatic disease. GISTs account for two per cent of all neoplasia of the gastrointestinal tract. They represent the most common GI mesenchymal tumour with a worldwide incidence of 11-15 per million and a median age of presentation of 55-60 years. Diabetes insipidus (DI) is examined as one of the major clinical syndromes characterized by the excretion of copious volumes of diluted urine (polyuria) together with persistent intake of abnormally large volumes of fluid (polydipsia). Investigation of the chronological changes of hyper intensity (HI) distribution over the pituitary stalk and the posterior lobe after transsphenoidal surgery on MR images might enable to predict how frequently postoperative diabetes insipidus occurs and how long it persists, and to elucidate an underlying mechanism for the appearance of the HI in the pituitary stalk. In the following chapter, the authors discuss salient aspects of central nervous system effects of methionine and methionine metabolites in relation to behavioural, neurochemical and possible structural alterations. The possibility of the evolution of conventionally-approved clinical applications of oral methionine, and the potential limitations to its utilisation in such capacity are also considered. Later, this collection considers the functions of Gamma-Aminobutyric acid (GABA) in pharmacology and diseases. The authors aim to address what GABA is, how GABA reacts, and what GABA-related diseases and agents exist. GABA is the principal inhibitory neurotransmitter of the vertebrate central nervous system, acting at inhibitory synapses in the brain. In the concluding chapter, the authors address how gabapentin, a synthetic analog of GABA, may be an effective analgesic used to treat different types of neuropathic pain syndromes, including diabetic neuropathy, postherpetic neuralgia, trigeminal neuralgia, painful neuropathy resulting from HIV infection, cancer pain, fibromyalgia, pain after burn injury, and complex regional pain syndrome.
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Nova Science Publishers Inc Advances in Medicine and Biology: Volume 133
Book SynopsisThe management of psoriatic arthritis (PsA) is complex and early intervention is needed to prevent or delay the progression of the disease. The severity of PsA and response to medication should guide the proper treatment modality, as per the recent EULAR and GRAPPA recommendations. In this collection, the authors begin by examining conventional treatment options include non-steroidal anti-inflammatory drugs (NSAIDs) and disease modifying anti-rheumatic drugs. Next, the authors examine parasitic nematodes which cause substantial production losses in grazing animals and suffering in humans. Farmers treat animals with anthelmintics, often in an unplanned way. Frequent whole flock and herd treatments have encouraged the development of resistance as all worms in the animals are exposed to anthelmintic. The single largest problem with anthelmintic resistance is persuading farmers to adopt strategies that slow the development and spread of resistance. The authors go on to discuss the role of green fluorescent protein (GFP) in animal diagnostic technologies, molecular tracking techniques using GFP as fusion tags in studying proteinprotein interactions and real time monitoring of host pathogen interactions, as reporter tags in animal viral studies, in in-vitro and in-vivo imaging of transgenic animals for genetic screening and in animal marker vaccines and cancer studies. Following this, the authors provide their understanding of pathogenesis in spinal cord injury (SCI), the current therapeutic efforts and their limitations, and the emerging roles of retinoids in neuroprotection and functional recovery in SCI. Retinoids use retinoic acid receptor (RAR) and retinoid X receptor (RXR) in the cells for modulation of expression of genes that eventually provide neuroprotection in SC. Pap smears detect cytologic abnormalities that indicate the possible presence of a pre-malignant lesion. The cytologic suspicion of a high grade lesion presents the risk of hiding a more severe dysplasia, which has a high risk of progression to invasive neoplastic lesion. Thus, the authors propose that adequate treatment and follow-up should be offered, such as cytology repeat, HPV testing, colposcopy, colposcopy-directed biopsy, or excision of the transformation zone. The subsequent chapter deals with the criteria that can be leant upon to prescribe retinoids for the off-label treatment of dermatological diseases. Exemplary clinical cases are illustrated. The author hopes to inspire creative physicians, and revamp classical, time-honored therapeutic methodologies as well. This book also discusses methods to study bacterial heterogeneity and its influence on phenotypic drug resistance include flow cytometry based approaches, RNA sequencing techniques, microfluidic technology time-lapse microscopy and mass spectrometry-based proteomic approaches. These technological advances are powerful tools that enable us to explore and interrogate mechanisms of bacterial heterogeneity in pathogen populations. Lastly, the authors review the effects of how reproductive toxic exposures induce apoptosis of male germ cells by affecting the spermatogenic cells of the developing testis and investigate several possible mechanisms underlying alkylating agent-induced reproductive toxicity. Furthermore, an understanding of how cells cope with DNA damage caused by alkylating agents is valuable in clinical medicine.
£205.59
Nova Science Publishers Inc Advances in Medicine and Biology: Volume 134
Book SynopsisThe eyes are highly diversified photosensitive structures. In all vertebrates, eyes resemble in molecular composition and are predominantly composed of extracellular matrix (ECM). Advances in Medicine and Biology. Volume 134 explores the dual role of ECM in ocular homeostasis and diseases and discusses how this duality can be used to treat such diseases. The view on ECM biology offered by this work is translational and adress concepts of basic science and clinical-surgical issues.Following this, the authors aim to provide information about the mechanisms of oxidative stress-mediated apoptosis, to provide updates for previous studies update and some of the current paradigms discussed and to provide a basis for future studies. This review highlights the elementary value of apoptosis, including its effect on tissue homeostasis and cellular stress.The aim of the subsequent study was to investigate microcirculation peculiarities of the covering tissues of the limbs and body in patients with orthopedic pathology and in track-and-field athletes having reached high sport mastership.Spontaneous cerebrospinal fluid (CSF) leaks are a clinical entity in which CSF rhinorrhea occurs in the absence of any inciting event. Spontaneous CSF leaks are associated with elevated intracranial pressure (ICP) or underlying idiopathic intracranial hypertension (IIH). The authors report on a cohort of patients who have undergone nasal endoscopic repair for spontaneous CSF leaks.Wound healing is a widespread feature of multicellular organisms. Evidence illustrates that apoptosis has very important roles in the various phases of the wound healing process. As such, the authors maintain the importance of keeping up-to-date with studies on apoptosis and its associated mechanisms highlighted in the wound healing process, providing a systematic analysis of recent molecular research in wound healing applications.Despite enormous improvements in supportive and standard care, septic shock and liver failure remain major causes of morbidity and mortality in critically ill patients. Plasma separation via centrifugation is a common method for therapeutic plasma exchange in patients with liver failure and septic shock. The authors suggest that the use of a centrifugal approach rather than regular plasma filtration enables the transfer of larger particles into the resulting plasma fraction. The possible advantages of using centrifugation in comparison to hemofiltration in blood cleaning techniques are currently hypothetical.The most commonly used staging classification of the classical form of Kaposis sarcoma was presented by Brambilla et al. in 2003. The authors distinguished four stages of the disease based on the morphology of the cutaneous lesions, location of the skin changes, presence of complications and internal organ involvement. The clinical presentation, diagnosis and management of classical Kaposis sarcoma will be discussed in the closing chapter.
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Nova Science Publishers Inc Advances in Medicine and Biology: Volume 140
Book SynopsisVolume 140 opens by discussing vascular endothelial growth factor, an attractive target for antiangiogenic therapy for glioblastoma. Although bevacizumab, a humanized anti-vascular endothelial growth factor antibody, improves the progression-free survival of patients with glioblastoma, prolonged overall survival has been attained only in few patients with a proneural type of glioblastoma. As such, bevacizumab is increasingly used to treat newly diagnosed and recurrent glioblastoma. Bevacizumab selectively inhibits glioblastoma growth by targeting membrane-bound vascular endothelial growth factor, inhibiting angiogenesis and thus halting tumor growth. Vascular endothelial growth factor plays a major role in wound healing, with upregulation starting on day three and levels remaining high up to 24 weeks after wound creation. The authors discuss how, to avoid postoperative wound complications following neurosurgical procedures, perioperative management is indispensable. As perioperative preparation, shaving or minimal hair removal should be avoided to prevent minor trauma to the scalp and surgical-site infection. Excess electrocautery coagulation and metal skin clips are efficacious during skin incision for preventing blood loss, but might cause skin edge necrosis and alopecia. Next, the authors briefly summarize the actions of melatonin in a broad range of effects with a significant regulatory influence over many of the protection processes against Fe overload effects. Melatonin is a ubiquitous compound present in bacteria and eukaryotes, which in vertebrates, is released at night from the pineal gland to induce sleep. Quantitative foundations of continuous non-invasive prenatal screening are explored in the following chapter. The mosaicism interval and the interval-based estimate of the degree ofmosaicism are introduced, and the uncertainty of the estimation of the degree of mosaicismcan be quantified by the width of the mosaicism interval. Continuing, the authors emphasize the implication of SRY-related box factors in male sex determination and differentiation, leading to fertility. The production of spermatozoa in adulthood requires a coordination in the regulation of gene expression by a multitude of SRY-related box transcription factors within the testis. The authors perform an overview of the mechanisms of action of SRY-related box transcription factors throughout male development contributing to fertility. The objective of the penultimate study is to evaluate, in vitro, the coagulating, cytotoxic, oxidizing and antioxidant effects caused by the Bothrops jararacussu and B. moojeni crude venoms. The crude venoms protein profiles are characterized, and the biological effects are evaluated and compared between the species. Among the activities triggered by Crotalus durissus terrificus snake venom, coagulation is both intriguing and contradictory since the venom contains in its composition both coagulant and anticoagulant precursor proteins. The concluding work describes the in vitro effects of crude venom and purified proteins from Crotalus durissus terrificus snake venom as they affect coagulation factors of the extrinsic, intrinsic, and common clotting pathways in citrated human plasma.
£177.59
Nova Science Publishers Inc Advances in Medicine and Biology: Volume 144
Book SynopsisThe opening chapter summarises the generation of amniotic fluid, role and its clinical significance of protecting the fetus from external trauma. Next, the role of in silico and in vitro methods are used for the prediction of cytotoxicity which is measured in terms of Selectivity Index or Therapeutic Index, which is defined as the ratio of CC50 and EC50. Additionally the authors discuss the principles of aptamer selection and in vitro applications for bench scientists in molecular imaging, including aptahistochemistry, tissue imaging, enzyme-linked aptamer assay, aptablot, aptamer-mediated flow cytometry and mass cytometry, and super-resolution microscopy. In order for natural rubber latex nanoparticles to be employed in tissue engineering, they need to have designed biological interaction with cells as well as favorable mechanical properties. Cells can delicately sense and respond to external nanoscale features in intricate living systems. With this in mind, chapter four demonstrates an in-depth understanding of how cell differentiation may bring a new perspective to tissue engineering including new bone regeneration and cartilage therapy. In the penultimate chapter, a study of the relationship between the adipokine signaling dysregulation and the androgen status is proposed as necessary to develop new adipokines-based approaches to restore the steroidogenesis and spermatogenesis in male in the metabolic and endocrine diseases. In recent stress research, coping flexibility, which is defined as an individual''s ability to modify their coping strategies effectively according to the demands of different stressful situations, has received considerable attention. The author of the closing chapter presents two cross-sectional studies in order to examine the relationship between insomnia and coping flexibility for daily stress.
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Nova Science Publishers Inc Advances in Medicine and Biology: Volume 145
Book SynopsisThe opening chapter examines the role of different reported oviduct factors in modulating gamete function, fertilisation and early embryo development. The guidelines of occupational post-exposure prophylaxis are reviewed in order to help guide clinicians in managing occupational exposure to human immunodeficiency virus. Next, the authors discuss how the detection of bacterial genes in the genome of eukaryotic cells has provided evidence for gene exchange between bacteria and eukaryotic cells, mainly from bacteria to fungi. The important structural information for potent and selective HDAC3, a zinc-dependent histone deacetylases isoform, inhibitors along with the structure-activity relationships of a handful of molecules may enrich the knowledge of academics and industry personnel. As such, this compilation provides a deep insight into HDAC3 and related inhibitors. In the penultimate chapter, the authors assess the algorithm of cell dead mechanism in spontaneous intracerebral hemorrhage and how the impact of intraperitoneal celecoxib treatment can increase the survival of neural stem cells. The concluding chapter focuses on how foreign protein accumulation in vacuoles proves to be a fruitful production strategy for for biological and industrial enzymes.
£177.59
Nova Science Publishers Inc Health Care in Transition, Volume 1
Book SynopsisHealth care is clearly in transition -- but to where? Managed or unmanaged care? HMO''s or not? Are insurance companies and hospitals the enemy of health care for their own patients? What about the 40,000,000 uninsured in America? Don''t ask the patients, for they have become the ping pong balls in the health care game. This book examines important issues in this ever-growing maze.
£56.94
Nova Science Publishers Inc Health Care in Transition, Volume 2
Book SynopsisHealth care is clearly in transition -- but to where? Managed or unmanaged care? HMO''s or not? Are insurance companies and hospitals the enemy of health care for their own patients? What about the 40,000,000 uninsured in America? Don''t ask the patients, for they have become the ping-pong balls in the health care game. This book examines important issues in this ever-growing maze.
£999.99
ACRES USA INC CANCER NUTRITION HEALING DVDPAL
Book Synopsis
£14.24
Nova Science Publishers Inc Food Allergies: New Research
Book SynopsisA food allergy is an exaggerated immune response triggered by eggs, peanuts, milk, or some other specific food. Normally, your body''s immune system defends against potentially harmful substances, such as bacteria, viruses, and toxins. In some people, an immune response is triggered by a substance that is generally harmless, such as a specific food. The cause of food allergies is not fully understood. A food allergy frequently starts in childhood, but it can begin at any age. Fortunately, many children will outgrow their allergy to milk, egg, wheat, and soy by the time they are 5 years old if they avoid the offending foods when they are young. Allergies to peanuts, tree nuts, and shellfish tend to be lifelong. This book presents recent significant research in this field.
£99.74
Nova Science Publishers Inc Health Issues in Chinese Contexts: Volume 5
Book SynopsisThis is the fifth of sequential collections of the observations and discussions on various health topics in Hong Kong. There are a total of 18 chapters showing some under-discussed health issues both in the Chinese and in the Western contexts. There are several foci of this book: a) anorexia nervosa (AN) in the thick description of the process and outcome of providing family treatment for a Chinese lady and her family, the discussion of anorexia nervosa with morality and social welfare, how medical profession can prevent the development of this illness, a feminist nursing research on AN; b) the gender inquiry of female medical students'' struggle in their studying and profession trajectory in a Chinese society; c) the importance of drug monitoring; d) nursing roles in seasonal flu prevention, gerontological care with a postmodernist lens, leadership and reflectivity practice; e) the needs of family approaches such as the introduction of the proposed Octopus Approach to Family Therapy and family participation in the treatment of obesity of a family member; f)holistic views on disaster management like the tsunami; g) aging related issues such as critical examination on longevity enhancement and social support; h) a discussion on Zombie Films with a health angle; and i) health and beauty products. All the above foci are lack of discussion in Chinese Literature which should be given some attention to enrich our understanding on health from multifaceted lenses.
£176.24
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 17
Book SynopsisThis continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include the effects of hypertension in patients with epistaxis; chronic supportive otitis media in children; the effect of menopausal hormone therapy on breast atrophy; therapeutic targets for Huntington''s Disease; catheter-related infections and mortality from congenital malformations in new-borns and infants.
£162.74
Nova Science Publishers Inc Advances in Medicine & Biology: Volume 18
Book SynopsisThis continuing series gathers and presents original research results on the leading edge of medicine and biology. Each article has been carefully selected in an attempt to present substantial topical data across a broad spectrum. Topics discussed in this compilation include serum ascorbic acid levels in selected surgical diseases; liver transplantation and therapy; background of orthodontic treatment; infectious complications in pregnancy; assessment of child dietary intake and the role of endothelin in regulating neutrophil recruitment to the lungs.
£196.49
