Medical toxicology Books

227 products


  • Taylor & Francis Ltd Reviews in Food and Nutrition Toxicity Volume 4 04

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £56.04

  • Taylor & Francis Ltd Control of Foodborne Microorganisms World of Work

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £56.04

  • Taylor & Francis Ltd Target Organ Toxicity in Marine and Freshwater Teleosts Organs New Perspectives Toxicology and the Environment

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £56.04

  • Taylor & Francis Ltd Ibuprofen A Critical Bibliographic Review

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £56.04

  • Taylor & Francis Ltd Biotechnology And Safety Assessment

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £56.04

  • Taylor & Francis Ltd Total Exposure Health

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £47.49

  • Taylor & Francis Ltd The Charnoly Body

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £43.69

  • Taylor & Francis Kingship and Masculinity in Late Medieval England

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £37.99

  • Taylor & Francis Kingship and Masculinity in Late Medieval England

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £137.75

  • Taylor & Francis StateLed Privatization in China

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £142.50

  • Taylor & Francis Ltd Toxicology of the Human Environment The Critical Role of Free Radicals

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £166.25

  • Taylor & Francis Analytical and Practical Aspects of Drug Testing in Hair

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £175.75

  • Taylor & Francis Ltd The Toxic Microbiome

    15 in stock

    Book SynopsisGut microbiomes are dynamic communities varying from population to population and throughout life. In Western societies, a toxic metabolic shift of gut microbiomes is a driver and underestimated risk factor for the development of many noncommunicable chronic pathologies. This book identifies the root cause of these deleterious microbial changes. During the last several decades, increased consumption of animal products, coinciding and correlating with global climate change, has been a contributing cause of undesirable gut microbiome changes.Key Features Establishes a connection between poor gut microbiome health and chronic disease and cancer development Demonstrates how animal products and low-fiber diet patterns induce a detrimental metabolic transition of the gut microbiome from a human health-maintaining towards a disease-promoting state Discusses the opportunity of a toxic microbial metabolic signatTable of ContentsTable of Contents Dedication Preface Introduction Chapter 1: Diet related chronic diseases are the most critical health problem of modern societies – how did that happen? Chapter 2: The "industrialized" microbiome - a caution label for a global epidemic Missing microbes - does it matter? Chapter 3: The subtle problems of microbiome research Is the microbiome "oversold"? Is microbiome science heading in the wrong direction? Chapter 4: The gut microbiome: a new perspective Our microbiome is a metabolic organ Functional omes: metabolites over species Finding a new definition for a "healthy" microbiome and "dysbiosis" Chapter 5: Shaping the microbial behavior Diet: the master educator of the gut microbiome Starving the microbial self: a foundation for developing a chronic disease Chapter 6: The toxic microbiome "It’s not the fiber, it’s the animal protein" Protein fermentation Fat toxicity Secondary bile acids Heme iron TMAO: the way to a man’s heart is through his gut microbiota Toxicomicrobiomics A toxic microbiome: useful for predicting chronic diseases? Chapter 7: How to build a healthy gut microbiome and prevent chronic diseases The "true" human diet: are humans really omnivores? "The Paleo diet is a myth" Protein concerns: Do we get enough on plants? Feeding microbes for disease prevention and treatment Chapter 8: "Fixing" the microbiome - Can we restore a healthy microbiome by other means than diet? Probiotics – hype or hope? Fecal microbial transplantation or "The Power of Poop" The "Wild West" of microbiome science: drugging the microbiome and personalized nutrition Glossary Abbreviations Literature

    15 in stock

    £39.99

  • Cambridge University Press Supplementary Mutagenicity Tests

    15 in stock

    a huge range and FREE tracked UK delivery on ALL orders.

    15 in stock

    £24.99

  • Biomarkers in Toxicology

    Elsevier Science Publishing Co Inc Biomarkers in Toxicology

    15 in stock

    Book SynopsisTable of ContentsPart I. Toxicity Testing Models and Biomarkers1. Introduction2. Rodent Models for Toxicity Testing and Biomarkers3. The Göttingen Minipig as large animal model in toxicology4. Nonhuman primates in preclinical research5. Biomarkers of toxicity in zebrafish6. Mechanistic Toxicology Biomarkers in Caenorhabditis elegans7. Drosophila melanogaster, Eisenia fetida, and Daphnia magna for toxicity testing and Biomarkers 8. Alternative animal toxicity testing and biomarkers9. Adverse outcome pathways and biomarkers Part II. Systems Toxicity Biomarkers10. Central nervous system toxicity biomarkers11. Peripheral nervous system toxicity biomarkers12. Cardiovascular toxicity biomarkers13. Respiratory toxicity biomarkers14. Hepatic toxicity biomarkers15. Conventional and emerging renal biomarkers16. Gastrointestinal toxicity biomarkers17. Reproductive toxicity biomarkers18. Biomarkers of toxicity in human placenta19. Early Biomarkers of Acute and Chronic Pancreatitis20. Skeletal muscle toxicity biomarkers21. Ocular biomarkers in diseases and toxicities22. Biomarkers of Ototoxicity23. Blood and bone marrow toxicity biomarkers24. Immunotoxicity biomarkers Part III. Chemical Agents, Solvents and Gases Toxicity Biomarkers25. Bisphenol A (BPA) Biomarkers and Biomonitoring26. Insecticides27. Herbicides and fungicides28. Polychlorinated biphenyls, polybrominated biphenyls, and brominated flame retardants29. Polycyclic aromatic hydrocarbons30. Metals31. Melamine 32. Biomarkers of petroleum products toxicity 33. Biomarkers of chemical mixture toxicity34. Biomarkers of toxic solvents and gases Part IV. Biotoxins Biomarkers35. Freshwater cyanotoxins 36. Mycotoxins37. Poisonous plants: biomarkers for diagnosis Part V. Pharmaceuticals and Nutraceuticals Biomarkers38. Biomarkers of drug toxicity and safety evaluation 39. Risk Assessment, Regulation and the Role of Biomarkers for the Evaluation of Dietary Ingredients present in Dietary Supplements40. Nutriphenomics in rodent models: Impact of dietary choices on toxicological biomarkers Part VI. Nanomaterials and Radiation41. Engineered nanomaterials: Biomarkers of exposure and effect42. Biomarkers of Exposure and Responses to Ionizing Radiation Part VII. Carcinogens Biomonitoring and Cancer Biomarkers43. Biomonitoring exposures to carcinogens44. Genotoxicity biomarkers: Molecular basis of genetic variability and susceptibility45. Epigenetic biomarkers in toxicology46. Breast cancer biomarkers47. Pancreatic and ovarian cancer biomarkers48. Prostate cancer biomarkers Part VIII. Disease Biomarkers49. Biomarkers of Alzheimer’s disease50. Biomarkers of Parkinson’s disease51. Biomarkers for drugs of abuse and neuropsychiatric disorders: Models and mechanisms52. Osteoarthritis biomarkers53. Pathological biomarkers in toxicology54. Oral pathology biomarkers Part IX. Special Topics55. Biomarkers of mitochondrial dysfunction and toxicity 56. Biomarkers of blood-brain barrier dysfunction57. Biomarkers of oxidative/nitrosative stress and neurotoxicity58. Cytoskeletal disruption as a biomarker of developmental neurotoxicity59. Membrane transporters and transporter substrates as biomarkers for drug pharmacokinetics, pharmacodynamics, and toxicity/adverse events60. Citrulline: Pharmacological perspectives and role as a biomarker in diseases and toxicities Part X. Applications of Biomarkers in Toxicology61. Analysis of toxin- and toxicant-induced biomarker signatures using microarrays62. Biomarkers detection for toxicity testing using metabolomics63. Transcriptomic biomarkers in safety and risk assessment of chemicals64. Percellome toxicogenomics project as a source of biomarkers of chemical toxicity65. Proteomics in biomarkers of chemical toxicity66. Biomarkers for Testing Toxicity and Monitoring Exposure to Xenobiotics67. Biomarkers in epidemiology, risk assessment and regulatory toxicology

    15 in stock

    £215.00

  • Choked

    The University of Chicago Press Choked

    2 in stock

    Book Synopsis

    2 in stock

    £28.50

  • Most Delicious Poison

    Little Brown and Company Most Delicious Poison

    10 in stock

    Book Synopsis

    10 in stock

    £14.05

  • The Mold Survival Guide

    Johns Hopkins University Press The Mold Survival Guide

    Book SynopsisWith clear scientific explanations and expert advice, The Mold Survival Guide is a valuable resource for anyone worried about a common household problem that can have serious consequences.Trade ReviewWhat molds are, why and where they grow, and how to rid our living spaces of these dangerous fungal microorganisms. The authors furnish clear explanations, examples from actual situations, and valuable advice... A storehouse of knowledge presented in a readable style. Library Journal Mold is a hot issue today, but the problem dates back to biblical times. Jeffrey May, author of My House is Killing Me, is a recognized authority on indoor pollution who focuses here on mold-how it prospers, how it affects one's health, and how it can be remediated. Science News Their handbook delivers both scientific explanations and expert advice. The most common problems can be headed off or corrected once the homeowner understands the life cycle of mold. That alone is worth the price of the book. Boston Globe Magazine A good job on a subject most of us would find less than stimulating... Were I actively listing and selling homes, I would keep this book handy as a reference and I would take every opportunity to see how the issue is playing out at the local level. Home inspectors would obviously be a great source of information, both academic and practical. -- Dr. Kenneth W. Edwards Real Estate Professional 2004 The Mold Survival Guide details mold problems and eradication methods and includes photographs-some in color-that show what water damage and mold infestation look like. -- Jim Watkins Washington Times Mold. It's a scary, mystifying and shudder inducing word... The Mays explore what mold is, where and why it grows, how it flourishes, and how it may or may not cause health problems. Readers learn how to identify mold, how to prevent it from spreading and when to call an expert. Baltimore Sun Recommended particularly for concerned homeowners and renovation architects, The Mold Survival Guide: For Your Home and for Your Health outlines the causes of moisture problems in old and new buildings... Leading you through his most tried-and-true forensic methodologies, Jeff May gives you the tools to root out the causes of the bedeviling musty odors that have forced homeowners to flee their homes. -- Courtney Miller ArchitectureBoston This book will help you make sensible decisions and cut through the 'fear factor' language in a lot of advertising. -- Holly Hayes San Jose Mercury NewsTable of ContentsPrefaceAcknowledgementsPart I: The World of MoldChapter 1. The Indispensable Kingdom of FungiChapter 2. Watering Mold and Spreading SporesChapter 3. How Mold Affects Our HealthChapter 4. Mold Wages Battle: Then and NowPart II: The Search For MoldChapter 5. What Lurks BelowChapter 6. Mold in the MechanicalsChapter 7. The Spaces We Live InChapter 8. The Spaces We Don't Live InChapter 9. Testing for MoldPart III: The CleanupChapter 10. Small-Scale Cleanup JobsChapter 11. Professional RemediationConclusionResource GuideIndex

    £25.64

  • Stem Cells in Toxicology and Medicine

    John Wiley & Sons Inc Stem Cells in Toxicology and Medicine

    10 in stock

    Book SynopsisA comprehensive and authoritative compilation of up-to-date developments in stem cell research and its use in toxicology and medicine Presented by internationally recognized investigators in this exciting field of scientific researchProvides an insight into the current trends and future directions of research in this rapidly developing new fieldA valuable and excellent source of authoritative and up-to-date information for researchers, toxicologists, drug industry, risk assessors and regulators in academia, industry and governmentTable of ContentsList of Contributors xx Preface xxvi Acknowledgements xxvii PART I 1 1 Introduction 3 Saura C. Sahu References 4 2 Application of Stem Cells and iPS Cells in Toxicology 5 Maria Virginia Caballero, Ramon A. Espinoza‐Lewis, and Manila Candiracci 2.1 Introduction 5 2.2 Significance 6 2.3 Stem Cell (SC) Classification 7 2.4 Stem Cells and Pharmacotoxicological Screenings 8 2.5 Industrial Utilization Showcases Stem Cell Technology as a Research Tool 8 2.6 Multipotent Stem Cells (Adult Stem Cells) Characteristics and Current Uses 9 2.7 Mesenchymal Stem Cells (Adult Stem Cells) 10 2.8 Hematopoietic Stem Cells (Adult Stem Cells) 11 2.9 Cardiotoxicity 12 2.10 Hepatotoxicity 15 2.11 Epigenetic Profile 17 2.12 Use of SC and iPSC in Drug Safety 18 2.13 Conclusions and Future Applications 19 Acknowledgments 19 References 19 3 Stem Cells: A Potential Source for High Throughput Screening in Toxicology 26 Harish K Handral, Gopu Sriram, and Tong Cao 3.1 Introduction 26 3.2 Stem Cells 27 3.3 High Throughput Screening (HTS) 31 3.4 Need for a Stem Cell Approach in High Throughput Toxicity Studies 37 3.5 Role of Stem Cells in High Throughput Screening for Toxicity Prediction 38 3.6 Conclusion 40 Acknowledgement 41 Disclosure Statement 41 Author’s Contribution 41 References 41 4 Human Pluripotent Stem Cells for Toxicological Screening 50 Lili Du and Dunjin Chen 4.1 Introduction 50 4.2 The Biological Characteristics of hPSCs 51 4.3 Screening of Embryotoxic Effects using hPSCs 52 4.4 The Potential of hPSC‐Derived Neural Lineages in Neurotoxicology 55 4.5 The Potential of hPSC ‐Derived Cardiomyocytes in Cardiotoxicity 60 4.6 The Potential of hPSC‐Derived Hepatocytes in Hepatotoxicity 62 4.7 Future Challenges and Perspectives for Embryotoxicity and Developmental Toxicity Studies using hPSCs 65 Acknowledgments 66 References 67 5 Effects of Culture Conditions on Maturation of Stem Cell‐Derived Cardiomyocytes 71 Deborah K. Hansen, Amy L. Inselman, and Xi Yang 5.1 Introduction 71 5.2 Lengthening Culture Time 75 5.3 Substrate Stiffness 76 5.4 Structured Substrates 78 5.5 Conclusions 82 Disclaimer 82 References 83 6 Human Stem Cell‐Derived Cardiomyocyte In Vitro Models for Cardiotoxicity Screening 85 Tracy Walker, Kate Harris, Evie Maifoshie, and Khuram Chaudhary 6.1 Introduction 85 6.2 Overview of hPSC‐Derived Cardiomyocytes 88 6.3 Human PSC‐CM Models for Cardiotoxicity Investigations 90 6.4 Conclusions and Future Direction 112 References 112 7 Disease‐Specific Stem Cell Models for Toxicological Screenings and Drug Development 122 Matthias Jung, Juliane‐Susanne Jung, Jovita Schiller, and Insa S. Schroeder 7.1 Evidence for Stem Cell‐Based Drug Development and Toxicological Screenings in Psychiatric Diseases, Cardiovascular Diseases and Diabetes 122 7.2 Disease‐Specific Stem Cell Models for Drug Development in Psychiatric Disorders 127 7.3 Stem Cell Models for Cardiotoxicity and Cardiovascular Disorders 132 7.4 Stem Cell Models for Toxicological Screenings of EDCs 133 References 135 8 Three‐Dimensional Culture Systems and Humanized Liver Models Using Hepatic Stem Cells for Enhanced Toxicity Assessment 145 Ran‐Ran Zhang, Yun‐Wen Zheng, and Hideki Taniguchi 8.1 Introduction 145 8.2 Hepatic Cell Lines and Primary Human Hepatocytes 146 8.3 Embryonic Stem Cells and Induced Pluripotent Stem‐Cell Derived Hepatocytes 147 8.4 Ex Vivo: Three‐Dimensional and Multiple‐Cell Culture System 148 8.5 In Vivo: Humanized Liver Models 149 8.6 Summary 150 Acknowledgments 150 References 150 9 Utilization of In Vitro Neurotoxicity Models in Pre‐Clinical Toxicity Assessment 155 Karin Staflin, Dinah Misner, and Donna Dambach 9.1 Introduction 155 9.2 Current Models of Drug‐Related Clinical Neuropathies and Effects on Electrophysiological Function 159 9.3 Cell Types that Can Potentially Be Used for In Vitro Neurotoxicity Assessment in Drug Development 162 9.4 Utility of iPSC Derived Neurons in In Vitro Safety Assessment 167 9.5 Summary of Key Points for Consideration in Neurotoxicity Assay Development 170 9.6 Concluding Remarks 172 References 172 10 A Human Stem Cell Model for Creating Placental Syncytiotrophoblast, the Major Cellular Barrier that Limits Fetal Exposure to Xenobiotics 179 R. Michael Roberts, Shinichiro Yabe, Ying Yang, and Toshihiko Ezashi 10.1 Introduction 179 10.2 General Features of Placental Structure 180 10.3 The Human Placenta 180 10.4 Human Placental Cells in Toxicology Research 182 10.5 Placental Trophoblast Derived from hESC 183 10.6 Isolation of Syncytial Areas from BAP‐Treated H1 ESC Colonies 185 10.7 Developmental Regulation of Genes Encoding Proteins Potentially Involved in Metabolism of Xenobiotics 185 10.8 Concluding Remarks 191 Acknowledgments 192 References 192 11 The Effects of Endocrine Disruptors on Mesenchymal Stem Cells 196 Marjorie E. Bateman, Amy L. Strong, John McLachlan, Matthew E. Burow, and Bruce A. Bunnell 11.1 Mesenchymal Stem Cells 196 11.2 Endocrine Disruptors 198 11.3 Pesticides 201 11.4 Alkyl Phenols and Derivatives 206 11.5 Bisphenol A 211 11.6 Polychlorinated Biphenyls 216 11.7 Phthalates 221 11.8 Areas for Future Research 225 11.9 Conclusions 226 Abbreviations 226 References 228 12 Epigenetic Landscape in Embryonic Stem Cells 238 Xiaonan Sun, Nicholas Spellmon, Joshua Holcomb, Wen Xue, Chunying Li, and Zhe Yang 12.1 Introduction 238 12.2 DNA Methylation in ESCs 239 12.3 Histone Methylation in ESCs 240 12.4 Chromatin Remodeling and ESCs Regulation 241 12.5 Concluding Remarks 242 Acknowledgements 243 References 243 PART II 247 13 The Effect of Human Pluripotent Stem Cell Platforms on Preclinical Drug Development 249 Kevin G. Chen 13.1 Introduction 249 13.2 Core Signaling Pathways Underlying hPSC Stemness and Differentiation 250 13.3 Basic Components of In Vitro and Ex Vivo hPSC Platforms 251 13.4 Diverse hPSC Culture Platforms for Drug Discovery 252 13.5 Representative Analyses of hPSC‐Based Drug Discovery 255 13.6 Current Challenges and Future Considerations 257 13.7 Concluding Remarks 260 Acknowledgments 260 References 260 14 Generation and Application of 3D Culture Systems in Human Drug Discovery and Medicine 265 H. Rashidi and D.C. Hay 14.1 Introduction 265 14.2 Traditional Scaffold‐Based Tissue Engineering 266 14.3 Scaffold‐Free 3D Culture Systems 269 14.4 Modular Biofabrication 270 14.5 3D Bioprinting 270 14.6 Tissue Modelling and Regenerative Medicine Applications of Pluripotent Stem Cells 272 14.7 Applications in Drug Discovery and Toxicity 275 14.8 Conclusions 278 References 278 15 Characterization and Therapeutic Uses of Adult Mesenchymal Stem Cells 288 Juliann G. Kiang 15.1 Introduction 288 15.2 MSC Characterization 289 15.3 MSCs and Tissue or Organ Therapy 293 15.4 Conclusions 298 Acknowledgments 298 References 298 16 Stem Cell Therapeutics for Cardiovascular Diseases 303 Yuning Hou, Xiaoqing Guan, Shukkur M. Farooq, Xiaonan Sun, Peijun Wang, Zhe Yang, and Chunying Li 16.1 Introduction 303 16.2 Types of Stem/Progenitor Cell‐Derived Endothelial Cells 304 16.3 EPC and Other Stem/Progenitor Cell Therapy in CVDs 306 16.4 Strategies and Approaches for Enhancing EPC Therapy in CVDs 306 16.5 Concluding Remarks 315 Acknowledgments 316 References 316 17 Stem‐Cell‐Based Therapies for Vascular Regeneration in Peripheral Artery Diseases 324 David M Smadja and Jean‐Sébastien Silvestre 17.1 Sources of Stem Cells for Vascular Regeneration 325 17.2 Canonic Mechanisms Governing Vascular Stem Cells Therapeutic Potential 329 17.3 Stem‐Cell‐Based Therapies in Patients with Peripheral Artery Disease 333 References 337 18 Gene Modified Stem/Progenitor‐Cell Therapy for Ischemic Stroke 347 Yaning Li, Guo‐Yuan Yang, and Yongting Wang 18.1 Introduction 347 18.2 Gene Modified Stem Cells for Ischemic Stroke 348 18.3 Gene Transfer Vectors 354 18.4 Unsolved Issues for Gene‐Modified Stem Cells in Ischemic Stroke 356 18.5 Conclusion 356 Abbreviations 356 Acknowledgments 357 References 357 19 Role of Stem Cells in the Gastrointestinal Tract and in the Development of Cancer 363 Pengyu Huang, Bin Li, and Yun‐Wen Zheng 19.1 Introduction 363 19.2 GI Development and Regeneration 365 19.3 GI Tumorigenesis and Stemness Gene Expression 367 19.4 Toxicants and Other Stress Trigger Epigenetic Changes, Dedifferentiation, and Carcinogenesis 368 19.5 Summary and Perspective 369 Acknowledgments 369 References 370 20 Cancer Stem Cells: Concept, Significance, and Management 375 Haseeb Zubair, Shafquat Azim, Sanjeev K. Srivastava, Arun Bhardwaj, Saravanakumar Marimuthu, Mary C. Patton, Seema Singh, and Ajay P. Singh 20.1 Introduction 375 20.2 Stem Cells and Cancer: Historical Perspective 376 20.3 Cancer Stem Cells 377 20.4 Identification and Isolation of CSCs 382 20.5 Pathological Significance of Cancer Stem Cells 388 20.6 Pathways Regulating Cancer Stem Cells 389 20.7 Therapeutic Strategies Targeting Cancer Stem Cells 394 20.8 Conclusion and Future Directions 399 References 400 21 Stem Cell Signaling in the Heterogeneous Development of Medulloblastoma 414 Joanna Triscott and Sandra E. Dunn 21.1 Brain Tumor Cancer Stem Cells 414 21.2 Medulloblastoma 416 21.3 Hijacking Cerebellar Development 417 21.4 Molecular Classification of MB 420 21.5 Mouse Models and Cell of Origin 424 21.6 Additional Drivers of MB 425 21.7 Repurposing Off‐Patent Drugs 426 21.8 Emerging Therapies for MB 428 21.9 Conclusion 429 Acknowledgments 429 References 429 22 Induced Pluripotent Stem Cell‐Derived Outer-Blood‐Retinal Barrier for Disease Modeling and Drug Discovery 436 Jun Jeon, Nathan Hotaling, and Kapil Bharti 22.1 Introduction 436 22.2 The Outer Blood‐Retinal Barrier 437 22.3 iPSC‐Based Model of the Outer-Blood‐Retinal-Barrier 439 22.4 iPSC Based OBRB Disease Models 442 22.5 Applications of iPSC‐Based Ocular Disease Models for Drug Discovery 448 22.6 Conclusion and Future Directions 451 References 451 23 Important Considerations in the Therapeutic Application of Stem Cells in Bone Healing and Regeneration 458 Hoda Elkhenany, Shawn Bourdo, Alexandru Biris, David Anderson, and Madhu Dhar 23.1 Introduction 458 23.2 Stem Cells, Progenitor Cells, Mesenchymal Stem Cells 459 23.3 Scaffolds 461 23.4 Animal Models in Bone Healing and Regeneration 464 23.5 Conclusions and Future Directions 472 References 472 24 Stem Cells from Human Dental Tissue for Regenerative Medicine 481 Junjun Liu and Shangfeng Liu 24.1 Introduction 481 24.2 Dental Stem Cells 482 24.3 Potential Clinical Applications 488 24.4 Safety 492 24.5 Dental Stem Cell Banking 493 24.6 Conclusions and Perspective 494 References 495 25 Stem Cells in the Skin 502 Hongwei Wang, Zhonglan Su, Shiyu Song, Ting Su, Mengyuan Niu, Yaqi Sun, and Hui Xu 25.1 Introduction 502 25.2 Stem Cells in the Skin 503 25.3 Isolation and the Biological Markers of Skin Stem Cells 506 25.4 Skin Stem Cell Niches 508 25.5 Signaling Control of Stem Cell Differentiation 510 25.6 Stem Cells in Skin Aging 514 25.7 Stem Cells in Skin Cancer 516 25.8 Medical Applications of Skin Stem Cells 518 25.9 Conclusions and Future Directions 520 References 521 Author Index 527 Subject Index 529

    10 in stock

    £151.95

  • Strategic Allocation and Management of Capital in

    Health Administration Press Strategic Allocation and Management of Capital in

    Book Synopsis

    £63.00

  • Slow Death by Rubber Duck: The Secret Danger of

    Counterpoint Slow Death by Rubber Duck: The Secret Danger of

    10 in stock

    Book SynopsisA look at the chemicals surrounding us that’s “hard-hitting . . . yet also instills hope for a future in which consumers make safer, more informed choices” (The Washington Post). Pollution is no longer just about belching smokestacks and ugly sewer pipes—now, it’s personal.The most dangerous pollution, it turns out, comes from commonplace items in our homes and workplaces. To prove this point, for one week Rick Smith and Bruce Lourie ingested and inhaled a host of things that surround all of us. Using their own bodies as the reference point to tell the story of pollution in our modern world, they expose the corporate giants who manufacture the toxins, the government officials who let it happen, and the effects on people and families across the globe.This book—the testimony of their experience—also exposes the extent to which we are poisoned every day of our lives, from the simple household dust that is polluting our blood to the toxins in our urine that are created by run-of-the-mill shampoos and toothpaste. Ultimately hopeful, the book empowers readers with some simple ideas for protecting themselves and their families, and changing things for the better. “Undertaking a cheeky experiment in self-contamination, professional Canadian environmentalists Smith and Lourie expose themselves to hazardous everyday substances, then measure the consequences . . . Throughout, the duo weave scientific data and recent political history into an amusing but unnerving narrative, refusing to sugarcoat any of the data while maintaining a welcome sense of humor.” —Publishers Weekly (starred review)

    10 in stock

    £13.98

  • Venom: The Secrets of Nature's Deadliest Weapon

    Smithsonian Books Venom: The Secrets of Nature's Deadliest Weapon

    10 in stock

    Book SynopsisVenom brings readers face to face with some of the most dangerous creatures on the planet, including jellyfish, snakes, and wasps, as it uncovers the story of venom. The book explores how venom is used for predation, defense, competition, and communication by an incredible diversity of species. It examines the unique methods that these species have evolved to create and deliver their deadly toxins. The book traces venom back to its origin in early jellyfish and sea anemones, and reveals how venoms have evolved dozens of times independently all across the animal kingdom since that time. And finally, it examines the relationships between these dangerous creatures and humans. Humans have not only learned to live with them, but also to benefit from them: scientists increasingly are harnessing the power of venom to create new drugs, treatments, and anti-venoms.

    10 in stock

    £17.95

  • World Health Organization Evaluation of Certain Veterinary Drug Residues in

    5 in stock

    Book Synopsis

    5 in stock

    £32.47

  • Evaluation of Certain Food Additives:

    World Health Organization Evaluation of Certain Food Additives:

    1 in stock

    Book Synopsis

    1 in stock

    £42.38

  • Shiga toxinproducing Escherichia coli STEC and

    World Health Organization Shiga toxinproducing Escherichia coli STEC and

    15 in stock

    Book Synopsis

    15 in stock

    £45.60

  • Strontium and Strontium Compounds

    World Health Organization Strontium and Strontium Compounds

    3 in stock

    Book Synopsis

    3 in stock

    £23.17

  • Foodborne Disease Outbreaks: Guidelines for

    World Health Organization Foodborne Disease Outbreaks: Guidelines for

    4 in stock

    Book Synopsis

    4 in stock

    £28.61

  • Uncertainty and Data Quality in Exposure

    World Health Organization Uncertainty and Data Quality in Exposure

    3 in stock

    Book Synopsis

    3 in stock

    £42.68

  • DDT in Indoor Residual Spraying: Human Health

    World Health Organization DDT in Indoor Residual Spraying: Human Health

    3 in stock

    Book Synopsis

    3 in stock

    £61.30

  • A Guide on Safe Food for Travellers How to Avoid

    World Health Organization A Guide on Safe Food for Travellers How to Avoid

    7 in stock

    Book Synopsis

    7 in stock

    £22.80

  • Safety Evaluation of Certain Food Additives:

    World Health Organization Safety Evaluation of Certain Food Additives:

    1 in stock

    Book Synopsis

    1 in stock

    £90.52

  • Safety Evaluation of Certain Food Additives:

    World Health Organization Safety Evaluation of Certain Food Additives:

    4 in stock

    Book Synopsis

    4 in stock

    £148.65

  • Safety Evaluation of Certain Food Additives:

    World Health Organization Safety Evaluation of Certain Food Additives:

    3 in stock

    Book Synopsis

    3 in stock

    £43.67

  • Some Non-Heterocyclic Polycyclic Aromatic

    International Agency for Research on Cancer Some Non-Heterocyclic Polycyclic Aromatic

    2 in stock

    Book Synopsis

    2 in stock

    £57.00

  • International Agency for Research on Cancer Control de Las Micotoxinas En Los Países de

    2 in stock

    Book Synopsis

    2 in stock

    £22.80

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