Inorganic chemistry Books
Cambridge University Press New Pathways in Inorganic Chemistry
a huge range and FREE tracked UK delivery on ALL orders.
£45.59
Cambridge University Press Inorganic Energetics
a huge range and FREE tracked UK delivery on ALL orders.
£50.95
Cambridge University Press Liquid Metals
a huge range and FREE tracked UK delivery on ALL orders.
£158.65
Cambridge University Press Inorganic Substances
a huge range and FREE tracked UK delivery on ALL orders.
£48.44
Cambridge University Press Proton Conductors Solids Membranes and Gels Materials and Devices 2 Chemistry of Solid State Materials Series Number 2
a huge range and FREE tracked UK delivery on ALL orders.
£176.40
Cambridge University Press The Fullerenes
a huge range and FREE tracked UK delivery on ALL orders.
£40.84
Cambridge University Press Liquid Crystals Experimental Study of Physical Properties and Phase Transitions
a huge range and FREE tracked UK delivery on ALL orders.
£127.00
Cambridge University Press Handbook of Isotopes in the Cosmos
a huge range and FREE tracked UK delivery on ALL orders.
£73.14
Cambridge University Press Electronic Basis of the Strength of Materials
a huge range and FREE tracked UK delivery on ALL orders.
£112.22
Cambridge University Press Supramolecular Organization and Materials Design
a huge range and FREE tracked UK delivery on ALL orders.
£114.95
Cambridge University Press Structure and Bonding in Crystalline Materials
a huge range and FREE tracked UK delivery on ALL orders.
£83.59
Cambridge University Press Valency and Bonding
a huge range and FREE tracked UK delivery on ALL orders.
£160.55
Cambridge University Press Molecular Clusters A Bridge to SolidState Chemistry Cambridge Molecular Science
a huge range and FREE tracked UK delivery on ALL orders.
£125.48
John Wiley & Sons Inc Fragments of Fullerenes and Carbon Nanotubes
Book SynopsisThis book is the first of its kindto reflect upon theintense and rapidly growing interest in open geodesic polyaromatic molecules, specifically focusing on their synthesis and reactivity in metal binding reactions. The book broadly covers all aspects related to the fullerene fragment chemistry: current synthetic techniques, description of the available members of this new family (which has grown tomore thantwo dozens members, with none being available commercially), molecular geometry and trends in the solid state packing, as well as extensions into physical properties and new buckybowl-based molecules and materials. It covers fundamental research related to a new class of hydrocarbons, namely open geodesic polyarenes that map onto the surfaces of fullerenes (and referred to as fullerene fragments or buckybowls.Trade Review“Despite the many exciting papers published since this book became available in 2012, this monograph will be a valuable addition to any library, an enjoyable page turner for aficionados of hydrocarbon chemistry, and a treasure trove for advanced students of organic chemistry.” (Chemistry International, 1 May 2013)Table of ContentsPREFACE vii FOREWORD xi CONTRIBUTORS xiii ACRONYMS xvii 1 MOLECULAR CLIPS AND TWEEZERS WITH CORANNULENE PINCERS 1 Andrzej Sygula and Willard E. Collier 2 SYNTHESIS OF BOWL-SHAPED AND BASKET-SHAPED FULLERENE FRAGMENTS VIA BENZANNULATED ENYNE---ALLENES 41 Kung K. Wang, Hu Cui, and Bo Wen 3 ANIONS OF BUCKYBOWLS 63 David Eisenberg, Roy Shenhar, and Mordecai Rabinovitz 4 CURVED p-CONJUGATED STABLE OPEN-SHELL SYSTEMS POSSESSING THREE-DIMENSIONAL MOLECULAR/ELECTRONIC SPIN STRUCTURES 95 Yasushi Morita and Akira Ueda 5 EXPERIMENTAL AND CALCULATED PROPERTIES OF FULLERENE AND NANOTUBE FRAGMENTS 135 Derek R. Jones, Praveen Bachawala, and James Mack 6 COORDINATION PREFERENCES OF BOWL-SHAPED POLYAROMATIC HYDROCARBONS 157 Alexander S. Filatov and Marina A. Petrukhina 7 SUMANENES: SYNTHESIS AND COMPLEXATION 187 Toshikazu Hirao and Toru Amaya 8 r-BONDED TRANSITION METAL COMPLEXES OF POLYCYCLIC AROMATIC CARBON COMPOUNDS 205 Paul R. Sharp 9 HEMISPHERICAL GEODESIC POLYARENES: ATTRACTIVE TEMPLATES FOR THE CHEMICAL SYNTHESIS OF UNIFORM-DIAMETER ARMCHAIR NANOTUBES 235 Anthony P. Belanger, Katharine A. Mirica, James Mack, and Lawrence T. Scott 10 AROMATIC BELTS AS SECTIONS OF NANOTUBES 259 Gaston R. Schaller and Rainer Herges 11 CYCLOPARAPHENYLENES: THE SHORTEST POSSIBLE SEGMENTS OF ARMCHAIR CARBON NANOTUBES 291 Xia Tian and Ramesh Jasti 12 CONJUGATED MOLECULAR BELTS BASED ON 3D BENZANNULENE SYSTEMS 311 Masahiko Iyoda, Yoshiyuki Kuwatani, Tohru Nishinaga, Masayoshi Takase, and Tomohiko Nishiuchi 13 TOWARD FULLY UNSATURATED DOUBLE-STRANDED CYCLES 343 Malte Standera and A. Dieter Schl€uter 14 BENT PYRENES: SPRINGBOARDS TO AROMATIC BELTS? 367 Graham J. Bodwell, Gandikota Venkataramana, and Unikela Kiran Sagar INDEX 401
£124.40
John Wiley & Sons Inc Dithiolene Chemistry Synthesis Properties and
Book SynopsisA selection of papers providing critical evaluations of advances made in dithiolene chemistry. This work covers dithiolene complexes and their noteworthy properties.Trade Review"…a valuable contribution to the literature…the editor should be congratulated upon producing it to such a high standard. I recommend it unreservedly…" (Angewandte Chemie, December 17, 2004) "…a balanced and comprehensive treatment of incontestable currency and utility…a primary, and possibly indispensable, resource." (Journal of the American Chemical Society, August 11, 2004) “…an extremely useful addition…” (Applied Organometallic Chemistry, Vol 18, No 8, August 2004)Table of ContentsChapter 1: Synthesis of Transition Metal Dithiolenes (T. B. Rauchfuss). Chapter 2: Structures and Structural Trends in Homoleptic Dithiolene Complexes (C. L. Beswick, J. M. Schulman, and E. I. Stiefel). Chapter 3: The Electronic Structure and Spectroscopy of Metallo-Dithiolene Complexes (M. L. Kirk, R. L. McNaughton, and M. E. Helton). Chapter 4: Vibrational Spectra of Dithiolene Complexes (M. K. Johnson). Chapter 5: Electrochemical and Chemical Reactivity of Dithiolene Complexes (K. Wang). Chapter 6: Luminescence and Photochemistry of Metal Dithiolene Complexes (S. D. Cummings and R. Eisenberg). Chapter 7: Metal Dithiolene Complexes in Detection: Past, Present, and Future (K. A. Van Houten and R. S. Pilato). Chapter 8: Solid-State Properties (Electronic, Magnetic, Optical) of Dithiolene Complex-Based Compunds (C. Faulmann and P. Cassoux). Chapter 9: Dithiolenes in Biology (S. J. N. Burgmayer). Chapter 10: Chemical Analogues of the Catalytic Centers of Molybdenum and Tungsten Ditholene-Containing Enzymes (J. McMaster, J. M. Tunney, and C. D. Garner). Chapter 11: Dithiolenes in More Complex Ligands (D. Sellmann and J. Sutter). Subject Index. Cumulative Index, Volumes 1–52.
£244.10
John Wiley & Sons Inc Progress in Inorganic Chemistry 54
Book SynopsisThe cutting edge of scientific reporting... PROGRESS in Inorganic Chemistry Nowhere is creative scientific talent busier than in the world of inorganic chemistry experimentation. Progress in Inorganic Chemistry continues in its tradition of being the most respected avenue for exchanging innovative research.Trade Review"...makes one realize that the discipline of inorganic chemistry is remarkably broad and new fields are continually being created...an important and valuable addition to the series." (Journal of the American Chemical Society, September 28, 2005)Table of ContentsChapter 1: Atomlike Building Units of Adjustable Character: Solid-State and Solution Routes to Manipulating Hexanuclear Transition Metal Chalcohalide Clusters (Eric J. Welch and Jeffrey R. Long). Chapter 2: Doped Semiconductor Nanocrystals: Synthesis, Characterization, Physical Properties, and Applications (J. Daniel Bryan and Daniel R. Gamelin). Chapter 3: Stereochemical Aspects of Metal Xanthate Complexes: Molecular Structures and Supramolecular Self-Assembly (Edward R. T. Tiekink and Ionel Haiduc). Chapter 4: Trivalent Uranium: A Versatile Species for Molecular Activation (Ilia Korobkov and Sandro Gambarotta). Chapter 5: Comparison of the Chemical Biology of NO and HNO: An Inorganic Perspective (Katrina M. Miranda, Lisa Ridnour, Michael Esprey, Deborah Citrin, Douglas Thomas, Daniele Mancardi, Sonia Donzelli, David A. Wink, Tatsuo Katori, Carlo G. Tocchetti, Marcella Ferlito, Nazareno Paolocci and Jon M. Fukuto). Chapter 6: Alterations of Nucleobase pKa Values upon Metal Coordination: Origins and Consequences (Bernhard Lippert). Chapter 7: Functionalization of Myoglobin (Yoshihito Watanabe and Takashi Hayashi). Subject Index. Cumulative Index, Volumes 1–54.
£221.30
John Wiley & Sons Inc The Lightest Metals
Book SynopsisThe first seven metals in the periodic table are lithium, beryllium, sodium, magnesium, aluminium, potassium and calcium, known collectively as the lightest metals. The growing uses of these seven elements are enmeshing them ever more firmly into critical areas of 21st century technology, including energy storage, catalysis, and various applications of nanoscience. This volume provides comprehensive coverage of the fundamentals and recent advances in the science and technology of the lightest metals. Opening chapters of the book describe major physical and chemical properties of the metals, their occurrence and issues of long-term availability. The book goes on todisucss a broad range of chemical features, including low oxidation state chemistry, organometallics, metal-centered NMR spectroscopy, and cation-p interactions. Current and emerging applications of the metals are presented, including lithium-ion battery technology, hydrogen storage chemistry, superconductor materiTable of ContentsContributors XI Series Preface XV Volume Preface XVII PART 1: BACKGROUND 1 Interrelationships between the Lightest Metals 3Nicholas C. Boyde and Timothy P. Hanusa Occurrence and Production of Beryllium 23Stephen Freeman Occurrence of Magnesia Minerals and Production of Magnesium Chemicals and Metal 35Mark A. Shand Occurrence and Production of Aluminum 47Halvor Kvande Status as Strategic Metals 57Deborah A. Kramer Resource Sustainability 67David A. Atwood PART 2: FUNDAMENTALS 71 Low Oxidation State Chemistry 73Michael S. Hill Solution NMR of the Light Main Group Metals 91Timothy P. Hanusa Solid-State NMR of the Light Main Group Metals 117Robert W. Schurko and Michael J. Jaroszewicz Cation–π Interactions 173Yi An and Steven E. Wheeler Ion Channels and Ionophores 185Peter J. Cragg Beryllium Metal Toxicology: A Current Perspective 205Terence M. Civic PART 3: APPLICATIONS 211 Reimagining the Grignard Reaction 213Sven Krieck and Matthias Westerhausen Aryllithiums and Hetaryllithiums: Generation and Reactivity 231D. W. Slocum Magnesium and Calcium Complexes in Homogeneous Catalysis 255Merle Arrowsmith Aluminum-Based Catalysis 281Mark R. Mason Lithium-Ion Batteries: Fundamentals and Safety 303Isidor Buchmann Li-Ion Batteries and Beyond: Future Design Challenges 315Yoon Hwa and Elton J. Cairns High-Pressure Synthesis of Hydrogen Storage Materials 335Hiroyuki Saitoh, Shigeyuki Takagi, Katsutoshi Aoki and Shin-ichi Orimo Processing and Applications of Transparent Ceramics 343Ling Bing Kong, Yizhong Huang, Zhili Dong, Tianshu Zhang, Wenxiu Que, Jian Zhang, Dingyuan Tang and Sean Li Light-Element Superconductors 371Andreas Hermann One-dimensional Nanostructure-enhanced Catalysis 387Sibo Wang, Zheng Ren, Yanbing Guo and Pu-Xian Gao Lithium Pharmacology 417Philip G. Janicak and Bradley R. Cutler Solar Energy and Photovoltaics 427Arnulf Jäger-Waldau Abbreviations and Acronyms 437 Index 441
£138.22
John Wiley & Sons Inc Essentials of Inorganic Materials Synthesis
Book SynopsisThis compact handbook describes all the important methods of synthesis employed today for synthesizing inorganic materials.Table of ContentsAuthor Biographies vii Preface ix 1 Introduction 1 2 Common Reactions Employed in Synthesis 7 2.1 Soft-Chemistry Routes, 12 3 Ceramic Methods 17 4 Decomposition of Precursor Compounds 23 5 Combustion Synthesis 33 6 Arc and Skull Methods 37 7 Reactions at High Pressures 41 8 Mechanochemical and Sonochemical Methods 47 8.1 Mechanochemistry, 47 8.2 Sonochemistry, 50 9 Use of Microwaves 53 10 Soft Chemistry Routes 57 10.1 Topochemical Reactions, 57 10.2 Intercalation Chemistry, 64 10.3 Ion Exchange Reactions, 73 10.4 Use of Fluxes, 78 10.5 Sol–Gel Synthesis, 81 10.6 Electrochemical Methods, 86 10.7 Hydrothermal, Solvothermal and Ionothermal Synthesis, 90 11 Nebulized Spray Pyrolysis 97 12 Chemical Vapour Deposition and Atomic Layer Deposition 103 13 Nanomaterials 107 13.1 Nanoparticles, 107 13.2 Core–Shell Nanocrystals, 116 13.3 Nanowires, 119 13.4 Inorganic Nanotubes, 133 13.5 Graphene-like Structures of Layered Inorganic Materials, 137 14 Materials 151 14.1 Metal Borides, Carbides and Nitrides, 151 14.2 Metal Chalcogenides, 157 14.3 Metal Halides, 162 14.4 Metal Silicides and Phosphides, 167 14.5 Intergrowth Structures and Misfit Compounds, 171 14.5.1 Intergrowth structures, 171 14.5.2 Misfit Compounds, 177 14.6 Intermetallic Compounds, 178 14.7 Superconducting Compounds, 182 14.8 Porous Materials, 191 14.8.1 Mesoporous Silica Materials, 191 14.8.2 Aluminophosphates, 194 14.8.3 Metal Organic Frameworks (MOFs), 196 Index 201
£82.60
John Wiley and Sons Ltd Toxicology of Cyanides and Cyanogens
Book SynopsisThe basic and applied toxicology of cyanides and cyanogens has widespread commercial, occupational, environmental, clinical, forensic, military, and public health implications. This book provides a detailed and updated reference describing the properties, uses, general and human toxicology, clinical recognition, diagnosis and medical management, and countermeasures is therefore required in academic, medical, occupational, environmental, medico-legal, regulatory, emergency response, and military arenas. Edited by a world-renowned team of experts from academia, defense and industry, this book will be an invaluable reference for professionals, researchers and students in cyanide and cyanogens.Table of ContentsList of Contributors xv Foreword xix 1 Acute cyanide toxicity 1Andrea R. Allen, Lamont Booker, and Gary A. Rockwood 1.1 Introduction 1 1.2 Pharmacokinetic properties of cyanide 2 1.3 Pharmacodynamic properties of cyanide 4 1.4 Acute cyanide toxicity – routes of administration 5 1.5 Neurological and behavioral effects following acute cyanide exposure 12 1.6 Summary 14 References 14 2 Chronic cyanide exposure 21Jason D. Downey, Kelly A. Basi, Margaret R. DeFreytas, and Gary A. Rockwood 2.1 Introduction 21 2.2 Sources of chronic cyanide exposure 21 2.3 Chronic cyanide exposure in human disease 23 2.4 Experimental models of chronic cyanide exposure 30 2.5 Conclusion 35 References 36 3 Physicochemical properties synthesis applications and transport 41David E. Thompson and Ilona Petrikovics 3.1 Introduction 41 3.2 Natural sources of cyanide 41 3.3 Isolation and characterization of cyanide 43 3.4 Industrial production of cyanide 44 3.5 Applications and uses of cyanide 46 Acknowledgments 50 References 50 4 Cyanide metabolism and physiological disposition 54Gary E. Isom, Joseph L. Borowitz, and Alan H. Hall 4.1 Introduction 54 4.2 Metabolism and toxicokinetics 55 4.3 Non-enzymatic detoxification of cyanide 63 4.4 Diseases associated with altered cyanide metabolism 64 4.5 Metabolism and endogenous generation of cyanide 65 References 65 5 Biochemical mechanisms of cyanide toxicity 70Gary E. Isom and Joseph L. Borowitz 5.1 Introduction 70 5.2 Cytochrome oxidase inhibition and mitochondrial dysfunction 72 5.3 Oxidative stress and inhibition of cellular oxidative defense 75 5.4 Cyanide-induced changes in cellular Ca2+ regulation 76 5.5 Cyanide-induced cell death and post-intoxication lesions 77 5.6 Alteration of intermediary metabolism and lactic acidosis 78 5.7 Conclusion 78 References 79 6 Environmental toxicology of cyanide 82Samantha L. Malone, Linda L. Pearce, and Jim Peterson 6.1 Introduction 82 6.2 Environmentally relevant chemistry of cyanides 83 6.3 Occupational concerns 87 6.4 Ground/surface water 87 6.5 Exposure to cyanogens through diet 89 6.6 Dietary health hazards 89 6.7 Cassava consumption 90 6.8 Fires and smoke 91 6.9 Conclusion 92 References 93 7 Cyanide in the production of long-term adverse health effects in humans 98Julie Cliff, Hipolito Nzwalo, and Humberto Muquingue 7.1 Introduction 98 7.2 Long-term adverse health effects 100 7.3 Conclusions 107 References 107 8 Pediatric cyanide poisoning 113Robert J. Geller 8.1 Introduction 113 8.2 Sources of acute cyanide poisoning in children 114 8.3 Manifestations of acute cyanide poisoning 122 8.4 Cyanide antidotes 124 8.5 Conclusion 126 References 126 9 Sodium nitroprusside in intensive care medicine and issues of cyanide poisoning cyanide poisoning prophylaxis and thiocyanate poisoning 129Prasad Abraham, Alissa Lockwood, John Patka, Marina Rabinovich, Jennifer Sutherland, and Katleen Chester 9.1 Introduction 129 9.2 History 129 9.3 Mechanism of action 130 9.4 Metabolism 1309.5 Evidence for CN− toxicity associated with SNP 1329.6 Incidence of CN− toxicity 1349.7 Challenges associated with CN−monitoring 140 9.8 Safe use of SNP – clinical monitoring 1419.9 Prevention and treatment of CN−toxicity 142 9.10 Conclusions 146 9.11 Disclosure 146 References 146 10 Smoke inhalation 151Alan H. Hall and Stephen W. Borron 10.1 Introduction 151 10.2 Cyanide in smoke inhalation 152 10.3 Plasma lactate levels as a screening assay 154 10.4 Exhaled breath cyanide meters 154 10.5 Cobinamide colorimetric quantitative/qualitative blood cyanide measurements 154 10.6 Additional information 154 References 156 11 Occupational exposure to cyanide 158Tee L. Guidotti 11.1 Introduction 158 11.2 Firefighters 159 11.3 Hazmat and counter-terrorism 161 11.4 Other occupations 162 11.5 Illicit operations using cyanide 163 References 164 12 Cyanogenic aliphatic nitriles 166Stephen W. Borron 12.1 Overview 166 12.2 Toxicology 166 12.3 Case reports of human toxicity of specific nitriles 172 12.4 Antidotal treatment 178 12.5 Summary 179 Acknowledgments 179 References 17913 The special case of acrylonitrile (CH2=CH–C≡N) 181Dana B. Mirkin 13.1 Introduction – clinical vignettes 181 13.2 Physical and chemical properties 182 13.3 History – preparation – manufacture 182 13.4 Occurrence 183 13.5 Compounds and uses 183 13.6 Hazardous exposures 184 13.7 Toxicokinetics 184 13.8 Mode of action 185 13.9 Clinical effects 186 13.10 Diagnosis – toxicity 189 13.11 Treatment – antidote 190 13.12 Biological monitoring 191 13.13 Exposure limits 191 References 192 14 Cyanide in chemical warfare and terrorism 195René Pita 14.1 Cyanides as chemical warfare agents 195 14.2 Cyanide and chemical terrorism 200 14.3 Conclusions 206 References 206 15 Cyanide-induced neural dysfunction and neurodegeneration 209Gary E. Isom and Joseph L. Borowitz 15.1 Introduction 209 15.2 Cyanide exposure and manifestations of toxicity 210 15.3 Cyanide-induced histotoxic hypoxia and metabolic dysfunction 210 15.4 Neurochemical actions of cyanide in the nervous system 212 15.5 Cyanide-induced brain injury and neurodegeneration 214 15.6 Endogenous cyanide generation in CNS 215 15.7 Cyanide-induced neurological disorders 216 15.8 Conclusion 220 References 220 16 Cyanides and cardiotoxicity 224J.-L. Fortin, T. Desmettre, P. Luporsi, and G. Capellier 16.1 Introduction 224 16.2 Physiopathology 224 16.3 Clinical aspects 226 16.4 Treatment 228 16.5 Conclusion 230 References 230 17 Respiratory effects of cyanide 232A. Eisenkraft, A. Falk, and Y. Bentur 17.1 Background 232 17.2 Mechanisms of the respiratory effects of cyanide 233 17.3 Clinical manifestations and animal studies 238 17.4 Management of cyanide poisoning and its respiratory effects 241 17.5 Conclusion 245 References 245 18 The analysis of cyanide in biological samples 249Brian A. Logue and Brendan L. Mitchell 18.1 Introduction 249 18.2 Biological matrices 249 18.3 Sample storage 251 18.4 Sample preparation 251 18.5 Spectroscopy 252 18.6 Gas chromatography 254 18.7 High-performance liquid chromatography 256 18.8 Capillary electrophoresis 257 18.9 Electrochemical methods 258 18.10 Sensors 258 18.11 Cyanide metabolites 260 18.12 Insights on cyanide analysis 260 References 260 19 Postmortem pathological and biochemical diagnosis of cyanide poisoning 268Daniel Lugassy and Lewis Nelson 19.1 Introduction 268 19.2 Cyanide pathology and antemortem presentation 268 19.3 Exposures 269 19.4 Autopsy features 269 19.5 Biochemical analysis 271 19.6 Risk to autopsy staff 273 References 274 Further reading 275 20 Medicolegal and forensic factors in cyanide poisoning 276Jorn Chi-Chung Yu and Ashraf Mozayani 20.1 Introduction 276 20.2 Forensic practice for the investigation of cyanide poisoning 277 20.3 Discussion 278 20.4 Conclusion 280 References 280 21 Brief overview of mechanisms of cyanide antagonism and cyanide antidotes in current clinical use 283Alan H. Hall 21.1 Introduction 283 21.2 Methemoglobin inducers 283 21.3 Sulfur donors 285 21.4 Direct cyanide chelating agents 285 21.5 Conclusion 286 References 286 22 Cyanide antidotes in clinical use: 4-dimethylaminophenol (4-DMAP) 288Alan H. Hall 22.1 Introduction 288 22.2 Mechanism of action 288 22.3 Experimental data 289 22.4 Published clinical data 289 22.5 Adverse/side effects 290 22.6 Conclusions 291 References 291 23 Cyanide antidotes in clinical use: dicobalt EDTA (Kelocyanor®) 292Alan H. Hall 23.1 Introduction 292 23.2 Mechanism of action 292 23.3 Experimental data 293 23.4 Published clinical data 293 23.5 Adverse/side effects 294 23.6 Conclusions 294 References 294 24 Amyl nitrite sodium nitrite and sodium thiosulfate 296Richard J. Geller 24.1 History and chemistry 296 24.2 Theoretical bases for use/mechanism of action 297 24.3 Pharmacokinetics 299 24.4 How supplied 299 24.5 Indication and dosing of intravenous antidotes 300 24.6 Adverse effects 301 24.7 Conclusions 301 References 301 25 Cyanide antidotes in current clinical use: hydroxocobalamin 304Alan H. Hall and Stephen W. Borron 25.1 Background and historical perspective 304 25.2 Pharmacology 305 25.3 Experimental animal studies 306 25.4 Human experience 306 25.5 Dosage and route of administration 306 25.6 Adverse effects 306 25.7 Laboratory interferences 307 25.8 Comparison with other antidotes 307 25.9 Conclusion 307 References 307 26 Cyanide antidotes in development and new methods to monitor cyanide toxicity 309Matthew Brenner, Sari Mahon-Brenner, Steven E. Patterson, Gary A. Rockwood, and Gerry R. Boss 26.1 Introduction 309 26.2 Cobinamide and sulfanegen 310 26.3 Other cyanide antidotes in development 313 26.4 New research methods to diagnose and monitor cyanide poisoning and therapy 313 26.5 Conclusions 316 References 316 27 Recent perspectives on alpha-ketoglutarate 317R. Bhattacharya 27.1 Introduction 317 27.2 Cyanide toxicity and its treatment 318 27.3 A-KG as a cyanide antidote 318 27.4 The need for an oral antidote 321 27.5 A-KG as an oral antidote 321 27.6 Some key functions of A-KG 323 27.7 Efficacy of A-KG against other toxins 324 27.8 Role of A-KG as a nutritional supplement 324 27.9 Conclusion 325 Acknowledgments 325 References 325 28 Azide poisonings 330Thomas L. Kurt and Wendy Klein-Schwartz 28.1 Introduction 330 28.2 Lack of cyanide antidote efficacy 331 28.3 Uses of sodium azide 331 28.4 Review of reported sodium azide human poisoning cases 331 28.5 Human experimental exposures to sodium azide and hydrazoic acid 332 28.6 Signs and symptoms 332 28.7 Fatal cases 332 28.8 Historical perspective 333 28.9 Mechanism(s) of action 333 28.10 Autopsy findings 333 28.11 Other outcomes 333 28.12 Occupational health issues 333 28.13 Occupational/environmental exposure limits/recommendations 334 28.14 Laboratory evaluation 334 28.15 Conclusion 334 Acknowledgments 334 Conflict of interest 334 References 334 Index 337
£142.95
World Health Organization Inorganic Chromium (III) Compounds
Book Synopsis
£23.46
