Immunology Books
Penguin Books Ltd A Shot to Save the World
Book Synopsis''Thrilling, inspiring and informative page-turner.'' Walter Isaacson, author of The Code BreakerYou know what went wrong.This is the untold story of what went right.Few were ready when a mysterious respiratory illness emerged in Wuhan, China, in January 2020. Politicians, government officials, business leaders and public-health professionals were unprepared for the most devastating pandemic in a century. Many of the world''s biggest drug and vaccine makers were slow to react or couldn''t muster an effective response.It was up to a small group of unlikely and untested scientists and executives to save civilization. A French businessman dismissed by many as a fabulist. A Turkish immigrant with little virus experience. A quirky Midwesterner obsessed with insect cells. A Boston scientist employing questionable techniques. A British scientist resented by his peers. Far from the limelight, each had spent years developing innovatTrade ReviewThe race to develop a COVID vaccine is one of the most exciting dramas in medical history, and A Shot to Save the World is a thrilling account based on great reporting and access to all of the teams. An inspiring and informative page-turner. * Walter Isaacson, author of The Code Breaker *An appropriately breathless account of the business and scientific rivalries between researchers and companies behind the successful coronavirus vaccines. Zuckerman shows how a global catastrophe transformed the fortunes of tiny, visionary ventures, and huge pharmaceutical enterprises, as they raced to stem the pandemic's spread. -- Andrew Hill * Financial Times *Zuckerman conveys decades of complex scientific research in a gripping fashion. His focus on the slow burn of discovery makes for a fascinating angle and offers plenty of inspiration. The result is tough to put down. * Publishers Weekly *
£18.00
Springer Science+Business Media Psychoneuroimmunology An Interdisciplinary
Book SynopsisPsychoneuroimmunology is the first textbook to examine the complex functional relationships between the nervous system, the neuroendocrine and the immune system. The international leaders in this field have been brought together to create this pioneering text; each contributing from their area of expertise. The result is a comprehensive yet accessible interdisciplinary introduction to psychoneuroimmunology which also takes you further than the foundations of those fascinating topics by covering the most recent research in HIV/AIDS, autoimmune diseases, and the reactivation of latent herpes viruses. Attention is also given to the effects of behavior such as physical exercise, sleep, acute and chronic stress, and conditioning of immune functions in animals and humans. The whole is brought together with a wealth of cited research studies, and over 200 illuTable of Contents1.Functional Anatomy of the Immune System; J. Westermann, M.S. Exton. 2.Foundations in Immunology; R. Jacobs, R.E. Schmidt. 3.Principles of Endocrinology; T. H. Schürmeyer, E. J. Wickings. 4.Concepts in Psychology; U.Tewes. 5 Psychological Methods; U.Tewes, M. Schedlowski. 6.Endocrinological Methods; T. H. Schürmeyer, E. J. Wickings. 7.Methods in Immunology; R. Jacobs. 8. Molecular Anatomical Basis of Interactions between Nervous and Immune Systems in Health and Disease; E. Weihe, et al. 9.Neuroendocrine System and Immune Functions; M. Schedlowski, R. J. Benschop. 10. Opioid Peptide Production by the Immune System; C. J. Heijnen, A. Kavelaars. 11.The Immune-Neuroendocrine Network; H. O. Besedovsky, A. del Rey. 12.Sickness Behavior: A Neuroimmune-Based Response to Infectious Disease; R. Dantzer. 13.Stress Effects on Immune Function in Rodents; M. K. Demetrikopoulos, et al. 14.Behavior/Immune Relationships in Nonhuman Primates; M. L. Laudenslager, J. M. Worlein. 15.Acute Psychological Stress; R. J. Benshop, M. Schedlowski. 16.Concepts and Models of Immunological Change during Prolonged Stress; C. L. Coe. 17.Does Psychological Depression Cause Immune Suppression in Humans? M. Irwin, E. Friedman. 18.Exercise and Immune Functions; B. Klarlund Pedersen. 19.Biobehavioral Influences on Respiratory Immunity; J. Kugler. 20.Effects of PsychosocialInterventions on the Immune System; M. E. Kemeny, G. Miller. 21.Sleep and Immune Functions; J. Born. 22.Functional Relationship between the Olfactory and Immune Systems; F. Eggert, R. Ferstl. 23.Behavioral Conditioning of Immunity; M. S. Exton, et al. 24.Psychoneuroimmunology in Oncology; D. H. Bovbjerg, et al. 25.Psychoneuroimmunology and HIV/AIDS; N. Schneiderman, et al. 26.Psychoneuroimmunology and Autoimmune Diseases; A. Kavelaars, et al. 27.The Effects of Stress on the Immune System: Implications for Reactivation of Latent Herpesviruses; K. L. Applegate, et al. References. Index
£143.99
Hachette Books Long Illness
Book Synopsis
£22.50
Hachette Books Super Gut
Book Synopsis
£22.50
Little, Brown Spark The Immunotype Breakthrough
Book Synopsis
£21.00
Little Brown and Company The Inward Empire Mapping the Wilds of Mortality
Book Synopsis
£20.25
Elsevier Health Sciences Climate Change and Allergy An Issue of Immunology and Allergy Clinics of North America
£70.19
Elsevier - Health Sciences Division Allergy Essentials
Book SynopsisTrade ReviewDoody's Core Titles® 2022 "This book covers diagnosis and management of allergic diseases with emphasis on new therapies. Primary care providers and other specialists who care for allergic patients will find this collection a valuable reference book." ©Doody's Review Service, 2022, Massoud Mahmoudi, DO, PhD (University of California San Francisco)Table of ContentsTentative: 1 Introduction to Mechanisms of Allergic Disease 2 Origins of Allergic Disease 3 Epidemiology of Allergic Disease 4 Indoor and Outdoor Allergens and Pollutants 5 Principles of Allergy Diagnosis 6 Allergen-Specific Immunotherapy 7 Asthma 8 Allergic Rhinitis and Conjunctivitis 9 Drug Allergy 10 Urticaria and Angioedema Without Wheals 11 Atopic Dermatitis and Allergic Contact Dermatitis 12 Food Allergy and Gastrointestinal Syndromes 13 Anaphalaxis 14 Occupational Allergy 15 Insect Allergy
£89.09
Elsevier Science & Technology Infection and Autoimmunity
Book SynopsisTable of Contents1. Introduction Part 1: Mechanisms of Autoimmunity induction by infectious agents and vaccination 2. Molecular Mimicry and Autoimmunity 3. Epitope Spreading in Autoimmune Diseases 4. The immune neuroendocrine system, infections, and rheumatic diseases 5. CD5-Expressing B-1 Cells and Infection 6. Lymphocytes and Infection in Autoimmune Diseases 7. Endothelial Cell Autoreactivity and Infection 8. Microbiota and Autoimmunity 9. Infection, Autoimmunity, and Vitamin D 10. Seasonality and Autoimmunity 11. The Protective Role of Helminths in Autoimmunity 12. Vaccination and Autoimmunity 13. BCG Vaccination 14. Opportunistic Infections and Autoimmune Diseases 15. Can Antibiotics Cure Autoimmune Diseases? Part 2: Viruses and Autoimmunity 16. Anti-Viral Therapy, Epstein–Barr Virus, Autoimmunity, and Chaos (The Butterfly Effect) 17. Roles for Cytomegalovirus in Infection, Inflammation, and Autoimmunity 18. Hepatitis C and Mixed Cryoglobulinemia: An Update 19. HIV Spectrum and Autoimmune Diseases 20. Parvovirus Infection and Its Association with Autoimmune Diseases 21. Human T-lymphotropic Virus Type 1 and Rheumatic Diseases: A Link Between Infection and Autoimmunity 22. Sjögren’s Syndrome: Role of Viruses and Viral-Like Sequences 23. Viral Infection and Heart Disease: Autoimmune Mechanisms 24. Celiac Disease and Rotavirus Infection 25. Theiler’s Murine Encephalomyelitis Virus-Induced Demyelinating Disease (TMEV-IDD) and Autoimmunity Part 3: Bacteria and Autoimmunity 26. Rheumatic Fever: How Streptococcal Throat Infection Triggers an Autoimmune Disease 27. Helicobacter pylori Infection and Gastric Autoimmunity: Coincidence or a Cause and Effect Relationship? 28. Multiple Sclerosis and Creutzfeldt–Jakob Disease are Autoimmune Diseases Probably Caused by Exposure to the Nasal Microbe Acinetobacter 29. Infection and Autoimmunity in Antibiotic-Refractory Lyme Arthritis 30. Streptococcus Pneumoniae and Autoimmunity: A Systematic Review of the Literature: How Pneumococcal Infection Might Be Related to Rheumatic Diseases 31. Mycobacteria and Autoimmunity 32. Mycobacterium avium Subspecies Paratuberculosis and Human Disease: Bridging Infection and Autoimmunity 33. Leprosy and Autoimmunity Part 4: Parasites and autoimmunity 34. Parasitic Infection and Autoimmunity 35. Toxoplasma and Autoimmunity 36. Malaria and Systemic Lupus Erythematosus: Complex Interactions and Reciprocal Influences Part 5: Autoimmune diseases and infections 37. Anti-Saccharomyces cerevisiae Antibodies Autoimmune Diseases 38. The Infectious Origin of the Anti-Phospholipid Syndrome 39. Infections and Systemic Lupus Erythematosus 40. Infections and Idiopathic Inflammatory Myopathies 41. Rheumatoid Arthritis and Infections: More Than an Association? 42. Infection and Systemic Sclerosis 43. Infection and Spondyloarthropathies 44. Infection and Behçet Disease 45. Vasculitides and Hepatitis C Infection 46. The Role of Infection in Inflammatory Bowel Disease: Initiation, Exacerbation and Protection 47. Post-Infectious Arthritis and Reactive Arthritis 48. Infection and Autoimmune Liver Diseases 49. The Role of infection in Immune-mediated Thrombocytopenia 50. Viral Infections and Type 1 Diabetes 51. Infection and Autoimmune Thyroid Diseases 52. Pemphigus and Infection 53. Infections and Autoimmune Renal Diseases 54. Infections Associated with Retinal Autoimmunity 55. Oral Infections and Autoimmune Diseases 56. infection and Guillain–Barré Syndrome 57. Acute Disseminated Encephalomyelitis Part 6: COVID-19 and autoimmunity SARS-CoV-2 (COVID-19) and Autoimmunity 58. COVID-19 and autoimmunity 59. COVID-19 and autoantibodies 60. COVID-19 and vasculitis 61. COVID-19 vaccines and autoimmunity
£199.75
Little, Brown Book Group How Vaccines Work
Book SynopsisVaccines are a debate, whether we want them to be or not. Now more than ever, it''s easy to feel overwhelmed by the accusations and arguments that bloom across the news and internet.With a blend of science and history, HOW VACCINES WORK demystifies the strange and intricate world of vaccines: it explains what a vaccine is, how they are discovered and developed, and what happens when they meet our bodies.With over two decades of experience as an immunologist, David Miles gives expert insight into each vaccine routinely used in Britain, how they have kept us healthy, and why many people have come to worry about possible side effects. Through thrilling storytelling and in-depth exploration of the most common vaccination myths, HOW VACCINES WORK is the perfect guide to understanding all the vaccines we currently receive.Trade ReviewA very good combination of the history of current vaccines and an explanation of what they do and how they do it. As a book for the lay public it is exceptional and I would recommend it to any prospective vaccine recipient or parent -- Stanley A Plotkin, Emeritus Professor of Pediatrics, University of Pennsylvania
£15.29
Little, Brown Book Group How to Stay Healthy
Book SynopsisAn essential guide to optimising your immunity and feeling your best - all year roundThousands of us are struck down by colds, flu and other viruses every year. We know we should be taking steps to look after our immune system every day, but beyond taking vitamin C and getting a good night''s sleep it''s often difficult to know where to start.In How to Stay Healthy, registered nutritionist Jenna Hope provides an easy-to-follow guide that will show you the steps you need to take to optimise your immunity and feel at your best.Through well-explained science this book will help you to understand what the immune system is, why it is so important and how to keep it functioning well in a way that suits you. It will cover the impact of nutrition, gut health and the role of supplements on your immune system, as well as lifestyle factors including smoking, physical activity, sleep, stress and pollution. Hope''s smart, simple and sustainable approach will show you easy ways to incorporate immunity friendly foods into your diet, quick tips for when you''re feeling run down and guidance to set you on the road to recovery from illness.Looking after your immune system has never been more important. This book provides the expert advice you need to do just that.
£13.59
Taylor & Francis Ltd Case Studies in Infectious Disease
Book SynopsisCase Studies in Infectious Disease presents 40 case studies featuring the most important human infectious diseases worldwide. Fully revised and updated in this second edition, the book describes the natural history of infection from point of entry of the pathogen through to clinical management of the resulting disease or condition. A further 8 case studies have been provided online as supplementary material, and these can be downloaded by students. Five core sets of questions are posed in each case, with the answers covering the nature of the infectious agent, route(s) of spread and of infection, pathogenesis of disease, host response to infection, clinical manifestations, diagnosis, treatment and prevention. This standardized approach provides the reader with a logical basis for understanding these diverse and medically important organisms and diseases, fully integrating microbiology and immunology throughout.KEY FEATURES High-resolution photos accompany each case, from the causative agents of disease to the clinical manifestations of the infection. Exquisite artwork helps to illustrate important concepts throughout the book. Eight new cases added to this new edition, extending coverage of important infectious diseases of worldwide significance. A standardized set of core questions allows students to compare directly differences between microbes such as their structure, clinical manifestations, host response, pathogenesis and availability of vaccines. Questions and answers available online, test the readerâs understanding of each case study. The book provides essential case-based learning for undergraduate and graduate microbiology students, while medical students and trainee physicians will also find the up-to-date information on 48 globally important infectious diseases outlined in a clear, digestible form, invaluable during undergraduate studies and in future clinical practice. Trade Review"a handsome, excellent book on most common pathogens, with a clear orientation to immunology, physiopathology, and microbiology … It reads well and is an excellent textbook for medical students and a good source of illustrations, tables, and question ideas for teachers." Gary P. Wormser and Guillaume Béraud for Clinical Infectious Diseases."a valuable compilation of information on the most common diseases that cause illness and death worldwide. The presentation format with distinct sections makes it readable and well suited for either students just learning about the pathogens causing infectious disease or clinicians who need an update. The level of detail is well thought out and gives the reader a useful summary of each pathogen and disease state. The condensed presentations make it a good reference source for those with insufficient time to read through more detailed textbooks." Philip S. Brachman for Emerging Infectious Disease.Table of ContentsAspergillus fumigatus Borrelia burgdorferi and related species Campylobacter jejuni Candida albicansChlamydia trachomatis Clostridiodies difficile Cytomegalovirus Echinococcus spp. EnterovirusesEpstein-Barr virus Escherichia coli Giardia lamblia Helicobacter pylori Hepatitis B virus Hepatitis C virusHerpes simplex virus Histoplasma capsulatum Human immunodeficiency virus Influenza virus Leishmania spp. Leptospira spp. Listeria monocytogenes Mycobacterium leprae Mycobacterium tuberculosis Neisseria gonorrhoeae Neisseria meningitidis Norovirus Plasmodium spp. Respiratory syncytial virus Rickettsia spp. Salmonella typhi Schistosoma spp. Staphylococcus aureus Streptococcus pneumoniae Streptococcus pyogenes Toxoplasma gondii Trypanosoma spp.Trichophyton spp. and dermatophytesVaricella-zoster virus Wuchereria bancrofti Plus online cases:Bartonella bacilliformis BrucellaCoxiella burnetti Dengue virusEnterococcus faecalis and E. faeciumMycobacterium abscessusSARS-CoV-2 Streptococcus mitis
£114.00
W. W. Norton & Company The Immune System
Book Synopsis
£117.80
Penguin Putnam Inc The Invisible Kingdom
Book SynopsisA NEW YORK TIMES BESTSELLERFINALIST FOR THE 2022 NATIONAL BOOK AWARD FOR NONFICTIONNamed one of the BEST BOOKS OF 2022 by NPR, The New Yorker, Time, and Vogue“Remarkable.” –Andrew Solomon, The New York Times Book ReviewAt once a rigorous work of scholarship and a radical act of empathy.”—EsquireA ray of light into those isolated cocoons of darkness that, at one time or another, may afflict us all.” —The Wall Street JournalEssential.—The Boston GlobeA landmark exploration of one of the most consequential and mysterious issues of our time: the rise of chronic illness and autoimmune diseasesA silent epidemic of chronic illnesses afflicts tens of millions of Americans: these are diseases that are poorly understood, frequently marginalized, and can go undiagnosed and unr
£14.40
Taylor & Francis Ltd Tumor Immunology Molecularly Defined Antigens and
Book SynopsisAn introductory overview of the immunology of cancer including therapeutic approaches, this book will be an invaluable source for clinicians, researchers and students of immunology and molecular biology.Table of ContentsIntroduction. Immune Recognition of Cancer-Tumor Antigens. Processing and Presentation of Antigen for the Activation of Lymphocytes. Cellular Recognition of Tumors by T and NK Cells. Humoral Recognition of Cancer. Immunotherapy of Cancer. Tumor Evasion of Immune System.
£109.25
Taylor & Francis Ltd The Antibodies Vol 7 The Antibodies Series
Book SynopsisFrom diagnostic tools to therapy against cancer, infections and autoimmune diseases, antibodies serve many purposes, yet our knowledge of them is still incomplete. The Antibodies: Volume 7 continues with a comprehensive review of topics of contemporary interest including major breakthroughs such as the advent of monoclonal antibodies and the development of new techniques of antibody engineering that have kept antibodies at the forefront of immunology and medical science. While examining the ground-breaking discoveries of the last two decades this book also revisits more traditional aspects of the field to give an holistic approach to this increasingly popular area of medicine.Table of ContentsPositive Selection of B Cell Repertoire, Idiotype Networks and Immunological Memory. The Utility of Immunoglobulins Fusions in DNA Immunisation. Constraints on the Hydropathicity and Sequence Composition of HCDR3 are Conserved Across Evolution. Molecular Aspects of Anti-Polysaccharide Antibody Responses. Molecular Farming Antibodies in Plants: From Antibody Engineering to Antibody Production.
£194.75
Taylor & Francis Ltd Tumor Antigens Recognized by T Cells and
Book SynopsisRecent progress in fundamental tumor immunology has led to immunotherapy trials in patients with solid tumors and hematological malignancies. In the past, immunotherapy approaches were primarily based on enhancement of tumor immunity with cytokines and adjuvant therapy, without knowledge of relevant tumor antigens. The discovery of tumor antigens capable of eliciting immune responses has now resulted in the development of antigen-specific immunotherapy strategies. Vaccination with defined peptide epitopes, purified proteins, cell components, and whole cells expressing defined tumor antigens provides an opportunity to measure antigen-specific immune responses in vaccinated patients, and to correlate immunity with clinical outcome.Tumor Antigens Recognized by T Cells and Antibodies provides a comprehensive overview of the molecular nature of tumor antigens that can be recognized by antibodies, helper T lymphocytes and cytotoxic T lymphocytes. Novel strategies to enhance ineffectiTable of ContentsTumor Antigens Recognized by Antibodies. Human Tumor Antigens Recognized by Antibodies (SEREX). Antibodies to Tumor Oncoproteins in Cancer Patients. Antibody and CTL Responses to the NY-ESO Antigen. Tumor Antigens Recognized by CD4+ T Cells (predominantly TH1). Melanoma Antigens Recognized by CD4+ T Cells. Mouse Models in the Recognition of Tumor Antigens. Antigens of the MAGE Family Recognized by CD4+ T Cells. Tumor antigens Recognized by CD8 T Cells. Melanoma Antigens Recognized by CD8 T Cells. Squamous Cells and Adeno Cancer Antigens Recognized by T Cells. Heat/Shock Proteins and Tumor Antigens. The Wilms Tumor Antigens as CTL Target. Ex vivo and in situ Tetramer Analysis of CTL Responses to Tumors. Altered Peptide Ligands of Tumor T Cell Epitopes: Implications for More Effective Vaccine Therapy in Human Neoplasia.
£166.25
Taylor & Francis Ltd BIOS Instant Notes in Immunology
Book SynopsisBIOS Instant Notes in Immunology, Third Edition, is the perfect text for undergraduates looking for a concise introduction to the subject, or a study guide to use before examinations. Each topic begins with a summary of essential facts-an ideal revision checklist-followed by a description of the subject that focuses on core information, with clear, simple diagrams that are easy for students to understand and recall in essays and exams. BIOS Instant Notes in Immunology, Third Edition, is fully up-to-date and covers: Overview of the Immune System Cells and Molecules of the Innate Immune System The Adaptive Immune System Antibodies The Antibody Response The T Cell Response Cell-Mediated Immunity Regulation of the Immune Response Immunity to Infection Vaccination Immunodeficiency when the Immune System Fails Hypersensitivity whTrade ReviewWhile this guide cannot provide the detail of a text book such as Janeway’s Immunobiology, the third edition of Immunology surely deserves a place upon every immunologist’s bookshelf as an affordable and concise overview of the entire field, something which every biologist should revise every now and again. --Laura J. Carney, School of Medical Sciences, University of Bristol, UK While this guide cannot provide the detail of a text book such as Janeway’s Immunobiology, the third edition of Immunology surely deserves a place upon every immunologist’s bookshelf as an affordable and concise overview of the entire field, something which every biologist should revise every now and again. --Laura J. Carney, School of Medical Sciences, University of Bristol, UK If you're looking for an outline of immunology for studying, this book would be a good choice. It is easy to read and hits the high points covered by multiple choice questions on exams. --Doody's Book Reviews Table of ContentsA. Overview of the immune systemB. Cells and molecules of the innate immune systemC. The adaptive immune systemD. AntibodiesE. The antibody responseF. The T cell response – cell-mediated immunityG. Regulation of the immune responseH. Immunity to infectionI. VaccinationJ. Immunodeficiency – when the immune system failsK. Hypersensitivity – when the immune system misbehavesL. Autoimmunity and autoimmune diseasesM. TransplantationN. Tumor immunologyO. Gender and the immune systemP. Aging and the immune system (immunosenescence)Q. Immunotherapy
£24.69
Elsevier Science Metabolites as Signals in Immunity and
Book Synopsis
£120.60
Elsevier Health Sciences Immunology
Book Synopsis
£50.39
Elsevier Health Sciences Crash Course Haematology and Immunology
Book Synopsis
£31.34
John Wiley and Sons Ltd Vaccinology
Book SynopsisVaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines.Trade Review“It can also serve as a useful reference for practicing physicians and veterinarians who would like to “boost” their knowledge of vaccines.” (Clinical Infectious Diseases, 6 October 2015)Table of ContentsContributors vii Preface ix 1 The history of vaccine development and the diseases vaccines prevent 1Martin G. Myers 2 The vaccine development pathway 33David W.C. Beasley 3 Control and eradication of human and animal diseases by vaccination 43Nigel Bourne and Gregg N. Milligan 4 Pathogenesis of infectious diseases and mechanisms of immunity 59Jere W. McBride and David H. Walker 5 The host immune response protective immunity and correlates of protection 73Gregg N. Milligan 6 Adjuvants: making vaccines immunogenic 93Gregg N. Milligan 7 Discovery and the basic science phase of vaccine development 109Gavin C. Bowick 8 Microbial-based and material-based vaccine delivery systems 127Alfredo G. Torres, Jai S. Rudra and Gregg N. Milligan 9 Licensed vaccines for humans 152Alan D.T. Barrett 10 Veterinary vaccines 181A. Paige Adams 11 Development of vaccines for microbial diseases 192Dennis W. Trent and David W.C. Beasley 12 The regulatory path to vaccine licensure 212Dennis W. Trent 13 Veterinary vaccines: regulations and impact on emerging infectious diseases 232A. Paige Adams 14 Vaccine manufacturing 243Dirk E. Teuwen and Alan D.T. Barrett 15 Clinical evaluation of vaccines 260Richard E. Rupp and Bridget E. Hawkins 16 Vaccine recommendations and special populations 273Richard E. Rupp and Bridget E. Hawkins 17 Vaccine safety 287Dirk E. Teuwen and Alan D.T. Barrett 18 Understanding and measuring the dynamics of infectious disease transmission 304Christine M. Arcari 19 Vaccines from a global perspective 319Alan D.T. Barrett and Bridget E. Hawkins 20 Political ethical social and psychological aspects of vaccinology 335Caroline M. Poland, Robert M. Jacobson, Douglas J. Opel, Edgar K. Marcuse and Gregory A. Poland Index 358
£80.96
John Wiley and Sons Ltd Transplant Immunology
Book SynopsisWith all the complex issues of acceptance or rejection of a transplanted organ, immunology is a key subject for all transplantation clinicians. During recent years, there has been an explosion of research and knowledge in this area.Table of ContentsContributors, vii Foreword, xii Preface, xiv About the companion website, xv 1 Tissues and organs of the immune system, 1Isam W. Nasr, Qiang Zeng, and Fadi G. Lakkis 2 Cells of the immune system, 25Jason R. Lees, Agnes M. Azimzadeh, Yaozhong Ding, Tonya J. Webb, and Jonathan S. Bromberg 3 Soluble mediators in the immune system, 48Charles A. Su, William M. Baldwin III, and Robert L. Fairchild 4 Costimulatory molecules, 65Maria]Luisa Alegre and Anita S. Chong 5 Major histocompatibility complex, 85Raja Rajalingam, Qiuheng Zhang, J. Michael Cecka, and Elaine F. Reed 6 T cells and the principles of immune responses, 103Jonathan S. Maltzman, Angus Thomson, and David M. Rothstein 7 Ischemia and reperfusion injury, 128Yuan Zhai, Yoichiro Uchida, Bibo Ke, Haofeng Ji, and Jerzy W. Kupiec]Weglinski 8 Immune responses to transplants, 142Denise J. Lo and Allan D. Kirk 9 Principles of hematopoietic cell transplantation, 164Sung Choi and Pavan Reddy 10 Therapeutic approaches to organ transplantation, 184Philip F. Halloran, Chatchai Kreepala, Gunilla Einecke, Alexandre Loupy, and Joana Sellarés 11 Organ]specific features in clinical transplantation, 217Roslyn B. Mannon 12 Transplant]related complications, 237Leonardo V. Riella and Anil Chandraker 13 Biomarkers of allograft rejection and tolerance, 259Choli Hartono, Thangamani Muthukumar, and Manikkam Suthanthiran 14 Emerging issues in transplantation, 280Rupert Oberhuber, Guangxiang Liu, Timm Heinbokel, and Stefan G. Tullius 15 New frontiers and new technologies, 297Haval Shirwan, Yiming Huang, Kadiyala Ravindra, and Suzanne T. Ildstad 16 Experimental models in discovery and translational studies, 316Andrew B. Adams, William H. Kitchens, and Kenneth A. Newell Index, 337
£62.96
John Wiley and Sons Ltd Immunology at a Glance
Book SynopsisImmunology at a Glance provides a user-friendly overview of the body s defence mechanisms.Trade Review“This book provides a user-friendly overview of the body’s defence mechanisms. Ideal for a medical, biomedical or life science course, the text contains a basic overview of both adaptive and innate immunity, applied immunological concepts, and how each body system can be affected by immunity.” (European Journal of Immunology, 1 December 2012) Table of ContentsPreface 6 Acknowledgements 6 Note on the tenth edition 6 How to use this book 7 Further reading 7 List of abbreviations 8 Immunity 1 The scope of immunology 10 2 Innate and adaptive immune mechanisms 12 3 Recognition and receptors: the keys to immunity 14 4 Cells involved in immunity: the haemopoietic system 16 Innate immunity 5 Receptors of the innate immune system 18 6 Complement 20 7 Acute inflammation 22 8 Phagocytic cells and the reticuloendothelial system 24 9 Phagocytosis 26 Adaptive immunity (i) The molecular basis 10 Evolution of recognition molecules: the immunoglobulin superfamily 28 11 The major histocompatibility complex 30 12 The T-cell receptor 32 13 Antibody diversification and synthesis 34 14 Antibody structure and function 36 (ii) The cellular basis 15 Lymphocytes 38 16 Primary lymphoid organs and lymphopoiesis 40 17 Secondary lymphoid organs and lymphocyte traffic 42 (iii) The adaptive immune response 18 Antigen processing and presentation 44 19 The antibody response 46 20 Antigen – antibody interaction and immune complexes 48 21 Cell-mediated immune responses 50 (iv) Regulation 22 Tolerance 52 23 Cell communication and cytokines 54 24 The cytokine network 56 25 Immunity, hormones and the brain 58 Potentially useful immunity 26 Antimicrobial immunity: a general scheme 60 27 Immunity to viruses 62 28 HIV and AIDS 64 29 Immunity to bacteria 66 30 Immunity to fungi and ectoparasites 68 31 Immunity to protozoa 70 32 Immunity to worms 72 Undesirable effects of immunity 33 Immunodeficiency 74 34 Harmful immunity: a general scheme 76 35 Allergy and anaphylaxis 78 36 Immune complexes, complement and disease 80 37 Chronic and cell-mediated inflammation 82 38 Autoimmune disease 84 Altered immunity 39 Transplant rejection 86 40 Immunosuppression 88 41 Immunostimulation and vaccination 90 Immunity in health and disease 42 Cancer immunology 92 43 Immunity and clinical medicine 94 44 Investigating immunity 96 45 Immunology in the laboratory 98 46 Out of the past: evolution of immune mechanisms 100 47 Into the future: immunology in the age of genomics 102 Self-assessment Self-assessment questions 105 Answers 107 Appendices Appendix I Comparative sizes and molecular weights 109 Appendix II Landmarks in the history of immunology and some unsolved problems 111 Appendix III CD classification 113 Index 115
£29.40
John Wiley & Sons Inc Gastroenteritis Viruses No 238 Novartis
Book SynopsisThis important book covers the structure and molecular biology of small round structured viruses (SSRVs) such as caliciviruses and astroviruses, and the basic pathology of infection. It provides readers with the knowledge needed to make progress in the prevention and treatment of these infections.Table of ContentsIntroduction (M. Estes). Gastroenteritis Viruses: An Overview (R. Glass, et al.). Structural Studies on Gastroenteritis Viruses (B. Prasad, et al.). Early Events of Rotavirus Infection: The Search for the Receptor(s) (C. Arias, et al.). Rotavirus RNA Replication and Gene Expression (J. Patton). Pathogenesis of Rotavirus Gastroenteritis (M. Estes, et al.). Correlates of Protection Against Rotavirus Infection and Disease (P. Offit). Rotavirus Epidemiology and Surveillance (U. Desselberger, et al.). A Rotavirus Vaccine for Prevention of Severe Diarrhoea of Infants and Young Children: Development, Utilization and Withdrawal (A. Kapikian). The Molecular Biology of Human Caliciviruses (I. Clarke & P. Lambden). Molecular Epidemiology of Human Enteric Caliciviruses in The Netherlands (M. Koopmans, et al.). Molecular Biology of Astroviruses: Selected Highlights (S. Matsui, et al.). Molecular Epidemiology of Human Astroviruses (S. Monroe, et al.). Enteric Infections with Coronaviruses and Toroviruses (K. Holmes). Viruses Causing Diarrhoea in AIDS (R. Pollok). Treatment of Gestrointestinal Viruses (M. Farthing). Summing-Up (M. Estes). Index of Contributors. Subject Index.
£89.06
John Wiley & Sons Inc Applications of Fluorescence in Immunoassays
Book SynopsisDescribes the basic prerequisities for a fluorometric immunoassay: the antibody, the immunological technology, the fluorescent probe, and the instrument. Provides a profile of the clinical applications of the various assay technologies.Table of ContentsAntibodies as Analytical Reagents. Evolution of Immunoassays. Non-Isotopic Immunoassays. Photoluminescence Spectroscopy. Instruments in Fluorometric Immunoassays. Photoluminescent Probes. Fluorescence Immunoassays. Fluorometric Enzyme Immunoassays. Other Specific Binding Assays Using Fluorescence. Multiparametric Immunoassays. References. Index.
£268.15
John Wiley & Sons Inc Immunology A Foundation Text
Book SynopsisThis book provides an integrated approach to the study of immunology for people who seek a user-friendly', concise and up-to-date foundation text. There can be few subjects that so obviously demand such an approach. Immunology overlaps with the biological disciplines of biochemistry, cell biology, genetics, physiology, microbiology and parasitology relying on methods and concepts derived from these disciplines, and in turn contributing to them. After describing the components of the immune system, and explaining how they interact, the author goes on to discuss the many important applications of immunology in laboratory techniques and in medicine. In addition to this introductory' material, the book considers new, and likely future developments giving the reader a taste of the rapid rate of progress in this important field. The author's clear and concise text is supported by a wealth of illustrations (most in two-colour), self-assessment questions and a comprehensive index making thiTable of ContentsImmunity to Infection. Innate Immunity. The Cells of Adaptive Immunity. The Molecules of Adaptive Immunity. Collaboration and Escape. Antigens. Applications of Antigen Recognition. Maturation of the Adaptive Response. Regulation of the Immune Response. Disorders of Immunity. Self Assessment Questions (SAQs). Answers to SAQs. Optional Further Reading. Index. Acknowledgements.
£160.16
John Wiley & Sons Inc Immunology
Book SynopsisHow good a representative is the immune system of a laboratory mouse? How may technical obstacles in one immunological model be bypassed by using another? How much progress has been made in the study of defense mechanisms in plants and animals of commercial importance? The answers to these and numerous other questions regarding the immunological similarities which can be detected across various orders, classes, phyla and kingdoms are found in this book. Provides pertinent information on the advances, opportunities and challenges in comparative work.Table of ContentsPlants (J. Metraux). Invertebrates (D. Millar & N. Ratcliffe). Fishes (M. Manning). Amphibians (J. Horton). Reptiles and Birds (R. Jurd). Mammals (R. Turner). Index.
£166.46
University of California Press State of Immunity
Book SynopsisA comprehensive history of the social and political aspects of vaccination in the United States, this work tells the story of how vaccination became a widely accepted public health measure over the course of the twentieth century. It examines the strategies that health officials have used to gain public acceptance of vaccines.Table of ContentsList of Illustrations Foreword by Daniel M. Fox Acknowledgments Introduction: Vaccination Politics and Law in American History 1. Between Persuasion and Compulsion: Vaccination at the Turn of the Twentieth Century 2. Science in a Democracy: Smallpox Vaccination in the Progressive Era and the 1920s 3. Diphtheria Immunization: The Power, and the Limits, of Persuasion 4. Hard Cores and Soft Spots: Selling the Polio Vaccine 5. Eradicationism and Its Discontents 6. Consent, Compulsion, and Compensation: Vaccination Programs in Crisis 7. Expansion and Backlash: Vaccination at the Turn of the Twenty-First Century Notes Archival Sources Index
£56.80
Penguin Young Readers The End of Food Allergy
Book SynopsisA life-changing, research-based program that will end food allergies in children and adults forever.The problem of food allergy is exploding around us. But this book offers the first glimpse of hope with a powerful message: You can work with your family and your doctor to eliminate your food allergy forever.The trailblazing research of Dr. Kari Nadeau at Stanford University reveals that food allergy is not a life sentence, because the immune system can be retrained. Food allergies--from mild hives to life-threatening airway constriction--can be disrupted, slowed, and stopped. The key is a strategy called immunotherapy (IT)--the controlled, gradual reintroduction of an allergen into the body. With innovations that include state-of-the-art therapies targeting specific components of the immune system, Dr. Nadeau and her team have increased the speed and effectiveness of this treatment to a matter of months.New York Times bestselling author Sloan Barnett, the mother of two children with food allergies, provides a lay perspective that helps make Dr. Nadeau's research accessible for everyone. Together, they walk readers through every aspect of food allergy, including how to find the right treatment and how to manage the ongoing fear of allergens that haunts so many sufferers, to give us a clear, supportive plan to combat a major national and global health issue.
£15.30
Harmony/Rodale Chinese Medicine for Maximum Immunity Understanding the Five Elemental Types for Health and WellBeing
Book SynopsisReflecting on the connection between the rise in chronic immune disorders and toxic environmental and lifestyle patterns, herbalist and acupuncturist Jason Elias and collaborator Katherine Ketcham looked to the 5,000-year-old The Yellow Emperor's Classic of Medicine to seek clues for restoring the balance of body and mind. In Chinese Medicine for Maximum Immunity, Elias and Ketcham show how to use the preventive strategies and gentle, supportive remedies of traditional Chinese medicine to heal contemporary chronic illnesses and bolster immunity. The book teaches readers how to identify which element--Wood, Fire, Earth, Metal, and Water--most directly influences them and how to correct imbalances that can lead to particular physical, emotional, and spiritual disorders with step-by-step instruction for using stress-reduction techniques, diet and exercise, herbs, and acupressure.
£17.09
Elsevier Health Sciences Immunology for Medical Students
Book SynopsisTable of ContentsSection 1: Introduction Introduction to the Immune System Basic Concepts and Components of the Immune System Section 2: Antigen-Recognition Molecules 3. Introduction to Antigen Recognition 4. Antigens and Antibody Structure 5. Antibody-Antigen Interaction 6. Antibody Diversity 7. The T-Cell Receptor 8. Major Histocompatibility Complex 9. Review of Antigen Recognition Section 3: Physiology 10. Antigen Processing and Presentation 11. Lymphocyte Activation 12. Hematopoiesis 13. The Organs and Tissues of the Immune System 14. B-Cell Development 15. T-Cell Development 16. T-Cell Interactions and T-Cell Help 17. Immunological Memory and Homeostasis 18. Regulation of the Immune System 19. Brief Review of Immune Physiology Section 4: Innate Immunity 20. Constitutive Defenses Including Complement 21. Phagocytes 22. Killing in the Immune System 23. Inflammation 24. Cytokines in the Immune System Section 5: Immune System in Health and Disease 25. Infections and Vaccines 26. Hypersensitivity Reactions 27. Immediate Hypersensitivity (Type I): Allergy 28. How Autoimmune Disease Develops 29. Antibody-Mediated Hypersensitivity (Type II) 30. Immune Complex Disease (Type III Hypersensitivity) 31. Delayed Hypersensitivity (Type IV) and Review of Hypersensitivity Reactions 32. Primary Immunodeficiency 33. Secondary Immunodeficiency 34. Transplantation 35. Tumor Immunology 36. Bio Pharmaceuticals Glossary Index
£39.89
Elsevier Health Sciences Immunology
Book SynopsisTable of ContentsSECTION 1 The Immune System and Innate Immunity 1 Introduction to the Immune System 2 Cells, Tissues and Organs of the Immune System 3 Mechanisms of Innate Immunity 4 Complement 5 Mononuclear Phagocytes in Immune Defence SECTION 2 Adaptive Immune Responses 6 T-Cell Receptors and Major Histocompatibility Complex Molecules 7 Antigen Presentation 8 Cell-Mediated Cytotoxicity 9 B-Cell Development and the Antibody Response 10 Antibodies 11 Immunological Tolerance 12 Regulation of the Immune Response 13 Immune Responses in Tissues SECTION 3 Defence Against Infectious Agents 14 Immunity to Viruses 15 Immunity to Bacteria and Fungi 16 Immunity to Protozoa and Worms 17 Vaccination SECTION 4 Immunodeficiency 18 Primary Immunodeficiencies 19 AIDS, Secondary Immunodeficiency and Immunosuppression SECTION 5 Immune Responses Against Tissues 20 Autoimmunity and Autoimmune Disease 21 Transplantation and Rejection 22 Immunity to Cancers SECTION 6 Hypersensitivity 23 Immediate Hypersensitivity (Type I) 24 Hypersensitivity (Type II) 25 Hypersensitivity (Type III) 26 Hypersensitivity (Type IV)
£50.34
CRC Press Biology of Disease
Book SynopsisBiology of Disease describes the biology of many of the human disorders and disease that are encountered in a clinical setting. It is designed for first and second year students in biomedical science programs and will also be a highly effective reference for health science professionals as well as being valuable to students beginning medical school. Real cases are used to illustrate the importance of biology in understanding the causes of diseases, as well as in diagnosis and therapy. Trade Review"Overall, the book is an excellent introduction to the subject of pathology, disease and laboratory diagnostics, which would be ideal for undergraduate students on biomedical science and related degrees." - Biochemistry and Molecular Biology Education, 2007"When you first pick up this book and peruse the pages it is immediately encouraging. The presentation and production values are very good, the diagrams and photographs look professional and it is a substantial volume, all of which suggests a worthwhile textbook.""I would have welcomed this book when I started out in the laboratory, as the books at that time were less welcoming and somewhat drier to read. I recommend this book to students and tutors as a text for any course on the biology of disease."British Journal of Biomedical Science, Volume 64, Number 1, 2007"Overall, the book is an excellent introduction to the subject of pathology, disease and laboratory diagnostics, which would be ideal for undergraduate students on biomedical science and related degrees."Biochemistry and Molecular Biology Education, 2007"…an excellent introduction to the subject of pathology, disease and laboratory diagnostics, which would be ideal for undergraduate students on biomedical science and related degrees."Biochemistry and Molecular Biology EducationTable of Contents1. The Nature and Investigation of Diseases 2. Pathogens and Virulence 3. Infectious Diseases and Treatments 4. The Immune System 5. Disorders of the Immune System 6. Transfusion and Transplantation 7. Disorders of the Endocrine System 8. Disorders of Water, Electrolytes and Urate Balances 9. Disorders of Acid-Base Balance 10. Diet and Disease 11. Disorders of the Gastrointestinal Tract, Pancreas, Liver and Gall Bladder 12. Toxicology 13. Disorders of the Blood 14. Disease of the Cardiovascular System 15. Genetic Diseases 16. Membrane, Organelle and Cytoskeletal Disorders 17. Cancer 18. Ageing & Disease. Case Study DiscussionsAnswers to Questions
£50.34
Quarto Publishing Group USA Inc The Immunity Food Fix Cookbook
Book SynopsisThe Immunity Food Fix Cookbook, a follow-up companion to The Immunity Food Fix, offers 75 delectable recipes to boost your immune system.
£15.99
Johns Hopkins University Press When the Diagnosis Is Multiple Sclerosis Help
Book SynopsisThis medically up-to-date and compassionate book offers guidance not only to patients and their families but to healthcare professionals, psychologists, psychiatrists, and physical and occupational therapists.Trade ReviewDr. Furney draws on her own experience and medical expertise to show that life can be lived to the fullest with MS. She covers psychological challenges, having children, handling a career, and staying healthy-all in a readable-over-a-cup-of-coffee kind of way. Unfailingly honest, Dr. Furney shows a very human aspect of the doctor-patient relationship. Momentum Magazine This is an excellent addition to the MS literature, offering hope to patients and helping to educate healthcare professionals about what it is really like being on the other side of the physician-patient encounter. -- Joseph I. Sirven Doody's Review Service 2009Table of ContentsSeries ForewordPrefaceAcknowledgments Chapter 1. Being DiagnosedChapter 2. GrievingChapter 3. The Psychological Challenges of MSChapter 4. Facing the Needle: The MS MedicationsChapter 5. Whom Do I Tell and When?Chapter 6. Impact on Our JobsChapter 7. Having ChildrenChapter 8. Staying Healthy and FitChapter 9. Managing the Fatigue of Multiple SclerosisChapter 10. Could I Be Depressed?Chapter 11. You and Your DoctorChapter 12. Dealing with DisabilityChapter 13. Getting Involved with the MS CommunityChapter 14. Finding BalanceConclusionAppendix: The Facts About MSResourcesReferencesIndex
£22.28
F.A. Davis Company Clinical Immunology Serology
Book SynopsisIncludes coverage of external defenses and inflammation, human microbe relationships, bacterial virulence factors, the role of B and T cells in the adaptive immune response, the immune mechanisms involved in humoral antibody production and cell-mediated immunity, tumor markers, and immune mechanisms.Table of Contents I. Nature of the Immune System 1. Introduction to Immunity and the Immune System 2. Nature of Antigens and the Major Histocompatibility Complex 3. Innate Immunity 4. Adaptive Immunity 5. Antibody Structure and Function 6. . Cytokines 7. Complement System II. Basic Immunological Procedures 8. Safety and Quality Assessment 9. Principles of Serological Testing 10. Precipitation and Agglutination Reactions 11. Immunoassays 12. Molecular Diagnostic Techniques 13. Flow Cytometry and Laboratory Automation III. Immune Disorders 14. Hypersensitivity 15. Autoimmunity 16. Transplantation Immunology 17. Tumor Immunology 18. Immunoproliferative Diseases 19. Immunodeficiency Diseases IV. Serological and Molecular Diagnosis of Infectious Disease 20. Serological and Molecular Detection of Bacterial Infections 21. Spirochete Diseases 22. Serological and Molecular Diagnosis of Parasitic and Fungal Infections 23. Serology and Molecular Detection of Viral Infections 24. Laboratory Diagnosis of HIV Infection 25. Immunization and Vaccines Glossary Answer Key References Index
£78.30
John Wiley and Sons Ltd Immunology
Book SynopsisImmunology: A Concise Review offers the essential and basic ideas of immunology as a quick reference for students, practitioners, and veterinary technicians. Although concise, the book is comprehensive and a knowledge of its contents will assure the reader a relatively thorough understanding of what is frequently a difficult subject. The book covers all of the basics of immunology, including chapters on: the origin and function of hemopoietic and lymphopoietic cells; non-specific immunity; antigens; complement; cell receptors and cytokines associated with the immune response; specific immune responses; responses to bacteria, fungi, protozoa, helminths, and tumors. More advanced topics include: an examination of all four hypersensitivity reactions; autoimmunity; immune deficiency diseases; organ transplant and rejection; vaccination and immunization; and immunodiagnostic techniques. Additionally, the book offers end of chapter glossaries and a cumulative glossary as wTable of ContentsPreface; Abbreviations and Greek Letters; Introducing immunology; The hemopoietic and lymphopoietic cells; natural immunity and resistance; The nature of antigens and immunogens; The complement system; T cell receptors, major histocompatibility complex and cytokines; The humoral immune response; The cell-mediated immune response; The immune system in action; Hypersensitivity reactions, allergy and anaphylaxis; Hypersensitivity reactions, cytotoxic/cytolytic, immune complex and delayed type; Autoimmunity; Immune deficiency diseases; immune deficiency diseases; Transplant/graft rejection; vaccination/immunisation; Immunodiagnostic techniques; Cumulative Glossary; Index
£55.76
Taylor & Francis Inc Case Studies in Allergic Disorders
Book SynopsisCase Studies in Allergic Disorders is designed for undergraduate and graduate students in immunology, medical students, and resident physicians. It describes the basic cellular and molecular mechanisms involved in the pathogenesis of commonly occurring allergic diseases and introduces the rationale for targeted treatment of allergy. Replicating the successful approach of Case Studies in Immunology, the book presents mechanisms of hypersensitivity through a selection of clinical cases that reinforce and extend the basic science. The cases are largely drawn from the records of Children's Hospital Boston. Linking the discussion of pathogenesis to actual clinical presentation establishes important connections between the bench and bedside. The book can be used as either a stand-alone text or asa companion to Janeway's Immunobiology and The Immune System.Trade Review"...Clear, concise, insightful, and useful....[Case Studies in Allergic Disorders] is a genuinely stimulating read for the immunology enthusiast." -- Yale Journal of Biology and Medicine"The authors have succeeded in developing a volume that is useful for teaching immunologic concepts of allergic disease to undergraduate and graduate students, interns, and residents. Overall, Oettgen and Geha have done an admirable job constructing a case-based textbook that will be useful to a diverse audience." --The Quarterly Review of Biology "...Clear, concise, insightful, and useful....[Case Studies in Allergic Disorders] is a genuinely stimulating read for the immunology enthusiast." -- Yale Journal of Biology and Medicine"The authors have succeeded in developing a volume that is useful for teaching immunologic concepts of allergic disease to undergraduate and graduate students, interns, and residents. Overall, Oettgen and Geha have done an admirable job constructing a case-based textbook that will be useful to a diverse audience." --The Quarterly Review of BiologyTable of Contents1. Acute Systemic Anaphylaxis 2. Allergic Asthma 3. Allergic Rhinitis4. Allergic Diseases of the Eye 5. Atopic Dermatitis 6. Contact Sensitivity to Poison Ivy 7. Transfusion Reaction 8. Drug-induced Serum Sickness 9. Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease (IPEX) 10. Hereditary Angioedema11. Urticaria 12. Food Allergy 13. Eosinophilic Esophagitis 14. Allergic Bronchopulmonary Aspergillosis 15. Hypersensitivity Pneumonitis and Occupational Lung Disease 16. Venom Hypersensitivity17. Hypereosinophilic Syndrome 18. Churg-Strauss Syndrome19. Aspirin-Exacerbated Respiratory Disease (AERD) 20. Mastocytosis
£40.84
WW Norton & Co Case Studies in Immunology
Book SynopsisThe perfect clinical companion for your immunology course.Table of Contents1. X-linked Agammaglobulinemia 2. CD40 Ligand Deficiency 3. Activation-Induced Cytidine Deaminase Deficiency 4. Common Variable Immunodeficiency 5. X-linked Severe Combined Immunodeficiency 6. Adenosine Deaminase Deficiency 7. Omenn Syndrome 8. MHC Class II Deficiency 9. DiGeorge Syndrome 10. Acquired Immune Deficiency Syndrome (AIDS) 11. Graft-Versus-Host Disease 12. MHC Class I Deficiency 13. X-linked Lymphoproliferative Syndrome 14. Hemophagocytic Lymphohistiocytosis 15. Chediak–Higashi Syndrome 16. Wiskott-Aldrich Syndrome 17. Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy (APECED) 18. Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease 19. Autoimmune Lymphoproliferative Syndrome (ALPS) 20. Hyper IgE Syndrome21. Ataxia Telangiectasia 22. Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome (WHIM Syndrome) 23. X-linked Hypohidrotic Ectodermal Dysplasia and Immunodeficiency 24. Interferon-γ Receptor Deficiency 25. Severe Congenital Neutropenia 26. Chronic Granulomatous Disease 27. Leukocyte Adhesion Deficiency 28. Recurrent Herpes Simplex Encephalitis 29. Interleukin 1 Receptor-Associated Kinase 4 Deficiency 30. Congenital Asplenia 31. Hereditary Angioedema 32. Deficiency of the C8 Complement Component 33. Hereditary Periodic Fever Syndromes 34. Systemic Juvenile Idiopathic Arthritis 35. Rheumatoid Arthritis 36. Systemic Lupus Erythematosus 37. Systemic Lupus Erythematosus 38. Multiple Sclerosis 39. Autoimmune Hemolytic Anemia 40. Myasthenia Gravis 41. Pemphigus Vulgaris 42. Celiac Disease 43. Acute Infectious Mononucleosis 44. Hemolytic Disease of the Newborn 45. Toxic Shock Syndrome 46. Lepromatous Leprosy 47. Allergic Asthma 48. Drug-induced Serum Sickness 49. Contact Sensitivity to Poison Ivy 50. Dedicator of Cytokinesis 8 Deficiency 51. Activated PI3KD Syndrome (APDS) 52. Increased Susceptibility to Candida Infections 53. LPS-Responsive Beige-Like Anchor (LRBA) Deficiency 54. T Cell Signaling Defects 55. Channelopathies
£41.80
Taylor & Francis Inc The Immunological Basis of Asthma
Book SynopsisThis text assesses the role of dendritic cells, T and B lymphocytes, epithelial and mast cells, eosinophils, neutrophils, macrophages, and their products in the initiation and progression of airway inflammation, regulation, and repair. It unveils advances in immunology and cell biology to generate new therapeutic regimens for inflammatory and allergic diseases,and offers unparalleled research from nearly 60 international contributors.Table of ContentsThe cells of the pulmonary immune response: overview of the pulmonary immune response, Laurent P. Nicod; antigen-presenting cells, Henk C. Hoogsteden, Hamida Hammad, and Bart N. Lambrecht; CD4 T lymphocytes in allergic asthma, Mark Larche and A.B. Kay; B-Cell differentiation and IgE synthesis, Hamida Hammad and Bart N. Lambrecht; immune functions of mast cells and basophils, Sarbjit S. Saini; immune functions of human eosinophils, Paul J. Coffer, Patricia M. R.E. Silva, Marco A. Martins, and Leo Koenderman; immune functions of airway epithelium, Sundeep S. Salvi and Stephen T. Holgate. Regulation processes in the pulmonary immune response: tolerance to inhaled antigen, Elizabeth R. Jarman, Gerard F. Hoyne and Jonathan R. Lamb; sensitization to inhaled allergen, Susan L. Prescott; polarization of T-helper cells, Martien L. Kapsenberg, Eddy A. Wierenga, Pawel Kalinski and Esther C. De Jong; CD28 and B7 superfamily members - costimulation and regulation of T-cell function, Anthony J. Coyle, Stephen Manning, and Jose-Carlos Gutierrez-Ramos; control of lymphocyte trafficking through the lung, Reinhard Pabst and Thomas Tschernig; neuroimmune interactions in the pathogenesis of allergic asthma, Armin Braun, Wolfgang A. Nockher, and Harald Renz. Integrated immunology of airway inflammation: immunopathology of atopic and nonatopic asthma, Marc Humbert, Sun Ying, and Douglas S. Robinson; immunology of eosinophilic airway inflammation - what the animal models teach us, Bart N. Lambrecht, Leonie S. Van Rijt, and Harmjan Kuipers; regulation of cellular traffic in the asthmatic lung, Clare M. Lloyd and Jose-Carlos Gutierrez-Ramos; cytokine regulation of bronchial hyperresponsiveness, Johan C. Kips and Romain A. Pauwels; immunological functions of inflammatory mediators, Domenico Spina, Clive Page, Anthony P. Sampson, and Zuzana Diamant; virally induced eosinophilic airway inflammation, Wieslawa Olszewska and Peter J.M. Openshaw; airway remodelling as the outcome of a chronic immu
£162.00
Taylor & Francis Inc Immune Interferon
Book SynopsisNow for the first time, one comprehensive book summarizes and analyzes the numerous scientific papers and reviews covering selected aspects of the structure, biological activities, and clinical effects of immune interferon, also known as interferon-gamma(IFN-gamma). Immune Interferon: Properties and Clinical Applications is essential reading for anyone working with interferons.Having developed their own brand of interferon-gamma, the authors have become well known for their research and significant contributions in the fields of molecular biology, biochemistry, and interferon-gamma. They bring together the extensive findings from years of research since the discovery of the drug. Focusing on the drug itself and not particular brands, the book presents data on the properties of interferon-gamma, experimental data on its effects in cell cultures in vitro and on animals in vivo, the role that IFN-gamma plays in different diseases, and the results of its clinical applications.<Trade Review"…an excellent review of indications studied and under study and the outcomes of IFNg, as well as an exhaustive collection of references for these indications. A briefer overview of the preclinical and pharmacologic aspects of IFNg is provided."- James E. Talmidge, Ph.D., University of Nebraska Medical School in Doody's NotesTable of ContentsForeword. Abbreviations. The Cytokine Family.Interferon Gamma (IFN). Biological Activities of Interferon Gamma. Molecular Mechanisms of IFN Activities. Transmembrane Signal Transduction. Production of Interferon Gamma. Gamma-Interferon Preparations. Indications and Contraindications. Routes of Administration, Pharmacokinetics, Dosage. Side Effects. Infectious Diseases. Non-Infectious Non-Malignant Diseases. Malignant Diseases. General Conclusions. References.
£237.50
Taylor & Francis Inc Desk Reference for Hematology
Book SynopsisA cross between a dictionary and an encyclopedia, Desk Reference for Hematology, Second Edition presents a concise yet thorough examination of hematology and its relationship with other systems and disorders. The 1500 alphabetically listed articles provide quick and easy access to expert information, the 150 tables put precise data at your fingertips, and the 100 figures are a visual tool that clarify the text. The book also includes 500 references on state-of-the-art guidelines and recent developments.See whatâs new in the Second Edition: Revised articles emphasizing genetics, physiology, pathological mechanisms Updated coverage of treatments for leukemia, lymphoma, coagulation, and thrombotic disorders Hundreds of completely new articles, new illustrations, and new explanatory diagrams as well as revised tables Completely revised, this edition covers hematopoiesis, red blood cells, granulocytes, lymphocytes, platelets and hemostasis where the respective physiology is described anemias, leukemias, lymphomas, auto-immune disorders, hemorrhagic disorders, and thrombosis where etiology, pathogenesis, diagnosis and treatment is described. The book includes coverage of blood groups and the practice of blood component therapy. The editor pays particular attention to recent developments in hematological molecular genetics and leukemogenesis. The information is cross-referenced with words highlighted in bold face within an article to indicate that further information on the subject is available under the emboldened heading. A separate table provides common abbreviations used widely throughout the text. Carefully designed for ease of use, the book provides speedy access to authoritative information on the scientific basis of blood disorders and their treatment.Table of ContentsContents are listed alphabetically by subject.
£228.00
Taylor & Francis Inc Handbook of Animal Models in Transplantation
Book SynopsisHandbook of Animal Models in Transplantation Research is a new surgical handbook that provides detailed information concerning the transplantation of a variety of tissues in experimental animals. The text provides a practical guide for experienced investigators to develop new surgical transplantation models for application in a laboratory setting. Each chapter gives consistent descriptions of the anatomical considerations, the surgical model, and potential applications of the procedure. The organ systems covered include the heart and/or lung, liver, small bowel, kidneys, and bone marrow. The species selected for representation of each experimental model is based upon the usefulness and frequency of the model for studies in transplantation research. This book is important for all experimental surgeons, transplantation biologists, and students of surgical research.Trade Review"This book is an excellent reference for anyone interested in transplant research...a good investment." -Susan Harper, SYNAPSE, 28(4), December 1995Table of ContentsIntroduction (L. Makowka, D.V. Cramer, and L. Podesta). Kidney Transplantation: Renal Transplantation in the Rat (M.H. Sayegh and E.L. Milford). Renal Transplantation in the Rabbit (W. Lopatin, H. Noguchi, and L. Makowka). Kidney Transplantation in Yucatan Miniature Swine (T. Howard, C.A. Cosenza, D.V. Cramer, and L. Makowka). Liver Transplantation: Liver Transplantation in Mice (S. Qian and J.J. Fung). Orthotopic Rat Liver Transplantation (M. Knoop, R. Steffen, D.V. Cramer, and L. Makowka). Liver Transplantation in the Dog (C.E. Broelsch, L. Stevens, and J.B. Piper). Liver Transplantation in the Pig (D. Kahn and R. Hickman). Liver Transplantation in Primates (O. Imventarza, H.L.R. Rilo, A. Oks, J.J. Fung, and T.E. Starzl). Transplantation of Hepatocytes (A.A. Demetriou, J. Rozga, and A.D. Moscioni). Pancreas Transplantation: Whole Pancreas Transplantation in the Rat (M.J. Orloff and M.S. Orloff). Isolation of Pancreatic Islets for Transplantation Studies (C. Ricordi). Heart Transplantation: Heterotopic Heart Transplantation in Rodents (F.A. Chapman, D.V. Cramer, and L. Makowka). Heart, Lung, and Heart-Lung Transplantation in the Dog and the Pig (R. Saito and P. Waters). Heart Transplantation in Primates (D.K.C. Cooper, Y. Ye, and M. Niekrasz). Small Bowel and Multivisceral: Multivisceral Transplantation in the Rat (N. Murase and T.E. Starzl). Intestinal Transplantation in the Rat (D.R. Grant, R. Zhong, and R. Black). Multivisceral Transplantation in the Pig (L. Podesta, D.V. Cramer, and L. Makowka). Bone Marrow and Graft-Versus-Host Disease: Bone Marrow Transplantation and Graft-Versus-Host Disease in Mice (R. Korngold). Bone Marrow Transplantation in Dogs (H.J. Deeg and R. Storb). Bone Marrow Transplantation in the Pig (D.H. Sachs, P. Guzzetta, C.V. Smith, K. Nakajima, and A. Mixon). Xenotransplantation: The Use of Xenografts in Experimental Transplantation (D.V. Cramer and L. Makowka). Immunosuppressive Agents: The Use of Immunosuppressive Agents in Animal Models
£446.50
Taylor & Francis Inc Adenosine Receptors
Book SynopsisAfter a century of research, several lines of evidence now indicate that the ability of adenosine to directly control inflammatory cells has a major impact on the functions of the inflammatory and immune systems. Consequently, many promising therapeutic approaches are beginning to emerge that focus on the modulation of adenosine, including the development of compounds that interfere with the breakdown of adenosine, as well as specific agonists and antagonists of various adenosine subtypes. Some of these compounds have already entered clinical trials. While information on the role of adenosine is growing rapidly, until now it has remained scattered in the literature.Edited by three pioneering researchers in the field, Adenosine Receptors: Therapeutic Aspects for Inflammatory and Immune Diseases presents the first single volume compilation of reviews on how adenosine, acting on its cellular receptors, regulates immune responses. The book is organized to provide the readeTrade Review"… written by a number of prime experts in the field. … highly recommended to readers who are interested in the pharmacology of adenosine receptors." – Christa E. Muller, PharmaCenter Bonn, Germany in ChemMedChem, 3, 2008Table of ContentsIntroduction. Adenosine Receptor Pharmacology. Regulation of Macrophage Function by Adenosine Receptor Engagement. Anti-inflammatory Effects of Inosine. Regulation of Adenosine Receptor Expression in Inflammation. A2a Adenosine Receptors in Ischemia. Adenosine, Toll-like Receptors, and Angiogenesis. Adenosine Signaling and Lung Fibrosis. Adenosine and Endothelial Cell Function. Regulation of Peripheral Inflammation by Spinal Adenosine. Adenosine, Hypoxia, and Immunity. Adenosine Regulation of Dendritic Cell Function. A2b Receptors in Intestinal Epithelial Cells. Adenosine Receptors in Multiple Sclerosis. Adenosine Receptors in Infectious Disease. Adenosine, Tumors, and Immunity. Adenosine in Atherosclerosis. Adenosine in Neuroimmunomodulation.
£237.50
Taylor & Francis Inc Phylogenesis of Immune Functions
Book SynopsisThis volume discusses recent advances in research regarding the evolution of specific and nonspecific defense responses in a taxonomically diverse array of species. Topics regarding invertebrates include the protective mechanisms (cellular and molecular) employed by insects, the protective roles of lectins, and the self-nonself discrimination revealed by tissue incompatibility reactions. With vertebrates, the evolution of the immunoglobulin-related superfamily of recognition molecules (including immunoglobulins and the major histocompatibility complex molecules) is examined over several chapters. Other topics reviewed include the evolution of nonimmunoglobulin mediators of defense (e.g., cytokines and eicosanoids), lymphocyte subpopulations (including effects of ambient temperature on function) and the phylogenetic emergence of natural killer cells. Phylogenesis of Immune Functions provides invaluable information for evolutionary biologists, as well as all immunologists and other reseTable of ContentsOn Immunity and Its Phylogenesis. Adaptive Immune Responses in Insects. Insect Antibacterial Proteins. The Prophenoloxidase System and Its Role in Arthropod Immunity. The Multiple Biological Roles of Invertebrate Lectins: Their Participation in Non-Self Recognition Mechanisms. Historecognition in the Cnidaria. Biological Individuality and Disease: New Perspectives on Immunoevolution. The MHC Molecules of Ectothermic Vertebrates. The Major Histocompatibility Complex of the Chicken. Evolutionary Origins of Immunoglobulin Genes. Evolution of Lymphocyte Subpopulations, Their Interactions and Temperature Sensitivities. Phylogeny of Cytotoxic Cells. The Phylogenetic Conservation of Cytokines. Eicosanoids: Aspects of Their Structure, Function, and Evolution. Mechanisms of Molecular Evolution in the Immunoglobulin Superfamily.
£403.75
Taylor & Francis Inc The Major Histocompatibility Complex Region of
Book SynopsisThe major histocompatibility complex (Mhc) is one of the few identified gene systems in domestic animals that is associated with quantitative traits such as disease resistance, immune response, growth, and reproduction. As knowledge of this important system increases, we move closer toward the reality of genetic enhancement of animal welfare and production efficiency. This book represents the current state of knowledge on the Mhc of agriculturally important animals and explores the latest advances in technology. For the first time, the unique findings of recent Mhc research are presented in a single source.The Major Histocompatibility Complex Region of Domestic Animal Species begins with a discussion of the evolution of Mhc. The chapters are then organized with respect to specific species, with a chapter devoted to each. The Mhc of mice and humans are used as a common reference for comparisons between diverse species. The text concludes with a look at future strategies and directions in Mhc research. Comparative immunologists and geneticists, veterinarians, animal breeders, researchers, and university and postgraduate students will all benefit from this detailed look at the evolution, structure, and organization of Mhc.Table of ContentsMajor Histocompatibility Complex Evolution. The Major Histocompatibility Complex of Fish: Genetic Structure and Function of the Mhc of Teleost Species. The Chicken Major Histocompatibility Complex. Genetic Organization, Polymorphism, and Function of the Bovine Major Histocompatibility Complex. The Caprine Major Histocompatibility Complex. The Ovine Major Histocompatibility Complex. The Cervine Major Histocompatibility Complex: Genetic Structure and Function of the Cervine DRB Genes. The Canine Major Histocompatibility Complex: Genetic Structure and Function of the Mhc of Dogs. The Swine Major Histocompatibility Complex. The Equine Major Histocompatibility Complex. The Major Histocompatibility Complex of the Rabbit. Future Perspectives. Index.
£137.75
Taylor & Francis Inc Manual of Immunological Methods Handbooks in
Book SynopsisThe Manual of Immunological Methods represents the collaboration of the Canadian Network of Toxicology Centers, a non-profit network of university-based scientists dedicated to research, training, risk assessment, and communication. This manual provides detailed immunological methods that can be utilized by researchers or practitioners who want to enhance the successful application of this science. It emphasizes the need for continuously improving the quality of experiments performed and maintaining consistency in the results obtained.The Manual of Immunological Methods presents validated assays that are accompanied by a series of tools that will guide readers in performing their own laboratory work in the spirit of the Good Laboratory Practices. It covers specific methodologies including sample collection, preparation of cells, assay conditions, and data evaluation. Discussion of species differences and comparisons of a wide variety of species is an important feature. Both graduatTable of ContentsIdentification, Anaesthesia, and Euthanasia. Collection of Peripheral Blood Samples. Removal of Organs. Preparation of Cell Suspensions. Assessment of Cell Viability. Cell Cryopreservation. Oxidative Burst Assay Using Flow Cytometry. Cell Cytotoxicity. Lymphoblastic Transformation. Determination of Antibody-Producing Cells to a Specific Antigen. Mixed Lymphocyte Reaction (MLR). Intracellular Levels of Calcium Assay Using Flow Cytometry. Phenotyping of Blood Mononuclear Cells. Evaluation of Intracellular Level of Thiols. Apoptosis.OTIsAtlas of Immunology, Julius M. Cruse and Robert E. Lewis, University of Mississippi Medical Center, Jackson, Catalog no. 9489, January 1998, c. 350 pp., 7x10, ISBN: 0-8493-489-9, $69.95Illustrated Dictionary of Immunology, Julius M. Cruse and Robert E. Lewis, Jr., University of Mississippi, Jackson, Catalog no. 4557, 1995, 352 pp., 8.5x11, ISBN: 0-8493-4557-X, $75.00Handbook of Human Immunology, Mary S. Leffell, Noel R. Rose, and Albert D. Donnenberg, Catalog no. 134, April 1997, 656 pp., 6x9, ISBN: 0-8493-0134-3, $99.95
£78.84
