Hepatology Books

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Book SynopsisProviding anesthesiology for liver surgery and especially liver transplantation is highly complex and requires profound expertise in the physiology and pathophysiology of liver disease. This new edition incorporates the latest information in the field and remains the only available book on the topic. It focuses on the practical aspect of liver anesthesiology and critical care, while providing a comprehensive and in depth summary of the knowledge in this field. Most liver transplant centers now have dedicated teams providing anesthesia care during liver transplantations. In the last years there has been a substantial increase in knowledge and improvement in techniques in anesthesiology and critical care of patients undergoing liver surgery and transplant patients. Liver Anesthesiology and Critical Care Medicine, 2nd Edition includes new chapters on chronic liver failure and hepatic cirrhosis, preoperative risk assessment, evidence in liver anesthesiology, the splanchnic and systemic circulation in liver disease and a special focus on analgesia for liver resection including regional techniques. Written for anesthesiologists and critical care physicians caring for patients undergoing liver surgery and transplantation, this book proves to be an essential companion and review book as the number of liver surgeries with higher complexity continue to increase.Table of ContentsSection I: Physiology, Pathophysiology and Pharmacology of Liver Disease Physiology and anatomy of the liver Chronic liver failure and hepatic cirrhosis The splanchnic and systemic circulation in liver disease Drug metabolism in liver failure Evaluation of liver function and injury Section II: Anesthesiology for Liver Transplantation. History of liver transplantation Recipient and donor selection and transplant logistics: the European perspective Recipient and donor selection and transplant logistics: the US perspective Preoperative risk assessment Surgical techniques of liver transplantation Intra-operative monitoring Anesthetic techniques and practice patterns Caval crossclamping, piggy-bag & veno-venous bypass 14. Hemodynamic manag ement and use of vasopressors 15. Coagulopathy: pathophysiology, evaluation & treatment Massive blood loss and blood transfusion Organ protection & the marginal donor / recipient Pediatric liver transplantation Combined Transplants: Liver / -heart / -kidney / -lung transplantation The patient with a high MELD Acute liver failure The patient with renal failure undergoing liver transplantation The patient with cardiac disease Pulmonary disease & hepatopulmonary syndrome Neurological disease and increased intracranial pressure Section III: Anesthesiology for Liver Surgery. Types of liver surgery and indications Anesthetic management, monitoring, fluids & electrolytes Anesthetic aspects of the living donor hepatectomy Analgesia for l iver resection including regional techniques Complications of liver surgery The patient with liver disease undergoing non-hepatic surgery . Section IV: Critical Care Medicine for Liver transplantation. Routine postoperative care Immunosuppression Acute kidney injury Early graft failure Sepsis and infection Respiratory failure and ARDS Pain management Section V: Critical care Medicine for Liver surgery. The living related liver donor Early complications: Liver failure, bile leak and sepsis

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Book Synopsis

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Book Synopsis

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Book SynopsisTextbook of Pediatric Hematology & Hemato-Oncology is a highly illustrated, comprehensive guide to diseases and cancers of the blood in paediatrics. Fifty chapters by internationally recognised paediatric haematologists and haemato-oncologists are grouped into seven sections, covering physiology, neonatal haematology, red blood cell and white blood cell disorders, bleeding disorders, transfusion medicine, haemato-oncology and other general topics. The haemato-oncology section covers cancers of the blood and includes lymphoblastic leukaemia, myeloid leukaemia (chronic and acute), juvenile myelomonocytic leukaemia, and bone marrow transplantation. The final ‘general’ section features discussion on gene therapy, monoclonal antibodies and biological response modifiers. Each chapter is peer-reviewed, with a list of references ensuring authoritative content, and the book is further enhanced by nearly 200 images and illustrations. Textbook of Pediatric Hematology & Hemato-Oncology is an indispensable resource for paediatricians, practitioners and trainees. Key Points Comprehensive guide to paediatric diseases and cancers of the blood 50 peer reviewed chapters with references 198 images and illustrations Table of ContentsSECTION-1 PHYSIOLOGY 1. Ontogeny of Erythropoiesis 2. Physiology of Blood Coagulation 3. Structure, Function and Physiology of Platelets SECTION-2 NEONATAL HEMATOLOGY 4. Variation in the RBC Parameters in the Newborn 5. Physiological Anemia of Newborn, Anemia of Prematurity and Role of Erythropoietin in the Management 6. Effect of Maternal Iron Status on Placenta, Fetus and Newborn 7. Developmental Aspects of Hemostasis in the Fetus and Newborn 8. Anemia in the Newborn 9. Polycythemia and Hyperviscosity Syndrome 10. Vitamin K Deficiency: Bleeding in Newborns 11. Bleeding Neonate: Approach and Management 12. Approach to Neonatal Thrombocytopenia SECTION-3 RBC and WBC DISORDER 13. Introduction and Classification of Anemias in Children 14. Nutritional Anemia in Infancy, Childhood and Adolescents 15. Megaloblastic Anemia 16. Anemia of Chronic Disease 17. Thalassemia Syndromes 18. Sickle Cell Anemia in Children 19. Antenatal Diagnosis of Hemoglobinopathies 20. Red Cell Membrane Disorders (spherocytosis, elliptocytosis, stomatocytosis) 21. Red Cell Enzymopathy 22. Autoimmune Hemolytic Anemia 23. Paroxysmal Nocturnal Hemoglobinuria 24. Diagnosis and Management of Acquired Aplastic Anemia in Children 25. Inherited Bone Marrow Failure Syndromes 26. Benign Disorders of Neutrophils SECTION-4 BLEEDING DISORDERS 27. Approach to a Bleeding Child 28. Diagnosis and Management of Hemophilia Patients 29. Von Willebrand Disease and the Other Rare Coagulation Disorders 30. Acquired Inhibitors of Coagulation 31. Idiopathic Thrombocytopenic Purpura - Diagnosis and Management 32. Platelet Function Disorders 33. Pediatric Thrombosis 34. Disseminated Intravascular Coagulation in Neonates SECTION-5 TRANSFUSION MEDICINE 35. Blood Components in Pediatric Practice 36. Nucleic Acid Amplification Testing 37. Transfusion Transmitted Infections 38. Noninfectious Hazards of Blood Transfusion SECTION-6 HEMATO-ONCOLOGY 39. Pediatric Acute Lymphoblastic Leukemia 40. Pediatric Acute Myeloid Leukemia 41. Chronic Myeloid Leukemia 42. Juvenile Myelomonocytic Leukemia 43. Pediatric Hodgkin Lymphoma 44. Non-Hodgkin Lymphoma in Children and Adolescents 45. Langerhans Cell Histiocytosis 46. Hemophagocytic Lymphohistiocytosis: Revisited 47. Bone Marrow Transplantation SECTION-7 GENERAL 48. Gene Therapy 49. Monoclonal Antibodies in Pediatric Hematology and Oncology 50. Biological Response Modifiers

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Book SynopsisThis book is a complete and practical guide to the management of gastrointestinal and liver disorders. Each chapter is dedicated to a specific disorder and topics include peptic ulcers, gastric cancer, Hepatitis, irritable bowel syndrome, cirrhosis of the liver, pancreatitis and liver disease. Each disease is explained in depth, covering its pathophysiology, clinical presentation, diagnosis and treatment. The comprehensive text is enhanced by high quality clinical photographs, tables and figures. Key points Comprehensive guide to management of gastrointestinal and liver disorders Presents numerous disorders, their physiology, clinical presentation, diagnosis and treatment Highly illustrated with clinical photographs, tables and figures Invaluable, practical reference for trainees and practising gastroenterologists Table of Contents Chapter 1: Gastroesophageal Reflux Disease Chapter 2: Carcinoma of Esophagus Chapter 3: Peptic Ulcer Disease Chapter 4: Peptic Ulcer Disease in Asia-Pacific Chapter 5: Functional Dyspepsia Chapter 6: Gastric Cancer Chapter 7: Malabsorption Disorders Chapter 8: Abdominal Tuberculosis Chapter 9: Inflammatory Bowel Disease Chapter 10: Irritable Bowel Syndrome Chapter 11: Colorectal Carcinoma Chapter 12: Gastrointestinal Lymphomas Chapter 13: Gastrointestinal Stromal Tumor Chapter 14: Acute Diarrheal Diseases Chapter 15: Liver Immunology Chapter 16: Inborn Errors of Bilirubin Metabolism Chapter 17: Hepatitis A and E Viruses Chapter 18: Hepatitis B Virus Chapter 19: Viral Factors and Host Immune Response to Hepatitis B Virus Chapter 20: Hepatitis C Chapter 21: Emerging and Re-Emerging Factors About Hepatitis Virus Control In Developing Countries Chapter 22: Nonalcoholic Fatty Liver Disease Chapter 23: Alcoholic Liver Disease Chapter 24: Primary Sclerosing Cholangitis Chapter 25: Primary Biliary Cirrhosis Chapter 26: Autoimmune Hepatitis Chapter 27: Amoebic Liver Abscess Chapter 28: Pyogenic Liver Abscess Chapter 29: Hydatid Cyst of Liver Chapter 30: Leptospirosis Chapter 31: Cirrhosis of Liver Chapter 32: Ascites Chapter 34: Hepatocellular Carcinoma Chapter 35: Portal Hypertension: Pathophysiology and Management Chapter 36: Hepatorenal Syndrome Chapter 37: Drug-Induced Liver Injury Chapter 38: Acute Liver Failure Chapter 39: Biliary Atresia Chapter 40: Liver Diseases in Pregnancy Chapter 41: Liver Transplantation Chapter 42: Gallstone Disease Chapter 43: Cholangiocarcinoma Chapter 44: Acute Pancreatitis Chapter 45: Chronic Pancreatitis Chapter 46: Carcinoma Pancreas

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Book SynopsisTextbook of Pediatric Gastroenterology, Hepatology and Nutrition is a comprehensive and up-to-date resource covering disorders of the liver and digestive system. This book is divided into three sections on gastroenterology, nutrition and hepatology respectively, encompassing 37 chapters. The book describes the pathophysiology of a range of paediatric disorders from diseases of the oesophagus and malnutrition, to chronic liver disease, as well as new genetic, metabolic and biochemical tests. Novel therapies are discussed for treatment of diseases such as tyrosinemia and neonatal haemochromtosis, and the hepatology section describes improved treatment for Hepatitis B and C in relation to liver transplantation. New modalities in endoscopy such as endoscopic ultrasound and capsule endoscopy in gastrointestinal disorders are also covered in detail. Enhanced by over 100 images and illustrations, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition is an extensive guide to conditions of the digestive system and liver, which will assist postgraduates, paediatric gastroenterologists and other paediatricians in their practice. Key Points 37 chapters covering a range of disorders of the digestive system and liver Introduces new therapies and treatment modalities 100+ images and illustrations Table of ContentsGastroenterology Developmental Anatomy and Physiology of the Digestive Tract Approach to Common Gastrointestinal Symptoms and Signs Disorders of the Oesophagus Neuro-Gastroenterology and Motility Disorders Disorders of the Stomach and Small Intestine Acute Diarrhoea Chronic and Persistent Diarrhoea Celiac Disease Inflammatory Bowel Disease Disorders of the Pancreas Short Bowel Syndrome Surgical Disorders of Gastrointestinal Tract Nutrition Nutritional Assessment in Health and Disease Food Allergies Malnutrition Enteral Nutrition Parenteral Nutrition Probiotics in GI Disorders Hepatology Anatomy, Development and Physiology of the Hepatobiliary System Approach to Common Liver Symptoms and Signs Interpretation of Liver Function Tests Neonatal Cholestasis Acute Hepatitis Chronic Viral Hepatitis Autoimmune Hepatitis Wilson’s Disease Metabolic Disorders in the Infant Metabolic Disorders in the Older Child Non-Alcoholic Fatty Liver Disease Chronic Liver Disease Surgical Disorders of the Hepatobiliary System Drug Induced Liver Injury Acute Liver Failure Portal Hypertension Liver Transplantation Liver Tumours The Liver in Systemic Illness

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Book SynopsisThis book is a complete guide to the evaluation and interpretation of liver biopsy specimens for clinicians, providing the latest techniques and advances in the field. Beginning with an introduction to the structure and function of the ‘normal’ liver, and discussion on situations requiring biopsy, and types of specimen, the following sections describe pathologic variations of liver diseases, ways to identify the changes, and qualitative and quantitative evaluation. The book covers the full spectrum of disorders and diseases that may occur in the liver and includes chapters dedicated to liver transplant pathology, and paediatric liver disease. Current terminologies, grading and staging systems used in liver biopsy, are discussed in detail. High definition slides and images enhance learning, and each chapter concludes with ‘points to remember’ highlighting the key features of the topic. Key Points Complete guide to evaluation and interpretation of liver biopsy specimens Covers the full spectrum of liver disorders and diseases Includes discussion on terminologies, grading, and staging systems Features high definition slides and images, and key learning points Table of ContentsSection I: Liver Biopsy Normal Liver Important Aspects of Liver Biopsy Approach to Liver Biopsy Special Stains and IHC Acute on Chronic Liver Failure and Clinical Scores Section II: Hepatitic Pathology Acute Hepatitis Chronic Viral Hepatitis Autoimmune Hepatitis Section III: Steatotic Pattern NASH Alcoholic Liver Disease Section IV: Cholestatic Pattern Cholestatic Pathology Billiary Pathology Vanishing Bile Duct Syndrome Overlap Syndromes IgG4 Cholangiopathy Section V: Vascular Pattern NCPF, EHPVO, VOD Section VI: Mixed Pattern DILI-Dr Chaggan Section VII: Specific Pathologies Wilson Disease Hemochromatosis Metabolic Liver Disease Section VIII: Pediatric Liver Diseases Ductal Plate Malformation Congenital Hepatic Fibrosis, Caroli’s Disease Cholestatic Pediatric Diseases - EHBA, NH, PFIC, AATD, CF Section IX: Cirrhosis Cirrhosis Section X: Transplant Pathology Transplant Pathology Section XI: Nodular Lesion Liver Nodular Lesion Liver

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Book SynopsisThis book guides practitioners in the assessment of patients with a liver problem. The emphasis is on the role of macro- and microscopic pathology in elucidating pathogenesis as well as identifying confounding features of image findings that may lead to a more elaborate differential diagnosis. If appropriate, the role of light and electron microscopic examination, along with the role of specific stains and molecular techniques, is illustrated. In addition, the concept of each liver disease is summarized briefly and its up-to-data is provided, and unresolved problems in diagnosis, treatment, and pathogenesis are clearly described.The approach in this book is a practical one with a focus on the evaluation of illustrative cases, simultaneously demonstrating cross-sectional images (ultrasonography, computed tomography, magnetic resonance imaging, and angiography), pathological findings, and peritoneoscopic images. The diagnosis and therapy are summed up in helpful tables, and association of clinical manifestations with image analysis and pathological findings is shown to be important in differential diagnosis and treatment. With the authors comprising internationally renowned experts, this book will serve as a useful source of information for medical students, physicians, internists, hepatologists, gastroenterologists, radiologists, and pathologists worldwide.Table of Contents1.Anatomy and Function.- 2.Laboratory tests in liver diseases.- 3.Acute Hepatitis.- 4.Acute Liver Failure.- 5.Chronic Hepatitis.- 6.Liver Cirrhosis.- 7.Alcoholic Liver Disease and Nonalcoholic Fatty Liver Disease / Nonalcoholic Steatohepatitis.- 8.Drug-induced Liver Injury.- 9.Autoimmune Liver Disease.- 10.Developmental Abnormalities of the Bile Duct & Foregut.- 11.Vascular Disorders in Liver.- 12.Metabolic Disorders in Liver.- 13.Hyperbilirubinemia.- 14.Granulomatous Liver Diseases.- 15.Liver Disorders in Systemic Diseases.- 16.Liver Tumor I: Benign Tumors and Tumor-Like Lesions.- 17.Liver Tumors II: Malignant Tumors of the Liver.- 18.Metastatic Liver Tumors.- 19.Liver pathology in transplantation.- 20.Peritoneal Diseases.

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Book SynopsisThe scope of the book is very broad, covering a wide range of areas in HBV/HDV and HCV research, including both basic and clinical science. The selected topics range from epidemiology, immunology, molecular virology and oncology, to clinical therapy.Chronic Hepatitis B and C consists of 14 chapters, each being a review of a special topic on HBV or HCV. While review articles on a special topic can be found in periodical journals, they tend to be more restricted in presentation. Therefore, this book will provide more in-depth coverage of what are presented as “unpublished results” and “data not shown” in journal articles. Furthermore, several authors in this book do not write review articles regularly. Some authors wrote reviews on a specific topic regularly, but they tried a new topic in this book (e.g., Dr. YF Liaw on “natural course,” Dr. Shih on “virion release,” Dr. Michael Lai on “lymphotropism of HCV,” etc. ⋯). Overall, the book will offer useful information at the cutting age.Sample Chapter(s)Table of ContentsHepatitis B Virus: Natural Course of Chronic Hepatitis B Virus Infection (Y F Liaw & C M Chu); Immune Response and Viral Hepatitis B (D Milich); Epidemiology of Viral Hepatitis B-related Hepatocellular Carcinoma (K A McGlynn et al.); Molecular Biology of HBV-related Hepatocellular Carcinoma (A J Hodgson & B Slagle); Treatment of Chronic Viral Hepatitis B and Drug Resistant Variants (T Nguyen et al.); The Release of HBV Particles (C Shih); Recent Development in Hepatitis Delta Virus (C Sureau); Hepatitis C Virus: Development of an HCV Cell Culture System (T Kato & T Wakita); Innate Immune Defense and Flaviviridae (M Gale Jr & M Diamond); Lymphotropism of Hepatitis C Virus (M Lai & K Machida); Expression and Functions of Hepatitis C Virus F Protein (J Ou); Treatment of Hepatitis C Infection (D-S Chen & C-J Liu); The Complexities of Hepatitis C Virus Entry (J McKeating et al.).

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Book SynopsisInflammation and cancer are two major disorders that cause huge concerns in our society. However, what one may not know is that both diseases are closely associated and, in particular, both occur in the gastrointestinal tract and liver. This book describes the mechanics of how inflammation can progress to cancer in these organs. The authors in this book comprehensively discuss the different biomarkers for early diagnosis, and current therapeutic treatments for these diseases. All of these would allow us to better understand the pathogenesis of both diseases. As such, this book provides comprehensive information concerning the interrelationship between inflammation and cancer in a cohesive manner, and the information derived would benefit not only basic scientists but also clinicians who are working in these fields.Table of ContentsPathogenic Mechanisms of Inflammation and Cancer; Hepatitis; Inflammatory Bowel Disease; Colorectal Cancer; Mediators in Inflammation and Cancer; Interventional Radiology; Tumor Markers.

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