Gynaecology and obstetrics Books

Book SynopsisDesigned for providers of women's healthcare, this manual guides those implementing QI and safety programs with emphasis on obstetrics and gynecology. The book contains case-based elements to improve accessibility and understanding. The editors are involved with global initiatives educating physicians in safety aspects of practice.Table of Contents1. Office safety Ty B. Erickson and Amber D. Masse; 2. Electronic fetal monitoring and patient safety David Miller; 3. Patient safety in the outpatient setting Roger Smith and Mark D. Pearlman; 4. Principles for the safe use of electrosurgery Fidel A. Valea; 5. The obstetric-gynecologic hospitalist Christopher C. Swain and Alan M. Dulit; 6. Transparency and disclosure Sandra Koch; 7. Surgical checklists John Wachtel and Abraham Lichtmacher; 8. What is a high-reliability organization? Joseph C. Gambone and John P. Keats; 9. Powerful tools for quality improvement John P. Keats; 10. Simulation and drills Shad Deering; 11. Rapid response in obstetrics Allison R. Durica and Elizabeth S. McCuin; 12. Regulatory and legal implications Mark S. Defrancesco; 13. Patient safety: a patient's perspective Pamela K. Scarrow; 14. Safety programs in a community hospital – evidence-based medicine meets the realities of private practice Holly S. Puritz; 15. Improving perinatal safety in an integrated healthcare system Hans P. Cassagnol and Harry Mateer; 16. Fatigue and safety Peter A. Schwartz, James W. Saxton and Maggie M. Finkelstein; 17. Just culture in women's health services Michael E. Barfield, Margaret Sturdivant and Karen Frush; 18. Medication safety in obstetrics and gynecology Roseann Richards and Angela Brenner; 19. Improving patient safety through team training Christian M. Pettker and Edmund F. Funai; 20. A systems-based approach to shoulder dystocia safety William A. Grobman; 21. Creating a learning culture: debriefing and root-cause analysis Nancy Chescheir; 22. Safe patient handoffs Diana Behling and Bonnie Dattel; 23. Using clinical scenarios to teach patient safety Dotun Ogunyemi, Bruce B. Ettinger and Steve Rad; 24. Quality and safety in medical education: implementing a curriculum of patient safety and quality improvement in medical education Dotun Ogunyemi.

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Book SynopsisSimulation is becoming an integral part of medical education and has already a well-established role within anaesthesia training, with many examination questions already modelled on simulation scenarios. The clinical diversity and multidisciplinary nature of an obstetric team creates the ideal environment for simulation training. It enables the team to develop their knowledge of clinical emergencies whilst becoming more aware of the importance of human factors. This book is a practical guide to inspire clinical leads to establish simulation within their delivery suite. The book comprises an extensive obstetric scenario library, with each scenario broken down into learning outcomes, a list of staff and equipment needed, specific stages mapped to learning outcomes with appropriate results/investigations and a checklist of ideal actions to enable the post-scenario debrief. Written by consultant obstetric anaesthetists, this book will appeal to medical practitioners interested in facilitaTrade Review'Obstetric Decision-Making and Simulation is a practical guide to inspire and instruct the integration of simulation-based learning into multidisciplinary obstetric department education.' Panagiota Sceales, International Anesthesia Research SocietyTable of ContentsList of Contributors; Foreword; Part I. The Role of Simulation: 1. Setting the scene for simulation-based education Debra Nestel, Kristen Moloney and Simon Hyde; 2. The where of simulation training Al May; 3. Interprofessional in-situ simulation Jonathan Hurst; 4. Debriefing and the debrief Mark Murphy and Annemarie Brown; 5. Fidelity in obstetric simulation Shane O'Sullivan and Owen O'Sullivan; Part II. The Impact of Human Factors in Clinical Practice: 6. Introduction to human factors and ergonomics in obstetric simulation Mark Hellaby; 7. Situational awareness, bias and decision making styles in obstetric simulation Ian Parkinson and Andrew F. Smith; 8. Team-working, communication and use of communication aids and checklists in an emergency Simon Mercer; Part III. Clinical Scenarios: 9. Introduction to the scenarios Kirsty Maclennan; Scenario Section 1: Obstetric; 10. Uterine inversion Samantha Bonner; 11. Shoulder dystocia following forceps delivery for fetal bradycardia Samantha Cox and Samiksha Patel; 12. Umbilical cord prolapse Michelle McIntosh; 13. Minimising decision to delivery interval (DDI) in a category 1 caesarean section – pre-theatre phase Cliff Shelton and Sophie Bishop; Scenario Section 2: Maternal collapse; 14. Amniotic fluid embolism Kim Macleod and Yara Mohammed; 15. Anaphylaxis in labour Andrew Parkes and Shuayb Elkhalifa; 16. Acute pulmonary embolism in pregnancy Louise Simcox and David Simcox; Scenario Section 3: Haemorrhage; 17. Antepartum haemorrhage and perimortem caesarean section Kenneth Ma; 18. Vasa praevia Shimma Rehman; 19. Postpartum haemorrhage Pavan Kochhar and Stuart Knowles; Scenario Section 4: Sepsis; 20. Group A streptococcal puerperal sepsis Laura Coleman and Melissa Whitworth; 21. Pneumonia and respiratory failure in a pregnant woman James Hanison and Dougal Atkinson; Scenario Section 5: Hypertensive disorders of pregnancy; 22. Eclampsia Stephanie Worton, Emma Shawkat and Jenny Myers; 23. HELLP syndrome with fetal compromise requiring an emergency GA caesarean section Emma Shawkat, Stephanie Worton and Jenny Myers; 24. Microangiopathic haemolytic anaemia (MAHA) in pregnancy presenting in A&E Louise Simcox and Jo Gillham; Scenario Section 6: Cardiac; 25. Chest pain in a pregnant patient Shahid Karim and Sarah Vause; 26. Peripartum cardiomyopathy Omar Asghar and Sarah Vause; 27. Complete heart block in a pregnant patient Anita Macnab and Kirsty Maclennan; 28. Cardioversion in a pregnant patient with corrected tetralogy of fallot Kailash Bhatia; Scenario Section 7: General anaesthesia; 29. General anaesthesia and failed intubation in a category 1 caesarean section Richard McGuire and Sharon Smith; Scenario Section 8: Neuraxial analgesia; 30. Subdural block in labour Kathryn A. Wood and Lorna A. Howie; 31. Total spinal anaesthesia in labour K. E. Gott and Sophie Kimber-Craig; 32. Severe local anaesthetic toxicity in labour Charlotte Ash and Suna Monaghan; Scenario Section 9: Non-neuraxial analgesia; 33. Respiratory arrest in a woman using remifentanil PCA for labour Michael McGinlay and Susan Davies; Scenario Section 10: Endocrine; 34. Diabetic ketoacidosis in pregnancy Samantha Bonner and Jonathan Schofield; Scenario Section 11: Neurological; 35. Subarachnoid haemorrhage in the post partum patient Craig Carroll and Daniel Holsgrove; Scenario Section 12: Trauma; 36. Obstetric trauma John Butler; Scenario Section 13: Neonatal; 37. Newborn life support (preterm delivery) in obstetric anaesthesia Jonathan Hurst; Index.

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Book SynopsisUterine fibroids are very common in women of reproductive age and are mostly benign. However, they are often a cause of abnormal bleeding and, in severe cases, can cause infertility. This comprehensive guide reviews the clinical management of uterine fibroids, with a particular focus on practical surgical techniques. Engage with topics such as the anatomy of the pelvis, key theatre equipment and surgical treatments including hysteroscopic and laparoscopic techniques. Features also include debates around morcellation, and less invasive treatments such as uterine artery embolisation are also covered. An online video library of surgical procedures reinforces the practical techniques taught in the book and detailed colour images supplement the book''s thorough coverage of fibroid management. This makes Modern Management of Uterine Fibroids an essential resource for practicing gynaecologists and IVF specialists, as well as students.Trade Review'I would recommend this book to any general obstetricians/gynecologists looking to expand the treatment options they provide to their patients.' Jessica K. Shields, Doody's NoteTable of ContentsForeword Ian Cooke; 1. Pathophysiology of uterine fibroids Mohamed Otify and Hilary Critchley; 2. Evaluation of uterine fibroids using two-dimensional and three-dimensional ultrasonography Sotirios Saravelos; 3. Ulipristal and other medical treatments for the management of uterine fibroids Mohamed Ali, Zunir Chaudhry and Ayman Al-Hendy; 4. The role of MRI imaging in the management of fibroids Lisa Shannon and Shahram Abdi; 5. Fibroids and fertility Tulay Karasu and Mostafa Metwally; 6. Fibroids and reproduction Elizabeth Pritts; 7. Open myomectomy Tin-Chiu Li and Jacqueline Chung; 8. Instrumentation for laparoscopic and robotic myomectomy Ahmed El-Minawi; 9. Principles and techniques of laparoscopic myomectomy Ephia Yasmin and Ertan Saridogan; 10. Uterine fibroids: the morcellation debate Jimmy Alvarez and Charles Miller; 11. Total laparoscopic hysterectomy for fibroid uterus Alpha Gebeh and Mostafa Metwally; 12. Hysteroscopic resection of submucosal fibroids Rudi Campo and Cristine Di Cesare; 13. Intramural myoma and fertility Dan Yu, Tin-Chiu Li and Enlan Xia; 14. Outpatient myomectomy Mary Connor; 15. Vaginal hysterectomy with fibroids Swati Jha; 16. Leiomyosarcoma: implications for the treatment of fibroids Elizabeth Pritts; 17. MRI-guided ultrasound lysis of fibroids Jessica Gelman and Charles Miller; 18. Uterine fibroid embolization for the management of uterine fibroids Mark Regi, Krit Dwivedi and Trevor Cleveland; 19. Uterine fibroids in postmenopausal women Mohamed Ali, Zunir Chaydhry and Ayman AlHendy; Index.

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Book SynopsisFor over forty years, assisted reproductive technology (ART) has helped millions of patients around the world to overcome infertility. Careful monitoring of ART treatments and their outcomes is vital to maintain the remarkable pace of change in science and technology, whilst minimizing potential risks to infertility patients, and their children. Written by forty-five authors from twenty countries around the world, this book represents a global effort to document the history of assisted reproductive technology surveillance, and its dynamic challenges across the world. Comprehensive in its approach, the text details best practices in collecting and using ART surveillance data to monitor treatment effectiveness and safety, improve quality of care, develop health policy, and provide accurate information to infertility patients, worldwide.Table of ContentsList of contributors; Foreword; Part I. Introduction to Assisted Reproductive Technology Surveillance: 1. Infertility and assisted reproductive technology Sheree L. Boulet, Anjani Chandra, Aaron Rosen and Alan DeCherney; 2. Importance and history of assisted reproductive technology surveillance Jacques de Mouzon, Paul Lancaster and Anders Nyboe Andersen; Part II. General Principles of Assisted Reproductive Technology Surveillance: 3. Assisted reproductive technology surveillance: who, what, when, and how? Sara Crawford, Dmitry M. Kissin and Georgina Chambers; 4. Future directions for assisted reproductive technology surveillance and monitoring novel technology Christian De Geyter and Eli Y. Adashi; Part III. Using Assisted Reproductive Technology Surveillance Data: 5. Reporting assisted reproductive technology success rates Georgina Chambers, Kevin Doody and Sara Crawford; 6. Using assisted reproductive technology surveillance data in clinical research Valerie L. Baker, Sheree L. Boulet and Anja Bisgaard Pinborg; 7. Monitoring assisted reproductive technology safety and biovigilance Luca Gianaroli, Anna Pia Ferraretti and Borut Kovacic; 8. Quality assurance of assisted reproductive technology practice: using data to improve clinical care Kevin Doody, Carlos Calhaz-Jorge and Jesper Smeenk; 9. Monitoring long-term outcomes of assisted reproductive technology: linking surveillance data with other datasets Barbara Luke, Sheree L. Boulet and Anna-Karina Aaris Henningsen; 10. Use of assisted reproductive technology surveillance by infertility patients Sandra K. Dill, Edgar Mocanu and Petra Thorn; Part IV. Global Variations in Assisted Reproductive Technology Surveillance: 11. Global assisted reproductive technology surveillance: data from the international committee monitoring ART (ICMART) G. David Adamson; 12. Global variations in assisted reproductive technology policy: data from the international federation of fertility societies (IFFS) Steven J. Ory and Kathleen Miller; 13. ART surveillance in Africa Silke Dyer, Paversan Archary and G. David Adamson; 14. ART surveillance in Asia Osamu Ishihara, Manish Banker and Bai Fu; 15. ART surveillance in Australia and New Zealand Georgina Chambers, Paul Lancaster and Peter Illingworth; 16. ART surveillance in Europe Christian de Geyter, Markus S. Kupka and Carlos Calhaz-Jorge; 17. ART surveillance in the Middle East Johnny Awwad, Dalia Khalife and Ragaa Mansour; 18. ART surveillance in North America James Patrick Toner, Andrea Lanes and Dmitry M. Kissin; 19. ART surveillance in Latin America Fernando Zegers-Hochschild, Javier A. Crosby and Juan Enrique Schwarze; Part V. Surveillance of Non-ART Fertility Treatments: 20. The role of non-IVF fertility treatments in the management of infertility Christine Wyns, Diane de Neubourg and Eli Y. Adashi; 21. Non-ART surveillance Markus S. Kupka and Anja Bisgaard Pinborg; Appendix A. Assisted reproductive technology surveillance system variables and definitions; Appendix B. International glossary on infertility and fertility care; Appendix C. ICMART data collection form; Index.

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Book SynopsisThe purpose of sexual and reproductive healthcare should be the enhancement of personal relationships and a healthy sex life and not merely counselling and care related to procreation or sexually transmitted infections. Providing practical and evidence-based guidance, this handbook follows the curriculum of the joint EBCOG and ESCRH Certificate and Diploma Examination in Sexual and Reproductive Health. Short, clearly structured text focuses on the essential knowledge of each topic, allowing readers to quickly access key information. Written by trusted experts in the field, topics covered include contraception, infertility and sexual dysfunction, sexual violence and STIs. The text provides advice and practical tips for how to practice patient-centred counselling and shared decision-making. Improving the relationship between the patient and healthcare-provider leads to increased trust, adherence of advice and more satisfactory treatment for the patient.Table of ContentsSection 1. Scientific Basis of Contraception and Family Planning: 1. Basic physiology of menstrual cycle and ovulation; 2. Physiological basis of female contraception; 3. Basic physiology of spermatogenesis; 4. Mechanisms of male contraception; 5. contraceptive counseling: An interactive approach; Section 2. Methods of Contraception: 6. Combined hormonal contraceptives; 7. Progestogen-only contraceptives; 8. Depot hormonal contraceptive devices; 9. Non-hormonal intra-uterine device; 10. Barrier methods: Male and female; 11. Fertility awareness-based methods; 12. Female sterilization; 13. Male sterilization; 14. Male hormonal contraception; 15. Emergency contraception; Section 3 Contraception and Medical Conditions: 16. Contraception for cancer patients; 17. Benign breast disease, and benign uterine and ovarian; 18. Cardiovascular disease and contraception; 19. Respiratory diseases; 20. Renal diseases; 21. Contraception for obese women; 22. Contraception and HIV; 23. Neurological and psychiatric disorders; 24. Contraception for women with immunosuppressive conditions; 25. Previous organ transplant; 26. Previous bariatric surgery; 27. Systemic lupus erythematosus; 28. Contraception for disabled people; 29. Diabetes (Type 1 and 2) and Gestational Diabetes Mellitus; 30. Thyroid dysfunction; 31. Polycystic ovarian disease; 32. Liver disease; 33. Inflammatory bowel disease; 34. Inherited Blood Disorders (Sickle Cell Disease, Thalassaemia, etc); 35. Contraception for LGBT; 36. Contraception for women with special needs: Life cycle approach to contraception and sexual and reproductive health care; 37. Contraception and drug interaction; Section 4. Subfertility: 38. Male subfertility; 39. Female subfertility; 40. Fertility options for LGBT couples; 41. Pre-pregnancy care; Section 5. Termination of Pregnancy: 42. Medical method for termination of Pregnancy; 43. Surgical methods for termination of pregnancy; 44. Practical approaches to termination of pregnancy at different gestational ages; Section 6. Sexually Transmitted Diseases and Other Vulvovaginal and Urogenital Infections: 45. Vulvovaginal candidiasis; 46. Bacterial vaginosis; 47. Anogenital warts; 48. Trichomonas vaginalis; 49. Anogenital herpes; 50. Chlamydia Trachomatis Infection; 51. Syphilis; 52. Gonorrhoea; 53. Hepatitis; 54. HIV; 55. Mycoplasma genitalium; 56. Molluscum Contagiosum; 57. Acute and chronic pelvic inflammatory disease; 58. Sexually Transmitted Infection, Pelvic Inflammatory Disease and Contraceptive Options; 59. Contact Tracing; 60. Sexually transmitted infections during pregnancy and postpartum; 61. Sexually transmitted infections and complications in newborns; 62. Recurrent vulvovaginal infections (vulvovaginitis); Section 7. Sexual Health: 63. Sexual counseling and basic care for sexual dysfunction; 64. Sexual health and sexual dysfunctions; 65. Sexual violence against women; Section 8. Cervical Cancer Screening: Section 9. Standards of Care for Sexual and Reproductive Healthcare Services; Index.

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Book SynopsisThis succinct, evidence-based book delivers everything you need to provide safe, effective care to pregnant women in subacute and emergency situationsA quick-reference guide designed for on-the-spot clinical guidance, Obstetric Anesthesia: Quick References & Practical Guides fills a gap in the current literature by distilling the information of a comprehensive textbook into a quick review and provides standard instructions that can be integrated into everyday practice. You'll find a collection of common and uncommon clinical challenges with up-to-date obstetric anesthesia practices that serve both experienced and novice clinicians.Chapters include a brief review of the topic, clinical pearls, bullet points and tables highlighting key information, references for the latest scientific information and primary literature, as well as guides, protocols, or standard operating procedures for immediate application, all based on the BIDMC Department of Anesthesiaâs

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Book SynopsisMost women initially discuss health-related matters with a medical practitioner in a primary care setting, whether they have specific concerns or are seeking advice and guidance. This practical and comprehensive guide will help primary care practitioners to deliver holistic women''s health care to patients throughout different life stages. Contraceptive choices, infertility, pregnancy, and menopause are covered, along with specific diseases such as ovarian cysts, breast conditions, and ovarian cancer. All of the authors are GPs, consultants and nurses with experience of the requirements for healthcare delivery in the primary care setting. Each chapter is written in a practical style, including a list of key points and using cases to illustrate the application of the content. This will be invaluable reading for GPs, doctors in training roles, and nurses with an interest in women''s health. It will be particularly useful for candidates preparing for the DRCOG or MRCGP examinations.Trade Review'I welcome this text to further support the development of more women's healthcare being delivered in community and primary care settings. All the authors are experts in the field and are able to write well for those working in out-of-hospital settings.' Chris Wilkinson, President of The Faculty of Sexual and Reproductive Healthcare'… an easy-to-read, very open format, so it has a welcoming, accessible feel about it. You can easily read a chapter over a cup of coffee … Women's Health in Primary Care takes a … practical 'how do you approach this consultation' perspective, with case scenarios and key point boxes, rather than the 'this is everything a thinking GP should know about this topic' position … This is a book that needs to be in every surgery, for that quiet moment, if you ever get one, to dip into for 5–10 mins to refresh and update your ideas about women's health.' Sally Hope, Pulse (www.pulsetoday.co.uk)Table of ContentsList of contributors; Foreword; Preface; 1. The physiology of the menstrual cycle and its impact on menstrual cycle disorders: practical implications for primary care Paula Briggs; 2. Management of children and adolescents with gynaecological problems in primary care Jane Dickson; 3. Contraceptive choices in primary care Joanna Speedie and Diana Mansour; 4. Managing contraception problems in primary care Fiona Sizmur; 5. Management of vaginal discharge in primary care Catherine Armitage; 6. Sexually transmitted infections managed in primary care Richard Ma; 7. Cervical pathology in primary care Christine Corrin; 8. Management of patients with psychosexual problems in primary care Alison Vaughan; 9. Infertility management in primary care Clare Searle; 10. Ectopic pregnancy from a primary care perspective Jacqui Tuckey and Chantal Simonis; 11. Management of miscarriage in primary care Sally Kidsley and Najia Aziz; 12. Pregnancy related issues relevant for primary care Jenny Blackman; 13. Postnatal care in primary care Judy Shakespeare; 14. Polycystic ovary syndrome: management of a long-term condition in primary care Anne Connolly and Virginia Beckett; 15. Management of premature menopause in primary care Henny Lukman, Amanda Hillard and Timothy Hillard; 16. Premenstrual disorders PMD - a practical approach in primary care Carolyn Sadler; 17. Non-menstrual vaginal bleeding management in primary care Clare Spencer; 18. Management of the patient with suspected endometriosis in primary care Keith Louden; 19. Management of the patient with heavy menstrual bleeding in primary care Helen Barnes; 20. Management of the patient with continence problems in primary care Victoria Corkhill; 21. Managing cystitis in primary care Tim Sayer; 22. The management of ovarian cysts in primary care Sally Louden; 23. Managing menopause in primary care Sarah Gray; 24. Vulval dermatoses in primary care Susan Towers and Kate London; 25. Management of the patient with pelvic organ prolapse in primary care Christian Phillips and Charlotte Hutchings; 26. Ovarian cancer - improving outcomes: a primary care perspective Ken S. Metcalf; 27. The management of endometrial hyperplasia and carcinoma in primary care Dileep Wijeratne and Sian Jones; 28. The management of fibroids in primary care Elizabeth Burt and Ertan Saridogan; 29. Osteoperosis and fracture prevention in primary care Pam Brown; 30. Management of the patient with benign and malignant breast conditions in primary care Jo Marsden and Robert Reichert; Index.

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Book SynopsisReproductive aging is a natural and universal process. Women frequently overestimate the age at which a significant decline in fertility occurs as well as overestimate the success of assisted reproductive technologies to circumvent age-related infertility. Yet there is much that modern medicine can do to improve conception rates in women who delay childbearing and to manage subsequent pregnancies. This book offers guidance on winning strategies for maximizing the live-birth rate and limiting the risk for women trying to conceive later in life. It is intended to assist in navigating this challenging journey and lead to peace of mind that women have been seen, heard, and treated as individuals in the process.Written by leading experts addressing medical options of applying advanced reproductive technologies, psychological, nutritional, lifestyle, systematic approaches to optimizing fertility care for the most challenging demographic of women in a practical, clinically orientated, and mosTrade Review'This is a much-needed book for physicians and fellows working with the infertile patient over 40. It offers both a factual guide and review of the up-to-date literature on ART and pregnancy management of women over 40, which is a group that will only continue to grow as a part of our infertility practices.' Sarah Capelouto, Doody's ReviewsTable of ContentsIntroduction Dimitrios S. Nikolaou and David B. Seifer; Part I. Demographic Trends:1. Is 40 the new 30? Increasing reproductive intentions and fertility rates beyond age 40 Éva Beaujouan and Tomáš Sobotka; Part II. The Biological Basis of Female Reproductive Aging: What Happens To The Ovaries And The Uterus As They Age?: 2. The biological basis of female reproductive aging: What happens to the ovaries and uterus as they age? Jacquelyn Shaw, Jennifer K. Blakemore, David L. Keefe; Part III. Lifestyle, Environment and Optimizing Reproduction in the 40s: 3. What lifestyle adjustments can maximize the chance of a natural conception and healthy pregnancy in women over 40? Alexandra Kermack; Part IV. Re-Thinking and Re-Defining “Family Planning” For The 21st Century: 4. Diagnostic testing of reproductive aging David B. Seifer and Tanya Glenn; 5. Fertility preservation for 'Social' reasons Tim Bracewell-Milnes and Dimitrios Nikolaou; Part V. Optimal Deployment of Art Beyond 40: 6. When to use art beyond 40, how often, how many attempts, when to stop Steven D. Spandorfer and Pietro Bartoletto; 7. Optimal IVF protocols for women over 40 and low functional ovarian reserve David H. Barad and Norbert Gleicher; 8. Fertility counselling beyond 40 Amir Mor and David B. Seifer; 9. Support systems and patient experience architecture for fertility care of women over 40 in the 2020s Dimitrios S. Nikolaou and David B. Seifer; Part VI. Obstetric Management Beyond 40: 10. The optimal management of first-trimester pregnancy beyond 40 Beth Cartwright and Aditi Naik; 11. Optimal management of pregnancy beyond 12 weeks, labour and the puerperium for woman over 40 Shane Duffy, Pritha Dasmahapatra; Part VII. The Children of Older Parents: 12. What do we know about the children of women over 40 and what can older mothers do to optimize their children's development? Vickie Schafer and Winifred Mak; Part VIII. What Are Realistic Alternatives to Conceiving With Autologous Eggs?: 13. Practical egg donation in women over 40 James P Toner and Lauren Rouleau; Part IX. New Technologies: 14. Is it likely that reproductive aging could be delayed or reversed using advanced technologies in the future? Paula Amato and Dimitrios Nikolaou; Part X. Ethics: 15. Ethical issues in the use of assisted reproductive technology in women over age 40 Nicole Yoder and Gwendolyn P. Quinn; Final thoughts David B. Seifer and Dimitrios S. Nikolaou; Index.

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Book SynopsisThis book introduces readers to the fascinating interaction of specialized gamete cells, forming the early embryo and a blueprint of new life. Readers will gain a thorough understanding of the complex physiological events and mechanical processes - such as ionic regulation, metabolism and intracellular signalling - to decipher cause and effect in fertilization. Wide-ranging in its approach, this book describes fertilization as a highly conserved mechanism throughout the animal kingdom, taking case studies from echinoderms, ascidians, amphibians and mammals through to other phyla. An excellent companion to undergraduate and postgraduate students of medicine, veterinary and biological sciences, this text provides an underpinning of the mechanisms of fertilization that inform assisted reproduction practice and research in medicine and agriculture. It explores the detailed phases before fertilization: the oocyte as a quiescent cell, attracting its partner gamete, followed by a cascade of pTable of ContentsPreface; 1. Introduction; 2. Producing gametes; 3. The players, sperm and oocytes; 4. Sperm-oocyte interaction; 5. Oocyte activation; 6. The dynamics of fertilization; 7. Transformation of the zygote in to the early embryo; 8. Basic biology concepts; References; Index.

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Book SynopsisChallenge your knowledge of ultrasound to address sexual health abnormalities and early pregnancy issues, alongside identifying, classifying and managing a wide range of gynaecological conditions, with this essential manual. Authored by experts in reproductive health, this bespoke guide delivers practitioners of all levels with a broad scope of sexual and reproductive disorders, as captured by ultrasound. Presenting operational issues and suggested training, this textbook ensures high-quality care in gynaecology, sexual and reproductive health and pregnancy advisory services. For use in a traditional hospital setting through to more remote locations, this guide provides an invaluable toolkit for trainees, sonographers, nurses and clinicians worldwide. Offering clear clinical ultrasound images and extensive case studies with a focus on pregnancy advisory services, this adaptable textbook provides reliable support for those who are in contact with common, rare and understudied reproductiTable of ContentsForeword Diana Mansour; 1. A short history of ultrasound in gynaecology Pat Lewis; 2. Use of the ultrasound system Julie-Michelle Bridson; 3. Communication skills in ultrasound assessment Karen Easton; 4. Ultrasound of pelvic anatomy scanning techniques and 'normal' findings Mary Pillai and Julie-Michelle Bridson; 5. Contrast sonohysterography Mary Pillai; 6. Ultrasound of abnormal pelvic anatomy – benign pathology Mary Pillai; 7. Pregnancy ultrasound for SRH work Mary Pillai; 8. Ultrasound assessment of a potential ectopic pregnancy Karen Easton; 9. Ultrasound imaging of progestogen only subdermal contraceptive implants Paul O'Brien; 10. Ultrasound imaging in relation to intrauterine contraception Zara Haider; 11. The role of ultrasound scanning in the investigation and management of subfertility Paula Briggs and Gab Kovacs; 12. Polycystic ovaries, polycystic ovary syndrome and the role of ultrasound in relation to this condition Paula Briggs and Gab Kovacs; 13. Ultrasound imaging of women with abnormal uterine bleeding Jane Dickson; 14. The use of ultrasound in the perimenopausal patient Steven R. Goldstein; 15. Recognition of possible gynaecological cancer Kathryn Hillaby; 16. Quality in SRH ultrasound service provision Julie-Michelle Bridson; 17. Annotation, archiving, reporting and audit Julie-Michelle Bridson; Glossary of abbreviations and terms; Index.

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Book SynopsisThis comprehensive question-and-answer resource covers all aspects of the curriculum for the Part 2 MRCOG examination. Candidates are given the opportunity to practise the Single Best Answer question style, to cover the content they will encounter in the examination and to assess their knowledge. As consultants actively engaged in the writing of the Part 2 Single Best Answers, the authors and editor have provided directly applicable questions. Candidates to review the syllabus in an organised, systematic manner, with comprehensive explanations for each answer. This title also includes new sections on ethics, training, audit and clinical governance. Mock exams are also available online to familiarise candidates with the real-life examination. The detailed answers, evidence and comprehensive list of references offer an excellent training and reading source for all candidates preparing for the Part 2 MRCOG examination.Table of Contents1. Early pregnancy; 2. Second and third trimester pregnancy; 3. Aneuploidy and anomaly screening; 4. Labour ward management; 5. Obstetric emergencies Ahmed Elbohoty; 6. Obstetric medicine Amy Shacaluga; 7. Saving mothers lives Roshni R. Patel; 8. Infections in pregnancy; 9. Substance abuse and domestic abuse Tamara Kubba; 10. Teenage pregnancy Ahmed Khalil; 11. Contraception; 12. Paediatric and adolescent gynaecology; 13. Genital infections and pelvic inflammatory disease Ahmed Khalil; 14. Minimal access gynaecological surgery Nahed Shaltot; 15. Gynaecological oncology; 16. Menstruation Radwa Mansour; 17. Pelvic pathology Akanksha Sood; 18. Urogynaecology; 19. Conception and assisted reproduction Magdy El-Sheikh; 20. Medical statistics; 21. Professional dilemmas, consent and good medical practice Irene Gafson; 22. Ethics Wafaa Basta; 23. Breast disorders Youssef Abo Elwan; 24. Neonatology; 25. Operative gynaecology and surgical complications; 26. Training and clinical governance in obstetrics and gynaecology Bismeen Jadoon.

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Book SynopsisProfessional development skills encompass non-clinical attributes that contribute towards career development, research and high-quality clinical practice. Professional bodies such as the Royal College of Obstetrics and Gynaecology (RCOG) are placing increasing importance on these skills and they now form part of the RCOG core curriculum, making these skills essential requirements for all junior doctors and newly appointed consultants in today''s health service. This book is an in-depth review of professional development skills, illustrated by case-histories from obstetrics and gynaecology. Issues related to human factors - such as communication, situational awareness, decision-making and team-working - will form the basis of the book. Candidates sitting the Membership of the Royal College of Obstetrics and Gynaecology (MRCOG) examination will gain a better understanding of the principles of professionalism and clinical governance within the specialty. This book is also a useful tool foTable of ContentsPreface; List of contributors; 1. Teaching and facilitating learning in obstetrics and gynaecology Veena Rodrigues; 2. Supporting professional development: assessment and appraisal in obstetrics and gynaecology Jane MacDougall; 3. Research methodology and governance in obstetrics and gynaecology Ioannis E. Messinis, Christina I. Messini, George Anifandis and Alexandros Daponte; 4. Information technology in daily practice in obstetrics and gynaecology Edward Prosser-Snelling and Edward Morris; 5. Clinical governance in obstetrics and gynaecology Vikram Sinai Talaulikar and Sir Sabaratnam Arulkumaran; 6. Clinical standards in obstetrics and gynaecology Tahir Mahmood and Mohamed A. Otify; 7. Revalidation in obstetrics and gynaecology Sharleen Hapuarachi and Catherine E. Aiken; 8. The doctor as an educator Gemma V. Robinson, Catherine E. Aiken and Jeremy C. Brockelsby; 9. Clinical audit in obstetrics and gynaecology Mairead Black; 10. Clinical risk management in obstetrics and gynaecology Sonia Barnfield and Anna Denereaz; 11. Ethics and legal issues in obstetrics and gynaecology Leroy C. Edozien; 12. Clinical leadership and service delivery in obstetrics and gynaecology Jonathan Frost and Timothy Hillard; 13. Human factors in maternity care Rebecca Crowley, Timothy J. Draycott, Rachel Greenwood, Christy Burden and Cathy Winter; Index.

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Book SynopsisThis book offers a valuable mine of clinical information for health professionals and researchers. It gives an overview of the critical role played by Inositols in the therapeutic approach to common obstetrics and gynecological disorders. Inositols are a family of simple carbohydrates naturally found in several foods and human cells. There are potentially nine stereoisomers of Inositols, among them being myo-inositol (MI) and, to a lesser extent, D-chiro-inositol (DCI). These are the most important isoforms for the physiological processes in humans. They exert different actions in the control of glucose homeostasis: MI regulates the activation of glucose transporters and glucose utilization, while DCI modulates the glycogen synthesis. Once incorporated into phosphoglycans, they act as second messengers involved in the signaling transduction cascade of insulin. The metabolism of Inositols is dysregulated in patients with Polycystic Ovary Syndrome (PCOS), highlighting the crucial link between insulin resistance and inositol deficiency in PCOS patients. Therefore, several pre-clinical and clinical studies have been carried out to evaluate their therapeutic usefulness in pathologies where there is an imbalance in MI and DCI levels (from PCOS and gestational diabetes mellitus to infertility). The clinical evidence has demonstrated that MI can be considered widely safe and well tolerated, giving prominence to this versatile molecule. In several trials, the beneficial effect of MI in improving the metabolic and endocrine profile of women with PCOS has been highlighted extensively. Further analyses have shown that the physiological MI:DCI ratio (40:1) is the optimal approach for improving oocyte follicular development and oocyte maturation as well as ovary stimulation and pregnancy outcomes in in vitro fertilization (IVF) procedures. Furthermore, the reader is introduced to a broader area encompassing the Inositols scenery from the history to Inositols nutritional importance, the therapeutic use in preeclampsia, gynecologic oncology, fetal programming as well as their resistance and substance interaction. All these interesting topics will be discussed and deepened in the present book, giving the opportunity to explore in detail every aspect of this effective molecule, bringing the instructions from this guide to everyday practice.

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Book SynopsisUterine myomas are the most common form of benign uterine tumors, occurring in 50-60% of women. Clinically, they are mostly asymptomatic, often incidentally found on pelvic examination or by routine gynecological ultrasonographic evaluation; otherwise, in 30-40% of cases, they cause a large variety of symptoms, depending on their location and size. Currently, the therapeutic options for myomas are medical, radiological, and surgical. The aim of this book is to summarize the evidence regarding epidemiology, pathogenesis, clinical presentation, diagnosis and management of uterine myomas.Table of ContentsFor more information, please visit our website at:https://novapublishers.com/shop/uterine-fibroids-epidemiology-symptoms-and-management/

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Book SynopsisPelvic inflammatory disease (PID) is an entity whose diagnosis is not always easy. The PID comprises a wide range of clinical forms ranging from banal to severe disease processes that compromise the life of the patient. The etiologic diagnosis is not always possible, because the germs responsible cannot always be detected by the usual culture medium, which is why the use of molecular biology techniques is required. The classical definition of PID is a secondary infection of the female genital tract, due to infection of a sexually transmitted disease like Chlamydia trachomatis, or Neisseria gonorrhea. This notion is being displaced by the concept of PID as a secondary infection by a germ from the altered vaginal flora. The interpretation of complementary tests is difficult because severe cases can present with normal analytical profiles, and an absence of findings on imaging tests. Usually, when an image of pelvic abscess is observed, it usually indicates a failure of medical treatments; however, it is possible to perform a step prior to surgical treatment by ultrasound-guided puncture of the abscess. The use of laparoscopy in the PID is very important for both diagnosis and treatment when there is a failure of drug therapy. An early approach to the disease is essential to prevent damage in the female genital tract that will compromise the fertility of the patient in the future.

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Book SynopsisThis book discusses obstetrics and gynecology case reports from several rare cases to challenging cases with well-detailed explanation every step of its practical treatment. The management of obstetrics and gynecology cases raise different strategies to address several clinical problems. This book provides strategies on how to handle cases with up-to-date information. Therefore, this case report is very useful for medical students, midwives, general doctors, obstetrician-gynecologist and other health professional. It is well-written from the best practitioner and researchers. This case report shall be useful and insightful in handling patients in daily practice as well. The Obstetrics and Gynecology Case Report consists of 26 reports from a variety of patient cases. There are cases of abortion, preterm premature rupture of the membranes, mothers with systemic infection, preterm birth and low birth weight, child sexual abuse, intrauterine fetal death, tuberculosis in pregnancy, cesarean scar in pregnancy, autoimmune hepatitis during pregnancy, polycystic ovary syndrome, endometrial cancer, endometriosis, disorder of sex development, congenital adrenal hyperplasia, fallopian tube cancer, cervical fibroids, last stage of cervical cancer, malignant melanoma of the vagina, extramammary Paget's disease, and in vitro fertilization case. Those cases explore comprehensive solutions using the multidisciplinary approach from biological, psychological, and social aspects of its cases to manage the patients optimally.Table of ContentsPrefaceA Case of Illegal Pregnancy Termination by an Adolescent GirlBiophysicosocial impacts on Preterm Premature of Ruptured Membrane (PPROM) Below 20 WeeksUnintended Pregnancy in Unmarried Women in IndonesiaSafe and Clean DeliveryBiopsychosocial Impacts in Pregnancy among Victims of IncestHolistic and Multidisciplinary Approaches in a Grandemultiparous Woman with TuberculosisSuccessful Conservative Management of a High-Level -HCG Cesarean PregnancyHolistic Management in Obstetric CasesAutoimmune Hepatitis during Pregnancy: Optimal Management for Delivering at TermAlert in Contraceptive Implant Failure: A Case ReportEmbryo Quality after Intra-Cytoplasmic Sperm Injection Involving Sperm Associated with Azoospermia and Aged Oocytes: A Case ReportRole of Preimplantation Genetic Screening in a Case of Recurrent in Vitro Fertilization FailureBio-Psychosocial Aspects of Infertility: Illustrative Case of Recurrent Failure with Assisted Reproductive TechnologiesInfertility Due to Polycystic Ovary SyndromeAggressive Management of Low-Risk Endometrial Cancer in Infertile Patients of Low Socioeconomic StatusBiopsychosocial Approach in a Woman with Chronic Pelvic Pain, Abnormal Uterine Bleeding, and Primary Subfertility Due to EndometriosisMultidisciplinary Approach to Gender Reassignment Surgery in a DSD 46XX Patient with Delayed Diagnosis of Congenital Adrenal Hyperplasia: A Case ReportOne of the Most Rare Gynecologic Malignancies: A Serial Case Report on Fallopian Tube CancerFallopian Tube Carcinoma: A Case Report on Its Histopathological AspectApproach and Management of Cervical Fibroids: A Case ReportRare Case of Incisional Site Abdominal Wall Metastasis from Uterine Cervical Cancer Recurrence Disease: A Case Report and Literature ReviewHow to Diagnose and Manage Malignant Melanoma of the Vagina, an Aggressive Melanoma: An Evidence-Based Case Report and ReviewAcquired Labial Fusion Mimicking Congenital Urogenital Sinus Anomaly: A Case ReportExtramammary Pagets DiseaseHolistic Management of Gynecological Cases in Cipto Mangunkusumo HospitalDiagnostic Approach and Successful Management of Cervical Tuberculosis: A Case ReportIndex.

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Book SynopsisPreeclampsia: Risk Factors, Pathogenesis and Potential Treatments investigates the clinical, anamnestic, and biochemical predictors of preeclampsia. As such, a prognostic model based on the co-use of the studied predictors has been developed for the early prediction of late-onset moderate preeclampsia. The authors summarize some theories suggested to explain the pathogenesis of preeclampsia. The pathogenesis of preeclampsia has not yet been fully clarified and it remains a disease of theories. Furthermore, as it is a human-specific disease, the lack of one-on-one animal modeling and many other factors contribute to poor understanding of the disease pathophysiology. Additionally, this collection explores the possibilities of the maternal and fetal heart rate variability usage at all stages of management among pre-eclamptic women in a three-stage system. The concluding review includes sources of literature on the pathogenesis, management and long-term consequences of pre-eclampsia.

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Book SynopsisEndometriosis is a chronic benign estrogen-dependent disease which is characterized by the presence of endometriotic glands and stroma outside the uterine cavity. It affects women during reproductive age, but it may also be diagnosed in menopausal women. Endometriosis can be asymptomatic; but most frequently it can be responsible for pain symptoms and/or infertility, severely impacting women' quality of life. Overall, clinical presentation depends on the location of endometriotic lesions: intestinal symptoms can occur in case of bowel nodules whereas urinary symptoms can occur in case of urinary tract endometriosis. At the moment, the exact prevalence of endometriosis is unknown because its definitive diagnosis requires surgery and histological evaluation. It has been estimated that this benign chronic disease affects at least 3.6% of reproductive age women; however, its prevalence could significantly increase considering women suffering from dysmenorrhea, chronic pelvic pain and/or infertility. The etiology of endometriosis is unclear: various factors, such as multiple abnormalities of the immune system, genetic factors and environmental factors may influence women' susceptibility to develop this chronic disease. Although the gold standard for the diagnosis of endometriosis is the pathological evaluation of surgical biopsies or specimens, today transvaginal ultrasonography is largely employed to reliably identify the presence of deep infiltrating endometriosis or ovarian endometriomas. The aim of the surgery for endometriosis is to restore the normal anatomy by removing endometriotic lesions and by performing adequate removal of abdominal adhesions. However, surgery, in case of deep infiltrating implants, can be rather challenging for gynecologists due to the complexity of pelvic adhesions involving several structures and it may be characterized by rare but not negligible urological, intestinal, neurological and vascular complications. Furthermore, pain may recur after conservative surgery for endometriosis. Although surgery is obviously required in cases of ureteral stenosis, bowel occlusion or ovarian cysts with doubtful characteristics of malignancy, medical therapy, and, particularly, hormonal therapies, are the initial therapeutic approach today for most patients with endometriosis-related pain. Long-term medical therapy for endometriosis aims to minimize the production and action of estradiol, inhibiting the production of cyclic hormones from the ovaries. Numerous medical options (such as estroprogestins, progestins, gonadotropin- releasing hormones analogs and antagonists) are available for treating women with endometriosis: the choice of the most suitable compound is based on several factors, such as intensity of pain, age, desire to conceive, costs, route of administration and impact of the endometriosis on work capacity, sexual function and quality of life of each women. Currently, research is focused on finding new innovative targets to treat this benign chronic disease; in fact, it is well known that development, maintenance and progression of endometriosis depend on a variety of aberrant mechanisms including cell proliferation, immune function, apoptosis, invasion capacity and angiogenesis. The aim of this book is to give an accurate overview on pathogenesis, diagnosis and therapy of endometriosis.Table of ContentsPreface; Environmental Factors and Endometriosis: Is There a Need or Possibility for a Change?; Pathogenesis of Endometriosis; Is Macrophage Polarization Important in Pathogenesis of Endometriosis?; Advances in Endometriosis Diagnosis: How Far Can Molecular Biology Help Us?; Quality of Life, Sexual Function and Couple Relationship in Women with Endometriosis and Chronic Pelvic Pain; Endometriosis: Comprehensive Overview on Diagnostic and Therapeutic Options; First-Line Medical Therapies for the Treatment of Endometriosis; Second-Line Medical Therapies for the Treatment of Endometriosis; Experimental Drugs in Endometriosis Therapy; Hormonal Therapies before In vitro Fertilization in Patients with Endometriosis; Bowel Endometriosis: Epidemiology of a Challenging Disease; Surgical Treatment of Bowel Endometriosis; Rectovaginal Deep Endometriosis: Planning the Right Surgical Approach; Urinary Tract Endometriosis: Clinical Presentation and Diagnosis; Cesarean Scar Endometriosis; Impact of Endometriosis on Pregnancy; Appendix I; Index.

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Book SynopsisThis is the first book that provides a comprehensive and in-depth account of the current state of knowledge on the ovarian reserve and its clinical applications in gynaecology and reproductive medicine. Ovarian reserve is a term commonly used to reflect the total number of remaining primordial follicles, which determines a womans fertility potential. Since its emergence in the late 1980s during the early days of assisted reproduction technology, the concept of ovarian reserve has continued to gain importance in clinical practice and research, as reflected by the exponentially growing number of publications on the topic. A wide range of ovarian reserve markers have been introduced over the years, starting with serum follicle stimulating hormone level in 1988 and most recently anti-Müllerian hormone in 2002. This book starts with a detailed background on the physiology of the ovarian reserve including early ovarian development, follicular dynamics, and the natural history of primordial follicles. This is followed by a comprehensive account of the various biochemical, sonographic, and dynamic markers and their current applications. A special chapter is devoted to anti-Müllerian hormone, which is the most extensively researched and widely used ovarian reserve marker. The role of anti-Müllerian hormone and its clinical utility in polycystic ovarian syndrome is presented in a separate chapter. The book then explores the clinical applications of ovarian reserve testing in various reproductive disorders, including early ovarian aging, diminished ovarian reserve (pathological and iatrogenic), poor ovarian response during assisted reproduction technology, and premature ovarian insufficiency.Table of ContentsIntroduction: The Concept of Ovarian Reserve; Natural History of the Primordial Follicles; Ovarian Reserve Testing; Anti-Müllerian Hormone; Anti-Müllerian Hormone and Polycystic Ovarian Syndrome; Diminished Ovarian Reserve; Ovarian Reserve and IVF: The Problem of Poor Ovarian Response; Premature Ovarian Insufficiency; References.

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Book SynopsisAdolescent sexuality and gynecologic care of young patients are topics which make most clinicians uncomfortable. This is due to a lack of knowledge and training in many circumstances. Assumptions based upon knowledge of adult gynecology alone may be hazardous for pediatric and adolescent patients. These children and young women often do not have access to specialists who are able and willing to care for their gynecologic issues at an appropriate level. The primary care setting is often the most comfortable venue for a number of these patients. The concept for this book was to provide a reference for primary care providers without highly specialized gynecology textbooks, just to focus on what providers tackle on a daily basis. The first edition was well received and the feedback was good. In the 10 years since the first edition was published, our knowledge has improved and many new methods, medications and devices were added to daily practice. Those changes prompted the Editors to provide an updated version of the book, while keeping its essence intact.Table of ContentsForeword; Dedication; Preface; Pediatric and Adolescent Sexuality: An Overview; Office Pediatric Gynecology; Gynecologic Endocrinology; Genetic Syndromes in Adolescent Gynecology; Child Abuse and Maltreatment; Breast Disorders in Children and Adolescents; Menstrual Disorders in Adolescent Females; Contraception: Updates; Pregnancy and Abortion; Sexually Transmitted Diseases/Infections; Ovarian Tumors in Children and Adolescents; The Female Athlete; Postpartum Depression; Gynecological Features of Eating Disorders; About the Editors; About the Department of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, Michigan, United States; About the National Institute of Child Health and Human Development in Israel; Index.

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Book SynopsisThis book offers a valuable clinical resource for health professionals and researchers. It gives an overview about the pivotal role played by High Molecular Hyaluronic Acid (HMW-HA) during pregnancy and its applications in the gestational period. Hyaluronic acid is a critical component of the extracellular matrix (ECM) and one of the most interesting, versatile and useful natural molecules in almost all areas of biology. As widely reported, HA has a pivotal role in several phases of pregnancy, from fertilisation to labour and it displays several regulatory activities and functional properties based on its different molecular weight. While low molecular weight hyaluronic acid (LMW-HA) is widely used in gynaecology for menopause-related symptoms or in association with physical treatments (eg: radiation therapy) to counteract the onset of adverse events, HMW-HA has been poorly evaluated as clinical treatment. Its physiological presence in the extracellular matrix of all the main organs and tissues involved in pregnancy (uterus, cervix, placenta, decidua, chorion, amnios, ovarium etc..) suggests the importance of this molecule for a successful gestation. Several papers, in particular, shed light on its importance for blastocyst adhesion and implantation, for an efficient immune tolerance and for the correct development of haemo-lymphatic system. It has been demonstrated that HMW-HA has regulatory activity on the PGRMC1 expression, a specific progesterone receptor expressed in maternal and foetal-maternal interface tissues, involved in uterine quiescence. On these premises, the administration of HMW-HA may represent an interesting treatment opportunity for the prevention of recurrent miscarriage and pre-term birth (PTB) in patients with risk factors. The high safety profile of HMW-HA further supports its administration in pregnancy. All these interesting topics will be discussed and deepened in this book, giving the opportunity to explore in detail every aspect of this effective and attractive molecule, thus helping physicians to assess the state of connective tissues in pregnancy and to evaluate the risk for the onset of gestational complications.Table of ContentsPreface; Properties and Physiological Role of Hyaluronic Acid; Hyaluronic Acid in Obstetrics: Role in Physiological Pregnancy; Effect of Hyaluronic Acid Treatment in Maintaining the Physiological Pregnancy: Preclinical Evidence; Safety of Hyaluronic Acid in Pregnancy; Use of Hyaluronic Acid in Assisted Reproduction Techniques; Role of Hyaluronan in Fetal Development; Hyaluronic Acid in the Development of the Gut and Protection Against Necrotizing Enterocolitis; About the Editor; Index.

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Book SynopsisCancer during pregnancy is a rare event, occurring approximately once per 1,000 pregnancies annually, corresponding to 0.07% to 0.1% of all malignant tumours. The incidence of cancer in pregnancy is increasing maybe due to trends in delayed childbearing. The most common malignancies associated with pregnancy are, in order of decreasing frequency, melanoma and breast cancer, cervical cancer, lymphomas and leukaemias. Melanoma, hematopoietic malignancies and lung cancer are the only cancers that have been reported to metastasize to the placenta and foetus, while melanoma accounts for almost one third of all cases. Imaging during pregnancy should consider risks to the foetus. Treatment of cancer can often be safely administered with good maternal and foetal outcomes. Chemotherapy, radiotherapy, and surgery must be adapted to the pregnancy state. Psychological support is needed at all levels of care. In addition, the diagnosis of cancer during reproductive age is increased, so procedures for counselling women with newly diagnosed cancer for fertility preservation are necessary. Due to high survival rates and high quality of life after cancer, women should be given the opportunity to plan motherhood after cancer actively. This work will provide an updated review of the diagnosis, staging and treatment options for cancer during pregnancy and the tools for a complete oncofertility counselling.Table of ContentsPreface; Oncofertility; Fertility Sparing Procedures; Taking Care of Women with Cancer During Pregnancy; Psychological Aspects in Women with Cancer and Pregnancy; Imaging Procedures in Pregnancy for Pre-Invasive and Invasive Lesions in Gynecological Cancers; Diagnostic Methods for Neoplastic and Pre-Invasive Lesions of Non-Gynaecological Neoplasms in Pregnancy; Monitoring Pregnancy (In Patients with History of Cancer and Diagnosis of Cancer); Lactation in Cancer; Breast Cancer and Pregnancy; Anticancer Therapies During Pregnancy: Focus on Breast Cancer; Supportive Care in Pregnancy; Radiation Therapy and Pregnancy; Index.

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Book SynopsisInfectious Pregnancy Complications deal with the co-occurrence of pregnancy and an infection. The infection may precede or follow fertilisation. This book presents the latest research in the field.

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Book SynopsisThis book examines working memory in pre-term and full-term infants at eight months after the expected date of delivery. Although numerous studies have reported that the overall development of pre-term infants is comparable to that of full-term infants at the same corrected age, it is unclear to what extent the development of specific cognitive abilities is affected by pre-maturity and/or other factors such as medical complications. As pre-term infants have a high rate of learning difficulties, it is possible that factors associated with pre-maturity specifically affect the development of some regions of the brain associated with working memory.

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Book SynopsisThis book represents an attempt to review the most recent knowledge concerning basic processes occurring in the most important female reproductive organ -- ovary and their regulators. The most important processes (ovarian cyclic changes and oogenesis), as well as their extracellular (hormones and growth factors) and intracellular (protein kinases, transcription factors, small RNAs) regulators are described. Data concerning processes or substances well described in previous reviews are summarised here in a short form with references to corresponding reviews.

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Book SynopsisMiscarriage is a common problem in obstetrics and often experienced in woman''s life. It occurs in about 10 percent of pregnancy and is more frequent with increasing age and in women with previous miscarriages. It has many clinical forms and different known causes, although most miscarriages remain unexplained. When counselling a patient, Doctors share anguish with their patients when they are compelled to inform them on the causes remained unexplained and on the scarce chances to prevent the recurrence. All this triggered the authors to plan and make a book on miscarriages, wishing they may add knowledge to doctors and hope to families who experience the problem.

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Book SynopsisIn this book, the authors present new developments in childbirth research. Topics discussed in this compilation include the theoretical and research findings on the psychopathology during transition to parenthood as a critical life event; the voices of postnatal women and how their experiences enhance antenatal practice; a sociological understanding of women''s childbirth discourses; ethical analysis on therapeutic abortion for foetal abnormality; the use of placental blood in term and pre-term new-borns; self-efficacy theory and intervention in childbirth; and anal sphincter damages in childbirth.

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Book SynopsisThis book was written to satisfy the rising need for epidemiology oriented clinicians. It focuses on essential aspects of perinatal medicine in a straightforward accessible manner. It gives the epidemiological perspectives on maternal and foetal morbidities in addition to peripartum and neonatal complications. Chapters discuss epidemiology of diabetes mellitus during pregnancy, hypertensive disorders, ectopic pregnancy, pre-term delivery, placental problems, epidemiology of obesity during pregnancy, intra-uterine growth restriction and maternal and perinatal mortality. Written by international experts, this sensible guide draws on evidence-based data in perinatal medicine. This book is a valuable resource for a broad spectrum of clinicians and healthcare professionals dealing with perinatal medicine. Medical and nursing students, as well as residents in obstetrics and paediatrics may largely benefit from it at various stages of their training.

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Book SynopsisThe primary function of the mammary gland is to provide nutrition for the young in the form of milk protein and fat. However, there are other benefits that are provided by lactation, such as the provision of immune factors that are secreted into the milk, which provide protection from infection. In this book, the authors discuss the natural processes, physiological response and role in maternity of lactation. Topics include gene expression in the mammary gland; human milk oligosaccharides and their health effects; the role of micro-RNAs in the lactation process; hormonal control of lactation, the role of breastfeeding in lactation; and Wnt signalling and ultrasound in lactation.

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Book SynopsisEndometrial cancer is the most common gynecological malignancy after breast cancer in developed countries. Its incidence is steadily rising and, now, the lifetime risk of developing endometrial cancer in the industrialized areas is about 23%. This book deals with the main aspects of disease management, including the perspectives for primary and secondary prevention, and the most recent interpretation of its pathogenesis. The management of endometrial cancer continues to evolve as we better understand tumour biology and more widely apply what evidence-based medicine comes from. This book may be of interest and a useful update for any health provider involved in gynaecological cancer care.

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Book SynopsisThis book aims to become a useful tool in the field of gynaecological oncology providing the most up-to-date research on non-epithelial ovarian tumours, including the recent data on pathogenesis and the current strategies for diagnosis, treatment, and follow-up. The authors present and review important data on rare and various primary ovarian neoplasms such as the many subtypes of germ cell tumours, of the most important subtypes of Sex cord -Stromal tumours and the rare mixed forms of Germ cell and Gonadal Stromal tumours. Non-specific mesenchymal tumours of the ovary are reviewed, as well as Secondary neoplasms, metastatic to the ovary from various sites (extragenital and genital primaries).

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Book SynopsisInfertility affects about 15% of couples in western societies. In addition to isolation, infertility challenges women''s sense of identity, expectations of their life trajectory and their perceived value in society. This book presents current research on the genetic factors, treatment risk and benefits, and social and psychological consequences of infertility. Topics include the traditional Chinese medicine approach to fertility management; adverse outcomes of assisted reproduction techniques; the impact of follicular fluid components and embryo-endometrial cross-talk on the oocyte quality or embryo viability; iatrogenic damage incurred during fertility treatment upon gamete competence and embryonic viability; genetic factors of male infertility; animal models for studying female infertility; and treatment of endometriosis associated with infertility.

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Book SynopsisThe menstrual cycle is the scientific term for the physiological changes that occur in fertile women and other female primates for the purposes of sexual reproduction. In this book, the authors discuss the signs and symptoms, psychological/behavioural changes and abnormalities of the menstrual cycle. Topics include the evolution of the menstrual cycle with a focus on the role of the luteal phase, extended sexual receptivity and the concept of concealed ovulation; functional and structural brain alterations associated with menstrual pain; premenstrual dysphoric disorder (PMDD) and premenstrual syndrome (PMS); the fluctuations on appetite and food intake that occur during the female reproductive cycle; and assessing energy intake and physical activity energy expenditure during the menstrual cycle.

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Book SynopsisThe placenta plays an essential role in childbirth. It becomes disposable after the baby is born which makes it the only organ in the human body that serves a vital function and then becomes obsolete. It is an extremely complex piece of biological equipment which allows the mother''s and the baby''s blood to come into very close contact, without mixing, to supply nutrients and oxygen to the baby, and move waste products like carbon dioxide back from baby to mother. Thus, the placenta acts as the lung, kidney and digestive system for the baby. The placenta also plays an important role in hormone production. Human chorionic gonadotropin is produced by the placenta and can be found in the baby''s blood as early as 10 days into pregnancy. The placenta is also responsible for the production of other hormones including oestrogen and progesterone and protects the baby from possible infection or from damage by substances found in the environment or used by the mother, such as alcohol, drugs, pollutants and endocrine disrupters. This book presents the reader with a comprehensive, well written and informative collection of chapters written by experts from around the world. It will be a valuable asset for anyone interested in reproduction and pregnancy and wanting to access excellent reviews as well as the most current discussion of the biology and medicine of the placenta.

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Book SynopsisIn this book, the authors present current research in the study of ovulation detection, its signs, symptoms and outcomes. Topics discussed in this compilation include the importance of up and down regulation of receptors for FSH, progesterone and GnRH in the ovary, endometrium and lymphocytes in correcting various ovulatory disorders and achieving live deliveries; polycystic ovary syndrome and implications in metabolic disorders; cancer risk of drugs for ovarian stimulation; alternatives to laparoscopic ovarian drilling for ovulation induction in clomiphene resistent women with polycystic ovary syndrome; reproductive outcomes and obesity; ovarian hyperstimulation syndrome and a focus on neurovascular complications; and new methods for ovulation detection.

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Book SynopsisGlobally, cervical cancer is the second leading cause of death for women with cancer. This is a tragedy in part because cervical cancer affects women usually a decade sooner than other cancers when those women are in their reproductive years and in the prime years in the labour force. While screening with the Pap test or other more recently evaluated tests have resulted in low cervical cancer rates in high resource countries, the lack of screening options in low resource countries means that many women present with symptoms reflective of advanced disease and so the chance of survival is low even with aggressive treatment. In this book, we have an international spectrum of authors from both high and low resource settings. We review the risk factors that lead to cervical cancer. We discuss novel screening techniques including HPV testing. We present the capacity for HPV vaccines to markedly reduce cervical cancer rates. Planning and implementing an organised cervical screening program and the assessment of quality indicators as a means of evaluation is outlined. In this book, we discuss novel operative options in early stage invasive cervical cancer as a means of preserving fertility. Also, we discuss the role of neoadjuvant chemotherapy as a means of down staging the disease. The role of surgically staging women to define more advanced disease is outlined including options for management of metastatic and/or recurrent disease with chemotherapy and targeted therapies. The special situation of women found to be pregnant during the diagnosis of pre-invasive or invasive cervical cancer; and the diagnosis and management principles are reviewed. Just as poliomyelitis has almost been eliminated in the lifetime of one generation, we look forward to the elimination of oncogenic HPV and its deadly ramifications particularly for women exposed to this virus.

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Book SynopsisThis book represents an attempt to review the most recent knowledge concerning basic processes occurring in the most important female reproductive organ -- the ovaries and their regulators. The most important processes (ovarian cyclic changes and oogenesis), as well as their extracellular (hormones and growth factors) and intracellular (protein kinases, transcription factors, small RNAs) regulators are described. Data concerning processes or substances well described in previous reviews are summarised here in a short form with references to corresponding reviews.

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Book SynopsisIn this book the authors present current research in the study of foetal development and its stages of growth, maternal influences and potential complications. Topics discusses in this compilation include the equine foetal development, fetomaternal interaction and potential complications during pregnancy; comparative anatomy, development and functional significance of the mammalian yolk sac; influence of exercise training on e-NOS expression, nitric oxide production and mitochondrial function in the human placenta; maternal melamine and foetal development; and immunolocalisation of syntaxin2 in sinusoidal endothelial cells during mouse liver development.

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Book SynopsisA miscarriage can be defined as a pregnancy that ends spontaneously before the foetus has reached a viable gestational age. There are two types of miscarriages: sporadic (SM) and recurrent (RM). RM is defined by most clinicians as three or more consecutive miscarriages. In this book, the authors discuss topics that include prevention of recurrent miscarriages; auto-immunity and recurrent miscarriages; the efficacy and safety of Chinese medicines for threatened miscarriage; Chinese herbal medicines for recurrent miscarriage; and the genetics of miscarriages.

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