Education Books

Book SynopsisAlthough it appears second in the "New Testament", "Mark" is generally recognized as the first Gospel to be written. This work points out, the "Gospel of Mark" can be understood only against the backdrop of the apocalyptic atmosphere of the Jewish rebellions of 66-73 ce, during which the Roman army destroyed the Temple of Jerusalem (70 ce).Trade Review"The long-awaited completion of the Marcus commentary on Mark has been well worth the wait. It provides the serious student of Mark one of the best commentaries available for the study of this Gospel. . . . Any serious student of the Gospel of Mark should possess this commentary."—Robert H. Stein, Journal of the Evangelical Theological Society -- Robert H Stein * Journal of the Evangelical Theological Society *

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Book SynopsisMost of us walk through each day expecting few surprises. If we want to better ourselves or our lives, we map out a path of gradual change, perhaps in counseling or psychotherapy. Psychologists William Miller and Janet C'de Baca were longtime scholars and teachers of traditional approaches to self-improvement when they became intrigued by a different sort of change that was sometimes experienced by people they encountered--something often described as a bolt from the blue or seeing the light. And when they placed a request in a local newspaper for people's stories of unexpected personal transformation, the deluge of responses was astounding. These compelling stories of epiphanies and sudden insights inspired Miller and C'de Baca to examine the experience of quantum change through the lens of scientific psychology. Where does quantum change come from? Why do some of us experience it, and what kind of people do we become as a result? The answers that this book arrives at yield remarkable insights into how human beings achieve lasting change--sometimes even in spite of ourselves. Trade ReviewBill Miller and Janet C'de Baca have written a wonderful book. Not since William James's Varieties of Religious Experience has there been such a psychologically penetrating book on spiritual experience. --George E. Vaillant, MD, Harvard Medical School Although many people spend years struggling to fix personal problems, some people undergo sudden, dramatic, and nearly instantaneous change. This book tells their stories and identifies the core features of these transformational changes. The idea of quantum change is arguably among the most exciting in psychology, since it challenges both common sense and clinical lore. This book will appeal to anyone interested in psychological change, transformation, or the human condition. In other words, this book is for everyone. --Todd F. Heatherton, PhD, Associate Professor, Department of Psychological and Brain Sciences, Dartmouth CollegeReading Quantum Change is a mystical experience of its own. This is an exceptionally well written book that I found inspirational, enlightening, and a 'must read.' After reading this book, don't be surprised if you think about change in a new way. --Monty Roberts, author of the New York Times best seller, The Man Who Listens to Horses -Table of ContentsI. The Context1. Something Old, Something New2. The Landscape of Quantum Change3. BeforeII. Insights4. The Insightful Type of Quantum Change5. Boom6. Taking the AA Train7. A Mirror and Two Roses8. Awakening9. RipplesIII. Epiphanies10. The Mystical Type of Quantum Change11. The Reluctant Mystic12. Something Like a Star13. A Voice in the Fireplace14. At Pecos15. TrampolineIV. Reflections16. After17. Are Quantum Changes Always Positive?18. What Happened?19. Messages to HumankindEpilogueAn InvitationAppendix. Values: What Matters Most to You?Notes

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Book SynopsisThis trusted bestseller provides all the information needed to understand binge eating and bring it under control, whether you are working with a therapist or on your own. Clear, step-by-step guidelines show you how to: *Overcome the urge to binge. *Gain control over what and when you eat. *Break free of strict dieting and other habits that may contribute to binges. *Establish stable, healthy eating patterns. *Improve your body image and reduce the risk of relapse. This fully updated second edition incorporates important advances in the understanding and treatment of eating disorders. It features expanded coverage of body image issues and enhanced strategies for achieving--and maintaining--a transformed relationship with food and your body. Association for Behavioral and Cognitive Therapies (ABCT) Self-Help Book of Merit. Included in the UK National Health Service Bibliotherapy Program.Trade Review"By any standard, Dr. Fairburn is the leading authority in our field, so who better to write the definitive book on binge eating? This program is based on vast clinical experience, numerous clinical trials, and a breadth of perspective that few possess. You can trust this book. It is a landmark."--Kelly D. Brownell, PhD, coauthor of Food Fight; Robert L. Flowers Professor of Public Policy and Professor of Psychology and Neuroscience, Duke University "It is hard to improve a classic, but that is exactly what Dr. Fairburn has done. Overcoming Binge Eating, Second Edition, expands on the author's highly effective treatment. This self-help guide is filled with specific tools that can help reverse unhealthy habits that have trapped you for years. Dr. Fairburn helps you maintain regular eating habits, distract yourself from cravings, stop emotional eating, and address body image issues. My colleagues and I will be recommending this book to all of our clients who feel their eating is out of control."--Robert L. Leahy, PhD, author of The Worry Cure "This invaluable second edition incorporates recent advances in the treatment of binge eating, including new strategies for dealing with body image issues. I recommend this user-friendly book wholeheartedly."--G. Terence Wilson, PhD, Oscar K. Buros Professor of Psychology, Rutgers, The State University of New Jersey "In this gem of a book, now thoroughly revised, Dr. Fairburn draws on decades of clinical experience and research. This is a powerful resource for anyone who wants to achieve lasting self-change."--Ruth H. Striegel, PhD, Editor-in-Chief, International Journal of Eating Disorders "Readers have posted online calling the previous version of this book 'a godsend' and 'the best book out there.' This substantially revised second edition is as good as the first and sets the standard for self-help books. This clearly written, practical guide is invaluable for anyone suffering from binge eating problems."--Roz Shafran, PhD, Institute of Child Health, University College London, United Kingdom "This is the book that every patient and parent should read in order to understand what drives eating disorder behaviors. In this remarkable guide, Dr. Fairburn translates decades of research on therapy into steps for lasting change."--Julie Lesser, MD, Medical Director, Center for the Treatment of Eating Disorders, Children's Hospitals and Clinics of Minnesota and Abbott Northwestern Hospital -“This book has proved invaluable to individuals who struggle with binge eating, and it has become a trusted tome on the shelf of many therapists, dietitians, and physicians who want to prescribe a non-invasive, evidence-based approach to treating their patients with an eating disorder….Although Fairburn himself still advocates for paper-and-pencil monitoring (p. 134), the self-help program presented in Overcoming Binge Eating could easily be used synergistically with new smartphone applications…that facilitate real-time tracking of food intake, thoughts, and feelings….Even if the dog-eared, highlighted original is still sitting on your office shelf, treating yourself to the second edition is well worth the modest price.”--Academy for Eating Disorders Forum, 1/1/2014Table of ContentsIntroduction: This Book and How to Use ItI. Binge Eating Problems: The Facts1. Binge Eating2. Eating Problems and Eating Disorders3. Who Binges?4. Psychological and Social Aspects5. Physical Aspects6. What Causes Binge Eating Problems?7. Binge Eating and Addiction8. The Treatment of Binge Eating ProblemsII. An Enhanced Self-Help Program for Those Who BingeGetting ReadyStarting WellRegular EatingAlternatives to Binge EatingProblem SolvingTaking StockDietingBody ImageEnding WellAppendix I. Obtaining Professional Help for an Eating ProblemAppendix II. Calculating Your Body Mass IndexAppendix III. If You Are Also OverweightAppendix IV. Tackling "Other Problems"Appendix V. A Note for Relatives and FriendsAppendix VI. A Note for TherapistsFurther Reading

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Book SynopsisMaster the techniques of infant massage and incorporate this joyful and wonderful healing art into your baby’s life with this revised and updated edition.For generations, mothers around the world have known that the soft touch of their hands soothes, calms, and communicates their love to their babies. The latest scientific research confirms that physical affection is vital to the development and wellness of children—easing discomfort, releasing tension, improving sleep, helping premature infants gain weight, even aiding asthmatic children to improve their breathing. Now Vimala McClure, founder of the International Association of Infant Massage, has revised and updated her beloved classic. Inside you’ll find • specific routines tailored to help relieve colic, fever, and chest and nasal congestion • easy-to-follow instructions and photographs demonstrating each step • new information on the benefits of skin-to-skin contact

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Book SynopsisChallenging the common gene-centric approach to organisms, this book articulates a relativistic theory of biology. It is grounded in up-to-date biological research and rigorous application of mathematics to biology; however, it is presented in a non-technical manner for the general reader, and requires no familiarity with complex biology, mathematics or philosophy.Trade Review'Among its many merits, this remarkable book deserves to become a classic text in the philosophy of science. Almost alone among philosophers of science, Noble is a practising scientist; and unusually among practising scientists, he is an accomplished philosopher. His book brings out, with unparalleled clarity, how the scientific endeavour involves not only empirical inquiry but also conceptual structure. Noble shows how, on the negative side, popular presentations of sound biological results may be vitiated by bad metaphysics, and how, on the positive side, science and philosophy may extend the boundaries of knowledge by a unified epistemology. He ends, however, with a salutary warning that there may well be a limit to the human capacity to know the answers to ultimate questions.' Sir Anthony Kenny, University of Oxford'I think this a marvellous book. Denis Noble emphasises that genes, organs and systems dance to the tune of the organism and its social and physical environment. He sets the relativity of biology in a remarkable scientific sweep, ranging from cosmology to human belief systems. He reminds me of another great biologist, C. H. Waddington, to whom Noble pays handsome tribute. Writing with clarity and charm, Noble attempts to break down silos of knowledge inhabited by scientists who fail to come out and engage with others. … Broadening minds in an era of intense specialisation is more important than ever. Noble deserves to be successful in his desire to do just that and I hope that he will be.' Sir Patrick Bateson, University of Cambridge'In my view Dance to The Tune of Life is a 'must read'. In it Denis Noble lucidly deconstructs how and why reductionism came to prominence in biology and led to the current state of molecular Humpty-Dumptyism. His central idea that there is no privileged level of causation is the first conceptual step to putting Humpty Dumpty back together again.' Michael J. Joyner, Mayo Clinic, Minnesota'Denis Noble is renowned for his mission to reintegrate the physiological sciences with mainstream biology, including evolutionary theory. His new book combines clear exposition of basic principles with many valuable examples. He gives the reader, general or expert, a completely new view of life.' Yung E. Earm, Seoul National University, South Korea'Dance to the Tune of Life is one of the most fascinating and impressive books I have ever read. Denis Noble, a world-renowned physiologist and systems biologist, has revolutionized our traditional notion of the nature of life. The title Dance to the Tune of Life mirrors the essence of the argument of the book. The life emerges from numerous biological processes at different scales and levels. Such actors and actresses, stage properties, and stage are not separately present they act together in harmony, dancing to a tune with a music performed by an orchestra, an organism. By describing his research experiences and achievements on the cardiac rhythm evolutionary biology, medicine, and philosophy, Denis has not only provided us with very modern knowledge of the biological reactions and their network but also described to us the nature of life. I believe that this book impacts everyone involved in biomedicine.' Yoshihisa Kurachi, Osaka University, Japan'Having demolished the 'Selfish Gene' fiction, Noble in this marvelous book moves both science and philosophy from an antiquated 'either/or' static model to an 'and' model. 'Dance' shows elegantly and brilliantly that from the miracle of the ancient symbiosis of mitochondrial bacterial remnants in human cells, through the rock-solid interrelationship between genes and the feedback from the environment in all senses - from the core phenomenon of functional epigenetics, to the universe itself and our place in it - that we are, at heart, inter-beings, co-arising.' Samuel Shem, New York University'Denis Noble is a pioneer in understanding human physiology through quantitative studies linking behaviour across multiple scales of biological organization - from proteins to cells, tissues, organs and organ systems. These studies have led him to characterize biological function in terms of a Principle of Biological Relativity: there is no privileged level of causation in biology, because living organisms are multilevel open stochastic systems in which the behaviour at any level depends on higher and lower levels, and so cannot be fully understood in isolation. This engaging book defends this view in depth, and thereby also provides strong support for an extended synthesis of evolutionary theory that goes beyond the Modern Synthesis of Neo-Darwinism. It is highly recommended as a thoughtful study of the kind of complexity real living organisms display.' George Ellis FRS, University of Cape Town, South Africa'In this elegantly written and personal book world-renowned physiologist and systems biologist Denis Noble effectively argues for a fundamental revision of the theory of evolution. Against the reductionist, gene-centered approach of Neo-Darwinism, which has dominated biology for more than a century, Noble passionately pleas for a more integrated approach. Massively supported by recent postgenomic and epigenetic empirical research, Dance to the Tune of Life deepens and synthesizes ideas Noble earlier developed in The Music of Life. Biology beyond the Genome (2006) and subsequent writings. Just like Newtonian physics underwent a major transformation in the beginning of the 20th century due to Einstein's general theory of relativity, the life sciences are facing a no less fundamental transformation. Noble's book is a must read for anyone who wants to understand this transformation.' Jos de Mul, Erasmus University Rotterdam, Netherlands'… enlightening … The illustrations are both vibrant and clarifying, giving this title a sparkle that compels you to imagine how each concept fits into the larger scheme. I commend this author for relishing the subtle reminders of what makes this inquiry important. It's a best read.' D. Wayne Dworsky, San Francisco Book Review (www.sanfranciscobookreview.com)'… a very informative read … Noble's Dance to the Tune of Life is an illuminating account of why philosophy is necessary in doing science.' Sepehr Ehsani, Metascience'The narrative is remarkable … Dance to the Tune of Life is a marvellous text reflecting on the complexity of biology.' Anna Holderbaum, The BiologistTable of ContentsPreface; Acknowledgments; 1. The universe and the principle of relativity; 2. Biological scales and levels; 3. Biological networks; 4. Nature and origin of cells; 5. Blind chance and natural selection; 6. Biological relativity; 7. Dancing nucleotides: natural genetic engineering; 8. Epigenetics and a relativistic theory of evolution; 9. The relativity of epistemology: the meaning of it all; 10. Postscript; Glossary; Index.

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Book SynopsisTHE BOOK THATâS REVOLUTIONIZING HEALTH CARE IN AMERICAA groundbreaking prescription for reformâfrom a legendary leader in innovation.âœClear, entertaining, and provocative, The Innovatorâs Prescription should be read by anyone who cares about improving the health and health care of all.ââRisa Lavizzo-Mourey, MD, President and CEO, Robert Wood Johnson FoundationâœComprehensive in its vision, astute in its diagnosis, and clear in its guidance, The Innovatorâs Prescription offers strong medicine for a heath care system that is far from well.ââHarvey V. Fineberg, MD, President, Gordon and Betty Moore FoundationOur health care system is in critical condition. The Affordable Care Act has insured more Americans than ever, yet deductibles keep rising and costs continue to climb. Now more than ever, the industry needs a shot in the arm. It needs The Innovatorâs Prescription, the now-classic aTable of ContentsIntroduction CHAPTER 1:The Role of Disruptive Technology and Business Model Innovationin Making Products and Services Affordable and AccessibleCHAPTER 2:The Technological Enablers of Disruption CHAPTER 3:Disrupting the Hospital Business ModelCHAPTER 4:Disrupting the Business Model of the Physician’s Practice CHAPTER 5:Disruptive Solutions for the Care of Chronic Disease CHAPTER 6: Integrating to Make It Happen CHAPTER 7:Disrupting the Reimbursement System CHAPTER 8:The Future of the Pharmaceutical Industry chapter 9:Future Directions for Medical Devices and Diagnostic Equipment CHAPTER 10:The Future of Medical Education CHAPTER 11:Regulatory Reform and the Disruption of Health Care Epilogue Index

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Book Synopsis“This useful title, which will also work well as a circulating item, presents that something extra for fitness enthusiasts who want to become serious about their conditioning.” —Library Journal (starred review). The revolutionary series Anatomy of Exercise includes eight specialized titles that followed the first title, Anatomy of Exercise, each focusing on a specific sport or exercise programme. Since the release of the first book, the titles in this innovative series have sold over 250,000 copies. Compiling content from all nine titles, Encyclopedia of Exercise Anatomy enables the reader to tailor a personalized and professional programme that will meet specific needs. A runner can dip into yoga to improve his breathing; a muscle builder can shape her legs with cycling workouts; a gymnast can combine yoga with core stability and strength exercises, and a woman over 50 can design a programme that fits into her busy life. Comprehensive and informative, this big compendium includes these standard features: Full-body anatomy illustrations, front and back; Annotated full-colour anatomical illustrations for all exercises; Full-colour photographs of exercises; Visual identification of active and stabilizing muscles; Concise step-by-step how-to instructions and guidance; Level-of-difficulty modifications; “Best For” information boxes; Safety tips boxes; Pre-designed workouts; Visual index of exercises; Glossary of anatomical terms. For anyone who works on their fitness routines, whether at a gym, health club or in a sport personally, professionally or academically, Encyclopedia of Exercise Anatomy is the ideal resource for a lifetime of healthy living.Trade Review[Review of hardcover edition: ] [starred review] Fitness magazine editor and national bodybuilding champion Liebman's no-nonsense title goes back to the basics, educating users on how to do specific exercises, illustrating in anatomical sketches how the body is affected by them, and listing which exercises best prepare the body for various sports. Part 1 offers general comments and tips on exercise and nutrition as well as large-format computer-generated images (CGI) of the human body with its muscles labeled. The other sections of the book show exercises and stretches in a spread each, with one page offering a photo-illustrated how-to, and the opposite page featuring a CGI of the body at work with the relevant muscles highlighted. Most helpful is the segment of workouts, with instructions for two routines each for beginner, intermediate, and advanced practitioners who want to focus on a particular part of the body or prepare for a particular sport. The sports-specific entries ready readers for common pastimes such as baseball, cycling, and various martial arts but also for sports such as archery, hurling, and water polo. Closing the book are glossaries of English and Latin terms. VERDICT This useful title, which will also work well as a circulating item, presents that something extra for fitness enthusiasts who want to become serious about their conditioning.-- (10/15/2014)

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Book SynopsisMost illnesses start in the gut, including many you would not even think of!If your gut isn’t functioning right, it sets the stage for illness and disease. The gut, the gastrointestinal system, is designed to absorb nutrients that support our bodies and help us make energy, and get rid of things that we don’t need or are toxic. But what happens when the system breaks down? Leaky gut syndrome (LGS) occurs when the lining of the small intestine is damaged, allowing foreign compounds to escape into your bloodstream, which weakens your immune system and triggers autoimmune reactions.Traditional physicians don’t understand what LGS is, much less how to diagnose and treat it. In fact, it is estimated that more than 80 percent of people with chronic illnesses have leaky gut, an overgrowth of bad bacteria, or not enough good bacteria.Here are some symptoms that may be caused by LGS: Digestive complaints, acid reflux, IBS, Crohn’s disease Joint and muscle pain, arthritis Obesity and food allergies Headaches, depression, anxiety, ADHD Itchy skin, rashes, eczema, acne, rosacea, psoriasis In Heal Your Leaky Gut, Dr. David Brownstein will explain how the gut, like the brain, heart, and liver, needs to be properly nourished in order for it to function correctly. Simply stated, if your gut is not healthy, your immune system is going to suffer.Improving your gut health and taking fewer drugs will help you feel better and look younger, improve your brain function, and treat myriad medical conditions. This book will give you all the information you need to change what you are now doing so you can have optimal gut health and, as a result, overall health and well-being.

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Book SynopsisIron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health.The 4th edition of Iron Metabolism is written in a lively style by oTrade Review'This textbook is clearly a milestone which should be to hand for every researcher and scholar working on or interested in the biochemistry and clinical aspects of iron. Those needing to go further in depth on some specific aspects will find not only an excellent starting point but also their pathway through the impressive list of references at the end of each chapter.' Acta Cryst (International Union of Crystallography), November 2017Table of ContentsPreface xii 1 Solution Chemistry of Iron 1 1.1 Iron Chemistry 1 1.2 Interactions of Iron with Dioxygen and Chemistry of Oxygen Free Radicals 2 1.3 Hydrolysis of Iron Salts 5 1.4 Formation and Characterisation of Ferrihydrite 7 1.5 Ageing of Amorphous Ferrihydrite to more Crystalline Products 10 1.6 Biomineralisation 11 1.7 Magnetite Biomineralisation by Magnetotactic Bacteria 13 1.7.1 Biogenesis of the Magnetosome Membrane 15 1.7.2 Protein Sorting 15 1.7.3 Chain Formation 16 1.7.4 Biomineralisation 16 1.7.5 A Model for Magnetosome Formation 17 References 18 2 The Essential Role of Iron in Biology 22 2.1 Introduction: Iron an Essential Element in Biology 22 2.2 Physical Techniques for the Study of Iron in Biological Systems 25 2.3 Classes of Iron Proteins 29 2.4 Haemoproteins 29 2.4.1 Oxygen Carriers 30 2.4.2 Activators of Molecular Oxygen 34 2.4.3 Electron Transport Proteins 38 2.5 Iron–Sulphur Proteins 41 2.6 Non]haem, Non]Fe–S Proteins 48 2.6.1 Mononuclear Non]haem Iron Enzymes 48 2.6.1.1 Extradiol]cleaving Catechol Dioxygenases 49 2.6.1.2 Rieske Oxygenases 49 2.6.1.3 α]Ketoglutarate]dependent Enzymes 52 2.6.1.4 Pterin]dependent Hydroxylases 54 2.6.1.5 Miscellaneous Enzymes 55 2.6.2 Dinuclear Non]haem Iron Proteins 55 2.6.3 Proteins of Iron Storage, Transport and Metabolism 61 2.7 The Dark Side of Iron: Ros , Rns and Ntbi 62 2.7.1 ROS and RNS 63 2.7.2 NTBI and LPI 64 References 64 3 Microbial Iron Uptake 71 3.1 Introduction 71 3.2 Iron Uptake from Siderophores 74 3.2.1 Siderophores 74 3.2.2 Iron Transport across the Outer Membrane in Gram]negative Bacteria 78 3.2.3 Transport across the Periplasm and Cytoplasmic Membrane in Gram]negative Bacteria 86 3.2.4 Iron Uptake by Gram]positive Bacteria 92 3.3 Fe2+ Transport Systems 93 3.4 Iron Release from Siderophores in the Cytoplasm 97 3.5 Intracellular Iron Metabolism 98 3.6 Control of Gene Expression by Iron 101 References 108 4 Iron Acquisition by Pathogens 120 4.1 Introduction 120 4.2 Host Defence Mechanisms, Nutritional Immunity 121 4.3 Pathogenicity and PAIs 123 4.4 Pathogen]specific Iron Uptake Systems 125 4.4.1 Siderophores Associated with Virulence 125 4.4.2 Transferrin/lactoferrin Iron Uptake 126 4.4.3 Haem Iron Uptake 133 4.4.4 Ferrous Iron Uptake 138 4.4.5 Ferric Citrate Uptake by Bacillus cereus 141 4.5 Role of Fur and Fur Homologues in Virulence 141 4.6 Role of Pathogen Ecf Sigma Factors 141 4.7 Fungal Pathogens 143 References 146 5 Iron Uptake by Plants and Fungi 155 5.1 Iron Uptake by Plants 155 5.1.1 Introduction 155 5.1.2 Genome Sequencing 157 5.1.2.1 Quantitative Trait Loci 158 5.1.3 Iron Acquisition by the Roots of Plants 160 5.1.3.1 Non]graminaceous Plants 161 5.1.3.2 Graminaceous Plants 164 5.1.4 Long]distance Iron Transport 166 5.2 Iron Metabolism and Homeostasis in Plants 169 5.2.1 New Tools in Plant Research 169 5.2.2 Intracellular Iron Metabolism 170 5.2.3 Plant Iron Homeostasis 171 5.2.4 Diurnal Regulation of Iron Homeostasis 176 5.3 Iron Uptake, Metabolism and Homeostasis in Fungi 178 5.3.1 Introduction 178 5.3.2 High] and Low]affinity Iron Uptake Pathways 179 5.3.3 Siderophore]mediated Iron Uptake 184 5.3.4 Intracellular Iron Metabolism 185 5.3.5 Iron Homeostasis 186 References 190 6 Cellular Iron Uptake and Export in Mammals 205 6.1 The Transferrins 205 6.1.1 Introduction 205 6.1.2 The Transferrin Family 206 6.1.3 Structure of Transferrins 211 6.1.4 Transferrin iron Binding 215 6.1.5 Binding of other Metals by Transferrin 218 6.2 Cellular Iron Uptake 219 6.2.1 The Transferrin Receptors 219 6.2.2 The Transferrin to Cell Cycle and Iron Release 222 6.2.3 Iron Uptake from other Sources 228 6.3 Cellular Iron Export 230 References 236 7 Mammalian Iron Metabolism and Dietary Iron Absorption 247 7.1 An overview of Mammalian Iron Metabolism 247 7.1.1 Introduction 247 7.1.2 The Way Different Cells Handle Iron 249 7.2 Mammalian Iron Absorption 251 7.2.1 Introduction 251 7.2.2 The Intestinal Mucosa 252 7.2.3 Sources of Dietary Iron 253 7.2.4 Iron Loss and Effects on Uptake 255 7.3 Molecular Mechanisms of Mucosal Iron Absorption 256 7.3.1 Iron Uptake at the Apical Pole 256 7.3.2 Iron Transit through and Storage in Enterocytes 259 7.3.3 Iron Efflux across the Basolateral Membrane 259 7.3.4 Regulation of Iron Uptake by the Enterocyte 261 References 261 8 Intracellular Iron Utilisation 265 8.1 Intracellular Iron Pools 265 8.1.1 Introduction 265 8.1.2 The Cytosolic Labile Iron Pool (LIP) 266 8.1.3 Distribution of Iron in the Cytosol 268 8.1.4 Other Intracellular Iron Pools 269 8.2 Mitochondrial Iron Metabolism 271 8.2.1 Mitochondrial Iron Uptake and Storage 271 8.2.2 Mitochondrial Fe–S Protein Biogenesis 271 8.2.3 Maturation of Cytosolic and Nuclear Fe–S Proteins 275 8.2.4 Haem Biosynthesis 283 8.3 Haem Oxygenase 287 8.3.1 Structure and Catalytic Cycle 287 8.3.2 Activation of Haem Oxygenase 1 (HO]1) 292 References 292 9 Iron Storage Proteins 300 9.1 Introduction 300 9.2 The Ferritin Superfamily and Haemosiderins 301 9.2.1 The Ferritin Superfamily 301 9.2.2 Structure of Vertebrate and Invertebrate Ferritins 304 9.2.3 Plant and Bacterial Ferritins 308 9.2.4 Dps Proteins and Rubrerythrins 313 9.2.5 The Mineral Core 319 9.2.6 Haemosiderins 319 9.3 Iron Uptake and Release from Ferritin 320 9.3.1 Iron Uptake in Ferritins 320 9.3.1.1 Entry of Fe(II) into the Protein Shell 321 9.3.1.2 Oxidation of Fe2+ by Ferroxidase Sites 323 9.3.1.3 Mineralisation of the Iron Core 325 9.3.2 Iron Uptake in Dps Proteins 333 9.3.3 Iron Release from Ferritin 333 9.4 Biotechnological Applications of Ferritins 335 References 336 10 Cellular and Systemic Iron Homeostasis 346 10.1 Cellular Iron Homeostasis 346 10.1.1 Translational Control of Protein Synthesis 346 10.1.2 The IRE/IRP System 347 10.1.3 The IREs – distribution and Structure 348 10.1.4 Structural Features of IRP1 and 2 351 10.1.5 The IRE/IRP System Revisited – Iron Controls Iron 353 10.1.6 Metabolic Consequences of Mutations in Ires 357 10.2 Systemic Iron Homeostasis 357 10.2.1 Introduction 357 10.2.2 Hepcidin, the Key Player 358 10.2.3 Factors which Regulate Hepcidin Synthesis 360 10.2.3.1 Iron Availability 361 10.2.3.2 Inflammatory Stimuli 364 10.2.3.3 Erythropoietic Demand 364 10.2.3.4 Hypoxia 365 10.2.3.5 Endocrine Signals 366 10.3 Integration of Iron Homeostatic Systems 367 References 367 11 Iron Deficiency, Iron Overload and Therapy 376 11.1 Iron]deficiency Anaemia (Ida) 376 11.1.1 Introduction – The Size of the Problem 376 11.1.2 Causes of Ida 378 11.1.3 Clinical Stages and Diagnosis of Ida 380 11.1.4 Therapeutic Approaches 383 11.1.5 Anaemia of Chronic Disease (Acd ), Iron Refractory Ida (Irida ) and Anaemia of Chronic Kidney Disease (Ckd) 384 11.2 Hereditary Iron Overload 386 11.2.1 Introduction 386 11.2.2 Hereditary Haemochromatosis (Hh) 386 11.2.3 Causes of HH 387 11.2.4 Types of Haemochromatosis 388 11.2.4.1 Hfe]related (Type 1) Haemochromatosis 388 11.2.4.2 Juvenile (Type 2) Haemochromatosis 390 11.2.4.3 Tfr2]related (Type 3) Haemochromatosis 390 11.2.4.4 Ferroportin Disease 390 11.2.5 Therapy of Hereditary Haemochromatosis 391 11.3 Acquired Iron Overload 395 11.3.1 Introduction – Causes of Acquired Iron Overload 395 11.3.2 Mechanisms of Iron Toxicity 397 11.3.3 Evaluation of Iron Overload 398 11.3.4 Chelation Therapy for Acquired Iron Overload 400 11.3.5 Other Therapeutic Approaches 405 References 406 12 Iron and Immunity 418 12.1 Introduction 418 12.1.1 Innate Immunity 419 12.2 The Key Role of Macrophages 422 12.2.1 Overview 422 12.2.2 Macrophage Phenotypes 425 12.2.3 Microglia 426 12.3 Effect of Iron Status on Phagocytic Cell Function 429 12.3.1 Iron Deficiency 429 12.3.2 Iron Overload 430 12.4 Effect of Phagocytic Cell Function on Iron Metabolism 431 12.4.1 The IRE–Iron Regulatory Protein (IRP) System 431 12.5 Effector Molecules of the Innate Immune System 433 12.5.1 Toll]like Receptors 433 12.5.2 NF]κB 433 12.5.3 Hypoxia]Inducible Factor 1 (Hif 1) 434 12.5.4 Haem Oxygenase 435 12.5.5 DMT1, Nramp1 437 12.6 Adaptive Immunity 437 12.6.1 Cd8+ Lymphocytes and Cytotoxicity 438 12.6.2 CD4+ lymphocytes 438 12.7 Immune Function and other Factors 438 12.7.1 Iron Supplementation and Immune Function 438 12.7.2 Immune Function in the Elderly Population 439 12.7.3 Iron Overload and Immune Function 439 12.7.4 Thalassaemia 440 12.8 Concluding Remarks 440 References 440 13 Iron and Oxidative Stress 444 13.1 Oxidative stress 444 13.1.1 Introduction – Milestones in the History of Life 444 13.1.2 Reactive Oxygen Species (Ros ) and Reactive Nitrogen Species (Rns) 447 13.1.3 Cellular Defence Mechanisms Against Oxidative Stress 450 13.1.4 Role of ROS and RNS in Cell Signalling 460 13.1.5 ROS, RNS and Oxidative Damage 466 References 476 14 Interactions between Iron and other Metals 482 14.1 Introduction 482 14.2 Iron Interactions with Essential Metals 483 14.2.1 Copper 483 14.2.1.1 Introduction 483 14.2.1.2 Copper Acquisition and Metabolism 485 14.2.1.3 Copper Chaperones 486 14.2.1.4 Iron–copper Interactions 487 14.2.2 Zinc 494 14.2.2.1 Introduction 494 14.2.2.2 Iron–zinc Interactions 496 14.2.3 Cobalt 497 14.2.3.1 Introduction 497 14.2.3.2 Iron–cobalt Interactions 498 14.2.4 Manganese 500 14.2.4.1 Iron–manganese Interactions 500 14.2.5 Calcium 501 14.2.5.1 Iron–calcium Interactions 501 14.3 Iron Interactions with Toxic Metals 502 14.3.1 Lead 502 14.3.2 Cadmium 503 14.3.3 Aluminium 505 References 507 15 Iron Homeostasis and Neurodegeneration 516 15.1 Introduction 516 15.2 Brain iron 517 15.2.1 Brain Iron Homeostasis 517 15.2.2 Aging and Brain Iron Content 518 15.3 Iron and Neurodegeneration 522 15.3.1 Introduction 522 15.3.2 Adverse Effects of Iron in Neurodegeneration 522 15.3.2.1 Toxicity of ROS and RNS 522 15.3.2.2 Iron and Mitochondrial Function 523 15.3.2.3 Protein Aggregation 523 15.4 Neurodegeneration with Brain Iron Accumulation 524 15.4.1 Aceruloplasminaemia 524 15.4.2 Neuroferritinopathy 526 15.4.3 Other NBIAs 528 15.5 Other Monogenic Neurodegenerative Diseases 530 15.5.1 Huntington’s Disease 530 15.5.2 Friedreich’s Ataxia 532 15.6 Neurodegeneration Involving Multiple Genes 533 15.6.1 Parkinson’s Disease (PD) 533 15.6.2 Alzheimer’s Disease (AD) 535 15.6.3 Multiple Sclerosis (MS) 537 15.7 Intracerebral Haemorrhage 538 References 539 Concluding Remarks 544 Index 547

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Book SynopsisA new look at National Museums Scotland collections covering the period 800-1200: the fall of the Pictish kingdoms and rise of the Viking Age; the emergence of new players like Alba, Moray, Strathclyde, Galloway and the Norse Earldom of Orkney. Out of this turmoil were forged the roots of the kingdoms of Scotland and England.National Museums Scotland houses one of the most significant collections of Viking-age and early medieval artefacts in the world. This book offers new perspectives on star objects which have been on display for decades, and on lesser-known artefacts which have never been seen in public, and shows these in photographs taken specially for third part of The Glenmorangie Company Research Project.The previous two books coming out of the project are Early Medieval Scotland and Scotland's Early Silver.

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Book SynopsisâœYou wonât find a better textbook on public health than this. Comprehensive, authoritative, up-to-date, informative, and very readable. A must for all public health reading lists.âEmeritus Professor Mike Daube, Faculty of Health Sciences, Curtin University, Perth, Western AustraliaâœIn Issues in Public Health you will find detailed, evidence-based, contemporary discussion about the wide range of public health challenges facing public health professionals around the world.âMary Lyons, Senior Lecturer in Public Health, Liverpool School of Tropical Medicine, UKâœAn essential resource for anyone looking to understand the foundations of public health and its ongoing evolution.âDr Sandro Galea, Dean and Robert A. Knox Professor at Boston University School of Public Health, USAWhat is public heTable of ContentsList of FiguresList of Tables Introduction to the Third EditionSection 1: Foundation of modern public health1. Population health: principles and conceptsMartin McKee, Fiona Sim and Alison Krentel2. Describing the health of a populationMarina Karanikolos, Martin McKeeSection 2: Determinants of public health3. Social determinants of healthMartin McKee4. The political determinants of healthNason Maani, May C.I. van Schalkwyk, Martin McKee5. The Commercial Determinants of HealthMay C.I. van Schalkwyk, Nason Maani, Martin McKee6. Health care as a determinant of healthMarina Karanikolos, Ellen Nolte, Martin McKee, Fiona SimSection 3: Contemporary issues facing public health7. Planetary HealthMay C.I. van Schalkwyk, Mark Taylor, Martin McKee8. The changing nature of infectious diseaseAlison Krentel, Sandra Mounier-Jack, Chris Bonell, Fiona Sim and Martin McKee9. Non-communicable diseasesHarry Rutter and Mark Taylor10. Armed conflict and Public HealthBayard RobertsSection 4: Public health practice11. Ethics and Public HealthThomas E. Novotny12. Information and public healthMay C.I. van Schalkwyk, Charlotte McKee, Nason Maani, Alison Krentel, Martin McKeeGlossary of termsSelf-assessmentIndex

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Book SynopsisAny Day Now will help you to understand what is next in God's prophetic planand encourage you with the promise that Jesus's return and the restoration of His people are just around the corner.

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Book SynopsisTable of ContentsList of abbreviations Introduction The top 100 drugs listed by system The top 100 drugs listed by indication The top 100 drugs (alphabetical listing) 5a-reductase inhibitors a-blockers Acetylcholinesterase inhibitors Acetylcysteine (N-acetylcysteine) Activated charcoal Adenosine Adrenaline (epinephrine) Aldosterone antagonists Alginates and antacids Allopurinol Aminoglycosides Aminosalicylates Amiodarone Angiotensin-converting enzyme (ACE) inhibitors Angiotensin receptor blockers Antidepressants, selective serotonin reuptake inhibitors Antidepressants, tricyclics and related drugs Antidepressants, venlafaxine and mirtazapine Antiemetics, dopamine D2-receptor antagonists Antiemetics, histamine H1-receptor antagonists Antiemetics, serotonin 5-HT3-receptor antagonists Antifungal drugs Antihistamines (H1-receptor antagonists) Antimotility drugs Antimuscarinics, bronchodilators Antimuscarinics, cardiovascular and gastrointestinal uses Antimuscarinics, genitourinary uses Antipsychotics, first-generation (typical) Antipsychotics, second-generation (atypical) Antiviral drugs Antiplatelet drugs, ADP-receptor antagonists Antiplatelet drugs, aspirin Azathioprine ß-blockers ß2-agonists Benzodiazepines Bisphosphonates Calcium and vitamin D Calcium channel blockers Carbamazepine Cephalosporins and carbapenems Chloramphenicol Corticosteroids (glucocorticoids), inhaled Corticosteroids (glucocorticoids), systemic Corticosteroids (glucocorticoids), topical Digoxin Dipeptidylpeptidase-4 inhibitors Direct oral anticoagulants Diuretics, loop Diuretics, thiazide and thiazide-like Dopaminergic drugs for Parkinson's disease Emollients Fibrinolytic drugs Gabapentin and pregabalin H2-receptor antagonists Heparins and fondaparinux Insulin Iron Lamotrigine Laxatives, osmotic Laxatives, stimulant Leukotriene receptor antagonists Levetiracetam Lidocaine Macrolides Metformin Methotrexate Metronidazole Naloxone Nicotine replacement and related drugs Nitrates Nitrofurantoin Non-steroidal antiinflammatory drugs Ocular lubricants (artificial tears) Oestrogens and progestogens Opioids, strong Opioids, weak/moderate Oxygen Paracetamol Penicillins Penicillins, antipseudomonal Penicillins, broad-spectrum Penicillins, penicillinase-resistant Phosphodiesterase (type 5) inhibitors Prostaglandin analogue eye drops Proton pump inhibitors Quinine Quinolones Serotonin 5-HT1-receptor agonists Sex hormone antagonists for breast cancer Statins Sulphonylureas Tetracyclines Thyroid hormones Trimethoprim Valproate (valproic acid) Vancomycin Vitamins Warfarin Z-drugs Fluids Colloids (plasma substitutes) Compound sodium lactate (Hartmann's solution) Glucose (dextrose) Potassium chloride Sodium chloride Self-assessment and knowledge integration 100 single best-answer questions Answers and explanations Index

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'I do not know much about God and prayer, but I have come to believe, over the last twenty-five years, that there's something to be said about keeping prayer simple. Help. Thanks. Wow.' Readers of all ages have followed and cherished Anne Lamott's funny and perceptive writing about faith and prayer. And in Help, Thanks, Wow, she has coalesced everything she's learned about prayer into these simple, transformative truths.It is these three prayers - asking for assistance, appreciating the good we witness, and feeling awe at the world - that get us through the day and show us the way forward. In Help, Thanks, Wow, Lamott recounts how she came to these insights, explains what they have meant to her over the years and how they've helped, and explores how others have embraced these ideas.Insightful and honest as only Anne Lamott can be, Help, Thanks, Wow is a book that new Lamott readers will love and longtime Lamott fans will treasure.

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Book SynopsisWith over 400 million Bibles in print, the New International Version is the world''s most popular modern English Bible. It is renowned for its combination of reliability and readability. Fully revised and updated for the first time in 25 years, the NIV is ideal for personal reading, public teaching and group study.This Bible also features: - clear, readable 6.75pt text- easy-to-read layout - shortcuts to key stories, events and people of the Bible - reading plan - timeline - book by book overview - quick links to find inspiration and help from the Bible in different life situationsThis edition uses British spelling, punctuation and grammar to allow the Bible to be read more naturally.More about the translationThis revised and updated edition of the NIV includes three main types of change, taking into account changes in the way we use language day to day; advances in biblical scholarship and understanding; and the need to ensure

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Book SynopsisAlongside practical advice on managing clinical and legal situations, the handbook provides concise examples, summaries of relevant legislation, and introductions to different ethical approaches and clinical observations. Uniquely focusing on the interface between psychiatry and law, this title is essential reading for the forensic psychiatrist.Trade ReviewReview from previous edition A careful reading of [Forensic Psychiatry's] content will enable the practitioner to progress unscathed through this minefield of conflicting paradigms and constructs. Encyclopaedic in its scope, thorough and fair-minded in its analysis, it sets the standard against which other texts in its field will be judged in the future. * Connor Duggan, Emeritus Professor of Forensic Mental Health, University of Nottingham *This is a wonderful book ... I wish it had been available when I started my training in forensic psychiatry ... every forensic psychiatry trainee (and many others besides) should own a copy. * Clare Oakley, Institute of Psychiatry, King’s College London, review in The Psychiatrist *This book is well-written, organized, informative, and was created for efficient use as a pocket guide. Although some of the information is limited to the UK and Ireland, there is plenty of knowledge for readers outside of these locations to learn about the field of forensic psychiatry. The book does this well without cluttering; it is easy to efficiently find and summarize information. The book is too large to fit truly in a pocket but small enough to easily carry around. * Andre Lars Lorenz, DO, St. Mary Mercy Hospital *Table of ContentsPart I: Introduction to the handbook 1: Introduction to the handbook Part II: Clinical forensic psychiatry 2: Clinical and social aspects of crime 3: Mental disorders in forensic psychiatry 4: Assessment in forensic psychiatry 5: Risk assessment 6: Treatment 7: Risk management 8: Forensic psychiatric services Part III: The ethics of forensic psychiatry 9: Ethical decision making 10: Professional duties and personal integrity 11: Conflicting ethical values 12: Clinical matters raising ethical issues Part IV: Law relevant to psychiatry 13: The interface between psychiatry and law 14: Legal systems 15: Criminal law 16: Mental health and mental capacity law 17: Civil law Part V: Psychiatry within the legal system 18: The criminal justice system 19: Legal tests relevant to psychiatry 20: The psychiatrist in court 21: Applied ethics and testimony 22: Providing reports 23: Giving evidence Part VI: Appendices A: Appendices

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Book SynopsisThis classic well-illustrated textbook simplifies neuroscience content to focus coverage on the essentials and helps students learn important neuroanatomical facts and definitions. Among its many distinctions are its organization by region and then pathways into and out of the nervous system, which permits students an integrated view of the anatomy and physiology; level of treatment suited to increasingly shorter neuroanatomy course hours for medical and allied health students; and the author''s succinct writing style.Table of ContentsPART I Introduction and Neurohistology1 Development, Composition, and Evolution of the Nervous System 2 Cells of the Nervous System3 Peripheral Nervous System 4 Imaging Techniques and Neuroanatomical Research Methods PART II Regional Anatomy of the Central Nervous System5 Spinal Cord 6 Brain Stem: External Anatomy 7 Brain Stem: Nuclei and Tracts8 Cranial Nerves 9 Reticular Formation10 Cerebellum 11 Diencephalon12 Corpus Striatum 13 Topography of the Cerebral Hemispheres 14 Histology of the Cerebral Cortex 15 Functional Localization in the Cerebral Cortex16 Cerebral White Matter and Lateral Ventricles 17 Olfactory System 18 Limbic System: The Hippocampus and the Amygdala PART III Review of the Major Systems19 General Sensory Systems 20 Visual System21 Auditory System22 Vestibular System 23 Motor Systems24 Visceral InnervationPART IV Blood Supply and the Meninges25 Blood Supply of the Central Nervous System 26 Meninges and Cerebrospinal FluidGlossary of Neuroanatomical and Related TermsIndex

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Book SynopsisSleep disorders have a significant impact on a child’s physical, emotional, cognitive, and social development, and greatly affect the family, as well. Fortunately, today’s health care providers have highly effective medical and behavioral interventions at their disposal for treatment and prevention. A Clinical Guide to Pediatric Sleep: Diagnosis and Management of Sleep Problems, 3rd Edition, synthesizes current information on the assessment and treatment of sleep disorders in children and adolescents and gives you the practical tools you need to recognize, evaluate, and treat sleep issues. This state-of-the-art resource provides comprehensive, user-friendly guidance on pediatric sleep that will help you improve the lives of your patients and their families. Stay up to date with current information on the etiology, clinical assessment tools, and management of specific sleep disorders in children and adolescents. Quickly find the information you nee

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Book SynopsisSelected as a Doody's Core Title for 2022 and 2023! Now in a fully revised 4th Edition, Modern Epidemiology remains the gold standard text in this complex and evolving field, offering unparalleled, comprehensive coverage of the principles and methods of epidemiologic research. Featuring a new, full-color design, updated models, and a new format allowing space for margin notes, this edition continues to provide authoritative information on the methodologic issues crucial to the wide range of epidemiologic applications in public health and medicine. Reflects both the conceptual development of this evolving science and the increasing role that epidemiology plays in both public health and medicine. Features a new full-color design, new coverage of marginal structural models, new instrumental variable analysis, updated structural nested models, and more. Covers a broad range of concepts and methods, including epi

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Book Synopsis Since the original publication of this seminal work, acceptance and commitment therapy (ACT) has come into its own as a widely practiced approach to helping people change. This book provides the definitive statement of ACT--from conceptual and empirical foundations to clinical techniques--written by its originators. ACT is based on the idea that psychological rigidity is a root cause of a wide range of clinical problems. The authors describe effective, innovative ways to cultivate psychological flexibility by detecting and targeting six key processes: defusion, acceptance, attention to the present moment, self-awareness, values, and committed action. Sample therapeutic exercises and patient-therapist dialogues are integrated throughout. New to This Edition *Reflects tremendous advances in ACT clinical applications, theory building, and research. *Psychological flexibility is now the central organizing focus. *Expanded coverage of mindfulness, the therapeutic relTrade Review"A 'must read' for everyone in the field of psychotherapy or behavior therapy, as well as students entering the profession. The significantly revised second edition reviews the growing body of research support for ACT and presents new developments in case conceptualization and treatment implementation."--David H. Barlow, PhD, ABPP, Professor Emeritus of Psychology and Psychiatry and Founder, Center for Anxiety and Related Disorders, Boston University "Acceptance and Commitment Therapy, Second Edition, presents new data and clinical insights and expresses the theoretical foundations of ACT in a fresh way. The original book was an extraordinary achievement; the second edition is even better. It shows exactly how basic science and therapeutic application can combine in the service of new and effective methods to alleviate suffering. This book is essential reading for all students and practitioners in clinical psychology, counseling, and psychiatry."--Mark Williams, DPhil, Emeritus Professor of Clinical Psychology, University of Oxford, United Kingdom "Presents an influential approach to helping clients accept their thoughts and feelings and overcome experiential avoidance....The authors delineate a solid clinical rationale and provide clear guidelines for ACT implementation. A real strength of this book is the chapters on each stage of treatment, which detail a wealth of strategies and interventions and include excellent exercises, therapist-client dialogues, and pointers for practice."--Leslie S. Greenberg, PhD, Distinguished Research Professor Emeritus of Psychology, York University, Canada "In the dynamic field of mindfulness-based therapies, this impressive book is a landmark contribution. The authors offer a sophisticated and wise approach to human transformation, one that has been validated by clinical research and honed by a wide range of clinical applications. This second edition is ideally suited for graduate-level courses in psychotherapy as well as for mental health practitioners. It offers a balance of rich theoretical context and clear, accessible guidance for applying ACT to a range of emotional and behavioral difficulties."--Tara Brach, PhD, author of Radical Acceptance "This second edition is perfectly timed, given the explosion of developments in the underlying theoretical principles and empirical research associated with this approach to treatment. The book is beautifully written and is an outstanding resource for clinicians and researchers alike, whether novice or experienced. The principles of functional contextualism and relational frame theory are laid out in an easily understandable yet in-depth manner. The book's presentation of the core principles of ACT--including practical guidance for implementing them in clinical practice--is simply superb. This is an excellent text for graduate students in clinical psychology."--Michelle G. Craske, PhD, Professor and Vice Chair of Psychology and Director, Anxiety Disorders Research Center, University of California, Los Angeles -Table of ContentsI. Foundations and the Model 1. The Dilemma of Human Suffering 2. The Foundations of ACT: Taking a Functional Contextual Approach 3. Psychological Flexibility as a Unified Model of Human Functioning II. Functional Analysis and Approach to Intervention 4. Case Formulation: Listening with ACT Ears, Seeing with ACT Eyes, with Emily K. Sandoz 5. The Therapeutic Relationship in ACT 6. Creating a Context for Change: Mind versus Experience III. Core Clinical Processes 7. Present-Moment Awareness, with Emily K. Sandoz 8. Dimensions of Self 9. Defusion 10. Acceptance 11. Connecting with Values 12. Committed Action IV. Building a Progressive Scientific Approach 13. Contextual Behavioral Science and the Future of ACT

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Book SynopsisMichael Hoffen is the youngest-ever recipient of the annual Emerson Prize, awarded by the Concord Review for outstanding promise in history. While still in middle school he was introduced to the joys of translating ancient texts and never looked back. During the pandemic, Michael decided to embark on an ambitious project to bring ancient Egyptian literature to life outside the classroom. Be A Scribe! is Michael's first book in a series intended for young readers. When not chasing down new stories to translate or write, Michael enjoys biking, swimming, and rock climbing. He lives with his family in New York. Dr. Christian Casey is an Egyptologist who specializes in the study of ancient Egyptian languages. He obtained his PhD in Egyptology from Brown University in 2020 and now works as a researcher at Freie Universität Berlin. He is especially interested in sharing the exciting world of ancient Egypt with young people and other interested members of the public. <

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Book Synopsis

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Book SynopsisJames Herriot grew up in Glasgow and qualified as a veterinary surgeon at Glasgow Veterinary College. Shortly afterwards he took up a position as an assistant in a North Yorkshire practice where he remained, with the exception of his wartime service in the RAF, until his death in 1995. He wrote many books about Yorkshire country life, including some for children, but he is best known for his memoirs, beginning with If Only They Could Talk. The books were televised in the enormously popular series All Creatures Great and Small.

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Book SynopsisAninspiring, 100% plant-based cookbookto help manage diabetes, prevent complications, and promote optimal healthwith easy vegan recipes, advice on meal planning, cooking tips,shopping lists, and more! Celebrated vegan nutritionist Sharon Palmer, aka The Plant-Powered Dietitian, presents 100 plant-based diet recipes for evidence-based diabetes management. Although there are many cookbooks tailored for people with diabetes, the vegan cookbook for diabetics is rare a surprising fact given mounting research proving plant-based diets have lasting benefits for people living with diabetes. Nearly 12% of the U.S. population has diabetes, while 38% of adults have prediabetesand it is our aging generation that carries the heaviest disease burden; roughly half of seniors in the U.S. have prediabetes. This book is especially for them. Sharon explains this research in an accessible and persuasive way with easy-to-understand graphs and charts, but also with a warm and friendly tone that will encoTrade Review“A must-buy for library cookbook collections.” —Library Journal “Going vegan has been proved to help prevent and treat type 2 diabetes, and this cookbook is full of recipes that can help manage diabetes and promote general health.” —PETA.org

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Book SynopsisThis book offers a framework for collaboration between art museum educators and health professionals. It includes advice on selecting meaningful and provocative works of art; models of responsive workshop design, compelling descriptions of gallery experiences; and references to supporting medical literature

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Book SynopsisIn her first spiritual book since DANCE WHILE YOU CAN and GOING WITHIN, the bestselling author and legendary actress recounts her pilgrimage along the Camino de Santiago de Compostela in northern Spain.

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Book Synopsis***This paperback edition has a new introduction by the author and updated content.This is the second volume of North Atlantic Books’ updated paperback edition of Dale Pendell’s Pharmako trilogy, an encyclopedic study of the history and uses of psychoactive plants and related synthetics first published between 1995 and 2005. The books form an interrelated suite of works that provide the reader with a unique, reliable, and often personal immersion in this medically, culturally, and spiritually fascinating subject. All three books are beautifully designed and illustrated, and are written with unparalleled authority, erudition, playfulness, and range.Pharmako/Dynamis: Stimulating Plants, Potions, and Herbcraft includes a new introduction by the author and as in previous editions focuses on stimulants (including coffee, tea, chocolate, and coca and its derivatives) and empathogens (notably Ecstasy). Each substance is explored in detail, not only with information on its history, pharmacology, preparation, and cultural and esoteric correspondences, but also the subtleties of each plant’s effect on consciousness in a way that only poets can do. The whole concoction is sprinkled with abundant quotations from famous writers, creating a literary brew as intoxicating as its subject. The Pharmako series also includes Pharmako/Poeia (which covers tobacco, alcohol, cannabis, opiates, salvia divinorum, and other substances) and Pharmako/Gnosis (which addresses psychedelics and shamanic plants).

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