Computational biology / bioinformatics Books
World Scientific Publishing Co Pte Ltd Chromatin And Gene Function: A Primer
Book SynopsisThe purpose of this primer is to provide students, teachers as well as academic and industry researchers with a succinct account of the chemical and structural features of chromatin and the role that these features play in the maintenance and function of the genetic material.It is universally accepted that DNA is the carrier of the genetic information that is transmitted from parents to their offspring and that it is responsible for the anatomy, physiology and behavior of all individuals throughout development and adult life. Yet, how this information is retrieved and used selectively to allow a fertilized egg to become an organism made up of myriads of different cells and tissues is not as evident and easily understood.Dr Lucchesi, an internationally known researcher and teacher, provides an easily opened window into the role that the complex of proteins and nucleic acids that are associated with the DNA play in mediating gene expression and in responding to environmental circumstances.
£42.75
World Scientific Publishing Co Pte Ltd Biocomputing 2023 - Proceedings Of The Pacific
Book SynopsisThe Pacific Symposium on Biocomputing (PSB) 2023 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2023 will be held on January 3-7, 2023 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2023 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's 'hot topics.' In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.
£157.50
World Scientific Publishing Co Pte Ltd Biocomputing 2024 - Proceedings Of The Pacific
Book SynopsisThe Pacific Symposium on Biocomputing (PSB) 2024 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2024 will be held on January 3 - 7, 2024 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2024 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's 'hot topics.' In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.
£162.00
Springer Verlag, Singapore Diversity and Evolution of Butterfly Wing Patterns: An Integrative Approach
Book SynopsisThis book facilitates an integrative understanding of the development, genetics and evolution of butterfly wing patterns. To develop a deep and realistic understanding of the diversity and evolution of butterfly wing patterns, it is essential and necessary to approach the problem from various kinds of key research fields such as “evo-devo,” “eco-devo,” ”developmental genetics,” “ecology and adaptation,” “food plants,” and “theoretical modeling.” The past decade-and-a-half has seen a veritable revolution in our understanding of the development, genetics and evolution of butterfly wing patterns. In addition, studies of how environmental and climatic factors affect the expression of color patterns has led to increasingly deeper understanding of the pervasiveness and underlying mechanisms of phenotypic plasticity. In recognition of the great progress in research on the biology, an international meeting titled “Integrative Approach to Understanding the Diversity of Butterfly Wing Patterns (IABP-2016)” was held at Chubu University, Japan in August 2016. This book consists of selected contributions from the meeting. Authors include main active researchers of new findings of corresponding genes as well as world leaders in both experimental and theoretical approaches to wing color patterns. The book provides excellent case studies for graduate and undergraduate classes in evolution, genetics/genomics, developmental biology, ecology, biochemistry, and also theoretical biology, opening the door to a new era in the integrative approach to the analysis of biological problems.This book is open access under a CC BY 4.0 license.Table of Contents
£40.49
Springer Verlag, Singapore Life Sciences Industry: From Laboratories to
Book SynopsisBasic principles of applied life sciences such as recombinant DNA technology is used in most life sciences industries marketing bio-formulations for designing more effective protein-based drugs, such as erythropoietin and fast-acting insulin etc. In recent times genetically engineered host cells from mammal, animal and plants are also being used in life sciences industries to manufacture biologics. This book discusses the most basic as well advanced issues on biological products for successfully managing a life sciences industry. It elucidates the life cycle of biological molecules, right from the conceptual development of different types of biopolymers, and their subsequent transfer from the conical flasks in laboratory to life sciences industries for large scale production and marketing. It focuses on sustainable longevity in the life cycle of commercial biopolymers. Cumulative facts and figures in this volume would immensely help in inspiring life sciences industry promoters to monitor value chain transfer process of biologics for better profitability. Additionally, it would serve as a perusal document for the students and researchers interested in entrepreneurial ventures or having their own start-up projects for the commercialization of biologics. Table of ContentsChapter 1. Prelusion Significance of Livestock.- Chapter 2. Mass Balance concept in Livestock Farming.- Chapter 3. Goat and Sheep Farming.- Chapter 4. Cattle and Buffaloes Farming.- Chapter 5. Factors Influencing Livestock Way of Life.- Chapter 6. Sustainable Livestock Farming.- Chapter 7. Conceptual Development of Livestock Supply Chain Management.
£161.99
Springer Verlag, Singapore Bioinformatics in Rice Research: Theories and
Book SynopsisThis book provides an up-to-date review of classic and advanced bioinformatics approaches and their utility in rice research. It summarizes databases and tools for analyzing DNA, proteins and gene expression profiles, mapping genetic variations, annotation of protein and RNA molecules, phylogenetic analysis, and pathway enrichment.In addition, it presents high-throughput technologies that are widely used to provide deep insights into the genetic architecture of important traits in the rice genome. The book subsequently discusses techniques for identifying RNA-protein, DNA-protein interactions, and molecular markers, including SNP and microsatellites, in the contexts of rice breeding and genetics.Lastly, it explores various tools that are used to identify and characterize non-coding RNA in rice and their potential role in rice research.Table of ContentsChapter 1_Introduction to Bioinformatics.- Chapter 2_Statistics for bioinformatics.- Chapter 3_ Introduction of the databases of rice.- Chapter 4_Brief insight into the evolutionary history and domestication of wild rice relatives.- Chapter 5_3000 Genome project- A brief insight.- Chapter 6_ Databases and bioinformatics tools for data mining .- Chapter 7_Sequence Alignment.- Chapter 8_Gene identification and structure Annotation.- Chapter 9_Phylogenetic Analysis.- Chapter 10_RNA Structure Prediction. -Chapter 11_Structural Proteomics.- Chapter 12_Gene ontology and pathway enrichment analysis.- Chapter 13_High throughput sequencing technologies.- Chapter 14_Mapping algorithms in high-throughput sequencing.- Chapter 15_DNA–Protein Interaction Analysis (ChIP-Seq).- Chapter 16_RNA–Protein Interaction Analysis.- Chapter 17_SNP Identification and Discovery.- Chapter 18_Microsatellite Markers from whole genome and Transcriptomic Sequences. - Chapter 19_Genome-wide association study.- Chapter 20_Expression Profiling and Discovery of microRNA.- Chapter 21_Computational approaches in identifying long non-coding RNA.- Chapter 22_circRNA in rice.- Chapter 23_ Metagenomics.- Chapter 24_RNA-Induced Gene Silencing.- Chapter 25_Single-cell RNA sequencing technologies.- Chapter 26_Recent Advancement in NGS Technologies.
£179.99
Springer Verlag, Singapore Quantitative Biology: A Practical Introduction
Book SynopsisThis textbook is for biologists, to conduct quantitative analysis and modeling of biological processes at molecular and cellular levels. Focusing on practical concepts and techniques for everyday research, this text will enable beginners, both students and established biologists, to take the first step in quantitative biology. It also provides step-by-step tutorials to run various sample programs in one’s personal computer using Excel and Python. This volume traces topics, starting with an introductory chapter, such as modeling, construction and execution of numerical models, and key concepts in quantitative biology: feedback regulations, fluctuations and randomness, and statistical analyses. It also provide sample codes with guidance to procedure programming for actual biological processes such as movement of the nucleus within a cell, cell-cycle regulation, stripe pattern formation of skins, and distribution of energy. Written by a leading research scientist who has a background in biology, studied quantitative approaches by himself, and teaches quantitative biology at several universities, this textbook broadens quantitative approaches for biologists who do not have a strong background in mathematics, physics, or computer programming, and helps them progress further in their research.Table of ContentsChapter 1: Introduction to Quantitative Biology.- Chapter 2: Architectonics of the Cell.- Chapter 3: Mechanics of the Cell.- Chapter 4: Implementing Toy Models in Microsoft Excel.- Chapter 5: Implementing Toy Models in Python.- Chapter 6: Differential Equations to Describe Temporal Changes.- Chapter 7: Diversity of the Cell.- Chapter 8: Randomness, diffusion, and probability.- Chapter 9: Self-Organization of the Cell.- Chapter 10: Modeling feedback regulations Chapter 11: Development of the Cell over Time (Perspectives).
£53.99
Springer Verlag, Singapore Pharmacokinetics: Basics to Applications
Book SynopsisThis textbook covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents mathematical techniques, step- by-step descriptive equations, and applicable statistical analysis methods for the easy understanding of the topic. Further, it covers the preclinical applications and methods of pharmacokinetic aspects. The book also contains mathematical problems and questions related to pharmacokinetics for students. Special emphasis is on recent pharmacokinetic methods and their applications for managing clinical data and biostatistical approaches based on the current literature. This book is primarily meant for researchers and students from academic institutions and to R&D professionals.Table of ContentsChapter 1: Fundamentals of Pharmacokinetics.- Chapter 2: Drug absorption.- Chapter 3: The extent of drug absorption: bioavailability, clearance, bioequivalence, and protein-binding.- Chapter 4: Pharmacokinetic models and drug distribution.- Chapter 5: Drug metabolism .- Chapter 6: Drug elimination and nonlinear kinetics.- Chapter 7: Pharmacokinetic drug-drug interactions.- Chapter 8: Pharmacokinetic applications.- Chapter 9: Pharmacokinetic sample collection and processing.- Chapter 10: Important bio-analytical instrumental techniques in pharmacokinetics.- Chapter 11: Statistics in pharmacokinetics.- Chapter 12: Pharmacokinetic software and tools.- Chapter 13: Pharmacokinetic laboratory-based experiments.- Chapter 14: Pharmacokinetic numerical problems with solutions.- Chapter 15: Questions, and questions & answers for practice.
£75.99
Springer Verlag, Singapore Pharmacokinetics: Basics to Applications
Book SynopsisThis textbook covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents mathematical techniques, step- by-step descriptive equations, and applicable statistical analysis methods for the easy understanding of the topic. Further, it covers the preclinical applications and methods of pharmacokinetic aspects. The book also contains mathematical problems and questions related to pharmacokinetics for students. Special emphasis is on recent pharmacokinetic methods and their applications for managing clinical data and biostatistical approaches based on the current literature. This book is primarily meant for researchers and students from academic institutions and to R&D professionals.Table of ContentsChapter 1: Fundamentals of Pharmacokinetics.- Chapter 2: Drug absorption.- Chapter 3: The extent of drug absorption: bioavailability, clearance, bioequivalence, and protein-binding.- Chapter 4: Pharmacokinetic models and drug distribution.- Chapter 5: Drug metabolism .- Chapter 6: Drug elimination and nonlinear kinetics.- Chapter 7: Pharmacokinetic drug-drug interactions.- Chapter 8: Pharmacokinetic applications.- Chapter 9: Pharmacokinetic sample collection and processing.- Chapter 10: Important bio-analytical instrumental techniques in pharmacokinetics.- Chapter 11: Statistics in pharmacokinetics.- Chapter 12: Pharmacokinetic software and tools.- Chapter 13: Pharmacokinetic laboratory-based experiments.- Chapter 14: Pharmacokinetic numerical problems with solutions.- Chapter 15: Questions, and questions & answers for practice.
£52.24
Springer Verlag, Singapore Handbook of DNA Forensic Applications and
Book SynopsisThis handbook covers tested and proven DNA forensic testing methodologies, forensic bioinformatics techniques, case studies and current forensic legal framework for investigation of variety of crimes and provides a clinching evidence for speedy justice. DNA testing is widely used for forensic purposes and is changing the paradigm of (crime) investigation. The book contains chapters on usage of ultramodern DNA collection kits, presents era evidence collection and preservation, high-end DNA sample analysis in laboratory, DNA legislation, expert evidences, challenging and successful case studies, data generation and application of AI and IoT techniques for DNA data analysis, DNA databanks and training manpower to facilitate timely reporting to the requesting agencies. This handbook equips and enables police, investigators and crime analysis laboratories with knowhow of high-end tools, procedures and techniques to link or exclude a criminal to a crime. It is expected that this will be used by first responders, police, forensic analysts, judiciaries, evidence handlers and students and scholars of criminology and forensic sciences worldwide. The intention to write this handbook is to make DNA technology and its importance reach every common man and professional for correctly using it as a tool as and when required. This is quite evident that awareness of DNA technology has increased at a reasonable pace. Courts and investigating agencies are convinced and confident with its accuracy, reliability and unmatched peace delivered by various techniques of DNA fingerprinting and DNA profiling.Table of ContentsThe Master Molecule in Witness Box (With some Case Studies) Collection, Preservation, retention, safety and Handling of DNA Evidences Chain of Custody – Dos and Don’ts Extraction and Analysis of DNA Samples in Laboratory Handling Mixed DNA Samples with the help of Forensic Bioinformatics Maintaining Standards and Calibration of DNA Testing Equipment DNA Based Identification in Mass Disaster Cases Using DNA Technologies in Sexual Offenses DNA Legislations – Challenges and Opportunities Developing DNA Databases and revolutionizing the Forensic Investigation Modernization of Police DNA Forensics Wing DNA Forensic Trainings for Police and Law enforcement Agencies Next Generation Technologies – Forensic Bioinformatics, LIMS, RFID, Biometrics, AI and IOT in modernising Crime Laboratories. Rapid DNA Identification and Best Practices
£134.99
Springer Verlag, Singapore Proceedings of International Conference on
Book SynopsisThis book gathers outstanding research papers presented at the 2nd International Conference on Frontiers in Computing and Systems (COMSYS 2021), organized by Department of Electronics and Communication Engineering and Department of Information Technology, North-Eastern Hill University, Shillong, Meghalaya, India held during September 29–October 1, 2021. The book presents the latest research and results in various fields of machine learning, computational intelligence, VLSI, networks and systems, computational biology, and security, making it a rich source of reference material for academia and industry alike.Table of ContentsExperimental Face Recognition System using Deep Learning Approaches.- MultiNet: A Diffusion based Approach to Assign Directionality in Protein Interactions using a Consensus of Eight Protein Interaction Datasets.- An Irrigation Support System Using Regressor Assembly.- Does Random Hopping Ensure More Pandal Visits than Planned Pandal Hopping?.- Consensus-based Identification and Comparative Analysis of Structural Variants and their Influence on 3D Genome Structure using Long- and Short-read Sequencing Technologies in Polish Families.- On the Performance of Convolutional Neural Networks with Resizing and Padding.- Analysis of Vegetation Health of the Sundarbans Region using Remote Sensing Methods.- You Reap What You Sow - Revisiting Intra-class Variations and Seed Selection in Temporal Ensembling for Image Classification.- Light U-Net: Network Architecture for Outdoor Scene Semantic Segmentation.- Framework of Intelligent Transportation System: A Survey.
£179.99
Springer Verlag, Singapore Lateral Asymmetry in Animals: Predator-Prey
Book SynopsisThis book presents the latest research findings on the laterality of fish and other animals. It describes all aspects of lateral asymmetry, including ecology, morphology, behaviour, dynamics of lefty and righty morphs, genetics and evolution, through field observations, experiments and modeling. Lateral asymmetry in scale-eating cichlids gives a simple and beautiful example of negative frequency-dependent selection and resulting oscillation of lefty and righty morph frequencies. Lateral dimorphism is found not only in scale-eaters but in all orders of fish, shrimps and cuttlefish. Lateral asymmetry interacts between species through "cross-predation." Contrary to fish, lateral asymmetry in snails acts as, in most cases, positive frequency-dependent selection and provides deep insights into speciation. Especially, snakes eating righty snails facilitate speciation of lefty snails.As a collaboration work of field ecologists and theoretical biologists, this book covers a variety of topics on lateral asymmetry, which are consistently related to predation. The topics include behavioral ecology, population dynamics, physiology, evolution, genetics, development, learning and neuroscience, statistics, with the subjects of fish, shrimp, prawn, and crayfish, crab, cuttlefish, and snake and snail. Chapters cover new research results such as cuttlefish laterality dynamics, interaction between laterality of snails and snakes, evolution of laterality genetic system, and statistical analysis of laterality oscillation. Readers will appreciate the simplicity and beauty of lateral asymmetry and its profound impact on ecology and evolution.Table of ContentsChapter 1. Laterality of Fish – Anti-symmetry in Fish Populations Maintained by the Interspecific Interaction.- Chapter 2. Universality of laterality among fish and invertebrates in aquatic communities.- Chapter 3.Predominance of Cross Predation or Parallel Predation in Fish.- Chapter 4.Behavioral laterality in the scale-eating cichlid fish: detailed movement, development, and neuronal mechanisms.- Chapter 5.Models of Lateral Asymmetry Dynamics:Realistic Oscillations by Time Delay andFrequency Dependence.- Chapter 6.Mathematical models of predators and prey with laterality.- Chapter 7.Statistical Analysis of Lateral Asymmetry:Detect Antisymmetry and Oscillation fromUnequal-Interval Binomial Data.- Chapter 8.Models of Genetic System of LateralAsymmetry: Population Dynamics DriveEvolution of Genetic System.- Chapter 9.Mechanisms Underlying Variations in the Dentition Asymmetry of Asian Snail-Eating Snakes.- Chapter 10.Single-gene speciation, balanced polymorphism, and antagonistic coevolution in left-right asymmetry of land snails.
£125.99
Springer Verlag, Singapore Mathematical and Computational Intelligence to
Book SynopsisThis book presents a collection of selected papers presented at the 22nd FAI International Conference on Mathematical, Computational Intelligence and Engineering Approaches to Healthcare, Business and Tourism Analytics (FAI-ICMCIE 2020), held at American College, Madurai, India, from 20–22 December 2020. This book discusses advanced mathematical concepts and computational intelligence approaches for: medical diagnostic approach in cardiac diseases, nano topology in medical diseases, stability of indicators in assessing business development, AI-guided paradigmatic competence in science and spirituality integration, neural network-TOPSIS analytics in hotel service quality, itinerary planning destination ranking tourism analytics, molecular modeling and docking simulation for unraveling medicinal properties, value-oriented approach on commercial banks security, Brownian motion in shares of the bank, internet of things linking to social media and e-commerce, and more, which are discussed by using fuzzy analytics, nano-topology, statistical, TOPSIS and neural network tools.Table of ContentsA Study on Medical Diagnostic Approach to Investigate Cardiac Diseases.- Economic and Mathematical Methods for Classifying the Stability of Indicators in Assessing Business Development.- Nano Topological Reductions of Attributes in Medical Diagnosis.- AI-Guided Paradigmatic Competence to Embrace Future Trends and Research: A Science-Spirituality Contribution.- Itinerary Planning Destination Ranking Tourism Analytics System.- Generalized Unitary Convolution, Ramanujan Sums and Applications.- A Class of the Extended Multi-Index Bessel-Maitland Functions and It’s Properties.- A Numerical Study on Atangana-Baleanu and Caputo-Fabrizio Fractional Derivatives for MHD Flow Past an Impulsively Started Vertical Plate with Ramped Temperature and Concentration with Viscous Dissipation.- Sufficient Conditions of q-Starlikeness and q-Convexity Associated with Basic Hypergeometric Function.- A New Computing Techniques on Digital Nano Topology.- A New Notion of Mappings in Nano Topology.
£98.99
Springer Verlag, Singapore Getting Started in Mathematical Life Sciences:
Book SynopsisThis book helps the reader make use of the mathematical models of biological phenomena starting from the basics of programming and computer simulation. Computer simulations based on a mathematical model enable us to find a novel biological mechanism and predict an unknown biological phenomenon. Mathematical biology could further expand the progress of modern life sciences. Although many biologists are interested in mathematical biology, they do not have experience in mathematics and computer science. An educational course that combines biology, mathematics, and computer science is very rare to date. Published books for mathematical biology usually explain the theories of established mathematical models, but they do not provide a practical explanation for how to solve the differential equations included in the models, or to establish such a model that fits with a phenomenon of interest. MATLAB is an ideal programming platform for the beginners of computer science. This book starts from the very basics about how to write a programming code for MATLAB (or Octave), explains how to solve ordinary and partial differential equations, and how to apply mathematical models to various biological phenomena such as diabetes, infectious diseases, and heartbeats. Some of them are original models, newly developed for this book. Because MATLAB codes are embedded and explained throughout the book, it will be easy to catch up with the text. In the final chapter, the book focuses on the mathematical model of the proneural wave, a phenomenon that guarantees the sequential differentiation of neurons in the brain. This model was published as a paper from the author’s lab (Sato et al., PNAS 113, E5153, 2016), and was intensively explained in the book chapter “Notch Signaling in Embryology and Cancer”, published by Springer in 2020. This book provides the reader who has a biological background with invaluable opportunities to learn and practice mathematical biology.Table of Contents1. Preparation.- 2. Introduction to MATLAB programming .- 3. Simulating time variations in life phenomena.- 4. Simulating temporal and spatial changes in biological phenomena.
£44.99
World Scientific Publishing Co Pte Ltd Computational Biology And Genome Informatics
Book SynopsisThis book contains articles written by experts on a wide range of topics that are associated with the analysis and management of biological information at the molecular level. It contains chapters on RNA and protein structure analysis, DNA computing, sequence mapping, genome comparison, gene expression data mining, metabolic network modeling, and phyloinformatics.The important work of some representative researchers in bioinformatics is brought together for the first time in one volume. The topic is treated in depth and is related to, where applicable, other emerging technologies such as data mining and visualization. The goal of the book is to introduce readers to the principle techniques of bioinformatics in the hope that they will build on them to make new discoveries of their own.Table of ContentsExploring RNA Intermediate Conformations with the Massively Parallel Genetic Algorithm (B A Shapiro et al.); Introduction to Self-Assembling DNA Nanostructures for Computation and Nanofabrication (T H LaBean); Mapping Sequence to Rice FPC (C Soderlund et al.); Graph Theoretic Sequence Clustering Algorithms and Their Applications to Genome Comparison (S Kim); The Protein Information Resource for Functional Genomics and Proteomics (C H Wu); High-Grade Ore for Data Mining in 3d Structures (J S Richardson & D C Richardson); Protein Classification: A Geometric Hashing Approach (X Wang & J T L Wang); Interrelated Clustering: An Approach for Gene Expression Data Analysis (C Tang et al.); Creating Metabolic Network Models Using Text Mining and Expert Knowledge (J A Dickerson et al.); Phyloinformatics and Tree Networks (W H Piel).
£78.85
World Scientific Publishing Co Pte Ltd Advanced Analysis Of Gene Expression Microarray
Book SynopsisThis book focuses on the development and application of the latest advanced data mining, machine learning, and visualization techniques for the identification of interesting, significant, and novel patterns in gene expression microarray data.Biomedical researchers will find this book invaluable for learning the cutting-edge methods for analyzing gene expression microarray data. Specifically, the coverage includes the following state-of-the-art methods:• Gene-based analysis: the latest novel clustering algorithms to identify co-expressed genes and coherent patterns in gene expression microarray data sets• Sample-based analysis: supervised and unsupervised methods for the reduction of the gene dimensionality to select significant genes. A series of approaches to disease classification and discovery are also described• Pattern-based analysis: methods for ascertaining the relationship between (subsets of) genes and (subsets of) samples. Various novel pattern-based clustering algorithms to find the coherent patterns embedded in the sub-attribute spaces are discussed• Visualization tools: various methods for gene expression data visualization. The visualization process is intended to transform the gene expression data set from high-dimensional space into a more easily understood two- or three-dimensional space.
£76.95
World Scientific Publishing Co Pte Ltd Pooling Designs And Nonadaptive Group Testing:
Book SynopsisPooling designs have been widely used in various aspects of DNA sequencing. In biological applications, the well-studied mathematical problem called “group testing” shifts its focus to nonadaptive algorithms while the focus of traditional group testing is on sequential algorithms. Biological applications also bring forth new models not previously considered, such as the error-tolerant model, the complex model, and the inhibitor model. This book is the first attempt to collect all the significant research on pooling designs in one convenient place.The coverage includes many real biological applications such as clone library screening, contig sequencing, exon boundary finding and protein-protein interaction detecting and introduces the mathematics behind it.Table of Contentsd-Disjunct Matrices and d-Separable Matrices; Geometric and Algebraic Designs; Random Designs; Subset-Containment Designs; Array and Transversal Designs; The Complex Model; The Inhibitor Model; Contig Sequencing; Gene Detection.
£101.70
World Scientific Publishing Co Pte Ltd Dna Microarray Technology And Data Analysis In
Book SynopsisDNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology.Table of ContentsDNA Microarray Technique; Current Analytical Methods of DNA Microarray Data; Advantages and Disadvantages; Current Application of DNA Microarray Technique in Medicine; A Novel Method for DNA Microarray Data Analysis; Future Directions.
£76.95
World Scientific Publishing Co Pte Ltd Nanopore Sequencing: An Introduction
Book SynopsisThis is an introductory text and laboratory manual to be used primarily in undergraduate courses. It is also useful for graduate students and research scientists who require an introduction to the theory and methods of nanopore sequencing. The book has clear explanations of the principles of this emerging technology, together with instructional material written by experts that describes how to use a MinION nanopore instrument for sequencing in research or the classroom.At Harvard University the book serves as a textbook and lab manual for a university laboratory course designed to intensify the intellectual experience of incoming undergraduates while exploring biology as a field of concentration. Nanopore sequencing is an ideal topic as a path to encourage students about the range of courses they will take in Biology by pre-emptively addressing the complaint about having to take a course in Physics or Maths while majoring in Biology. The book addresses this complaint by concretely demonstrating the range of topics — from electricity to biochemistry, protein structure, molecular engineering, and informatics — that a student will have to master in subsequent courses if he or she is to become a scientist who truly understands what his or her biology instrument is measuring when investigating biological phenomena.
£85.50
World Scientific Publishing Co Pte Ltd Understand Your Dna: A Guide
Book SynopsisAre you considering to test your own DNA? Do you want to learn more about your health and ancestry? Understand your DNA — A Guide is about what you can use genetics for. For a few hundred dollars, you can now scan your own genes. Millions of people all over the world have already done so. Everyone wants to see what they can get to know about themselves, and the market growing rapidly. But what does it require from you? And what can you really use a DNA test for? Understand your DNA — A Guide helps you put the plots and charts of consumer genetics into perspective and enables you to figure out what's up and down in the media headlines. The book is also a key input for today's debate about what we as a society can and want to do with medical genetics. Genetics will play a growing role in the future. Understand your DNA — A Guide is an easy-to-read and necessary guide to that future. The book is provided with a foreword by Professor Sham Pak-Chung of Hong Kong University.While there are many books about genetics, they typically take the perspective of a scientist wanting to understand the molecular levels. At the same time, direct-to-consumer genetics is a booming market, with millions of people already tested. Very little has been published that will guide them for real, because the need here is more focused on medical and practical understanding, than focussed on molecules.This book therefore aims to hit that vacant spot in the market. It's a walk-through of all concepts that are necessary to understand in your own analysis. Meanwhile, it is also limited in scope to only those concepts — thus distinguishing it from broader works.The book is appropriate for the readerships in modern multi-ethnic metropolises because it mixes European and Asian examples, both from the collaboration between the author from Europe and the foreword-writer, Prof. Pak Sham of Hong Kong University. But also, because many of the examples in the book concerns differences and similarities between Asian and European ethnicities, something the author believes is a trend in time.Related Link(s)
£52.25
World Scientific Publishing Co Pte Ltd Pathological Specimens And Genomic Medicine:
Book SynopsisPathological Specimens and Genomic Medicine — Emerging Issues surveys various fields and medical disciplines related to the implementation of the new field of genomic medicine. The book includes sections on specimen processing, the effects of tissue fixation and storage impact on downstream molecular assays, image analysis and its role in the pathology workflow, molecular evaluation of samples, and how to present data to clinicians. The book contains examples of cases where these innovative technologies are applied in the real world, and also presents a look in to the future of the field of genomic medicine.
£121.50
Pan Stanford Publishing Pte Ltd Cap-Analysis Gene Expression (CAGE): The Science
Book SynopsisThis book is a guide for users of new technologies, as it includes accurately proven protocols, allowing readers to prepare their samples for experiments. Additionally, it is a guide for the bioinformatics tools that are available for the analysis of the obtained tags, including the design of the software, the sources and the Web. Finally, the book provides examples of the application of these technologies to identify promoters, annotate genomes, identify new RNAs and reconstruct models of transcriptional control. Although examples mainly concern mammalians, the discussion expands to other groups of eukaryotes, where these approaches are complementing genome sequencing.Trade Review"This is a comprehensive introduction to a powerful and important new technique that is transforming our understanding of gene regulation. This volume contains everything you need to know to become an expert in CAGE, from library construction to bioinformatic analysis of the voluminous data sets."—Gene E. Robinson, University of IllinoisTable of ContentsBrief Historical Perspective on Transcriptional Regulation. Preparation of CAGE Libraries: An Enabling Experimental Protocol. Ditags and PET-Technologies for Transcript Identification and Review Use of Ditags with Emphasis on Gene Identification. From Sequencing Output to CAGE Tags: A Chapter on the Extraction of CAGE Tags from the Raw Output of the Sequencing Machine. Using CAGE Data for Quantitative Expression. Compare CAGE Expression to Microarrays and qPCR. Identification of Isoforms. Promoter Analysis Databases. Construction and Tutorial of the CAGE Analysis Viewer and Genome Viewer. Transcriptional Network Analysis Using CAGE. Biological Examples of Alternative TSS/Promoters. Challenges in CAGE Analysis.
£108.00
World Scientific Publishing Co Pte Ltd Systems Biology: Applications In Cancer-related
Book SynopsisThis volume presents an overview of recent developments in systems biology and their applications in cancer-related research. The ongoing advances in our understanding of genomics and proteomics, coupled with the development of new and more robust tools, have led to an emphasis on analyzing biological systems at multiple levels. Thus, there is a need to integrate different types of data into a comprehensive “systems” view.Written by active researchers in the emerging areas, this book gives senior undergraduate students, graduate students and new researchers an idea of where the frontiers of systems biology are and an opportunity to learn high-throughput techniques in use. One of the particular emphases of the book is to elucidate the molecular mechanisms in cancer. The discovery of biomarkers and anti-cancer drugs using systems biology approach is also extensively discussed.Table of ContentsGene/Protein Networks and Pathways: Introduction to Systems Biology; Gene Network Construction for Molecular Regulation; MicroRNA Regulated Cellular Networks in Cancer; Disease-related Modules in Protein Interaction Networks; Biomolecular Pathway Modeling; High-throughput Omics Data and Analysis: Methods and Systems for ChIP-seq Data Analysis; Discovery of Transcription Factor Binding Sites and Its Applications in Cancer Study; Cancer Epigenomics; Tools and Emerging Applications for Mining the Phosphoproteome in Cancer Biology; Predicting Cancer-Related MicroRNAs; MicroRNA Regulation: Databases and Tools; Applications for Biomarkers and Drug Discovery: Next-Generation Sequencing Technologies and Their Applications in Cancer Research; Membrane Proteomics for the Opportunity of Cancer Biomarker and Drug Target Discovery; Structure-Based Systems Biology and Drug Design in Cancer Research; Discovering Drug Targets for Cancer
£94.50
World Scientific Publishing Co Pte Ltd Advances In Genomic Sequence Analysis And Pattern
Book SynopsisMapping the genomic landscapes is one of the most exciting frontiers of science. We have the opportunity to reverse engineer the blueprints and the control systems of living organisms. Computational tools are key enablers in the deciphering process. This book provides an in-depth presentation of some of the important computational biology approaches to genomic sequence analysis. The first section of the book discusses methods for discovering patterns in DNA and RNA. This is followed by the second section that reflects on methods in various ways, including performance, usage and paradigms.Table of ContentsPattern Discovery Methods: Large-Scale Gene Regulatory Motif Discovery with NestedMICA (M Piipari et al.); R'MES: A Tool to Find Motifs with a Significantly Unexpected Frequency in Biological Sequences (S Schbath & M Hoebeke); An Intricate Mosaic of Genomic Patterns at Mid-range Scale (A Fedorov & L Fedorova); Motif Finding from Chips to ChIPs (G Pavesi); A New Approach to the Discovery of RNA Structural Elements in the Human Genome (L Hua et al.); Performance and Paradigms: Benchmarking of Methods for Motif Discovery in DNA (K Klepper et al.); Encyclopedias of DNA elements for Plant Genomes (J Lichtenberg et al.); Manycore High-Performance Computing in Bioinformatics (J-S Varre et al.); Natural Selection and the Genome (A L Hughes).
£82.65
World Scientific Publishing Co Pte Ltd Biomolecular Forms And Functions: A Celebration
Book SynopsisUnderstanding the functions and properties of molecules in living systems requires a detailed knowledge of their three-dimensional structures and the conformational variability that allows them to adopt multiple functional forms. Interpreting biological systems in the language of three-dimensional structures is of fundamental importance and innumerable research groups around the world are working in this area. This book is a compilation of articles describing attempts at understanding the intricacies of biological systems through the structures of and interactions between their constituent molecules.
£148.50
