Cardiovascular medicine Books

Book SynopsisVascular surgery has seen a remarkable evolution. A discipline focused on the natural history and treatment of vascular disease by open operation is now primarily a minimally invasive specialty. Mastery of the basic pathophysiology has been retained while the transformation by improved imaging and endovascular intervention has been integrated into practice.This fourth edition of Vascular Surgery: Principles and Practice has incorporated these advances building on the specialty’s past assets. Knowledge of natural history and open surgery will always have an essential role in optimal care of patients with vascular diseases. The authors’ exposition of the old and the new will make this edition a valuable resource for vascular surgeons and all others dedicated to the care of vascular patients.Trade Review"In the final analysis, this book reflects the changes to vascular surgery all have witnessed in the last 50+ years,adhering to tried and true principles while adopting evidence-based medicine. It is an excellent reference for vascular surgeons in training and a worthy review book for established practitioners wishing to refresh their knowledge in areas on the periphery of their expertise."Gary W. Lemmon, MD, FACS Professor Vascular Surgery, Indiana University School of Medicine, Society for Vascular SurgeryTable of ContentsExposition of interventional methods. Vascular anatomy, techniques and complications associated with transplantation surgery. Extracranial vascular disease. Carotid artery stenting. Management of asymptomatic carotid artery disease.

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Book SynopsisAce the echocardiography boards with this unique review tool! Questions, Tricks, and Tips for the Echocardiography Boards provides one-of-a-kind assistance directly from those who have recently passed the exam – including hundreds of questions and video clips that mimic what you’re likely to encounter. The Second Edition also incorporates valuable feedback from Dr. Sorrell’s recent fellows, ensuring complete, up-to-date coverage of the information you need to know to perform at your best on the exam. Features 700+ questions and 350+ video clips with thorough explanations of both correct and incorrect answers, helping you place key concepts in the context of clinical practice. Includes a new chapter on how to accurately maneuver the transducer for particular views and make other adjustments, challenging you to go beyond mere book learning to a more complete understanding of optimal image acquisition. Incorporates questions related to

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Book SynopsisPulmonary Circulation provides physicians with a better understanding of the structure, function and pathophysiology of the pulmonary circulation. It provides comprehensive coverage from diagnosis and clinical evaluation of patients with pulmonary hypertension to imaging techniques, disorders and treatment.This new edition incorporates the latest clinical, pathophysiological and pathological research on pulmonary circulatory disorders. In particular, it provides greater emphasis on the role of the right ventricle in pulmonary vascular disease, updated knowledge on pathobiology and genetics, and includes new material related to imaging and other diagnostic modalities. This edition also reflects new classifications and all the recommendations from the 2013 World Conference on Pulmonary Circulation as well as current guidelines from the European Society of Cardiology and the European Respiratory Society.Thoroughly updated to keep up with the brisk Trade ReviewPraise for previous editions:"This book is at the vanguard of its type in the field of pulmonary circulation, and it achieves the editors' ambitious goal of providing a balance between scientific review and clinically relevant comprehensive guidelines for the busy practising physician."—New England Journal of MedicinePraise for previous editions:"This book is at the vanguard of its type in the field of pulmonary circulation, and it achieves the editors' ambitious goal of providing a balance between scientific review and clinically relevant comprehensive guidelines for the busy practising physician."—New England Journal of MedicineTable of ContentsPhysiology and Pathophysiology of Pulmonary Circulation and Right Heart. Pathobiology of Pulmonary Vascular Disease and Right Ventricular Failure. Clinical Assessment of Pulmonary Hypertension. Group 1: Pulmonary Arterial Hypertension. Drug and Nondrug Treatment of Group 1 Pulmonary Arterial Hypertension. Group 2: Pulmonary Hypertension Associated with Left Heart Conditions. Group 3: Pulmonary Hypertension Associated with Hypoxia, Hypoventilation, and Lung Disease. Group 4: Chronic Thromboembolic Pulmonary Hypertension. Pulmonary Hypertension with Unclear and/or Multifactorial Mechanisms. Acute Pulmonary Embolism. Pediatric Pulmonary Hypertension. Pulmonary Circulation In Critical Care. Pulmonary Circulation in Environmental Stress. Pulmonary Arterio-Venous Malformations and Shunts. Pulmonary Vascular Tumors and Pulmonary Vasculitis.

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Book SynopsisThis book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.Table of ContentsTable of ContentsSection 1: Introduction1.1- Early development of bioresorbable scaffoldPatrick W. SerruysSection 2: Principles of bioresorption, vascular application2.1- Degradable, biodegradable and bioresorbable polymers for time-limited therapyMichel Vert2.2- Lactic acid-based polymers in depthMichel Vert and Antoine Lafont2.3- Scaffold processingJack Scanlon2.4- Basics of biodegradation of magnesiumMichael Haude, Daniel Lootz, Hubertus Degen and Matthias Epple2.5- Basics of biodegradation of iron scaffoldDeyuan Zhang and Runlin GaoSection 3: From bench test to preclinical assessment3.1- Unlocking scaffold mechanical propertiesJack Scanlon, Yoshinobu Onuma, Patrick W. Serruys and Joseph Deitzel3.2- Bench testing for polymeric bioresorbable scaffoldsJohn A. Ormiston, Bruce Webber, Janarthanan Sathananthan, Pau Medran-Gracia, Susann Beier and Mark WI Webster3.3- Bench test for magnesium scaffoldDaniel Lootz, Wolfram Schmidt, Peter Behrens, Klaus-Peter Schmitz, Michael Haude and Ron Waksman3.4- Simulation of flow and shear stressNicolas Foin, Ryo Torii, Renick Darren Lee, Alessio Mattesini, Carlo Di Mario, Philip Wong, Erhan Tenekecioglu, Tom Crake, Christos Bourantas and Patrick W. Serruys3.5- Preclinical assessment of bioresorbable scaffolds and regulatory implicationTobias Koppara, Eric Wittchow, Renu Virmani and Michael JonerSection 4: Lesson learned from preclinical assessment4.1- PLA scaffoldKazuyuki Yahagi, Sho Torii, Erica Pacheco, Frank D. Kolodgie, Aloke V. Finn and Renu Virmani4.2- IronRunlin Gao, Deyuan Zhang, Hong Qiu, Chao Wu, Ying Xia and Gui ZhangSection 5: Imaging to evaluate the bioresorbable scaffold: A corelab perspective, methodology of measurement and assessment5.1- Quantative coronary angiography of bioresorbable vascular scaffold: a corelab perspectiveYohei Sotomi, Patrick W. Serruys and Yoshinobu Onuma5.2- Assessment of bioresorbable scaffolds by IVUS: echogenicity, virtual histology and palpographyCarlos M. Campos, Patrick W. Serruys and Hector M. Garcia-Garcia5.3- Optical coherence tomography analysis vascular scaffold in comparison with metallic stents: a corelab perspectiveYohei Sotomi, Pannipa Suwannasom, Jouke Dijkstra, Carlos Collet, Shimpei Nakatani, Patrick W. Serruys, Yoshinobu Onuma5.4- Non-invasive coronary tomography analysis after bioresorbable scaffold implantationCarlos Collet, Koen Nieman, Patrick W. Serruys and Yoshinobu Onuma5.5- Angiography is sufficientJ Ribamar Costa, Jr. and Alexandre Abizaid5.6- Intravascular ultrasound is a must in bioresorbable scaffold implantationHiroyoshi Kawamoto, Neil Ruparelia and Antonio Colombo5.7- OCT is the way to goJiang Ming Fam, Nienke Simone van Ditzhuijzen, Jors van Sjide, Bu Chan Zhang, Antonios Karanasos, Robert-Jan van Geuns and Evelyn Regar5.8- Imaging to evaluate the bioresorbable scaffold. Clinician’s perspective: I need both (IVUS and OCT)Josep Gomez-Lara and Antoni Serra5.9- Multislice computed tomography as a modality of follow-upAntonio L. Bartorelli, Daniele Andreini, Simona Espejo and Manuel PanSection 6: Clinical evidence of randomised and non-randomised trials: personal perspective6.1- What are appropriate clinical endpoints? From device failure assessment to angina evaluationMaik J. Grundeken, Yoshinobu Onuma and Patrick W. Serruys6.2- Angina reduction after BRS implantation: correlation with changes in coronary haemodynamicsNick E.J. West, Adam J. Brown and Stephen P. Hoole6.3- Comparison of everolimus eluting bioresorbable scaffolds with everolimus eluting metallic stents for treatment of coronary artery stenosis: Three-year follow-up of the Absorb II randomized trialCarlos Collet et al.6.4- The ABSORB China trialRunlin Gao6.5- ABSORB JapanTakeshi Kimura6.6- What have we learned from meta-analysis of 1 year outcomes with the Absorb bioresorbable scaffold in patients with coronary heart diseaseYohei Sotomi, Carlos Collet, Takeshi Kimura, Runlin Gao, Dean J. Kereiakes, Gregg W. Stone, Stephen G. Ellis, Yoshinobu Onuma and Patrick W. Serruys6.7- Summary of investigator-driven registries on absorb bioresorbable vascular scaffoldsAnna Franzone, Raffaele Piccolo and Stephen Windecker6.8- Investigator-driven randomised trialsDaniele Giacoppo, Roisin Colleran and Adnan Kastrati6.9- The DESolve scaffoldStefan Verheye, Nagarajan Ramesh, Lynn Morrison and Sara Toyloy6.10- Results of clinical trials with BIOTRONIK magnesium scaffoldsMichael Haude, Daniel Lootz, Raimund Erbel, Jacques Koolen and Ron Waksman6.11- The REVA medical program: from ReZolve® to Fantom®Alexandre Abizaid and J. Ribamar Costa Jr.6.12- The Amaranth’s bioresorbable vascular scaffold technologyAlaide Chieffo, Juan F. Granada and Antonio Colombo6.13- The mirage microfiber sirolimus eluting coronary scaffoldTeguh Santoso, Liew Houng Bang, Ricardo Costa, Daniel Chamié, Solomon Su, Alexandre Abizaid, Yoshinobu Onuma and Patrick W. Serruys6.14- The Igaki-Tamai stent: the legacy of the work of Hideo TamaiSoji Nishio, Kunihiko Kosuga, Eisho Kyo, Takafumi Tsuji, Masaharu Okada, Shinsaku Takeda, Yasutaka Inuzuka, Tatsuhiko Hata, Yuzo Takeuchi, Junya Seki and Shigeru IkeguchiSection 7: Clinical evidence in specific patient subsets: personal perspective7.1- Left main interventions with BRSBert Everaert, Piera Capranzano, Corrado Tamburino, Ashok Seth and Robert-Jan van Geuns7.2- Bioresorbable scaffolds in bifurcationsFilippo Fingini, Hiroyoshi Kawamoto and Azeem Latib7.3- BVS in chronic total occlusions: clinical evidence, tips and tricksAntonio Serra7.4- Bioresorbable scaffolds in diffuse diseaseNeil Ruparelia, Hiroyoshi Kawamoto and Antonio Colombo7.5- Bioresorbable scaffolds in mulitvessel coronary diseaseR.P. Kraak, Maik J. Grundeken and J.J Wykrzykowska7.6- Bioresorbable coronary scaffolds in non-St elevation acute coronary syndromesCharis Mamilou and Tommaso Gori7.7- Bioresorbable vascular scaffold in ST-segment elevation myocardial infarction: clinical evidence, tips and tricksGiuseppe Giacchi and Manel Sabaté7.8- Bioresorbable scaffolds for treating coronary artery disease in patients with diabetes mellitusAyyaz Sultan, Takeshi Muramatsu and Javaid Iqbal7.9- BRS in calcified lesionsAshok Seth7.10- BRS textbook: invasive sealing of vulnerable, high-risk lesionsChristos Bourantas, Ryo Torri, Nicolas Foin, Ajay Suri, Erhan Tenekecioglu, Vikas Thondapu, Tom Crake, Peter Barlis and Patrick W. SerruysSection 8: Complications (incidence, diagnosis, potential mechanisms and treatment)8.1- Acute and subacute scaffold thrombosisDavide Capodanno8.2- Late and very late scaffold thrombosisAntonios Karanasos, Bu-Chun Zhang, Jors van der Sijde, Jiang-Ming Fam, Robert-Jan van Geuns and Evelyn Regar8.3- Treatment of bioresorbable scaffold failureCordula M. Felix, Bert Everaert, Nigel Jepson, Corrado Tamburino and Robert-Jan van Geuns8.4- Recoil and bioresorbable scaffoldsJohn A. Ormiston, Bruce Webber, Janarthanan Sathananthan and Mark WI Webster8.5- Scaffold disruption and late discontinuitiesYoshinobu Onuma, Patrick W. Serruys8.6- The incidence, potential mechanism of side-branch occlusion after implantation of bioresorbable scaffold(s): insights from ABSORB IIYuki Ishibashi, Takeshi Muramatsu, Yohei Sotomi, Yoshinobu Onuma and Patrick W. SerruysSection 9: Tips and tricks to implant BRS9.1- Tips and tricks for implanting BRS: sizing, pre- and post-dilatationAkihito Tanaka, Richard J. Jabbour and Antonio Colombo9.2- Approach to bifurcation lesionsAshok SethSection 10: Emerging technologies (pre-CE mark, pre-FA, pre-PMDA and pre-CFDA)10.1- Overview of the fieldYoshinobu Onuma10.2- MeRes100™- a sirolimus eluting bioresorbable vascular scaffold systemAshok Seth, Babu Ezhumalai, Sanjeev Bhatt and Pratik Vasani10.3- XINSORB bioresorbable vascular scaffoldJunbo Ge and Li Shen10.4- NeoVas™ bioresorbable coronary scaffold systemHan Yangling10.5- ArterioSorb™ bioresorbable scaffold by Arterius LtdRasha Al-Lamee10.6- LifetechDeyuan Zhang, Wenjiao Lin, Haiping Oi10.7- Abbott: new generation absorb scaffoldLaura E. Leigh Perkins, Byron J. Lambert and Richard J. Rapoza

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Book SynopsisAuthored by the originator of the standard nomenclature for this spectrum of disorders, Congenital Heart Disease: A Clinical, Pathological, Embryological, and Segmental Analysis discusses the history, anatomic features, and physiologic consequences of CHD-in one authoritative resource. The Van Praagh approach to the segmental classification of CHD, developed and implemented by Dr. Richard Van Praagh in the 1960s at Boston Children's Hospital, remains widely used today, facilitating communication among radiologists, cardiologists, surgeons, and pediatricians who are involved in the diagnosis, characterization, and management of this disease. This unique atlas offers complete coverage of the ubiquitous Van Praagh "language” of CHD, including the signs, symptoms, and clinical manifestations of malpositioned, malformed, or absent cardiovascular chambers, vessels, and valves using traditional as well as state-of-the-art technology. Based upon the systematic, widely accepted Van Praagh system of three-part notation used to succinctly describe the visceroatrial situs, the orientation of the ventricular loop, and the position and relation of the great vessels. Demonstrates how the Van Praagh approach facilitates interpreting and reporting findings through cardiac imaging with CT, MR, and ultrasonography, including fetal cardiac imaging. Presents the pathologic anatomy that pediatric and adult cardiologists, radiologists, and echocardiographers need to understand in order to make accurate diagnoses in complex congenital heart disease; as well as the pathologic anatomy that interventionists, pediatric cardiac surgeons, and adult congenital heart surgeons need to know in order to manage their patients successfully. Features more than 550 high-quality images to help you visualize and recognize malformations. Shares the knowledge and expertise of a world-renowned authority on congenital heart disease-a master teacher and the originator of the Van Praagh segmental classification system. Explores the synergy between the various disciplines who manage patient care, including surgeons, radiologists, cardiologists, pathologists, and pediatricians. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.Table of ContentsHISTORICAL PERSPECTIVE Brief History of the Cardiovascular System CARDIOVASCULAR DEVELOPMENT Embryology and Etiology ANATOMIC AND DEVELOPMENTAL APPROACH TO DIAGNOSIS Morphologic Anatomy Segmental Anatomy CONGENITAL HEART DISEASE The Congenital Cardiac Pathology Database Systemic Venous Anomalies Pulmonary Venous Anomalies Cor Triatriatum Sinistrum (Subdivided Left Atrium) and Cor Triatriatum Dextrum (Subdivided Right Atrium) Interatrial Communications Juxtaposition of the Atrial Appendages Common Atrioventricular Canal Double-outlet and Common-outlet Right Atrium Tricuspid Valve Anomalies Mitral Valve Anomalies Infundibuloarterial Situs Equations: How Normally and Abnormally Related Great Arteries are Built and the Importance of Infundibuloarterial Situs Concordance and Discordance Ventricular Septal Defects Single Ventricle Superoinferior Ventricles Anomalous ifundibular Muscle Bundles Tetralogy of Fallot Absence of the Subpulmonary Infundibulum with its Sequelae has been Misinterpreted as Common Aortopulmonary Trunk that Probably Does Not Exist Transposition of the Great Arteries Double-Outlet Right Ventricle Double-Outlet Left Ventricle Anatomically Corrected Malposition of the Great Arteries What Prevents and What Permits the Embryonic Great Arterial Switch? Infundibulo-Arterial Situs Equations and Analysis The Cardiac Conduction System The Heterotxy Syndromes: Asplenia, Polysplenia, and with Normally Formed but Right-Sided Spleen

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Book SynopsisThe nanosciences are a rapidly expanding field of research with applicability to all areas of health and disease prevention, including cardiology in its broadest sense. This book covers a variety of nano subjects and areas as applied to the heart and circulatory system. There are state-of-the-art chapters on nanoparticles, nanowires, nanoscale topography, nanosensors, nanospheres, nanospin probes, nanomatrices and nanobubbles to name but a few topics. Their applications to cardiovascular disorders and their treatments are also described.Table of ContentsGeneral Methods and Applications: Nanoparticle Contrast Agents for Cardiovascular Medical Imaging. Cell Sheet Nanotechnology: Engineering and Applications to Cardiology. Nanowire Field-effect Transistors and their Applications to Cardiology. Atomic Force Microscopy and the Detection of Nanosized Blood Microparticles. Nanobiotechnology Based Blood Substitutes and the Cardiovascular Systems in Transfusion Medicine. Collagen Scaffolds and their Application to Cardiology—The Importance of Matrix Interactions and Nanoscale Topography. Cardiac Biomarker and Nano Wire Sensor Arrays. Electrical Recording from Cardiac Cells and Tissue using Nanowire Transistors. Nanospheres and Applications to Cardiology. Multifunctionality: The Key of Future Success. Nanomonitor Technology and its Applicability to Diagnosis of Cardiac Disease. Nanospin Probes and Applications to Cardiology. Native Endothelium Mimicking Nanomatrices and Applications. Nanofibre Based Vascular Grafts. Focused areas, treatments and diseases: Nanoparticle Processing of Cholesterol-Lowering Drug. Intratracheal Gene Transfer using Polyplex Nanomicelles and their Application to Cardiology. Use of Microbubbles and Nanobubbles for Diagnostic Vascular Molecular Imaging and Therapeutic Applications. Multifunctional Nanoagents for the Detection and Treatment of Thromboses. Biodegradable Nanofibers in Cardiovascular Medicine: Drug Delivery Application. Europium Hydroxide Nanorods and Angiogenic Processes. Iron Oxide Nano Particles and Cardiac Stem Cells. Nitric Oxide from Nanoparticles and Applications to Cardiovascular Health.

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Book SynopsisWith a step-by-step method for accurate interpretation of the ECG, this third edition of Rapid ECG Interpretation describes a systematic approach consistent with the changes in cardiology practice over the past decade. All diagnostic ECG criteria are given with relevant and instructive ECGs, providing a quick review or refresher for proficiency tests and for physicians preparing for the ECG section of the Cardiovascular Diseases Board Examination. This edition contains over 320 ECGs and instructive illustrations, including 81 new ECG tracings. Clear and concise 11-step methods are set out in a user-friendly synopsis format.Trade ReviewFrom the reviews of the third edition: "As the title indicates, the book describes a method of ECG interpretation meant to increase the reader’s accuracy and speed when reviewing ECGs. … It is aimed at anyone wanting to improve proficiency in ECG interpretation. It starts at a very basic level but provides information that would be useful to trainees in medicine and cardiology seeking to hone their skills. … This book provides a method for systematic interpretation of ECG suitable for beginning ECG readers." (James Schipper, Doody’s Review Service, January, 2008)Table of ContentsContents 1 Basic Concepts 1 2 Step-by-Step Method for Accurate ECG Interpretation 3 P Wave Abnormalities 4 Bundle Branch Block 5 ST Segment Abnormalities 6 Q Wave Abnormalities 7 Atrial and Ventricular Hypertrophy 8 T Wave Abnormalities 9 Electrical Axis and Fascicular Block 10 Miscellaneous Conditions 11 Arrhythmias 12. ECG Board Asessment Quiz

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Book SynopsisThe study of valvular heart disease has progressed rapidly over the past two decades. The understanding of etiology and natural history, the precision of noninvasive assessment, and the surgical and interventional management of valve disease have all improved dramatically. Coupled with an appreciation of physiologic principles, thoughtful interviews and physical exam, current technology allows clinicians to characterize all types of valve lesion. In addition, evolving techniques in interventional cardiology and cardiac surgery, guided by quantitative outcome analysis, have reduced the morbidity and mortality of these procedures.Reflecting all the above and evidence-based medical practice, the authors aim to provide a concise and straightforward guide to the recognition and management of valvular heart disease, complemented by current guidelines and abundant high quality images. It will be a valuable reference for all involved in the care of patients with valvular heart disease, including cardiologists in practice and training, young hospital doctors, general physicians, cardiac nurse specialists, and medical students.Table of ContentsApproach to the Patient. Cardiac Murmurs. Prevention of Valvular Heart Disease. Aortic Stenosis. Chronic Aortic Regurgitation. Acute Aortic Regurgitation. Mitral Stenosis. Mitral Valve Prolapse. Chronic Mitral Regurgitation. Acute Mitral Regurgitation. Pulmonic Stenosis. Pulmonic Regurgitation. Tricuspid Stenosis. Tricuspid Regurgitation. Mixed Single Valve Disease. Multiple Valve Disease. Infective Endocarditis. Drug Induced Valvular Heart Disease. Prosthetic Heart Valves. Pregnancy and Valvular Heart Disease. Valvular Heart Disease in the Elderly. Quality Improvement in Valvular Heart Disease.

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Book SynopsisThis highly illustrated, well-written and beautifully produced text is aimed at cardiologists and internal medical doctors, whether qualified or in-training, who are not specialized in the field of congenital heart disease, who will, nevertheless, meet these patients more and more often in their daily practice. The complicated subject of congenital heart disease is written in a very simple, easy and comprehensive way. Congenital Heart Disease in Adults provides a brief overview of the morphology, physiology, diagnostic methods, therapy and prognosis of the most common congenital heart disease in adulthood.Written by international leaders in the field of adult congenital heart disease, this superb guide provides practical, beneficial consultation for every situationTable of ContentsForeword – Joseph K Perloff, Preface, 1 History, 2 Prevalence of congenital heart disease in adulthood, 3 Atrial septal defect, 4 Patent foramen ovale, 5 Atrioventricular septal defect, 6 Ventricular septal defect, 7 Tetralogy of Fallot, 8 Coarctation of the aorta, 9 Bicuspid aortic valve and diseases of the aorta, 10 Pulmonary stenosis, 11 Transposition of the great arteries, 12 Congenitally corrected transposition of the great arteries, 13 Patent ductus arteriosus, 14 Ebstein’s anomaly of the tricuspid valve, 15 Functionally single ventricle, Fontan procedure – univentricular heart/circulation, 16 Cyanotic congenital heart diseases in adulthood, 17 Pulmonary atresia with ventricular septal defect, 18 Congenital coronary artery anomalies, 19 Persistent left superior vena cava, 20 Anomalous pulmonary venous connection, 21 Psychosocial issues, 22 Cardiac injury during surgery in childhood, 23 Terminology remarks, Index

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Book SynopsisTextbook of Peripheral Vascular Intervention, Second Edition, discusses therapies that can make a real difference in the lives of patients. As there are increasing demands for effective, less invasive approaches to therapies for critical limb ischemia, chronic total occlusions, as well as therapies for some subsets.Table of ContentsSECTION I: INTRODUCTION Epidemiology and pathophysiology of peripheral arterial disease (PAD); GI Pandele and C Dima-Cozma The endovascular suite and equipment; K Dougherty and Z Krajcer SECTION II: TECHNIQUES Arterial access for endovascular interventions: vascular access; JS Jenkins Arterial access for endovascular interventions: radial and brachial arterial access; PW McMullan Jr and JS Jenkins Arterial access for endovascular interventions: transradial approach; I Henry, M Henry, and M Hugel Arterial access for endovascular interventions: popliteal access to peripheral procedures; M Henry, I Henry, and M Hugel Introducer sheaths, catheters, guiding catheters, and guidewires; K Dougherty and Z Krajcer Percutaneous transluminal angioplasty; T Collins and PW McMullan Jr Cutting balloon angioplasty; S Tyagi SilverHawk(R) atherectomy device; RS Gammon and JR Nelson Percutaneous peripheral atherectomy using the Rotablator; I Henry, M Henry, and M Hugel A new rotational thrombectomy and atherectomy catheter: the Rotarex system; I Henry, M Henry, and M Hugel Orbital atherectomy system: a novel means of peripheral vascular rotational atherectomy; DT Cragen and RR Heuser Subintimal angioplasty; G Markose and A Bolia Recanalization devices for chronic total occlusions (including optical coherent reflectometry); G Baweja and RR Heuser Catheter-directed intra-arterial thrombolytic therapy; NN Khanna and RR Kasliwal Thromboaspiration and thrombectomy in peripheral vessels; NN Khanna The future of thrombolysis; T McNamara Endovascular treatment for acute and chronic lower extremity deep vein thrombosis; PE Thorpe and FJ Osse Stents; RR Heuser, KL Waters, CW Hatler, and LM Kelly Role of covered stents in peripheral arterial diseases; M Henry, I Henry, and M Hugel Embolic protection devices; M Henry, I Henry, A Polydorou, and M Hugel Vascular closure devices; ZG Turi Other techniques of percutaneous intervention: retrieval devices, embolization therapy, and angiogenesis; JA Silva and JS Jenkins SECTION III: NEUROVASCULAR; Epidemiology and pathophysiology of neurovascular disease; C Klonaris, A Papapetrou, and A Katsargyris Neuroradiological anatomy; MH Wholey and WS Wu Doppler ultrasound and carotid angioplasty: carotid ultrasonography and transcranial Doppler; S Kownator and F Luizy The value of transcranial Doppler ultrasonography before, during, and after surgery for carotid occlusive disease; NM Bornstein and AY Gur Carotid plaque characterization using ultrasound; AN Nicolaides, M Griffin, S Kakkos, G Geroulakos, E Kyriacou, and N Georgiou Cerebral perfusion imaging; W-J Jiang Stent-assisted angioplasty for symptomatic atherosclerotic intracranial stenosis; W-J Jiang Intracranial stenting for cerebrovascular pathology; EI Levy, AS Boulos, BR Bendok, SH Kim, AI Qureshi, LR Guterman, and LN Hopkins The stroke unit; P Lylyk and JF Vila Interventional treatment of acute ischemic stroke: past, present, and future; CS Eddleman, ZA Hage, DL Surdell, EI Levy, RM Samuelson, YA Mikhaeil, and BR Bendok Carotid angioplasty and stenting under protection: techniques, indications, results, and limitations; M Henry, A Polydorou, I Henry, Ad Polydorou, and M Hugel Complications of internal carotid artery stenting and their management; DL Surdell, ZA Hage, CS Eddleman, S Das, E Duckworth, MK Eskandari, IA Awad, HH Batjer, and BR Bendok Which patients should be referred for surgical endarterectomy and not have carotid stenting; FJ Criado and C Gallagher Common carotid artery: PTA stenting; J Franke, G Robertson, and H Sievert Percutaneous transluminal angioplasty of the subclavian arteries; M Henry, I Henry, A Polydorou, Ad Polydorou, and M Hugel Percutaneous transluminal angioplasty and stenting of extracranial vertebral artery stenosis; V Polydorou, I Henry, A Polydorou, M Henry, Ad Polydorou, J Stephanides, M Hugel, and S Anagnostopoulou Elective endovascular revascularization of the intracranial cerebral arteries; HC Schumacher, PM Meyers, B Bateman, and RT Higashida SECTION IV: UPPER EXTREMITY ARTERIAL DISEASES Upper extremity arterial diseases; J Laredo and BB Lee Compression syndromes of the superior thoracic aperture; JE Molina SECTION V: THORACIC AORTA Thoracic aorta: epidemiology and pathophysiology; EB Diethrich Radiology and anatomy of the thoracic aorta; AR Owen, GH Roditi, and AW Reid Thoracic aorta: thoracic aortic aneurysms; EB Diethrich Thoracic aortic dissection; J May, GH White, and JP Harris SECTION VI: ABDOMINAL AORTA Abdominal aortic aneurysm treatment by endoluminal exclusion: a historical perspective; JC Parodi, CJ Schonholz, and RR Heuser Role of Doppler ultrasound in the assessment of peripheral vascular disease; K Irshad, M Ali, AW Reid, A Sinha, and DB Reid Abdominal aortic dissections; OC Morcos, JC Pereda, and ML Marin Endovascular treatment of abdominal aortic occlusive disease; C Klonaris and A Katsargyris SECTION VII: THORACOABDOMINAL ANEURYSMS AND DISSECTIONS Thoracoabdominal aneurysms and dissections: current indications and management; JF Dowdall, Q Lu, and RK Greenberg SECTION VIII: ATHEROSCLEROTIC RENAL ARTERY STENOSIS Atherosclerotic renal artery stenosis: epidemiology and pathophysiology; KI Paraskevas, DP Mikhailidis, and G Hamilton Radiological assessment of the renal arteries; A Al-Kutoubi Endovascular treatment of a renal artery stenosis: techniques, indications, and result; M Henry, I Henry, A Polydorou, Ad Polydorou, and M Hugel Renal angioplasty and stenting under protection devices; M Henry, I Henry, A Polydorou, Ad Polydorou, and M Hugel Renal artery stenosis: when to refer to surgery?; C Klonaris, A Katsargyris, and A Giannopoulos Non-atherosclerotic renovascular disease; JM Garasic and K Rosenfield SECTION IX: CELIAC AND MESENTERIC ARTERIES Etiology, natural history, and pathophysiology of mesenteric ischemia; JA Silva Assessment of mesenteric ischemia; JA Silva Conventional angiography, CTA, and MRA of the mesenteric arteries; Y-W Chi and JA Silva Duplex ultrasound of the mesenteric arteries; Y-W Chi and JA Silva Endovascular therapy for mesenteric ischemia; JA Silva Mesenteric ischemia: surgical revascularization and indications for surgery; JA Silva and DE Allie SECTION X: LOWER EXTREMITY Epidemiology and pathophysiology of peripheral arterial disease of the lower extremities; C Klonaris, A Papapetrou, and A Giannopoulos Lower extremity arterial disease assessment; KF Murphy, K Irshad, A Sinha, and DB Reid Lower extremity: other techniques; ML Brennan and L Cho Iliac occlusive diseases; DT Cragen and RR Heuser Procedures for the hypogastric artery; J Cynamon and P Prabhaker Femoropopliteal disease; E Calabrese and F Camerano When to refer to surgery for femoropopliteal disease; N Morrissey Infrapopliteal arterial diseases: angioplasty and stenting; E Calabrese Critical limb ischemia; DE Allie, CJ Hebert, EV Mitran, CM Walker, and RR Patlola Acute limb ischemia; DE Allie, CJ Hebert, EV Mitran, CM Walker, and RR Patlola Endovascular treatment for infrainguinal failing graft; A de Carvalho Lobato and DF Colli Jr Thromboangiitis obliterans (Buerger's disease); A Pokrovsky and AV Chupin Percutaneous endovascular treatment of peripheral aneurysms; M Henry, I Henry, and M Hugel SECTION XI: OTHER LOCALIZATIONS Embolization in peripheral territory; CJ Schonholz, E Mendaro, and K Ehrens Uterine artery embolization for fibroids; J Pisco and M Duarte Hemodialysis access intervention; E Calabrese and B Yasin Endovascular surgery in treatment of some congenital heart defects; BG Alekyan, VP Podzolkov, VA Garibyan, MG Pursanov, KE Kardenas, and E Yu Danilov Endovascular treatment of some congenital diseases: hemangiomas and vascular malformations; BB Lee, J Laredo, DH Deaton, and RF Neville SECTION XII: UNUSUAL VASCULAR DISEASES OF THE EXTREMITIES Endovascular management of Budd-Chiari syndrome - suprahepatic inferior vena cava occlusive disease; BB Lee, J Laredo, DH Deaton, and RF Neville Unusual vascular conditions of the extremities; DH Deaton, RF Neville, J Laredo, and BB Lee Interventions in inflammatory arterial disease; S Rajagopal and L Gopalakrishnan Vascular involvement in Behcet's disease; TW Kwon SECTION XIII: MULTIVASCULAR DISEASE Potential of endovascular surgery in the treatment of patients with ischemic heart disease associated with other arterial pools' pathology; LB Bockeria, BG Alekyan, Yu I Buziashvili, EZ Golukhova, TG Niritina, NP Mironov, AV Ter-Akopyan, NV Zakarian, and AV Staferov SECTION XIV: TREATMENTS FOR RESTENOSIS Pathophysiology of restenosis; E Kedhi, J-F Tanguay, and L Bilodeau Interventional therapy: new approaches; E Kedhi and L Bilodeau Update on peripheral vascular brachytherapy; R Waksman Gene-based and angiogenesis therapy in cardiovascular diseases; R Baffour, S Fuchs, and R Kornowski SECTION XV: PTA/STENTING COMPLICATIONS Complications of peripheral interventions; DT Cragen and RR Heuser Contrast-induced nephropathy; G Marenzi and AL Bartorelli SECTION XVI: PHARMACOLOGICAL TREATMENTS AND RISK FACTOR MANAGEMENT Pharmacological treatment in peripheral arterial disease; GI Pandele and C Dima-Cozma Risk factors in peripheral arterial disease; GI Pandele and C Dima-Cozma SECTION XVII: VENOUS DISEASE The anatomy, epidemiology, and pathophysiology of venous disease; JI Greenberg, N Angle, and J Bergan Diagnostic evaluation of venous disease; B Abai and N Labropoulos Contrast imaging studies of the lower extremity; GE Pineda and D Mukherjee Interventional therapy for pulmonary embolism; S Faintuch, FB Collares, and GM Martinez Salazar Superior and inferior vena cava thrombosis; J Pisco and M Duarte Varicose veins; CK Shortell and J Bergan Endovenous laser therapy for varicose veins; NN Khanna Vena caval filters; NN Khanna Foam treatment of varicose veins; JI Greenberg, N Angle, and J Bergan INDEX

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Book SynopsisModern signal and image acquisition systems used in the field of cardiology acquire, analyze, and store data digitally. Surface electrocardiography, intra-cardiac electrogram recording, echocardiograms, x-ray, magnetic resonance imaging, and computed tomography are among the modalities in the cardiology field where signal processing is applied. Digital signal processing techniques allow us to automate many of the analyses that had previously been done manually with greater precision, accuracy and speed, as well as detect features and patterns in data that may be too subtle to observe by eye. As more cardiologists are becoming more reliant on such technology, a basic understanding of digital signals and the techniques used to extract information from these signals are required. Trade ReviewFrom the reviews:“This is a review of the technical aspects of signal processing and its application to various areas of cardiology. … It is intended for cardiologists, physicians in training, and students interested in the basics of signal processing. … This well-organized book provides readers with a clearer understanding of signal processing and data acquisition related to cardiovascular imaging.” (Amit Prasad, Doody’s Review Service, March, 2011)Table of ContentsFundamental Signal and Image Processing Concepts.- Architecture of the Basic Physiologic Recorder.- Analog and Digital Signals.- Signals in the Frequency Domain.- Filters.- Techniques for Event and Feature Detection.- Alternative Techniques for Rate Estimation.- Signal Averaging for Noise Reduction.- Data Compression.- Image Processing.- Cardiology Applications.- Electrocardiography.- Intravascular and Intracardiac Pressure Measurement.- Blood Pressure and Pulse Oximetry.- Coronary Angiography.- Echocardiography.- Nuclear Cardiology: SPECT and PET.- Magnetic Resonance Imaging.- Computed Tomography.- ECG Telemetry and Long Term Electrocardiography.- Intracardiac Electrograms.- Advanced Signal Processing Applications of the ECG: T-Wave Alternans, Heart Rate Variability, and the Signal Averaged ECG.- Digital Stethoscopes.

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Book SynopsisVitamin C (ascorbic acid) is a key vitamin to animals and plants. This book looks at all aspects of vitamin C; its chemical and biochemical properties, its role in various plants and animals and its effect on our health. Written by an international team of experts, together they represent much of the expertise on vitamin C throughout the world.Table of Contents1. Ascorbate Biosynthesis in Plants, Fungi and Animals. 2. Ascorbic Acid Catabolism- Breakdown Pathways and Products in Plants and Animals. 3. Application of Biotechnology to Ascorbic Acid Manufacture. 4. Ascorbic Acid and Oxidative Stress/ Photoprotection in Plants. 5. Ascorbic Acid and Plant Growth. 6. Ascorbic Acid Uptake and Transport. 7. Membrane Redox Proteins involved in Ascorbate-Mediated Reactions. 8. Ascorbic Acid Recycling. 9. How does Ascorbic Acid Prevent Scurvy? 10. Function of Ascorbic Acid as an Antioxidant. 11. Ascorbic Acid and DNA Damage/ Antioxidant Pro-oxidant Effects of Ascorbate. 12. Ascorbic Acid and Aging. 13. Ascorbic Acid in the Central Nervous System.14. Ascorbic Acid and Inflammation. 15. Ascorbic Acid as an Antioxidant in Atherosclerosis. 16. What Intake of Vitamin C is Required for Optimal Human Health?

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Book SynopsisThis is the first textbook entirely dedicated to the endovascular treatment of complications related to arteriovenous accesses for hemodialysis (native fistulas and prosthetic grafts). The book addresses the anatomy of upper limb arteries and veins as well as the clinical presentation of patients and the way to perform and read a fistulogram. Many details and illustrations are provided, clarifying the subtleties in catheterization and the dilation of stenoses. From a strategic point of view, it is explained for the first time that many stenoses must either be ignored or deliberately underdilated. A wealth of images helps to understand the different stages of access recovery from thrombosis. As the number of incident dialysis patients is increasing by 5% every year, this is a field of growing interest. In testament to this there are several annual or bi-annual meetings held by numerous national and international societies (vascularaccesssociety.com, sfav.org, vasamd.org, dialysiscontroversies.org, asdin.org).Table of ContentsGlory and weakness of interventional radiology in dialysis accesses.- The nephrologist, the interventional radiologist and the place of the vascular access in the treatment of end stage renal disease.- Vascular access strategy.- Natural history of vascular accesses.- Radiological anatomy and pre-operative imaging of upper limb vessels.- Which indications and which imaging method for the dialysis access?.- Psychological and clinical aspects.- Clinical pre-requisites prior to angiography.- Angiography (« fistulography »).- Dilation and stents.- Hand ischemia.- How dealing with the thrombosed access?.- Percutaneous occlusion of dialysis accesses.- Diagnostic and interventional radiology of arterio-venous accesses for hemodialysis: a European perspective.- Clinical complications during and after endovascular treatments.- Immediate and long-term results of interventional radiology in dialysis accesses.- Annexes. Addenda.

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Book SynopsisThis book provides comprehensive information on transcatheter aortic valve implantation (TAVI), which was introduced for the treatment of aortic valve disease less than two decades ago. It explains how TAVI has delivered satisfactory results even in high and intermediate risk patients and outlines how it continues to evolve, thus requiring awareness of state of the art approaches to indication, risk stratification, device choice, procedure, and follow-up. In addition, it reports on the complex and multidisciplinary approach needed to maximize the efficacy, safety, and appropriateness of TAVI, providing detailed clinical, interventional and surgical perspectives focusing on the development of this cardiovascular intervention. Starting with the history of TAVI, addressing the interventional anatomy of aortic valve disease, and reporting on the expert authors’ day-to-day experiences, this highly informative book offers an essential update for all cardiologists and surgeons interested in transcatheter aortic valve implantation, as well as any clinician, decision-maker and stakeholder involved in patient selection, procedural management, and follow-up.Trade Review“This intended audience is cardiologists or cardiac surgeons interested in TAVI as well as members of the heart team involved in patient selection, procedural management, and follow‐up. … This will be an excellent resource for beginning fellows or most advanced clinicians who would like to stay abreast of this ever‐changing field.” (Adam C Harless, Doody's Book Reviews, October 11, 2019)Table of ContentsI – Pathophysiological and translational perspectives.- 1 History of transcatheter aortic valve implantation.- 2 Interventional anatomy of aortic valve disease.- 3 Pathophysiology of aortic.- 4 Pathophysiology of aortic regurigation.- 5 Pathophysiology of degenerated bioprosthesis.- 6 Role of inflammation in native and prosthetic aortic valve disease.- 7 Predictive computational models of transcatheter aortic valve implantation.- 8 Hemodynamic issues with transcatheter aortic valve implantation.- 9 Risk scores for aortic valve.- II Clinical perspectives.- 10 Role of rest and stress echocardiography in transcatheter aortic valve implantation.- 11 Role of computed tomography in transcatheter aortic valve implantation.- 12 Role of magnetic resonance imaging in transcatheter aortic valve implantation.- 13 Concomitant coronary artery disease and aortic stenosis.- 14 Comparison of transcatheter aortic valve implantation to medical therapy in prohibitive risk patients.- 15 Clinical and imaging follow-up after transcatheter aortic valve implantation.- 16 Biomarkers before, during and after transcatheter aortic valve implantation.- 17 Prognostic impact of aortic regurgitation and paravalvular leak.- 18 Leaflet motion abnormalities.- 19 Gender-related differences in transcatheter aortic valve implantation.- 20 Implementation issues for transcatheter aortic valve implantation: cost-effectiveness, wait-times and volume-outcome balance.- III Interventional perspectives.- 21 Transfemoral access management for transcatheter aortic valve implantation.- 22 Challenging anathomy for transcatheter aortic valve implantation.- 23 Abbott Vascular program for transcatheter aortic valve implantation.- 24 Boston Scientific program for transcatheter aortic valve implantation.- 25 Edwards program for transcatheter aortic valve implantation.- 26 JenaValve program for transcatheter aortic valve implantation.- 27 Medtronic program for transcatheter aortic valve implantation.- 28 Self-expanding vs balloon-expandable devices for transcatheter aortic valve implantation.- 29 Individualized device choice for transcatheter aortic valve implantation.- 30 Predilation for transcatheter aortic valve implantation.- 31 Postdilation for transcatheter aortic valve implantation.- 32 Embolic protection devices for transcatheter aortic valve implantation.- 33 Antithrombotic therapy during and after transcatheter aortic valve implantation.- 34 Contrast induced nephropathy and transcatheter aortic valve implantation.- 35 Conduction disorders and permanent pacemaker requirement after transcatheter aortic valve implantation.- 36 Systolic dysfunction and hemodynamic support in patients candidate for transcatheter aortic valve implantation.- 37 Radiation exposure in transcatheter aortic valve implantation.- 38 Procedure efficiency in transcatheter aortic valve implantation.- 39 Predictors of success for transcatheter aortic valve implantation.- 40 Learning curve, procedural volumes and relationship with clinical outcomes for transcatheter aortic valve implantation.- 41 Aortic valvuloplasty as bridge vs destination therapy.- IV Surgical perspectives.- 42 Role of the heart team in decision making for transcatheter aortic valve implantation.- 43 Alternative accesses for transcatheter aortic valve implantation.- 44 Comparison of transcatheter aortic valve implantation to surgery in intermediate risk patients.- 45 New approaches for aortic valve disease: from transcatheter aortic valve implantation to sutureless aortic valves.- 46 Hybrid procedures for aortic valve disease: transapical aortic valve implantation through lower left anterior mini-thoracotomy vs Edwards Intuity valve implantation through upper right anterior mini-thoracotomy.- V Future perspectives.- 47 Medical treatment for aortic valve disease.- 48 Transcatheter aortic valve implantation for pure aortic regurgitation.- 49 New-generation devices for transcatheter aortic valve implantation.- 50 Bioresorbable valve for transcatheter aortic valve implantation: tomorrow's world from preclinical to clinical.- 51 Focus on transcatheter aortic valve implantation in low risk patients.- 52 Conclusion.

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Book SynopsisA highly successful introduction to echocardiography, now in a new and enhanced edition In diagnostic cardiology, the effectiveness and reliability of state-of-the-art echocardiography is unsurpassed but-as with all ultrasound examinations-the results are highly operator dependent. The second edition of Boehmeke's Pocket Atlas of Echocardiography is concise and portable, including all the information necessary to perform and read echocardiograms, and to navigate the bewildering number of imaging planes that transect the heart, with ease and confidence. Key features: More than 400 illustrations, including sharp, clear echocardiograms, corresponding full-color schematic diagrams, and 3-D images. For this new edition, all images showing cardiac disease have been post-processed to make them clearer and in more accurate relation to the explanatory drawings Detailed descriptions of all the acoustic windows and imaging planes for every echocardiogram A practical overview of the typical patient examination, including imaging and patient positioning All cardiac diseases are shown: valvular heart disease, coronary heart disease, cardiomyopathies, prosthetic valves, carditis, septal defects, hypertensive heart diseases, intracardiac masses; depicted in B-mode, M-mode, Doppler and color Doppler New to the second edition: nearly 80 videos are now accessible on the Thieme MediaCenter showing normal views and many pathologies in video mode Table of ContentsExamination 1 Imaging and Patient Position 2 Parasternal Long-Axis View 3 Parasternal Short-Axis View 4 Apical Windows 5 Suprasternal Window 6 Subcostal Window M-Mode and Doppler Echocardiography 7 M-Mode Echocardiography 8 Doppler Echocardiography Cardiac Abnormalities 9 Valvular Heart Disease 10 Coronary Heart Disease 11 Cardiomyopathies 12 Prosthetic Valves 13 Carditis 14 Septal Defects 15 Hypertensive Heart Diseases 16 Intracardiac Masses

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Book SynopsisThis book is a detailed guide to a new integrative approach to the prevention and treatment of various cardiac disorders and risk factors, including coronary artery disease, congestive heart failure, arrhythmias, dyslipidemia, and hypertension. This approach combines various strategies, including metabolic cardiology, low-dose medicine, exercise programs, stress management programs, evaluation for inherited risk factors, and various other healing modalities. Metabolic cardiology focuses on the prevention, management, and treatment of cardiovascular disease at the cellular level through biochemical interventions with nutritional supplements that can promote energy production in the heart. Low-dose medicine, on the other hand, interprets pathological phenomena as an imbalance in intercellular signaling that may be corrected through the administration of low physiological doses of messenger molecules. Therapies outside of mainstream medicine may also be deployed in integrative cardiology, for example acupuncture, herbal medicine, and homeopathy. Integrative Cardiology will be of interest to all practitioners wishing to learn about an approach that incorporates the incredible advances in medication and technology with a focus on nutrition, lifestyle, and mind–body influences.Trade Review“The book is designed to provide additional tools for physicians to use in their therapeutic intervention strategies in often complex pathological situations in cardiovascular disease. … The book is well written, easy to read, and uses numerous color graphs, figures, and tables to supplement the text. This tool for practicing clinicians provides a complete source of information about the use of complementary therapies in treating the whole patient with cardiovascular disease.” (Joseph A. Randy Englert III, Doody’s Book Reviews, June, 2017) Table of ContentsPart I The basis of integration: Herbal Medicine.- Homeopathy and cardiovascular disease.- Low Dose therapy for the treatment of Low Grade Inflammation.- Acupunture and cardiology.- Metabolic Cardiology.- Medicinal Mushrooms.- Microbiome and cardiac health.- Endocrine system and cardiovascular disease.- Cardiovascular Aging.- Nutrition and cardiac health.- PsicoNeuroEndocrinImmunology prospective.- Meditation and stress management in cardiology.- Ozone Therapy in cardiovascular disease.- Part II Integrated approach to Cardiovascular Disease: Integrated approach to dyslipidemia.- Integrated approach to Hypertension.- Integrated approach to Coronary Artery Disease.- Integrated approach to Heart Failure.- Integrated approach to Arrhythmias.- Integrated approach to oncologic supportive medicine.- Heart and Skin (the paradigm of cytokines-mediated cardiovascular metabolic disease in psoriasis).

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Book SynopsisThis book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control. Table of ContentsPart I: General Aspects.- 1. Introduction: Definition and Classification of Arterial Pressure Phenotypes.- 2. Diagnostic and Prognostic Significance of Blood Pressure Indices.- 3. Role of Circadian Rhythms and Seasonal Variation in BP Levels.- 4. Natural History of Treated and Untreated Hypertension.- Part II: Mechanisms of Hypertension Development.- 5. The Kidneys, Volume and Blood Pressure Regulation, and Hypertension.- 6. Nervous System.- 7. Hormonal Systems.- 8. Vasoactive Peptides.- 9. Endothelial Function.- 10. Genetics of Blood Pressure and Hypertension.- Part III: Hypertension Phenotypes: Monogenic Syndromes.- 11. Monogenic Forms of Hypertension.- 12. Arterial Hypertension in Turner Syndrome.- Part IV: Hypertension Phenotypes: The Heart.- 13. Hypertensive Heart Disease.- 14. Perioperative Cardiac Surgery Hypertension.- 15. Hypertension: Supravalvular Aortic Stenosis.- 16. Coarctation of the Aorta.- 17. Atrial Fibrillation and Hypertension: Two Entities That Usually Coexist.- Part V: Hypertension Phenotypes: The Central Nervous System and the Brain.- 18. Sleep Disturbances/Sleep Apnea.- 19. Stress and Hypertension.- 20. Central Nervous System Disorders: Transient Ischemic Attack and Stroke (Ischemic/Hemorrhagic).- Part VI: Hypertension Phenotypes: The Kidney.- 21. Chronic Kidney Disease.- 22. Calculus Renal Disease.- 23. Uric Acid-Hypertension Relationships.- 24. Hypertension in Dialysis Patients: Clinical Edidemiology, Pathogenesis, Diagnosis, and Treatment.- 25. Renovascular Hypertension.- 26. Molecular Pathways in Hypertensive Renal Damage.- 27. Determinants of Hypertensive Renal Disease and Its Progression.- Part VII: Hypertension Phenotypes: Endocrine Causes.- 28. Cushing's Syndrome and Glucocorticoid Excess.- 29. Primary Aldosteronism and Its Various Scenarios.- 30. Severe Paroxysmal Hypertension (Pseudopheochromocytoma).- 31. Paroxysmal Hypertension: Pheochromocytoma.- 32. Hypertension in Thyroid Disorders.- 33. Primary Hyperparathyroidism.- Part VIII: Special Types of Hypertension.- 34. Phenotypic Changes in the Transition from Prehypertension to Established Hypertension.- 35. White Coat and Masked Hypertension.- 36. Isolated Systolic Hypertension: In the Young and in the Elderly.- 37. Treatment of Resistant Hypertension.- 38. Accelerated / Malignant Hypertension.- 39. Nocturnal Hypertension.- 40. Salt and Hypertension.- 41. Diabetes Mellitus and Hypertension.- 42. Obesity and Metabolic Syndrome Hypertension.- 43. Secondary Hypertension: Infrequently Considered Aspects—Illicit/Recreational Substances, Herbal Remedies, and Drug-Associated Hypertension.- Part IX: Hypertensive Phenotypes: Blood Pressure Disorders of Pregnancy and Pediatric Hypertension.- 44. Hypertensive Disorders of Pregnancy.- 45. Blood Pressure Trends in Children and Adolescents: Predictors of Blood Pressure Elevation in Children and Adolescents.- 46. Hypertension in Children and Adolescents.- Part X: Management and Therapeutic Approaches.- 47. What Is New and What Is Different in Recent Guidelines on Antihypertensive Treatment? Looking Forward to Guidelines Reappraisal.- 48. Place of Invasive Procedures in Blood Pressure Control.- 49. Is Hypertension-Related Target Organ Involvement/Damage Reversible/Preventable?

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Book SynopsisThis book spans topics in both congenital and acquired right heart disease providing readers with detailed information on the physiology, anatomy and myocardial mechanics of the right ventricle (RV), while describing the use of echo and MRI imaging to diagnose, and new developments in surgery and cardiac catheterization to treat. Right Ventricular Physiology, Adaptation and Failure in Congenital and Acquired Heart Disease includes extensive discussion of RV-pulmonary interactions, pulmonary hypertension and ventricular-ventricular interactions, including specific topics in embryology, fetal RV function, RV mechanics, pathophysiology of RV adaptation/ failure, molecular aspects of RV dysfunction, congenital heart disease, pulmonary arterial hypertension, pulmonary valve replacement, stem cell and future therapies.​ It is thus important reading for all cardiovascular medicine professionals, but especially pediatric cardiologists and surgeons, those who manage these patients in the cardiac care unit and investigators studying the RV. Table of ContentsIntroduction.- Embryological origins: How does the RV form?.- The fetal RV: systemic powerhouse or prone to fail?.- Metabolism and bioenergetics in the hypertrophied RV: what is different from the LV?.- Why does the RV myocardium fail?.- Does the RV really contract differently from the LV?.- How does the pressure loaded RV adapt and why does it fail? Macro and molecular perspectives.- Novel mechanisms of lung injury and repair in PAH: does success in the lab translate to hope for our patients?.- Right-left ventricular interactions in PAH.- From M-mode to 3D echo:-what should we use to assess RV function?.- What does MRI offer beyond volumes?.- Why is the RV different in TOF and in ASD?.- RV dyssynchrony and cardiac resynchronization therapy: New insights into mechanisms and pathophysiology.- The single right ventricle in the Fontan circulation: How does it work and why does it fail?.- Transcatheter pulmonary valve replacement: When should we pull the trigger? What do we hope to achieve?.- What should the echocardiographer tell me to plan tricuspid valve repair?.- Investigating the RV: What is the path going forward?.- Ventricular-vascular coupling in PAH: An engineer’s perspective is relevant to the clinician.- The RV in cardiac transplantation-How do we know if it’s going to cope and what do we do when it doesn’t?.- Does the RV really contract differently from the LV?.- How can computer models contribute to the clinician’s assessment of ventricular-ventricular interactions, ventricular-vascular interactions and RV failure?.- Can the RV support the failing LV.- Ebstein anomaly: Does echocardiographic assessment determine surgical repair?.- Arrhythmogenic right ventricular cardiomyopathy: Why does it happen and how do we make the diagnosis?.- Can surgeons preserve RV function in hypoplastic left heart syndrome?.- The RV in ccTGA: Why does it fail? Can we prevent it?.- Drugs?.- Assist devices.- News on the horizon.

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book SynopsisDie rasche Entwicklung, vor allem invasiver aber auch nichtinvasiver Ver­ fahren, bei der Therapie der peripheren arteriellen Verschlußkrankheit in den letzten Jahren macht eine aktuelle Standortbestimmung not­ wendig. Dies um so mehr, als die periphere arterielle Verschlußkrankheit in therapeutischer Hinsicht von verschiedenen Disziplinen (interni­ stische Angiologie, Gefäßchirurgie und interventionelle Radiologie) be­ treut wird. Es war daher sinnvoll, eine derartige Standortbestimmung unter Beteiligung erfahrener Experten aus den drei genannten Teilgebieten durchzuführen. Ziel eines dazu veranstalteten Symposiums im Herbst 1990 in Malta war es, aktuelle Therapieprinzipien im einzelnen darzustellen, ihre Bedeutung kri­ tisch zu werten und interdisziplinär zu diskutieren. Von einer starren Syste­ matik bei der Erstellung des Programms wurde dabei bewußt Abstand genommen, um den teilnehmenden Autoren möglichst große Freiheit bei der Auswahl ihres Themas zu lassen. Trotzdem, oder vielleicht gerade deswegen, kam es bei der Zusammenstellung des Programms zu einer umfassenden Darstellung der heute wichtigsten therapeutischen Prinzipien bei der peri­ pheren arteriellen Verschlußkrankheit. Dies wurde sowohl bei dem Sympo­ sium im Herbst 1990 deutlich als auch bei der Zusammenstellung dieses Buches. Der vorliegende Band enthält nicht nur die Manuskripte der einzelnen in Malta gehaltenen Vorträge, sondern auch Teile der zu diesen Vorträgen geführten Diskussionen, so daß der Leser auch über einige Fragen oder Kri­ tikpunkte informiert wird. Aus diesem Grund stellt das vorliegende Buch meines Erachtens eine gute 5 Vorwort Grundlage für die Beschäftigung mit der aktuellen Therapie der peripheren arteriellen Verschlußkrankheit dar.Table of ContentsDer femoro-popliteale Bypass: Venen- oder Kunststofftransplantate?.- Der femoro-crurale Bypass, Problematik und Lösungsansätze.- Adjuvante Therapie bei femoro-distaler Bypasschirurgie.- Konservative Therapie der arteriellen Verschlußkrankheit aus chirurgischer Sicht.- Perkutane transluminale Angioplastie.- Antithrombotische Therapie nach Rekanalisation und Bypassoperation bei peripherer arterieller Verschlußkrankheit.- Lokale Lyse, Atherektomie, Stent.- Chancen und Grenzen der Bewegungstherapie bei peripherer arterieller Verschlußkrankheit.- Medikamentöse Vasodilatation bei peripherer arterieller Verschlußkrankheit — Eine alte Kontroverse.- Klinische Wirksamkeit vasoaktiver Medikamente im Stadium II der peripheren arteriellen Verschlußkrankheit.- Kontrolle therapeutisch relevanter Parameter bei der Behandlung der peripheren arteriellen VerschluBkrankheit.

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Book SynopsisCT signs of early cerebral infarction are subtle within the first 6 hours after symptom onset, but important to recognize. The CT reading panel of ECASS wants to share its experience by publishing this series of early CT scans from study patients in order to improve early recognition of ischemic infarction by CT and thus to improve patient care, and to provide material for practice. In this book each CT scan can be read with and without neuroradiological description. Follow-up scans of each case confirm early findings.Table of ContentsHow to Use this Book.- Patient Scans: Patients 1–20.- Detectability, Prevalence, and Significance of Early CT Signs of Hemispheric Infarction.- Hypodensity of Brain Parenchyma.- Focal Brain Swelling.- Hyperdense Middle Cerebral Artery Sign (HMCAS).- Pathophysiology of Early Parenchymal Hypodensity and Ischemic Brain Swelling and Consequences for Therapy.- Performing CT in Acute Ischemic Stroke: Practical Considerations.- How to Estimate the Extent of Early Ischemic Brain Damage.- Conclusions.- References.

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Book SynopsisNach einem Herzeingriff - einer Operation oder dem Aufdehnen der Herzkranzgefäße - stellen sich viele Fragen:- Was liegt meiner Herzerkrankung zugrunde?- Wie kann ich behandelt werden? Welche Komplikationen kann es geben?- Wie verhalte ich mich in der ersten Zeit nach der Operation?- Wie gestalte ich meinen Alltag nach der Operation? Was darf ich, wo muss ich vorsichtig sein?- Wie lebe ich, um meine Gesundheit zu erhalten?Zuverlässige und detaillierte Antworten geben Ihnen drei erfahrene Herzchirurgen des Herzzentrums Lahr in diesem Buch.Table of ContentsBiologie des Herzens.- Die koronare Herzerkrankung und ihre Behandlung.- Herzklappenerkrankungen und Herzklappenoperationen.- Aortenerkrankungen und Aortenoperationen.- Welche Komplikationen gibt es nach dem Herzeingriff?- Empfehlungen für die Patientinnen und Patienten zum Verhalten nach einem Herzeingriff.- Wichtige Fragen nach dem Herzeingriff.- Gesundes Leben nach dem Herzeingriff.- Herzschrittmacher und Defibrillatoren.- Glossar.

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Book SynopsisUmfassendes Lehr- und Nachschlagewerk zur schnellen Orientierung in der modernen Diagnostik und Therapie.Table of Contents1 Einführung.- 2 Untersuchungsmethoden.- 3 Pathophysiologische Grundlagen.- 4 Anomalien des linken Ventrikels und der Aorta.- 5 Anomalien des rechten Ventrikels und der Arteria pulmonalis.- 6 Angeborene Anomalien der Lungengefäße.- 7 Angeborene Herzfehler mit überwiegendem Links-rechts-Shunt.- 8 (Komplexe) Angeborene Herzfehler mit überwiegendem Rechts-Iinks-Shunt.- 9 Lageanomalien des Herzens (H. Barth).- 10 Anomalien der Koronararterien.- 11 Seltenere angeborene und erworbene Anomalien des Herzens.- 12 Systemerkrankungen mit Herzbeteiligung.- 13 Entzündliche Erkrankungen des Herzens, erworbene Herzfehler.- 14 Herzrhythmusstörungen.- 15 Der plötzliche Säuglingstod.- 16 Spezielle kinderkardiologische Probleme.- 17 Therapie.- 18 Spezielle Probleme herzkranker Patienten.- Kinderkardiologie in Maß und Zahl (A.A. Schmaltz).- Weiterführende Literatur.

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Book SynopsisEntscheidend für eine kompetente Diagnostik mit der Methode der Langzeit-Elektrokardiographie ist fundiertes Wissen über ihre Voraussetzungen, ihre Grenzen und Fehlerquellen sowie über die richtige Bewertung gefundener Rhythmusstörungen.Diese Kenntnisse stellt Ihnen das erfolgreiche Praxisbuch übersichtlich zur Verfügung:* Alle Möglichkeiten von Langzeit-EKG und Langzeit-Blutdruckmessung* Methodik und Klinik* Therapeutische Konzepte und TherapiekontrolleDie Darstellung ist durchgehend am klinischen Problem orientiert und enthält zahlreiche Beispiele, Tabellen, Graphiken und Literaturhinweise.Trade Review"...Die systematische Erarbeitung des Buches ist jedem zu empfehlen, der die Methode einsetzen will. Aber auch der bereits mit ihr Vertraute findet beim Nachschlagen immer wieder Hinweise, die ihm helfen können, auffällige Einzelbefunde richtig einzuordnen." (Anaesthesiologie und Reanimation)Table of Contents1 Historischer Abriß1.- 2 Methodischer Teil.- 2.1 Apparatives Grundkonzept1.- 2.2 Verschiedene Gerätekonzepte1.- 2.2.1 Das Holter-EKG.- 2.2.2 Vollausschrieb des Langzeit-EKG.- 2.2.3 Computerisierte Langzeit-Elektrokardiographie.- 2.2.4 Diskontinuierliche Langzeit-Elektrokardiographie.- 2.3 Anlegen und EKG-Speichern2.- 2.3.1 Anlegen des Langzeit-EKG-Recorders.- 2.3.2 EKG-Speichern.- 2.4 Registrierdauer2.- 2.5 Auswertung2.- 2.5.1 Grundrhythmus und Herzfrequenz.- 2.5.2 Tachykarde Rhythmusstörungen.- 2.5.3 Bradykarde Rhythmus- und Leitungsstörungen.- 2.5.4 Schrittmacherfehlfunktionen1.- 2.5.5 ST-T-Abschnitt2.- 2.5.6 Zuverlässigkeit audiovisueller Auswertung1.- 2.5.7 Zuverlässigkeit computerisierter Auswertung1.- 2.6 Artefaktabgrenzung1.- 2.7 Stellenwert des Belastungs-EKG2.- 2.7.1 Grundlagen und Methodik.- 2.7.2 Bedeutung des Belastungs-EKG für die Arrhythmiediagnostik.- 2.7.3 Vergleich von Belastungs- und Langzeit-EKG in der Arrhythmiediagnostik.- 2.7.4 Vergleich von Belastungs- und Langzeit-EKG in der ST-Strecken-Analyse.- 2.8 Methodische Aspekte der 24-Stunden Blutdruckmessung3.- 3 Klinischer Teil.- 3.1 Häufigkeit und Prognose der Rhythmusstörungen1 bei verschiedenen Personengruppen.- 3.1.1 Gesunde.- 3.1.2 Koronarkranke.- 3.1.3 Patienten mit erworbenen bzw. kongenitalen Herzfehlern3.- 3.1.4 Mitralklappenprolapsträger2.- 3.1.5 Patienten mit Kardiomyopathien2.- 3.1.6 Patienten mit verlängerter QT-Zeit2.- 3.1.7 Patienten mit Synkopen1.- 3.1.8 Patienten mit zerebralen Blutungen1.- 3.2 Rhythmusstörungen vor und zum Zeitpunkt des plötzlichen Herztodes3.- 3.2.1 Patienten.- 3.2.2 Langzeit-EKG-Befunde.- 3.3 Häufigkeit von ST-Streckenveränderungen1.- 3.3.1 Gesunde.- 3.3.2 Koronarkranke.- 3.4 Häufigkeit transitorischer Schrittmacherfehlfunktionen1.- 3.4.1 Schrittmacherindikation und Langzeit-EKG.- 3.4.2 Symptome nach Schrittmacherimplantation.- 3.4.3 Häufigkeit transitorischer Schrittmacherfehlfunktionen.- 3.4.4 Unangemessene Schrittmacherhemmung.- 3.4.5 Sensingdefekt.- 3.4.6 Exit-Block.- 3.4.7 Fehler bei frequenzadaptiver Stimulation.- 3.4.8 Schlußfolgerungen.- 3.5 Klinische Bedeutung der 24-Stunden-Langzeit-Blutdruckmessung3.- 3.5.1 Zirkadiane Rhythmik.- 3.5.2 Normalwerte.- 3.5.3 Praxishypertonie und Praxisnormotonie.- 3.5.4 Fehlender nächtlicher Blutdruckabfall bei sekundärer Hypertonie.- 3.5.5 Antihypertensive Therapie.- 3.5.6 Prognostische Bedeutung der Langzeitblutdruckmessung.- 4 Therapiekontrolle.- 4.1 Spontanvariabilität2.- 4.1.1 Herzfrequenz.- 4.1.2 Rhythmusstörungen.- 4.1.3 ST-Streckenveränderungen.- 4.2 Arrhythmieklassifikation1.- 4.2.1 Hämodynamische Konsequenzen tachykarder Rhythmusstörungen.- 4.2.2 Prognostische Bedeutung tachykarder Rhythmusstörungen.- 4.2.3 Effizienz antiarrhythmischer Behandlung.- 4.3 Kriterien therapeutischer Interventionen2.- 4.4 Langzeit-EKG oder programmierte Stimulation als Therapiekontrolle?2.- 4.4.1 Antiarrhythmische Therapiekontrolle bei asymptomatischen Patienten.- 4.4.2 Antiarrhythmische Therapiekontrolle bei symptomatischen Patienten.- 4.4.3 Vergleich des Langzeit-EKG mit der programmierten Stimulation.- 5 Indikationen zum Langzeit-EKG1.- 5.1 Aussagen der Methoden.- 5.2 Klinische Indikationen.

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Book SynopsisThe Italian Study Group on Cardiomyopathies organized in Florence in April 1997, eight years after the first successful meeting, the second international symposium devoted to "Advances in Cardiomyopathies". In these years exceptional progress has been made in the field of heart muscle diseases, in clinical research as well as in molecular biology, molec- ular genetics., pathophysiology and treatment. Many of these advances were presented and discussed in Florence by a distinguished team of international experts. Hypertrophic cardiomyopathy was addressed in ten papers; in the first one Seidman reported the results obtained by the use of molecular genetic tech- niques which showed that hypertrophic cardiomyopathy is a heterogeneous disorder caused by different mutations of different genes and discussed the clinical role and significance of genetic testing. Original data regarding the natural history and prognosis of symptomatic patients were obtained in the Italian multicentric study (Cecchi, Lazzeroni), while Baroldi discussed the clinico-pathologic spectrum of the disease in severely symptomatic patients treated with heart transplantation. Sudden death in the young (Basso), the identification and management of high risk patients (Elliott), the clinical importance and the problems of detec- tion of ischemia (Camici) were deeply discussed as well as the indications and results of different types of treatment: medical, surgical, DDD pacing (Spirito, Betocchi, Schoendube).Table of ContentsIntroduction: II Florence Meeting on Advances in Cardiomyopathies The Clinical Significance of Genetic Testing in Familial Hypertrophic Cardiomyopathy The Italian Multicentric Study on Hypertrophic Cardiomyopathy: I.Natural History and Clinical Course of Unselected Patients Detection and Clinical Consequences of Myocardial Ischemia and, Reduced Coronary Reserve The Coronary Circulation is Dysfunctional in both Hypertrophied and Non-Hypertrophied Myocardium Hypertrophic Cardiomyopathy and Sudden Death in the Young: a Pathologist's View Identification and Management of High Risk Patients with Hypertrophic Cardiomyopathy The Italian Multicentric Study on Hypertrophic Cardiomyopathy: II. Prognostic Assessment in Symptomatic Patients Medical Treatment of Heart Failure in Hypertrophic Cardiomyopathy DDD Pacing in HCM: State of the Art Indications and Outcome of Cardiac Surgery for Severely Symptomatic Patients with Hypertrophic Obstructive Cardiomyopathy Genetic Basis of Dilated Cardiomyopathy Virus Infection in Cardiomyopathies: Brief Overview, Recent Advances Organ-specific Cardiac Autoantibodies in Dilated Cardiomyopathy: Pathogenetic Implications Inflammatory Cardiomyopathy: Diagnosis and Therapeutical Options Pathophysiologic Role of Coronary Microcirculatory Impairment in Dilated Cardiomyopathy Molecular Biology of Cardiac Failure Dilated Cardiomyopathy: does Etiological Heterogeneity Portend Clinical Heterogeneity? The Natural History of Dilated Cardiomyopathy. The SPIC Registry 1986-1995. Therapeutic Strategies in Dilated Cardiomyopathy: Immunosuppressive Treatment for Inflammatory Dilated Cardiomyopathy (Myocarditis) Prevention of Sudden Death in Patients with Dilated Cardiomyopathy End-Stage Heart Failure and Timing of Heart Transplantation Beta-Blockers for Heart Failure: Practical Issues DDD Pacing in Dilated Cardiomyopathy Cardiomyoplasty: Surgical Therapy for Ischemic and Idiopathic Dilated Cardiomyopathies .

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Book SynopsisThe most salient feature of the infor­ last four chapters of the book evaluate the mation provided by nuclear medicine is its information from an analytical and pathophysiological and functional charac­ statistical point of view. This approach is ter. For adequate experimental or clinical required for correct decision-making. interpretation, such information should This book is therefore the result of necessarily be interpreted alongside the accumulated experience in nuclear cardiology views of the clinical cardiologist, who is with the invaluable cooperation of medical able to apply it to the individual patient. statisticians. It is directed to physicians This approach, which is routine in every­ with an interest in nuclear cardiology, to day clinical practice, reaches its plenitude nuclear medicine specialists wishing to when the whole process is completed and learn the uses and limitations of these an intimate cooperation is established procedures in everyday clinical cardiology, between the nuclear medicine specialist and to cardiologists who feel the need to and the clinical cardiologist. In such understand the rationale and methodology instances, each one of these professionals of the studies which benefit their patients. understands the needs, limits and possi­ We understand that the ultimate reason bilities of the other. for any scientific book is the transmission The present book is the fruit of such of knowledge, and we are fully conscious cooperation. In our hospital, an efficient of the enthusiasm of the authors of the nuclear cardiology team has been made up present text to achieve that aim.Trade Review... about the Spanish edition ... ` I can unreservedly recommend this book to doctors, radiologists and cardiologists working in nuclear medicine and imaging with radionuclides. It is a most useful source of reference ... it will be extremely well received. ' P.J. Ell in European Jrnl of Nuclear Medicine, 19 Table of ContentsForeword; F.M. Domènech-Torné, J. Soler-Soler. Preface; P. Ell. Introduction; J. Candell-Riera, D. Ortega-Alcalde. 1. Physicochemical and technical fundamentals; P. Galofré-Mora. 2. Image processing; D. Ortega-Alcalde. 3. Stress testing; J. Candell-Riera. 4. Myocardial perfusion studies; D. Ortega-Alcalde. 5. Methods for quantifying myocardial perfusion; J. Castell-Conesa. 6. Studies of myocardial damage and viability; M. Fraile. 7. First-pass radionuclide ventriculography; S. Aguadé-Bruix. 8. Gated blood-pool radionuclide ventriculography; D. Ortega-Alcalde. 9. Ventricular volume measurement; J. Castell-Conesa. 10. Parametric images and Fourier's analysis; D. Ortega-Alcalde. 11. Diagnosis of coronary artery disease; J. Candell-Riera. 12. Prognostic evaluation and follow-up of chronic coronary artery disease; J. Candell-Riera. 13. Diagnosis of acute myocardial infarction; J. Cortadellas-Angel. 14. Prognostic evaluation after acute myocardial infarction; A. Rius-Daví. 15. Congenital heart disease; E. Galve. 16. Valvular heart disease; M.P. Tornos-Mas. 17. Cardiomyopathies; J. Candell-Riera. 18. Methods for diagnostic evaluation; J. Rosselló-Urgell. 19. The probability of a correct diagnosis; M. Olona-Cabases. 20. Uses of multiple logistic regression; J. Vagué-Rafart. 21. Cost analysis and decision trees; B.Bermejo-Fraile. Index.

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Book SynopsisThe original series, Advances in Prostaglandin Research, edited by Sultan M. M. Karim, was published by MTP Press in three volumes in 1975 and 1976. A glance at those books illustrates the progress that has been made since then. The thromboxanes were mentioned twice (first publication 1975) and prostacyclin not once (first publication 1976); leukotrienes were only on the horizon. The amazing generation of research data in the last 10-15 years has given new, broad insights into many areas, including asthma, inflammation, renaL cardiovascular and gastrointestinal diseases and in reproduction, and has led in some instances to real clinical benefit. This series, Advances in Eicosanoid Research, reflects the current understanding of prostaglandins, thromboxanes and leukotrienes. The aim is to provide an introductory background to each topic and the most up-to-date information available. Although each book stands alone, the eicosanoids cut across many boundaries in their basic actions; selected chapters from each book in the series will provide illuminating and productive information for all readers which will advance their education and research. In the production of this series, I must acknowledge with pleasure my collaboration with editors and authors and the patient endeavours of Dr Michael Brewis and the staff at MTP Press.Trade Review`... adds considerably to the attractiveness of this volume. This volume can be recommended as a good reference book for medical students and graduates of medical school.' Eicosanoids, 2/63-64, 1989 Table of Contents1 Arachidonic acid metabolism and platelet function.- 2 Renal arachidonic acid metabolism.- 3 Arachidonic acid metabolism in renal disease.- 4 Eicosanoids and pulmonary injury.- 5 Eicosanoids in sepsis and its sequelae.- 6 Eicosanoids in myocardial ischaemia and injury.- 7 Prostanoids in clinical and experimental hypertension.- 8 Prostacyclin receptors.- 9 Platelet and vascular smooth muscle thromboxane A2/prostaglandin H2 receptors.- 10 Mechanisms of action of prostaglandin E2 and prostaglandin F2?: PGE and PGF? receptors.

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Book SynopsisIn recent years, the understanding of the pathophysiological processes of atherosclerosis, a chronic inflammatory disease of the vessel wall being the leading cause for mortality in industrial countries, has tremendously increased. The feasibility of translating such knowledge to novel therapeutic approaches is currently being explored at various levels. This book highlights advances in atherosclerosis and links these to relevant therapeutic strategies. It compiles and details cutting-edge research in cardiovascular medicine from internationally renowned authors. Table of ContentsNovel approaches in treatment of atherosclerosis. Chemokines as therapeutic targets of atherosclerosis. MIF antagonism as a therapeutic approach to atherosclerosis. Peptide-based vaccination strategies to promote Treg- or antibody-mediated atheroprotection. Modulation of prostanoids in the treatment of atherosclerosis. Stabilization of mast cells for taming vulnerable plaques. HDL, ABC transporters, and cholesterol efflux as therapeutic targets in atherosclerosis. Role of selective phospholipase A2 inhibition in the treatment of atherosclerosis. Modulation of the rennin-angiotensin system in atherosclerosis. Role of matrix metalloproteases as targets for the prevention of atherosclerosis. Probucol-derivates in the treatment of atherosclerosis. Interference with apoptosis and ER stress in the treatment of atherosclerosis. MicroRNAs in the pathogenesis and therapy of atherosclerotic vascular disease. Neutrophils and their granule proteins in the treatment of atherosclerosis. Platelets in the treatment of atherosclerosis. Costimulatory molecules in the treatment of atherosclerosis.

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Book SynopsisNotre Dame English professor emeritus William O'Rourke recounts his heart attack and the experiences he had during recuperation. From the resulting heightened awareness of his mortality, O'Rourke asks us to change behaviors and to pay attention to our health.Trade Review"O'Rourke' s book and its long description of having a heart attack may scare the bejesus out of you, but it certainly sheds a lot of light on the subject. He's writing about what he knows and he knows a lot. His book is full of life—full of heart—and necessary reading for anyone who's ever thought twice about the tough organ that keeps us alive." —Malachy McCourt, author of A Monk Swimming and Bush Lies in State"The story of William O'Rourks's heart attack is as compelling as a thriller because it is a thriller. As always, O'Rourke's prose is crisp, witty, and wholly original. The chronicle of his recovery demystifies a frightening illness, leaving a reader enlightened and, unexpectedly, cheered." —Valerie Sayers, author of Brian Fever and Due East"In the first few pages of William O'Rourke's gripping book I learned what it feels like to have a heart attack and how the press or pleasure of daily events can keep us postponing the visit to the Emergency Room. Now, I tell myself, I'll be prepared even in the middle of the night or at a sports event. Thanks to my husband's many years of MS, I did have an idea of how important a good doctor, a ready wife or husband, an eagle eye for proceedings, and even chance can be in determining one's future—but the uninitiated in such mysteries will find On Having A Heart Attack to be full of first person insights. Besides, if it has already happened to O'Rourke, maybe it won't happen to his readers!" —Maggie Strong, author of Mainstay: For the Well Spouse of the Chronically Ill"Despite its somber subject, the book is as gripping as fiction, full of drama, conflict, and angst. . . . While convalescing, O'Rourke read all he could find in the literature of MI (myocardial infarction) but met with a singular lack of comprehensive accounts of the physical and psychic experience itself, and how it affects the family and friends of the patient. This he supplies with wry wit and unsparing rue, distillations of the novelist's second nature-attentiveness in calamity, and richness of recall." —Provincetown Arts"For anyone who has ever had a serious medical crisis, or been close to someone who has, William O'Rourke's book is essential reading. O'Rourke takes us on a fascinating, compelling journey into the literal and figurative heart of a gloriously full and fragile life. He illuminates much about our vitality and our mortality, and the ways in which fortune and modern medicine can collaborate in our individual and collective fates. This is a rich tale by a splendid storyteller—a most unforgettable, informative, and deeply moving memoir of one man's struggles and triumphs." —Jay Neugeboren, author of Open Heart: A Patient's Story of Life-Saving Medicine and Life-Giving Friendship"A must-read for practicing physicians, cardiologists, nurses, physician assistants, and the general public. . . . [T]his is an excellent, thoroughly informed book. It will be helpful for recuperating patients and their families and for anyone concerned about heart disease." —Journal of the American Medical Association“This very personal account of exactly what it was like to have a heart attack, to notice medical personnel somewhat hesitant to treat him until they saw his insurance card, to contemplate the possibility of dying before his son turned two, and to make lifestyle changes to lower the risk of a second attack is frightening, moving and sometimes funny.” —Booklist“Books about heart attacks and heart disease abound, mostly authored by health care professionals who specialize in the treatment of heart patients or work as nutritionists. Books written by actual survivors of an MI . . . are rare and a book, such as this, written by someone who is both a survivor and a noted author, is certainly the exception . . . this memoir is much more than just a self-help book. The author examines the many personal thoughts the patient stricken by a heart attack unavoidably encounters. . . . It is a book that doctors and nurses should read and learn from, and one that all those should read who are potentially threatened with heart disease.” —Third Coast

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Book SynopsisProvides an illustrated account of changes in our perception of what the heart does and what it means. This book explores the symbolic significance of the heart in ancient Egypt, China, India and Greece, its role in Aztec ceremony and its place in the medieval world. It considers the centrality of the heart in Christianity and other religions.Table of ContentsLouisa Young: The Human Heart; Francis Wells: The Renaissance Heart; Emily Jo Sargent: The Sacred Heart; Fay Bound Alberti: The Emotional Heart; Ayesha Nathoo: The Transplanted Heart; Melissa Larner: The Healing Heart; Ted Bianco: The Animal Heart; Michael Bracewell: The Broken Heart; Jon Turney: The Future Heart.

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Book SynopsisTechnical Aspects.- Electrocardiographic Interpretation.- Presenting ECG Holter Data.- Clinical Applications.- Other ECG Recording Systems.- ECG Holter and Implanted Cardioverter Defibrillators.- ECG Report Example.- Conclusion.Table of ContentsTechnical Aspects.- Electrocardiographic Interpretation.- Presenting ECG Holter Data.- Clinical Applications.- Other ECG Recording Systems.- ECG Holter and Implanted Cardioverter Defibrillators.- ECG Report Example.- Conclusion.

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Book SynopsisThe author addresses the different stages a patient may experience prior to receiving a VAD (Ventricular Assist Device, beginning with the various reasons for gaining venous access and specific challenges this may present e.g. age, acute and chronic disease processes, anatomical anomalies and cosmetic issues.Table of ContentsChapter 1: The History of Central Venous Access. Chapter 2: Applied anatomy of the central veins. Chapter 3: Patient Examination and assessment: choice of devices. Chapter 4: Catheter design and materials. Chapter 5: Cannulation of the Jugular Veins. Chapter 6: Practical Venous Access via the Femoral Vein. Chapter 7: Central venous access via the subclavian and axillary veins. Chapter 8: Peripherally Inserted Central Catheters. Chapter 9: Ultrasound Guided Venous Access. Chapter 10: The role of diagnostic and interventional radiology in the placement and management of central venous catheters. Chapter 11: Problems and Practical Solutions during Insertion of Catheters. Chapter 12: Complications of central venous access. Chapter 13: The Pathogenisis and Prevention of Intravascular Catheter Related Infections. Chapter 14: Aftercare and Management of Central Venous Access Devices. Chapter 15: Removal of central venous access devices. References. Index.

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Book SynopsisTable of ContentsNotes on Contributors, xi Foreword, xv Preface, xvii Abbreviations, xix About the Companion Website, xxi Part I Congenital Heart Disease in the Adult Case 1 Aneurysmal Aorto–Left Ventricular Tunnel and Bicuspid Aortic Valve with Severe Stenosis, 3Fanxia Meng, Bo Zhang, Nan Xu, and Jing Ping Sun Case 2 Anomalous Origin of the Left Coronary Artery from the Pulmonary Trunk, 9Weihua Wu and Jing Ping Sun Case 3 Anomalous Origin of Right Coronary Artery, 15Kevin Ka]Ho Kam, Jing Ping Sun, and Xing Sheng Yang Case 4 Interrupted Aortic Arch associated with Aortopulmonary Window, 19Yali Xu and Jing Ping Sun Case 5 Congenitally Corrected Transposition of the Great Arteries, 23Ming-Ming Sim and Jing Ping Sun Case 6 Coronary Fistula, 29Fanxia Meng, Jing Ping Sun, Ming Chen, and Lei Zhang Case 7 Crista Terminalis Bridge Mimicking Right Atrial Mass, 35Jing Ping Sun, Alex Pui]Wai Lee, and Xing Sheng Yang Case 8 A Criss]cross Heart with Double Outlet Right Ventricle, 39Lianghua Xia, Bo Zhang, Fanxia Meng, and Jing Ping Sun Case 9 Double]Chambered Right Ventricle with Ventricular Septal Defect, 45Lei Zhang, Fanxia Meng, Ming Chen, and Jing Ping Sun Case 10 Isolated Double]Orifice Mitral Valve, 51Jing Ping Sun Case 11 The Gerbode Defect: A Ventriculo]Atrial Defect, 55Xing Sheng Yang and Jing Ping Sun Case 12 Intralobar Pulmonary Sequestration, 61Lei Zhang and Jing Ping Sun Case 13 Partial Anomalous Pulmonary Venous Connection with Secundum Atrial Septal Defect, 67Liu Chen, Hong Tang, Yuan Feng, and Jing Ping Sun Case 14 Pulmonary Arteriovenous Malformation, 73Jing Ping Sun, Xing Sheng Yang, and Ka]Tak Wong Case 15 Right Pulmonary Agenesis associated with Congenital Heart Diseases, 79Junli Hu, Guiling Sui, and Jing Ping Sun Case 16 Compressive Giant Right Atrial Diverticulum, 83Guozhen Yuan, Shaochun Wang, Bryan P. Yan, and Jing Ping Sun Case 17 Shone’s Syndrome, 87Weihua Wu, Bryan P. Yan, and Jing Ping Sun Case 18 Subaortic Membrane in the Adult, 95Jing Ping Sun and Alex Pui]Wai Lee Case 19 Supracardiac Total Anomalous Pulmonary Venous Connection, 101Fanxia Meng, Ming Chen, and Jing Ping Sun Case 20 Tricuspid Atresia, 107Jing Ping Sun Case 21 Isolated Congenital Tricuspid Valve Dysplasia in a 38]year]old Adult, 111Ligang Fang and Jing Ping Sun Case 22 Unroofed Coronary Sinus Defect, 115Ran Guo, Jing Ping Sun, and Alex Pui]Wai Lee Part II Artery Disease Case 23 Acute Aortic Regurgitation caused by Spontaneous Aortic Valve Rupture, 123Li]Tan Yang, Ping]Yen Liu, Cheng]Han Lee, and Wei]Chuan Tsai Case 24 Bicuspid Aortic Valve Complicated by Pseudo]aneurysm of Aortic Root Abscesses, 129Shuran Huang, Zhanguo Sun, and Jing Ping Sun Case 25 Coronary Artery Vasculitis in Patient with Systemic Lupus Erythematosus, 135Ligang Fan, Yining Wang, and Jing Ping Sun Case 26 Aortic Dissection, 141Jing Ping Sun and Xing Sheng Yang Case 27 Large Thrombus in Giant Unruptured Noncoronary Sinus of Valsalva Aneurysm, 149Weihua Wu and Jing Ping Sun Case 28 Isolated Pulmonary Vasculitis, 155Hongmei Xia, Yuanqing Cai, and Jing Ping Sun Case 29 Giant Left Ventricular Pseudoaneurysm, 161Liu Chen, Hong Tang, Yuan Feng, and Jing Ping Sun Case 30 Salmonela Aortitis: A Rare Cause of Fever and Back Pain in the Elderly, 167Jen]Li Looi, Alex Pui]Wai Lee, and Jing Ping Sun Case 31 Subepicardial Aneurysm of Left Ventricle: A Rare Complication of Acute Myocardial Infarction, 173Ying Zheng, Zhiqing Qiao, Xuedong Shen, and Ben He Case 32 Coronary Artery Disease and Systemic Vasculitis, 179Ligang Fang, Jing Ping Sun, and Yining Wang Part III Cardiac Mass Case 33 Primary Cardiac Angiosarcoma in Left Atrium, 187Hongjun Wang, Junli Hu, Shaochun Wang, and Jing Ping Sun Case 34 Atypical Left]Atrial Papillary Fibroelastoma, 193Kevin Ka]Ho Kam, Alex Pui]Wai Lee, and Jing Ping Sun Case 35 Cardiac Lipoma with Ventricular Arrhythmias, 197Litong Qi, Ying Yang, Yong Huo, and Jing Ping Sun Case 36 Primary Cardiac Pheochromocytoma, 201Ligang Fang, Jing Ping Sun, and Yining Wang Case 37 Cardiac Rhabdomyosarcoma of the Left Atrium, 205Lan Ma, Ming Chen, and Jing Ping Sun Case 38 Unusual Cardiac Fibroelastoma, 211Fanxia Meng, Ming Chen, and Jing Ping Sun Case 39 Pulmonary and Cardiac Inflammatory Myofibroblastic Tumor, 217Yong Jiang, Hao Wang, and Jing Ping Sun Case 40 Intravenous Leiomyomatosis with Cardiac Metastases, 221Ligang Fang, Jing Ping Sun, and Yining Wang Case 41 Intramural Left Atrial Hematoma Complicating Catheter Ablation for Atrial Fibrillation, 225Jen]Li Looi, Alex Pui]Wai Lee, and Jing Ping Sun Case 42 Primary Cardiac Lymphoma: Two Rare Cases, 229Yi Liu, Min Xu, Bo Zhang, and Jing Ping Sun Case 43 Mass in Left Atrium and Appendage, 235Jing Ping Sun, Fanxia Meng, Xing Sheng Yang, Alex Pui]Wai Lee, and Bo Zhang Case 44 Metastatic Cardiac Lymphoma, 241Jing Ping Sun, Xing Sheng Yang, and Alex Pui]Wai Lee Case 45 Metastatic Renal Carcinoma in Inferior Vena Cava, 245Jing Ping Sun and Jen]Li Looi Case 46 Pericardial Metastasis Mass from Thyroid Carcinoma, 249Changchun Hao and Jing Ping Sun Case 47 Spindle Cell Sarcoma: A Rare Case of Multicardiac Chamber Mass, 253Chengzheng Zhang, Junli Hu, Shaochun Wang, and Jing Ping Sun Part IV Cardiomyopathy and Myocarditis Case 48 Fulminant Myocarditis, 259Lei Zhang, Jingjin Wang, and Jing Ping Sun Case 49 Cardiac Amyloidosis, 267Jing Ping Sun, Xing Sheng Yang, Bryan P. Yan, and Ka]Tak Wong Case 50 Hypertrophic Cardiomyopathy with Apical Aneurysm, 281Jing Ping Sun, Xing Sheng Yang, and Ka]Tak Wong Case 51 Arrythmogenic Right Ventricular Dysplasia, 287Doris T. Chan, Anna K. Y. Chan, and Jing Ping Sun Case 52 Danon Disease, 293Ligang Fang and Jing Ping Sun Case 53 Acute Eosinophilic Myocarditis, 299Xianda Ni and Jing Ping Sun Case 54 Noncompaction Cardiomyopathy with Apical Aneurysm, 305Xianda Ni, Xing Sheng Yang, and Jing Ping Sun Part V Diversification Case 55 A Fistula between Aortic Pseudoaneurysm and Right Atrium, 313Ligang Fang and Jing Ping Sun Case 56 Dual Aortic and Mitral Valve Aneurysms in a Patient with Infective Endocarditis, 317Weihua Wu, Lan Ma, Xing Sheng Yang, Bryan P. Yan, and Jing Ping Sun Case 57 Intracardiac Thrombus in Behcet’s Disease, 321Ligang Fang, Jing Ping Sun, and Yining Wang Case 58 Cardiac Hydatid Disease, 325Ligang Fang, Jing Ping Sun, and Yining Wang Case 59 Diagnosis of Constrictive Pericarditis with Multimodality Imaging, 329Alex Pui]Wai Lee and Jing Ping Sun Case 60 Inverted Left]Atrial Appendage, 333Haiping Zhang and Jing Ping Sun Case 61 Inferior Vena Stent Fracture and Multiple Heart Injuries caused by Migration, 337Ligang Fang, Yining Wang, and Jing Ping Sun Case 62 Anterior Mitral Valve Aneurysm: A Rare Complication of Aortic Valve Endocarditis, 341Jinchuan Yan, Fen Zhang, Yi Liang, and Jing Ping Sun Index, 345

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Book SynopsisQuality in Laboratory Hemostasis and Thrombosis Second Edition Edited by Steve Kitchen, Clinical Scientist, Sheffield Haemophilia and Thrombosis Centre, Royal Hallamshire Hospital and Scientific Director, UK National External Quality Assessment Scheme (FQAS) for Blood Coagulation, Scientific Director, WHO and WFH International External Quality Assessment Programs for Blood Coagulation, Sheffield, UK John D Olson, Professor and Vice Chair for Clinical Affairs, Department of Pathology, University of Texas Health Sciences Centre, San Antonio, Texas, USA F. Eric Preston, Emeritus Professsor of Haematology, University of Sheffield and Director, WHO and WFH International External Quality Assessment Programs for Blood Coagulations, Sheffield, UK The hemostasis laboratory has a vital role in the diagnosis and management of patients with familial and acquired hemorrhagic and thrombotic disorders. Rapid changes in the numbeTable of ContentsContributors, vii Foreword, x Preface, xii Steve Kitchen, John D. Olson, & F. Eric Preston Part 1: General Quality Program 1 General quality planning in the hemostasis laboratory, 3 John D. Olson 2 Hemostasis test validation, performance, and reference intervals: international recommendations and guidelines, 12 Richard A. Marlar 3 Causes of errors in medical laboratories, 22 Giuseppe Lippi & Emmanuel J. Favaloro 4 International standards in hemostasis, 32 Trevor W. Barrowcliffe & Anthony R. Hubbard 5 Sample integrity and preanalytical variables, 45 Dorothy (Adcock) Funk 6 Internal quality control in the hemostasis laboratory, 57 Steve Kitchen, F. Eric Preston, & John D. Olson 7 External quality assessment in hemostasis: its importance and significance, 65 F. Eric Preston, Steve Kitchen, & Alok Srivastava 8 The unique challenges of hemostatic testing in children, 77 M. Patricia Massicotte, Mary E. Bauman, Vanessa Chan, & Anthony K.C. Chan Part 2: Quality in Coagulation Testing 9 Initial evaluation of hemostasis: reagent and method selection, 95 Wayne L. Chandler 10 Assay of factor VIII and other clotting factors, 105 Steve Kitchen & F. Eric Preston 11 Application of molecular genetics to the investigation of inherited bleeding disorders, 115 Stefan Lethagen, Morten Dunø, & Lars Bo Nielsen 12 Detecting and quantifying acquired functional inhibitors in hemostasis, 124 Bert Verbruggen, Myriam Dardikh, & Britta Laros-van Gorkom 13 Standardization of d-dimer testing, 136 Guido Reber & Philippe de Moerloose 14 Point-of-care testing in hemostasis, 147 Chris Gardiner, Dianne Kitchen, Samuel Machin, & Ian Mackie Part 3: Quality in Testing for Platelet Function and von Willebrand Disease 15 Diagnostic assessment of platelet function, 159 Paquita Nurden, Alan Nurden, & Martine Jandrot-Perrus 16 Laboratory evaluation of heparin-induced thrombocytopenia, 174 Theodore (Ted) E. Warkentin & Jane C. Moore 17 Laboratory evaluation of von Willebrand disease: phenotypic analysis, 192 Emmanuel J. Favaloro 18 Laboratory analysis of von Willebrand disease: molecular analysis, 204 Anne C. Goodeve & Ian R. Peake Part 4: Quality in Thrombophilia Testing and Monitoring Anticoagulation 19 Quality issues in heritable thrombophilia testing, 219 Isobel D. Walker & Ian Jennings 20 Evaluation of antiphospholipid antibodies, 233 Michael Greaves 21 Monitoring heparin therapy, 244 Marilyn Johnston 22 Monitoring oral anticoagulant therapy with vitamin K antagonists, 253 Armando Tripodi 23 Monitoring new anticoagulants, 264 Elaine Gray & Trevor W. Barrowcliffe Index, 273

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Book SynopsisWritten by leading experts in the field, Cardiovascular Diseases and Health in the Older Patient covers the epidemiology, pathophysiology and management of cardiovascular disease in the older patient.Trade Review“Because it specifically addresses cardiovascular disease in the elderly this is a useful addition to the literature.” (Doody's, 9 August 2013)Table of ContentsList of Contributors, vii Foreword, ix Introduction, xi 1 Epidemiology of Heart Disease, 1 Ahmed H. Abdelhafiz 2 Cardiac Ageing and Systemic Disorders, 29 David J. Stott and Terence J. Quinn 3 Hypertension, 44 Anthony S. Wierzbicki and Adie Viljoen 4 Lipid Management, 68 Adie Viljoen and Anthony S. Wierzbicki 5 Arrhythmias, 90 Abhay Bajpai and A. John Camm 6 Hypotension, 135 Suraj Alakkassery 7 Ischaemic Heart Disease, 152 Wilbert S. Aronow 8 Heart Failure, 172 Michael W. Rich 9 Cardiac Surgery, 202 Ulrich O. von Oppell and Adam Szafranek 10 Cardiac Rehabilitation, 234 Niccol`o Marchionni, Francesco Fattirolli, Francesco Orso, Marco Baccini, Lucio A. Rinaldi and Giulio Masotti 11 Acute Stroke Care and Management of Carotid Artery Stenosis, 261 David Doig and Martin M. Brown 12 Stroke Rehabilitation, 299 Lalit Kalra 13 Communication Disorders and Dysphagia, 329 Pamela M. Enderby 14 Peripheral Arterial Disease, 345 Leocadio Rodr´ýguez-Ma ˜ nas, Marta Castro Rodr´ýguez and Cristina Alonso Bouz´on 15 Venous Thromboembolism, 366 Gordon D.O. Lowe 16 Planning Cardiovascular Investigations and Management of Older People, 376 Jennifer K. Harrison, Terence J. Quinn and David J. Stott Index, 395

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Book SynopsisThis title is part of UC Press's Voices Revived program, which commemorates University of California Press's mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1966.

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