Biomedical engineering / Medical engineering Books
Taylor & Francis Ltd Biology for Engineers Second Edition
Book SynopsisBiology is a critical application area for engineering analysis and design, and students in engineering programs as well as ecologists and environmentalists must be well-versed in the fundamentals of biology as they relate to their field. Biology for Engineers, Second Edition is an introductory text that minimizes unnecessary memorization of connections and classifications and instead emphasizes concepts, technology, and the utilization of living things. Whether students are headed toward a bio-related engineering degree or one of the more traditional majors, biology is so important that all engineering students should know how living things work and act. Emphasizing the ever-present interactions between a biological unit and its physical, chemical, and biological environments, the book provides ample instruction on the basics of physics, chemistry, mathematics, and engineering through a systems approach. It brings together all the concepts one needs to understand the role ofTable of ContentsIntroduction. Science and Engineering. Scientific Method. Mathematical Modeling. Biological Engineering. Expectations for Biological Engineers. About Predictions. About This Book. Questions. Principles from the Sciences. Principles of Physics. Effort and Flow Variables. Balances. States of Matter. Equivalence of Work and Energy. Free Energy. Disorder and Entropy. Heat Transfer. Movement of Materials. Fluid Mechanics. Solid Mechanics. Electricity. Temperature Effects. Questions. Principles of Chemistry. Chemical Equilibrium. Acids and Bases. Reaction Rates. Carbon Chemistry. Physical Chemistry in Water. Protein Folding. Shape Effects and Enzymes. Energy-Rich Compounds. Questions. Principles of Mathematics and Engineering Sciences. Control Systems. Principles of Biology. Questions. Responses of Living Systems. Biological Responses in Context (BRIC). Questions. Scaling Factors. Allometric Relationships. Questions. Utilizing Living Systems. Biological Engineering Solutions.
£135.00
Taylor & Francis Ltd Practical Biomedical Signal Analysis Using MATLAB
Book SynopsisCovering the latest cutting-edge techniques in biomedical signal processing while presenting a coherent treatment of various signal processing methods and applications, this second edition of Practical Biomedical Signal Analysis Using MATLAB also offers practical guidance on which procedures are appropriate for a given task and different types of data.It begins by describing signal analysis techniquesincluding the newest and most advanced methods in the fieldin an easy and accessible way, illustrating them with Live Script demos. MATLAB routines are listed when available, and freely available software is discussed where appropriate. The book concludes by exploring the applications of the methods to a broad range of biomedical signals while highlighting common problems encountered in practice.These chapters have been updated throughout and include new sections on multiple channel analysis and connectivity measures, phase-amplitude analysis, functionTable of Contents1. A Short Introduction to Matlab. 2. Introductory Concepts. 3. Single Channel (Univariate) Signal. 4. Multiple Channels (Multivariate) Signals 5. Application to Biomedical Signals.
£130.06
Taylor & Francis Ltd InVitro and InVivo Tools in Drug Delivery
Book SynopsisThis book covers the essentials of drug delivery research and provides a unique forum for scientific experimental methods that are exclusively focused by the in-vitro, ex-vivo, and in-vivo methodologies of drug delivery research and felicitates translational research. The book includes recent and novel approaches in evaluation methods of transdermal, nasal, ocular, oral and intraoral, gastro-retentive, colon-targeted, and brain-targeted drug delivery systems. Providing up to date and comprehensive information, this text is invaluable to students, teachers, scientists, and others employed in the field of drug delivery. Table of Contents1. In-Vitro and In-Vivo Tools in Emerging Drug Delivery Scenario: Challenges and Updates 2. Intraoral and Peroral Drug Delivery Systems 3. Transdermal Drug Delivery Systems 4. Nasal and Pulmonary Drug Delivery Systems 5. Ocular Drug Delivery Systems 6. Gastroretentive Drug Delivery Systems 7. Colon Targeted Drug Delivery Systems 8. Brain Targeted Drug Delivery Systems 9. Parenteral Drug Delivery Systems Appendix: Characterization Parameter and Common Characterization Tools
£165.00
Taylor & Francis Inc Biomedical Signal and Image Processing
Book SynopsisFirst published in 2005, Biomedical Signal and Image Processing received wide and welcome reception from universities and industry research institutions alike, offering detailed, yet accessible information at the reference, upper undergraduate, and first year graduate level. Retaining all of the quality and precision of the first edition, Biomedical Signal and Image Processing, Second Edition offers a number of revisions and improvements to provide the most up-to-date reference available on the fundamental signal and image processing techniques that are used to process biomedical information. Addressing the application of standard and novel processing techniques to some of today's principle biomedical signals and images over three sections, the book begins with an introduction to digital signal and image processing, including Fourier transform, image filtering, edge detection, and wavelet transform. The second section investigates specifically biomedicaTrade Review"This is a great book, ideal for a biomedical signal and image processing course…. a great introduction to the topic, while it also includes advanced topics in the field for graduate courses. … a great collection of topics [including] introduction to signal and image processing, advanced signal processing techniques, physiology and specific signal processing techniques used for various biomedical signals, an introduction to medical image formation, and advanced topics on medical image processing. This is a great book, highly recommended to any research and educator in this field."—Purang Abolmaesumi, Department of Electrical Engineering, University of British Columbia, Vancouver, Canada"I am not aware of a book that covers both biomedical image processing and biomedical signal processing. There are a large number of books that focus on the physics of biomedical imaging. This book however, balances the coverage of physics of biomedical imaging with biomedical image processing. … I was impressed by how clearly the concepts are explained. The authors’ ability to introduce concepts at the level appropriate for senior undergraduate or graduate level students is impressive. … programming questions at the end of the chapter that will give the reader the opportunity to try out the signal processing techniques introduced in the chapter. Also, sample signals are included on the accompanying CD. … I would definitely use this book as my textbook in a biomedical signal-processing course."—Shahram Shirani, McMaster University, Hamilton, Ontario, Canada"… an excellent bridge between the physiological significance of the methods, and the underlying mathematics. … covers a broad range of biomedical problems. … clear, well written, and easy to follow. … this is an excellent course textbook, and also an excellent reference book for professionals."—Dr. Kristian Sandberg, Computational Solutions, Inc., Boulder, Colorado, USA"This is a great book, ideal for a biomedical signal and image processing course…. a great introduction to the topic, while it also includes advanced topics in the field for graduate courses. … a great collection of topics [including] introduction to signal and image processing, advanced signal processing techniques, physiology and specific signal processing techniques used for various biomedical signals, an introduction to medical image formation, and advanced topics on medical image processing. This is a great book, highly recommended to any research and educator in this field."—Purang Abolmaesumi, Department of Electrical Engineering, University of British Columbia, Vancouver, Canada"I am not aware of a book that covers both biomedical image processing and biomedical signal processing. There are a large number of books that focus on the physics of biomedical imaging. This book however, balances the coverage of physics of biomedical imaging with biomedical image processing. … I was impressed by how clearly the concepts are explained. The authors’ ability to introduce concepts at the level appropriate for senior undergraduate or graduate level students is impressive. … programming questions at the end of the chapter that will give the reader the opportunity to try out the signal processing techniques introduced in the chapter. Also, sample signals are included on the accompanying CD. … I would definitely use this book as my textbook in a biomedical signal-processing course."—Shahram Shirani, McMaster University, Hamilton, Ontario, Canada"… an excellent bridge between the physiological significance of the methods, and the underlying mathematics. … covers a broad range of biomedical problems. … clear, well written, and easy to follow. … this is an excellent course textbook, and also an excellent reference book for professionals."—Dr. Kristian Sandberg, Computational Solutions, Inc., Boulder, Colorado, USATable of ContentsIntroduction To Digital Signal And Image Processing: Signals and Biomedical Signal Processing. Fourier Transform. Image Filtering, Enhancement, and Restoration. Edge Detection and Segmentation of Images. Wavelet Transform. Other Signal and Image Processing Methods. Clustering and Classification. Processing Of Biomedical Signals: Electrical Activities of Cell. Electrocardiogram. Electroencephalogram. Electromyogram. Other Biomedical Signals. Processing Of Biomedical Images: Principles of Computed Tomography. X-Ray Imaging and Computed Tomography. Magnetic Resonance Imaging. Ultrasound Imaging. Positron Emission Tomography. Other Biomedical Imaging Techniques. Related Titles.
£135.00
Taylor & Francis Ltd Clarks Procedures in Diagnostic Imaging
Book SynopsisBringing together conventional contrast media studies, computed tomography, ultrasound, magnetic resonance imaging, radionuclide imaging including hybrid imaging using SPECT-CT and PET-CT, DXA studies and digital interventional procedures into one volume, this definitive book is the essential source of information on the use and application of these imaging modalities in radiography. Taking a systemic anatomical approach, carefully designed to be clear and consistent throughout and mirroring that in the popular and established textbook Clarkâs Positioning in Radiography, each chapter is highly illustrated and contains sections detailing anatomy, pathologic considerations, procedure methodology, and an evaluation of recommended imaging modalities.Reflecting the latest clinical imaging pathways and referral guidelines including IR(ME)R 2017, the Map of Medicine and RCR iRefer (8E), Clarkâs Diagnostic Imaging Procedures will quickly become established as the standard textbook for students of radiography and radiographer assistant trainees and an invaluable desk reference for practising radiologists. Trade Review"This book is useful for under and postgraduate radiographic students when investigating alternative diagnostic investigations other than radiography. It is useful in clinical practice as a reference for providing advice on what gold standard imaging/investigations can be utilised in a patient’s diagnostic pathway." -RAD Magazine Table of ContentsPreface Authors and contributors Acknowledgements Origin of Clark’s textbooks Abbreviations Chapter 1 Introduction Chapter 2 Contrast enhancement agents and radiopharmaceuticals Chapter 3 Musculoskeletal system Chapter 4 Respiratory system Chapter 5 Gastrointestinal tract and salivary glandsChapter 6 Liver and biliary system, pancreas and spleen Chapter 7 Urinary system Chapter 8 Reproductive system Chapter 9 Cardiovascular system Chapter 10 Endocrine system Chapter 11 Central nervous system Chapter 12 Breast imaging Chapter 13 Miscellaneous procedures Index
£175.00
SLACK Incorporated Lower-Limb Prosthetics and Orthotics: Clinical Concepts
Book SynopsisLower-Limb Prosthetics and Orthotics: Clinical Concepts is a comprehensive overview of lower-limb prosthetics and orthotics, covering normal and pathological gait, lower-limb biomechanics, clinical applications, as well as prosthetic and orthotic designs and components.Joan Edelstein and Alex Moroz have written Lower-Limb Prosthetics and Orthotics with the clinician’s perspective in mind. Clinical management is incorporated throughout the text, including basic surgical concepts, postoperative management, preprosthetic care, and training in the use of devices. Additionally, this text incorporates unique features relevant to physicians such as prescription writing and prosthetic and orthotic construction and modification, as well as, the latest research regarding energy consumption and long-term utilization of prostheses.Chapters Include: Orthotics in neuromuscular diseases Orthotics in pediatrics Functional expectations Gait and activities training Transtibial and transfemoral prostheses and components Transtibial and transfemoral biomechanics, evaluation, and gait analysis Disarticulations and Bilateral Amputations With over 150 line drawings and photographs to supplement the text, Lower-Limb Prosthetics and Orthotics: Clinical Concepts is ideal for clinicians in the fields of physical medicine and rehabilitation, orthopedics, vascular surgery, physical therapy and occupational therapy.Trade ReviewThe strength of this text lies in its truly comprehensible coverage of lower-limb considerations in P&O, with a focus on breadth rather than depth. The authors’ ability to condense this material into a text less than 200 pages long is admirable. Further, the text of the book is well supported by clear and current photographs and illustrations." — Phil Stevens, Med, CPO, FAAOP, American Academy of Orthotists & Prosthetists"This is an excellent resource for clinicians in training. I would definitely have enjoyed using it during my residency training. It is also a good reference for practicing clinicians." — Leslie K. Rydberg, MD, Rehabilitation Institute of Chicago, Doody Enterprises, Inc.“In summary the book includes many important factors in the rehabilitation of lower limb amputees and would be a useful addition to libraries.” — Louise Johnson, PhysiotherapyTable of Contents DedicationAcknowledgmentsAbout the AuthorsContributing AuthorsPreface Chapter 1 Normal Gait Chapter 2 Early Management Richard A. Frieden, MD Chapter 3 Transtibial Prostheses Chapter 4 Transtibial Biomechanics Chapter 5 Transtibial Static Evaluation Chapter 6 Transtibial Gait Analysis Chapter 7 Transfemoral Prostheses Chapter 8 Transfemoral Biomechanics Chapter 9 Transfemoral Static Evaluation Chapter 10 Transfemoral Gait Analysis Chapter 11 Partial Foot Amputations and Prostheses Chapter 12 Knee and Hip Disarticulations and Prostheses Chapter 13 Bilateral Amputations and Prostheses Chapter 14 Prosthetic Gait and Activities Training Chapter 15 Lifelong Management of Older Patients Richard A. Frieden, MD Chapter 16 Prosthetic Functional Outcomes Chapter 17 Orthotic Principles Chapter 18 Shoes and Foot Orthoses Chapter 19 Ankle-Foot Orthoses Chapter 20 Knee-Ankle-Foot Orthoses Chapter 21 Hip-Knee-Ankle-Foot and Higher Orthoses Chapter 22 Orthotic Static Evaluation Chapter 23 Pathological Gait Analysis Chapter 24 Orthotic Functional Outcomes Chapter 25 Orthotics in Management of Musculoskeletal and Neuromuscular Disorders Chapter 26 Pediatric Prosthetics and Orthotics Joan T. Gold, MD and Joan E. Edelstein, MA, PT, FISPO, CPed Financial Disclosures Index
£86.70
Cambridge University Press Chemical Wave Transmission in Nerve
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£35.14
Cambridge University Press An Introduction to Modeling of Transport Processes
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£94.04
Cambridge University Press SulphateReducing Bacteria
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£59.22
Cambridge University Press Pathway Analysis and Optimization in Metabolic Engineering
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£35.14
Cambridge University Press Lung Mechanics An Inverse Modeling Approach
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£89.29
Cambridge University Press Computerized Data Acquisition and Analysis for the Life Sciences
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£110.20
Cambridge University Press Computerized Data Acquisition and Analysis for the Life Sciences
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£52.24
Cambridge University Press Skeletal Function and Form
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£73.14
Cambridge University Press Introduction to the Science of Medical Imaging
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£116.85
Cambridge University Press Electromechanics and MEMS
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£66.49
Cambridge University Press Bioinformatics and Computational Biology in Drug Discovery and Development
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£55.09
Cambridge University Press Biosimulation
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£94.99
Cambridge University Press Skeletal Function and Form Mechanobiology of Skeletal Development Aging and Regeneration
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£81.69
Cambridge University Press SulphateReducing Bacteria
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£147.25
Cambridge University Press ElectrokineticallyDriven Microfluidics and Nanofluidics
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£108.30
Cambridge University Press Physics of Charged Macromolecules
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£66.49
Cambridge University Press Quantitative Biomedical Optics
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£64.59
Cambridge University Press Biomedical Engineering for Global Health Cambridge Texts in Biomedical Engineering
Book SynopsisCan technology and innovation transform world health? Connecting undergraduate students with global problems, Rebecca Richards-Kortum examines the interplay between biomedical technology design and the medical, regulatory, economic, social and ethical issues surrounding global health. Driven by case studies, including cancer screening, imaging technologies, implantable devices and vaccines, students learn how the complexities and variation across the globe affect the design of devices and therapies. A wealth of learning features, including classroom activities, project assignments, homework problems and weblinks within the book and online, provide a full teaching package. For visionary general science and biomedical engineering courses, this book will inspire students to engage in solving global issues that face us all.Trade Review'As part of the Clinton Global Initiative, Rice University is launching a major initiative in global health technologies to narrow the unconscionable gap in life expectancy between rich and poor. This beautifully written volume by Rebecca Richards-Kortum will inspire and empower the next generation of engineers to make global health their calling. As President Clinton has said, 'today's generation of young people holds more power than any generation before them to make a positive impact on the world.' The next Jonas Salk or Maurice Hilleman will definitely have this book close at hand.' Thomas Kalil, University of California, Berkeley and Clinton Global Initiative'Professor Richards-Kortum has been in the forefront of giving bioengineers a conscience. This book is an excellent first step in educating engineers as to medical problems in the developing worlds and ways in which bioengineers can make a difference.' Paul Yager, Department of Bioengineering, University of Washington, Seattle'Professor Rebecca Richards-Kortum, a world leader of biomedical engineering research, an HHM investigator and NAE member, brings a global message to all scientists, indeed to all citizens of the world. Regardless of our educational background, we should be concerned about world health. Providing better treatment in a positive social environment, caring about the epidemic level of certain diseases and giving cost effective solutions to health management is not just scientifically exciting. It is also our responsibility as citizens of this world! Richards-Kortum makes it crystal-clear that engineers and scientists can provide intelligent solutions to medical problems and can improve the quality of life of our patients, our citizens, no matter where they live. The examples from Botswana or Lesotho are telling of the crisis bioengineers are facing in a global environment … I have shown my prepublication copy of Richards-Kortum's book to high school students and young undergraduates … They left my office inspired, as true, new apostles for better health treatment methods. No other book has made such transformation of young scientists in such a short time … This book will become the most influential biomedical text of our generation.' Nicholas Peppas, Fletcher S. Pratt Chair in Engineering, The University of Texas at Austin'Rebecca Richards-Kortum is one of the brightest and clearest-thinking biomedical engineers of her generation. Several years ago, she turned her attention to the uses of biomedical technology for improving world health. In her teaching, first at the University of Texas and then at Rice University, she was able to refine her observations into a vision for biomedical engineering that moves beyond the world we see each day. Now she has produced a book that will enable all of us to make the leap she made, and to see our power and obligations a bit more clearly. This is the kind of engineering book that comes around only once in a generation.' Mark Saltzman, Yale University'Helping students understand, early in their academic training, what it takes to bring novel, safe, and effective medical technologies to the patient is laudatory. Rebecca Richards-Kortum very nobly succeeds in doing that in the context of resource-challenged environments by writing a very engaging and provocative book. Bravo!' John H. Linehan, Professor of Biomedical Engineering and Medicine, Northwestern University'Biomedical engineers not only need expertise in the science, engineering and mathematics that underlies their field, they must also know the context in which biomedical engineering is practiced. Professor Richards-Kortum skilfully presents the key medical, policy, social and ethical issues that need to be considered in applying biomedical engineering. This is a comprehensive book that addresses biomedical engineering from a truly global perspective and shows students how these important issues affect the design of devices and therapies. This book will also be an important reference for all biomedical engineers.' George Truskey, Biomedical Engineering, Duke University'This outstanding book by Professor Rebecca Richards-Kortum on bioengineering and world health is based on her years of pioneering work and superb teaching on this topic at the University of Texas and Rice University. This pace-setting book focuses on the application of engineering methods and technological advances to medical technologies, with an emphasis on improving human health in the world. With the increasing globalization of science, technology and healthcare, the publication of this book is extremely timely to meet the urgent demand today. This book addresses the important questions of how to use science and technology to solve healthcare problems and how to translate these new healthcare technologies to the bedside. It also considers the important economical, legal and ethical issues associated with developing new medical technologies to improve world health. This is a very valuable book not only for teaching in fields such as bioengineering, but also for reading by the general public. It will have major positive impacts on bioengineering and world health for years to come.' Shu Chien, President of the Biomedical Engineering Society, Chair of the Department of Biomedical Engineering, University of California, San DiegoTable of ContentsPreface; 1. Emerging medical technologies: high stakes science and the need for technology assessment; 2. Bioengineering and technology assessment; 3. Health and economic data: a global comparison; 4. World health and global health challenges; 5. Healthcare systems: a global comparison; 6. Healthcare costs vs time: trends and drivers; 7. The evolution of technology: scientific method, engineering design, and translational research; 8. Prevention of infectious disease; 9. Ethics of clinical research; 10. Technologies for early detection and prevention of cancer; 11. Cost-effectiveness of screening for disease; 12. Technologies for treatment of heart disease; 13. Clinical trial design and sample size calculation; 14. Technology diffusion; 15. Regulation of health care technologies; 16. Future of bioengineering and world health; Index.
£94.99
Cambridge University Press Sensorimotor Control of Grasping Physiology and Pathophysiology
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£125.40
Cambridge University Press Regenerative Pharmacology
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£81.89
Cambridge University Press Biological Materials Science Biological Materials Bioinspired Materials and Biomaterials
Book SynopsisTaking a unique materials science approach, this text introduces students to the basic concepts and applications of materials and biomedical engineering and prepares them for the challenges of the new interdisciplinary field of biomaterials science. Split into three sections - Basic Biology Principles, Biological Materials, and Bioinspired Materials and Biomimetics - it presents biological materials along with the structural and functional classification of biopolymers, bioelastomers, foams, and ceramic composites. More traditional biomimetic designs such as Velcro are then discussed in conjunction with new developments that mimic the structure of biological materials at the molecular level, mixing nanoscale with biomolecular designs. Bioinspired design of materials and structures is also covered. Focused presentations of biomaterials are presented throughout the text in succinct boxes, emphasising biomedical applications, whilst the basic principles of biology are explained, so no priTrade Review'The union of the physical and biological sciences is in many respects one of the most exciting yet challenging aspects of scientific endeavor today. Nowhere is this more in evidence than in the area of biological materials science and engineering where many materials scientists struggle with the complex puzzle of biological form and function while biologists in turn have to deal with the invariably highly quantitative nature of the physical sciences and engineering. With this book, Meyers and Chen have delivered a true tour de force which takes the reader in clear and precise text from cells to virus-produced Li-ion batteries. This book is a must read for undergraduates, graduates and researchers alike in the rapidly expanding fields of biological, bioinspired and biomaterials science.' Robert Ritchie, Lawrence Berkeley National LaboratoryTable of Contents1. Evolution of materials science and engineering: from natural to bioinspired materials; Part I. Basic Biology Principles: 2. Self assembly, hierarchy, and evolution; 3. Basic building blocks; 4. Cells; 5. Biomineralization; Part II. Biological Materials: 6. Silicate and calcium carbonate-based composites; 7. Calcium phosphate-based composites; 8. Biological polymers and polymer composites; 9. Biological elastomers; 10. Biological foams (porous solids); 11. Functional biological materials; Part III. Bioinspired Materials and Biomimetics: 12. Bioinspired materials; 13. Molecular-based biomimetics.
£94.99
Elsevier Science Publishing Co Inc Circuits Signals and Systems for Bioengineers
Book SynopsisTable of ContentsPart I - SIGNALS 1. The Big Picture: Bioengineering Signals and Systems 2. Signal Analysis in the Time Domain 3. Signal Analysis in the Frequency Domain: The Fourier Series and the Fourier Transformation 4. Signal Analysis in the Frequency Domain - Implications and Applications Part II - SYSTEMS 5. Linear Systems Analysis in the Time Domain - Convolution 6. Linear Systems Analysis in the Frequency Domain: The Transfer Function 7. Linear Systems in the Complex Frequency Domain: The Laplace Transform 8. Analysis of Discrete Linear Systems - The z-Transform and Applications to Filters 9. System Simulation and Simulink 10. Stochastic, Nonstationary, and Nonlinear Systems and Signals 11. Two-Dimensional Signals - Basic Image Analysis PART III - CIRCUITS 12. Circuits Elements and Circuit Variables 13. Analysis of Analog Circuits and Models 14. Circuit Reduction - Simplifications 15. Basic Analog Electronics - Operational Amplifiers APPENDICES Appendix A - Derivations; Appendix B - Laplace Transforms and Properties of the Fourier; Appendix C - Trigonometric and Other Formulae; Appendix D - Conversion Factors: Units; Appendix E - Complex Arithmetic; Appendix F - LF356 Specifications; Appendix G - Determinants and Cramer's Rule
£999.99
John Wiley & Sons Inc Polyphosphazenes for Biomedical Applications
Book SynopsisThe book serves as both an introduction and a practical guide on the synthesis and use of polyphosphazenes, a new and very versatile polymer family which has recently demonstrated bioactivity, biocompatibility, and biodegradability.Table of ContentsCONTRIBUTORS. PREFACE. I INTRODUCTION. 1 Polymers for Biology and Medicine - Current Status and Future Prospects (Alexander K. Andrianov and Robert Langer). 2 Expanding Options in Polyphosphazene Biomedical Research (Harry R. Allcock). II VACCINE DELIVERY AND IMMUNOMODULATION. 3 Polyphosphazenes as Vaccine Delivery Systems (Alexander K. Andrianov). 4 The Potential of Polyphosphazenes in Modulating Vaccine-Induced Immune Responses I: Investigations In Mice (George Mutwiri, Ponn Benjamin, Alexander K. Andrianov, and Lorne Babiuk). 5 The Potential of Polyphosphazenes in Modulating Vaccine-Induced Immune Responses II: Investigations In Large Animals (George Mutwiri and Lorne Babiuk). 6 Polyphosphazenes as Adjuvants for Inactivated and Subunit Rotavirus Vaccines in Adult and Infant Mice (Kari Johansen, Jorma Hinkula, Claudia Istrate, Elin Johansson, Didier Poncet, and Lennart Svensson). 7 Polyphosphazene Immunoadjuvants for Intradermal Vaccine Delivery (Alexander K. Andrianov, Daniel P. DeCollibus, Helice A. Gillis, Henry H. Kha, Alexander Marin). III BIOMATERIALS. 8 Biodegradable Polyphosphazene Scaffolds for Tissue Engineering (Syam P. Nukavarapu, Sangamesh G. Kumbar, Harry R. Allcock and Cato T. Laurencin). 9 Biodegradable Polyphosphazene Blends for Biomedical Applications (Meng Deng, Lakshmi S. Nair, Nicholas R. Krogman, Harry R. Allcock, Cato T. Laurencin). 10 Polyphosphazenes from Condensation Polymerization (Patty Wisian-Neilson). 11 Electrospun Polyphosphazene Nanofibers For In Vitro Osteoblast Culture (Maria Teresa Conconi, Paolo Carampin, Silvano Lora, Claudio Grandi, Pier Paolo Parnigotto). 12 Phosphazenes and Surfaces (Mario Gleria, Roberto Milani, Roberta Bertani, Angelo Boscolo Boscoletto, and Roger De Jaeger). IV DRUG DELIVERY SYSTEMS. 13 Amphiphilic Ionizable Polyphosphazenes for the Preparation of pH-Responsive Liposomes (David Ghattas and Jean-Christophe Leroux). 14 Poly- and Cyclophosphazenes as Drug Carriers for Anticancer Therapy (Youn Soo Sohn and Yong Joo Jun). 15 Amphiphilic Polyphosphazenes as Drug Carriers (Liyan Qiu and Cheng Zheng). 16 Synthesis and Characterization of Organometallic Derivatives of Polyphosphazenes and their Applications in Nanoscience (Carlos Diaz and M. L. Valenzuela). 17 Transport Properties of Polyphosphazenes (Joel R. Fried). V BIODETECTION. 18 Potentiometric Monitoring Antibody-Antigen Interactions by and Stabilization of Polyanilineand Electrodes with p-Sulfonated Poly(bisphenoxyphosphazene) (Byeongyeol Kim, Alexander K. Andrianov, Alok Prabhu, Vladimir Sergeyev, and Kalle Levon). VI WELL-DEFINED POLYPHOSPHAZENES: SYNTHETIC ASPECTS AND NOVEL MOLECULAR ARCHITECTURES. 19 Synthesis and chemical regularity in phosphazene copolymers (Gabino A. Carriedo). 20 Supramolecular Structures of Cyclophosphazenes(Alexander Steiner APPENDIX A. INDEX.
£143.40
John Wiley & Sons Inc Basics of Biomedical Ultrasound for Engineers
Book SynopsisBasics of Biomedical Ultrasound for Engineers is a structured textbook for university engineering courses in biomedical ultrasound and for researchers in the field. This book offers a tool for building a solid understanding of biomedical ultrasound, and leads the novice through the field in a step-by-step manner.Table of ContentsPreface. Acknowledgments. Introduction. Prelude and Basic Definitions. The Advantages of Using Ultrasound in Medicine. A General Statement on Safety. Some Common Applications of Ultrasound. What Is It that We Need to Know? References. 1 Waves—A General Description. 1.1 General Definitions of Waves—A Qualitative Description. 1.2 General Properties of Waves—A Qualitative Description. 1.3 Mechanical One-Dimensional Waves. 1.4 The Wave Function. 1.5 The Wave Equation. 1.6 Harmonic Waves. 1.7 Group Waves. 1.8 Wave Velocity. 1.9 Standing Waves (a Mathematical Description). 1.10 Spherical Waves. 1.11 Cylindrical Waves. 1.12 The Wave Equation in a Nonhomogeneous Medium. References. 2 Waves In A One-Dimensional Medium. 2.1 The Propagation Speed of Transverse Waves in a String. 2.2 Vibration Frequencies for a Bounded String. 2.3 Wave Reflection (Echo) in a One-Dimensional Medium. 2.4 Special Cases. 2.5 Wave Energy in Strings. 2.6 Propagation of Longitudinal Waves in an Isotropic Rod or String. 2.7 A Clinical Application of Longitudinal Waves in a String. References. 3 Ultraspmoc Waves in Fluids. 3.1 Waves in Fluids. 3.2 Compressibility. 3.3. Longitudinal Waves in Fluids. 3.4 The Wave Energy. 3.5 Intensity. 3.6 Radiation Pressure. 3.7 A Perfect Reflector. References. 4 Propogation of Acoustic Waves in Solid Materials. 4.1 Introduction to the Mechanics of Solids. 4.2 The Elastic Strain. 4.3 Stress. 4.4 Hooke’s Law and Elastic Coefficients. 4.5 The Wave Equation for an Elastic Solid Material. 4.6 Propagation of a Harmonic Planar Wave in a Solid Material. References. 5 Attenuation and Dispersion. 5.1 The Attenuation Phenomenon. 5.2 Explaining Attenuation with a Simple Model. 5.3 Attenuation Dependency on Frequency. 5.4 The Complex Wave Number. 5.5 Speed of Sound Dispersion. 5.6 The Nonlinear Parameter B/A. References. 6 Reflection and Transmission. 6.1 The Acoustic Impedance. 6.2 Snell’s Law. 6.3 Reflection and Transmission from Boundaries Separating Two Fluids (or Solids with No Shear Waves). 6.4 Reflection from a Free Surface in Solids (Mode Conversion). 6.5 Reflection and Transmission from a Liquid– Solid Boundary. References. 7 ACOUSTIC LENSES AND MIRRORS. 7.1 Optics. 7.2 Optics and Acoustics. 7.3 An Ellipsoidal Lens. 7.4 Spherical Lenses. 7.5 Zone Lenses. 7.6 Acoustic Mirrors (Focusing Reflectors). References. 8 Transducers and Acoustic Fields. 8.1 Piezoelectric Transducers. 8.2 The Acoustic Field. 8.3 The Field of a Point Source. 8.4 The Field of a Disc Source. 8.5 The Field of Various Transducers. 8.6 Phased-Array Transducers. 8.7 Annular Phased Arrays. References. 9 Ultrasonic Imaging Using the Pulse-Echo Technique. 9.1 Basic Definitions in Imaging. 9.2 The “A-Line”. 9.3 Scatter Model for Soft Tissues. 9.4 Time Gain Compensation. 9.5 Basic Pulse-Echo Imaging (B-Scan). 9.6 Advanced Methods for Pulse-Echo Imaging. References. 10 Special Imaging Techniques. 10.1 Acoustic Impedance Imaging—Impediography. 10.2 Elastography. 10.3 Tissue Speckle Tracking. 10.4 Through-Transmission Imaging. 10.5 Vibro-acoustic Imaging. 10.6 Time Reversal. 10.7 Ultrasonic Computed Tomography. 10.8 Contrast Materials. 10.9 Coded Excitations. References. 11 Doppler Imaging Techniques. 11.1 The Doppler Effect. 11.2 Velocity Estimation. 11.3 Frequency Shift Estimation. 11.4 Duplex Imaging (Combined B-Scan and Color Flow Mapping). References. 12 Safety and Therapuetic Applications. 12.1 Effects Induced by Ultrasound and Safety. 12.2 Ultrasonic Physiotherapy. 12.3 Lithotripsy. 12.4 Hyperthermia HIFU and Ablation. 12.5 Drug Delivery. 12.6 Gene Therapy. 12.7 Cosmetic Applications. References. Appenidx A: Typical Acoustic Properties of Tissues. Appendix B: Exemplary Problems. Appendix C: Answers to Exemplary Problems. Index.
£110.15
John Wiley & Sons Inc Dendrimers
Book SynopsisThis book will be mainly focussed on the properties and uses of dendrimers and dendrons. The aim of this book is to be the reference book about dendrimers applications. It will not describe all details, but it will give the reader a unique overview of what has currently been done with dendrimers, with numerous references and illustrations. It will be divided in four main parts: Part 1) Generalities, syntheses, characterizations and properties; Part 2) Applications in catalysis; Part 3) Applications for the elaboration or modification of materials; and Part 4) Applications in biology/medicine. The role of the nanometric size and the multiple functions of dendrimers on the properties will be emphasized.Trade Review “The book is of high quality and recommended reading for anyone working with dendrimers or wanting to have a good reference book; rich in information, clearly organized and thoroughly referenced with topical primary publications.” (Angewandte Chemie, 2012) Table of ContentsPreface xv Part 1 Generalities, Syntheses, Characterizations, and Physicochemical Properties 1 1 Syntheses of Dendrimers and Dendrons 3 Anne-Marie Caminade 1.1 Introduction: What Are Dendrimers and Dendrons? 3 1.2 Syntheses of Poly(propyleneimine) Dendrimers (PPI) 5 1.3 Synthesis of Poly(amidoamine) Dendrimers (PAMAM) 5 1.4 Syntheses of Poly(ether) Dendrimers 7 1.5 Syntheses of Poly(ester) Dendrimers 10 1.6 Synthesis of Poly(lysine) Dendrimers 14 1.7 Syntheses of Silicon-Containing Dendrimers 15 1.8 Syntheses of Phosphorus-Containing Dendrimers 16 1.9 Syntheses of Carbon-Based Dendrimers 17 1.10 Syntheses of Dendrimers Constituted of Nitrogen Heterocycles 19 1.11 Syntheses by Self-Assembly 21 1.12 Accelerated Syntheses 26 1.13 Conclusion 30 References 30 2 Methods of Characterization of Dendrimers 35 Anne-Marie Caminade 2.1 Introduction 35 2.2 Spectroscopy and Spectrometry 36 2.2.1 Nuclear Magnetic Resonance (NMR) 36 2.2.2 Mass Spectrometry 40 2.2.3 X-ray Diffraction 41 2.2.4 Infrared (IR) and Raman Spectroscopy 42 2.2.5 Ultraviolet–Visible (UV–vis) Spectroscopy 43 2.2.6 Fluorescence 44 2.2.7 Chirality, Optical Rotation, and Circular Dichroism (CD) 45 2.2.8 Electron Paramagnetic Resonance (EPR) 45 2.2.9 Electrochemistry 46 2.2.10 Magnetometry 46 2.2.11 Mössbauer Spectroscopy 46 2.2.12 X-ray Spectroscopies 47 2.3 Scattering Techniques 47 2.3.1 Laser Light Scattering (LLS) 47 2.3.2 Small-Angle Neutron Scattering (SANS) 47 2.3.3 Small-Angle X-ray Scattering (SAXS) and Wide-Angle X-ray Scattering (WAXS) 48 2.4 Microscopy 48 2.4.1 Transmission Electron Microscopy (TEM) 49 2.4.2 Atomic Force Microscopy (AFM) 49 2.4.3 Polarizing Optical Microscopy (POM) 50 2.5 Rheology and Physical Characterizations 50 2.5.1 Intrinsic Viscosity 50 2.5.2 Differential Scanning Calorimetry (DSC) 50 2.5.3 Dielectric Spectroscopy (DS) 51 2.5.4 Dipole Moments 51 2.6 Separation Techniques 52 2.6.1 Size Exclusion Chromatography 52 2.6.2 Electrophoresis 53 2.7 Conclusion 53 References 54 3 Luminescent Dendrimers 67 Anne-Marie Caminade 3.1 Introduction 67 3.2 Dendrimers with Fluorescent Terminal Groups 68 3.2.1 Fully Substituted Dendrimers 68 3.2.2 Partially Substituted Dendrimers 69 3.3 Luminescent Group at the Core of Dendrimers and Energy/Light-Harvesting Properties 74 3.3.1 Organic Fluorophores as Cores 74 3.3.2 Porphyrins and Phthalocyanines as Cores 77 3.3.3 Metallic Cores 78 3.4 Fluorescent Groups inside the Structure of Dendrimers 79 3.5 Intrinsically Fluorescent Dendrimers 81 3.5.1 Fluorescent Groups throughout the Dendrimeric Structure 81 3.5.2 Fluorescence of Dendrimers without Known Fluorophores 86 3.6 Two-Photon-Excited Fluorescence of Dendrimers 86 3.7 Conclusion 89 References 90 4 Stimuli-Responsive Dendrimers 99 Anne-Marie Caminade 4.1 Introduction 99 4.2 Photoresponsive Dendrimeric Structures 100 4.2.1 Azobenzene-Containing Dendrimers and Dendrons 101 4.2.2 Other Types of Photoresponsive Dendrimers 108 4.3 Thermoresponsive Dendrimeric Structures 110 4.3.1 Thermoresponsive Properties of Dendrimers 110 4.3.2 Thermoresponsive Properties of Dendrons and Dendronized Polymers 112 4.4 Dendrimers Responsive to Solution Media Changes 114 4.4.1 pH-Responsive Dendrimers 114 4.4.2 Dendrimers Disassembly 115 4.5 Conclusion 117 References 118 5 Liquid Crystalline Dendrimers 125 Anne-Marie Caminade 5.1 Introduction 125 5.2 Mesogenic Groups as Terminal Functions of Dendrons 126 5.3 Mesogenic Groups as Terminal Functions of Dendrimers 131 5.4 Mesogenic Groups as Branches of Dendrimers 134 5.5 Conclusion 135 References 136 6 Dendrimers and Nanoparticles 141 Cédric-Olivier Turrin and Anne-Marie Caminade 6.1 Introduction 141 6.2 Dendrimers or Dendrons for Coating Nanoparticles 142 6.2.1 Dendronization of Nanoparticles by Ligand Exchange 142 6.2.2 Direct Synthesis of Dendronized Nanoparticles 147 6.2.3 Dendrimer Coated Nanoparticles 149 6.2.4 Nanocomposites with Interdendrimer Nanoparticles 151 6.3 Dendrimers as Templates for the Synthesis of Dendrimer-Encapsulated Nanoparticles (DENs) 152 6.3.1 Catalysis with Dendrimer-Encapsulated Nanoparticles 153 6.3.2 Other Uses of Dendrimer-Encapsulated Nanoparticles 154 6.4 Conclusion and Perspectives 154 References 155 Part 2 Applications in Catalysis 163 7 Terminal Groups of Dendrimers as Catalysts for Homogeneous Catalysis 165 Armelle Ouali and Anne-Marie Caminade 7.1 General Introduction 165 7.1.1 The “Dendrimer Effect” 165 7.1.2 Recycling the Catalysts 166 7.2 Catalytic Organometallic Sites as Catalysts for Homogeneous Catalysis 167 7.2.1 Formation of C–X Bonds (X = C, N, O) 167 7.2.2 Addition Reactions on a C=X Double Bond (X = C, O) 175 7.2.3 Oxidation Reactions 177 7.3 Organocatalysis with Dendrimers 178 7.4 Conclusion 178 References 179 8 Catalytic Sites inside the Dendrimeric Structure for Homogeneous Catalysis 183 Armelle Ouali and Anne-Marie Caminade 8.1 Introduction 183 8.2 Catalytic Sites as the Core of Dendrimers 184 8.2.1 Dendrimers Bearing a Transition-Metal-Based Complex at the Core 184 8.2.2 Dendrimers Bearing an Organocatalyst at the Core 188 8.3 Catalytic Sites inside the Branches of Dendrimers 191 8.3.1 Formation of C–X Bonds (X = C, N, O) 191 8.3.2 Addition Reactions on a C=C Double Bond: Olefi n Hydrogenation 192 8.4 Conclusion 192 References 193 9 Dendrimers as Homogeneous Enantioselective Catalysts 197 Armelle Ouali and Anne-Marie Caminade 9.1 Introduction 197 9.2 Catalytic Organometallic Sites as Catalysts for Homogeneous Catalysis 198 9.2.1 Formation of C–X Bonds (X = C, N, O) 198 9.2.2 Addition Reactions on a C=X Double Bond (X = C, O) 204 9.3 Organocatalysis with Dendrimers 209 9.3.1 Aldolizations 209 9.3.2 Aza–Morita–Baylis–Hillmann Reactions 209 9.3.3 Transaminations 210 9.4 Conclusion 210 References 210 10 Catalysis with Dendrimers in Particular Media 215 Régis Laurent and Anne-Marie Caminade 10.1 Introduction 215 10.2 Two-Phase (Liquid–Liquid) Media 216 10.3 Catalysis in Ionic Liquids 219 10.4 Catalysis in Supercritical Media 220 10.5 Catalysis in Aqueous Media 221 10.6 Conclusion 234 References 234 11 Heterogeneous Catalysis with Dendrimers 239 Régis Laurent and Anne-Marie Caminade 11.1 Introduction 239 11.2 Catalysis with Dendrons Synthesized from a Solid Material 240 11.2.1 Silica as an Inorganic Support 240 11.2.2 Polymers and Resins as Organic Supports 248 11.3 Catalysis with Dendrons or Dendrimers Grafted on to a Solid Surface 254 11.4 Catalysis with Insoluble Dendrimers 257 11.5 Conclusion 260 References 261 Part 3 Applications for the Elaboration or Modification of Materials 267 12 Dendrimers inside Materials 269 Régis Laurent and Anne-Marie Caminade 12.1 Introduction 269 12.2 Dendrimers for the Elaboration of Gels 270 12.2.1 Dendrimers for the Elaboration of Supramolecular Hygrogels 270 12.2.2 Dendrimers for the Elaboration of Polymer-Type Hygrogels 273 12.2.3 Dendrimers for the Elaboration of Organogels 276 12.3 Dendrimers inside Silica Gels 280 12.4 Dendrimers inside Other Types of Materials 285 12.5 Dendrimers for the Elaboration of OLEDs 288 12.5.1 Fluorescent Dendrimers for the Elaboration of OLEDs 290 12.5.2 Phosphorescent Dendrimers for the Elaboration of OLEDs 295 12.6 Conclusion 298 References 299 13 Self-Assembly of Dendrimers in Layers 313 Béatrice Delavaux-Nicot and Anne-Marie Caminade 13.1 Introduction 313 13.2 Langmuir–Blodgett Films of Dendrons and Dendrimers 314 13.2.1 Poly(benzyl ether) Derivatives 316 13.2.2. Poly(amidoamine) and Poly(propyleneimine) Derivatives 319 13.2.3 Azobenzene Derivatives 320 13.2.4 Poly(carbosilane) Dendrimer Derivatives 321 13.2.5 Fullerene C60 Derivatives 322 13.2.6 Other Examples 325 13.3 Assemblies of Dendrons and Dendrimers on Solid Surfaces 326 13.3.1 Assembly of Dendrons and Dendrimers on Gold Surfaces 327 13.3.2 Assembly of Dendrons and Dendrimers on Silicon Substrates or Related Substrates 330 13.4 Several Routes for the Formation of Dendron or Dendrimer Multilayers 334 13.5 Nanoimprinting with Dendrons and Dendrimers on Solid Surfaces 342 13.5.1 Dendrimer-Based Self-Assembled Monolayers as Resists for Scanning Probe Lithography 342 13.5.2 Microprinting, Transfer Printing, and Dip-Pen Nanolithography with Dendrimers 344 13.6 Conclusion 350 References 351 14 Dendrimers as Chemical Sensors 361 Anne-Marie Caminade 14.1 Introduction 361 14.2 Dendrimers as Chemical Sensors in Solution 362 14.2.1 Porphyrins and Other Macrocyclic Derivatives as the Core or Branches of Dendrimeric Sensors 362 14.2.2 Terminal Groups of Dendrimers as Sensors in Solution 363 14.3 Dendrimers as Electrochemical Sensors 365 14.4 Dendrimers on Modifi ed Surfaces as Chemical Sensors 367 14.4.1 Dendrimers on Surfaces at the Interface with a Solution 367 14.4.2 Dendrimers on Surfaces at the Interface with a Vapor 368 14.5 Conclusion 370 References 370 15 Dendrimers as Biological Sensors 375 Anne-Marie Caminade 15.1 Introduction 375 15.2 Dendrimers as Sensors in Solutions of Biological Media 375 15.3 Detection by Electrochemical Methods 378 15.4 Dendrimers or Dendrons for DNA Microarrays 380 15.5 Dendrimers for Other Types of Biomicroarrays 383 15.6 Dendrimers on Other Types of Support 384 15.7 Dendrimers as Multiply Labeled Entities Connected to the Target 385 15.8 Conclusion 386 References 387 Part 4 Applications in Biology/Medicine 393 16 Dendrimers for Imaging 395 Cédric-Olivier Turrin and Anne-Marie Caminade 16.1 Introduction 395 16.2 Magnetic Resonance Imaging with Dendrimers 395 16.2.1 Paramagnetic Dendrimer-Based Contrast Agents 398 16.2.2 PARACEST Dendrimer-Based Contrast Agents 402 16.2.3 Superparamagnetic Dendrimer-Based Contrast Agents 402 16.2.4 Dendrimer-Based 129Xe HYPER-CEST MRI Contrast Agents 403 16.2.5 19F Dendrimer-Based MRI Contrast Agents 403 16.3 Other Types of Imaging with Dendrimers 403 16.3.1 Dendrimers for Optical Imaging 403 16.3.2 Dendrimers for Nuclear Medicine (NM) Imaging and Computed Tomography X-Ray Imaging (CT) 405 16.4 Conclusion and Perspectives 407 References 407 17 Dendrimers as Transfection Agents 413 Cédric-Olivier Turrin and Anne-Marie Caminade 17.1 Introduction 413 17.2 Gene Transfection with PAMAM Dendrimers 415 17.2.1 Pioneering Results 415 17.2.2 Gene Transfection with Surface-Modifi ed PAMAM 416 17.2.3 Gene Transfection with Core-Modifi ed PAMAM 418 17.2.4 Gene Transfection with PAMAM-Functionalized Nanoparticles 419 17.2.5 Gene Transfection with PAMAM-Like Hyperbranched Polymers 420 17.3 Gene Transfection with Other Dendrimers 421 17.3.1 Gene Transfection with PPI Dendrimers 421 17.3.2 Gene Transfection with Peptide-Based Dendrimers 422 17.3.3 Gene Transfection with Phosphorus-Based Dendrimers 423 17.3.4 Gene Transfection with Silane-Based Dendrimers 424 17.4 Conclusion and Perspective 426 References 426 18 Dendrimer Conjugates for Drug Delivery 437 Cédric-Olivier Turrin and Anne-Marie Caminade 18.1 Introduction 437 18.2 Improving Bioavailability with Dendrimers 438 18.3 Passive Targeting in Tumors with Dendrimer–Drug Conjugates 440 18.3.1 Dendrimer–Drug Bioconjugates and the EPR Effect 440 18.3.2 PEGylated Dendrimeric Scaffolds 442 18.4 Active Targeting with Site-Specifi c Dendrimer–Drug Conjugates 446 18.4.1 Addressing with Folic Acid (FA) 446 18.4.2 Addressing with Tumor-Homing Peptides 448 18.4.3 Addressing with Monoclonal Antibodies 449 18.5 Dendrimers for Photodynamic Therapy (PDT) 449 18.6 Dendrimers for Boron Neutron Capture Therapy (BNCT) 451 18.7 Conclusion and Perspectives 452 References 453 19 Encapsulation of Drugs inside Dendrimers 463 Cédric-Olivier Turrin and Anne-Marie Caminade 19.1 Introduction 463 19.2 From Dendritic Boxes to Dendrimer-Based Formulations 464 19.3 Improving Bioavailability with Dendrimers? 464 19.4 Toxicological Issues 465 19.5 Dendrimer-Based Formulations for Drug Delivery 466 19.5.1 Nontargeted Formulations 466 19.5.2 Supramolecular Assemblies Involving Surface Ionic Interactions 473 19.5.3 Targeted Formulations 475 19.6 Conclusion and Perspectives 477 References 477 20 Unexpected Biological Applications of Dendrimers and Specifi c Multivalency Activities 485 Cédric-Olivier Turrin and Anne-Marie Caminade 20.1 Introduction 485 20.2 Dendrimers and Multivalency 486 20.2.1 Multivalent Effects and Dendrimeric Effects 486 20.2.2 Glycodendrimers 487 20.3 Antimicrobial Dendrimers 488 20.3.1 Polycationic Dendrimers 489 20.3.2 Polyanionic Dendrimers 491 20.4 From Immunomodulation to Regenerative Medicine 494 20.4.1 Immunomodulation and Anti-Inflammation 494 20.4.2 Dendrimers and Regenerative Medicine 498 20.5 Conclusion and Perspectives 501 References 502 21 General Conclusions and Perspectives 511 Anne-Marie Caminade Index 515
£999.99
John Wiley & Sons Inc Differential Equation Analysis in Biomedical
Book SynopsisFeatures a solid foundation of mathematical and computational tools to formulate and solve real-world ODE problems across various fields With a step-by-step approach to solving ordinary differential equations (ODEs), Differential Equation Analysis in Biomedical Science and Engineering: Ordinary Differential Equation Applications with R successfully applies computational techniques for solving real-world ODE problems that are found in a variety of fields, including chemistry, physics, biology, and physiology. The book provides readers with the necessary knowledge to reproduce and extend the computed numerical solutions and is a valuable resource for dealing with a broad class of linear and nonlinear ordinary differential equations. The author's primary focus is on models expressed as systems of ODEs, which generally result by neglecting spatial effects so that the ODE dependent variables are uniform in space. Therefore, time is the independent variable in Table of ContentsPreface ix 1. Introduction to Ordinary Differential Equation Analysis: Bioreactor Dynamics 1 2. Diabetes Glucose Tolerance Test 79 3. Apoptosis 145 4. Dynamic Neuron Model 191 5. Stem Cell Differentiation 217 6. Acetylcholine Neurocycle 241 7. Tuberculosis with Differential Infectivity 321 8. Corneal Curvature 337 Appendix A1: Stiff ODE Integration 375 Index 417
£97.80
ISTE Ltd and John Wiley & Sons Inc Photon-based Medical Imagery
Book SynopsisThis book describes the different principles and equipments used in medical imaging. Importance of medical imaging for diagnostic is strongly increasing and it is now necessary to have a good knowledge of the different physical possible principles. Researchers, clinicians, engineers and professionals in this area, along with postgraduate students in the signal and image processing field, will find this book of great interest.Table of ContentsForeword xi Guy FRIJA Chapter 1. Interactions between Radiation and Matter: Consequences for Detection and Medical Imaging 1 Jean-Pierre MOY 1.1. The limits of imaging using light 1 1.2. Imaging with other types of radiation 2 1.3. X-rays: their interaction with matter 3 1.4. Radiological imaging relies on the X-ray-matter interaction 19 1.5. Consequences of interaction modes on detection 22 1.6. Conclusion 33 1.7. Bibliography 33 Chapter 2. Detectors for Medical Imaging 35 Hervé FANET 2.1. Radiation-matter interaction and signal formation 36 2.2. Flux, energy, time and position measurements 64 2.3. Semi-conductor detectors 86 2.4. Scintillation and measurement channel 102 2.5. Pixel detectors 116 2.6. Bibliography 121 Chapter 3. Quantitative Digital Radiography Image Processing 123 Jean RINKEL and Jean-Marc DINTEN 3.1. Introduction to flat-panel sensors 123 3.2. Relation between physical quantities and radiographic acquisition 129 3.3. Access to linear attenuation coefficients from the attenuation image 133 3.4. Access to physical dimensions by combining several X-rays of a flat sensor 149 3.5. Conclusion 158 3.6. Bibliography 159 Chapter 4. X-Ray Tomography 161 Françoise PEYRIN and Philippe DOUEK 4.1. Introduction 161 4.2. Principle of the first acquisition systems 162 4.3. Physical aspects and the direct problem 165 4.4. Principle of tomographic image reconstruction 169 4.5. Evolution of X-ray scanners and reconstruction algorithms 181 4.6. Examples of clinical applications 189 4.7. From tomography to micro-tomography 198 4.8. Conclusion 200 4.9. Bibliography 201 Chapter 5. Positron-Emission Tomography: Principles and Applications 207 Régine TRÉBOSSEN 5.1. Introduction 208 5.2. PET: principle and performance 210 5.3. PET systems 218 5.4. PET for cancer staging 223 5.5. Conclusion 225 5.6. Bibliography 226 Chapter 6. Single Photon Imaging 229 Irène BUVAT 6.1. Introduction 229 6.2. Overview of single photon imaging 230 6.3. Conventional detection systems in single photon imaging: the scintillation gamma camera 233 6.4. Innovative systems: semiconductor detectors 240 6.5. Tomographic reconstruction and corrections 241 6.6. Hybrid detectors 258 6.7. Applications 259 6.8. Future developments 261 6.9. Conclusion 262 6.10. Bibliography 262 Chapter 7. Optical Imaging 267 Anabela DA SILVA 7.1. Introduction 267 7.2. Physics of luminous propagation in biological tissue 268 7.3. Different optical imaging techniques for different applications 289 7.4. Conclusion 312 7.5. Bibliography 313 List of Authors 325 Index 327
£135.80
World Health Organization Medical Devices: Managing the Mismatch: An
Book Synopsis
£52.38
