Biology, life sciences Books

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Book SynopsisThis anthology of essays presents a sample of studies from recent philosophy of medicine addressing issues which attempt to answer very general (interdependent) questions: (a) what is a disease and what is health? (b) How do we (causally) explain diseases? (c) And how do we distinguish diseases, i.e. define classes of diseases and recognize that an instance X of disease belongs to a given class B? (d) How do we assess and choose cure/ therapy?The book is divided into three sections: classification, disease and evidence. In general, attention is focused on statistics in medicine and epidemiology, issues in psychiatry and connecting medicine with evolutionary biology and genetics. Many authors position the theories that they address within their historical contexts.The nature of health and disease will be addressed in several essays that also touch upon very general questions about the definition of medicine and its status. Several chapters scrutinize classification because of its centrality within philosophical problems raised by medicine and its core position in the philosophical questioning of psychiatry. Specificities of medical explanation have recently come under a new light, particularly because of the rise of statistical methods and several chapters investigate these methods in specific contexts such as epidemiology or meta-analysis of random testing. Taken together this collection addresses the question of how we gather, use and assess evidence for various medical theories.The rich assortment of disciplines featured also includes epidemiology, parasitology and public health, while technical aspects such as the application of game theory to medical research and the misuse of the DSM in forensic psychiatry are also given an airing. The book addresses more than the construction of medical knowledge, however, adding cogent appraisal of the processes of decision making in medicine and the protocols used to justify therapeutic choices.Trade Review“This volume is a collection of philosophy of medicine chapters that deal, in one way or another, with the three linked themes of the title. … The chapters are well-researched and well-written and provide the reader with a useful snapshot of contemporary philosophy of medicine. … this book is a valuable addition to the research literature. ” (Brendan Clarke, Metascience, Vol. 25, 2016)Table of ContentsIntroduction.- Evolutionary Models of Virulence: Concepts, History and Current Applications; Alizon, Sam and Méthot, Pierre Olivier.-Objectivity, Scientificity, and the Dualist Epistemology of Medicine; Cunningham; Thomas.- The Function Debate and the Concept of Mental Disorder; Steeves, Demazeux.- Defining genetic disease; Dekeuwer; Catherine.- Causal and probabilistic inferences in diagnostic reasoning: casting a historical light onto the current debates; Coste, Joël.- Risk factor and causality in epidemiology; Giroux, Elodie.- The naturalization of the concept of disease; Lemoine, Mael.- The Epistemology of Mental Illness; Dominic Murphy.- Power, Knowledge and Laughter: Forensic Psychiatry and the misuse of the DSM; Singy, Patrick.- Quality Assessment Tools for Evidence in Medicine; Stegenga, Jacob.

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book SynopsisThis highly unusual book is a serious inquiry into Schrödinger's question, “What is life?”, and at the same time a celebration of life itself. It takes the reader on a voyage of discovery through many areas of contemporary physics, from non-equilibrium thermodynamics and quantum optics to liquid crystals and fractals, all necessary for illuminating the problem of life. In the process, the reader is treated to a rare and exquisite view of the organism, gaining novel insights, not only into the physics but also into “the poetry and meaning of being alive”. This book is intended for all who love the subject.Table of ContentsWhat is it to be alive?; do organisms contravene the second law?; can the second law cope with organized complexity; energy flow and living cycles; how to catch a falling electron; photocopy and chapter; the 73 octaves of nature's music; the coherent excitation of the body electric; how coherent is the organism?; life is all the colours of the rainbow in a worm; the liquid crystalline organism; crystal consciousness; quantum entanglement and coherence; the ignorance of the external observer; time and freewill.

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Book Synopsis'This is a book that required a great many research hours, the kind of volume you may be glad someone took the time to compile.'The Quarterly Review of Biology This is the ultimate guide to the life and work of Charles Darwin. The result of decades of research through a vast and daunting literature which is hard for beginners and experts alike to navigate, it brings together widely scattered facts including very many unknown to even the most ardent Darwin aficionados. It includes hundreds of new discoveries and corrections to the existing literature. It provides the most complete summaries of his publications, manuscripts, lifetime itinerary, finances, personal library, friends and colleagues, opponents, visitors to his home, anniversaries, hundreds of flora, fauna, monuments and places named after him and a host of other topics. Also included are the most complete lists (iconographies) ever created of illustrations of the Beagle, over 1000 portraits of Darwin, his wife and home as well as all known Darwin photographs, stamps and caricatures. The book is richly illustrated with 350 images, most previously unknown.

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Book SynopsisThis book provides the latest information of life science databases that center in the life science research and drive the development of the field. It introduces the fundamental principles, rationales and methodologies of creating and updating life science databases. The book brings together expertise and renowned researchers in the field of life science databases and brings their experience and tools at the fingertips of the researcher. The book takes bottom-up approach to explain the structure, content and the usability of life science database. Detailed explanation of the content, structure, query and data retrieval are discussed to provide practical use of life science database and to enable the reader to use database and provided tools in practice. The readers will learn the necessary knowledge about the untapped opportunities available in life science databases and how it could be used so as to advance basic research and applied research findings and transforming them to the benefit of human life.Chapter 2 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.Table of ContentsChapter 1: GENCODE Annotation for the Human and Mouse Genome: A User Perspective.- Chapter 2: Genecard a database for gene annotation.- Chapter 3: IHEC: International human epigenome portal.- Chapter 4: Atlas of miRNAs and their Promoters in Human and Mouse.- Chapter 5: RefEX- Reference Expression Dataset.- Chapter 6: The mouse Gene Expression Database.- Chapter 7: ChIP-Atlas.- Chapter 8: Protein structural changes based on structural comparison.- Chapter 9: Single Cell Databases: an Emerging and Essential Tool.- Chapter 10: scIVA: Single Cell Interactive Visualisation and Analysis Data Mining Platform.- Chapter 11: Access and visualise high quality gene expression data with Stemformatics.- Chapter 12: Introduction to Practical Guide to Life Science Databases.

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Book SynopsisThis book summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets of ADCs and their specific functions. The second part mainly introduces the endocytosis and intracellular metabolism of ADCs, including the relationship between endocytosis and ADC activity, the endocytosis and intracellular transport of ADCs, the distribution and metabolism of ADC in vivo. Then it discusses the new formats and research technology of ADCs, including the application of miniaturized antibodies in ADC synthesis, novel carriers for ADC design, the technology and application of site-specific conjugation, and approaches for analyzing the drug: antibody ratio (DAR), the study of pharmacokinetics of ADCs. This book combines the basic theory with the research technology. It can be used as a reference book for students, teachers and researchers of biomedical field.Table of ContentsAntibody-Drug Conjugates Basic Concepts and Structures.- Relationship between target and specific action of antibody-drugs conjugates.- The internalization and therapeutic activity of antibody drug conjugate.- The internalization and intracellular trafficking of ADC.- Distribution and metabolism of antibody-drug conjugates.- Application of Antibody fragments in ADCs.- Novel Targeting Carriers in Antibody-drug Conjugates.- Site-specified Conjugating Technology and Application.- Determination of drug-to-antibody ratio of ADCs.- Pharmacokinetic study of antibody-drug conjugates.

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Book SynopsisThis imaging textbook covers in detail the beginning of neuromolecular imaging from in vivo electrochemistry. It discusses how neuromolecular imaging solved the persistent problem of electrocatalysis with empirical recording with the new imaging nanotechnology and circuits designed by the author. The BRODERICK PROBE nanobiosensor is smaller than one strand of human hair, does not scar, and does not produce bacterial growth. These properties of the nanobiosensor have been validated by pathologists and immunologists from New York University clinical and preclinical departments. The book details this specialized sensor's success in clinical and research settings, the biomedical engineering involved in its manufacture, and original, tried, and trusted protocols for use by scientists and practitioners in multiple fields of brain application and sensor design.

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Book SynopsisThis book is a novel attempt at describing the fundamental aspects of and advancements in the field of biohythane production. The comprehensive collection of chapters is based on the fundamentals of heterotrophic hydrogen production and consequent methane production technologies. Emphasis is on the integration of two stages of a hybrid system for maximum gaseous energy generation from organic wastes, thus making the overall process economically viable. Readers get insight into the technological advancements made in the field of biohydrogen and biomethane production and the challenges involved in integrating these two technologies. The book also includes details of the microbiological, biochemical, and bioprocess aspects related to biohythane production, in addition to the applicability of this process, its socioeconomic concerns, and cost energy analysis, supplemented with illustrative diagrams, flowcharts, and comprehensive tables. It will be an ideal vade mecum for advanced undergraduate- and graduate-level students of biotechnology, microbiology, biochemical engineering, chemical engineering, and energy engineering; teachers and researchers in bioenergy, the environment, and biofuel production; and policy makers.Trade Review"This book is a comprehensive text on the use of biohythane for sustainable energy production, covering all the aspects of the topic, from simple but fundamental concepts to a detailed description of the scientific, technological, and economic issues of biohythane production and the most relevant theoretical aspects of the processes described. This book is very useful for both students approaching the topic for the first time and researchers already working in the field."—Prof. Roberto De Philippis, University of Florence, Italy "This timely book provides a comprehensive account of the scientific and technological advancements in biohydrogen and biomethane production processes and highlights the challenges involved in integrating the two. It also presents details of the microbiology, biochemistry, and bioprocess aspects of biohythane production. It will be an excellent reference book for faculty, students, and researchers in biochemical and energy engineering, as well as practicing engineers and policy makers concerned with biofuel production and formulation of policies for promoting biofuels. It is a must for the bookshelves of all those interested in R&D in the area of biofuels."—Dr. S. N. Upadayay (Professor Emeritus), Indian Institute of Technology (BHU), IndiaTable of ContentsBiochemistry of biohythane production process. Mathematical modeling and simulation of biohydrogen production processes. Mathematical modeling and simulation of biohydrogen production processes. Modeling and simulation of biomethanation process using organic wastes. Scale-up of biohydrogen production processes and Case studies. Two-stage biomethanation process for the stabilization of distillery effluents using immobilized whole cell system – A Case study. Feedstock for biohythane process. Effect of physico-chemical parameters on the biohythane process. Policy of biohythane technology.

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Book SynopsisThis book deals with evolving intelligence systems and their use in immune algorithm (IM), particle swarm optimization (PSO), bacterial foraging (BF), and hybrid intelligent system to improve plants, robots, etc. It discusses the motivation behind research on and background of evolving intelligence systems and illustrates IM-based approach for parameter estimation required for designing an intelligent system. It approaches optimal intelligent tuning using a hybrid genetic algorithm–particle swarm optimization (GA-PSO) and illustrates hybrid GA-PSO for intelligent tuning of vector system. Table of ContentsBackground. Immune Network–Based Parameter Estimation. Intelligent PID Controller Tuning Using a Hybrid GA-PSO Approach. GA-PSO-Based PI Controller Tuning for Indirect Vector Control of Three-Phase Induction Motor. Novel Hybrid System Based on GA and Bacteria Foraging. Conclusion.

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Book SynopsisThe embedding of any new technologies in society is challenging. The evolving state of the scientific art, often-unquantifiable risks and ill-defined developmental trajectories have the potential to hinder innovation and/or the commercial success of a technology. The are, however, a number of tools that can now be utilized by stakeholders to bridge the chasm that exists between the science and innovation dimensions on the one hand, and the societal dimensions on the other. This edited volume will draw together leading researchers from the domains of law, philosophy, political science, public administration and the natural sciences in order to demonstrate how tools such as, for example, constructive technology assessment, regulatory governance and societal scenarios, may be employed by stakeholders to assist in successfully embedding new technologies into society. This volume will focus primarily on the embedding of two emergent and emerging technologies: nanotechnologies and synthetic biology. Government, industry and the epistemic community continue to struggle with how best to balance the promised benefits of an emerging technology with concerns about its potential impacts. There is a growing body of literature that has examined these challenges from various cultural, scientific and jurisdictional dimensions. There is, however, much work that still needs to be done; this includes articulating the successes and failures of attempts to the societal embedding of technologies and their associated products. This edited volume is significant and timely, as unlike other books currently on the market, it shall draw from real work experiences and experiments designed anticipate the societal embedding of emerging technologies. This empirical work shall be supported by robust theoretical underpinnings.Table of ContentsIntroduction - Foxes become hedgehogs. Reflexive co-evolution and governance patterns. Governance approaches for emerging technologies. Society as a laboratory to experiment with new technologies. Care and technoscience: re-embedding the future of innovation. Division of moral labour as an element in the governance of emerging technologies. Ethical reflexivity as capacity building: supportive tools and approaches. The demand side of innovation governance: Demand articulation processes in the case of nano-based sensor technologies. Evolving Patterns of Governance of and by Expectations. The Graphene Hype Wave. Transnational challenges of governing new technologies: The case of nanotechnology. Co-Regulation of Nanomaterials: On Collaborative Business Association Activities directed at Contributing to Occupational Health and Safety. The ‘Metamorphosis’ of the drone: the governance challenges of drone technology in border surveillance. On the disruptive potential of 3D printing. Modifying Materials, Mosquitoes and Measures: The Regulation of Nanotechnologies and Synthetic Biology. Conclusions.

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Book Synopsis.- Chapter 1: Introduction of Metal-organic Frameworks   .- Chapter 2: Metal-organic Frameworks: Photochemical and Electrochemical Properties                                              .- Chapter 3: Metal-organic Frameworks for detection of Fingerprint latent                                          .- Chapter 4: Metal-organic Frameworks for detection of Lip-print and Palm-print                                        .- Chapter 5: Metal-organic Frameworks for detection of Pesticides in forensic samples.- Chapter 6: Metal-organic Frameworks for detection of Antibiotics in forensic samples.- Chapter 7: Metal-organic Frameworks for detection of Drugs of abuse.- Chapter 8: Metal-organic Frameworks for detection of Hazardous chemicals .- Chapter 9: Metal-organic Frameworks for detection of Explosives    .- Chapter 10:Metal-organic Frameworks for detection of Gunshot residual.- Chapter 11:Metal-organic Frameworks for detection of Toxic Gases                                                                  .- Chapter 12:Metal-organic Frameworks for detection of Toxic Liquids .- Chapter 13:Advantages and disadvantages of MOFs during Forensic sample detection.

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Book SynopsisChapter 1_Different sources of starch conventional and non convential sources of starches.- Chapter 2_Structure and morphology of different sources of starches.- Chapter 3_Digestion of starch.- Chapter 4_Glycemic index of starch.- Chapter 5_Food industries.- Chapter 6_Non-food industries.- Chapter 6_Starch aerogels as a functional ingredient, drug delivery systems, fat replacer, food packaging.- Chapter 7_3D printed starch food for nutraceutical benefits.- Chapter 8_Starch based green flexible electronics.- Chapter 9_Chemical-crosslinking, acid-hydrolysis, oxidation, esterification, etherification.- Chapter 10_Physical.- Chapter 11_Enzymatic- amylases and pullulanase.- Chapter 12_Starch modifications usin

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Book SynopsisLeah Elson draws upon her wildly popular web series, 60 Seconds of Science, for an irreverent debut that answers all sorts of scientific questions-from the age-old to the ridiculous to the sublime-posed by her fans around the world.There Are (No) Stupid Questions ... in Science was born from Leah's popular web series, 60 Seconds of Science, wherein her avid followers, from all around the world, suggest topics to be explained within sixty seconds.In the vein of Astrophysics for People in a Hurry by Neil DeGrasse Tyson and The Complete Manual of Things That Might Kill You: A Guide to Self-Diagnosis for Hypochondriacs by Jen Bilik, There Are (No) Stupid Questions ... in Science provides easy-to-understand and delightfully cheeky explanations for scientific and medical quandaries, and is appropriate for everyone from those with no prior scientific knowledge to colleagues in the scientific field.

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book Synopsis

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Book Synopsis

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