Description
Book SynopsisPaul argues that we must position ourselves to take advantage of cutting-edge technologies and promising new tools in immunological research, including big data and the microbiome.
Trade ReviewAn excellent overview of what science knows about immunology today. -- Harriet Hall Science-Based Medicine Written by a prominent researcher and scholar who not only followed the history of immunology but also participated in its creation, Immunity could be considered as an excellent summary of the classical, pre-systemic, immunological era. Metascience It is well written, informative and gives detailed descriptions even down to defining platelets- sometimes we make the assumption that individuals know these details but the author has pre-empted this and provided ample explanations, which in essence will widen his audience... I would recommend this book to students, healthcare assistants, clinicians, and nurse specialists working within all areas. In essence this book could be read by individuals who have an keen interest within immunity but is written in such a way that it is accessible to those who have little or no knowledge within this area as the book is so informative. Nursing Times
Table of ContentsPreface
Part One
1. Defense and Danger
2. Tracing an Immune Response
3. The Laws of Immunology
4. Growing Up and Learning Immunology
Part Two
5. Vaccines and Serum Therapy
6. How Is Specificity Achieved?
7. Immunology's "Eureka"
8. How Does Each Lymphocyte Develop a Distinct Receptor?
9. B Cells and T Cells Recognize Different Types of Antigens
10. My Foray into the Specificity Problem
11. Genes and Immune Responses
12. The Laboratory of Immunology and the T-Cell Receptor
Part Three
13. What Is Tolerance?
14. How Does Tolerance Develop?
15. Regulatory T Cells and the Prevention of Autoimmunity
Part Four
16. Different Structures, Different Functions
17. Specific Types of Infections, Specific Types of T-Cell Responses
18. Our Discovery of IL-4 and the Cells That Make It
19. CD8 T Cells
20. Dendritic Cells
Part Five
21. An "Ancient" Immune Response Controls" Modern" Immunity
22. The Microbiome and Innate Immunity
23. Evolution of the Immune System and Innate Lymphoid Cells
Part Six
24. The HIV Epidemic and the Office of AIDS Research
25. How the Immune System Causes Rheumatoid Arthritis and Lupus
26. Allergy and Asthma
27. Interleukin-4 and Allergy
28. Can the Immune System Control Cancer?
29. New Parts for Old
30. Julien
Conclusion
Epilogue
Acknowledgments
Notes
Index
