Description
Book SynopsisExamining the science of geriatrics and converting its concepts into clinical applications, this groundbreaking work provides clinicians and researchers with a solid foundation for a greater understanding of the diagnosis, treatment, and prevention of age-related diseases as well as recommendations for promoting healthy aging.
Trade ReviewHamerman leads the advanced and careful reader to a better understanding of the relationships between the biology of aging and the emergence of aging-related diseases. Choice 2008 A unique presentation based on the author's many decades of research and experience in the science of aging. It is extremely well documented with more than a thousand references and a helpful reference... an important source of information from an expert. -- Dr. Steven Schwartz Riverdale Press 2008 The nexus between obesity, heart disease, diabetes, cancer, and Alzheimer's disease is tantalizing. It takes the hand of a master to synthesize so much material and give a unified overarching view of the relationship between aging and disease. This skillful hand is seen in the smooth flow of the book and a most pleasurable style of writing. -- David O. Staats Doody's Review Service 2008 A must-read for clinicians providing primary care in geriatrics -- Laura J. Niedernhofer Journal of Clinical Investigation 2008 An inspiring, concise, comprehensive, and stimulating primer of the field for aspiring gerontologists, geriatricians, and other physicians who will care for elderly persons. -- William B. Hazzard, MD JAMA 2008 The depth of knowledge presented is astounding... It is a must read for young and in-training geriatricians. -- Dr. Denise Zwahlen-Minton Pharos 2009 I found much of interest in the collection. -- John E. Morley Ageing and Society 2008
Table of ContentsForeword by Robert N. Butler
Preface
1. The Emergence and Future of Geriatrics
2. An Introduction to Concepts of Molecular Biology
3. Aging
I. Trends in the Aging of the Population
II. What Is Aging? Can We Distinguish betweenAging and Disease?
III. Mechanisms of Aging
IV. Longevity: Genetics of Extended Life Span or Risk for Adverse Events
4. Interrelations of Certain Aging-related Conditions
I. Cytokines, Inflammation, and Responses to Stress
II. Atherosclerosis: Risk Factors for Cardiovascular Disease
III. The Metabolic Syndrome and Type 2 Diabetes
IV. Osteoporosis
V. Osteoarthritis
VI. Frailty and Related Conditions: Anorexia, Sarcopenia, Exercise
VII. Cancer
VIII. Alzheimer Disease
5. Interactive Therapies Significant for an Aging Population
I. Cyclooxygenases
II. Statins
III. Bisphosphonates
IV. Thiazolidinediones and Peroxisome Proliferatoractivated Receptor
V. Cytokine Inhibitors as a Landmark for Newer Anti-inflammatory Therapies
VI. Hormonal Therapies
6. Preventive Gerontology
I. The Compression or Expansion of Morbidity?
II. Healthy Lifestyle Practices
III. "Successful Aging"
Epilogue
Glossary
References
Index
