Description

Book Synopsis
Complex multivariate testing problems are frequently encountered in many scientific disciplines, such as engineering, medicine and the social sciences. As a result, modern statistics needs permutation testing for complex data with low sample size and many variables, especially in observational studies.

The Authors give a general overview on permutation tests with a focus on recent theoretical advances within univariate and multivariate complex permutation testing problems, this book brings the reader completely up to date with today's current thinking.

Key Features:

  • Examines the most up-to-date methodologies of univariate and multivariate permutation testing.
  • Includes extensive software codes in MATLAB, R and SAS, featuring worked examples, and uses real case studies from both experimental and observational studies.
  • Includes a standalone free software NPC Test Release 10 with a graphical interface which allows practitioners from every scientifi

    Table of Contents
    Contents

    Preface

    Notation and Abbreviations

    1 Introduction

    1.1 On Permutation Analysis

    1.2 The Permutation Testing Principle

    1.3 Permutation Approaches

    1.4 When and Why Conditioning Is Appropriate

    1.5 Randomization and Permutation

    1.6 Computational Aspects

    1.7 Basic Notation

    1.8 A Problem with Paired Observations

    1.9 The Permutation Solution

    1.10 A Two-Sample Problem

    1.11 One-Way ANOVA

    2 Theory of One-Dimensional Permutation Tests

    2.1 Introduction

    2.2 Definition of Permutation Tests

    2.3 Some Useful Test Statistics

    2.4 Equivalence of Permutation Statistics

    2.5 Arguments for Selecting Permutation Tests

    2.6 Examples of One-Sample Problems

    2.7 Examples of Multi-sample Problems

    2.8 Analysis of Ordered Categorical Variables

    2.9 Problems and Exercises

    3 Further Properties of Permutation Tests

    3.1 Unbiasedness of Two-sample Tests

    3.2 Power Functions of Permutation Tests

    3.3 Consistency of Permutation Tests

    3.4 Permutation Confidence Interval for δ

    3.5 Extending Inference from Conditional to Unconditional

    3.6 Optimal Properties

    3.7 Some Asymptotic Properties

    3.8 Permutation Central Limit Theorems

    3.9 Problems and Exercises

    4 The Nonparametric Combination Methodology

    4.1 Introduction

    4.2 The Nonparametric Combination Methodology

    4.3 Consistency, Unbiasedness and Power of Combined Tests

    4.4 Some Further Asymptotic Properties

    4.5 Finite-Sample Consistency

    4.6 Some Examples of Nonparametric Combination

    4.7 Comments on the Nonparametric Combination

    5 Multiple Testing Problems and Multiplicity Adjustment

    5.1 Defining Raw and Adjusted p-Values

    5.2 Controlling for Multiplicity

    5.3 Multiple Testing

    5.4 The Closed Testing Approach

    5.5 Mult Data Example

    5.6 Washing Test Data

    5.7 Weighted Methods for Controlling FWE and FDR

    5.8 Adjusting Stepwise p-Values

    6 Analysis of Multivariate Categorical Variables

    6.1 Introduction

    6.2 The Multivariate McNemar Test

    6.3 Multivariate Goodness-of-Fit Testing for Ordered Variables

    6.4 MANOVA with Nominal Categorical Data

    6.5 Stochastic Ordering

    6.6 Multifocus Analysis

    6.7 Isotonic Inference

    6.8 Test on Moments for Ordered Variables

    6.9 Heterogeneity Comparisons

    6.10 Application to PhD Programme Evaluation Using SAS

    7 Permutation Testing for Repeated Measurements

    7.1 Introduction

    7.2 Carry-Over Effects in Repeated Measures Designs

    7.3 Modelling Repeated Measurements

    7.4 Testing Solutions

    7.5 Testing for Repeated Measurements with Missing Data

    7.6 General Aspects of Permutation Testing with Missing Data

    7.7 On Missing Data Processes

    7.8 The Permutation Approach

    7.9 The Structure of Testing Problems

    7.10 Permutation Analysis of Missing Values

    7.11 Germina Data: An Example of an MNAR Model

    7.12 Multivariate Paired Observations

    7.13 Repeated Measures and Missing Data

    7.14 Botulinum Data

    7.15 Waterfalls Data

    8 Some Stochastic Ordering Problems

    8.1 Multivariate Ordered Alternatives

    8.2 Testing for Umbrella Alternatives

    8.3 Analysis of Experimental Tumour Growth Curves

    8.4 Analysis of PERC Data

    9 NPC Tests for Survival Analysis

    9.1 Introduction and Main Notation

    9.2 Comparison of Survival Curves

    9.3 An Overview of the Literature

    9.4 Two NPC Tests

    9.5 An Application to a Biomedical Study

    10 NPC Tests in Shape Analysis

    10.1 Introduction

    10.2 A Brief Overview of Statistical Shape Analysis

    10.3 Inference with Shape Data

    10.4 NPC Approach to Shape Analysis

    10.5 NPC Analysis with Correlated Landmarks

    10.6 An Application to Mediterranean Monk Seal Skulls

    11 Multivariate Correlation Analysis and Two-Way ANOVA

    11.1 Autofluorescence Case Study

    11.2 Confocal Case Study

    11.3 Two-Way (M)ANOVA

    12 Some Case Studies Using NPC Test R. 10 and SAS Macros

    12.1 An Integrated Approach to Survival Analysis in Observational Studies

    12.2 Integrating Propensity Score and NPC Testing

    12.3 Further Applications with NPC Test R. 10 and SAS Macros

    12.4 A Comparison of Three Survival Curves

    12.5 Survival Analysis Using NPC Test and SAS

    12.6 Logistic Regression and NPC Test for Multivariate Analysis

    References

    Index

Permutation Tests for Complex Data

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A Hardback by Fortunato Pesarin, Luigi Salmaso

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    View other formats and editions of Permutation Tests for Complex Data by Fortunato Pesarin

    Publisher: John Wiley & Sons Inc
    Publication Date: 19/03/2010
    ISBN13: 9780470516416, 978-0470516416
    ISBN10: 0470516410

    Description

    Book Synopsis
    Complex multivariate testing problems are frequently encountered in many scientific disciplines, such as engineering, medicine and the social sciences. As a result, modern statistics needs permutation testing for complex data with low sample size and many variables, especially in observational studies.

    The Authors give a general overview on permutation tests with a focus on recent theoretical advances within univariate and multivariate complex permutation testing problems, this book brings the reader completely up to date with today's current thinking.

    Key Features:

    • Examines the most up-to-date methodologies of univariate and multivariate permutation testing.
    • Includes extensive software codes in MATLAB, R and SAS, featuring worked examples, and uses real case studies from both experimental and observational studies.
    • Includes a standalone free software NPC Test Release 10 with a graphical interface which allows practitioners from every scientifi

      Table of Contents
      Contents

      Preface

      Notation and Abbreviations

      1 Introduction

      1.1 On Permutation Analysis

      1.2 The Permutation Testing Principle

      1.3 Permutation Approaches

      1.4 When and Why Conditioning Is Appropriate

      1.5 Randomization and Permutation

      1.6 Computational Aspects

      1.7 Basic Notation

      1.8 A Problem with Paired Observations

      1.9 The Permutation Solution

      1.10 A Two-Sample Problem

      1.11 One-Way ANOVA

      2 Theory of One-Dimensional Permutation Tests

      2.1 Introduction

      2.2 Definition of Permutation Tests

      2.3 Some Useful Test Statistics

      2.4 Equivalence of Permutation Statistics

      2.5 Arguments for Selecting Permutation Tests

      2.6 Examples of One-Sample Problems

      2.7 Examples of Multi-sample Problems

      2.8 Analysis of Ordered Categorical Variables

      2.9 Problems and Exercises

      3 Further Properties of Permutation Tests

      3.1 Unbiasedness of Two-sample Tests

      3.2 Power Functions of Permutation Tests

      3.3 Consistency of Permutation Tests

      3.4 Permutation Confidence Interval for δ

      3.5 Extending Inference from Conditional to Unconditional

      3.6 Optimal Properties

      3.7 Some Asymptotic Properties

      3.8 Permutation Central Limit Theorems

      3.9 Problems and Exercises

      4 The Nonparametric Combination Methodology

      4.1 Introduction

      4.2 The Nonparametric Combination Methodology

      4.3 Consistency, Unbiasedness and Power of Combined Tests

      4.4 Some Further Asymptotic Properties

      4.5 Finite-Sample Consistency

      4.6 Some Examples of Nonparametric Combination

      4.7 Comments on the Nonparametric Combination

      5 Multiple Testing Problems and Multiplicity Adjustment

      5.1 Defining Raw and Adjusted p-Values

      5.2 Controlling for Multiplicity

      5.3 Multiple Testing

      5.4 The Closed Testing Approach

      5.5 Mult Data Example

      5.6 Washing Test Data

      5.7 Weighted Methods for Controlling FWE and FDR

      5.8 Adjusting Stepwise p-Values

      6 Analysis of Multivariate Categorical Variables

      6.1 Introduction

      6.2 The Multivariate McNemar Test

      6.3 Multivariate Goodness-of-Fit Testing for Ordered Variables

      6.4 MANOVA with Nominal Categorical Data

      6.5 Stochastic Ordering

      6.6 Multifocus Analysis

      6.7 Isotonic Inference

      6.8 Test on Moments for Ordered Variables

      6.9 Heterogeneity Comparisons

      6.10 Application to PhD Programme Evaluation Using SAS

      7 Permutation Testing for Repeated Measurements

      7.1 Introduction

      7.2 Carry-Over Effects in Repeated Measures Designs

      7.3 Modelling Repeated Measurements

      7.4 Testing Solutions

      7.5 Testing for Repeated Measurements with Missing Data

      7.6 General Aspects of Permutation Testing with Missing Data

      7.7 On Missing Data Processes

      7.8 The Permutation Approach

      7.9 The Structure of Testing Problems

      7.10 Permutation Analysis of Missing Values

      7.11 Germina Data: An Example of an MNAR Model

      7.12 Multivariate Paired Observations

      7.13 Repeated Measures and Missing Data

      7.14 Botulinum Data

      7.15 Waterfalls Data

      8 Some Stochastic Ordering Problems

      8.1 Multivariate Ordered Alternatives

      8.2 Testing for Umbrella Alternatives

      8.3 Analysis of Experimental Tumour Growth Curves

      8.4 Analysis of PERC Data

      9 NPC Tests for Survival Analysis

      9.1 Introduction and Main Notation

      9.2 Comparison of Survival Curves

      9.3 An Overview of the Literature

      9.4 Two NPC Tests

      9.5 An Application to a Biomedical Study

      10 NPC Tests in Shape Analysis

      10.1 Introduction

      10.2 A Brief Overview of Statistical Shape Analysis

      10.3 Inference with Shape Data

      10.4 NPC Approach to Shape Analysis

      10.5 NPC Analysis with Correlated Landmarks

      10.6 An Application to Mediterranean Monk Seal Skulls

      11 Multivariate Correlation Analysis and Two-Way ANOVA

      11.1 Autofluorescence Case Study

      11.2 Confocal Case Study

      11.3 Two-Way (M)ANOVA

      12 Some Case Studies Using NPC Test R. 10 and SAS Macros

      12.1 An Integrated Approach to Survival Analysis in Observational Studies

      12.2 Integrating Propensity Score and NPC Testing

      12.3 Further Applications with NPC Test R. 10 and SAS Macros

      12.4 A Comparison of Three Survival Curves

      12.5 Survival Analysis Using NPC Test and SAS

      12.6 Logistic Regression and NPC Test for Multivariate Analysis

      References

      Index

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