Description
Book SynopsisFrom the Foreword by Candy Cooley, formerly Genetics Awareness Programme Lead at the NHS National Genetics and Genomics Education Centre:
“What a delight it is … to read a book which takes complex scientific concepts and ensures they are understandable by all.” With activities and answers, reflection points and a glossary, this interactive textbook supports the ‘Fit for Practice in the Genetics Era’ competence framework, offering an introduction to the theory of genetics and then using common genetic conditions/disorders as case studies to help students apply theory to practice and examine the service user experience.
Genetics is written by an experienced teacher of health care sciences and is ideal for student nurses who need to demonstrate and apply knowledge of genetics and genomics. It is also suitable for other health care students and for qualified practitioners who would like to refresh their knowledge of the subject.
From lecturer reviews: “A well written and nicely laid out genetics text at an appropriate level for adult nursing students.” “Fabulous text, student friendly.”Table of ContentsForeword; Introduction
1. Basic cell biology
1.1 Introduction
1.2 Chromosomes
1.3 Chromosomal inheritance
1.4 Genetic information
1.5 Protein
1.6 Mitochondrial DNA
1.7 The classification of genetic material
2. Inheritance
2.1 Introduction
2.2 Exceptions to the rules
3. Autosomal recessive and dominant inheritance
3.1 Introduction
3.2 Autosomal recessive inheritance
3.3 Autosomal dominant inheritance
3.4 Classification of gene action
3.5 Co-dominance
3.6 Multiple alleles
3.7 Lethal alleles
4. Sex-linked inheritance
4.1 Introduction
4.2 The X chromosome
4.3 The Y chromosome
4.4 Sexual development
4.5 The inheritance of sex
4.6 Sex-linked inheritance
4.7 X inactivation
4.8 Sex-linked genetic effects
5. Two or more genes
5.1 Introduction
5.2 Monogenic inheritance
5.3 Polygenic inheritance
5.4 Multifactorial inheritance
5.5 Common multifactorial disorders
5.6 Identifying the genes in multifactorial conditions
6. Mutations
6.1 Introduction
6.2 Chromosomal mutations
6.3 Gene mutations
7. Pedigree analysis
7.1 Introduction
7.2 Modes of inheritance
7.3 Problems with pedigree analysis
8. Clinical applications
8.1 Screening and testing
8.2 Gene therapy
8.3 Pharmacogenetics
9. Cancer genetics
9.1 Introduction
9.2 Oncogenes
9.3 Tumour-suppressor genes
9.4 Environmental triggers
9.5 Other cancer considerations
10. Genetic counselling
10.1 Introduction
10.2 UK genetic services
10.3 Genetic counselling
10.4 Becoming a genetic counsellor
10.5 Making an appropriate referral
10.6 Genetic counselling for tests
10.7 Ethical issues
10.6 Internet resources for genetic education
Answers to the activities; Glossary; Index
